Hub : Traits : body_g :

chr7:26,902,995-30,734,621

Best TWAS P=2.954577e-20 · Best GWAS P=5.722316e-25 conditioned to NaN

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 Adipose Elk3 gene expression ENSRNOG00000004367 0.11 0.05 blup 2579 0.05 2.5e-06 -7.5 7.7 1.2e-14 -0.48 0.74 0.26 FALSE
2 Adipose Hal gene expression ENSRNOG00000004502 0.03 0.00 blup 2432 0.01 6.9e-02 -8.5 -8.5 1.5e-17 0.53 0.28 0.38 FALSE
3 Adipose Vezt gene expression ENSRNOG00000006514 0.11 0.08 top1 1 0.08 3.2e-09 -6.3 -6.3 2.5e-10 0.67 1.00 0.00 FALSE
4 Adipose Ndufa12 gene expression ENSRNOG00000007407 0.34 0.19 lasso 16 0.20 1.0e-21 -7.3 -7.4 1.7e-13 0.73 1.00 0.00 FALSE
5 Adipose Tmcc3 gene expression ENSRNOG00000007713 0.11 0.02 blup 2421 0.04 1.1e-05 -6.9 -5.8 8.2e-09 0.42 0.91 0.02 FALSE
6 Adipose Fgd6 gene expression ENSRNOG00000054515 0.07 0.01 enet 82 0.04 1.4e-05 -6.7 5.9 3.7e-09 -0.50 0.75 0.10 FALSE
7 Adipose Tmcc3 isoform ratio ENSRNOT00000010316 0.16 0.02 top1 1 0.02 1.4e-03 5.3 5.3 9.2e-08 -0.15 0.07 0.03 FALSE
8 Adipose Cep83 intron excision ratio chr7:29322957:29325469 0.03 0.01 blup 2703 0.02 1.8e-03 -6.9 -6.7 2.4e-11 0.74 0.55 0.32 FALSE
9 Adipose Vezt mRNA stability ENSRNOG00000006514 0.07 0.04 blup 2570 0.06 5.0e-07 -8.0 -8.3 1.4e-16 0.71 0.74 0.26 FALSE
10 BLA AABR07056633.1 alternative TSS ENSRNOT00000094647 0.19 0.12 lasso 27 0.12 3.4e-07 -5.3 5.3 1.5e-07 -0.26 1.00 0.00 FALSE
11 BLA Ntn4 gene expression ENSRNOG00000005573 0.06 0.02 blup 2475 0.03 8.1e-03 1.2 7.3 3.3e-13 -0.60 0.50 0.28 FALSE
12 BLA Vezt gene expression ENSRNOG00000006514 0.32 0.25 enet 97 0.30 1.1e-16 -6.8 -7.9 3.2e-15 0.68 0.44 0.56 FALSE
13 BLA Ndufa12 gene expression ENSRNOG00000007407 0.09 0.01 enet 13 0.03 1.1e-02 -8.5 -5.8 5.3e-09 -0.28 0.31 0.49 FALSE
14 BLA Metap2 gene expression ENSRNOG00000021881 0.08 0.07 top1 1 0.07 1.9e-04 -8.8 8.8 1.0e-18 -0.73 0.08 0.20 FALSE
15 BLA Mir331 gene expression ENSRNOG00000035543 0.06 0.04 blup 2366 0.06 5.1e-04 -7.3 9.1 8.9e-20 -0.76 0.39 0.60 FALSE
16 BLA Fgd6 gene expression ENSRNOG00000054515 0.11 0.13 top1 1 0.13 2.7e-07 -7.9 -7.9 2.5e-15 0.78 0.92 0.01 FALSE
17 BLA Tmcc3 isoform ratio ENSRNOT00000102476 0.10 0.02 blup 2424 0.04 3.2e-03 -7.8 -7.1 1.1e-12 0.64 0.48 0.40 TRUE
18 BLA AABR07056633.1 isoform ratio ENSRNOT00000114083 0.18 0.06 top1 1 0.06 6.5e-04 -5.4 -5.4 6.4e-08 0.41 0.14 0.04 FALSE
19 BLA Lta4h intron excision ratio chr7:27997602:27999743 0.07 0.01 blup 2332 0.02 2.6e-02 -5.7 -6.8 7.7e-12 0.53 0.70 0.16 FALSE
20 BLA Vezt intron excision ratio chr7:28557619:28560958 0.07 0.01 blup 2571 0.01 6.6e-02 1.4 7.3 2.9e-13 -0.71 0.46 0.27 FALSE
21 BLA Tmcc3 intron excision ratio chr7:29100427:29159418 0.12 0.10 lasso 10 0.11 1.0e-06 -2.7 5.4 6.8e-08 -0.66 0.76 0.22 FALSE
22 BLA Tmcc3 intron excision ratio chr7:29133627:29159418 0.07 0.02 blup 2424 0.04 4.3e-03 -7.6 -8.0 8.8e-16 0.71 0.40 0.43 FALSE
23 BLA Vezt mRNA stability ENSRNOG00000006514 0.40 0.42 top1 1 0.42 4.0e-24 -8.6 8.6 1.1e-17 -0.78 0.35 0.65 FALSE
24 BLA Plxnc1 mRNA stability ENSRNOG00000007970 0.11 0.11 top1 1 0.11 3.0e-06 -7.8 7.8 4.3e-15 -0.79 0.36 0.03 FALSE
25 Brain AABR07056633.1 alternative TSS ENSRNOT00000094647 0.06 0.02 top1 1 0.02 3.3e-03 -5.3 5.3 1.3e-07 -0.36 0.14 0.03 FALSE
26 Brain AABR07056633.1 alternative TSS ENSRNOT00000094647 0.06 0.02 top1 1 0.02 4.8e-03 -5.3 5.3 1.3e-07 -0.36 0.12 0.03 FALSE
27 Brain Lta4h gene expression ENSRNOG00000004494 0.05 0.04 top1 1 0.04 9.1e-05 -8.3 8.3 8.1e-17 -0.61 0.11 0.04 FALSE
28 Brain Vezt gene expression ENSRNOG00000006514 0.24 0.22 blup 2571 0.23 1.2e-20 -9.1 -8.4 5.4e-17 0.70 0.12 0.88 FALSE
29 Brain Ndufa12 gene expression ENSRNOG00000007407 0.49 0.32 blup 2574 0.34 6.1e-32 -7.3 -7.5 7.4e-14 0.69 1.00 0.00 FALSE
30 Brain Plxnc1 gene expression ENSRNOG00000007970 0.05 0.02 blup 3131 0.04 6.3e-05 -2.8 -5.6 2.2e-08 0.71 0.83 0.15 FALSE
31 Brain Socs2 gene expression ENSRNOG00000008965 0.22 0.09 enet 118 0.11 5.0e-10 -7.8 6.4 1.5e-10 -0.42 0.99 0.01 FALSE
32 Brain Metap2 gene expression ENSRNOG00000021881 0.04 0.01 blup 2312 0.01 1.4e-02 -8.3 7.6 2.9e-14 -0.49 0.32 0.42 FALSE
33 Brain Ccdc38 gene expression ENSRNOG00000021892 0.10 0.06 blup 2464 0.07 1.9e-07 2.3 6.2 6.0e-10 -0.36 0.99 0.00 FALSE
34 Brain Fgd6 gene expression ENSRNOG00000054515 0.16 0.23 top1 1 0.23 8.6e-21 -8.2 -8.2 3.1e-16 0.74 0.94 0.06 FALSE
35 Brain Tmcc3 isoform ratio ENSRNOT00000102476 0.03 0.01 blup 2424 0.01 3.4e-02 -3.1 -6.0 2.2e-09 0.70 0.83 0.05 FALSE
36 Brain AABR07056633.1 isoform ratio ENSRNOT00000094647 0.03 0.00 blup 2953 0.01 7.7e-02 1.7 5.7 9.4e-09 -0.38 0.52 0.09 FALSE
37 Brain Lta4h intron excision ratio chr7:27997602:27999743 0.04 0.02 top1 1 0.02 4.8e-03 -6.9 -6.9 4.0e-12 0.54 0.10 0.03 FALSE
38 Brain Tmcc3 intron excision ratio chr7:29133627:29159418 0.05 0.01 blup 2424 0.02 7.7e-03 -3.5 -6.0 1.8e-09 0.66 0.90 0.06 FALSE
39 Brain Lta4h mRNA stability ENSRNOG00000004494 0.05 0.02 blup 2332 0.03 9.8e-04 -8.3 7.9 3.0e-15 -0.63 0.46 0.48 FALSE
40 Brain Vezt mRNA stability ENSRNOG00000006514 0.20 0.20 lasso 28 0.20 1.6e-18 -8.1 8.2 2.6e-16 -0.70 0.33 0.67 FALSE
41 Eye Lta4h gene expression ENSRNOG00000004494 0.41 0.04 lasso 24 0.07 3.0e-02 -8.1 8.1 5.3e-16 -0.63 0.26 0.41 FALSE
42 Eye Fgd6 gene expression ENSRNOG00000054515 0.52 0.13 blup 2560 0.15 2.3e-03 -7.3 -8.2 3.0e-16 0.78 0.43 0.17 FALSE
43 Eye Elk3 isoform ratio ENSRNOT00000005911 0.36 0.01 blup 2579 0.10 1.2e-02 -8.2 -8.3 1.3e-16 0.58 0.26 0.45 FALSE
44 IL Vezt gene expression ENSRNOG00000006514 0.29 0.20 lasso 4 0.26 7.2e-07 -7.3 -7.5 4.4e-14 0.67 0.41 0.58 FALSE
45 IL Tmcc3 gene expression ENSRNOG00000007713 0.46 0.16 top1 1 0.16 1.2e-04 5.6 5.6 2.6e-08 0.50 0.13 0.05 TRUE
46 IL Vezt mRNA stability ENSRNOG00000006514 0.23 0.06 blup 2568 0.10 2.4e-03 -7.4 8.4 3.2e-17 -0.76 0.52 0.36 FALSE
47 LHb Nr2c1 alternative polyA ENSRNOT00000009578 0.20 0.19 top1 1 0.19 2.6e-05 -6.1 6.1 8.0e-10 -0.63 0.14 0.05 FALSE
48 LHb Nr2c1 alternative polyA ENSRNOT00000089228 0.32 0.21 top1 1 0.21 8.9e-06 -6.1 -6.1 8.0e-10 0.62 0.15 0.05 FALSE
49 LHb Ntn4 gene expression ENSRNOG00000005573 0.21 0.04 blup 2473 0.06 1.6e-02 -8.5 -8.2 2.0e-16 0.62 0.35 0.44 FALSE
50 LHb Plxnc1 gene expression ENSRNOG00000007970 0.41 0.09 blup 3118 0.22 7.2e-06 -3.5 -6.8 1.3e-11 0.74 0.67 0.30 FALSE
51 LHb Cdk17 isoform ratio ENSRNOT00000109496 0.18 0.05 blup 2984 0.11 1.4e-03 -4.9 6.7 2.3e-11 -0.45 0.50 0.26 TRUE
52 LHb Vezt mRNA stability ENSRNOG00000006514 0.40 0.20 enet 84 0.21 1.1e-05 -8.2 8.8 1.3e-18 -0.70 0.33 0.67 FALSE
53 Liver Amdhd1 gene expression ENSRNOG00000005266 0.37 0.31 lasso 40 0.34 1.7e-39 -6.1 -7.5 8.3e-14 0.55 1.00 0.00 FALSE
54 Liver Ntn4 gene expression ENSRNOG00000005573 0.10 0.05 blup 2475 0.06 4.3e-07 -8.0 -9.2 4.5e-20 0.64 0.44 0.56 FALSE
55 Liver Vezt gene expression ENSRNOG00000006514 0.14 0.12 enet 322 0.14 1.7e-15 -6.5 -5.4 8.2e-08 0.48 1.00 0.00 FALSE
56 Liver Nr2c1 gene expression ENSRNOG00000006983 0.04 0.03 enet 37 0.03 2.0e-04 -2.8 -5.5 4.7e-08 0.66 0.90 0.08 FALSE
57 Liver Ndufa12 gene expression ENSRNOG00000007407 0.42 0.43 enet 320 0.46 1.8e-56 -7.3 -7.2 7.0e-13 0.71 1.00 0.00 FALSE
58 Liver Ccdc38 gene expression ENSRNOG00000021892 0.32 0.35 top1 1 0.35 1.8e-40 -6.1 6.1 1.3e-09 -0.54 1.00 0.00 FALSE
59 Liver Lta4h mRNA stability ENSRNOG00000004494 0.11 0.11 top1 1 0.11 6.2e-12 -8.3 8.3 1.3e-16 -0.59 0.84 0.16 FALSE
60 Liver Amdhd1 mRNA stability ENSRNOG00000005266 0.24 0.22 top1 1 0.22 6.1e-24 -6.1 -6.1 1.3e-09 0.55 1.00 0.00 FALSE
61 Liver Snrpf mRNA stability ENSRNOG00000005556 0.03 0.02 top1 1 0.02 1.4e-03 -6.4 -6.4 2.1e-10 0.56 0.08 0.03 FALSE
62 Liver Tmcc3 mRNA stability ENSRNOG00000007713 0.17 0.05 lasso 13 0.05 1.3e-06 5.3 -5.9 3.2e-09 0.38 0.98 0.02 FALSE
63 NAcc Vezt gene expression ENSRNOG00000006514 0.23 0.14 blup 2568 0.19 5.5e-05 -8.6 -8.7 2.2e-18 0.71 0.53 0.44 FALSE
64 NAcc Tmcc3 gene expression ENSRNOG00000007713 0.33 0.07 lasso 12 0.11 2.0e-03 -7.4 -6.5 1.1e-10 0.71 0.39 0.32 FALSE
65 NAcc2 AABR07056633.1 alternative TSS ENSRNOT00000094647 0.05 0.05 top1 1 0.05 1.4e-03 -5.2 5.2 1.6e-07 -0.39 0.13 0.04 FALSE
66 NAcc2 AABR07056633.1 alternative TSS ENSRNOT00000104436 0.05 0.05 top1 1 0.04 1.8e-03 -5.2 -5.2 1.6e-07 0.39 0.13 0.04 FALSE
67 NAcc2 AABR07056633.1 alternative TSS ENSRNOT00000094647 0.06 0.05 top1 1 0.05 7.5e-04 -5.2 5.2 1.6e-07 -0.39 0.15 0.04 FALSE
68 NAcc2 AABR07056633.1 alternative TSS ENSRNOT00000104436 0.06 0.05 top1 1 0.05 9.2e-04 -5.2 -5.2 1.6e-07 0.39 0.15 0.04 FALSE
69 NAcc2 Elk3 gene expression ENSRNOG00000004367 0.05 0.07 top1 1 0.07 9.7e-05 -5.9 5.9 4.8e-09 -0.42 0.14 0.04 TRUE
70 NAcc2 Vezt gene expression ENSRNOG00000006514 0.08 0.08 top1 1 0.08 4.2e-05 -6.9 -6.9 4.9e-12 0.75 0.46 0.02 FALSE
71 NAcc2 Plxnc1 gene expression ENSRNOG00000007970 0.10 0.09 top1 1 0.09 1.5e-05 -7.7 -7.7 1.1e-14 0.80 0.63 0.01 FALSE
72 NAcc2 Ccdc38 gene expression ENSRNOG00000021892 0.16 0.04 blup 2464 0.12 4.0e-07 2.0 5.2 2.0e-07 -0.33 0.87 0.13 FALSE
73 NAcc2 Mir331 gene expression ENSRNOG00000035543 0.04 0.03 enet 75 0.04 2.6e-03 -8.5 8.6 1.0e-17 -0.67 0.47 0.44 TRUE
74 NAcc2 Tmcc3 isoform ratio ENSRNOT00000102476 0.04 0.03 top1 1 0.03 7.9e-03 -8.0 -8.0 1.3e-15 0.80 0.10 0.04 FALSE
75 NAcc2 Tmcc3 intron excision ratio chr7:29133627:29159418 0.06 0.07 top1 1 0.07 8.3e-05 -7.8 -7.8 7.9e-15 0.80 0.12 0.04 FALSE
76 NAcc2 Lta4h mRNA stability ENSRNOG00000004494 0.08 0.09 top1 1 0.09 1.0e-05 -8.7 8.7 2.8e-18 -0.60 0.10 0.52 FALSE
77 NAcc2 Vezt mRNA stability ENSRNOG00000006514 0.09 0.04 blup 2571 0.06 4.2e-04 -6.9 8.4 5.2e-17 -0.73 0.56 0.44 FALSE
78 OFC Vezt gene expression ENSRNOG00000006514 0.38 0.25 enet 117 0.28 3.0e-07 -8.3 -8.6 5.5e-18 0.71 0.35 0.65 FALSE
79 OFC Ndufa12 gene expression ENSRNOG00000007407 0.19 0.16 top1 1 0.16 1.1e-04 -8.9 -8.9 4.7e-19 0.77 0.07 0.55 FALSE
80 OFC Vezt mRNA stability ENSRNOG00000006514 0.24 0.12 blup 2568 0.14 3.2e-04 -8.2 9.1 9.3e-20 -0.76 0.34 0.64 FALSE
81 PL Vezt gene expression ENSRNOG00000006514 0.26 0.17 top1 1 0.17 6.3e-05 -7.3 -7.3 2.7e-13 0.74 0.18 0.05 FALSE
82 PL Tmcc3 gene expression ENSRNOG00000007713 0.58 0.20 lasso 19 0.24 1.8e-06 5.2 6.2 4.5e-10 -0.33 0.79 0.03 FALSE
83 PL Fgd6 gene expression ENSRNOG00000054515 0.42 0.00 lasso 14 0.03 5.6e-02 -6.4 -5.4 5.6e-08 0.41 0.29 0.11 FALSE
84 PL Vezt mRNA stability ENSRNOG00000006514 0.21 0.09 top1 1 0.09 3.2e-03 -8.4 8.4 4.4e-17 -0.77 0.13 0.05 FALSE
85 PL Plxnc1 mRNA stability ENSRNOG00000007970 0.38 0.14 lasso 7 0.18 4.3e-05 -3.5 7.4 1.0e-13 -0.70 0.74 0.20 FALSE
86 PL2 AABR07056633.1 alternative TSS ENSRNOT00000094647 0.09 0.07 top1 1 0.07 7.6e-05 -5.3 5.3 1.5e-07 -0.38 0.27 0.03 FALSE
87 PL2 AABR07056633.1 alternative TSS ENSRNOT00000104436 0.09 0.07 top1 1 0.07 7.8e-05 -5.3 -5.3 1.5e-07 0.38 0.27 0.03 FALSE
88 PL2 AABR07056633.1 alternative TSS ENSRNOT00000094647 0.09 0.07 top1 1 0.07 9.6e-05 -5.3 5.3 1.5e-07 -0.39 0.34 0.03 FALSE
89 PL2 AABR07056633.1 alternative TSS ENSRNOT00000104436 0.09 0.07 top1 1 0.07 9.7e-05 -5.3 -5.3 1.5e-07 0.39 0.34 0.03 FALSE
90 PL2 Vezt gene expression ENSRNOG00000006514 0.57 0.40 blup 2571 0.45 1.0e-26 -7.0 -7.8 5.8e-15 0.72 0.45 0.55 FALSE
91 PL2 Ndufa12 gene expression ENSRNOG00000007407 0.09 0.06 blup 2574 0.07 7.5e-05 -8.5 -9.0 1.9e-19 0.77 0.59 0.41 FALSE
92 PL2 Socs2 gene expression ENSRNOG00000008965 0.09 0.04 top1 1 0.04 3.6e-03 -8.4 8.4 3.9e-17 -0.74 0.13 0.04 FALSE
93 PL2 Fgd6 gene expression ENSRNOG00000054515 0.08 0.05 blup 2571 0.05 9.5e-04 -7.2 -9.1 7.9e-20 0.79 0.61 0.38 FALSE
94 PL2 Socs2 intron excision ratio chr7:29987686:30043188 0.06 0.01 enet 66 0.01 5.2e-02 -4.5 -7.0 3.5e-12 0.55 0.48 0.31 TRUE
95 PL2 Socs2 intron excision ratio chr7:30015321:30041048 0.06 0.00 blup 3386 0.03 8.8e-03 -3.9 -9.2 3.0e-20 0.69 0.45 0.28 TRUE
96 PL2 Vezt mRNA stability ENSRNOG00000006514 0.30 0.40 lasso 7 0.42 2.2e-24 -8.5 9.1 1.1e-19 -0.79 0.49 0.51 FALSE
97 PL2 Plxnc1 mRNA stability ENSRNOG00000007970 0.05 0.03 blup 3125 0.04 3.0e-03 -9.1 8.7 2.4e-18 -0.77 0.53 0.39 FALSE
98 PL2 Cradd mRNA stability ENSRNOG00000008507 0.08 0.01 blup 3492 0.04 1.9e-03 -8.3 8.9 6.9e-19 -0.71 0.33 0.59 TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.