Hub : Genes

LOC102548513

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression LOC102548513 0.04 0.03 7.7e-04 0.03 0.03 0.03 0.03 6.8e-04 4.6e-04 6.2e-04 2.1e-03
2 LHb gene expression LOC102548513 0.17 0.1 6.8e-04 0.16 0.13 0.1 0.11 1.1e-04 6.9e-04 1.8e-03 1.4e-03
3 IL gene expression LOC102548513 0.33 0.14 4.4e-07 0.16 0.17 0.17 0.17 1.4e-04 5.5e-05 5.5e-05 8.0e-05
4 OFC gene expression LOC102548513 0.14 0.09 3.2e-03 0.05 0.04 0.01 0.04 2.3e-02 3.3e-02 1.4e-01 4.9e-02
5 PL gene expression LOC102548513 0.04 0.03 2.7e-05 0.03 0.04 0.04 0.03 3.7e-04 3.0e-05 6.9e-05 1.2e-04
6 NAcc gene expression LOC102548513 0.03 0.02 2.6e-04 0.03 0.03 0.04 0.03 2.6e-04 1.1e-04 3.7e-05 7.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density1.01.63.7-1.01.9-1.91.10.3-0.4
Area under the delay curve0.20.20.70.5-0.40.3-0.10.10.8
BMI with tail4.815.523.3-4.84.2-4.64.2-3.21.8
BMI without tail4.59.413.9-3.72.7-3.13.4-3.31.6
Body weight7.029.244.2-6.66.0-6.25.7-4.12.6
Weight adjusted by age0.50.61.1-0.80.8-1.00.6-0.10.9
Bone surface0.61.12.6-0.91.2-1.61.1-0.5-0.4
Bone volume0.91.53.2-1.11.6-1.81.3-0.4-0.7
Breakpoint value in progressive ratio session0.40.50.8-0.80.9-0.80.9-0.20.1
Number of licking bursts0.20.20.4-0.50.6-0.50.40.0-0.2
Context. condit. distance diff. score0.10.10.30.3-0.10.3-0.30.50.5
Locomotion velocity, session 10.40.41.00.7-0.70.7-0.40.2-1.0
Locomotion distance, session 11.21.53.01.5-1.71.2-1.10.3-1.0
Locomotion velocity, session 21.82.13.51.9-1.51.5-1.51.50.5
Locomotion distance, session 22.13.05.22.3-2.11.9-1.71.3-0.4
Locomotion velocity, session 30.20.20.40.5-0.50.5-0.2-0.1-0.6
Locomotion distance, session 30.00.00.20.00.2-0.10.10.10.4
Stereotopy head waving bouts, day 30.70.81.3-1.00.9-1.10.9-0.8-0.3
Stereotopy head waving duration, day 30.20.30.5-0.60.3-0.50.6-0.7-0.2
Locomotion velocity, session 71.21.31.91.3-1.01.2-1.41.4-0.2
Locomotion distance, session 70.10.10.3-0.30.5-0.40.20.10.2
Stereotopy head waving bouts, day 70.10.10.5-0.3-0.0-0.10.4-0.7-0.2
Stereotopy head waving duration, day 70.30.31.0-0.4-0.0-0.30.7-1.0-0.4
Locomotion velocity, session 81.51.72.81.7-1.41.5-1.21.2-0.8
Locomotion distance, session 81.21.83.11.8-1.51.5-1.41.20.1
Degree of sensitization distance0.00.00.1-0.20.2-0.30.1-0.00.0
Degree of sensitization stereotypy0.00.00.1-0.0-0.00.10.2-0.20.3
Conditioned locomotion1.61.92.9-1.71.7-1.61.4-1.00.3
Cocaine response after cond. corrected1.31.52.41.2-0.51.0-1.31.51.5
Cocaine response after cond. not corrected1.01.12.01.1-0.50.9-1.21.41.0
Cocaine response before conditioning0.20.21.2-0.1-0.0-0.30.2-0.2-1.1
Saline control response0.40.52.1-0.50.4-0.60.4-0.2-1.5
Bone: connectivity density0.81.22.7-0.41.6-1.70.60.90.9
Bone: cortical apparent density0.50.71.5-1.20.6-0.40.8-1.2-0.0
Bone: cortical area2.43.76.7-2.62.4-2.11.9-1.10.4
Bone: cortical porosity1.31.43.6-0.71.9-1.50.90.71.0
Bone: cortical porosity1.51.74.2-0.82.1-1.60.80.91.1
Bone: cortical thickness4.37.113.2-3.53.6-2.82.6-1.30.9
Bone: cortical thickness1.21.43.1-1.41.8-1.30.90.11.0
Bone: cortical tissue density0.40.61.4-1.10.4-0.30.7-1.2-0.1
Condit. Reinf. active minus inactive responses1.21.32.2-1.31.4-1.51.3-0.70.2
Condit. Reinf. active-inactive response ratio0.50.51.2-0.41.1-0.80.40.60.7
Condit. Reinf. active responses0.40.40.7-0.70.4-0.60.7-0.8-0.7
Condit. Reinf. inactive responses0.60.82.50.1-0.90.40.1-1.0-1.6
Incentive salience index mean0.10.20.4-0.20.1-0.40.4-0.5-0.7
Condit. Reinf. lever presses0.70.92.10.9-1.41.0-0.7-0.3-1.0
Condit. Reinf. active minus inactive responses0.30.41.10.4-0.80.6-0.5-0.0-1.0
Condit. Reinf. active-inactive response ratio0.30.30.60.6-0.80.6-0.60.30.5
Condit. Reinf. active responses0.30.51.10.2-0.90.6-0.3-0.6-1.1
Condit. Reinf. inactive responses0.60.71.8-0.5-0.50.10.4-1.3-1.3
Condit. Reinf. lever presses0.91.25.00.0-0.90.20.3-1.2-2.2
Condit. Reinf. lever reinforcers received0.50.71.40.3-1.20.7-0.4-0.6-1.2
Conditioned reinforcement - actives2.22.25.01.7-0.70.9-1.42.2-1.4
Conditioned reinforcement - inactives0.50.51.00.7-0.80.8-0.60.2-1.0
Conditioned locomotion2.42.94.72.0-1.31.4-1.92.2-1.1
Patch foraging indifference point 0 sec1.52.511.10.7-1.40.9-0.5-0.3-3.3
Patch foraging indifference point AUC4.95.610.72.4-3.33.1-2.60.8-0.4
Delay disc. indifference point, 0s delay0.40.42.40.10.1-0.2-0.00.21.5
Delay disc. indifference point, 16s delay0.70.71.41.2-1.00.9-0.80.70.4
Delay disc. indifference point, 2s delay0.30.40.90.7-0.70.3-0.40.31.0
Delay disc. indifference point, 24s delay0.20.21.0-0.3-0.2-0.10.4-1.00.0
Delay disc. indifference point, 4s delay0.20.21.10.4-0.10.0-0.10.51.1
Delay disc. indifference point, 8s delay0.20.20.90.10.00.10.3-0.20.9
Indifference point function ln k3.34.68.3-2.32.9-2.82.3-0.80.2
Indifference point function log k3.34.68.3-2.32.9-2.82.3-0.80.2
Patch foraging total patch changes 0 sec2.03.212.70.9-1.81.3-0.7-0.3-3.6
Patch foraging total patch changes 12 sec1.21.53.60.7-1.91.3-0.6-0.8-1.5
Patch foraging total patch changes 18 sec6.88.715.22.8-3.93.4-2.60.5-3.3
Patch foraging total patch changes 24 sec4.75.710.12.4-3.22.7-2.10.5-2.5
Patch foraging total patch changes 6 sec3.14.614.81.2-2.52.0-1.1-0.6-3.8
Patch foraging time to switch 0 sec2.53.95.5-2.22.3-2.32.3-1.50.5
Patch foraging water rate 0 sec3.14.97.92.3-2.82.8-2.51.1-1.1
Patch foraging water rate 12 sec1.11.72.11.4-1.21.4-1.31.3-1.1
Patch foraging water rate 18 sec0.50.70.90.9-0.71.0-1.00.9-0.5
Patch foraging water rate 24 sec1.72.43.71.6-1.51.9-1.91.4-0.3
Patch foraging water rate 6 sec0.50.71.80.6-0.10.7-1.01.40.6
Seeking ratio, delayed vs. immediate footshock1.21.42.6-0.81.6-1.40.90.61.3
Distance traveled before self-admin0.70.81.21.1-0.90.9-1.10.70.4
Distance traveled after self-admin0.20.20.40.2-0.10.6-0.60.5-0.2
Extensor digitorum longus weight0.41.42.6-1.30.8-1.01.5-1.60.5
Bone: elastic displacement0.20.20.6-0.50.8-0.30.40.10.1
Bone: elastic work3.54.56.9-2.62.3-2.22.4-1.90.9
Bone: endosteal estimation0.10.30.7-0.3-0.0-0.90.6-0.7-0.2
Bone: endosteal perimeter0.00.10.10.3-0.3-0.3-0.20.0-0.2
Epididymis fat weight5.512.719.9-4.34.3-4.53.7-2.21.3
Delta time in closed arm before/after self-admin0.20.20.40.4-0.60.6-0.3-0.0-0.6
Delta time in open arm before/after self-admin1.61.52.4-1.61.2-1.31.3-1.20.8
Diff in mean of infusions in LGA sessions0.20.31.40.1-0.20.10.2-0.1-1.2
Delay discount exponential model param0.20.20.6-0.40.4-0.3-0.0-0.0-0.8
Extinction: sum of active levers before priming0.10.10.40.1-0.20.2-0.20.10.6
Active lever presses in extinction session 61.81.72.5-1.61.5-1.51.4-1.00.4
Bone: final force2.43.86.8-2.62.2-2.12.1-1.60.2
Bone: final moment2.74.37.2-2.72.4-2.32.3-1.60.1
Food consumed during 24 hour testing period5.36.49.3-2.62.3-3.03.0-2.6-0.9
Glucose0.91.42.2-1.11.5-1.41.0-0.41.3
Heart weight2.02.84.2-2.12.0-2.01.7-1.10.4
Delay discount hyperbolic model param0.20.31.0-0.50.4-0.30.1-0.2-1.0
Intermittent access intake day 1-15 change1.31.32.7-0.61.4-1.40.90.11.6
Intermittent access intake escalation1.11.12.4-0.51.3-1.30.80.11.6
Intermittent access intake escalation 21.81.84.2-0.91.2-1.51.2-0.72.0
Intermitt. access day 1 inactive lever presses0.30.41.00.5-0.60.6-0.40.2-1.0
Intermitt. access day 15 inactive lever presses1.92.03.4-1.71.6-1.81.5-1.20.3
Intermitt. access escalation Index2.52.25.3-1.41.1-1.21.3-1.22.3
Intermittent access day 1 total infusions0.91.11.8-1.01.3-1.10.90.1-1.2
Intermittent access day 15 total infusions1.92.14.5-1.32.1-2.01.5-0.0-0.3
Intermittent access terminal intake (last 3 days)1.82.04.1-1.42.0-1.91.5-0.3-0.4
Intermittent access total infusions2.12.43.4-1.51.8-1.71.7-0.8-1.5
Intermittent access day 1 locomotion1.61.79.5-0.30.4-0.30.5-0.1-3.1
Intermittent access day 15 total locomotion0.40.41.20.10.3-0.5-0.10.9-1.1
Intermittent access total locomotion0.80.95.40.00.2-0.10.10.1-2.3
Intermittent access standard deviation0.40.41.00.21.0-0.80.40.80.4
Left kidney weight0.61.73.1-1.61.7-1.81.1-0.10.7
Right kidney weight0.71.93.4-1.81.8-1.81.3-0.40.4
Cocaine induced anxiety0.30.40.80.6-0.90.7-0.3-0.6-0.6
Post-drug Anxiety0.40.42.1-0.3-0.30.10.4-1.4-0.4
Baseline Anxiety2.02.13.5-1.91.5-1.51.6-1.30.1
Tail length1.33.85.9-2.41.7-1.82.2-2.21.1
Length with tail2.38.412.5-3.53.3-3.33.0-2.11.6
Length without tail1.43.15.5-2.02.3-2.31.7-0.60.7
Times rat made contact with spout0.60.63.10.5-0.20.2-0.40.51.7
Lifetime Intake1.41.62.4-1.21.5-1.31.4-0.5-1.6
Liver weight, left0.91.52.4-1.51.6-1.51.3-0.70.4
Liver weight, right0.61.02.2-1.21.5-1.20.70.20.8
Locomotor activity0.50.72.5-0.5-0.0-0.51.0-1.6-0.7
Locomotor testing distance0.30.52.00.3-0.70.10.1-0.7-1.4
Locomotor testing rearing1.11.72.71.7-1.51.2-1.30.9-1.1
Locomotion in novel chamber0.40.51.8-0.70.6-0.30.30.1-1.3
Locomotion in novel chamber post-restriction0.70.93.60.7-0.50.7-0.40.4-1.9
Fecal boli incidents, locomotor time 10.20.20.50.4-0.70.7-0.4-0.1-0.4
Change in fecal boli incidents, locomotor task0.80.82.6-0.60.8-0.70.6-0.21.6
Time >=10cm from walls, locomotor time 10.30.31.30.10.7-0.40.21.10.1
Bouts of movement, locomotor time 12.02.14.51.6-0.81.1-1.92.10.7
Total resting periods, locomotor time 11.81.94.11.5-0.81.1-1.82.00.3
Rest time, locomotor task time 10.20.20.3-0.30.4-0.40.6-0.5-0.2
Distance moved, locomotor task time 10.70.71.00.9-0.81.0-0.90.9-0.3
Vertical activity count, locomotor time 10.20.21.1-0.20.1-0.40.20.11.0
Time >=10cm from walls, locomotor time 22.32.44.3-1.52.1-1.92.0-0.3-0.7
Bouts of movement, locomotor time 20.80.91.41.0-0.30.9-0.91.21.1
Total resting periods, locomotor time 20.80.82.20.8-0.30.9-0.80.81.5
Rest time, locomotor task time 20.20.20.40.0-0.40.6-0.4-0.50.6
Distance moved, locomotor task time 20.70.82.30.9-0.40.3-0.51.0-1.5
Vertical activity count, locomotor time 20.20.30.8-0.2-0.1-0.40.6-0.6-0.9
Light reinforcement 10.50.91.91.2-0.70.4-1.01.4-0.7
Light reinforcement 20.20.31.20.60.2-0.0-0.31.1-0.2
Bone: marrow area0.10.20.5-0.1-0.1-0.70.4-0.6-0.1
Bone: maximum diameter0.20.40.7-0.60.8-0.80.20.40.5
Bone: maximum force2.84.98.2-2.92.2-2.32.5-2.10.1
Bone: maximum moment3.35.79.1-3.02.5-2.62.7-2.2-0.1
Mean time between licks in bursts0.10.20.5-0.20.6-0.2-0.20.70.1
Mean num. licks in bursts0.20.31.40.3-0.30.2-0.2-0.11.2
Cd content in liver2.52.75.8-1.42.4-2.21.40.21.3
Co content in liver0.81.02.51.1-0.50.6-1.11.60.6
Cu content in liver0.10.20.7-0.0-0.40.20.3-0.8-0.1
Fe content in liver0.20.31.4-0.20.0-0.40.3-0.31.2
K content in liver2.72.75.01.9-2.22.1-1.70.5-0.4
Mg content in liver0.30.40.60.6-0.70.7-0.60.20.5
Mn content in liver4.65.28.32.1-2.92.8-2.50.9-1.9
Na content in liver1.92.03.91.6-1.41.2-1.30.92.0
Rb content in liver1.31.62.7-1.71.2-1.01.3-1.50.8
Se content in liver1.31.62.6-1.61.1-1.31.3-1.30.8
Sr content in liver0.30.20.60.7-0.80.5-0.3-0.2-0.1
Zn content in liver1.11.22.6-0.41.6-1.30.51.11.2
Bone: minimum diameter1.01.92.9-1.71.3-1.61.5-1.30.6
Time in familiar zone, hab. session 10.10.10.30.0-0.1-0.10.3-0.5-0.0
Time in novel zone, hab. session 10.40.40.60.7-0.60.8-0.70.8-0.4
Total zone transitions, hab. session 10.30.40.50.7-0.70.7-0.70.50.2
Total locomotion distance, hab. session 11.92.73.92.0-1.61.7-1.81.70.5
Locomotion velocity, hab. session 11.31.82.51.6-1.21.4-1.61.50.6
Time in familiar zone, hab. session 20.60.62.7-0.1-0.0-0.20.7-0.7-1.6
Time in novel zone, hab. session 20.60.63.10.10.10.1-0.40.51.8
Total zone transitions, hab. session 20.10.10.30.5-0.60.2-0.30.10.2
Total locomotion distance, hab. session 22.02.74.52.1-1.91.6-1.91.40.2
Locomotion velocity, hab. session 22.73.65.72.4-2.11.9-2.21.70.1
Novel to familiar place preference ratio0.40.41.40.30.4-0.2-0.41.20.8
Novelty place preference0.30.30.8-0.10.6-0.4-0.10.90.5
Time in novel zone, NPP test0.30.30.5-0.20.7-0.50.10.70.6
Total zone transitions, NPP test0.81.12.21.3-1.51.2-1.00.5-0.2
Total locomotion distance, NPP test3.75.18.02.8-2.52.3-2.62.00.1
Locomotion velocity, NPP test4.46.29.53.1-2.72.6-2.92.3-0.1
Intraocular pressure0.40.51.1-0.61.0-0.90.40.30.7
Delta distance traveled before/after self-admin0.20.20.4-0.60.20.10.3-0.5-0.5
Delta ambulatory time before/after self-admin0.30.40.8-0.80.4-0.00.6-0.9-0.4
Parametrial fat weight4.79.112.6-3.52.6-2.92.9-3.32.7
Pavlov. Cond. lever latency1.11.42.3-1.41.5-1.41.1-0.60.8
Pavlov. Cond. magazine entry latency1.41.83.3-1.51.0-1.21.6-1.8-0.2
Pavlov. Cond. change in total contacts0.20.20.50.1-0.70.6-0.2-0.5-0.2
Pavlov. Cond. index score0.10.20.6-0.2-0.30.10.4-0.8-0.5
Pavlov. Cond. latency score0.20.20.50.3-0.70.5-0.1-0.4-0.7
Pavlov. Cond. lever contacts0.91.12.41.1-1.51.3-1.00.2-0.3
Pavlov. Cond. magazine entry number1.31.62.81.5-1.01.1-1.51.70.3
Pavlov. Cond. intertrial magazine entries0.20.30.40.5-0.50.6-0.60.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.2-0.20.00.5-0.9-0.4
Pavlov. Cond. response bias0.30.41.1-0.70.3-0.40.8-1.0-0.1
Pavlov. Cond. lever latency0.40.61.30.9-0.81.1-0.80.60.0
Pavlov. Cond. magazine entry latency0.50.62.1-0.50.2-0.60.6-0.8-1.4
Pavlov. Cond. change in total contacts0.00.10.20.10.0-0.0-0.30.40.1
Pavlov. Cond. index score0.40.60.8-0.80.6-0.90.7-0.7-0.9
Pavlov. Cond. latency score0.30.40.9-0.50.5-0.70.5-0.4-0.9
Pavlov. Cond. lever contacts0.40.60.8-0.80.4-0.90.7-0.9-0.7
Pavlov. Cond. magazine entry number0.50.60.80.8-0.50.7-0.70.80.9
Pavlov. Cond. intertrial magazine entries0.30.41.2-0.5-0.0-0.30.7-1.1-0.2
Pavlov. Cond. lever-magazine prob. diff.0.50.70.9-0.90.7-1.00.8-0.8-0.8
Pavlov. Cond. response bias0.70.91.3-1.00.5-0.90.9-1.1-1.1
Time in closed arm before self-admin0.30.30.4-0.60.6-0.60.7-0.6-0.2
Time in closed arm after self-admin0.20.20.9-0.20.10.00.2-0.1-1.0
Time in open arm before self-admin1.81.93.81.6-1.01.1-1.61.9-0.2
Time in open arm after self-admin0.20.20.40.3-0.20.5-0.50.60.5
Bone: periosteal estimation0.91.93.0-1.71.4-1.71.4-1.20.4
Bone: periosteal perimeter0.10.20.4-0.40.6-0.60.10.30.6
Bone: post-yield work1.21.73.2-1.41.3-1.81.4-1.1-0.3
Progressive ratio test 1 active lever presses0.70.84.30.10.30.10.10.4-2.1
Progressive ratio test 1 breakpoint0.80.95.00.10.30.10.10.3-2.2
Progressive ratio test 1 inactive lever presses0.20.20.30.5-0.20.2-0.30.6-0.5
Progressive ratio test 2 active lever presses0.50.62.70.10.5-0.30.00.6-1.6
Progressive ratio test 2 breakpoint0.60.73.4-0.20.6-0.40.20.3-1.9
Progressive ratio test 2 inactive lever presses0.20.30.50.20.6-0.70.20.7-0.5
Incentive Sensitization - Responses0.10.10.40.10.1-0.2-0.40.70.4
Incentive Sensitization - Breakpoint0.10.10.40.20.0-0.1-0.40.60.2
Sum of active levers in priming session hrs 5-60.00.00.10.0-0.30.2-0.1-0.2-0.1
Progressive ratio0.40.41.10.6-0.20.4-0.81.1-0.4
Food seeking constrained by brief footshock2.93.55.52.3-1.82.1-1.91.8-1.0
Seeking ratio, punishment vs. effort0.70.81.51.2-1.21.1-0.80.50.1
Retroperitoneal fat weight7.424.237.1-6.15.3-5.65.1-4.12.6
Reaction time number correct0.81.12.41.0-1.31.6-1.10.4-0.0
Reaction time mean minus median1.31.72.5-1.51.0-1.41.6-1.50.0
Reaction time mean minus median AUC0.30.30.5-0.60.5-0.70.7-0.5-0.2
Reaction time num false alarms0.81.13.50.90.00.4-0.91.9-1.1
Reaction time num false alarms AUC1.01.33.01.2-0.50.8-1.21.7-1.1
Reaction time trials correct on left0.81.12.41.0-1.31.6-1.10.4-0.0
Reaction time trials on left0.81.22.61.1-1.41.6-1.10.4-0.0
Reaction time mean1.01.41.8-1.21.0-1.21.3-1.2-1.0
Reaction time mean AUC1.21.62.0-1.31.1-1.31.4-1.3-1.1
Median of all reaction times0.60.81.1-0.80.7-0.90.9-0.8-1.1
Reaction time omissions0.10.10.30.4-0.30.4-0.50.40.0
Reaction time false alarm rate0.50.72.10.60.20.1-0.61.5-1.0
Reaction time premature initiation rate0.20.30.6-0.40.5-0.80.10.2-0.7
Reaction time premature initiations0.20.30.50.4-0.40.4-0.70.6-0.7
Std. dev. reaction times1.01.41.9-1.31.1-1.21.4-1.2-0.5
Reaction time trials completed0.81.22.61.1-1.41.6-1.10.4-0.0
Reaction time trials AUC0.70.92.20.9-1.31.5-1.00.20.1
Run reversals in cocaine runway, females0.90.92.9-0.70.9-0.60.8-0.51.7
Run reversals in cocaine runway, males0.30.30.60.0-0.80.7-0.2-0.80.4
Latency to leave start box in cocaine runway5.15.58.9-2.73.0-2.62.9-1.30.4
Latency to leave start box in cocaine runway, F6.77.311.0-3.13.3-3.13.3-1.7-0.2
Latency to leave start box in cocaine runway, M0.10.10.4-0.20.6-0.10.20.20.4
Std. dev. time between licks in bursts0.40.52.20.70.20.1-0.71.5-0.1
Total sessions with >9 infusions1.01.22.0-0.91.0-0.81.2-1.0-1.4
Short access day 1 total inactive lever presses1.01.12.1-1.01.2-1.31.4-0.60.4
Short access day 10 total inactive lever presses0.80.92.5-0.5-0.2-0.30.6-1.41.6
Short access day 1 total infusions0.90.93.1-0.60.6-0.51.0-0.7-1.8
Short access day 10 total infusions0.20.31.1-0.00.5-0.1-0.00.5-1.0
Short access total infusions1.01.13.1-0.81.1-0.71.0-0.3-1.8
Short access day 1 locomotion1.21.37.10.4-0.20.5-0.30.3-2.7
Short access day 10 total locomotion2.12.33.31.8-1.61.7-1.51.1-1.4
Short access total locomotion2.52.66.41.5-1.41.6-1.30.8-2.5
One hour access (0.3 mA shock)0.50.61.10.9-0.30.5-0.71.0-1.1
Compulsive drug intake1.01.01.61.0-1.11.3-0.80.4-1.1
One hour access (shock baseline)0.30.30.9-0.60.7-0.90.5-0.2-0.1
Social response proportion3.43.76.8-2.31.3-1.82.2-2.60.5
Social responses0.10.10.3-0.4-0.2-0.20.0-0.50.6
Social time1.31.88.5-0.40.8-1.00.30.42.9
Soleus weight0.31.02.70.9-0.40.5-1.31.70.5
Bone: stiffness1.32.03.8-1.91.5-1.51.4-1.20.3
Tibialis anterior weight1.13.75.0-2.21.7-2.02.2-2.20.7
Time to tail flick, vehicle, before self-admin1.01.01.8-1.31.2-0.91.2-0.70.6
Time to tail flick, vehicle, after self-admin0.00.00.1-0.1-0.0-0.2-0.1-0.1-0.3
Time to tail flick, test, before self-admin0.50.51.0-0.50.9-1.00.8-0.10.4
Time to tail flick, test, after self-admin2.93.05.2-1.51.6-2.01.7-1.02.3
Delta time to tail flick, vehicle, before/after SA0.90.91.31.1-1.00.7-1.10.7-0.9
Delta time to tail flick, test, before/after SA0.60.62.2-0.4-0.1-0.30.4-0.91.5
Tibia length5.014.221.1-4.64.5-4.34.0-2.71.5
Ambulatory time before self-admin0.60.60.90.9-0.70.7-1.00.80.8
Ambulatory time after self-admin0.10.10.30.2-0.10.6-0.40.3-0.4
Bone: tissue strength0.40.40.7-0.50.4-0.40.8-0.9-0.7
Total heroin consumption0.40.40.90.7-0.40.6-0.81.00.1
Bone: trabecular number0.81.33.0-0.51.7-1.50.61.00.8
Bone: trabecular spacing0.30.41.4-0.4-0.70.6-0.0-1.2-0.4
Bone: trabecular thickness0.70.92.2-0.81.5-1.20.60.60.3
Bone: trabecular tissue density0.10.10.50.10.20.1-0.40.7-0.2
Water consumed over 24 hours0.81.01.7-1.00.6-1.11.2-1.3-0.2
Number of responses in last shaping day0.20.20.50.30.4-0.3-0.10.7-0.7