Hub : Genes

Lmbr1l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Lmbr1l 0.34 0.17 0.0e+00 0.31 0.31 0.3 0.3 1.1e-34 6.6e-35 2.5e-34 2.3e-34
2 Brain alternative polyA XM_039078924.1 0.06 0.05 2.5e-06 0.05 0.05 0.05 0.05 3.3e-05 1.9e-05 3.2e-05 4.0e-05
3 OFC mRNA stability Lmbr1l 0.17 0.14 1.1e-03 0.09 0.1 0.09 0.09 3.3e-03 2.8e-03 3.3e-03 4.4e-03
4 IL gene expression Lmbr1l 0.15 0.11 1.7e-03 0.11 0.1 0.1 0.1 1.6e-03 2.4e-03 1.7e-03 1.9e-03
5 PL gene expression Lmbr1l 0.02 0.02 5.0e-03 0.03 0.02 0.03 0.03 4.6e-04 6.2e-03 7.5e-04 7.2e-04
6 PL mRNA stability Lmbr1l 0.06 0.05 2.7e-06 0.04 0.05 0.05 0.05 1.2e-05 1.9e-06 7.4e-06 7.1e-06
7 Brain gene expression Lmbr1l 0.13 0.08 6.5e-15 0.16 0.16 0.16 0.16 4.1e-15 2.9e-14 6.8e-15 6.5e-15
8 Brain isoform ratio XM_039078925.1 0.03 0.03 1.8e-03 0.02 0.02 0.01 0.01 7.1e-03 1.2e-02 1.8e-02 2.0e-02
9 Brain mRNA stability Lmbr1l 0.11 0.1 6.0e-09 0.09 0.09 0.09 0.1 4.6e-09 4.7e-09 1.0e-08 2.8e-09
10 LHb mRNA stability Lmbr1l 0.18 0.13 4.2e-04 0.12 0.12 0.1 0.11 8.0e-04 9.9e-04 2.1e-03 1.3e-03
11 Adipose gene expression Lmbr1l 0.06 0.06 1.2e-06 0.04 0.03 0.03 0.03 3.2e-05 1.8e-04 9.8e-05 2.2e-04
12 NAcc mRNA stability Lmbr1l 0.04 0.04 4.4e-05 0.03 0.03 0.03 0.03 1.1e-04 1.5e-04 5.9e-04 1.6e-04
13 Eye mRNA stability Lmbr1l 0.36 0.22 1.2e-04 0.24 0.28 0.29 0.27 1.1e-04 2.8e-05 2.3e-05 4.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density10.317.218.84.3-4.2-4.2-4.3-4.3-4.2-4.14.1-4.04.0-4.14.13.9
Area under the delay curve0.90.91.31.0-1.0-1.0-1.0-1.0-1.0-0.80.8-1.00.9-1.11.10.7
BMI with tail4.414.117.53.7-3.8-3.8-3.6-3.6-3.9-3.63.6-3.64.1-4.24.23.0
BMI without tail0.10.10.6-0.20.10.20.30.3-0.00.4-0.40.20.5-0.50.5-0.8
Body weight6.225.930.45.1-5.1-5.1-4.9-4.9-5.2-4.84.8-5.05.5-5.55.54.5
Weight adjusted by age2.12.33.31.5-1.5-1.5-1.4-1.4-1.6-1.41.4-1.61.8-1.61.61.4
Bone surface12.121.322.74.7-4.7-4.7-4.8-4.8-4.7-4.64.6-4.64.5-4.54.54.5
Bone volume9.015.316.84.0-4.0-4.0-4.1-4.1-4.0-3.93.9-3.93.7-3.73.73.9
Breakpoint value in progressive ratio session0.20.30.40.5-0.5-0.5-0.4-0.4-0.5-0.60.6-0.50.6-0.60.60.4
Number of licking bursts0.30.40.7-0.70.70.70.80.80.60.8-0.80.5-0.10.2-0.2-0.7
Context. condit. distance diff. score0.20.30.60.5-0.5-0.5-0.5-0.5-0.5-0.40.4-0.50.8-0.60.60.5
Locomotion velocity, session 11.11.21.8-1.11.11.11.11.11.11.0-1.01.0-1.31.4-1.4-0.7
Locomotion distance, session 13.13.95.7-1.91.91.91.91.92.01.7-1.72.0-2.42.3-2.3-1.9
Locomotion velocity, session 20.30.41.2-0.50.50.50.40.40.50.5-0.50.4-1.10.9-0.9-0.2
Locomotion distance, session 22.53.55.4-1.81.81.81.71.71.81.8-1.81.8-2.32.1-2.1-1.7
Locomotion velocity, session 34.24.95.6-2.22.22.22.12.12.22.4-2.42.1-2.32.2-2.2-2.1
Locomotion distance, session 35.25.77.0-2.42.42.42.22.22.42.4-2.42.3-2.42.6-2.6-2.1
Stereotopy head waving bouts, day 31.21.42.01.2-1.2-1.2-1.3-1.3-1.2-1.01.0-1.30.8-1.11.11.4
Stereotopy head waving duration, day 30.50.71.00.8-0.9-0.8-0.9-0.9-0.8-0.80.8-0.90.2-0.70.71.0
Locomotion velocity, session 70.20.20.4-0.50.50.50.40.40.50.6-0.60.4-0.40.5-0.5-0.4
Locomotion distance, session 71.72.12.8-1.51.51.51.41.41.51.7-1.71.4-1.11.5-1.5-1.3
Stereotopy head waving bouts, day 71.01.11.51.0-1.1-1.0-1.1-1.1-1.1-0.90.9-1.20.9-1.21.21.0
Stereotopy head waving duration, day 71.21.51.91.2-1.2-1.2-1.2-1.2-1.3-1.21.2-1.31.1-1.41.41.1
Locomotion velocity, session 80.00.00.10.0-0.1-0.10.00.0-0.1-0.10.10.0-0.3-0.00.0-0.0
Locomotion distance, session 81.21.82.1-1.31.31.31.31.31.31.4-1.41.4-1.41.4-1.4-1.4
Degree of sensitization distance0.50.50.90.7-0.7-0.7-0.7-0.7-0.7-0.60.6-0.70.9-0.90.90.6
Degree of sensitization stereotypy0.20.20.40.4-0.4-0.4-0.3-0.3-0.5-0.40.4-0.60.5-0.60.60.4
Conditioned locomotion0.10.10.30.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.4-0.0-0.10.10.6
Cocaine response after cond. corrected0.00.00.1-0.10.10.10.00.00.10.1-0.10.3-0.20.1-0.1-0.3
Cocaine response after cond. not corrected0.60.70.9-0.80.80.80.70.70.80.8-0.81.0-0.90.9-0.9-0.9
Cocaine response before conditioning3.34.04.4-2.12.12.12.02.02.12.0-2.01.8-2.02.0-2.0-1.7
Saline control response0.10.20.20.4-0.4-0.4-0.5-0.5-0.4-0.50.5-0.40.4-0.40.40.4
Bone: connectivity density7.511.712.83.5-3.5-3.5-3.6-3.6-3.5-3.43.4-3.33.2-3.43.43.2
Bone: cortical apparent density0.20.30.4-0.60.60.60.50.50.70.6-0.60.6-0.40.6-0.6-0.4
Bone: cortical area9.614.415.83.8-3.9-3.8-3.8-3.8-3.9-3.63.6-3.94.0-3.93.93.6
Bone: cortical porosity0.80.92.0-0.90.90.90.80.81.00.7-0.70.7-1.11.4-1.4-0.3
Bone: cortical porosity1.21.32.8-1.11.11.11.01.01.31.0-1.00.9-1.31.7-1.7-0.5
Bone: cortical thickness3.35.56.72.4-2.4-2.4-2.3-2.3-2.6-2.02.0-2.42.5-2.62.62.0
Bone: cortical thickness0.10.20.50.3-0.4-0.3-0.3-0.3-0.4-0.10.1-0.40.7-0.70.70.1
Bone: cortical tissue density0.30.40.6-0.70.70.70.60.60.80.6-0.60.7-0.60.7-0.7-0.5
Condit. Reinf. active minus inactive responses0.10.10.4-0.20.20.20.20.20.20.2-0.20.4-0.60.4-0.4-0.3
Condit. Reinf. active-inactive response ratio0.20.20.40.5-0.5-0.5-0.6-0.6-0.5-0.60.6-0.40.1-0.30.30.5
Condit. Reinf. active responses0.60.81.5-0.80.80.80.80.80.80.8-0.80.9-1.20.9-0.9-0.9
Condit. Reinf. inactive responses2.83.33.5-1.81.81.81.91.91.81.9-1.91.7-1.81.7-1.7-1.8
Incentive salience index mean0.00.00.00.1-0.2-0.2-0.1-0.1-0.2-0.10.1-0.1-0.0-0.10.1-0.0
Condit. Reinf. lever presses0.10.10.20.4-0.4-0.4-0.3-0.3-0.5-0.30.3-0.40.3-0.40.40.3
Condit. Reinf. active minus inactive responses0.00.00.0-0.10.10.10.10.10.20.1-0.10.00.10.0-0.0-0.1
Condit. Reinf. active-inactive response ratio0.30.30.4-0.60.60.60.60.60.60.5-0.50.6-0.50.5-0.5-0.6
Condit. Reinf. active responses0.10.20.3-0.50.50.50.40.40.50.5-0.50.4-0.20.4-0.4-0.4
Condit. Reinf. inactive responses0.50.70.8-0.90.90.90.80.80.90.9-0.90.7-0.60.8-0.8-0.6
Condit. Reinf. lever presses0.00.00.10.00.00.0-0.1-0.10.0-0.00.0-0.00.3-0.10.10.1
Condit. Reinf. lever reinforcers received0.40.60.8-0.90.90.90.80.80.90.8-0.80.7-0.50.8-0.8-0.7
Conditioned reinforcement - actives1.71.72.1-1.31.31.31.51.51.31.5-1.51.1-1.11.1-1.1-1.4
Conditioned reinforcement - inactives2.22.53.0-1.61.51.61.71.71.51.7-1.71.5-1.51.4-1.4-1.6
Conditioned locomotion0.40.50.8-0.70.70.70.90.90.70.9-0.90.5-0.40.6-0.6-0.6
Patch foraging indifference point 0 sec2.23.53.9-1.91.91.92.02.01.91.9-1.91.9-1.71.8-1.8-1.9
Patch foraging indifference point AUC0.20.20.5-0.50.50.50.50.50.50.5-0.50.4-0.20.2-0.2-0.7
Delay disc. indifference point, 0s delay1.11.21.51.1-1.2-1.1-1.1-1.1-1.2-1.01.0-1.20.9-1.21.20.9
Delay disc. indifference point, 16s delay0.90.91.20.9-1.0-1.0-0.8-0.8-1.0-0.80.8-1.01.0-1.11.10.8
Delay disc. indifference point, 2s delay1.41.51.81.3-1.3-1.3-1.4-1.4-1.2-1.31.3-1.21.0-1.11.11.2
Delay disc. indifference point, 24s delay1.41.41.81.2-1.2-1.2-1.1-1.1-1.2-1.11.1-1.21.3-1.31.31.1
Delay disc. indifference point, 4s delay0.30.30.50.5-0.5-0.5-0.6-0.6-0.5-0.40.4-0.40.4-0.70.70.3
Delay disc. indifference point, 8s delay2.52.63.11.6-1.6-1.6-1.5-1.5-1.7-1.51.5-1.71.6-1.81.81.4
Indifference point function ln k3.85.36.02.4-2.3-2.4-2.4-2.4-2.3-2.32.3-2.32.0-2.12.12.5
Indifference point function log k3.85.36.02.4-2.3-2.4-2.4-2.4-2.3-2.32.3-2.32.0-2.12.12.5
Patch foraging total patch changes 0 sec2.13.43.7-1.91.91.91.91.91.81.9-1.91.8-1.71.7-1.7-1.9
Patch foraging total patch changes 12 sec2.02.63.4-1.71.71.71.81.81.61.6-1.61.6-1.21.3-1.3-1.8
Patch foraging total patch changes 18 sec3.95.15.6-2.42.32.42.32.32.32.3-2.32.2-2.02.0-2.0-2.4
Patch foraging total patch changes 24 sec2.02.42.7-1.61.61.61.61.61.61.6-1.61.5-1.31.4-1.4-1.6
Patch foraging total patch changes 6 sec2.43.64.0-2.01.92.02.02.01.92.0-2.01.8-1.61.7-1.7-2.0
Patch foraging time to switch 0 sec2.23.43.8-1.91.91.91.81.81.91.8-1.81.9-1.81.9-1.9-1.6
Patch foraging water rate 0 sec2.84.55.22.1-2.2-2.2-2.1-2.1-2.2-2.02.0-2.12.0-2.32.31.8
Patch foraging water rate 12 sec3.65.56.22.4-2.4-2.4-2.5-2.5-2.4-2.32.3-2.42.2-2.22.22.5
Patch foraging water rate 18 sec0.20.30.50.6-0.6-0.6-0.5-0.5-0.6-0.50.5-0.60.7-0.60.60.5
Patch foraging water rate 24 sec3.14.34.82.1-2.1-2.1-2.2-2.2-2.1-2.02.0-2.12.0-2.02.02.1
Patch foraging water rate 6 sec3.65.26.02.4-2.4-2.3-2.4-2.4-2.4-2.22.2-2.42.1-2.12.12.4
Seeking ratio, delayed vs. immediate footshock0.30.30.40.6-0.6-0.6-0.5-0.5-0.6-0.50.5-0.60.5-0.60.60.5
Distance traveled before self-admin1.11.21.2-1.11.11.11.11.11.11.1-1.11.1-1.11.0-1.0-1.1
Distance traveled after self-admin0.20.20.5-0.40.40.40.40.40.40.4-0.40.4-0.70.4-0.4-0.4
Extensor digitorum longus weight4.015.721.43.9-3.9-4.0-3.6-3.6-4.1-3.73.7-3.94.6-4.34.33.5
Bone: elastic displacement4.55.16.7-2.22.22.22.22.22.32.1-2.12.3-2.62.4-2.4-1.9
Bone: elastic work0.00.10.20.1-0.0-0.1-0.2-0.20.1-0.20.2-0.0-0.40.3-0.30.4
Bone: endosteal estimation7.917.319.24.2-4.2-4.2-4.2-4.2-4.1-4.24.2-4.24.1-3.93.94.4
Bone: endosteal perimeter6.914.417.53.8-3.8-3.8-3.7-3.7-3.8-3.73.7-3.94.2-3.73.73.8
Epididymis fat weight0.10.30.50.6-0.6-0.6-0.7-0.7-0.6-0.50.5-0.40.6-0.50.50.5
Delta time in closed arm before/after self-admin0.30.30.40.5-0.5-0.5-0.5-0.5-0.5-0.70.7-0.50.4-0.40.40.6
Delta time in open arm before/after self-admin4.64.45.0-2.12.12.12.12.12.12.1-2.12.1-2.22.1-2.1-2.1
Diff in mean of infusions in LGA sessions1.51.71.81.3-1.3-1.3-1.3-1.3-1.3-1.41.4-1.21.1-1.31.31.2
Delay discount exponential model param0.80.81.2-0.90.90.90.90.91.00.8-0.80.9-0.91.1-1.1-0.7
Extinction: sum of active levers before priming0.40.40.60.7-0.7-0.7-0.7-0.7-0.6-0.80.8-0.60.5-0.50.50.6
Active lever presses in extinction session 60.50.50.50.7-0.7-0.7-0.6-0.6-0.7-0.70.7-0.70.5-0.60.60.7
Bone: final force10.116.217.14.1-4.1-4.1-4.1-4.1-4.1-4.04.0-4.03.8-3.93.93.9
Bone: final moment10.617.218.24.3-4.3-4.3-4.3-4.3-4.2-4.24.2-4.13.8-3.93.94.1
Food consumed during 24 hour testing period1.72.12.31.5-1.5-1.5-1.5-1.5-1.5-1.41.4-1.41.4-1.41.41.2
Glucose0.10.10.60.2-0.2-0.2-0.1-0.1-0.3-0.20.2-0.20.8-0.50.5-0.1
Heart weight0.00.10.20.3-0.3-0.3-0.2-0.2-0.2-0.30.3-0.20.1-0.00.00.4
Delay discount hyperbolic model param0.80.81.2-0.90.90.90.90.91.00.8-0.80.9-0.81.1-1.1-0.7
Intermittent access intake day 1-15 change1.41.41.6-1.31.31.31.31.31.21.3-1.31.1-0.71.1-1.1-1.2
Intermittent access intake escalation1.01.01.1-1.11.11.11.11.11.01.1-1.10.9-0.50.9-0.9-1.0
Intermittent access intake escalation 21.61.61.8-1.31.31.31.41.41.31.4-1.41.2-0.81.1-1.1-1.2
Intermitt. access day 1 inactive lever presses2.83.03.6-1.71.71.71.61.61.81.6-1.61.8-1.81.9-1.9-1.6
Intermitt. access day 15 inactive lever presses1.31.41.7-1.21.21.21.21.21.21.2-1.21.3-1.21.2-1.2-1.1
Intermitt. access escalation Index0.20.20.3-0.40.50.40.30.30.50.3-0.30.5-0.20.6-0.6-0.3
Intermittent access day 1 total infusions1.31.51.7-1.21.21.21.31.31.21.3-1.31.2-1.11.3-1.3-1.1
Intermittent access day 15 total infusions2.73.03.6-1.81.81.81.91.91.71.9-1.91.7-1.21.7-1.7-1.6
Intermittent access terminal intake (last 3 days)3.03.33.7-1.91.91.91.91.91.81.9-1.91.7-1.41.9-1.9-1.6
Intermittent access total infusions2.83.13.5-1.81.81.81.91.91.71.9-1.91.7-1.31.8-1.8-1.6
Intermittent access day 1 locomotion0.91.01.3-1.01.01.01.01.01.01.0-1.01.0-0.81.1-1.1-0.8
Intermittent access day 15 total locomotion1.71.82.5-1.41.41.41.61.61.31.6-1.61.1-0.71.2-1.2-1.2
Intermittent access total locomotion3.43.94.7-2.02.02.02.22.22.02.2-2.21.8-1.41.9-1.9-1.8
Intermittent access standard deviation0.50.60.7-0.80.80.80.80.80.70.8-0.80.7-0.50.7-0.7-0.8
Left kidney weight0.30.91.11.0-1.0-1.0-1.0-1.0-1.1-1.01.0-1.00.6-0.90.90.9
Right kidney weight2.77.69.22.7-2.8-2.8-2.6-2.6-2.8-2.72.7-2.82.7-3.03.02.5
Cocaine induced anxiety1.11.32.21.1-1.1-1.1-1.1-1.1-1.1-1.11.1-1.21.5-1.01.01.3
Post-drug Anxiety5.15.76.42.4-2.4-2.4-2.4-2.4-2.4-2.42.4-2.42.5-2.22.22.5
Baseline Anxiety0.90.91.11.0-1.0-1.0-1.0-1.0-1.1-1.01.0-0.80.8-0.90.90.9
Tail length0.10.30.6-0.60.60.60.60.60.50.8-0.80.5-0.20.2-0.2-0.8
Length with tail1.97.17.42.7-2.7-2.7-2.7-2.7-2.7-2.62.6-2.72.7-2.72.72.5
Length without tail7.616.617.54.2-4.1-4.2-4.1-4.1-4.2-4.14.1-4.14.0-3.93.94.1
Times rat made contact with spout0.10.10.3-0.30.30.30.40.40.20.4-0.40.4-0.20.2-0.2-0.5
Lifetime Intake2.62.93.6-1.81.81.81.91.91.61.9-1.91.6-1.21.6-1.6-1.6
Liver weight, left1.93.14.51.7-1.7-1.8-1.6-1.6-1.8-1.71.7-1.72.1-1.91.91.4
Liver weight, right1.52.53.51.6-1.6-1.6-1.6-1.6-1.6-1.51.5-1.51.9-1.51.51.4
Locomotor activity1.21.92.5-1.41.41.41.41.41.31.6-1.61.2-1.21.3-1.3-1.3
Locomotor testing distance3.05.06.0-2.32.32.32.22.22.22.4-2.42.0-2.12.2-2.2-2.0
Locomotor testing rearing2.23.54.4-2.02.02.01.91.91.92.1-2.11.7-1.51.7-1.7-1.7
Locomotion in novel chamber0.50.71.00.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.80.8-1.01.00.6
Locomotion in novel chamber post-restriction0.00.00.10.1-0.1-0.1-0.2-0.2-0.1-0.20.2-0.20.0-0.10.10.1
Fecal boli incidents, locomotor time 12.32.52.8-1.51.51.51.61.61.51.6-1.61.6-1.61.5-1.5-1.7
Change in fecal boli incidents, locomotor task1.41.31.61.2-1.2-1.2-1.2-1.2-1.1-1.31.3-1.10.8-0.90.91.3
Time >=10cm from walls, locomotor time 10.20.20.20.4-0.4-0.4-0.4-0.4-0.4-0.50.5-0.40.4-0.30.30.4
Bouts of movement, locomotor time 10.00.00.10.1-0.1-0.10.10.1-0.1-0.10.10.0-0.40.1-0.10.1
Total resting periods, locomotor time 10.20.30.8-0.40.40.40.60.60.40.4-0.40.6-0.90.6-0.6-0.4
Rest time, locomotor task time 10.40.40.7-0.60.60.60.70.70.60.6-0.60.8-0.80.6-0.6-0.7
Distance moved, locomotor task time 10.10.10.30.2-0.2-0.2-0.3-0.3-0.1-0.20.2-0.20.5-0.10.10.4
Vertical activity count, locomotor time 11.41.51.81.2-1.2-1.2-1.2-1.2-1.2-1.11.1-1.31.3-1.11.11.3
Time >=10cm from walls, locomotor time 20.80.81.1-0.80.80.80.80.80.81.1-1.10.8-1.10.9-0.9-0.9
Bouts of movement, locomotor time 22.52.73.21.7-1.7-1.7-1.6-1.6-1.7-1.61.6-1.61.6-1.81.81.5
Total resting periods, locomotor time 22.93.13.71.8-1.8-1.8-1.7-1.7-1.8-1.81.8-1.71.7-1.91.91.6
Rest time, locomotor task time 20.00.00.10.2-0.1-0.2-0.1-0.1-0.2-0.30.3-0.00.3-0.20.20.1
Distance moved, locomotor task time 20.10.10.3-0.30.30.30.20.20.30.3-0.30.3-0.40.6-0.60.0
Vertical activity count, locomotor time 20.00.00.20.1-0.1-0.1-0.1-0.1-0.20.1-0.1-0.40.3-0.20.20.2
Light reinforcement 12.74.95.5-2.32.32.42.32.32.32.3-2.32.0-1.72.1-2.1-2.0
Light reinforcement 20.91.21.4-1.21.21.11.21.21.11.2-1.21.0-0.90.9-0.9-1.1
Bone: marrow area7.816.918.94.1-4.1-4.1-4.2-4.2-4.1-4.24.2-4.24.1-3.83.84.3
Bone: maximum diameter3.87.09.12.6-2.6-2.6-2.5-2.5-2.7-2.32.3-2.83.0-3.03.02.4
Bone: maximum force14.525.126.45.1-5.1-5.1-5.1-5.1-5.0-5.15.1-5.04.8-4.74.75.1
Bone: maximum moment15.126.027.95.2-5.2-5.2-5.3-5.3-5.1-5.25.2-5.04.8-4.64.65.3
Mean time between licks in bursts0.20.20.8-0.20.30.30.10.10.40.3-0.30.3-0.70.9-0.90.2
Mean num. licks in bursts0.00.10.30.1-0.1-0.1-0.1-0.1-0.0-0.20.20.2-0.50.4-0.40.0
Cd content in liver0.70.81.0-0.90.90.90.90.90.81.0-1.00.8-0.50.8-0.8-0.9
Co content in liver0.60.71.2-0.90.80.81.11.10.61.1-1.10.7-0.30.3-0.3-1.1
Cu content in liver0.60.71.00.9-0.9-0.9-0.7-0.7-1.0-0.90.9-0.70.8-0.50.51.0
Fe content in liver0.40.51.2-0.70.70.70.80.80.50.9-0.90.8-0.10.2-0.2-1.1
K content in liver0.20.20.50.4-0.5-0.5-0.3-0.3-0.5-0.40.4-0.40.5-0.70.70.2
Mg content in liver0.00.00.2-0.10.10.10.10.10.00.2-0.20.0-0.2-0.30.3-0.4
Mn content in liver0.10.10.20.3-0.3-0.3-0.4-0.4-0.2-0.20.2-0.2-0.1-0.10.10.3
Na content in liver0.00.10.1-0.20.20.20.30.30.20.2-0.20.3-0.10.0-0.0-0.3
Rb content in liver0.40.51.0-0.70.70.70.80.80.60.9-0.90.7-0.40.3-0.3-1.0
Se content in liver0.60.81.1-0.90.90.90.90.90.81.0-1.00.9-0.80.8-0.8-0.9
Sr content in liver0.30.30.70.5-0.5-0.5-0.5-0.5-0.6-0.30.3-0.60.8-0.50.50.5
Zn content in liver1.92.12.6-1.51.51.51.61.61.41.6-1.61.4-1.21.3-1.3-1.5
Bone: minimum diameter9.217.118.64.2-4.2-4.2-4.1-4.1-4.2-4.04.0-4.24.3-4.04.04.2
Time in familiar zone, hab. session 10.40.40.9-0.50.50.50.50.50.50.5-0.50.7-0.90.8-0.8-0.4
Time in novel zone, hab. session 10.40.40.70.5-0.5-0.5-0.5-0.5-0.5-0.50.5-0.70.8-0.80.80.5
Total zone transitions, hab. session 10.40.60.8-0.70.70.70.70.70.70.8-0.80.7-0.90.8-0.8-0.7
Total locomotion distance, hab. session 10.00.00.10.1-0.1-0.1-0.2-0.2-0.0-0.10.1-0.0-0.30.2-0.20.2
Locomotion velocity, hab. session 10.00.00.10.2-0.2-0.2-0.3-0.3-0.1-0.20.2-0.2-0.10.0-0.00.2
Time in familiar zone, hab. session 20.30.30.40.6-0.6-0.6-0.6-0.6-0.5-0.60.6-0.40.2-0.50.50.4
Time in novel zone, hab. session 20.20.20.3-0.50.50.50.50.50.50.5-0.50.3-0.10.5-0.5-0.2
Total zone transitions, hab. session 20.40.51.0-0.60.60.60.60.60.60.7-0.70.7-1.00.8-0.8-0.7
Total locomotion distance, hab. session 20.10.20.6-0.30.30.30.10.10.30.3-0.30.4-0.80.7-0.7-0.2
Locomotion velocity, hab. session 20.10.10.4-0.10.10.1-0.1-0.10.20.2-0.20.3-0.60.5-0.5-0.1
Novel to familiar place preference ratio1.92.03.31.3-1.3-1.4-1.3-1.3-1.3-1.41.4-1.31.8-1.51.51.3
Novelty place preference1.41.52.61.1-1.1-1.1-1.1-1.1-1.1-1.21.2-1.11.6-1.31.31.1
Time in novel zone, NPP test1.21.22.31.0-1.0-1.0-1.0-1.0-1.0-1.11.1-1.01.5-1.21.21.1
Total zone transitions, NPP test1.52.13.0-1.41.41.41.41.41.31.4-1.41.5-1.71.6-1.6-1.5
Total locomotion distance, NPP test1.82.43.6-1.51.51.51.31.31.61.4-1.41.6-1.91.9-1.9-1.4
Locomotion velocity, NPP test1.01.42.3-1.11.11.11.01.01.11.1-1.11.2-1.51.4-1.4-1.0
Intraocular pressure7.710.711.3-3.33.33.33.33.33.33.3-3.33.3-3.33.1-3.1-3.4
Delta distance traveled before/after self-admin0.10.10.10.3-0.3-0.3-0.3-0.3-0.3-0.20.2-0.30.1-0.20.20.3
Delta ambulatory time before/after self-admin0.00.00.00.1-0.1-0.1-0.0-0.0-0.1-0.00.0-0.10.1-0.10.10.1
Parametrial fat weight2.24.25.6-2.12.12.12.12.12.01.9-1.92.2-2.11.9-1.9-2.4
Pavlov. Cond. lever latency0.10.10.40.4-0.3-0.4-0.4-0.4-0.2-0.60.6-0.2-0.0-0.20.20.5
Pavlov. Cond. magazine entry latency0.00.00.00.0-0.0-0.0-0.0-0.0-0.0-0.10.10.00.10.1-0.1-0.0
Pavlov. Cond. change in total contacts0.00.00.20.1-0.1-0.1-0.0-0.0-0.20.1-0.1-0.10.5-0.00.00.1
Pavlov. Cond. index score0.00.00.30.0-0.1-0.1-0.0-0.0-0.20.1-0.1-0.20.5-0.20.2-0.1
Pavlov. Cond. latency score0.00.00.2-0.0-0.00.00.00.0-0.20.2-0.2-0.10.4-0.20.2-0.2
Pavlov. Cond. lever contacts0.50.61.0-0.80.80.80.90.90.61.0-1.00.7-0.30.6-0.6-1.0
Pavlov. Cond. magazine entry number0.00.00.10.2-0.2-0.2-0.2-0.2-0.1-0.20.2-0.2-0.1-0.10.10.3
Pavlov. Cond. intertrial magazine entries0.40.51.6-0.60.60.60.60.60.60.5-0.50.7-1.30.9-0.9-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.4-0.4-0.4-0.3-0.3-0.5-0.30.3-0.40.8-0.50.50.2
Pavlov. Cond. response bias0.10.10.2-0.30.30.30.30.30.20.3-0.30.3-0.00.3-0.3-0.4
Pavlov. Cond. lever latency0.00.00.10.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.10.2-0.20.3
Pavlov. Cond. magazine entry latency1.11.31.51.2-1.2-1.2-1.1-1.1-1.1-1.21.2-1.21.2-1.01.01.2
Pavlov. Cond. change in total contacts1.42.03.31.3-1.4-1.4-1.3-1.3-1.5-1.31.3-1.31.8-1.61.61.1
Pavlov. Cond. index score0.50.71.10.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.81.0-0.90.90.7
Pavlov. Cond. latency score0.60.71.00.8-0.8-0.8-0.8-0.8-0.9-0.90.9-0.81.0-0.90.90.7
Pavlov. Cond. lever contacts0.10.10.3-0.40.40.40.40.40.40.4-0.40.4-0.10.2-0.2-0.5
Pavlov. Cond. magazine entry number2.32.83.5-1.71.71.71.61.61.71.7-1.71.7-1.91.7-1.7-1.7
Pavlov. Cond. intertrial magazine entries5.47.07.8-2.62.62.62.62.62.62.7-2.72.6-2.82.6-2.6-2.6
Pavlov. Cond. lever-magazine prob. diff.1.01.21.71.1-1.1-1.1-1.0-1.0-1.1-1.11.1-1.01.3-1.11.11.0
Pavlov. Cond. response bias0.00.00.1-0.10.10.10.10.10.00.0-0.00.10.3-0.10.1-0.1
Time in closed arm before self-admin1.61.82.51.3-1.3-1.3-1.2-1.2-1.3-1.31.3-1.41.6-1.51.51.3
Time in closed arm after self-admin0.80.81.10.9-0.9-0.9-0.9-0.9-0.8-1.01.0-0.91.0-0.90.91.0
Time in open arm before self-admin0.70.81.10.9-0.9-0.9-0.9-0.9-0.8-0.90.9-0.81.0-0.70.71.0
Time in open arm after self-admin0.30.30.6-0.50.50.50.60.60.50.6-0.60.6-0.80.6-0.6-0.6
Bone: periosteal estimation12.124.926.55.0-5.0-5.0-5.0-5.0-5.1-4.84.8-5.15.2-5.05.04.9
Bone: periosteal perimeter10.217.118.84.2-4.2-4.2-4.1-4.1-4.2-4.04.0-4.24.3-4.14.14.0
Bone: post-yield work8.811.912.93.5-3.5-3.5-3.5-3.5-3.4-3.53.5-3.53.4-3.33.33.6
Progressive ratio test 1 active lever presses4.74.95.6-2.32.32.32.42.42.22.4-2.42.0-1.82.2-2.2-2.1
Progressive ratio test 1 breakpoint4.34.55.3-2.22.22.22.32.32.12.3-2.31.9-1.72.0-2.0-2.0
Progressive ratio test 1 inactive lever presses3.84.14.7-2.12.02.02.22.22.02.2-2.21.9-1.82.0-2.0-1.9
Progressive ratio test 2 active lever presses2.42.63.2-1.71.71.71.81.81.61.8-1.81.6-1.11.4-1.4-1.5
Progressive ratio test 2 breakpoint3.13.54.1-1.91.91.92.02.01.92.0-2.01.9-1.41.7-1.7-1.8
Progressive ratio test 2 inactive lever presses2.73.13.6-1.81.81.81.91.91.81.9-1.91.8-1.41.7-1.7-1.6
Incentive Sensitization - Responses0.00.00.10.0-0.1-0.00.10.1-0.10.1-0.1-0.10.3-0.40.4-0.0
Incentive Sensitization - Breakpoint0.00.00.1-0.10.10.10.20.20.00.2-0.20.00.2-0.20.2-0.1
Sum of active levers in priming session hrs 5-60.00.00.1-0.10.20.10.20.20.20.1-0.10.2-0.20.3-0.3-0.0
Progressive ratio0.00.00.1-0.20.20.20.20.20.20.3-0.30.1-0.00.2-0.2-0.2
Food seeking constrained by brief footshock0.40.50.7-0.70.70.70.80.80.60.7-0.70.7-0.50.8-0.8-0.6
Seeking ratio, punishment vs. effort0.00.00.0-0.10.10.10.10.10.1-0.00.00.2-0.10.2-0.2-0.1
Retroperitoneal fat weight0.51.72.0-1.31.31.31.31.31.21.3-1.31.3-1.01.3-1.3-1.4
Reaction time number correct1.52.23.91.5-1.5-1.5-1.7-1.7-1.4-1.51.5-1.60.9-1.01.02.0
Reaction time mean minus median8.210.812.4-3.33.43.43.43.43.33.2-3.23.4-3.23.0-3.0-3.5
Reaction time mean minus median AUC5.87.68.4-2.82.82.82.82.82.82.7-2.72.9-2.72.6-2.6-2.8
Reaction time num false alarms1.62.12.5-1.51.51.51.41.41.51.4-1.41.4-1.51.6-1.6-1.3
Reaction time num false alarms AUC2.33.13.5-1.81.81.81.71.71.91.7-1.71.8-1.81.9-1.9-1.6
Reaction time trials correct on left1.52.23.91.5-1.5-1.5-1.7-1.7-1.4-1.51.5-1.60.9-1.01.02.0
Reaction time trials on left1.21.73.31.4-1.3-1.3-1.5-1.5-1.2-1.31.3-1.40.7-0.80.81.8
Reaction time mean0.70.91.8-1.01.01.01.01.00.91.0-1.01.1-0.80.6-0.6-1.3
Reaction time mean AUC0.40.51.2-0.70.70.70.70.70.60.8-0.80.9-0.60.4-0.4-1.1
Median of all reaction times0.00.00.20.1-0.1-0.1-0.1-0.1-0.10.0-0.00.00.3-0.40.4-0.3
Reaction time omissions10.113.814.3-3.73.73.73.73.73.83.7-3.73.7-3.73.8-3.8-3.6
Reaction time false alarm rate2.63.64.1-2.02.02.02.02.01.91.9-1.92.0-1.71.8-1.8-2.0
Reaction time premature initiation rate6.58.710.8-3.13.03.03.23.22.93.2-3.22.8-2.32.5-2.5-3.3
Reaction time premature initiations3.04.25.1-2.12.12.12.12.12.02.3-2.31.8-1.71.9-1.9-2.1
Std. dev. reaction times6.18.610.3-3.03.03.03.03.02.92.9-2.93.1-2.82.6-2.6-3.2
Reaction time trials completed1.21.73.31.4-1.3-1.3-1.5-1.5-1.2-1.31.3-1.40.7-0.80.81.8
Reaction time trials AUC1.92.74.71.7-1.7-1.7-1.9-1.9-1.6-1.71.7-1.81.0-1.11.12.2
Run reversals in cocaine runway, females0.00.00.0-0.00.00.00.10.10.10.1-0.10.00.2-0.10.1-0.1
Run reversals in cocaine runway, males1.61.51.6-1.21.21.21.21.21.21.2-1.21.2-1.31.2-1.2-1.2
Latency to leave start box in cocaine runway0.00.00.1-0.10.10.10.10.10.10.1-0.10.10.0-0.10.1-0.3
Latency to leave start box in cocaine runway, F1.71.92.1-1.41.41.41.31.31.41.4-1.41.3-1.21.4-1.4-1.3
Latency to leave start box in cocaine runway, M2.12.02.71.4-1.4-1.4-1.4-1.4-1.5-1.41.4-1.31.4-1.61.61.1
Std. dev. time between licks in bursts1.01.21.8-1.21.21.21.11.11.11.3-1.30.9-0.81.0-1.0-0.9
Total sessions with >9 infusions1.01.11.6-1.11.11.11.31.30.91.3-1.30.8-0.50.6-0.6-1.1
Short access day 1 total inactive lever presses1.51.72.0-1.31.31.31.41.41.21.4-1.41.3-0.81.1-1.1-1.3
Short access day 10 total inactive lever presses0.20.20.4-0.40.50.50.40.40.60.4-0.40.7-0.50.5-0.5-0.4
Short access day 1 total infusions0.10.10.2-0.30.30.30.40.40.20.4-0.40.20.00.1-0.1-0.2
Short access day 10 total infusions1.01.11.6-1.11.11.11.31.31.01.3-1.30.9-0.70.9-0.9-1.1
Short access total infusions0.60.61.1-0.80.80.81.01.00.71.0-1.00.6-0.20.5-0.5-0.8
Short access day 1 locomotion0.10.10.3-0.40.40.40.50.50.30.5-0.50.30.10.1-0.1-0.4
Short access day 10 total locomotion0.10.20.2-0.40.40.40.40.40.40.4-0.40.3-0.30.4-0.4-0.3
Short access total locomotion0.50.50.7-0.70.70.70.90.90.70.9-0.90.5-0.30.5-0.5-0.7
One hour access (0.3 mA shock)0.30.40.6-0.60.60.60.80.80.50.8-0.80.4-0.10.5-0.5-0.5
Compulsive drug intake1.01.01.31.1-1.0-1.1-1.2-1.2-1.0-1.21.2-0.80.5-1.01.00.9
One hour access (shock baseline)0.20.30.5-0.50.50.50.70.70.40.7-0.70.20.20.4-0.4-0.3
Social response proportion0.10.10.2-0.40.40.40.50.50.30.5-0.50.4-0.20.2-0.2-0.5
Social responses7.69.811.2-3.23.23.23.33.33.23.3-3.33.1-2.62.8-2.8-3.3
Social time0.00.00.1-0.00.00.00.20.20.00.0-0.00.2-0.20.1-0.1-0.3
Soleus weight0.61.72.31.3-1.3-1.3-1.3-1.3-1.3-1.31.3-1.31.5-1.31.31.2
Bone: stiffness17.327.328.45.3-5.3-5.3-5.3-5.3-5.2-5.25.2-5.25.2-5.15.15.1
Tibialis anterior weight0.93.28.31.6-1.7-1.7-1.4-1.4-1.9-1.41.4-1.72.9-2.32.31.2
Time to tail flick, vehicle, before self-admin0.90.91.6-0.91.01.00.90.91.00.7-0.71.0-1.31.0-1.0-0.9
Time to tail flick, vehicle, after self-admin0.20.20.40.5-0.5-0.5-0.5-0.5-0.5-0.40.4-0.60.6-0.40.40.6
Time to tail flick, test, before self-admin0.40.40.9-0.50.50.50.60.60.60.5-0.50.7-1.00.7-0.7-0.6
Time to tail flick, test, after self-admin0.20.20.30.5-0.4-0.5-0.4-0.4-0.4-0.50.5-0.50.5-0.40.40.5
Delta time to tail flick, vehicle, before/after SA0.40.40.70.6-0.6-0.6-0.6-0.6-0.7-0.40.4-0.70.9-0.60.60.6
Delta time to tail flick, test, before/after SA0.20.20.50.4-0.4-0.4-0.4-0.4-0.4-0.40.4-0.50.7-0.50.50.5
Tibia length7.521.124.54.6-4.6-4.6-4.5-4.5-4.7-4.24.2-4.64.9-5.05.04.2
Ambulatory time before self-admin4.04.24.3-2.02.12.02.02.02.12.1-2.12.1-2.12.0-2.0-2.0
Ambulatory time after self-admin1.82.02.1-1.41.41.41.41.41.41.5-1.51.4-1.41.2-1.2-1.4
Bone: tissue strength1.21.11.91.1-1.1-1.1-1.2-1.2-1.0-1.21.2-1.00.7-0.70.71.4
Total heroin consumption2.02.33.11.5-1.5-1.5-1.4-1.4-1.5-1.51.5-1.61.8-1.51.51.6
Bone: trabecular number6.510.111.93.3-3.3-3.3-3.4-3.4-3.2-3.23.2-3.02.8-3.13.12.9
Bone: trabecular spacing2.33.03.7-1.81.81.81.91.91.71.8-1.81.5-1.61.8-1.8-1.4
Bone: trabecular thickness0.10.10.2-0.30.30.30.30.30.30.5-0.50.4-0.30.3-0.3-0.4
Bone: trabecular tissue density0.10.10.2-0.30.30.30.20.20.30.3-0.30.1-0.20.4-0.40.1
Water consumed over 24 hours0.00.00.10.1-0.1-0.1-0.2-0.2-0.1-0.20.2-0.20.00.1-0.10.2
Number of responses in last shaping day0.10.10.60.1-0.1-0.1-0.0-0.0-0.2-0.00.0-0.20.8-0.30.30.3