Condit. Reinf. active minus inactive responses

Pavlovian Conditioned Approach, conditioned reinforcement, active minus inactive nose-poke hole entries during the test

Tags: Behavior · Learning and memory · Pavlovian conditioned approach · Conditioned reinforcement

Project: p50_shelly_flagel_2014

3 loci · 3 genes with independent associations · 3 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr3	107934079	108540443	1	1	2.95e-10	4.46e-01	1e+00	Prr5l
2	chr9	83390749	84777604	1	1	5.98e-235	8.63e-01	1e+00	Retreg2
3	chr10	46780688	48167865	1	1	1.89e-08	2.64e-02	1e+00	Ttc19

Pleiotropic Associations

Trait	Chi² ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	Corr P	Genes
BMI with tail	291.74	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
BMI without tail	28625.59	2	1	33.3	1e+00	Prr5l Retreg2
Body weight	4.98	2	1	33.3	1e+00	Prr5l Retreg2
Epididymis fat weight	36276.19	1	1	33.3	1e+00	Retreg2
Glucose	541.77	1	1	33.3	1e+00	Retreg2
Heart weight	3065.65	1	1	33.3	1e+00	Retreg2
Left kidney weight	27525.78	2	1	33.3	1e+00	Prr5l Retreg2
Right kidney weight	40399.64	1	1	33.3	1e+00	Retreg2
Tail length	14461.17	2	1	33.3	1e+00	Retreg2 Ttc19
Length with tail	1484.46	1	1	33.3	1e+00	Retreg2
Length without tail	47233.74	1	1	33.3	1e+00	Retreg2
Liver weight, left	3487.23	1	1	33.3	1e+00	Retreg2
Liver weight, right	18.77	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Parametrial fat weight	62.38	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Retroperitoneal fat weight	3938.69	1	1	33.3	1e+00	Retreg2
Intraocular pressure	10386.52	1	1	33.3	1e+00	Retreg2
Extensor digitorum longus weight	1077.67	1	1	33.3	1e+00	Retreg2
Soleus weight	11.56	2	1	33.3	1e+00	Prr5l Retreg2
Tibialis anterior weight	585.45	2	2	66.7	1e+00	Prr5l Retreg2
Tibia length	392.79	2	2	66.7	1e+00	Prr5l Retreg2
Number of licking bursts	22477.35	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Food consumed during 24 hour testing period	17759.68	2	1	33.3	1e+00	Retreg2 Ttc19
Times rat made contact with spout	55.66	2	2	66.7	1e+00	Retreg2 Ttc19
Mean time between licks in bursts	55816.36	2	1	33.3	1e+00	Prr5l Retreg2
Mean num. licks in bursts	28390.25	2	2	66.7	1e+00	Retreg2 Ttc19
Std. dev. time between licks in bursts	14877.35	2	1	33.3	1e+00	Prr5l Retreg2
Water consumed over 24 hours	11396.17	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Patch foraging indifference point 0 sec	13060.87	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Patch foraging indifference point AUC	25071.12	2	1	33.3	1e+00	Prr5l Retreg2
Indifference point function ln k	55646.82	1	1	33.3	1e+00	Retreg2
Indifference point function log k	55646.82	1	1	33.3	1e+00	Retreg2
Patch foraging total patch changes 0 sec	13986.01	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Patch foraging total patch changes 12 sec	775.38	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Patch foraging total patch changes 18 sec	40454.12	1	1	33.3	1e+00	Retreg2
Patch foraging total patch changes 24 sec	37402.37	2	1	33.3	1e+00	Prr5l Retreg2
Patch foraging total patch changes 6 sec	3899.43	2	1	33.3	1e+00	Prr5l Retreg2
Patch foraging time to switch 0 sec	33261.5	2	2	66.7	1e+00	Prr5l Retreg2
Patch foraging water rate 0 sec	30220.47	2	2	66.7	1e+00	Prr5l Retreg2
Patch foraging water rate 12 sec	35324.91	2	1	33.3	1e+00	Retreg2 Ttc19
Patch foraging water rate 18 sec	16871.85	2	1	33.3	1e+00	Prr5l Retreg2
Patch foraging water rate 24 sec	522.87	2	1	33.3	1e+00	Retreg2 Ttc19
Patch foraging water rate 6 sec	427.01	2	1	33.3	1e+00	Retreg2 Ttc19
Locomotor activity	14.12	1	0	0	1e+00	Ttc19
Locomotor testing distance	27661.69	1	1	33.3	1e+00	Retreg2
Locomotor testing rearing	63397.34	1	1	33.3	1e+00	Retreg2
Light reinforcement 1	66311.75	1	1	33.3	1e+00	Retreg2
Light reinforcement 2	36738.3	1	1	33.3	1e+00	Retreg2
Reaction time number correct	63471.78	1	1	33.3	1e+00	Retreg2
Reaction time mean minus median	59976.41	2	1	33.3	1e+00	Retreg2 Ttc19
Reaction time mean minus median AUC	123988.85	1	1	33.3	1e+00	Retreg2
Reaction time num false alarms	15357.42	1	1	33.3	1e+00	Retreg2
Reaction time num false alarms AUC	17510.28	2	1	33.3	1e+00	Prr5l Retreg2
Reaction time trials correct on left	63471.78	1	1	33.3	1e+00	Retreg2
Reaction time trials on left	60883.54	1	1	33.3	1e+00	Retreg2
Reaction time mean	29724.21	1	1	33.3	1e+00	Retreg2
Reaction time mean AUC	19385.91	2	1	33.3	1e+00	Prr5l Retreg2
Median of all reaction times	3950.5	2	1	33.3	1e+00	Prr5l Retreg2
Reaction time omissions	8364.84	1	1	33.3	1e+00	Retreg2
Reaction time false alarm rate	210.6	1	1	33.3	1e+00	Retreg2
Reaction time premature initiation rate	4872.53	2	1	33.3	1e+00	Retreg2 Ttc19
Reaction time premature initiations	26874.49	2	1	33.3	1e+00	Retreg2 Ttc19
Std. dev. reaction times	60865.09	1	1	33.3	1e+00	Retreg2
Reaction time trials completed	60883.54	1	1	33.3	1e+00	Retreg2
Reaction time trials AUC	62130.65	1	1	33.3	1e+00	Retreg2
Social response proportion	4391.73	2	1	33.3	1e+00	Retreg2 Ttc19
Social responses	642.91	2	1	33.3	1e+00	Prr5l Retreg2
Social time	5831.87	2	1	33.3	1e+00	Prr5l Retreg2
Conditioned locomotion	1400.08	1	1	33.3	1e+00	Retreg2
Cocaine response after cond. corrected	9566.67	2	1	33.3	1e+00	Prr5l Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	33.3	1e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	33.3	1e+00	Retreg2
Saline control response	3160.68	1	1	33.3	1e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	33.3	1e+00	Retreg2
Condit. Reinf. active-inactive response ratio	28713.86	1	1	33.3	1e+00	Retreg2
Condit. Reinf. active responses	2302.04	1	1	33.3	1e+00	Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	33.3	1e+00	Retreg2
Condit. Reinf. lever presses	3863.86	1	1	33.3	1e+00	Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	33.3	1e+00	Retreg2
Pavlov. Cond. lever latency	1272.83	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. magazine entry latency	6645.22	2	1	33.3	1e+00	Retreg2 Ttc19
Pavlov. Cond. change in total contacts	39811.91	1	1	33.3	1e+00	Retreg2
Pavlov. Cond. index score	12744.53	1	1	33.3	1e+00	Retreg2
Pavlov. Cond. latency score	8078.67	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. lever contacts	2672.31	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	33.3	1e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	17497.96	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	33.3	1e+00	Retreg2
Pavlov. Cond. response bias	585.8	2	1	33.3	1e+00	Prr5l Retreg2
Conditioned reinforcement - actives	100795.1	1	1	33.3	1e+00	Retreg2
Conditioned reinforcement - inactives	64866.71	1	1	33.3	1e+00	Retreg2
Conditioned locomotion	5169.99	2	1	33.3	1e+00	Prr5l Retreg2
Intermittent access intake day 1-15 change	127876.18	1	1	33.3	1e+00	Retreg2
Intermittent access intake escalation	126068.82	1	1	33.3	1e+00	Retreg2
Intermittent access intake escalation 2	36175.43	1	1	33.3	1e+00	Retreg2
Intermitt. access day 1 inactive lever presses	180612.88	1	1	33.3	1e+00	Retreg2
Intermitt. access day 15 inactive lever presses	123608.2	1	1	33.3	1e+00	Retreg2
Intermitt. access escalation Index	93297.07	1	1	33.3	1e+00	Retreg2
Intermittent access day 1 total infusions	66115.79	1	1	33.3	1e+00	Retreg2
Intermittent access day 15 total infusions	48731.91	1	1	33.3	1e+00	Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	33.3	1e+00	Retreg2
Intermittent access total infusions	181.04	1	1	33.3	1e+00	Retreg2
Intermittent access day 1 locomotion	34964.22	1	1	33.3	1e+00	Retreg2
Intermittent access day 15 total locomotion	85548.8	1	1	33.3	1e+00	Retreg2
Intermittent access total locomotion	116.36	1	1	33.3	1e+00	Retreg2
Intermittent access standard deviation	56983.55	2	1	33.3	1e+00	Prr5l Retreg2
Cocaine induced anxiety	69097.7	1	1	33.3	1e+00	Retreg2
Post-drug Anxiety	2381.11	2	1	33.3	1e+00	Prr5l Retreg2
Baseline Anxiety	16755.97	2	1	33.3	1e+00	Retreg2 Ttc19
Lifetime Intake	1655.49	1	1	33.3	1e+00	Retreg2
Incentive Sensitization - Responses	71347.91	1	1	33.3	1e+00	Retreg2
Incentive Sensitization - Breakpoint	55273.76	1	1	33.3	1e+00	Retreg2
Progressive ratio test 1 active lever presses	31979.35	1	1	33.3	1e+00	Retreg2
Progressive ratio test 1 breakpoint	30292.17	1	1	33.3	1e+00	Retreg2
Progressive ratio test 1 inactive lever presses	62205.59	1	1	33.3	1e+00	Retreg2
Progressive ratio test 2 active lever presses	15263.76	1	1	33.3	1e+00	Retreg2
Progressive ratio test 2 breakpoint	8542.35	1	1	33.3	1e+00	Retreg2
Progressive ratio test 2 inactive lever presses	72504.33	1	1	33.3	1e+00	Retreg2
Total sessions with >9 infusions	985.02	2	1	33.3	1e+00	Prr5l Retreg2
Short access day 1 total inactive lever presses	19711.09	2	1	33.3	1e+00	Prr5l Retreg2
Short access day 10 total inactive lever presses	69422.58	2	1	33.3	1e+00	Prr5l Retreg2
Short access day 1 total infusions	38385.19	1	1	33.3	1e+00	Retreg2
Short access day 10 total infusions	11352.13	2	1	33.3	1e+00	Prr5l Retreg2
Short access total infusions	8778.92	1	1	33.3	1e+00	Retreg2
Short access day 1 locomotion	12408.44	2	1	33.3	1e+00	Prr5l Retreg2
Short access day 10 total locomotion	88176.71	1	1	33.3	1e+00	Retreg2
Short access total locomotion	9345.73	2	1	33.3	1e+00	Prr5l Retreg2
Compulsive drug intake	18679.82	1	1	33.3	1e+00	Retreg2
One hour access (0.3 mA shock)	2329.1	1	1	33.3	1e+00	Retreg2
One hour access (shock baseline)	54988.81	1	1	33.3	1e+00	Retreg2
Number of responses in last shaping day	6822.98	2	2	66.7	1e+00	Prr5l Retreg2
Context. condit. distance diff. score	112.13	2	1	33.3	1e+00	Retreg2 Ttc19
Locomotion velocity, session 1	3523.61	1	1	33.3	1e+00	Retreg2
Locomotion distance, session 1	519.97	2	1	33.3	1e+00	Retreg2 Ttc19
Locomotion velocity, session 2	2158.08	1	1	33.3	1e+00	Retreg2
Locomotion distance, session 2	267.35	2	2	66.7	1e+00	Retreg2 Ttc19
Locomotion velocity, session 3	264.95	2	1	33.3	1e+00	Prr5l Retreg2
Locomotion distance, session 3	4009.46	1	1	33.3	1e+00	Retreg2
Stereotopy head waving bouts, day 3	690.76	2	1	33.3	1e+00	Prr5l Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	33.3	1e+00	Retreg2
Locomotion velocity, session 7	292.79	1	1	33.3	1e+00	Retreg2
Locomotion distance, session 7	856.72	1	1	33.3	1e+00	Retreg2
Stereotopy head waving bouts, day 7	841.53	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Stereotopy head waving duration, day 7	709.29	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Locomotion velocity, session 8	207.96	2	1	33.3	1e+00	Prr5l Retreg2
Locomotion distance, session 8	147.88	1	1	33.3	1e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	33.3	1e+00	Retreg2
Degree of sensitization stereotypy	1024.63	2	1	33.3	1e+00	Retreg2 Ttc19
Condit. Reinf. active-inactive response ratio	97.69	3	2	66.7	1e+00	Prr5l Retreg2 Ttc19
Condit. Reinf. active responses	936.93	3	2	66.7	1e+00	Prr5l Retreg2 Ttc19
Condit. Reinf. inactive responses	2343.08	2	1	33.3	1e+00	Prr5l Retreg2
Incentive salience index mean	1199.76	3	2	66.7	1e+00	Prr5l Retreg2 Ttc19
Condit. Reinf. lever presses	2659.85	2	2	66.7	1e+00	Prr5l Retreg2
Time in familiar zone, hab. session 1	5591.75	2	1	33.3	1e+00	Prr5l Retreg2
Time in novel zone, hab. session 1	4630.69	2	2	66.7	1e+00	Prr5l Retreg2
Total zone transitions, hab. session 1	226.51	2	2	66.7	1e+00	Retreg2 Ttc19
Total locomotion distance, hab. session 1	206.57	2	1	33.3	1e+00	Retreg2 Ttc19
Locomotion velocity, hab. session 1	140.18	2	1	33.3	1e+00	Retreg2 Ttc19
Time in familiar zone, hab. session 2	2945.69	2	1	33.3	1e+00	Prr5l Retreg2
Time in novel zone, hab. session 2	3159.15	2	1	33.3	1e+00	Prr5l Retreg2
Total zone transitions, hab. session 2	36.64	2	1	33.3	1e+00	Prr5l Retreg2
Total locomotion distance, hab. session 2	14.11	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Locomotion velocity, hab. session 2	22.47	2	1	33.3	1e+00	Prr5l Retreg2
Novel to familiar place preference ratio	5123.54	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Novelty place preference	4985.59	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Time in novel zone, NPP test	3573.43	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Total zone transitions, NPP test	651.02	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Total locomotion distance, NPP test	847.99	2	1	33.3	1e+00	Retreg2 Ttc19
Locomotion velocity, NPP test	479.79	2	1	33.3	1e+00	Retreg2 Ttc19
Pavlov. Cond. lever latency	250.53	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. magazine entry latency	9.88	1	0	0	1e+00	Prr5l
Pavlov. Cond. change in total contacts	531.27	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. index score	198.49	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. latency score	208.89	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. lever contacts	344.44	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. magazine entry number	257.89	2	2	66.7	1e+00	Prr5l Retreg2
Pavlov. Cond. intertrial magazine entries	60.1	3	2	66.7	1e+00	Prr5l Retreg2 Ttc19
Pavlov. Cond. lever-magazine prob. diff.	214.47	2	1	33.3	1e+00	Prr5l Retreg2
Pavlov. Cond. response bias	301.93	2	1	33.3	1e+00	Prr5l Retreg2
Bone: apparent density	2734.25	2	1	33.3	1e+00	Prr5l Retreg2
Bone surface	3104.42	2	1	33.3	1e+00	Prr5l Retreg2
Bone volume	8624.75	1	1	33.3	1e+00	Retreg2
Bone: connectivity density	568.63	3	2	66.7	1e+00	Prr5l Retreg2 Ttc19
Bone: cortical apparent density	6014.2	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: cortical area	2295.68	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: cortical porosity	165.19	3	3	100	1e+00	Prr5l Retreg2 Ttc19
Bone: cortical porosity	391.01	3	3	100	1e+00	Prr5l Retreg2 Ttc19
Bone: cortical thickness	130.99	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Bone: cortical thickness	1465.84	2	1	33.3	1e+00	Prr5l Retreg2
Bone: cortical tissue density	6505.83	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: elastic displacement	3806.2	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: elastic work	127.05	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Bone: endosteal estimation	8913.19	1	1	33.3	1e+00	Retreg2
Bone: endosteal perimeter	5933.62	2	1	33.3	1e+00	Prr5l Retreg2
Bone: final force	803.35	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: final moment	112.59	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: marrow area	9430.07	1	1	33.3	1e+00	Retreg2
Bone: maximum diameter	3036.39	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: maximum force	4350.98	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: maximum moment	2996.94	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: minimum diameter	4100.86	1	1	33.3	1e+00	Retreg2
Bone: periosteal estimation	9791.57	1	1	33.3	1e+00	Retreg2
Bone: periosteal perimeter	11400.25	1	1	33.3	1e+00	Retreg2
Bone: post-yield work	4561	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Bone: stiffness	4518.45	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: tissue strength	1003.69	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Bone: trabecular number	3584.68	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Bone: trabecular spacing	3979.7	2	1	33.3	1e+00	Retreg2 Ttc19
Bone: trabecular thickness	4242.86	2	1	33.3	1e+00	Prr5l Retreg2
Bone: trabecular tissue density	7286.63	2	2	66.7	1e+00	Prr5l Retreg2
Breakpoint value in progressive ratio session	37605.61	1	1	33.3	1e+00	Retreg2
Distance traveled before self-admin	25270.93	2	1	33.3	1e+00	Retreg2 Ttc19
Distance traveled after self-admin	16236.13	2	1	33.3	1e+00	Retreg2 Ttc19
Delta time in closed arm before/after self-admin	244.69	1	1	33.3	1e+00	Retreg2
Delta time in open arm before/after self-admin	15131.21	1	1	33.3	1e+00	Retreg2
Diff in mean of infusions in LGA sessions	36650	1	1	33.3	1e+00	Retreg2
Extinction: sum of active levers before priming	28373.8	1	1	33.3	1e+00	Retreg2
Active lever presses in extinction session 6	738.98	1	1	33.3	1e+00	Retreg2
Delta distance traveled before/after self-admin	2940.47	1	1	33.3	1e+00	Retreg2
Delta ambulatory time before/after self-admin	30849.75	1	1	33.3	1e+00	Retreg2
Time in closed arm before self-admin	26866.11	1	1	33.3	1e+00	Retreg2
Time in closed arm after self-admin	4591.18	1	1	33.3	1e+00	Retreg2
Time in open arm before self-admin	8746.25	1	1	33.3	1e+00	Retreg2
Time in open arm after self-admin	477.73	1	1	33.3	1e+00	Retreg2
Sum of active levers in priming session hrs 5-6	978.69	1	1	33.3	1e+00	Retreg2
Time to tail flick, vehicle, before self-admin	13364.89	1	1	33.3	1e+00	Retreg2
Time to tail flick, vehicle, after self-admin	42142.71	1	1	33.3	1e+00	Retreg2
Time to tail flick, test, before self-admin	4073.45	2	1	33.3	1e+00	Prr5l Retreg2
Time to tail flick, test, after self-admin	473.84	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Delta time to tail flick, vehicle, before/after SA	9805.78	1	1	33.3	1e+00	Retreg2
Delta time to tail flick, test, before/after SA	15684.59	1	1	33.3	1e+00	Retreg2
Ambulatory time before self-admin	39441.93	2	1	33.3	1e+00	Retreg2 Ttc19
Ambulatory time after self-admin	13312.36	2	1	33.3	1e+00	Retreg2 Ttc19
Total heroin consumption	240.55	1	1	33.3	1e+00	Retreg2
Area under the delay curve	24791.27	1	1	33.3	1e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	33.3	1e+00	Retreg2
Delay disc. indifference point, 16s delay	21959.9	1	1	33.3	1e+00	Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	33.3	1e+00	Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	33.3	1e+00	Retreg2
Delay disc. indifference point, 4s delay	616.19	1	1	33.3	1e+00	Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	33.3	1e+00	Retreg2
Delay discount exponential model param	16922.54	1	1	33.3	1e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	33.3	1e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	33.3	1e+00	Retreg2
Change in fecal boli incidents, locomotor task	2843.08	2	1	33.3	1e+00	Prr5l Retreg2
Time >=10cm from walls, locomotor time 1	13009.3	1	1	33.3	1e+00	Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	33.3	1e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	33.3	1e+00	Retreg2
Rest time, locomotor task time 1	11179.4	2	1	33.3	1e+00	Prr5l Retreg2
Distance moved, locomotor task time 1	68821.85	1	1	33.3	1e+00	Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	33.3	1e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	33.3	1e+00	Retreg2
Bouts of movement, locomotor time 2	82029.05	1	1	33.3	1e+00	Retreg2
Total resting periods, locomotor time 2	99042.67	1	1	33.3	1e+00	Retreg2
Rest time, locomotor task time 2	25503.09	1	1	33.3	1e+00	Retreg2
Distance moved, locomotor task time 2	8477.87	1	1	33.3	1e+00	Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	33.3	1e+00	Retreg2
Weight adjusted by age	70782.25	1	1	33.3	1e+00	Retreg2
Seeking ratio, delayed vs. immediate footshock	13445.31	1	1	33.3	1e+00	Retreg2
Locomotion in novel chamber	1961.07	2	1	33.3	1e+00	Prr5l Retreg2
Locomotion in novel chamber post-restriction	65422.89	1	1	33.3	1e+00	Retreg2
Progressive ratio	22633.25	3	1	33.3	1e+00	Prr5l Retreg2 Ttc19
Food seeking constrained by brief footshock	1875.34	1	1	33.3	1e+00	Retreg2
Seeking ratio, punishment vs. effort	20644.22	2	1	33.3	1e+00	Prr5l Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	33.3	1e+00	Retreg2
Run reversals in cocaine runway, males	7664.74	1	1	33.3	1e+00	Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	33.3	1e+00	Retreg2
Latency to leave start box in cocaine runway, F	7166.92	1	1	33.3	1e+00	Retreg2
Latency to leave start box in cocaine runway, M	1716.51	1	1	33.3	1e+00	Retreg2
Cd content in liver	11.42	1	0	0	1e+00	Prr5l
Co content in liver	574.66	2	1	33.3	1e+00	Prr5l Retreg2
Cu content in liver	23.23	2	1	33.3	1e+00	Retreg2 Ttc19
Fe content in liver	1344.53	1	1	33.3	1e+00	Retreg2
K content in liver	763.17	2	1	33.3	1e+00	Retreg2 Ttc19
Mg content in liver	3020.33	2	1	33.3	1e+00	Prr5l Retreg2
Mn content in liver	1009.39	1	1	33.3	1e+00	Retreg2
Na content in liver	4018.36	1	1	33.3	1e+00	Retreg2
Rb content in liver	47.54	2	1	33.3	1e+00	Prr5l Retreg2
Se content in liver	13.53	1	0	0	1e+00	Prr5l
Zn content in liver	3745.55	1	1	33.3	1e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	Avg chisq
Adipose	alternative polyA	0	1.17
Adipose	alternative TSS	0	1.18
Adipose	gene expression	0	1.11
Adipose	isoform ratio	0	1.16
Adipose	intron excision ratio	0	1.09
Adipose	mRNA stability	0	1.12
BLA	alternative polyA	0	1.19
BLA	alternative TSS	0	1.1
BLA	gene expression	0	1.14
BLA	isoform ratio	0	1.14
BLA	intron excision ratio	0	1.07
BLA	mRNA stability	0	1.17
Brain	alternative polyA	0	1.15
Brain	alternative TSS	0	1.1
Brain	gene expression	0	1.14
Brain	isoform ratio	0	1.13
Brain	intron excision ratio	0	1.1
Brain	mRNA stability	0	1.15
Eye	alternative polyA	0	1.03
Eye	alternative TSS	0	1.14
Eye	gene expression	0	1.08
Eye	isoform ratio	0	1.15
Eye	intron excision ratio	0	1.11
Eye	mRNA stability	0	1.06
IC	alternative polyA	0	1.23
IC	alternative TSS	0	1.1
IC	gene expression	0	1.13
IC	isoform ratio	0	1.13
IC	intron excision ratio	0	1.09
IC	mRNA stability	0	1.11
IL	alternative polyA	0	1.12
IL	alternative TSS	0	0.96
IL	gene expression	0	1.14
IL	isoform ratio	0	1.21
IL	intron excision ratio	0	1.16
IL	mRNA stability	0	1.18
LHb	alternative polyA	0	1.17
LHb	alternative TSS	0	1.22
LHb	gene expression	0	1.13
LHb	isoform ratio	0	1.12
LHb	intron excision ratio	0	1.09
LHb	mRNA stability	0	1.2
Liver	alternative polyA	0	1.12
Liver	alternative TSS	0	1.06
Liver	gene expression	0	1.08
Liver	isoform ratio	1	1.08
Liver	intron excision ratio	0	1.13
Liver	mRNA stability	0	1.13
NAcc	alternative polyA	1	1.49
NAcc	alternative TSS	0	1.16
NAcc	gene expression	0	1.13
NAcc	isoform ratio	0	1.12
NAcc	intron excision ratio	0	1.13
NAcc	mRNA stability	0	1.14
OFC	alternative polyA	0	1.14
OFC	alternative TSS	0	1.12
OFC	gene expression	0	1.12
OFC	isoform ratio	0	1.21
OFC	intron excision ratio	0	1.07
OFC	mRNA stability	0	1.18
PL	alternative polyA	0	1.18
PL	alternative TSS	0	1.13
PL	gene expression	0	1.13
PL	isoform ratio	0	1.13
PL	intron excision ratio	0	1.08
PL	mRNA stability	0	1.14
pVTA	alternative polyA	0	1.22
pVTA	alternative TSS	0	1.18
pVTA	gene expression	0	1.14
pVTA	isoform ratio	0	1.11
pVTA	intron excision ratio	0	1.11
pVTA	mRNA stability	1	1.11
RMTg	alternative polyA	0	1.17
RMTg	alternative TSS	0	1.01
RMTg	gene expression	0	1.15
RMTg	isoform ratio	0	1.06
RMTg	intron excision ratio	0	0.99
RMTg	mRNA stability	0	1.2