Mrps18b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye alternative polyA XM_039098476.2 0.44 0.18 1.9e-03 0.04 0.06 -0.02 0.01 8.6e-02 5.1e-02 6.9e-01 2.5e-01
2 Eye alternative polyA NM_212534.2 0.43 0.18 2.2e-03 0.04 0.05 -0.02 0.01 8.8e-02 5.8e-02 8.5e-01 2.3e-01
3 Adipose gene expression Mrps18b 0.28 0.1 0.0e+00 0.34 0.35 0.36 0.36 1.1e-38 2.6e-40 4.1e-41 6.3e-41
4 OFC intron excision ratio chr20_2844761_2847874 0.18 0.12 4.8e-03 0.1 0.1 0.06 0.08 2.4e-03 2.5e-03 1.6e-02 5.5e-03
5 Brain gene expression Mrps18b 0.44 0.09 0.0e+00 0.47 0.49 0.49 0.49 3.5e-49 2.2e-51 2.5e-52 8.2e-52
6 LHb gene expression Mrps18b 0.5 0.19 2.2e-09 0.3 0.26 0.34 0.27 6.1e-08 9.1e-07 6.9e-09 4.0e-07
7 IL gene expression Mrps18b 0.38 0.17 2.4e-06 0.16 0.16 0.16 0.2 1.5e-04 1.4e-04 9.3e-05 1.2e-05
8 Liver mRNA stability Mrps18b 0.04 0.03 1.9e-03 0.03 0.02 0.03 0.03 6.9e-04 2.3e-03 7.1e-04 8.2e-04
9 RMTg gene expression Mrps18b 0.25 0.14 7.1e-05 0.12 0.08 0.13 0.11 4.0e-04 4.7e-03 2.5e-04 8.6e-04
10 PL alternative TSS XM_039098476.2 0.05 0.04 1.3e-03 0.02 0.02 0.02 0.02 4.0e-03 4.5e-03 3.8e-03 1.8e-03
11 IC gene expression Mrps18b 0.38 0.12 1.9e-15 0.31 0.25 0.28 0.22 1.2e-13 9.0e-11 2.3e-12 1.2e-09
12 Eye gene expression Mrps18b 0.4 0.19 1.0e-03 0.09 0.11 0.09 0.09 1.9e-02 1.0e-02 1.8e-02 2.0e-02
13 pVTA gene expression Mrps18b 0.26 0.1 0.0e+00 0.31 0.22 0.32 0.24 4.3e-25 9.0e-18 1.4e-26 3.4e-19
14 BLA gene expression Mrps18b 0.31 0.12 0.0e+00 0.22 0.27 0.25 0.26 5.2e-12 9.6e-15 1.9e-13 5.6e-14
15 OFC gene expression Mrps18b 0.4 0.16 3.2e-07 0.16 0.21 0.2 0.2 1.2e-04 9.3e-06 1.5e-05 1.3e-05
16 PL alternative TSS NM_212534.2 0.05 0.04 1.1e-03 0.02 0.02 0.02 0.02 3.5e-03 5.0e-03 2.4e-03 1.3e-03
17 Liver gene expression Mrps18b 0.49 0.1 0.0e+00 0.52 0.54 0.54 0.54 2.1e-66 6.1e-72 9.1e-71 3.5e-71
18 NAcc gene expression Mrps18b 0.24 0.06 0.0e+00 0.41 0.42 0.43 0.43 6.6e-68 1.6e-69 1.3e-70 1.0e-70
19 PL gene expression Mrps18b 0.34 0.12 0.0e+00 0.34 0.36 0.36 0.37 1.2e-38 3.6e-41 2.7e-41 3.2e-42
20 Adipose mRNA stability Mrps18b 0.03 0.02 2.4e-03 0.01 0.01 0.01 0.01 7.2e-03 9.9e-03 5.6e-02 5.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.91.53.82.0-2.00.8-0.80.70.91.80.91.61.20.80.90.80.80.9-1.41.21.00.8-1.7
Area under the delay curve1.61.82.4-1.21.2-1.21.6-1.3-1.4-1.4-1.2-1.4-1.4-1.0-1.4-1.3-1.4-1.41.4-1.4-1.5-1.31.4
BMI with tail1.76.09.3-0.90.9-3.02.6-2.8-2.5-2.2-2.4-2.7-2.5-3.0-2.6-2.5-2.7-2.72.4-2.4-2.6-2.71.6
BMI without tail3.611.013.9-2.12.2-3.63.7-3.6-3.6-3.1-3.4-3.3-3.3-3.7-3.6-3.4-3.6-3.53.2-3.4-3.5-3.52.3
Body weight5.825.231.4-5.45.5-4.94.6-4.4-4.9-5.6-4.6-5.4-5.0-5.0-5.1-4.8-5.0-4.85.1-5.4-5.0-4.84.9
Weight adjusted by age2.03.05.1-2.32.3-1.51.9-1.4-1.4-2.2-1.1-1.8-1.8-1.5-1.6-1.5-1.5-1.51.9-1.8-1.4-1.42.2
Bone surface0.00.10.5-0.70.70.10.2-0.1-0.1-0.3-0.1-0.0-0.1-0.2-0.1-0.1-0.1-0.00.1-0.2-0.1-0.1-0.1
Bone volume0.10.10.2-0.10.1-0.40.5-0.5-0.4-0.1-0.40.0-0.3-0.4-0.4-0.4-0.4-0.40.1-0.4-0.4-0.4-0.0
Breakpoint value in progressive ratio session0.30.40.70.5-0.50.5-0.70.60.40.60.10.70.70.90.70.80.70.7-0.70.70.70.8-0.2
Number of licking bursts0.40.71.3-0.30.31.1-1.01.00.90.30.80.30.41.21.11.01.11.0-0.20.80.91.0-0.5
Context. condit. distance diff. score8.710.512.91.4-1.53.6-3.43.63.43.13.43.33.33.53.43.53.43.5-3.23.23.53.5-2.8
Locomotion velocity, session 10.50.61.00.1-0.10.8-0.90.90.90.51.00.60.70.90.80.90.80.8-0.70.70.80.9-0.4
Locomotion distance, session 10.10.21.11.1-1.1-0.10.0-0.10.10.60.20.20.20.00.10.00.10.0-0.20.30.1-0.0-0.4
Locomotion velocity, session 20.10.10.2-0.20.20.3-0.40.30.30.00.40.10.20.20.30.30.30.3-0.10.20.30.30.3
Locomotion distance, session 20.20.20.60.7-0.70.4-0.40.40.50.50.60.50.50.40.50.50.50.4-0.50.50.50.4-0.1
Locomotion velocity, session 30.20.20.40.3-0.3-0.60.6-0.7-0.5-0.0-0.5-0.1-0.4-0.6-0.5-0.6-0.6-0.50.2-0.4-0.5-0.6-0.0
Locomotion distance, session 31.21.32.21.4-1.41.0-0.90.91.01.50.91.51.21.01.01.01.01.0-1.31.21.11.0-1.5
Stereotopy head waving bouts, day 31.11.33.8-1.91.9-0.70.7-0.6-0.8-1.7-0.6-1.4-1.2-0.6-0.8-0.7-0.7-0.71.3-1.1-0.7-0.61.7
Stereotopy head waving duration, day 30.91.12.5-1.61.6-0.70.8-0.7-0.8-1.5-0.6-1.4-1.1-0.6-0.8-0.7-0.7-0.81.3-1.0-0.8-0.61.5
Locomotion velocity, session 74.85.36.82.2-2.22.2-2.32.22.42.62.32.62.52.02.22.32.22.3-2.52.42.32.1-2.4
Locomotion distance, session 73.54.46.42.4-2.41.9-1.91.82.02.52.02.42.21.62.01.91.91.9-2.32.22.01.8-2.5
Stereotopy head waving bouts, day 72.93.24.7-1.91.9-1.71.6-1.6-1.7-2.1-1.6-2.0-1.9-1.7-1.7-1.7-1.6-1.72.0-1.9-1.7-1.62.2
Stereotopy head waving duration, day 72.83.35.0-2.02.0-1.71.7-1.6-1.7-2.1-1.6-2.0-1.9-1.7-1.7-1.7-1.7-1.72.0-1.9-1.7-1.62.2
Locomotion velocity, session 81.31.53.0-1.41.31.5-1.41.71.3-0.11.40.40.91.51.31.41.41.4-0.50.81.31.50.5
Locomotion distance, session 84.66.78.21.2-1.32.9-2.72.92.82.52.82.72.72.82.72.82.72.8-2.72.62.72.8-2.0
Degree of sensitization distance0.70.71.2-0.00.01.0-1.01.11.00.41.10.50.70.81.01.01.01.0-0.60.80.90.9-0.5
Degree of sensitization stereotypy1.41.51.9-1.11.1-1.21.1-1.2-1.2-1.3-1.2-1.3-1.3-1.3-1.2-1.2-1.2-1.21.3-1.3-1.2-1.21.4
Conditioned locomotion0.50.61.6-1.21.2-0.50.6-0.5-0.6-1.1-0.5-0.9-0.8-0.5-0.6-0.5-0.5-0.60.8-0.8-0.5-0.51.3
Cocaine response after cond. corrected0.40.50.90.8-0.80.7-0.60.60.70.80.60.80.70.80.70.70.70.7-0.70.80.70.7-0.9
Cocaine response after cond. not corrected0.10.10.5-0.70.70.2-0.20.20.1-0.30.2-0.2-0.00.30.20.20.20.20.10.00.10.20.2
Cocaine response before conditioning3.33.99.2-3.03.0-1.51.5-1.4-1.7-2.5-1.6-2.3-1.9-1.5-1.8-1.6-1.7-1.62.0-2.1-1.7-1.52.6
Saline control response2.43.14.7-0.50.5-2.12.0-2.2-2.0-1.3-1.9-1.5-1.7-1.9-2.0-2.1-2.1-2.01.6-1.8-2.0-2.00.9
Bone: connectivity density2.33.65.02.0-2.01.8-1.71.61.82.21.82.22.01.71.81.71.71.8-2.11.91.81.8-2.2
Bone: cortical apparent density0.70.91.50.4-0.4-1.21.1-1.2-1.1-0.5-1.2-0.5-0.7-1.1-1.1-1.1-1.1-1.20.6-0.9-1.0-1.10.7
Bone: cortical area1.62.52.9-1.61.6-1.51.5-1.4-1.5-1.7-1.5-1.7-1.6-1.7-1.6-1.5-1.5-1.51.6-1.7-1.5-1.51.6
Bone: cortical porosity0.70.81.1-0.70.8-0.80.9-0.8-0.9-1.0-1.0-0.9-0.9-1.0-0.9-0.9-0.8-0.90.9-0.9-0.9-1.00.7
Bone: cortical porosity0.40.51.1-1.11.1-0.40.6-0.5-0.5-1.0-0.6-0.9-0.7-0.7-0.5-0.5-0.5-0.50.8-0.6-0.6-0.60.7
Bone: cortical thickness4.37.19.3-0.80.9-3.13.0-3.0-2.9-2.1-2.9-2.3-2.6-3.0-3.0-3.0-3.0-3.02.4-2.7-2.9-3.02.0
Bone: cortical thickness1.92.23.80.4-0.3-2.01.7-1.9-1.5-1.1-1.5-1.3-1.3-1.8-1.7-1.7-1.7-1.81.2-1.4-1.6-1.80.6
Bone: cortical tissue density0.50.71.20.4-0.4-1.11.0-1.0-0.9-0.4-1.1-0.4-0.6-1.0-1.0-1.0-1.0-1.00.5-0.8-0.9-1.00.6
Condit. Reinf. active minus inactive responses0.91.01.30.9-0.91.0-0.91.01.01.11.11.11.11.00.90.90.90.9-1.11.01.01.0-0.7
Condit. Reinf. active-inactive response ratio0.10.10.20.2-0.2-0.40.2-0.4-0.3-0.2-0.2-0.3-0.2-0.3-0.3-0.3-0.3-0.30.2-0.2-0.3-0.30.2
Condit. Reinf. active responses1.41.72.71.4-1.41.3-1.21.11.31.61.21.61.41.31.21.21.11.2-1.61.31.21.2-1.2
Condit. Reinf. inactive responses1.92.34.52.1-2.11.3-1.11.11.22.11.12.01.61.31.21.21.11.2-1.81.41.21.2-1.9
Incentive salience index mean2.32.83.80.7-0.71.9-1.81.91.81.51.91.71.81.91.71.71.81.8-1.71.61.81.8-1.1
Condit. Reinf. lever presses4.25.98.00.8-0.92.8-2.62.82.72.12.82.42.52.62.62.62.62.7-2.42.42.62.6-1.8
Condit. Reinf. active minus inactive responses0.81.02.0-1.41.4-0.60.8-0.8-0.8-1.3-0.8-1.2-1.0-0.6-0.9-0.9-0.8-0.91.1-1.0-0.9-0.81.3
Condit. Reinf. active-inactive response ratio1.71.94.5-2.12.1-0.91.0-1.0-1.1-1.9-1.1-1.7-1.4-0.9-1.1-1.1-1.0-1.11.5-1.4-1.2-1.12.0
Condit. Reinf. active responses0.10.10.3-0.00.00.5-0.20.30.40.20.40.30.30.60.30.20.30.2-0.30.20.20.3-0.1
Condit. Reinf. inactive responses1.62.13.41.6-1.71.3-1.11.21.41.81.31.71.61.41.21.21.21.3-1.71.41.31.3-1.8
Condit. Reinf. lever presses0.81.11.40.8-0.81.1-1.01.11.11.21.11.01.01.21.11.01.11.0-1.01.11.01.1-1.0
Condit. Reinf. lever reinforcers received0.20.20.60.1-0.10.7-0.40.50.50.40.50.50.50.80.50.40.50.4-0.50.40.40.6-0.2
Conditioned reinforcement - actives1.11.93.6-0.70.7-1.21.9-1.4-1.7-0.6-1.7-1.3-1.5-1.3-1.4-1.5-1.5-1.41.4-1.4-1.4-1.31.1
Conditioned reinforcement - inactives1.42.03.2-0.60.7-1.21.7-1.6-1.7-0.8-1.8-1.3-1.6-1.2-1.5-1.6-1.5-1.51.5-1.4-1.5-1.31.5
Conditioned locomotion0.10.20.4-0.60.60.10.4-0.3-0.4-0.0-0.6-0.2-0.5-0.2-0.4-0.3-0.4-0.30.4-0.4-0.5-0.40.4
Patch foraging indifference point 0 sec0.71.32.50.4-0.4-1.41.5-1.4-1.4-0.6-1.6-0.9-1.2-1.2-1.2-1.3-1.3-1.31.1-1.0-1.1-1.10.1
Patch foraging indifference point AUC0.91.31.9-1.41.4-0.90.9-1.1-1.0-1.2-1.0-1.2-1.2-1.1-1.2-1.1-1.2-1.21.2-1.3-1.3-1.21.0
Delay disc. indifference point, 0s delay0.30.30.9-1.01.0-0.30.9-0.2-0.3-0.7-0.1-0.6-0.5-0.2-0.4-0.5-0.4-0.40.5-0.5-0.5-0.30.8
Delay disc. indifference point, 16s delay2.52.74.1-0.40.4-1.71.9-2.0-1.9-1.2-1.8-1.4-1.7-1.5-1.9-1.9-1.9-2.01.6-1.6-2.0-1.80.9
Delay disc. indifference point, 2s delay1.61.83.2-1.71.7-1.11.4-1.0-1.2-1.8-0.9-1.7-1.5-0.9-1.1-1.1-1.0-1.11.6-1.3-1.2-1.01.7
Delay disc. indifference point, 24s delay0.60.61.2-0.30.3-0.80.6-0.8-0.9-0.7-1.1-0.8-0.9-1.1-0.8-0.8-0.8-0.80.9-0.7-0.9-1.00.5
Delay disc. indifference point, 4s delay2.22.34.2-2.02.0-1.21.5-1.2-1.5-1.8-1.0-1.5-1.4-0.8-1.5-1.4-1.4-1.41.4-1.6-1.5-1.22.1
Delay disc. indifference point, 8s delay0.30.30.7-0.40.4-0.50.8-0.6-0.5-0.5-0.5-0.6-0.6-0.4-0.6-0.6-0.6-0.70.6-0.6-0.7-0.60.7
Indifference point function ln k0.30.50.90.1-0.10.8-0.80.90.90.30.90.50.80.70.90.80.90.9-0.60.80.90.8-0.3
Indifference point function log k0.30.50.90.1-0.10.8-0.80.90.90.30.90.50.80.70.90.80.90.9-0.60.80.90.8-0.3
Patch foraging total patch changes 0 sec1.01.83.30.3-0.3-1.61.8-1.6-1.6-0.7-1.8-1.1-1.4-1.5-1.5-1.6-1.5-1.51.3-1.2-1.4-1.40.2
Patch foraging total patch changes 12 sec1.51.92.90.0-0.0-1.61.7-1.6-1.5-0.8-1.5-1.3-1.5-1.6-1.5-1.6-1.5-1.61.4-1.3-1.5-1.60.4
Patch foraging total patch changes 18 sec0.71.11.71.1-1.1-1.21.2-1.3-1.10.0-1.3-0.4-0.8-1.1-1.1-1.1-1.2-1.20.6-0.8-1.1-1.2-0.6
Patch foraging total patch changes 24 sec0.40.63.41.8-1.8-0.70.6-0.8-0.50.8-0.70.3-0.3-0.7-0.5-0.5-0.6-0.6-0.0-0.0-0.4-0.5-1.0
Patch foraging total patch changes 6 sec1.32.03.30.6-0.5-1.81.5-1.8-1.6-0.7-1.6-1.3-1.5-1.6-1.5-1.6-1.6-1.61.4-1.2-1.4-1.50.2
Patch foraging time to switch 0 sec0.10.21.31.1-1.1-0.20.1-0.2-0.00.50.00.40.2-0.10.0-0.1-0.1-0.1-0.30.20.00.0-0.5
Patch foraging water rate 0 sec0.51.22.2-0.80.8-1.20.9-1.0-0.9-1.3-0.9-1.5-1.2-1.2-1.0-0.9-1.0-1.11.3-1.0-1.0-1.11.2
Patch foraging water rate 12 sec0.00.10.30.6-0.6-0.30.3-0.4-0.30.3-0.10.2-0.1-0.3-0.3-0.3-0.3-0.4-0.0-0.2-0.3-0.40.2
Patch foraging water rate 18 sec0.10.20.4-0.60.6-0.30.2-0.5-0.5-0.2-0.5-0.2-0.4-0.3-0.5-0.4-0.5-0.40.3-0.6-0.4-0.30.7
Patch foraging water rate 24 sec1.72.44.0-1.21.2-1.71.0-1.6-1.4-1.5-1.4-1.6-1.4-2.0-1.7-1.5-1.6-1.71.4-1.7-1.7-1.81.5
Patch foraging water rate 6 sec0.10.20.40.3-0.3-0.60.4-0.6-0.4-0.0-0.4-0.4-0.4-0.5-0.5-0.5-0.5-0.60.4-0.4-0.6-0.60.1
Seeking ratio, delayed vs. immediate footshock0.30.40.8-0.80.8-0.70.7-0.7-0.7-0.9-0.6-0.6-0.4-0.1-0.6-0.4-0.6-0.60.4-0.7-0.5-0.20.9
Distance traveled before self-admin0.10.10.7-0.80.80.5-0.00.30.3-0.20.20.20.40.20.20.10.20.3-0.3-0.00.30.20.4
Distance traveled after self-admin0.70.82.3-1.51.5-0.80.7-0.7-1.0-1.2-0.7-0.9-0.9-0.6-0.7-0.7-0.7-0.61.0-0.9-0.7-0.60.7
Extensor digitorum longus weight0.00.20.4-0.60.60.5-0.20.60.30.20.30.40.30.30.30.30.30.5-0.30.20.40.4-0.6
Bone: elastic displacement0.60.61.10.1-0.1-1.10.8-1.0-1.0-0.6-0.9-0.8-0.9-0.9-0.8-0.8-0.8-0.90.8-0.7-0.8-0.90.3
Bone: elastic work2.73.54.6-1.31.3-2.01.9-1.9-2.0-2.0-1.9-2.1-2.1-2.0-1.9-1.9-1.8-1.92.1-1.9-1.8-1.91.7
Bone: endosteal estimation0.81.812.3-3.53.50.20.00.3-0.2-1.9-0.1-1.4-0.8-0.2-0.2-0.1-0.10.01.2-0.9-0.3-0.01.9
Bone: endosteal perimeter0.91.93.6-1.71.61.8-1.61.91.50.11.50.50.91.41.51.61.61.7-0.60.91.41.6-0.1
Epididymis fat weight3.913.423.61.9-1.8-4.94.2-4.7-4.1-1.6-4.5-2.8-3.3-4.2-4.0-4.0-4.3-4.42.9-3.1-3.9-4.11.3
Delta time in closed arm before/after self-admin0.50.50.9-0.50.5-0.70.5-0.8-0.6-0.9-0.6-1.0-0.8-0.8-0.6-0.5-0.6-0.70.9-0.6-0.7-0.70.7
Delta time in open arm before/after self-admin0.20.20.7-0.50.5-0.30.7-0.1-0.60.0-0.4-0.2-0.2-0.3-0.5-0.6-0.5-0.40.1-0.5-0.3-0.40.8
Diff in mean of infusions in LGA sessions3.64.46.72.4-2.52.2-1.81.81.82.61.52.42.22.02.11.92.02.0-2.32.32.01.9-1.8
Delay discount exponential model param1.71.92.41.3-1.31.2-1.51.31.41.51.21.41.51.11.41.31.41.4-1.41.51.51.4-1.5
Extinction: sum of active levers before priming0.50.50.90.6-0.60.8-0.70.70.50.40.50.70.60.90.90.80.90.8-0.60.90.90.9-0.4
Active lever presses in extinction session 60.10.10.70.8-0.8-0.30.3-0.3-0.20.1-0.10.10.0-0.0-0.1-0.2-0.2-0.1-0.10.1-0.2-0.0-0.6
Bone: final force6.410.312.1-2.22.3-3.53.4-3.3-3.3-3.2-3.2-3.4-3.4-3.4-3.3-3.3-3.3-3.33.3-3.3-3.3-3.32.7
Bone: final moment5.58.910.4-2.22.2-3.23.1-3.1-3.1-3.0-3.0-3.1-3.1-3.2-3.1-3.1-3.1-3.13.1-3.1-3.0-3.02.5
Food consumed during 24 hour testing period0.30.41.7-1.31.3-0.30.2-0.1-0.2-0.9-0.1-0.6-0.4-0.5-0.4-0.3-0.4-0.30.4-0.6-0.3-0.31.1
Glucose2.94.67.9-0.80.72.8-2.52.82.41.12.51.72.12.52.32.42.42.4-1.91.82.32.5-0.5
Heart weight2.23.45.1-1.71.7-1.81.9-1.8-1.8-2.3-1.7-2.3-1.9-2.0-1.7-1.8-1.7-1.72.1-1.8-1.8-1.91.3
Delay discount hyperbolic model param1.82.02.51.3-1.31.2-1.51.31.51.61.21.61.51.21.41.41.41.5-1.51.51.61.4-1.6
Intermittent access intake day 1-15 change0.00.00.20.1-0.10.2-0.10.20.30.10.40.30.10.10.20.30.20.2-0.20.20.20.0-0.4
Intermittent access intake escalation0.00.10.20.1-0.0-0.30.5-0.3-0.2-0.1-0.10.1-0.2-0.3-0.4-0.2-0.4-0.30.1-0.3-0.3-0.4-0.2
Intermittent access intake escalation 20.20.20.8-0.60.60.4-0.30.40.7-0.10.90.30.30.40.30.40.30.4-0.30.10.20.2-0.2
Intermitt. access day 1 inactive lever presses0.10.31.7-1.31.30.3-0.20.1-0.1-0.70.3-0.6-0.6-0.40.00.00.1-0.00.8-0.3-0.2-0.21.1
Intermitt. access day 15 inactive lever presses0.71.42.2-1.41.4-1.11.0-1.1-1.0-1.5-0.6-1.4-1.3-1.4-1.2-1.1-1.1-1.11.3-1.3-1.2-1.31.0
Intermitt. access escalation Index2.83.95.01.6-1.62.1-2.02.21.92.21.71.91.91.82.12.02.12.1-1.92.12.12.0-1.6
Intermittent access day 1 total infusions0.10.21.00.8-0.80.00.50.0-0.61.0-1.00.40.10.1-0.0-0.1-0.1-0.0-0.20.20.10.2-0.2
Intermittent access day 15 total infusions0.20.21.20.4-0.4-0.40.9-0.4-0.80.4-1.10.1-0.3-0.3-0.5-0.4-0.5-0.40.1-0.3-0.3-0.30.0
Intermittent access terminal intake (last 3 days)0.50.61.60.0-0.0-0.81.3-0.9-1.1-0.1-1.3-0.5-0.9-0.7-0.8-0.9-0.9-0.80.7-0.7-0.8-0.80.5
Intermittent access total infusions0.30.41.80.1-0.1-0.41.0-0.5-1.00.4-1.3-0.2-0.6-0.4-0.6-0.7-0.7-0.50.4-0.4-0.5-0.50.2
Intermittent access day 1 locomotion0.10.20.70.4-0.40.3-0.00.4-0.10.9-0.60.70.50.40.20.30.20.4-0.60.40.40.5-0.3
Intermittent access day 15 total locomotion0.61.22.1-1.41.4-0.51.2-0.9-1.2-0.5-1.5-0.8-1.1-0.6-1.1-1.0-1.1-1.01.0-1.2-1.1-0.91.0
Intermittent access total locomotion0.80.92.4-1.11.1-0.61.3-0.8-1.2-0.3-1.6-0.6-0.9-0.7-1.1-0.9-1.1-0.90.8-1.1-1.0-0.80.9
Intermittent access standard deviation1.73.64.9-1.11.1-2.02.2-2.2-2.0-1.6-1.8-1.8-2.1-2.0-2.1-2.0-2.1-2.01.9-2.0-2.0-2.11.5
Left kidney weight4.520.823.8-4.24.3-4.84.5-4.4-4.5-4.8-4.4-4.9-4.4-4.7-4.7-4.5-4.7-4.54.5-4.9-4.6-4.64.0
Right kidney weight4.520.724.4-4.64.6-4.64.6-4.3-4.5-4.8-4.3-4.7-4.5-4.3-4.8-4.5-4.6-4.54.5-4.9-4.5-4.44.3
Cocaine induced anxiety0.81.11.80.2-0.21.3-1.31.41.20.71.11.01.11.11.21.21.21.2-1.11.01.11.1-0.6
Post-drug Anxiety0.60.71.40.4-0.40.8-0.80.91.10.11.20.70.90.70.90.91.00.9-0.80.90.90.8-0.8
Baseline Anxiety0.20.21.31.1-1.1-0.20.3-0.20.3-0.20.40.00.00.00.20.10.2-0.0-0.00.40.20.2-0.9
Tail length2.610.028.2-5.35.3-2.12.5-1.9-2.8-4.1-2.5-3.2-2.9-2.3-2.8-2.6-2.6-2.43.1-3.4-2.8-2.43.7
Length with tail3.615.743.1-6.66.5-2.83.0-2.4-3.4-5.1-3.1-4.1-3.7-2.9-3.5-3.3-3.3-3.03.9-4.3-3.5-3.14.7
Length without tail3.812.324.6-5.05.0-3.02.8-2.5-3.0-4.4-2.8-4.0-3.4-2.9-3.2-3.0-3.0-2.93.7-3.7-3.2-3.04.1
Times rat made contact with spout0.60.73.61.9-1.9-0.1-0.20.00.31.20.30.70.50.00.30.20.20.3-0.60.70.30.2-1.5
Lifetime Intake0.60.72.4-0.20.2-0.61.5-0.7-1.20.1-1.6-0.4-0.8-0.5-0.8-0.9-0.9-0.80.7-0.7-0.7-0.60.5
Liver weight, left0.40.64.1-2.02.00.4-0.50.80.3-0.70.5-0.30.10.40.40.50.50.60.1-0.10.50.60.8
Liver weight, right1.11.99.8-3.13.1-0.50.7-0.1-0.8-1.8-0.6-1.4-1.1-0.6-0.7-0.6-0.6-0.51.3-1.2-0.6-0.51.9
Locomotor activity0.40.64.4-2.12.10.2-0.30.40.5-0.90.8-0.7-0.20.20.10.20.20.20.4-0.40.00.10.5
Locomotor testing distance0.10.20.9-0.90.90.5-0.50.50.7-0.30.8-0.10.20.20.40.40.50.4-0.00.10.30.3-0.3
Locomotor testing rearing0.10.21.5-1.21.2-0.1-0.10.10.1-0.80.0-0.5-0.1-0.3-0.1-0.0-0.0-0.00.2-0.4-0.1-0.20.5
Locomotion in novel chamber0.60.71.3-0.90.9-0.71.1-0.9-0.9-0.7-0.6-0.9-0.9-0.6-1.0-0.9-1.0-0.90.9-1.0-1.0-0.60.4
Locomotion in novel chamber post-restriction1.01.62.9-0.70.8-1.41.7-1.4-1.2-1.4-0.8-1.5-1.4-1.3-1.3-1.3-1.3-1.31.4-1.3-1.2-1.11.2
Fecal boli incidents, locomotor time 10.40.61.30.9-1.00.7-1.00.60.31.0-0.10.90.50.70.80.80.70.8-0.60.90.90.9-1.1
Change in fecal boli incidents, locomotor task1.00.92.3-1.21.2-0.80.9-0.7-0.7-1.5-0.7-1.4-1.0-1.0-0.7-0.7-0.6-0.81.2-0.8-0.8-0.81.3
Time >=10cm from walls, locomotor time 10.40.51.8-1.41.3-0.40.2-0.1-0.4-1.1-0.3-0.9-0.7-0.6-0.2-0.1-0.2-0.10.9-0.4-0.3-0.31.0
Bouts of movement, locomotor time 11.31.53.40.5-0.51.1-1.41.41.51.01.91.01.51.31.21.01.21.2-1.41.11.31.3-1.1
Total resting periods, locomotor time 10.80.91.80.1-0.10.8-1.11.11.00.61.30.71.11.20.90.70.91.0-1.00.81.01.1-0.7
Rest time, locomotor task time 10.10.20.8-0.90.90.1-0.40.30.4-0.50.5-0.30.20.20.10.20.20.3-0.0-0.10.20.30.5
Distance moved, locomotor task time 10.61.01.7-0.30.4-1.01.0-1.2-1.2-0.8-0.9-0.9-1.3-0.9-1.0-1.1-1.0-1.01.2-0.9-1.0-1.10.6
Vertical activity count, locomotor time 10.20.50.9-0.10.1-0.90.8-0.8-0.7-0.6-0.7-0.7-0.9-0.8-0.7-0.8-0.7-0.80.9-0.7-0.7-1.00.4
Time >=10cm from walls, locomotor time 20.10.10.4-0.60.60.1-0.20.40.2-0.50.1-0.4-0.1-0.30.30.30.30.30.30.10.30.10.6
Bouts of movement, locomotor time 20.20.31.6-1.31.2-0.2-0.60.40.5-0.70.9-0.50.3-0.3-0.00.10.10.1-0.0-0.30.1-0.11.0
Total resting periods, locomotor time 20.30.51.7-1.31.20.2-1.00.80.9-0.51.3-0.30.60.10.30.50.50.4-0.3-0.00.40.30.9
Rest time, locomotor task time 21.21.62.9-0.80.81.3-1.71.71.60.31.50.61.31.21.31.51.51.5-1.01.01.41.4-0.2
Distance moved, locomotor task time 21.72.02.90.00.0-1.61.7-1.7-1.7-1.0-1.3-1.3-1.6-1.5-1.5-1.7-1.5-1.61.5-1.3-1.4-1.60.9
Vertical activity count, locomotor time 20.20.30.50.4-0.4-0.60.7-0.6-0.5-0.2-0.4-0.4-0.7-0.4-0.5-0.5-0.5-0.60.6-0.4-0.5-0.60.2
Light reinforcement 10.10.30.60.2-0.2-0.50.8-0.7-0.6-0.2-0.7-0.3-0.5-0.6-0.6-0.6-0.6-0.60.4-0.4-0.6-0.50.3
Light reinforcement 20.40.62.1-1.21.2-0.50.7-0.3-0.6-0.7-0.8-0.6-0.6-0.5-0.6-0.6-0.6-0.60.6-0.8-0.6-0.51.5
Bone: marrow area0.81.812.0-3.53.40.20.00.3-0.2-1.9-0.1-1.4-0.8-0.2-0.3-0.1-0.1-0.01.2-0.9-0.3-0.01.9
Bone: maximum diameter0.30.53.2-1.81.70.6-0.50.70.3-0.60.3-0.3-0.10.20.40.40.50.50.3-0.00.30.40.5
Bone: maximum force4.68.29.4-2.32.4-3.03.0-2.9-2.9-2.9-2.8-3.1-3.0-3.0-2.9-2.9-2.9-2.93.0-3.0-2.9-2.82.6
Bone: maximum moment3.96.97.8-2.32.3-2.82.7-2.6-2.7-2.7-2.6-2.8-2.7-2.7-2.7-2.7-2.7-2.62.7-2.8-2.6-2.62.4
Mean time between licks in bursts0.61.63.1-0.90.91.6-1.51.81.40.61.21.01.21.51.31.51.31.4-1.10.91.31.40.0
Mean num. licks in bursts0.40.61.41.2-1.2-1.10.8-0.9-0.60.3-0.60.0-0.1-1.1-0.8-0.8-0.9-0.8-0.1-0.4-0.7-0.9-0.3
Cd content in liver0.10.10.60.8-0.7-0.30.1-0.3-0.10.3-0.40.00.1-0.0-0.1-0.0-0.1-0.2-0.10.10.1-0.00.4
Co content in liver1.31.52.60.00.0-1.51.3-1.6-1.3-0.9-1.4-1.2-1.3-1.4-1.3-1.3-1.3-1.41.2-1.1-1.3-1.30.8
Cu content in liver1.31.55.42.3-2.30.8-0.60.40.81.80.71.71.10.70.80.70.70.7-1.41.10.80.6-2.0
Fe content in liver1.01.21.9-0.10.1-1.31.2-1.4-1.2-0.7-1.1-1.0-1.0-1.3-1.2-1.2-1.3-1.30.9-1.1-1.2-1.30.7
K content in liver0.10.11.30.6-0.60.1-0.1-0.00.20.40.20.40.1-0.10.10.00.00.0-0.20.2-0.1-0.1-1.2
Mg content in liver1.51.52.50.4-0.41.5-1.31.31.41.01.21.21.21.31.41.31.41.4-1.11.31.21.2-1.6
Mn content in liver4.04.47.10.1-0.12.7-2.32.62.41.42.61.92.02.32.32.32.32.4-1.82.02.12.3-1.8
Na content in liver0.70.71.40.1-0.1-0.90.9-1.2-0.9-0.6-0.8-0.7-0.9-1.0-0.9-1.0-1.0-1.00.8-0.8-1.1-1.0-0.1
Rb content in liver1.11.33.51.2-1.21.1-0.91.01.11.40.81.31.21.01.01.01.01.0-1.31.11.00.9-1.9
Se content in liver1.21.42.6-0.80.71.6-1.51.61.40.21.60.60.91.31.41.41.51.4-0.71.01.31.4-0.4
Sr content in liver0.30.31.0-1.01.0-0.40.4-0.3-0.4-0.7-0.3-0.7-0.7-0.3-0.4-0.4-0.3-0.30.7-0.5-0.4-0.30.6
Zn content in liver0.10.10.2-0.0-0.00.3-0.40.40.40.30.30.30.40.20.30.40.40.4-0.30.30.30.3-0.5
Bone: minimum diameter0.30.63.9-2.01.90.6-0.50.80.4-0.70.5-0.4-0.00.30.40.50.50.50.3-0.10.30.50.9
Time in familiar zone, hab. session 11.71.66.22.5-2.50.5-0.80.60.81.80.61.41.30.70.90.80.80.8-1.41.20.90.7-1.5
Time in novel zone, hab. session 10.70.73.7-1.91.9-0.20.4-0.3-0.4-1.4-0.2-1.0-0.8-0.3-0.5-0.4-0.4-0.40.9-0.8-0.5-0.31.0
Total zone transitions, hab. session 10.60.81.21.0-1.00.9-0.80.80.81.10.91.10.90.90.80.80.80.8-1.00.90.80.8-1.1
Total locomotion distance, hab. session 10.30.40.90.9-0.90.5-0.50.50.50.70.50.60.60.60.60.50.60.5-0.60.70.60.5-0.7
Locomotion velocity, hab. session 10.10.10.50.7-0.70.1-0.10.10.10.40.10.20.20.20.20.10.20.1-0.20.30.20.1-0.4
Time in familiar zone, hab. session 20.10.10.70.9-0.9-0.1-0.1-0.00.00.5-0.20.40.20.10.10.10.00.1-0.30.20.10.1-0.4
Time in novel zone, hab. session 20.20.20.4-0.60.6-0.30.3-0.4-0.3-0.5-0.2-0.5-0.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.40.4
Total zone transitions, hab. session 20.00.10.10.3-0.2-0.20.2-0.3-0.2-0.2-0.1-0.4-0.3-0.2-0.1-0.2-0.1-0.30.3-0.1-0.2-0.20.3
Total locomotion distance, hab. session 20.60.71.71.3-1.30.7-0.70.60.80.90.80.70.70.70.90.80.80.7-0.71.00.80.7-0.9
Locomotion velocity, hab. session 20.60.91.71.3-1.30.8-0.80.70.90.90.90.70.80.81.00.91.00.8-0.81.00.90.8-0.9
Novel to familiar place preference ratio0.10.10.20.2-0.2-0.10.4-0.4-0.3-0.0-0.3-0.0-0.3-0.4-0.2-0.4-0.3-0.30.2-0.1-0.3-0.3-0.3
Novelty place preference0.10.20.3-0.10.1-0.30.5-0.5-0.5-0.3-0.4-0.3-0.4-0.5-0.4-0.5-0.4-0.40.4-0.3-0.4-0.5-0.0
Time in novel zone, NPP test0.20.20.4-0.30.3-0.40.6-0.5-0.5-0.5-0.5-0.4-0.5-0.6-0.5-0.6-0.5-0.50.5-0.5-0.5-0.60.2
Total zone transitions, NPP test1.01.41.71.2-1.21.2-1.11.11.21.31.21.31.31.21.21.21.21.1-1.31.21.11.1-1.1
Total locomotion distance, NPP test0.60.82.11.5-1.50.6-0.70.60.81.10.70.90.90.70.80.70.80.7-0.91.00.80.7-1.1
Locomotion velocity, NPP test1.21.73.71.9-1.91.0-1.00.91.11.61.11.41.31.11.21.11.11.1-1.31.41.21.0-1.5
Intraocular pressure0.81.11.91.2-1.20.7-1.00.90.91.31.01.21.30.90.91.00.80.9-1.41.01.01.0-1.0
Delta distance traveled before/after self-admin2.32.43.8-1.21.3-1.71.4-1.6-1.9-1.6-1.6-1.7-2.0-1.4-1.5-1.4-1.5-1.51.9-1.5-1.5-1.41.0
Delta ambulatory time before/after self-admin1.41.73.1-1.31.3-1.41.0-1.2-1.5-1.5-1.5-1.6-1.7-1.2-1.1-1.0-1.1-1.11.8-1.2-1.2-1.11.1
Parametrial fat weight1.02.34.3-1.21.2-1.62.1-1.6-1.6-1.1-1.4-1.1-1.3-2.0-1.7-1.8-1.7-1.51.1-1.6-1.6-1.70.4
Pavlov. Cond. lever latency2.02.54.10.5-0.5-2.01.9-2.0-1.8-1.0-1.9-1.3-1.5-1.9-1.7-1.8-1.7-1.81.4-1.3-1.6-1.80.6
Pavlov. Cond. magazine entry latency2.73.55.20.1-0.12.2-2.12.32.11.42.31.51.92.22.02.12.12.1-1.71.72.02.1-0.9
Pavlov. Cond. change in total contacts0.20.31.8-1.31.30.4-0.30.50.3-0.50.4-0.2-0.00.30.10.20.20.20.2-0.20.10.20.6
Pavlov. Cond. index score3.13.96.1-0.20.22.4-2.32.52.31.42.51.61.92.32.12.32.22.2-1.81.82.12.3-0.8
Pavlov. Cond. latency score2.43.04.9-0.50.42.2-2.12.22.01.12.21.31.62.01.92.01.92.0-1.51.51.82.0-0.6
Pavlov. Cond. lever contacts1.61.93.4-0.70.61.8-1.71.81.60.71.71.01.21.61.51.61.61.6-1.11.11.41.6-0.4
Pavlov. Cond. magazine entry number3.44.36.1-0.60.6-2.32.3-2.4-2.4-1.7-2.5-1.8-2.1-2.3-2.2-2.3-2.3-2.31.9-2.0-2.2-2.31.3
Pavlov. Cond. intertrial magazine entries0.30.42.21.5-1.5-0.40.4-0.6-0.30.8-0.40.50.2-0.2-0.3-0.3-0.4-0.4-0.40.1-0.2-0.3-0.8
Pavlov. Cond. lever-magazine prob. diff.3.54.36.5-0.0-0.02.5-2.42.52.41.52.51.82.12.42.22.32.32.3-1.91.92.22.4-1.0
Pavlov. Cond. response bias3.64.56.70.2-0.22.5-2.42.62.41.72.61.82.12.42.32.42.32.4-2.02.02.32.4-1.1
Pavlov. Cond. lever latency0.20.30.8-0.90.9-0.30.4-0.4-0.5-0.8-0.5-0.5-0.5-0.6-0.4-0.4-0.4-0.40.5-0.5-0.5-0.50.5
Pavlov. Cond. magazine entry latency0.20.20.8-0.90.9-0.30.4-0.2-0.4-0.6-0.3-0.6-0.5-0.2-0.4-0.4-0.3-0.30.5-0.5-0.4-0.30.6
Pavlov. Cond. change in total contacts0.20.20.4-0.30.3-0.50.6-0.5-0.5-0.5-0.4-0.6-0.6-0.3-0.5-0.6-0.5-0.60.6-0.5-0.5-0.50.4
Pavlov. Cond. index score0.00.00.1-0.10.10.1-0.00.20.10.10.1-0.00.00.30.10.10.10.1-0.00.00.10.20.2
Pavlov. Cond. latency score0.00.00.1-0.20.2-0.20.3-0.1-0.2-0.2-0.1-0.3-0.20.1-0.2-0.2-0.2-0.20.2-0.2-0.2-0.10.3
Pavlov. Cond. lever contacts0.10.10.40.6-0.60.1-0.20.20.30.50.30.20.30.40.20.20.20.2-0.30.30.20.3-0.2
Pavlov. Cond. magazine entry number0.20.30.60.6-0.60.5-0.60.40.50.60.40.70.60.30.50.50.40.5-0.60.60.40.3-0.8
Pavlov. Cond. intertrial magazine entries1.82.64.00.5-0.52.0-1.81.91.71.51.61.71.71.91.71.81.71.8-1.71.61.71.8-1.2
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.10.10.1-0.10.20.10.10.20.00.10.40.10.10.10.1-0.10.10.10.30.1
Pavlov. Cond. response bias0.20.20.50.2-0.30.4-0.50.60.50.50.60.40.50.70.50.50.50.5-0.50.50.50.6-0.2
Time in closed arm before self-admin0.10.10.50.2-0.20.30.00.30.5-0.20.40.30.30.10.30.10.40.3-0.20.30.30.2-0.7
Time in closed arm after self-admin1.11.11.9-0.40.4-1.01.3-1.3-0.9-1.0-1.0-1.2-1.1-1.4-1.1-1.1-1.1-1.21.1-1.0-1.3-1.30.5
Time in open arm before self-admin0.60.61.40.3-0.30.8-1.20.80.70.70.60.80.81.00.81.00.80.8-0.80.80.80.9-0.4
Time in open arm after self-admin0.40.51.0-0.0-0.00.6-0.60.90.40.60.80.70.71.00.70.70.70.8-0.70.60.90.90.1
Bone: periosteal estimation1.22.69.6-3.13.1-0.80.9-0.7-1.1-2.2-1.0-1.9-1.5-1.1-1.1-1.0-1.0-0.91.7-1.5-1.1-1.02.2
Bone: periosteal perimeter0.30.53.8-1.91.90.00.00.2-0.1-1.0-0.1-0.7-0.5-0.2-0.2-0.1-0.1-0.00.6-0.5-0.2-0.11.0
Bone: post-yield work1.01.52.9-0.80.71.5-1.51.71.50.71.50.81.21.41.31.41.31.4-1.00.91.31.4-0.3
Progressive ratio test 1 active lever presses0.30.42.40.2-0.2-0.41.0-0.4-1.10.1-1.5-0.2-0.6-0.3-0.4-0.7-0.5-0.50.5-0.3-0.3-0.40.3
Progressive ratio test 1 breakpoint0.30.42.50.2-0.2-0.51.1-0.5-1.10.0-1.6-0.3-0.7-0.4-0.5-0.7-0.5-0.50.6-0.3-0.3-0.40.3
Progressive ratio test 1 inactive lever presses0.30.51.10.6-0.6-0.60.8-0.9-1.00.1-1.0-0.3-0.8-0.7-0.7-0.9-0.7-0.80.6-0.4-0.6-0.7-0.1
Progressive ratio test 2 active lever presses0.10.20.80.8-0.80.20.40.0-0.30.9-0.50.50.00.30.10.00.00.0-0.20.20.20.1-0.2
Progressive ratio test 2 breakpoint0.10.20.70.8-0.80.10.4-0.0-0.30.9-0.50.5-0.00.2-0.0-0.1-0.1-0.0-0.20.20.10.0-0.2
Progressive ratio test 2 inactive lever presses0.30.51.3-0.60.6-0.41.1-0.5-1.0-0.1-1.1-0.7-0.9-0.5-0.6-0.7-0.6-0.50.9-0.6-0.5-0.50.6
Incentive Sensitization - Responses0.40.50.90.9-0.90.7-0.70.60.60.90.60.80.60.90.70.80.70.7-0.60.80.80.8-0.6
Incentive Sensitization - Breakpoint0.40.61.01.0-1.00.7-0.70.50.61.00.60.90.60.80.70.80.70.7-0.70.80.70.7-0.6
Sum of active levers in priming session hrs 5-60.40.40.80.5-0.50.4-0.60.40.6-0.10.40.50.70.80.70.90.70.7-0.60.70.80.9-0.1
Progressive ratio5.38.310.1-2.22.3-3.03.2-2.9-3.1-3.0-2.9-3.1-3.1-2.8-3.0-3.0-2.9-2.93.1-3.0-2.7-2.62.6
Food seeking constrained by brief footshock0.10.10.50.3-0.30.0-0.3-0.00.20.20.20.30.20.20.10.10.10.2-0.30.20.20.2-0.7
Seeking ratio, punishment vs. effort4.66.79.22.1-2.12.6-3.02.52.82.62.62.72.72.42.72.72.62.6-2.62.72.42.3-2.6
Retroperitoneal fat weight0.41.83.4-1.01.0-1.51.8-1.3-1.5-1.1-1.2-1.1-1.3-1.4-1.5-1.5-1.5-1.41.2-1.5-1.4-1.40.8
Reaction time number correct0.40.91.60.5-0.5-1.20.7-1.3-0.9-0.6-1.2-0.7-0.8-1.2-1.0-1.0-1.0-1.10.7-0.8-1.0-1.20.2
Reaction time mean minus median0.92.14.2-1.11.11.7-1.62.01.60.81.71.31.51.81.31.71.41.6-1.50.91.51.80.0
Reaction time mean minus median AUC0.71.93.5-0.70.61.5-1.71.91.50.91.81.21.41.61.31.61.41.5-1.31.01.41.6-0.0
Reaction time num false alarms0.30.41.2-0.90.9-0.30.7-0.3-0.4-0.9-0.2-0.7-0.7-0.5-0.4-0.6-0.4-0.50.7-0.6-0.5-0.41.1
Reaction time num false alarms AUC0.50.71.6-1.21.2-0.40.9-0.5-0.7-1.2-0.5-0.9-1.0-0.7-0.6-0.8-0.5-0.71.1-0.8-0.7-0.61.3
Reaction time trials correct on left0.40.91.60.5-0.5-1.20.7-1.3-0.9-0.6-1.2-0.7-0.8-1.2-1.0-1.0-1.0-1.10.7-0.8-1.0-1.20.2
Reaction time trials on left0.40.81.60.4-0.4-1.20.7-1.2-0.9-0.7-1.2-0.7-0.8-1.2-1.0-1.0-1.0-1.10.7-0.8-0.9-1.10.3
Reaction time mean2.03.15.4-0.80.72.2-2.02.31.91.12.21.71.82.11.82.01.92.0-1.71.41.82.1-0.4
Reaction time mean AUC2.03.25.4-0.80.72.2-2.02.32.01.12.21.61.82.21.82.11.92.0-1.71.41.82.1-0.3
Median of all reaction times1.52.23.7-0.60.51.9-1.61.91.60.91.91.41.51.71.51.71.61.6-1.41.21.41.7-0.4
Reaction time omissions1.11.63.3-0.80.81.6-1.41.81.30.51.21.11.41.41.31.51.41.5-1.31.01.41.50.0
Reaction time false alarm rate0.20.31.7-1.31.30.30.30.3-0.0-0.70.2-0.4-0.40.20.1-0.10.20.10.5-0.2-0.00.21.0
Reaction time premature initiation rate1.72.43.6-1.31.3-1.41.4-1.5-1.7-1.5-1.5-1.5-1.9-1.7-1.5-1.6-1.4-1.51.9-1.5-1.5-1.71.1
Reaction time premature initiations2.24.05.8-1.01.1-2.11.9-2.2-2.2-1.8-2.1-2.0-2.3-2.4-2.0-2.1-2.0-2.12.3-1.9-2.0-2.31.3
Std. dev. reaction times1.11.93.9-1.41.41.7-1.52.01.40.41.61.11.21.71.31.61.41.6-1.10.81.41.70.4
Reaction time trials completed0.40.81.60.4-0.4-1.20.7-1.2-0.9-0.7-1.2-0.7-0.8-1.2-1.0-1.0-1.0-1.10.7-0.8-0.9-1.10.3
Reaction time trials AUC0.40.71.50.5-0.5-1.10.6-1.2-0.8-0.6-1.1-0.7-0.7-1.2-0.9-0.9-0.9-1.00.6-0.7-0.9-1.10.2
Run reversals in cocaine runway, females0.20.20.80.6-0.5-0.50.7-0.8-0.70.1-0.9-0.0-0.4-0.3-0.5-0.4-0.5-0.40.2-0.2-0.5-0.4-0.2
Run reversals in cocaine runway, males0.50.53.3-1.81.80.1-0.20.3-0.3-0.5-0.1-0.4-0.2-0.1-0.20.0-0.20.00.3-0.5-0.00.11.3
Latency to leave start box in cocaine runway0.10.10.30.2-0.20.2-0.40.40.60.10.5-0.40.2-0.10.40.50.40.30.00.40.30.2-0.4
Latency to leave start box in cocaine runway, F0.50.61.20.5-0.50.6-1.00.81.10.40.90.30.80.40.90.90.90.8-0.60.80.70.6-1.0
Latency to leave start box in cocaine runway, M0.80.81.7-0.70.8-0.91.0-0.8-0.8-0.7-0.6-1.3-1.0-1.0-0.8-0.8-0.8-0.81.1-0.8-0.9-0.80.8
Std. dev. time between licks in bursts0.71.01.8-1.31.31.3-1.21.31.0-0.20.90.20.61.11.01.11.11.1-0.30.60.91.10.3
Total sessions with >9 infusions0.50.61.7-0.30.3-0.71.3-0.8-1.1-0.1-1.1-0.6-0.9-0.6-0.9-1.0-0.9-0.80.8-0.7-0.7-0.70.6
Short access day 1 total inactive lever presses1.31.74.8-2.22.2-0.60.8-0.8-1.1-1.2-0.7-1.4-1.4-1.1-1.1-1.0-1.1-1.01.4-1.4-1.2-1.01.9
Short access day 10 total inactive lever presses0.10.30.80.3-0.30.8-0.90.50.50.90.40.60.30.40.60.60.50.6-0.40.50.40.3-0.4
Short access day 1 total infusions0.00.00.40.2-0.20.00.6-0.1-0.20.3-0.2-0.1-0.10.1-0.1-0.2-0.1-0.10.1-0.0-0.00.10.2
Short access day 10 total infusions0.40.51.3-0.10.1-0.51.2-0.9-1.00.2-1.1-0.3-0.7-0.3-0.8-0.9-0.8-0.70.6-0.6-0.7-0.50.3
Short access total infusions0.70.92.7-0.30.3-0.71.6-0.9-1.4-0.0-1.5-0.7-0.9-0.6-1.0-1.1-1.0-0.90.9-0.9-0.9-0.80.8
Short access day 1 locomotion1.21.53.51.3-1.31.3-0.81.10.91.91.01.41.01.41.21.11.11.2-1.11.31.21.3-1.1
Short access day 10 total locomotion0.10.21.3-1.11.10.10.3-0.10.1-0.70.5-0.5-0.3-0.1-0.1-0.2-0.0-0.10.4-0.3-0.2-0.10.6
Short access total locomotion0.00.00.2-0.30.30.50.30.1-0.10.2-0.10.2-0.10.30.2-0.00.20.20.10.10.10.2-0.0
One hour access (0.3 mA shock)1.11.32.71.4-1.41.1-0.61.00.71.60.11.40.91.21.11.01.11.2-1.11.31.31.1-1.4
Compulsive drug intake4.25.06.81.4-1.42.5-2.62.42.22.02.12.22.22.22.52.42.52.5-2.12.42.42.3-1.8
One hour access (shock baseline)0.50.72.1-0.10.2-1.01.5-0.8-1.1-0.3-1.4-0.4-0.8-0.8-1.0-0.9-1.0-0.80.6-0.8-0.7-0.70.4
Social response proportion0.10.10.5-0.70.70.1-0.20.2-0.0-0.40.2-0.4-0.20.20.10.10.20.10.4-0.10.00.10.7
Social responses0.30.40.9-0.80.8-0.50.4-0.5-0.5-1.0-0.4-0.9-0.8-0.4-0.4-0.5-0.4-0.50.9-0.5-0.5-0.50.8
Social time0.70.92.0-1.41.41.1-1.11.41.1-0.21.20.20.61.01.01.01.11.1-0.30.60.91.00.2
Soleus weight0.41.25.8-2.42.41.2-0.81.30.7-0.90.9-0.40.10.80.90.81.11.10.30.30.80.90.4
Bone: stiffness1.01.62.3-0.60.6-1.51.4-1.4-1.3-1.0-1.3-1.2-1.2-1.4-1.4-1.4-1.4-1.41.1-1.3-1.3-1.31.1
Tibialis anterior weight0.20.81.60.6-0.6-1.11.2-1.2-1.0-0.2-1.0-0.4-0.7-1.2-1.0-1.1-1.1-1.00.5-0.7-1.0-1.1-0.5
Time to tail flick, vehicle, before self-admin1.41.52.80.8-0.81.2-1.21.21.41.11.61.31.21.01.11.01.21.2-1.21.21.31.1-1.7
Time to tail flick, vehicle, after self-admin0.91.22.80.2-0.31.2-0.91.31.30.81.70.91.11.21.21.21.21.3-1.01.11.21.2-1.1
Time to tail flick, test, before self-admin0.10.10.70.3-0.30.1-0.00.10.10.30.00.50.10.20.10.10.10.2-0.30.20.20.3-0.8
Time to tail flick, test, after self-admin0.90.91.80.4-0.40.9-1.01.01.20.81.31.31.20.90.81.00.80.9-1.30.70.81.0-0.6
Delta time to tail flick, vehicle, before/after SA0.00.00.10.4-0.4-0.00.20.1-0.00.30.2-0.00.1-0.00.00.20.00.0-0.10.10.00.00.0
Delta time to tail flick, test, before/after SA0.30.30.90.8-0.80.4-0.60.40.70.60.90.70.80.30.40.60.40.3-0.80.50.40.3-0.2
Tibia length1.33.512.0-3.53.4-1.21.3-1.0-1.3-2.6-1.0-2.3-1.7-1.2-1.4-1.3-1.3-1.22.0-1.9-1.4-1.22.5
Ambulatory time before self-admin0.10.10.4-0.60.60.30.30.10.1-0.00.20.10.20.1-0.1-0.2-0.1-0.0-0.2-0.2-0.0-0.10.6
Ambulatory time after self-admin1.11.32.7-1.61.6-1.10.9-0.8-1.3-1.5-1.2-1.3-1.2-0.9-1.0-0.9-0.9-0.81.3-1.1-0.9-0.81.1
Bone: tissue strength4.44.55.2-1.81.8-2.22.1-2.1-2.3-2.1-2.2-2.1-2.2-2.1-2.2-2.2-2.2-2.12.2-2.2-2.2-2.11.6
Total heroin consumption0.00.10.3-0.40.30.1-0.20.2-0.2-0.1-0.60.10.20.20.10.20.20.2-0.10.10.20.20.2
Bone: trabecular number0.81.34.32.1-2.10.6-0.60.50.71.70.81.51.10.70.70.70.60.7-1.31.00.80.7-1.7
Bone: trabecular spacing2.73.67.2-2.72.7-1.51.5-1.4-1.7-2.3-1.7-2.2-2.0-1.5-1.6-1.6-1.6-1.62.1-1.9-1.7-1.52.2
Bone: trabecular thickness0.81.02.71.6-1.60.6-0.70.60.81.40.81.41.20.70.70.80.70.7-1.30.90.80.7-0.9
Bone: trabecular tissue density1.82.64.2-1.41.4-1.71.5-1.5-1.5-2.0-1.4-2.0-1.7-1.6-1.5-1.5-1.4-1.51.8-1.6-1.5-1.52.0
Water consumed over 24 hours0.00.00.1-0.30.3-0.1-0.00.10.1-0.30.3-0.3-0.2-0.10.10.00.10.10.30.00.1-0.0-0.3
Number of responses in last shaping day0.60.71.7-1.11.1-0.41.0-0.4-0.8-1.1-0.7-1.3-1.0-0.5-0.5-0.6-0.4-0.61.2-0.6-0.6-0.41.3