Hub : Genes

Fam204a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Fam204a 0.19 0.11 7.3e-03 -0 0.01 -0.01 -0 3.5e-01 1.4e-01 7.0e-01 4.6e-01
2 LHb gene expression Fam204a 0.23 0.12 6.0e-04 0.11 0.13 0.11 0.12 1.2e-03 6.0e-04 1.5e-03 1.0e-03
3 Adipose mRNA stability Fam204a 0.04 0.02 5.3e-03 0 0.01 0.01 0.01 9.8e-02 3.9e-02 1.7e-02 2.0e-02
4 Brain gene expression Fam204a 0.16 0.08 1.5e-10 0.11 0.12 0.12 0.11 1.4e-10 2.3e-11 6.5e-11 1.8e-10
5 pVTA gene expression Fam204a 0.07 0.06 2.0e-03 0.04 0.03 0.03 0.03 1.5e-04 1.8e-03 9.8e-04 1.1e-03
6 IC gene expression Fam204a 0.15 0.09 6.1e-04 0.08 0.07 0.07 0.08 3.0e-04 5.4e-04 7.8e-04 3.4e-04
7 BLA gene expression Fam204a 0.32 0.17 2.3e-06 0.08 0.08 0.07 0.1 3.5e-05 3.4e-05 1.2e-04 9.3e-06
8 IL gene expression Fam204a 0.31 0.15 2.7e-03 0.03 0.09 0.1 0.09 7.1e-02 4.6e-03 2.2e-03 2.9e-03
9 PL gene expression Fam204a 0.1 0.05 4.0e-08 0.06 0.07 0.05 0.06 3.7e-07 2.2e-08 1.9e-06 2.3e-07
10 NAcc gene expression Fam204a 0.14 0.06 0.0e+00 0.12 0.13 0.13 0.12 8.3e-18 1.6e-18 8.8e-19 1.9e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.01.94.42.11.3-2.11.3-1.4-1.90.10.60.6-0.9
Area under the delay curve0.60.92.90.81.30.20.6-0.6-0.51.7-1.00.9-0.6
BMI with tail4.716.550.87.15.5-4.24.1-4.1-3.82.03.41.4-0.8
BMI without tail1.910.029.55.44.2-3.33.3-3.4-2.81.62.81.0-0.6
Body weight5.724.966.48.26.4-5.65.4-5.5-5.12.82.62.4-2.2
Weight adjusted by age0.20.51.71.00.6-0.70.5-0.3-0.40.01.3-0.30.6
Bone surface0.61.23.11.81.2-1.61.0-1.0-1.40.20.70.4-0.5
Bone volume1.01.95.12.31.6-1.71.3-1.3-1.70.41.00.4-0.7
Breakpoint value in progressive ratio session2.03.55.42.02.2-1.52.2-2.0-1.82.3-0.91.8-1.8
Number of licking bursts0.61.72.11.31.2-1.31.3-1.4-1.31.1-1.21.5-1.4
Context. condit. distance diff. score0.10.10.20.1-0.2-0.4-0.20.10.2-0.20.4-0.10.3
Locomotion velocity, session 10.40.51.0-1.0-0.90.6-0.70.90.7-0.7-0.2-0.40.4
Locomotion distance, session 11.92.53.8-1.8-1.51.8-1.81.71.9-1.30.7-1.31.5
Locomotion velocity, session 21.61.92.9-1.7-1.61.2-1.51.51.5-1.20.9-1.21.3
Locomotion distance, session 21.11.63.8-0.7-0.81.0-1.21.01.4-1.21.9-1.41.5
Locomotion velocity, session 30.40.51.3-1.1-0.90.6-0.90.70.8-0.4-0.0-0.30.4
Locomotion distance, session 30.80.91.4-1.2-1.10.8-1.00.91.1-1.00.5-0.70.8
Stereotopy head waving bouts, day 30.60.71.6-1.0-0.61.3-0.91.00.8-0.6-0.1-0.80.6
Stereotopy head waving duration, day 30.20.20.7-0.5-0.10.8-0.30.50.20.2-0.8-0.00.1
Locomotion velocity, session 70.00.10.40.20.0-0.6-0.1-0.0-0.1-0.10.10.20.1
Locomotion distance, session 70.40.52.0-0.0-0.5-0.4-0.50.50.3-1.11.4-0.70.8
Stereotopy head waving bouts, day 71.11.33.60.71.50.30.8-0.7-0.31.9-1.71.3-0.9
Stereotopy head waving duration, day 72.63.37.31.22.0-0.31.4-1.4-1.22.6-2.72.1-1.8
Locomotion velocity, session 80.20.30.8-0.7-0.9-0.2-0.50.30.5-0.90.0-0.10.2
Locomotion distance, session 81.21.73.2-1.0-1.50.3-1.31.11.4-1.81.6-1.21.4
Degree of sensitization distance0.40.41.40.90.4-1.20.6-0.5-0.7-0.10.80.1-0.0
Degree of sensitization stereotypy2.62.95.91.62.1-0.51.5-1.6-1.02.4-2.01.9-1.5
Conditioned locomotion0.20.20.60.20.40.00.4-0.3-0.20.7-0.70.5-0.6
Cocaine response after cond. corrected5.98.912.6-3.2-3.42.2-3.13.02.7-3.62.5-3.02.8
Cocaine response after cond. not corrected4.16.010.3-3.0-3.21.5-2.52.42.1-3.11.7-2.32.1
Cocaine response before conditioning2.12.53.80.90.9-1.81.7-1.7-1.61.2-2.01.8-1.8
Saline control response0.71.03.1-1.2-0.91.8-0.80.81.4-0.40.4-0.80.7
Bone: connectivity density0.30.41.70.80.3-1.30.3-0.5-1.1-0.30.20.2-0.3
Bone: cortical apparent density3.04.79.5-3.1-2.82.2-2.42.12.4-1.80.6-1.71.4
Bone: cortical area3.04.911.73.42.8-2.52.5-2.4-2.31.70.81.3-1.3
Bone: cortical porosity0.50.61.20.90.8-0.80.8-0.9-1.10.2-0.20.6-0.6
Bone: cortical porosity1.51.72.91.71.5-1.31.4-1.4-1.60.8-0.41.0-1.1
Bone: cortical thickness1.11.84.92.21.7-1.51.4-1.5-1.10.91.40.4-0.4
Bone: cortical thickness0.50.62.41.21.20.10.5-0.50.10.61.6-0.20.3
Bone: cortical tissue density3.04.79.8-3.1-2.92.2-2.52.12.4-1.80.5-1.71.3
Condit. Reinf. active minus inactive responses0.50.61.7-0.7-1.1-0.1-0.80.50.3-1.30.6-0.70.6
Condit. Reinf. active-inactive response ratio0.50.51.3-0.9-1.10.1-0.80.70.4-1.00.0-0.50.5
Condit. Reinf. active responses0.30.41.40.3-0.4-0.8-0.3-0.2-0.4-1.11.2-0.60.3
Condit. Reinf. inactive responses0.60.82.01.40.8-1.10.6-1.2-0.9-0.21.2-0.0-0.3
Incentive salience index mean0.91.22.7-0.9-1.40.0-1.20.70.6-1.71.4-1.21.1
Condit. Reinf. lever presses0.81.22.5-0.8-1.20.2-1.20.70.7-1.51.6-1.21.2
Condit. Reinf. active minus inactive responses1.42.23.41.81.7-1.51.8-1.5-1.71.0-0.91.4-1.4
Condit. Reinf. active-inactive response ratio1.21.92.91.71.7-1.31.7-1.2-1.51.1-0.81.3-1.2
Condit. Reinf. active responses2.53.56.12.52.2-1.92.0-2.0-2.11.3-1.01.7-1.7
Condit. Reinf. inactive responses0.71.12.41.61.2-1.01.1-1.2-1.10.8-0.30.9-0.9
Condit. Reinf. lever presses1.11.63.31.81.5-1.31.3-1.4-1.40.7-0.21.0-1.0
Condit. Reinf. lever reinforcers received1.82.64.32.11.7-1.71.7-1.7-1.91.0-0.91.4-1.6
Conditioned reinforcement - actives0.52.03.7-1.9-1.61.7-1.41.51.6-1.20.4-1.11.0
Conditioned reinforcement - inactives0.20.51.50.10.3-0.40.5-0.5-0.70.6-1.20.8-1.0
Conditioned locomotion2.02.94.9-2.2-1.92.1-1.71.92.0-1.30.4-1.51.2
Patch foraging indifference point 0 sec0.61.64.52.11.9-1.01.3-1.3-1.21.10.80.6-0.5
Patch foraging indifference point AUC0.40.91.20.81.0-0.60.9-1.0-0.91.0-1.11.0-1.1
Delay disc. indifference point, 0s delay0.20.20.6-0.00.10.6-0.20.40.5-0.00.8-0.40.6
Delay disc. indifference point, 16s delay0.60.92.90.81.30.20.7-0.5-0.51.7-1.31.0-0.6
Delay disc. indifference point, 2s delay0.40.41.5-0.5-0.11.2-0.70.70.80.40.3-0.40.7
Delay disc. indifference point, 24s delay0.61.02.20.91.5-0.10.9-0.8-0.81.5-1.01.1-0.8
Delay disc. indifference point, 4s delay0.50.51.30.71.10.20.5-0.5-0.41.1-0.80.8-0.5
Delay disc. indifference point, 8s delay0.30.51.70.51.00.20.4-0.4-0.41.3-1.00.7-0.6
Indifference point function ln k0.30.82.1-0.4-0.80.4-0.80.70.7-1.01.5-1.11.1
Indifference point function log k0.30.82.1-0.4-0.80.4-0.80.70.7-1.01.5-1.11.1
Patch foraging total patch changes 0 sec0.72.05.52.42.1-1.11.5-1.4-1.41.20.80.7-0.6
Patch foraging total patch changes 12 sec1.41.94.12.01.9-1.31.5-1.5-1.51.10.11.0-1.0
Patch foraging total patch changes 18 sec0.92.13.51.91.7-1.51.6-1.6-1.71.1-0.31.1-1.4
Patch foraging total patch changes 24 sec0.62.12.81.51.6-1.31.4-1.6-1.71.4-0.91.4-1.6
Patch foraging total patch changes 6 sec2.13.65.92.42.3-1.72.0-2.3-2.02.0-0.41.5-1.6
Patch foraging time to switch 0 sec0.10.31.0-1.0-0.80.2-0.40.60.2-0.6-0.3-0.2-0.0
Patch foraging water rate 0 sec0.10.51.91.41.1-0.40.5-0.7-0.50.60.60.10.1
Patch foraging water rate 12 sec0.31.23.21.81.6-0.91.3-1.1-1.00.90.00.8-0.6
Patch foraging water rate 18 sec0.40.92.2-0.2-0.40.8-0.71.00.8-0.61.5-1.11.3
Patch foraging water rate 24 sec0.50.82.80.50.30.7-0.60.60.6-0.41.7-1.21.2
Patch foraging water rate 6 sec0.20.31.20.40.20.3-0.00.10.2-0.51.1-0.70.6
Seeking ratio, delayed vs. immediate footshock1.62.35.0-2.2-2.20.8-2.01.51.3-1.60.1-1.10.9
Distance traveled before self-admin2.75.88.2-2.7-2.32.9-2.52.82.8-1.91.5-2.22.3
Distance traveled after self-admin1.52.65.0-2.2-1.81.9-1.81.81.8-1.10.5-1.31.3
Extensor digitorum longus weight0.31.23.01.71.2-1.51.3-1.1-1.20.50.60.4-0.5
Bone: elastic displacement0.10.21.0-0.4-0.01.0-0.10.30.60.20.1-0.30.2
Bone: elastic work0.71.02.5-0.3-0.01.5-0.60.81.1-0.01.6-1.11.1
Bone: endosteal estimation0.30.72.11.41.2-0.90.9-0.7-0.90.40.50.3-0.3
Bone: endosteal perimeter0.81.94.42.12.1-0.91.5-1.3-1.31.5-0.20.9-0.9
Epididymis fat weight7.738.985.29.27.5-7.56.7-6.7-7.04.20.54.3-3.9
Delta time in closed arm before/after self-admin1.61.52.2-1.0-1.30.7-1.21.31.1-1.51.4-1.31.3
Delta time in open arm before/after self-admin4.65.47.02.11.9-2.42.6-2.6-2.32.5-1.82.3-2.4
Diff in mean of infusions in LGA sessions0.81.43.41.01.4-0.61.2-1.1-1.01.8-1.01.2-1.0
Delay discount exponential model param0.60.82.9-0.8-1.4-0.3-0.60.50.5-1.71.0-0.90.6
Extinction: sum of active levers before priming0.91.31.81.31.4-1.11.3-1.1-1.11.1-0.71.2-1.1
Active lever presses in extinction session 60.50.51.50.91.2-0.20.9-0.5-0.51.00.10.6-0.4
Bone: final force1.01.64.72.21.7-1.31.2-1.0-1.30.51.40.1-0.2
Bone: final moment1.11.85.32.31.7-1.51.4-1.1-1.50.51.40.2-0.3
Food consumed during 24 hour testing period0.10.21.2-0.1-0.30.1-0.1-0.00.4-0.41.1-0.50.5
Glucose4.26.711.23.33.3-2.03.0-2.6-2.52.8-1.22.3-2.1
Heart weight3.15.012.53.52.8-2.42.6-2.6-2.11.41.01.3-1.0
Delay discount hyperbolic model param0.60.83.0-0.7-1.4-0.4-0.60.50.4-1.71.0-0.90.5
Intermittent access intake day 1-15 change0.10.40.9-0.9-0.60.9-0.40.90.6-0.20.0-0.40.4
Intermittent access intake escalation0.00.20.4-0.7-0.40.6-0.10.60.40.0-0.1-0.20.2
Intermittent access intake escalation 20.10.20.4-0.6-0.50.5-0.10.50.5-0.10.4-0.40.4
Intermitt. access day 1 inactive lever presses0.33.95.32.01.8-2.32.1-2.2-2.31.6-1.41.8-2.0
Intermitt. access day 15 inactive lever presses0.20.91.70.91.1-0.61.1-1.1-0.91.3-0.60.8-0.8
Intermitt. access escalation Index0.00.10.2-0.0-0.3-0.50.1-0.0-0.2-0.3-0.1-0.0-0.3
Intermittent access day 1 total infusions0.00.10.3-0.5-0.40.3-0.30.20.3-0.1-0.1-0.20.1
Intermittent access day 15 total infusions0.10.20.7-0.8-0.50.7-0.20.60.4-0.0-0.3-0.20.0
Intermittent access terminal intake (last 3 days)0.10.10.3-0.4-0.10.5-0.00.30.20.3-0.50.0-0.1
Intermittent access total infusions0.10.10.4-0.6-0.40.4-0.30.30.3-0.1-0.4-0.1-0.1
Intermittent access day 1 locomotion0.61.12.7-1.1-0.81.6-1.31.11.3-0.50.1-0.90.8
Intermittent access day 15 total locomotion0.20.71.90.40.9-0.10.6-0.5-0.61.1-1.40.9-0.9
Intermittent access total locomotion0.91.12.0-1.2-1.01.4-1.21.31.2-0.80.2-1.00.8
Intermittent access standard deviation0.10.71.50.40.90.10.9-0.2-0.61.2-1.20.9-0.9
Left kidney weight0.54.115.53.22.1-1.81.6-1.6-1.1-0.43.9-0.50.9
Right kidney weight0.74.922.53.31.9-1.91.4-1.3-1.0-0.94.7-1.11.2
Cocaine induced anxiety0.92.44.7-2.2-1.91.7-1.61.71.7-0.90.4-1.31.2
Post-drug Anxiety0.00.00.1-0.1-0.3-0.2-0.0-0.00.00.3-0.1-0.00.1
Baseline Anxiety2.44.06.42.52.2-2.22.1-2.3-2.11.7-1.01.8-1.7
Tail length0.42.03.21.31.2-1.41.8-1.7-1.41.3-0.81.3-1.6
Length with tail1.04.68.12.82.4-2.52.6-2.5-2.31.5-0.01.6-1.8
Length without tail1.57.715.33.93.3-3.13.1-2.9-3.12.0-0.32.1-2.2
Times rat made contact with spout0.10.20.70.60.3-0.30.3-0.3-0.1-0.30.9-0.10.2
Lifetime Intake0.20.20.6-0.8-0.60.6-0.50.50.5-0.3-0.2-0.30.1
Liver weight, left2.13.510.43.22.5-1.91.9-2.0-1.91.01.40.7-0.6
Liver weight, right0.71.25.71.60.7-1.00.3-0.5-0.5-1.02.4-0.70.8
Locomotor activity0.00.00.0-0.2-0.20.1-0.0-0.00.20.0-0.20.0-0.1
Locomotor testing distance0.51.32.1-1.5-1.41.1-1.11.11.2-1.10.8-1.00.9
Locomotor testing rearing0.10.50.9-0.9-0.61.0-0.50.80.8-0.30.0-0.50.6
Locomotion in novel chamber1.31.74.0-0.9-1.01.0-1.31.01.3-1.02.0-1.51.5
Locomotion in novel chamber post-restriction0.82.44.0-1.2-0.92.0-1.61.81.8-0.91.5-1.51.8
Fecal boli incidents, locomotor time 10.10.30.90.70.7-0.10.4-0.2-0.20.9-0.60.5-0.3
Change in fecal boli incidents, locomotor task0.20.20.80.2-0.2-0.50.1-0.2-0.2-0.80.9-0.30.2
Time >=10cm from walls, locomotor time 10.00.00.0-0.0-0.10.00.0-0.10.1-0.2-0.10.1-0.0
Bouts of movement, locomotor time 10.81.01.90.80.7-0.91.2-1.2-0.91.4-0.51.0-1.1
Total resting periods, locomotor time 10.30.40.80.40.3-0.60.9-0.8-0.60.9-0.10.5-0.7
Rest time, locomotor task time 10.81.32.7-1.0-1.20.5-0.81.10.9-1.11.6-1.41.2
Distance moved, locomotor task time 10.10.30.70.40.70.10.2-0.4-0.30.5-0.80.6-0.3
Vertical activity count, locomotor time 10.00.10.20.00.20.5-0.30.00.20.1-0.30.10.1
Time >=10cm from walls, locomotor time 20.10.10.60.20.0-0.0-0.30.00.1-0.70.8-0.40.4
Bouts of movement, locomotor time 20.00.10.3-0.5-0.40.3-0.00.30.2-0.2-0.1-0.1-0.1
Total resting periods, locomotor time 20.00.10.3-0.6-0.40.3-0.00.30.2-0.1-0.2-0.1-0.1
Rest time, locomotor task time 20.10.20.5-0.7-0.60.4-0.20.50.4-0.40.0-0.30.2
Distance moved, locomotor task time 20.00.10.20.00.00.1-0.30.00.1-0.10.5-0.20.3
Vertical activity count, locomotor time 20.00.00.30.1-0.0-0.0-0.4-0.10.1-0.00.5-0.20.2
Light reinforcement 10.41.83.0-1.2-1.31.1-1.31.11.3-1.51.7-1.41.4
Light reinforcement 20.30.60.9-0.8-0.90.7-0.70.70.9-0.80.7-0.60.7
Bone: marrow area0.30.82.31.51.2-0.90.9-0.8-0.90.40.60.3-0.3
Bone: maximum diameter3.46.913.03.63.2-2.62.9-2.9-2.62.4-0.62.1-2.2
Bone: maximum force0.61.13.31.81.2-1.20.8-0.6-1.1-0.01.7-0.20.1
Bone: maximum moment0.71.33.71.91.3-1.41.0-0.8-1.20.11.6-0.1-0.1
Mean time between licks in bursts0.21.33.00.80.4-1.71.1-1.4-1.30.5-0.91.1-1.3
Mean num. licks in bursts0.92.54.4-1.1-1.31.3-1.41.51.4-1.62.1-1.81.9
Cd content in liver2.73.03.6-1.7-1.71.6-1.61.81.9-1.81.5-1.71.8
Co content in liver1.61.93.8-1.0-1.11.1-1.41.41.2-1.21.9-1.61.6
Cu content in liver0.00.00.1-0.00.10.30.10.00.1-0.2-0.1-0.1-0.2
Fe content in liver2.63.35.62.11.6-2.41.8-2.0-2.11.0-1.01.7-1.8
K content in liver0.20.20.70.10.3-0.10.5-0.2-0.60.4-0.80.3-0.7
Mg content in liver0.20.21.0-0.6-0.21.0-0.20.60.5-0.0-0.2-0.40.2
Mn content in liver0.10.10.3-0.2-0.20.3-0.20.40.2-0.30.5-0.40.4
Na content in liver0.60.71.40.91.2-0.31.0-0.5-0.81.0-0.70.7-0.7
Rb content in liver0.10.20.40.30.50.10.4-0.3-0.30.5-0.60.3-0.6
Se content in liver0.00.00.1-0.3-0.2-0.20.00.1-0.10.0-0.40.1-0.2
Sr content in liver4.74.17.0-2.7-2.22.2-2.22.42.0-1.50.6-1.72.0
Zn content in liver2.12.53.8-1.9-1.61.9-1.51.81.8-1.30.8-1.61.3
Bone: minimum diameter1.73.37.82.82.4-1.82.1-1.9-1.81.40.31.2-1.2
Time in familiar zone, hab. session 10.20.20.70.70.90.30.4-0.30.10.70.20.10.3
Time in novel zone, hab. session 10.40.41.7-0.3-0.4-0.60.2-0.3-0.5-0.3-1.30.7-0.9
Total zone transitions, hab. session 10.20.20.5-0.3-0.10.7-0.60.40.7-0.20.5-0.50.6
Total locomotion distance, hab. session 10.20.30.60.50.4-0.80.5-0.7-0.40.2-0.50.7-0.6
Locomotion velocity, hab. session 10.10.10.60.30.2-0.80.3-0.5-0.3-0.1-0.10.4-0.3
Time in familiar zone, hab. session 22.02.24.71.31.0-2.21.5-1.4-1.80.9-1.41.7-1.5
Time in novel zone, hab. session 21.31.43.0-0.9-0.61.7-1.01.11.7-0.91.1-1.21.2
Total zone transitions, hab. session 20.20.20.5-0.1-0.00.5-0.40.30.7-0.40.7-0.40.6
Total locomotion distance, hab. session 20.10.20.40.60.5-0.50.4-0.5-0.1-0.20.40.3-0.0
Locomotion velocity, hab. session 20.10.20.40.70.6-0.50.5-0.5-0.1-0.10.40.3-0.0
Novel to familiar place preference ratio0.10.10.30.50.3-0.20.4-0.6-0.10.0-0.10.3-0.5
Novelty place preference0.00.10.20.30.1-0.10.3-0.40.0-0.1-0.10.2-0.4
Time in novel zone, NPP test0.30.40.80.90.6-0.50.7-0.8-0.40.1-0.50.7-0.8
Total zone transitions, NPP test0.50.72.6-0.2-0.50.1-0.70.40.7-1.01.6-0.91.0
Total locomotion distance, NPP test0.30.41.5-0.1-0.4-0.1-0.40.20.5-1.01.2-0.60.6
Locomotion velocity, NPP test0.81.23.5-0.7-1.00.3-1.00.71.0-1.21.9-1.21.1
Intraocular pressure1.52.53.41.71.6-1.61.4-1.6-1.91.1-1.41.6-1.8
Delta distance traveled before/after self-admin0.10.10.4-0.10.1-0.20.2-0.3-0.40.4-0.60.4-0.4
Delta ambulatory time before/after self-admin0.20.40.60.30.4-0.60.4-0.7-0.70.5-0.80.6-0.7
Parametrial fat weight10.123.853.57.35.9-5.75.5-5.6-5.23.21.43.1-2.9
Pavlov. Cond. lever latency0.40.52.00.10.2-0.40.5-0.4-0.60.7-1.40.8-1.0
Pavlov. Cond. magazine entry latency0.20.30.60.80.5-0.70.4-0.6-0.4-0.20.70.1-0.1
Pavlov. Cond. change in total contacts0.50.61.81.31.0-0.70.9-1.0-0.50.20.70.4-0.2
Pavlov. Cond. index score0.20.20.90.70.4-0.40.3-0.5-0.2-0.10.9-0.10.2
Pavlov. Cond. latency score0.10.21.00.50.3-0.30.1-0.3-0.1-0.21.0-0.20.4
Pavlov. Cond. lever contacts0.10.20.70.60.50.10.1-0.20.10.00.8-0.20.4
Pavlov. Cond. magazine entry number0.20.30.7-0.8-0.50.6-0.50.60.40.1-0.6-0.10.0
Pavlov. Cond. intertrial magazine entries0.40.53.10.5-0.1-0.3-0.2-0.10.1-0.71.8-0.80.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.80.90.5-0.60.4-0.6-0.3-0.10.90.00.1
Pavlov. Cond. response bias0.10.20.90.50.3-0.10.0-0.10.0-0.30.9-0.30.4
Pavlov. Cond. lever latency1.72.43.7-1.9-1.61.8-1.71.71.9-0.80.7-1.41.7
Pavlov. Cond. magazine entry latency0.91.31.81.21.2-1.21.0-1.1-1.21.1-1.11.4-1.1
Pavlov. Cond. change in total contacts0.71.62.11.41.3-1.31.4-1.3-1.30.8-1.01.3-1.5
Pavlov. Cond. index score1.21.92.71.61.4-1.61.4-1.5-1.60.9-0.91.3-1.4
Pavlov. Cond. latency score1.01.72.31.51.3-1.51.3-1.4-1.50.8-0.81.2-1.3
Pavlov. Cond. lever contacts1.01.52.51.61.3-1.31.3-1.3-1.50.6-0.51.0-1.3
Pavlov. Cond. magazine entry number0.50.71.0-1.0-1.00.8-0.70.70.9-0.70.8-0.90.8
Pavlov. Cond. intertrial magazine entries0.10.31.80.40.1-0.30.2-0.1-0.3-0.41.3-0.60.4
Pavlov. Cond. lever-magazine prob. diff.0.91.52.11.41.3-1.31.1-1.3-1.40.7-0.91.2-1.3
Pavlov. Cond. response bias1.82.53.71.91.6-1.71.6-1.7-1.81.0-0.91.5-1.7
Time in closed arm before self-admin0.00.00.1-0.2-0.20.1-0.20.10.10.0-0.1-0.10.2
Time in closed arm after self-admin2.12.43.3-1.6-1.71.3-1.61.81.5-1.61.2-1.51.6
Time in open arm before self-admin0.20.30.7-0.8-0.50.8-0.40.50.7-0.1-0.3-0.2-0.1
Time in open arm after self-admin3.03.35.51.41.5-1.41.9-2.0-1.52.3-1.91.9-2.0
Bone: periosteal estimation1.33.08.42.92.3-1.91.9-1.7-1.71.11.20.7-0.7
Bone: periosteal perimeter2.75.212.03.53.2-2.02.6-2.3-2.32.20.11.5-1.5
Bone: post-yield work0.40.62.61.10.4-1.60.5-0.5-1.1-0.30.60.3-0.3
Progressive ratio test 1 active lever presses0.30.51.0-1.0-0.71.0-0.80.80.8-0.1-0.1-0.50.4
Progressive ratio test 1 breakpoint0.30.51.0-1.0-0.71.0-0.70.90.80.0-0.1-0.50.4
Progressive ratio test 1 inactive lever presses0.20.40.90.40.5-0.50.4-0.6-0.60.9-1.00.7-0.8
Progressive ratio test 2 active lever presses0.00.10.2-0.30.00.5-0.10.40.1-0.0-0.2-0.1-0.0
Progressive ratio test 2 breakpoint0.00.00.2-0.20.10.4-0.00.40.0-0.0-0.2-0.0-0.1
Progressive ratio test 2 inactive lever presses0.10.20.50.20.1-0.70.4-0.4-0.70.0-0.40.3-0.6
Incentive Sensitization - Responses0.10.20.40.50.7-0.20.6-0.2-0.50.1-0.20.3-0.4
Incentive Sensitization - Breakpoint0.10.20.40.50.7-0.30.7-0.2-0.70.1-0.30.4-0.6
Sum of active levers in priming session hrs 5-60.90.81.40.80.8-1.11.2-1.0-1.10.5-0.40.8-1.1
Progressive ratio0.20.61.7-1.3-0.71.0-0.60.70.6-0.3-1.2-0.1-0.1
Food seeking constrained by brief footshock0.50.63.6-0.9-0.40.6-0.40.20.10.4-1.90.5-0.5
Seeking ratio, punishment vs. effort0.00.10.1-0.1-0.20.0-0.30.20.1-0.00.3-0.30.4
Retroperitoneal fat weight10.044.9108.710.48.2-8.17.1-7.4-7.24.02.24.1-3.6
Reaction time number correct0.10.51.00.91.00.10.7-0.7-0.30.9-0.50.6-0.7
Reaction time mean minus median0.00.20.5-0.30.10.7-0.40.70.2-0.2-0.4-0.20.3
Reaction time mean minus median AUC0.10.82.8-0.8-0.21.7-0.91.41.0-0.20.1-0.70.9
Reaction time num false alarms0.81.44.0-0.4-0.80.5-1.01.00.8-1.52.0-1.41.4
Reaction time num false alarms AUC0.51.23.8-0.3-0.60.7-0.91.00.9-1.21.9-1.31.4
Reaction time trials correct on left0.10.51.00.91.00.10.7-0.7-0.30.9-0.50.6-0.7
Reaction time trials on left0.20.51.00.91.00.00.8-0.7-0.41.0-0.50.6-0.7
Reaction time mean0.30.61.8-0.9-0.21.2-0.81.00.4-0.1-1.30.00.2
Reaction time mean AUC0.30.81.8-1.1-0.41.3-0.91.20.5-0.3-1.3-0.20.3
Median of all reaction times0.40.71.8-1.1-0.41.3-0.91.00.5-0.0-1.4-0.00.2
Reaction time omissions0.61.01.90.70.8-1.00.9-0.8-1.11.1-1.41.2-1.1
Reaction time false alarm rate0.91.23.5-0.4-0.80.3-1.01.00.7-1.41.9-1.21.4
Reaction time premature initiation rate0.10.10.5-0.3-0.30.1-0.70.40.2-0.00.3-0.40.4
Reaction time premature initiations0.00.00.20.20.20.1-0.20.0-0.00.40.1-0.10.1
Std. dev. reaction times0.00.10.5-0.00.30.4-0.20.6-0.2-0.0-0.70.10.1
Reaction time trials completed0.20.51.00.91.00.00.8-0.7-0.41.0-0.50.6-0.7
Reaction time trials AUC0.10.51.01.01.00.00.8-0.7-0.40.9-0.30.5-0.6
Run reversals in cocaine runway, females0.60.61.60.40.6-0.30.5-0.6-0.51.3-1.30.9-0.9
Run reversals in cocaine runway, males1.31.42.1-1.4-1.31.2-1.21.41.2-1.20.8-1.11.1
Latency to leave start box in cocaine runway1.01.33.30.30.9-0.01.2-1.0-0.61.6-1.81.3-1.2
Latency to leave start box in cocaine runway, F0.70.91.50.50.8-0.51.2-0.9-0.81.0-1.21.1-1.0
Latency to leave start box in cocaine runway, M0.50.51.90.10.60.70.4-0.50.21.4-0.90.6-0.4
Std. dev. time between licks in bursts0.10.20.5-0.3-0.6-0.7-0.2-0.0-0.3-0.6-0.40.1-0.2
Total sessions with >9 infusions0.50.61.2-1.0-0.71.0-1.10.80.8-0.7-0.1-0.60.5
Short access day 1 total inactive lever presses0.20.51.00.2-0.0-1.00.3-0.9-0.8-0.2-0.90.6-0.9
Short access day 10 total inactive lever presses0.10.40.90.80.4-0.90.4-0.3-0.7-0.80.9-0.20.1
Short access day 1 total infusions0.10.30.5-0.7-0.70.3-0.70.40.4-0.70.0-0.40.3
Short access day 10 total infusions0.91.42.8-1.7-1.41.5-1.31.11.5-0.60.3-1.00.9
Short access total infusions0.71.01.8-1.3-1.21.1-1.20.91.1-0.80.3-0.80.7
Short access day 1 locomotion0.00.10.3-0.2-0.00.5-0.4-0.10.2-0.2-0.3-0.10.0
Short access day 10 total locomotion0.20.71.7-0.9-0.71.3-1.01.01.1-0.10.1-0.70.7
Short access total locomotion1.52.34.5-1.7-1.32.1-1.91.61.8-1.00.4-1.41.3
One hour access (0.3 mA shock)0.91.02.00.40.7-0.91.0-0.9-1.10.8-1.41.2-1.4
Compulsive drug intake0.81.22.61.31.0-1.61.1-1.3-1.40.4-0.31.0-1.0
One hour access (shock baseline)0.10.31.1-1.0-0.70.6-0.40.50.5-0.3-0.5-0.20.0
Social response proportion0.50.62.20.0-0.50.4-0.80.20.6-0.91.5-1.00.9
Social responses1.11.43.51.91.5-1.21.1-1.5-1.10.9-0.00.9-0.7
Social time0.10.10.40.50.60.20.4-0.50.10.4-0.30.4-0.2
Soleus weight0.20.73.31.00.90.40.2-0.10.10.21.8-0.70.7
Bone: stiffness0.20.41.21.00.5-0.80.4-0.1-0.8-0.51.1-0.30.2
Tibialis anterior weight0.10.30.50.70.6-0.50.7-0.5-0.70.2-0.30.3-0.7
Time to tail flick, vehicle, before self-admin0.10.10.20.40.3-0.40.3-0.4-0.4-0.0-0.10.3-0.3
Time to tail flick, vehicle, after self-admin0.10.10.40.20.3-0.20.3-0.2-0.30.6-0.40.3-0.2
Time to tail flick, test, before self-admin2.73.15.3-1.9-1.52.3-1.91.72.0-1.50.9-1.61.8
Time to tail flick, test, after self-admin0.60.61.50.60.2-1.20.7-0.8-0.90.4-0.80.7-0.9
Delta time to tail flick, vehicle, before/after SA1.01.12.81.01.3-0.61.1-0.9-0.81.7-1.01.0-0.8
Delta time to tail flick, test, before/after SA1.21.54.21.40.6-2.01.3-1.2-1.40.8-0.40.9-1.2
Tibia length0.00.10.50.70.5-0.20.2-0.2-0.10.30.5-0.00.0
Ambulatory time before self-admin1.44.15.4-2.3-2.02.3-2.12.32.3-1.71.4-1.91.9
Ambulatory time after self-admin1.01.63.6-1.9-1.41.5-1.41.21.4-0.90.2-0.90.9
Bone: tissue strength0.40.40.90.30.5-0.40.7-0.6-0.60.7-1.00.8-0.8
Total heroin consumption2.83.36.52.42.6-1.32.0-1.6-1.72.4-0.51.6-1.3
Bone: trabecular number0.91.73.71.81.3-1.91.3-1.3-1.90.20.10.8-0.9
Bone: trabecular spacing0.30.41.3-1.1-1.00.3-0.50.40.7-0.3-0.80.1-0.2
Bone: trabecular thickness3.44.710.23.22.8-2.22.4-2.2-2.51.60.21.4-1.5
Bone: trabecular tissue density0.50.92.1-1.4-1.50.7-1.00.90.9-0.90.3-0.80.5
Water consumed over 24 hours0.30.61.3-0.4-0.50.9-0.40.50.9-0.81.1-0.80.9
Number of responses in last shaping day0.30.30.6-0.7-0.50.7-0.80.60.5-0.7-0.0-0.40.4