Hub : Traits : body_g : ← →

chr2:123,236,866-125,075,599

Best TWAS P=4.644272e-10 · Best GWAS P=1.219209e-06 conditioned to 0.003040115

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Jade1	gene expression	ENSRNOG00000014066	0.13	0.01	blup	1263	0.04	4.2e-05	-3.9	5.8	5.9e-09	-0.78	0.52	0.44	FALSE
2	Brain	Jade1	alternative polyA	ENSRNOT00000018872	0.20	0.06	enet	116	0.09	1.3e-08	3.8	6.2	4.6e-10	-0.33	0.77	0.21	TRUE
3	Brain	Jade1	alternative polyA	ENSRNOT00000100298	0.20	0.06	enet	115	0.09	1.5e-08	3.8	-6.2	6.9e-10	0.25	0.76	0.21	FALSE
4	Brain	Larp1b	alternative TSS	ENSRNOT00000044804	0.06	0.03	enet	31	0.03	3.7e-04	4.1	6.1	8.8e-10	-0.51	0.34	0.54	FALSE
5	Brain	Jade1	isoform ratio	ENSRNOT00000018872	0.08	0.00	enet	39	0.01	3.0e-02	4.1	6.2	4.9e-10	-0.40	0.14	0.12	FALSE
6	Brain	Jade1	isoform ratio	ENSRNOT00000100298	0.22	0.07	enet	107	0.09	9.3e-09	3.8	-5.7	1.1e-08	0.05	0.78	0.20	FALSE
7	Brain	Larp1b	isoform ratio	ENSRNOT00000044804	0.09	0.05	enet	36	0.05	1.2e-05	4.1	6.2	6.5e-10	-0.59	0.36	0.60	FALSE
8	Brain	RGD1359508	mRNA stability	ENSRNOG00000038330	0.11	0.11	enet	99	0.12	3.5e-11	-4.4	-5.1	2.8e-07	0.90	0.43	0.56	FALSE
9	Liver	RGD1565989	gene expression	ENSRNOG00000013940	0.09	0.02	enet	37	0.02	1.1e-03	3.5	-5.4	6.3e-08	0.07	0.51	0.35	FALSE
10	PL2	Jade1	gene expression	ENSRNOG00000014066	0.35	0.03	enet	35	0.07	1.2e-04	3.9	5.6	1.7e-08	-0.25	0.24	0.08	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.