Hub : Genes

Fam204a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Fam204a 0.23 0.12 6.0e-04 0.11 0.13 0.11 0.12 1.2e-03 6.0e-04 1.5e-03 1.0e-03
2 Adipose mRNA stability Fam204a 0.04 0.02 5.3e-03 0 0.01 0.01 0.01 9.8e-02 3.9e-02 1.7e-02 2.0e-02
3 Brain gene expression Fam204a 0.16 0.08 1.5e-10 0.11 0.12 0.12 0.11 1.4e-10 2.3e-11 6.5e-11 1.7e-10
4 pVTA gene expression Fam204a 0.07 0.06 2.0e-03 0.04 0.03 0.03 0.03 1.5e-04 1.8e-03 1.0e-03 1.2e-03
5 IC gene expression Fam204a 0.15 0.09 6.1e-04 0.08 0.07 0.07 0.08 3.0e-04 5.4e-04 7.8e-04 3.2e-04
6 BLA gene expression Fam204a 0.32 0.17 2.3e-06 0.08 0.08 0.07 0.1 3.5e-05 3.4e-05 1.1e-04 9.7e-06
7 IL gene expression Fam204a 0.31 0.15 2.7e-03 0.03 0.09 0.1 0.09 7.1e-02 4.6e-03 2.2e-03 3.3e-03
8 PL gene expression Fam204a 0.1 0.05 4.0e-08 0.06 0.07 0.05 0.06 3.7e-07 2.2e-08 1.9e-06 2.4e-07
9 NAcc gene expression Fam204a 0.14 0.06 0.0e+00 0.12 0.13 0.13 0.12 8.3e-18 1.6e-18 8.8e-19 1.9e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.01.74.41.32.11.31.41.90.2-0.60.60.9
Area under the delay curve0.80.92.91.3-0.20.60.60.51.71.00.90.6
BMI with tail3.712.730.35.54.24.14.13.82.1-3.41.40.8
BMI without tail2.67.817.34.23.33.33.42.81.6-2.81.00.6
Body weight4.620.340.86.45.65.45.55.12.8-2.62.42.2
Weight adjusted by age0.30.41.70.60.70.50.30.40.0-1.3-0.3-0.6
Bone surface0.61.02.61.21.61.01.01.40.2-0.70.40.5
Bone volume0.91.53.01.61.71.31.31.70.4-1.00.40.7
Breakpoint value in progressive ratio session2.93.55.42.21.52.22.01.82.30.91.81.8
Number of licking bursts1.01.72.11.21.31.31.41.31.11.21.51.4
Context. condit. distance diff. score0.10.10.2-0.20.4-0.2-0.1-0.2-0.2-0.4-0.1-0.3
Locomotion velocity, session 10.40.40.9-0.9-0.6-0.7-0.9-0.7-0.70.2-0.4-0.4
Locomotion distance, session 11.92.43.8-1.5-1.8-1.8-1.7-1.9-1.3-0.7-1.3-1.5
Locomotion velocity, session 21.51.82.7-1.6-1.2-1.5-1.5-1.5-1.2-0.9-1.2-1.3
Locomotion distance, session 21.21.73.8-0.8-1.0-1.2-1.0-1.4-1.2-1.9-1.4-1.5
Locomotion velocity, session 30.30.40.8-0.9-0.6-0.9-0.7-0.8-0.40.0-0.3-0.4
Locomotion distance, session 30.80.81.2-1.1-0.8-1.0-0.9-1.1-1.0-0.5-0.7-0.8
Stereotopy head waving bouts, day 30.50.61.6-0.6-1.3-0.9-1.0-0.8-0.60.1-0.8-0.6
Stereotopy head waving duration, day 30.20.20.7-0.1-0.8-0.3-0.5-0.20.20.8-0.0-0.1
Locomotion velocity, session 70.00.10.40.00.6-0.10.00.1-0.1-0.10.2-0.1
Locomotion distance, session 70.50.62.0-0.50.4-0.5-0.5-0.3-1.1-1.4-0.7-0.8
Stereotopy head waving bouts, day 71.21.43.61.5-0.30.80.70.31.91.71.30.9
Stereotopy head waving duration, day 72.93.57.32.00.31.41.41.22.62.72.11.8
Locomotion velocity, session 80.20.20.8-0.90.2-0.5-0.3-0.5-0.8-0.0-0.1-0.2
Locomotion distance, session 81.31.83.2-1.5-0.3-1.3-1.1-1.4-1.8-1.6-1.2-1.4
Degree of sensitization distance0.40.41.40.41.20.60.50.7-0.1-0.80.10.0
Degree of sensitization stereotypy2.73.05.92.10.51.51.61.02.42.01.91.5
Conditioned locomotion0.20.20.60.4-0.00.40.30.20.70.70.50.6
Cocaine response after cond. corrected7.28.712.6-3.4-2.2-3.1-3.0-2.7-3.6-2.5-3.0-2.8
Cocaine response after cond. not corrected4.85.710.3-3.2-1.5-2.5-2.4-2.1-3.1-1.7-2.3-2.1
Cocaine response before conditioning2.22.73.80.91.81.71.71.61.22.01.81.8
Saline control response0.71.03.1-0.9-1.8-0.8-0.8-1.4-0.4-0.4-0.8-0.7
Bone: connectivity density0.20.41.70.31.30.30.51.1-0.3-0.20.20.3
Bone: cortical apparent density3.04.17.9-2.8-2.2-2.4-2.1-2.4-1.8-0.6-1.7-1.4
Bone: cortical area2.74.27.82.82.52.52.42.31.7-0.81.31.3
Bone: cortical porosity0.50.51.20.80.80.80.91.10.20.20.60.6
Bone: cortical porosity1.41.52.61.51.31.41.41.60.80.41.01.1
Bone: cortical thickness0.91.52.81.71.51.41.51.10.9-1.40.40.4
Bone: cortical thickness0.50.52.41.2-0.10.50.5-0.10.6-1.6-0.2-0.3
Bone: cortical tissue density3.04.18.1-2.9-2.2-2.5-2.1-2.4-1.8-0.5-1.7-1.3
Condit. Reinf. active minus inactive responses0.50.61.7-1.10.1-0.8-0.5-0.3-1.3-0.6-0.7-0.6
Condit. Reinf. active-inactive response ratio0.40.51.3-1.1-0.1-0.8-0.7-0.4-1.0-0.0-0.5-0.5
Condit. Reinf. active responses0.40.51.4-0.40.8-0.30.20.4-1.1-1.2-0.6-0.3
Condit. Reinf. inactive responses0.50.71.50.81.10.61.20.9-0.1-1.2-0.00.3
Incentive salience index mean1.01.32.7-1.4-0.0-1.2-0.7-0.6-1.7-1.4-1.2-1.1
Condit. Reinf. lever presses0.91.32.5-1.2-0.2-1.2-0.7-0.7-1.5-1.6-1.2-1.2
Condit. Reinf. active minus inactive responses1.62.13.11.71.51.81.51.71.00.91.41.4
Condit. Reinf. active-inactive response ratio1.61.82.91.71.31.71.21.51.10.81.31.2
Condit. Reinf. active responses2.33.34.72.21.92.02.02.11.31.01.71.7
Condit. Reinf. inactive responses0.70.91.51.21.01.11.21.10.80.30.90.9
Condit. Reinf. lever presses1.01.42.31.51.31.31.41.40.70.21.01.0
Condit. Reinf. lever reinforcers received1.72.43.51.71.71.71.71.91.00.91.41.6
Conditioned reinforcement - actives1.01.82.8-1.6-1.7-1.4-1.5-1.6-1.2-0.4-1.1-1.0
Conditioned reinforcement - inactives0.40.51.50.30.40.50.50.70.61.20.81.0
Conditioned locomotion2.12.74.5-1.9-2.1-1.7-1.9-2.0-1.3-0.4-1.5-1.2
Patch foraging indifference point 0 sec0.71.33.51.91.01.31.31.21.1-0.80.60.5
Patch foraging indifference point AUC0.71.01.21.00.60.91.00.91.01.11.01.1
Delay disc. indifference point, 0s delay0.20.20.60.1-0.6-0.2-0.4-0.5-0.0-0.8-0.4-0.6
Delay disc. indifference point, 16s delay0.80.92.91.3-0.20.70.50.51.71.31.00.6
Delay disc. indifference point, 2s delay0.40.51.5-0.1-1.2-0.7-0.7-0.80.4-0.3-0.4-0.7
Delay disc. indifference point, 24s delay0.91.02.21.50.10.90.80.81.51.01.10.8
Delay disc. indifference point, 4s delay0.50.51.31.1-0.20.50.50.41.10.80.80.5
Delay disc. indifference point, 8s delay0.50.61.71.0-0.20.40.40.41.31.00.70.6
Indifference point function ln k0.50.92.1-0.8-0.4-0.8-0.7-0.7-1.0-1.5-1.1-1.1
Indifference point function log k0.50.92.1-0.8-0.4-0.8-0.7-0.7-1.0-1.5-1.1-1.1
Patch foraging total patch changes 0 sec0.91.64.42.11.11.51.41.41.2-0.80.70.6
Patch foraging total patch changes 12 sec1.31.73.51.91.31.51.51.51.1-0.11.01.0
Patch foraging total patch changes 18 sec1.31.93.01.71.51.61.61.71.10.31.11.4
Patch foraging total patch changes 24 sec1.22.12.81.61.31.41.61.71.40.91.41.6
Patch foraging total patch changes 6 sec2.23.45.32.31.72.02.32.02.00.41.51.6
Patch foraging time to switch 0 sec0.10.20.7-0.8-0.2-0.4-0.6-0.2-0.60.3-0.20.1
Patch foraging water rate 0 sec0.20.31.31.10.40.50.70.50.6-0.60.1-0.1
Patch foraging water rate 12 sec0.51.02.61.60.91.31.11.00.9-0.00.80.6
Patch foraging water rate 18 sec0.61.02.2-0.4-0.8-0.7-1.0-0.8-0.6-1.5-1.1-1.4
Patch foraging water rate 24 sec0.60.82.80.3-0.7-0.6-0.6-0.6-0.4-1.7-1.2-1.3
Patch foraging water rate 6 sec0.20.31.20.2-0.3-0.0-0.1-0.2-0.5-1.1-0.7-0.6
Seeking ratio, delayed vs. immediate footshock1.72.05.0-2.2-0.8-2.0-1.5-1.3-1.6-0.1-1.1-0.9
Distance traveled before self-admin4.35.78.2-2.3-2.9-2.5-2.8-2.8-1.9-1.5-2.2-2.3
Distance traveled after self-admin1.92.43.4-1.8-1.9-1.8-1.8-1.8-1.1-0.5-1.3-1.3
Extensor digitorum longus weight0.31.02.11.21.51.31.11.20.5-0.60.40.5
Bone: elastic displacement0.20.21.0-0.0-1.0-0.1-0.3-0.60.2-0.1-0.3-0.2
Bone: elastic work0.81.12.5-0.0-1.5-0.6-0.8-1.1-0.0-1.6-1.1-1.1
Bone: endosteal estimation0.20.51.31.20.90.90.70.90.4-0.50.30.3
Bone: endosteal perimeter0.81.64.22.10.91.51.31.31.50.20.90.9
Epididymis fat weight9.933.756.87.57.56.76.77.04.2-0.54.33.9
Delta time in closed arm before/after self-admin1.71.52.2-1.3-0.7-1.2-1.3-1.1-1.5-1.4-1.3-1.3
Delta time in open arm before/after self-admin5.65.57.01.92.42.62.62.32.51.82.32.4
Diff in mean of infusions in LGA sessions1.21.43.41.40.61.21.11.01.81.01.21.0
Delay discount exponential model param0.80.92.9-1.40.3-0.6-0.5-0.5-1.7-1.0-0.9-0.6
Extinction: sum of active levers before priming1.21.31.81.41.11.31.11.11.10.71.21.1
Active lever presses in extinction session 60.50.51.51.20.20.90.50.51.0-0.10.60.4
Bone: final force0.81.22.81.71.31.21.01.30.5-1.40.10.2
Bone: final moment0.91.53.01.71.51.41.11.50.5-1.40.20.3
Food consumed during 24 hour testing period0.20.21.2-0.3-0.1-0.10.0-0.4-0.4-1.1-0.5-0.5
Glucose3.96.211.23.32.03.02.62.52.81.22.32.1
Heart weight2.74.17.92.82.42.62.62.11.4-1.01.31.0
Delay discount hyperbolic model param0.80.92.9-1.40.4-0.6-0.5-0.4-1.7-1.0-0.9-0.5
Intermittent access intake day 1-15 change0.10.30.8-0.6-0.9-0.4-0.9-0.6-0.2-0.0-0.4-0.4
Intermittent access intake escalation0.10.10.4-0.4-0.6-0.1-0.6-0.40.00.1-0.2-0.2
Intermittent access intake escalation 20.10.10.2-0.5-0.5-0.1-0.5-0.5-0.1-0.4-0.4-0.4
Intermitt. access day 1 inactive lever presses1.03.95.31.82.32.12.22.31.61.41.82.0
Intermitt. access day 15 inactive lever presses0.40.91.71.10.61.11.10.91.30.60.80.8
Intermitt. access escalation Index0.00.10.2-0.30.50.10.00.2-0.30.1-0.00.3
Intermittent access day 1 total infusions0.00.10.2-0.4-0.3-0.3-0.2-0.3-0.10.1-0.2-0.1
Intermittent access day 15 total infusions0.10.20.5-0.5-0.7-0.2-0.6-0.4-0.00.3-0.2-0.0
Intermittent access terminal intake (last 3 days)0.10.10.3-0.1-0.5-0.0-0.3-0.20.30.50.00.1
Intermittent access total infusions0.10.10.2-0.4-0.4-0.3-0.3-0.3-0.10.4-0.10.1
Intermittent access day 1 locomotion0.91.12.7-0.8-1.6-1.3-1.1-1.3-0.5-0.1-0.9-0.8
Intermittent access day 15 total locomotion0.40.71.90.90.10.60.50.61.11.40.90.9
Intermittent access total locomotion0.91.12.0-1.0-1.4-1.2-1.3-1.2-0.8-0.2-1.0-0.8
Intermittent access standard deviation0.40.71.50.9-0.10.90.20.61.21.20.90.9
Left kidney weight0.73.415.52.11.81.61.61.1-0.4-3.9-0.5-0.9
Right kidney weight0.94.222.51.91.91.41.31.0-0.9-4.7-1.1-1.2
Cocaine induced anxiety1.52.13.7-1.9-1.7-1.6-1.7-1.7-0.9-0.4-1.3-1.2
Post-drug Anxiety0.00.00.1-0.30.2-0.00.0-0.00.30.1-0.0-0.1
Baseline Anxiety3.23.75.22.22.22.12.32.11.71.01.81.7
Tail length0.52.03.21.21.41.81.71.41.30.81.31.6
Length with tail1.04.36.72.42.52.62.52.31.50.01.61.8
Length without tail2.16.810.73.33.13.12.93.12.00.32.12.2
Times rat made contact with spout0.10.10.70.30.30.30.30.1-0.3-0.9-0.1-0.2
Lifetime Intake0.10.20.4-0.6-0.6-0.5-0.5-0.5-0.30.2-0.3-0.1
Liver weight, left1.72.86.42.51.91.92.01.91.0-1.40.70.6
Liver weight, right0.61.15.70.71.00.30.50.5-1.0-2.4-0.7-0.8
Locomotor activity0.00.00.0-0.2-0.1-0.00.0-0.20.00.20.00.1
Locomotor testing distance0.61.22.0-1.4-1.1-1.1-1.1-1.2-1.1-0.8-1.0-0.9
Locomotor testing rearing0.20.40.9-0.6-1.0-0.5-0.8-0.8-0.3-0.0-0.5-0.6
Locomotion in novel chamber1.41.84.0-1.0-1.0-1.3-1.0-1.3-1.0-2.0-1.5-1.5
Locomotion in novel chamber post-restriction1.52.54.0-0.9-2.0-1.6-1.8-1.8-0.9-1.5-1.5-1.8
Fecal boli incidents, locomotor time 10.20.30.90.70.10.40.20.20.90.60.50.3
Change in fecal boli incidents, locomotor task0.20.20.8-0.20.50.10.20.2-0.8-0.9-0.3-0.2
Time >=10cm from walls, locomotor time 10.00.00.0-0.1-0.00.00.1-0.1-0.20.10.10.0
Bouts of movement, locomotor time 10.91.11.90.70.91.21.20.91.40.51.01.2
Total resting periods, locomotor time 10.40.40.80.30.60.90.80.60.90.10.50.7
Rest time, locomotor task time 11.01.32.7-1.2-0.5-0.8-1.1-0.9-1.1-1.6-1.4-1.2
Distance moved, locomotor task time 10.20.30.70.7-0.10.20.40.30.50.80.60.3
Vertical activity count, locomotor time 10.00.10.20.2-0.5-0.3-0.0-0.20.10.30.1-0.1
Time >=10cm from walls, locomotor time 20.10.20.60.00.0-0.3-0.0-0.1-0.7-0.8-0.4-0.4
Bouts of movement, locomotor time 20.00.00.1-0.4-0.3-0.0-0.3-0.2-0.20.1-0.10.1
Total resting periods, locomotor time 20.00.10.1-0.4-0.3-0.0-0.3-0.2-0.10.2-0.10.1
Rest time, locomotor task time 20.10.10.4-0.6-0.4-0.2-0.5-0.4-0.4-0.0-0.3-0.2
Distance moved, locomotor task time 20.00.10.20.0-0.1-0.3-0.0-0.1-0.1-0.5-0.2-0.3
Vertical activity count, locomotor time 20.00.10.3-0.00.0-0.40.1-0.1-0.0-0.5-0.2-0.2
Light reinforcement 10.81.93.0-1.3-1.1-1.3-1.1-1.3-1.5-1.7-1.4-1.4
Light reinforcement 20.40.60.9-0.9-0.7-0.7-0.7-0.9-0.8-0.7-0.6-0.7
Bone: marrow area0.30.61.51.20.90.90.80.90.4-0.60.30.3
Bone: maximum diameter3.36.210.33.22.62.92.92.62.40.62.12.2
Bone: maximum force0.50.93.01.21.20.80.61.1-0.0-1.7-0.2-0.1
Bone: maximum moment0.61.12.61.31.41.00.81.20.1-1.6-0.10.1
Mean time between licks in bursts0.51.33.00.41.71.11.41.30.50.91.11.3
Mean num. licks in bursts1.72.64.4-1.3-1.3-1.4-1.5-1.4-1.6-2.1-1.8-1.9
Cd content in liver2.73.03.6-1.7-1.6-1.6-1.8-1.9-1.8-1.5-1.7-1.8
Co content in liver1.72.03.8-1.1-1.1-1.4-1.4-1.2-1.2-1.9-1.6-1.6
Cu content in liver0.00.00.10.1-0.30.1-0.0-0.1-0.20.1-0.10.2
Fe content in liver2.63.25.61.62.41.82.02.11.01.01.71.8
K content in liver0.30.20.70.30.10.50.20.60.40.80.30.7
Mg content in liver0.20.21.0-0.2-1.0-0.2-0.6-0.5-0.00.2-0.4-0.2
Mn content in liver0.10.10.3-0.2-0.3-0.2-0.4-0.2-0.3-0.5-0.4-0.4
Na content in liver0.60.71.41.20.31.00.50.81.00.70.70.7
Rb content in liver0.10.20.40.5-0.10.40.30.30.50.60.30.6
Se content in liver0.00.00.1-0.20.20.0-0.10.10.00.40.10.2
Sr content in liver4.43.85.9-2.2-2.2-2.2-2.4-2.0-1.5-0.6-1.7-2.0
Zn content in liver2.12.43.8-1.6-1.9-1.5-1.8-1.8-1.3-0.8-1.6-1.3
Bone: minimum diameter1.52.85.82.41.82.11.91.81.4-0.31.21.2
Time in familiar zone, hab. session 10.20.20.70.9-0.30.40.3-0.10.7-0.20.1-0.3
Time in novel zone, hab. session 10.40.41.7-0.40.60.20.30.5-0.31.30.70.9
Total zone transitions, hab. session 10.20.30.5-0.1-0.7-0.6-0.4-0.7-0.2-0.5-0.5-0.6
Total locomotion distance, hab. session 10.20.30.60.40.80.50.70.40.20.50.70.6
Locomotion velocity, hab. session 10.10.20.60.20.80.30.50.3-0.10.10.40.3
Time in familiar zone, hab. session 22.22.34.71.02.21.51.41.80.91.41.71.5
Time in novel zone, hab. session 21.51.53.0-0.6-1.7-1.0-1.1-1.7-0.9-1.1-1.2-1.2
Total zone transitions, hab. session 20.20.20.5-0.0-0.5-0.4-0.3-0.7-0.4-0.7-0.4-0.6
Total locomotion distance, hab. session 20.10.10.30.50.50.40.50.1-0.2-0.40.30.0
Locomotion velocity, hab. session 20.10.10.30.60.50.50.50.1-0.1-0.40.30.0
Novel to familiar place preference ratio0.10.10.30.30.20.40.60.10.00.10.30.5
Novelty place preference0.10.10.20.10.10.30.4-0.0-0.10.10.20.4
Time in novel zone, NPP test0.40.40.70.60.50.70.80.40.10.50.70.8
Total zone transitions, NPP test0.50.82.6-0.5-0.1-0.7-0.4-0.7-1.0-1.6-0.9-1.0
Total locomotion distance, NPP test0.30.41.5-0.40.1-0.4-0.2-0.5-1.0-1.2-0.6-0.6
Locomotion velocity, NPP test0.91.23.5-1.0-0.3-1.0-0.7-1.0-1.1-1.9-1.2-1.1
Intraocular pressure1.72.43.41.61.61.41.61.91.11.41.61.8
Delta distance traveled before/after self-admin0.10.10.40.10.20.20.30.40.40.60.40.4
Delta ambulatory time before/after self-admin0.30.40.60.40.60.40.70.70.50.80.60.7
Parametrial fat weight8.720.534.45.95.75.55.65.23.2-1.43.12.9
Pavlov. Cond. lever latency0.50.62.00.20.40.50.40.60.71.40.81.0
Pavlov. Cond. magazine entry latency0.20.20.50.50.70.40.60.4-0.2-0.70.10.1
Pavlov. Cond. change in total contacts0.40.41.01.00.70.91.00.50.2-0.70.40.2
Pavlov. Cond. index score0.10.20.90.40.40.30.50.2-0.1-0.9-0.1-0.2
Pavlov. Cond. latency score0.10.21.00.30.30.10.30.1-0.2-1.0-0.2-0.4
Pavlov. Cond. lever contacts0.10.10.70.5-0.10.10.2-0.10.0-0.8-0.2-0.4
Pavlov. Cond. magazine entry number0.20.20.4-0.5-0.6-0.5-0.6-0.40.10.6-0.1-0.0
Pavlov. Cond. intertrial magazine entries0.40.53.1-0.10.3-0.20.1-0.1-0.6-1.8-0.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.80.50.60.40.60.3-0.1-0.90.0-0.1
Pavlov. Cond. response bias0.10.10.90.30.10.00.1-0.0-0.3-0.9-0.3-0.4
Pavlov. Cond. lever latency1.72.33.5-1.6-1.8-1.7-1.7-1.9-0.8-0.7-1.4-1.7
Pavlov. Cond. magazine entry latency1.11.31.81.21.21.01.11.21.11.11.41.1
Pavlov. Cond. change in total contacts1.01.52.11.31.31.41.31.30.81.01.31.5
Pavlov. Cond. index score1.41.82.61.41.61.41.51.60.90.91.31.4
Pavlov. Cond. latency score1.21.62.31.31.51.31.41.50.80.81.21.3
Pavlov. Cond. lever contacts1.01.42.21.31.31.31.31.50.60.51.01.3
Pavlov. Cond. magazine entry number0.50.71.0-1.0-0.8-0.7-0.7-0.9-0.7-0.8-0.9-0.8
Pavlov. Cond. intertrial magazine entries0.20.31.80.10.30.20.10.3-0.4-1.3-0.6-0.4
Pavlov. Cond. lever-magazine prob. diff.1.01.41.91.31.31.11.31.40.80.91.21.3
Pavlov. Cond. response bias1.72.43.11.61.71.61.71.81.00.91.51.7
Time in closed arm before self-admin0.00.00.1-0.2-0.1-0.2-0.1-0.10.00.1-0.1-0.2
Time in closed arm after self-admin2.22.43.3-1.7-1.3-1.6-1.8-1.5-1.6-1.2-1.5-1.6
Time in open arm before self-admin0.20.20.7-0.5-0.8-0.4-0.5-0.7-0.10.3-0.20.1
Time in open arm after self-admin3.13.45.51.51.41.92.01.52.31.91.92.0
Bone: periosteal estimation1.12.45.22.31.91.91.71.71.1-1.20.70.7
Bone: periosteal perimeter2.64.510.03.22.02.62.32.32.2-0.11.51.5
Bone: post-yield work0.40.62.60.41.60.50.51.1-0.3-0.60.30.3
Progressive ratio test 1 active lever presses0.30.41.0-0.7-1.0-0.8-0.8-0.8-0.10.1-0.5-0.4
Progressive ratio test 1 breakpoint0.30.41.0-0.7-1.0-0.7-0.9-0.80.00.1-0.5-0.4
Progressive ratio test 1 inactive lever presses0.30.50.90.50.50.40.60.60.91.00.70.8
Progressive ratio test 2 active lever presses0.00.10.20.0-0.5-0.1-0.4-0.1-0.00.2-0.10.0
Progressive ratio test 2 breakpoint0.00.00.20.1-0.4-0.0-0.4-0.0-0.00.2-0.00.1
Progressive ratio test 2 inactive lever presses0.10.20.50.10.70.40.40.70.00.40.30.6
Incentive Sensitization - Responses0.10.20.40.70.20.60.20.50.10.20.30.4
Incentive Sensitization - Breakpoint0.20.20.40.70.30.70.20.70.10.30.40.6
Sum of active levers in priming session hrs 5-60.90.91.40.81.11.21.01.10.50.40.81.1
Progressive ratio0.30.51.5-0.7-1.0-0.6-0.7-0.6-0.31.2-0.10.1
Food seeking constrained by brief footshock0.40.63.6-0.4-0.6-0.4-0.2-0.10.41.90.50.5
Seeking ratio, punishment vs. effort0.00.10.1-0.2-0.0-0.3-0.2-0.1-0.0-0.3-0.3-0.4
Retroperitoneal fat weight8.937.867.38.28.17.17.47.24.1-2.24.13.6
Reaction time number correct0.20.41.01.0-0.10.70.70.30.90.50.60.7
Reaction time mean minus median0.10.20.50.1-0.7-0.4-0.7-0.2-0.20.4-0.2-0.3
Reaction time mean minus median AUC0.30.92.8-0.2-1.7-0.9-1.4-1.0-0.2-0.1-0.7-0.9
Reaction time num false alarms1.11.54.0-0.8-0.5-1.0-1.0-0.8-1.5-2.0-1.4-1.4
Reaction time num false alarms AUC0.91.33.8-0.6-0.7-0.9-1.0-0.9-1.2-1.9-1.3-1.4
Reaction time trials correct on left0.20.41.01.0-0.10.70.70.30.90.50.60.7
Reaction time trials on left0.30.51.01.0-0.00.80.70.41.00.50.60.7
Reaction time mean0.30.61.8-0.2-1.2-0.8-1.0-0.4-0.11.30.0-0.2
Reaction time mean AUC0.40.71.8-0.4-1.3-0.9-1.2-0.5-0.31.3-0.2-0.3
Median of all reaction times0.40.61.8-0.4-1.3-0.9-1.0-0.5-0.01.4-0.0-0.2
Reaction time omissions0.71.11.90.81.00.90.81.11.11.41.21.1
Reaction time false alarm rate1.01.43.5-0.8-0.3-1.0-1.0-0.7-1.4-1.9-1.2-1.4
Reaction time premature initiation rate0.10.10.5-0.3-0.1-0.7-0.4-0.2-0.0-0.3-0.4-0.4
Reaction time premature initiations0.00.00.20.2-0.1-0.2-0.00.00.4-0.1-0.1-0.1
Std. dev. reaction times0.10.10.50.3-0.4-0.2-0.60.2-0.00.70.1-0.1
Reaction time trials completed0.30.51.01.0-0.00.80.70.41.00.50.60.7
Reaction time trials AUC0.20.41.01.0-0.00.80.70.40.90.30.50.6
Run reversals in cocaine runway, females0.70.71.60.60.30.50.60.51.31.30.90.9
Run reversals in cocaine runway, males1.41.42.0-1.3-1.2-1.2-1.4-1.2-1.2-0.8-1.1-1.1
Latency to leave start box in cocaine runway1.31.43.30.90.01.21.00.61.61.81.31.2
Latency to leave start box in cocaine runway, F0.81.01.50.80.51.20.90.81.01.21.11.0
Latency to leave start box in cocaine runway, M0.60.51.90.6-0.70.40.5-0.21.40.90.60.4
Std. dev. time between licks in bursts0.10.20.5-0.60.7-0.20.00.3-0.60.40.10.2
Total sessions with >9 infusions0.50.61.2-0.7-1.0-1.1-0.8-0.8-0.70.1-0.6-0.5
Short access day 1 total inactive lever presses0.40.51.0-0.01.00.30.90.8-0.20.90.60.8
Short access day 10 total inactive lever presses0.10.40.90.40.90.40.30.7-0.8-0.9-0.2-0.1
Short access day 1 total infusions0.20.30.5-0.7-0.3-0.7-0.4-0.4-0.7-0.0-0.4-0.3
Short access day 10 total infusions1.01.32.3-1.4-1.5-1.3-1.1-1.5-0.6-0.3-1.0-0.9
Short access total infusions0.70.91.4-1.2-1.1-1.2-0.9-1.1-0.8-0.3-0.8-0.7
Short access day 1 locomotion0.10.10.3-0.0-0.5-0.40.1-0.2-0.20.3-0.1-0.0
Short access day 10 total locomotion0.40.71.7-0.7-1.3-1.0-1.0-1.1-0.1-0.1-0.7-0.7
Short access total locomotion1.82.24.5-1.3-2.1-1.9-1.6-1.8-1.0-0.4-1.4-1.3
One hour access (0.3 mA shock)1.01.12.00.70.91.00.91.10.81.41.21.4
Compulsive drug intake1.01.22.61.01.61.11.31.40.40.31.01.0
One hour access (shock baseline)0.10.20.5-0.7-0.6-0.4-0.5-0.5-0.30.5-0.2-0.0
Social response proportion0.60.72.2-0.5-0.4-0.8-0.2-0.6-0.9-1.5-1.0-0.9
Social responses0.91.22.31.51.21.11.51.10.90.00.90.7
Social time0.10.10.40.6-0.20.40.5-0.10.40.30.40.2
Soleus weight0.20.63.30.9-0.40.20.1-0.10.2-1.8-0.7-0.7
Bone: stiffness0.20.41.20.50.80.40.10.8-0.5-1.1-0.3-0.2
Tibialis anterior weight0.10.30.50.60.50.70.50.70.20.30.30.7
Time to tail flick, vehicle, before self-admin0.10.10.10.30.40.30.40.4-0.00.10.30.3
Time to tail flick, vehicle, after self-admin0.10.10.40.30.20.30.20.30.60.40.30.2
Time to tail flick, test, before self-admin2.93.05.3-1.5-2.3-1.9-1.7-2.0-1.5-0.9-1.6-1.8
Time to tail flick, test, after self-admin0.60.61.50.21.20.70.80.90.40.80.70.9
Delta time to tail flick, vehicle, before/after SA1.11.12.81.30.61.10.90.81.71.01.00.8
Delta time to tail flick, test, before/after SA1.41.44.20.62.01.31.21.40.80.40.91.2
Tibia length0.00.10.30.50.20.20.20.10.3-0.5-0.0-0.0
Ambulatory time before self-admin2.74.05.4-2.0-2.3-2.1-2.3-2.3-1.7-1.4-1.9-1.9
Ambulatory time after self-admin1.11.32.3-1.4-1.5-1.4-1.2-1.4-0.9-0.2-0.9-0.9
Bone: tissue strength0.50.50.90.50.40.70.60.60.71.00.80.8
Total heroin consumption2.63.16.52.61.32.01.61.72.40.51.61.3
Bone: trabecular number0.91.53.71.31.91.31.31.90.2-0.10.80.9
Bone: trabecular spacing0.20.31.1-1.0-0.3-0.5-0.4-0.7-0.30.80.10.2
Bone: trabecular thickness3.34.18.02.82.22.42.22.51.6-0.21.41.5
Bone: trabecular tissue density0.50.72.1-1.5-0.7-1.0-0.9-0.9-0.9-0.3-0.8-0.4
Water consumed over 24 hours0.50.61.3-0.5-0.9-0.4-0.5-0.9-0.8-1.1-0.8-0.9
Number of responses in last shaping day0.30.30.6-0.5-0.7-0.8-0.6-0.5-0.70.0-0.4-0.4