Hub : Genes

Grk5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative polyA XM_039088801.1 0.06 0.04 8.5e-03 0.03 0.02 -0 0.02 1.2e-02 3.0e-02 6.5e-01 4.7e-02
2 Adipose alternative polyA XM_039088801.1 0.1 0.06 1.8e-13 0.12 0.12 0.13 0.12 1.0e-13 1.6e-13 8.2e-14 1.5e-13
3 NAcc mRNA stability Grk5 0.06 0.03 1.2e-07 0.03 0.05 0.05 0.05 8.9e-05 6.2e-07 1.8e-06 2.7e-06
4 PL alternative polyA XM_039088820.1 0.02 0.02 5.4e-03 0.03 0.02 0.02 0.02 5.6e-04 5.4e-03 2.0e-03 1.1e-03
5 PL alternative polyA XM_039088820.1 0.04 0.03 3.8e-04 0.04 0.04 0.03 0.03 4.0e-05 8.8e-05 2.2e-04 2.0e-04
6 Adipose alternative polyA XM_039088801.1 0.11 0.06 2.6e-14 0.13 0.13 0.13 0.13 1.5e-14 2.4e-14 2.0e-14 2.9e-14
7 NAcc alternative polyA XM_039088801.1 0.02 0.02 1.9e-03 0.03 0.02 0.02 0.03 2.1e-04 8.2e-04 7.2e-04 3.9e-04
8 NAcc alternative polyA XM_039088801.1 0.02 0.02 1.7e-03 0.03 0.02 0.01 0.02 5.5e-04 7.9e-04 1.3e-02 1.9e-03
9 Brain alternative polyA XM_039088820.1 0.03 0.02 2.7e-03 0.04 0.03 0.02 0.03 1.1e-04 1.6e-03 4.0e-03 5.6e-04
10 Brain alternative polyA XM_039088820.1 0.03 0.02 3.4e-03 0.04 0.03 0.03 0.03 1.1e-04 1.9e-03 1.6e-03 4.0e-04
11 BLA mRNA stability Grk5 0.05 0.04 1.0e-02 0.01 -0 -0 0 1.3e-01 8.0e-01 5.6e-01 1.9e-01
12 Adipose alternative polyA XM_039088820.1 0.07 0.04 1.3e-09 0.09 0.09 0.09 0.09 1.5e-10 3.7e-10 2.6e-10 5.3e-10
13 Adipose alternative polyA XM_039088820.1 0.07 0.04 3.4e-09 0.09 0.09 0.09 0.09 3.3e-10 7.6e-10 4.0e-10 7.1e-10
14 Adipose isoform ratio XM_039088828.1 0.03 0.02 1.8e-03 0.01 0.01 0 0 1.3e-02 5.8e-02 1.3e-01 1.0e-01
15 Brain alternative polyA XM_039088801.1 0.02 0.02 3.2e-03 0.03 0.03 0.03 0.03 6.0e-04 1.2e-03 1.8e-03 1.0e-03
16 Brain alternative polyA XM_039088801.1 0.02 0.02 3.5e-03 0.03 0.03 0.02 0.03 8.1e-04 1.4e-03 9.2e-03 1.2e-03
17 Brain isoform ratio XM_039088828.1 0.03 0.02 2.9e-04 0.04 0.04 0.03 0.04 3.2e-04 2.4e-04 8.5e-04 1.6e-04
18 Liver mRNA stability Grk5 0.03 0.02 7.8e-03 0 0.01 0.01 0.01 2.0e-01 5.6e-02 4.0e-02 3.2e-02
19 Adipose gene expression Grk5 0.2 0.09 0.0e+00 0.24 0.23 0.24 0.23 5.4e-26 1.8e-25 5.3e-26 8.1e-26
20 Brain mRNA stability Grk5 0.04 0.02 8.3e-04 0.02 0.03 0.03 0.03 6.7e-03 6.6e-04 4.8e-04 1.4e-03
21 PL alternative polyA XM_039088801.1 0.03 0.02 2.1e-03 0.02 0.02 0.01 0.01 5.5e-03 4.0e-03 6.4e-02 8.0e-03
22 pVTA mRNA stability Grk5 0.1 0.07 2.1e-03 0.06 0.04 0.05 0.05 1.4e-03 7.9e-03 3.0e-03 4.4e-03
23 PL alternative polyA XM_039088801.1 0.04 0.03 7.2e-04 0.02 0.02 0.01 0.01 4.7e-03 3.7e-03 4.8e-02 9.6e-03
24 Adipose mRNA stability Grk5 0.02 0.01 9.9e-03 0.01 0 0 -0 5.3e-02 3.4e-01 2.9e-01 4.2e-01
25 LHb mRNA stability Grk5 0.28 0.2 9.6e-03 0.05 0.09 0.05 0.06 2.4e-02 4.3e-03 2.0e-02 2.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.93.212.93.62.0-1.9-1.7-1.71.81.81.8-1.6-1.61.8-1.8-1.81.81.81.8-1.7-2.7-1.71.6-1.11.6-0.8-0.9-0.8
Area under the delay curve0.80.91.5-0.30.9-0.3-1.0-1.01.01.11.1-1.0-1.01.1-1.1-1.11.11.11.1-1.0-0.6-0.70.5-1.20.1-1.2-0.8-0.5
BMI with tail28.090.7152.612.410.2-10.3-9.9-9.99.79.89.8-9.7-9.79.6-9.7-9.79.79.79.7-9.7-9.1-9.79.6-8.88.3-8.1-7.7-6.8
BMI without tail20.341.959.07.77.0-6.4-6.9-6.96.76.76.7-6.7-6.76.8-6.8-6.86.86.86.8-6.7-6.7-6.25.9-5.95.4-5.4-4.5-5.3
Body weight26.1109.4178.513.411.2-11.1-10.8-10.810.710.710.7-10.6-10.610.7-10.7-10.710.710.710.7-10.7-10.4-10.510.2-9.49.5-8.7-8.2-7.7
Weight adjusted by age5.76.48.12.42.7-2.7-2.8-2.82.62.52.5-2.7-2.72.5-2.5-2.52.52.52.5-2.6-2.0-2.42.5-2.52.4-2.4-1.9-2.6
Bone surface2.03.510.43.22.1-2.0-1.7-1.71.91.91.9-1.7-1.71.9-1.9-1.91.91.91.9-1.9-2.4-2.01.7-1.31.8-1.1-1.1-0.7
Bone volume4.57.616.94.13.0-3.0-2.6-2.62.82.82.8-2.6-2.62.8-2.8-2.82.82.82.8-2.8-3.1-3.02.8-2.32.8-2.0-2.2-1.5
Breakpoint value in progressive ratio session3.53.96.01.02.2-1.2-2.0-2.02.22.12.1-2.0-2.02.3-2.3-2.32.32.32.3-2.2-2.4-1.41.3-1.71.0-1.6-1.1-2.1
Number of licking bursts0.20.21.00.40.40.4-0.3-0.30.40.40.4-0.3-0.30.4-0.4-0.40.40.40.4-0.2-1.00.4-0.40.1-0.40.20.6-0.4
Context. condit. distance diff. score0.10.10.70.6-0.20.20.30.3-0.2-0.2-0.20.30.3-0.30.30.3-0.3-0.3-0.30.3-0.10.3-0.30.4-0.10.50.30.8
Locomotion velocity, session 11.21.32.4-1.6-1.11.31.11.1-1.1-1.1-1.11.21.2-1.01.01.0-1.0-1.0-1.01.11.21.5-1.31.2-1.41.21.10.3
Locomotion distance, session 12.32.95.0-1.7-1.91.41.81.8-1.9-1.9-1.91.91.9-1.81.81.8-1.8-1.8-1.81.72.01.2-1.31.3-0.61.21.02.2
Locomotion velocity, session 21.21.43.3-1.5-1.30.81.31.3-1.3-1.3-1.31.31.3-1.31.31.3-1.3-1.3-1.31.21.80.8-0.71.0-0.40.80.40.9
Locomotion distance, session 20.30.42.40.90.3-1.1-0.2-0.20.20.20.2-0.2-0.20.2-0.2-0.20.20.20.2-0.40.2-1.11.0-0.61.5-0.6-1.00.7
Locomotion velocity, session 32.52.94.3-1.7-1.81.71.91.9-1.8-1.8-1.81.81.8-1.81.81.8-1.8-1.8-1.81.81.31.4-1.61.5-1.11.41.32.1
Locomotion distance, session 31.21.31.6-1.1-1.21.01.31.3-1.2-1.2-1.21.21.2-1.21.31.3-1.3-1.3-1.31.21.21.0-0.91.1-0.81.00.81.2
Stereotopy head waving bouts, day 30.20.31.2-1.1-0.60.30.50.5-0.5-0.5-0.50.50.5-0.60.60.6-0.6-0.6-0.60.51.10.1-0.20.10.1-0.0-0.10.4
Stereotopy head waving duration, day 30.10.21.9-1.4-0.40.30.30.3-0.2-0.2-0.20.30.3-0.30.30.3-0.3-0.3-0.30.21.00.1-0.1-0.20.0-0.3-0.30.0
Locomotion velocity, session 70.20.21.10.2-0.40.40.30.3-0.4-0.4-0.40.30.3-0.50.50.5-0.5-0.5-0.50.5-0.00.3-0.60.3-0.10.40.61.0
Locomotion distance, session 70.20.21.91.40.2-0.7-0.2-0.20.10.10.1-0.2-0.2-0.10.10.1-0.1-0.1-0.10.0-0.4-0.60.5-0.11.0-0.1-0.30.6
Stereotopy head waving bouts, day 70.20.21.2-1.10.20.9-0.3-0.30.30.30.3-0.3-0.30.4-0.4-0.40.40.40.4-0.2-0.30.6-1.0-0.2-0.7-0.20.8-0.3
Stereotopy head waving duration, day 70.30.42.1-1.4-0.11.4-0.1-0.10.10.10.1-0.1-0.10.2-0.2-0.20.20.20.20.0-0.30.8-1.4-0.0-1.0-0.01.1-0.0
Locomotion velocity, session 82.32.73.7-0.9-1.71.71.81.8-1.6-1.6-1.61.81.8-1.61.61.6-1.6-1.6-1.61.70.81.7-1.71.9-1.51.91.71.6
Locomotion distance, session 80.81.23.20.3-1.10.61.21.2-1.1-1.1-1.11.21.2-1.21.21.2-1.2-1.2-1.21.20.70.9-0.71.3-0.41.30.81.8
Degree of sensitization distance1.51.54.52.11.3-1.5-1.3-1.31.21.21.2-1.2-1.21.1-1.1-1.11.11.11.1-1.1-1.4-1.31.4-1.01.4-0.9-0.9-0.9
Degree of sensitization stereotypy0.60.61.0-0.40.70.5-0.8-0.80.80.80.8-0.8-0.81.0-1.0-1.01.01.01.0-0.8-0.90.2-0.6-0.6-0.5-0.60.5-0.7
Conditioned locomotion0.00.00.5-0.6-0.00.30.10.1-0.0-0.0-0.00.10.10.1-0.1-0.10.10.10.1-0.10.10.4-0.10.0-0.70.0-0.0-0.4
Cocaine response after cond. corrected3.13.57.5-1.2-2.10.52.22.2-2.2-2.2-2.22.22.2-2.22.22.2-2.2-2.2-2.21.82.70.6-0.41.5-0.01.30.12.2
Cocaine response after cond. not corrected4.34.77.2-1.7-2.41.22.52.5-2.5-2.5-2.52.52.5-2.42.42.4-2.4-2.4-2.42.22.71.5-1.22.1-1.11.90.81.8
Cocaine response before conditioning0.60.74.9-0.6-0.21.30.00.0-0.1-0.1-0.10.10.1-0.10.10.1-0.1-0.1-0.10.4-0.71.6-1.30.9-2.21.01.6-1.4
Saline control response0.10.21.8-1.3-0.1-0.00.00.00.0-0.0-0.00.10.10.0-0.0-0.00.00.00.0-0.20.90.00.3-0.3-0.4-0.5-0.6-0.8
Bone: connectivity density0.10.22.31.50.2-0.20.00.00.10.10.10.10.10.1-0.1-0.10.10.10.1-0.0-1.0-0.2-0.10.30.10.40.40.8
Bone: cortical apparent density7.610.012.9-3.2-3.62.63.33.3-3.5-3.5-3.53.33.3-3.63.63.6-3.6-3.6-3.63.43.32.5-2.42.7-1.72.51.83.0
Bone: cortical area12.118.324.95.04.6-4.4-4.4-4.44.54.44.4-4.4-4.44.3-4.4-4.44.44.44.4-4.4-4.1-4.34.2-3.93.8-3.7-3.6-3.4
Bone: cortical porosity1.01.02.81.51.2-0.8-1.1-1.11.31.11.1-1.1-1.11.0-1.0-1.01.01.01.0-0.9-1.7-0.90.7-0.80.7-0.6-0.6-0.6
Bone: cortical porosity2.12.34.61.81.7-1.2-1.7-1.71.81.61.6-1.6-1.61.5-1.5-1.51.51.51.5-1.4-2.2-1.31.1-1.31.1-1.1-0.8-1.1
Bone: cortical thickness7.412.116.44.03.6-4.0-3.6-3.63.53.43.4-3.5-3.53.3-3.3-3.33.33.33.3-3.5-3.0-3.93.9-3.43.7-3.2-3.5-2.5
Bone: cortical thickness7.89.114.52.43.0-3.4-2.8-2.83.02.92.9-2.9-2.92.9-2.9-2.92.92.92.9-3.1-1.9-3.63.6-3.33.8-3.3-3.7-1.9
Bone: cortical tissue density8.611.314.5-3.4-3.82.83.53.5-3.8-3.7-3.73.53.5-3.83.83.8-3.8-3.8-3.83.63.42.7-2.72.9-1.92.72.13.2
Condit. Reinf. active minus inactive responses2.62.94.90.1-1.71.41.71.7-1.8-1.8-1.81.71.7-1.81.81.8-1.8-1.8-1.81.90.71.5-1.72.0-1.22.01.92.2
Condit. Reinf. active-inactive response ratio2.42.63.4-0.9-1.61.61.51.5-1.6-1.6-1.61.51.5-1.71.61.6-1.6-1.6-1.61.81.11.7-1.81.8-1.81.81.81.4
Condit. Reinf. active responses0.50.64.42.1-0.4-0.10.50.5-0.6-0.5-0.50.50.5-0.60.60.6-0.6-0.6-0.60.6-0.6-0.0-0.40.80.41.00.81.7
Condit. Reinf. inactive responses1.31.610.03.21.2-1.6-1.0-1.01.01.01.0-1.0-1.01.0-1.0-1.01.01.01.0-1.0-1.9-1.51.2-0.71.8-0.4-0.70.2
Incentive salience index mean1.82.15.60.6-1.40.81.51.5-1.6-1.6-1.61.51.5-1.61.61.6-1.6-1.6-1.61.60.60.8-1.21.6-0.51.71.42.4
Condit. Reinf. lever presses0.91.14.90.8-1.00.31.11.1-1.2-1.2-1.21.11.1-1.21.21.2-1.2-1.2-1.21.10.40.1-0.61.00.21.10.72.2
Condit. Reinf. active minus inactive responses2.02.54.61.41.8-0.9-1.7-1.71.71.71.7-1.8-1.81.9-1.8-1.81.81.81.8-1.7-2.1-0.80.7-1.00.2-0.9-0.3-2.1
Condit. Reinf. active-inactive response ratio3.43.66.01.02.1-1.2-2.1-2.12.02.02.0-2.2-2.22.2-2.2-2.22.22.22.2-2.1-2.0-1.21.0-1.60.7-1.5-0.7-2.4
Condit. Reinf. active responses2.12.96.92.21.9-1.1-1.9-1.91.81.91.9-2.0-2.01.9-1.9-1.91.91.91.9-1.7-2.6-1.00.8-1.10.5-0.9-0.3-1.8
Condit. Reinf. inactive responses0.50.72.91.70.9-0.5-0.9-0.90.90.90.9-0.9-0.90.8-0.8-0.80.80.80.8-0.7-1.5-0.30.4-0.30.1-0.2-0.1-0.7
Condit. Reinf. lever presses1.52.04.62.11.5-1.3-1.5-1.51.51.51.5-1.5-1.51.4-1.4-1.41.41.41.4-1.4-2.1-1.21.2-1.10.9-0.9-0.9-1.2
Condit. Reinf. lever reinforcers received1.11.64.71.81.4-0.6-1.3-1.31.31.31.3-1.4-1.41.4-1.4-1.41.41.41.4-1.2-2.2-0.50.4-0.60.0-0.3-0.0-1.4
Conditioned reinforcement - actives4.84.88.4-2.9-2.22.32.32.3-2.3-2.3-2.32.42.4-2.12.12.1-2.1-2.1-2.12.12.32.3-2.12.3-2.02.21.91.1
Conditioned reinforcement - inactives0.50.50.9-0.3-0.70.80.70.7-0.8-0.8-0.81.01.0-0.70.70.7-0.7-0.7-0.70.7-0.10.6-0.80.7-0.40.80.80.9
Conditioned locomotion3.74.45.8-2.0-2.11.92.22.2-2.3-2.3-2.32.42.4-2.02.02.0-2.0-2.0-2.02.02.12.2-1.82.4-2.22.31.71.2
Patch foraging indifference point 0 sec5.28.412.63.53.0-3.0-3.0-3.02.93.03.0-3.0-3.02.8-2.9-2.92.92.92.9-2.9-3.2-3.12.8-2.93.0-2.7-2.3-1.8
Patch foraging indifference point AUC0.60.71.10.30.8-0.6-0.8-0.80.80.80.8-0.8-0.81.0-1.0-1.01.01.01.0-1.0-0.8-0.70.7-0.90.6-0.9-0.9-0.7
Delay disc. indifference point, 0s delay0.60.71.50.50.8-1.0-1.1-1.10.80.80.8-0.9-0.90.7-0.6-0.60.60.60.6-0.7-0.4-1.21.0-1.10.4-1.1-1.0-0.5
Delay disc. indifference point, 16s delay0.40.40.8-0.60.60.2-0.7-0.70.70.80.8-0.7-0.70.9-0.8-0.80.80.80.8-0.7-0.3-0.1-0.0-0.7-0.6-0.7-0.2-0.6
Delay disc. indifference point, 2s delay0.10.10.6-0.50.1-0.1-0.0-0.00.20.20.2-0.1-0.10.2-0.2-0.20.20.20.2-0.30.5-0.50.2-0.60.7-0.7-0.70.6
Delay disc. indifference point, 24s delay0.70.61.1-0.20.8-0.3-0.9-0.90.90.90.9-0.9-0.91.0-0.9-0.90.90.90.9-0.8-0.8-0.70.5-1.00.4-1.0-0.6-0.3
Delay disc. indifference point, 4s delay0.40.50.9-0.40.6-0.1-0.7-0.70.70.80.8-0.7-0.70.9-0.8-0.80.80.80.8-0.7-0.4-0.60.3-0.90.2-1.0-0.6-0.3
Delay disc. indifference point, 8s delay0.10.10.5-0.60.20.0-0.3-0.30.30.30.3-0.4-0.40.4-0.3-0.30.30.30.3-0.3-0.1-0.20.1-0.6-0.2-0.7-0.40.1
Indifference point function ln k0.10.20.80.80.2-0.9-0.3-0.30.00.10.1-0.2-0.2-0.0-0.0-0.00.00.00.0-0.10.4-0.60.7-0.20.7-0.2-0.6-0.1
Indifference point function log k0.10.20.80.80.2-0.9-0.3-0.30.00.10.1-0.2-0.2-0.0-0.0-0.00.00.00.0-0.10.4-0.60.7-0.20.7-0.2-0.6-0.1
Patch foraging total patch changes 0 sec6.510.514.93.93.4-3.4-3.4-3.43.33.33.3-3.3-3.33.2-3.2-3.23.23.23.2-3.2-3.4-3.43.1-3.33.2-3.1-2.7-2.1
Patch foraging total patch changes 12 sec4.25.48.52.92.5-2.2-2.3-2.32.42.32.3-2.4-2.42.4-2.4-2.42.42.42.4-2.4-2.9-2.22.1-2.21.9-2.0-1.8-1.4
Patch foraging total patch changes 18 sec2.43.05.32.21.8-1.6-1.8-1.81.81.81.8-1.7-1.71.8-1.8-1.81.81.81.8-1.8-2.3-1.71.6-1.61.6-1.5-1.4-1.2
Patch foraging total patch changes 24 sec0.60.73.61.10.8-0.6-0.9-0.90.80.80.8-0.9-0.90.8-0.7-0.70.70.70.7-0.7-1.9-0.80.6-0.90.7-0.8-0.5-0.3
Patch foraging total patch changes 6 sec4.87.111.33.12.8-2.5-2.8-2.82.72.72.7-2.6-2.62.7-2.7-2.72.72.72.7-2.7-3.4-2.62.5-2.72.4-2.5-2.3-1.9
Patch foraging time to switch 0 sec1.42.23.1-1.7-1.51.71.71.7-1.4-1.4-1.41.41.4-1.41.41.4-1.4-1.4-1.41.51.21.6-1.51.6-1.41.61.31.0
Patch foraging water rate 0 sec3.14.97.52.72.2-2.6-2.3-2.32.22.12.1-2.3-2.32.1-2.1-2.12.12.12.1-2.2-1.8-2.42.4-2.42.1-2.3-2.1-1.3
Patch foraging water rate 12 sec3.24.96.02.22.3-2.0-2.5-2.52.22.32.3-2.4-2.42.3-2.4-2.42.42.42.4-2.3-2.1-1.91.9-2.11.7-1.9-1.6-2.0
Patch foraging water rate 18 sec1.21.63.91.41.1-1.9-1.3-1.31.00.90.9-1.1-1.11.0-0.9-0.90.90.90.9-1.1-0.3-1.71.8-1.62.0-1.6-1.7-0.8
Patch foraging water rate 24 sec4.15.810.82.82.2-3.3-2.4-2.42.12.12.1-2.2-2.22.0-2.0-2.02.02.02.0-2.3-1.1-3.03.2-2.83.0-2.8-3.1-1.3
Patch foraging water rate 6 sec2.13.15.61.91.7-2.4-1.8-1.81.51.51.5-1.8-1.81.6-1.6-1.61.61.61.6-1.8-0.9-2.02.3-1.82.0-1.8-2.0-1.5
Seeking ratio, delayed vs. immediate footshock9.010.313.8-2.3-3.33.03.73.7-3.2-3.3-3.33.43.4-3.43.43.4-3.4-3.4-3.43.32.72.9-2.93.4-2.03.32.43.7
Distance traveled before self-admin0.40.43.2-1.6-0.5-0.00.40.4-0.3-0.5-0.50.30.3-0.50.50.5-0.5-0.5-0.50.31.8-0.20.2-0.31.2-0.5-0.80.5
Distance traveled after self-admin1.61.82.9-1.7-1.60.91.11.1-1.5-1.5-1.51.31.3-1.61.61.6-1.6-1.6-1.61.51.60.7-0.90.7-0.80.60.51.5
Extensor digitorum longus weight2.08.011.13.33.0-3.0-3.1-3.13.03.03.0-3.0-3.02.8-2.8-2.82.82.82.8-2.8-2.5-2.52.9-2.42.4-2.3-2.3-3.0
Bone: elastic displacement0.40.51.8-0.80.6-0.6-0.6-0.60.70.60.6-0.5-0.50.5-0.5-0.50.50.50.5-0.60.2-0.70.9-0.90.5-1.0-1.1-1.3
Bone: elastic work3.24.18.20.71.9-2.4-1.8-1.81.91.81.8-1.8-1.81.9-1.9-1.91.91.91.9-2.2-0.5-2.72.5-2.52.9-2.5-2.8-1.4
Bone: endosteal estimation1.94.15.72.42.3-2.0-2.0-2.02.22.22.2-2.1-2.12.2-2.2-2.22.22.22.2-2.2-1.9-2.11.9-1.81.8-1.7-1.5-1.4
Bone: endosteal perimeter3.87.99.52.43.1-2.6-2.9-2.93.13.13.1-3.0-3.03.1-3.1-3.13.13.13.1-3.0-2.3-2.62.5-2.72.1-2.6-2.1-2.5
Epididymis fat weight32.074.5136.911.79.3-8.7-9.1-9.19.09.09.0-9.0-9.08.8-8.8-8.88.88.88.8-8.7-9.5-8.17.9-7.57.0-6.8-6.1-6.4
Delta time in closed arm before/after self-admin0.40.40.70.2-0.6-0.00.80.8-0.8-0.7-0.70.60.6-0.70.70.7-0.7-0.7-0.70.60.80.2-0.20.6-0.30.60.20.8
Delta time in open arm before/after self-admin0.60.63.00.50.60.6-0.7-0.70.70.70.7-0.6-0.60.5-0.5-0.50.50.50.5-0.3-1.70.7-0.50.3-1.40.40.8-1.7
Diff in mean of infusions in LGA sessions0.70.81.8-0.30.9-0.1-1.1-1.10.90.90.9-1.0-1.01.0-1.0-1.01.01.01.0-0.9-1.2-0.40.1-0.90.1-0.90.0-1.3
Delay discount exponential model param1.01.01.80.3-1.00.41.01.0-1.1-1.2-1.21.11.1-1.21.21.2-1.2-1.2-1.21.10.60.8-0.61.3-0.31.30.90.6
Extinction: sum of active levers before priming0.10.10.70.20.00.5-0.0-0.00.00.10.10.10.10.2-0.2-0.20.20.20.2-0.1-0.80.4-0.60.1-0.50.20.70.2
Active lever presses in extinction session 62.82.73.60.81.7-1.4-1.8-1.81.61.71.7-1.6-1.61.8-1.8-1.81.81.81.8-1.9-1.5-1.61.3-1.91.3-1.9-1.1-1.3
Bone: final force8.814.218.24.33.9-4.2-3.7-3.73.93.83.8-3.7-3.73.7-3.7-3.73.73.73.7-3.9-3.1-4.14.1-3.64.3-3.4-3.7-2.5
Bone: final moment9.214.819.64.44.0-4.3-3.8-3.84.03.93.9-3.8-3.83.8-3.8-3.83.83.83.8-4.0-3.3-4.24.1-3.74.2-3.5-3.7-2.6
Food consumed during 24 hour testing period0.40.40.80.80.7-0.8-0.6-0.60.60.60.6-0.6-0.60.6-0.6-0.60.60.60.6-0.7-0.7-0.60.9-0.50.8-0.4-0.6-0.7
Glucose7.811.715.72.63.7-2.4-4.0-4.03.93.93.9-3.9-3.93.8-3.8-3.83.83.83.8-3.5-3.6-2.42.2-3.11.4-2.9-1.7-3.8
Heart weight9.713.716.53.74.1-3.5-3.8-3.84.03.93.9-4.0-4.04.0-3.9-3.93.93.93.9-3.9-3.4-3.43.3-3.53.2-3.3-2.7-3.1
Delay discount hyperbolic model param0.70.81.50.4-0.80.30.90.9-1.0-1.0-1.01.01.0-1.11.01.0-1.0-1.0-1.01.00.40.8-0.51.2-0.41.20.90.3
Intermittent access intake day 1-15 change0.20.21.2-0.40.3-0.0-0.6-0.60.30.30.3-0.3-0.30.3-0.3-0.30.30.30.3-0.3-0.5-0.10.1-0.30.0-0.4-0.1-1.1
Intermittent access intake escalation0.10.10.6-0.50.0-0.2-0.4-0.40.00.00.0-0.1-0.10.0-0.0-0.00.00.00.0-0.10.2-0.20.3-0.30.3-0.3-0.3-0.8
Intermittent access intake escalation 20.30.31.8-0.10.5-0.4-0.7-0.70.40.40.4-0.6-0.60.5-0.5-0.50.50.50.5-0.5-0.3-0.30.4-0.40.1-0.4-0.3-1.4
Intermitt. access day 1 inactive lever presses0.80.92.61.30.9-0.8-1.2-1.20.90.90.9-1.0-1.00.9-0.9-0.90.90.90.9-0.9-1.6-0.80.6-0.90.6-0.8-0.5-0.8
Intermitt. access day 15 inactive lever presses2.02.23.50.61.4-1.5-1.8-1.81.41.31.3-1.4-1.41.5-1.5-1.51.51.51.5-1.6-1.1-1.61.6-1.91.3-1.9-1.7-1.5
Intermitt. access escalation Index0.20.10.2-0.0-0.40.20.00.0-0.5-0.4-0.40.30.3-0.50.50.5-0.5-0.5-0.50.50.20.4-0.30.5-0.40.50.4-0.2
Intermittent access day 1 total infusions0.40.50.9-0.9-0.70.80.70.7-0.7-0.7-0.70.90.9-0.60.60.6-0.6-0.6-0.60.60.70.7-0.70.7-0.40.70.50.5
Intermittent access day 15 total infusions0.20.21.4-1.2-0.50.50.40.4-0.6-0.6-0.60.60.6-0.40.40.4-0.4-0.4-0.40.40.70.4-0.30.3-0.10.20.1-0.2
Intermittent access terminal intake (last 3 days)0.00.10.6-0.8-0.10.20.10.1-0.2-0.2-0.20.20.2-0.00.00.0-0.0-0.0-0.0-0.00.40.3-0.10.10.10.0-0.1-0.4
Intermittent access total infusions0.60.71.6-1.3-0.80.90.90.9-0.9-0.9-0.91.11.1-0.60.60.6-0.6-0.6-0.60.61.01.0-0.80.8-0.50.80.50.2
Intermittent access day 1 locomotion2.52.64.3-1.2-1.81.31.81.8-2.0-1.9-1.92.02.0-1.61.61.6-1.6-1.6-1.61.51.91.4-1.21.4-0.41.30.92.1
Intermittent access day 15 total locomotion0.10.10.40.30.20.1-0.3-0.30.20.20.2-0.1-0.10.4-0.4-0.40.40.40.4-0.3-0.60.1-0.2-0.20.3-0.20.30.0
Intermittent access total locomotion1.11.32.3-0.8-1.20.91.31.3-1.4-1.4-1.41.41.4-1.11.11.1-1.1-1.1-1.11.01.41.0-1.01.0-0.11.00.81.5
Intermittent access standard deviation0.20.21.0-0.9-0.00.80.20.20.0-0.0-0.00.40.40.1-0.1-0.10.10.10.10.0-0.20.8-0.60.5-1.00.50.5-0.8
Left kidney weight11.131.248.46.85.8-7.0-5.2-5.25.45.45.4-5.3-5.35.5-5.5-5.55.55.55.5-5.9-3.8-6.26.7-5.05.8-4.8-6.0-4.3
Right kidney weight10.830.349.27.05.7-7.0-5.1-5.15.35.35.3-5.2-5.25.3-5.3-5.35.35.35.3-5.7-3.7-6.16.7-5.06.0-4.8-6.2-4.1
Cocaine induced anxiety3.44.06.7-2.6-2.01.92.32.3-2.1-2.1-2.12.02.0-1.81.81.8-1.8-1.8-1.81.82.32.1-1.72.1-2.61.91.40.9
Post-drug Anxiety0.91.02.2-1.0-1.01.21.11.1-1.0-1.0-1.00.90.9-0.90.90.9-0.9-0.9-0.90.91.01.3-1.11.1-1.51.11.00.4
Baseline Anxiety1.31.43.82.01.1-0.8-1.6-1.61.21.21.2-1.2-1.21.0-1.0-1.01.01.01.0-0.9-1.9-0.90.5-1.21.5-1.0-0.2-0.6
Tail length1.23.58.01.02.1-1.3-2.1-2.12.02.12.1-2.0-2.02.1-2.1-2.12.12.12.1-2.0-2.1-1.31.3-1.50.9-1.4-0.9-2.8
Length with tail3.312.114.43.83.8-3.3-3.6-3.63.63.73.7-3.6-3.63.7-3.7-3.73.73.73.7-3.6-3.7-3.23.1-3.03.3-2.8-2.5-3.1
Length without tail3.98.619.54.43.1-3.3-2.9-2.93.02.92.9-3.0-3.02.8-2.9-2.92.92.92.9-2.9-3.0-3.03.0-2.53.1-2.3-2.5-1.6
Times rat made contact with spout1.21.42.61.61.3-1.3-1.3-1.31.21.11.1-1.3-1.31.1-1.1-1.11.11.11.1-1.1-1.2-1.11.2-1.01.4-0.9-0.7-0.9
Lifetime Intake0.80.91.9-1.4-1.01.01.11.1-1.0-1.0-1.01.31.3-0.90.90.9-0.9-0.9-0.90.81.21.0-0.80.9-0.40.80.40.6
Liver weight, left5.79.117.24.13.2-2.9-3.1-3.13.13.13.1-3.0-3.03.1-3.1-3.13.13.13.1-3.0-3.8-2.92.5-2.72.9-2.4-1.9-1.7
Liver weight, right8.714.532.25.74.1-3.8-4.0-4.04.03.93.9-3.9-3.93.9-3.9-3.93.93.93.9-3.8-4.6-3.63.3-3.23.4-2.8-2.3-2.5
Locomotor activity0.10.20.5-0.3-0.50.50.10.1-0.5-0.5-0.50.10.1-0.60.60.6-0.6-0.6-0.60.60.10.6-0.60.5-0.70.50.70.0
Locomotor testing distance0.40.71.1-1.0-1.00.60.80.8-1.0-0.9-0.90.80.8-1.11.11.1-1.1-1.1-1.11.00.90.6-0.50.6-0.50.60.40.6
Locomotor testing rearing0.20.31.9-1.30.2-0.3-0.4-0.40.30.30.3-0.4-0.40.2-0.2-0.20.20.20.2-0.30.6-0.20.5-0.6-0.2-0.8-0.7-1.4
Locomotion in novel chamber0.81.06.51.10.7-1.5-0.4-0.40.60.70.7-0.5-0.50.8-0.7-0.70.70.70.7-1.00.0-1.51.5-1.02.5-1.1-1.60.6
Locomotion in novel chamber post-restriction0.40.52.6-0.2-0.3-0.80.30.3-0.4-0.4-0.40.30.3-0.30.20.2-0.2-0.2-0.2-0.01.2-0.90.8-0.61.6-0.7-1.21.4
Fecal boli incidents, locomotor time 10.40.51.20.20.70.0-0.6-0.60.70.60.6-0.7-0.70.8-0.9-0.90.90.90.9-0.7-0.50.1-0.1-0.4-0.8-0.40.4-1.1
Change in fecal boli incidents, locomotor task0.30.21.41.20.4-0.8-0.4-0.40.30.50.5-0.2-0.20.3-0.2-0.20.20.20.2-0.2-0.9-0.60.7-0.20.7-0.1-0.5-0.2
Time >=10cm from walls, locomotor time 10.30.30.5-0.1-0.60.60.50.5-0.5-0.5-0.50.60.6-0.70.70.7-0.7-0.7-0.70.70.20.6-0.50.6-0.60.60.60.4
Bouts of movement, locomotor time 10.20.21.50.20.4-0.1-0.6-0.60.50.30.3-0.6-0.60.2-0.2-0.20.20.20.2-0.2-1.0-0.10.2-0.1-0.4-0.10.1-1.2
Total resting periods, locomotor time 10.20.21.70.20.5-0.4-0.6-0.60.60.40.4-0.6-0.60.2-0.3-0.30.30.30.3-0.3-0.8-0.30.4-0.3-0.3-0.2-0.2-1.3
Rest time, locomotor task time 10.40.51.80.30.6-1.3-0.6-0.60.50.30.3-0.5-0.50.4-0.4-0.40.40.40.4-0.60.4-0.91.4-0.50.3-0.6-1.3-1.1
Distance moved, locomotor task time 10.20.21.3-0.3-0.50.60.40.4-0.4-0.5-0.50.40.4-0.30.30.3-0.3-0.3-0.30.4-0.00.2-0.6-0.0-0.1-0.00.51.2
Vertical activity count, locomotor time 10.70.73.5-0.4-0.90.70.80.8-0.9-0.9-0.90.80.8-0.90.90.9-0.9-0.9-0.90.80.40.4-0.80.4-0.00.30.81.9
Time >=10cm from walls, locomotor time 20.20.21.51.20.1-0.6-0.1-0.10.20.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.10.1-0.3-0.60.5-0.20.7-0.2-0.40.7
Bouts of movement, locomotor time 20.10.11.3-1.10.00.20.10.10.00.10.1-0.1-0.10.0-0.0-0.00.00.00.0-0.10.50.30.00.2-0.50.1-0.2-0.9
Total resting periods, locomotor time 20.10.11.6-1.3-0.10.30.00.00.00.00.0-0.1-0.1-0.10.10.1-0.1-0.1-0.10.00.50.3-0.00.2-0.70.1-0.2-0.9
Rest time, locomotor task time 20.20.21.3-1.0-0.30.3-0.1-0.1-0.1-0.5-0.50.10.1-0.50.50.5-0.5-0.5-0.50.50.50.4-0.10.2-1.10.10.2-0.8
Distance moved, locomotor task time 20.10.11.20.7-0.1-0.20.30.3-0.3-0.2-0.20.20.2-0.00.00.0-0.0-0.0-0.0-0.1-0.1-0.40.1-0.10.8-0.1-0.21.1
Vertical activity count, locomotor time 20.30.32.40.7-0.50.20.60.6-0.6-0.6-0.60.60.6-0.50.50.5-0.5-0.5-0.50.50.00.0-0.40.40.50.50.41.6
Light reinforcement 10.20.31.20.1-0.4-0.40.60.6-0.6-0.6-0.60.40.4-0.40.40.4-0.4-0.4-0.40.20.5-0.60.40.11.10.0-0.61.0
Light reinforcement 20.20.20.5-0.6-0.40.60.60.6-0.5-0.5-0.50.40.4-0.20.20.2-0.2-0.2-0.20.30.60.5-0.70.7-0.30.70.70.2
Bone: marrow area2.14.66.42.52.4-2.2-2.1-2.12.32.32.3-2.2-2.22.3-2.3-2.32.32.32.3-2.3-2.0-2.22.0-1.91.9-1.8-1.6-1.5
Bone: maximum diameter5.910.815.13.93.6-2.9-3.5-3.53.63.63.6-3.5-3.53.6-3.6-3.63.63.63.6-3.4-3.9-2.82.6-2.82.1-2.6-2.0-2.8
Bone: maximum force6.711.618.54.33.5-4.0-3.3-3.33.43.33.3-3.4-3.43.3-3.3-3.33.33.33.3-3.4-2.8-3.93.8-3.24.0-3.0-3.3-1.9
Bone: maximum moment6.811.719.44.43.6-4.0-3.3-3.33.43.43.4-3.4-3.43.3-3.3-3.33.33.33.3-3.4-3.0-3.93.7-3.23.9-3.0-3.2-2.0
Mean time between licks in bursts0.60.82.80.4-0.51.10.60.6-0.6-0.6-0.60.60.6-0.60.60.6-0.6-0.6-0.60.8-0.81.5-1.21.3-1.71.51.60.1
Mean num. licks in bursts0.40.52.40.70.4-1.3-0.4-0.40.20.20.2-0.4-0.40.2-0.2-0.20.20.20.2-0.40.4-1.31.3-0.81.6-0.9-1.20.0
Cd content in liver1.81.93.0-0.2-1.41.11.71.7-1.4-1.4-1.41.61.6-1.41.51.5-1.5-1.5-1.51.50.61.3-1.01.7-1.31.71.01.4
Co content in liver0.20.20.80.8-0.0-0.70.20.2-0.1-0.1-0.10.30.3-0.10.10.1-0.1-0.1-0.1-0.00.3-0.70.6-0.00.9-0.0-0.70.8
Cu content in liver0.50.61.00.40.8-0.6-0.7-0.70.90.90.9-0.6-0.60.9-0.9-0.90.90.90.9-0.9-0.4-0.50.8-0.60.3-0.6-0.9-1.0
Fe content in liver0.00.00.20.4-0.20.10.00.0-0.2-0.1-0.10.10.1-0.20.10.1-0.1-0.1-0.10.2-0.10.2-0.20.20.00.20.30.3
K content in liver0.90.93.0-0.11.0-0.7-0.8-0.81.01.01.0-0.8-0.81.1-1.1-1.11.11.11.1-1.2-0.1-0.40.9-0.80.3-0.8-1.1-1.7
Mg content in liver1.51.54.3-0.51.2-0.9-1.1-1.11.31.31.3-1.1-1.11.4-1.4-1.41.41.41.4-1.50.1-0.71.2-1.20.6-1.3-1.5-2.1
Mn content in liver0.30.31.00.50.5-0.9-0.4-0.40.50.50.5-0.5-0.50.5-0.5-0.50.50.50.5-0.6-0.1-0.91.0-0.60.8-0.7-1.0-0.3
Na content in liver4.64.89.00.52.3-1.6-2.3-2.32.42.42.4-2.3-2.32.5-2.5-2.52.52.52.5-2.5-1.2-1.51.8-2.11.1-2.1-1.8-3.0
Rb content in liver0.20.21.7-1.3-0.50.60.40.4-0.4-0.4-0.40.40.4-0.30.40.4-0.4-0.4-0.40.30.90.5-0.50.2-0.70.10.2-0.1
Se content in liver0.00.10.3-0.5-0.10.30.10.1-0.0-0.0-0.00.20.20.1-0.2-0.20.20.20.2-0.20.60.4-0.10.10.00.1-0.1-0.4
Sr content in liver2.42.27.3-2.5-1.71.01.61.6-1.6-1.6-1.61.41.4-1.61.61.6-1.6-1.6-1.61.42.70.9-0.70.8-0.70.60.21.3
Zn content in liver0.70.73.1-0.50.5-1.2-0.5-0.50.60.60.6-0.4-0.40.5-0.5-0.50.50.50.5-0.81.4-1.01.4-1.01.1-1.2-1.8-1.0
Bone: minimum diameter6.412.014.43.73.8-3.3-3.6-3.63.83.73.7-3.7-3.73.7-3.7-3.73.73.73.7-3.6-3.3-3.33.1-3.12.6-2.9-2.5-3.0
Time in familiar zone, hab. session 12.72.53.11.01.7-1.4-1.8-1.81.81.81.8-1.8-1.81.7-1.7-1.71.71.71.7-1.7-0.9-1.51.3-1.71.2-1.7-1.2-1.5
Time in novel zone, hab. session 15.25.16.8-1.6-2.32.52.32.3-2.3-2.3-2.32.32.3-2.22.22.2-2.2-2.2-2.22.40.92.6-2.62.5-2.32.52.51.8
Total zone transitions, hab. session 10.10.11.20.1-0.1-0.30.00.0-0.1-0.1-0.10.10.1-0.10.10.1-0.1-0.1-0.1-0.00.4-0.50.3-0.51.1-0.5-0.50.9
Total locomotion distance, hab. session 10.20.30.70.1-0.60.70.50.5-0.5-0.5-0.50.50.5-0.60.60.6-0.6-0.6-0.60.6-0.10.7-0.80.6-0.50.70.80.7
Locomotion velocity, hab. session 10.10.20.30.4-0.40.40.30.3-0.4-0.4-0.40.40.4-0.40.40.4-0.4-0.4-0.40.5-0.10.4-0.40.5-0.30.50.50.6
Time in familiar zone, hab. session 20.90.93.90.2-0.61.40.50.5-0.6-0.6-0.60.50.5-0.60.60.6-0.6-0.6-0.60.9-1.01.3-1.71.2-1.51.32.00.7
Time in novel zone, hab. session 20.50.51.4-0.20.5-0.9-0.5-0.50.50.50.5-0.5-0.50.6-0.6-0.60.60.60.6-0.70.7-0.81.0-0.80.9-0.9-1.2-0.7
Total zone transitions, hab. session 20.10.20.70.20.2-0.6-0.3-0.30.20.20.2-0.3-0.30.2-0.2-0.20.20.20.2-0.30.1-0.60.5-0.60.8-0.7-0.60.3
Total locomotion distance, hab. session 20.30.41.11.10.7-0.6-0.6-0.60.60.60.6-0.7-0.70.7-0.6-0.60.60.60.6-0.6-0.8-0.50.5-0.50.5-0.4-0.3-0.3
Locomotion velocity, hab. session 20.50.71.21.10.9-0.8-0.8-0.80.90.90.9-0.9-0.90.8-0.8-0.80.80.80.8-0.8-0.8-0.80.8-0.80.7-0.7-0.6-0.5
Novel to familiar place preference ratio0.30.31.30.5-0.30.70.30.3-0.4-0.3-0.30.40.4-0.30.30.3-0.3-0.3-0.30.5-0.50.9-0.80.9-0.91.01.10.3
Novelty place preference0.30.41.30.2-0.40.80.40.4-0.4-0.4-0.40.40.4-0.40.40.4-0.4-0.4-0.40.6-0.30.9-0.80.9-1.01.01.10.2
Time in novel zone, NPP test0.50.52.40.5-0.20.90.20.2-0.2-0.2-0.20.30.3-0.20.20.2-0.2-0.2-0.20.5-0.71.1-1.11.0-1.31.11.50.0
Total zone transitions, NPP test0.30.52.21.20.5-1.2-0.3-0.30.30.30.3-0.4-0.40.4-0.4-0.40.40.40.4-0.5-0.2-1.11.1-0.71.5-0.6-1.00.4
Total locomotion distance, NPP test0.10.21.41.20.1-0.60.00.0-0.00.00.0-0.0-0.0-0.00.00.0-0.0-0.0-0.0-0.1-0.2-0.50.5-0.10.9-0.0-0.40.7
Locomotion velocity, NPP test0.20.32.00.9-0.1-1.00.30.3-0.2-0.2-0.20.20.2-0.20.20.2-0.2-0.2-0.2-0.00.3-0.91.0-0.21.4-0.2-1.01.0
Intraocular pressure0.30.42.70.9-0.10.70.00.0-0.1-0.1-0.10.30.3-0.10.20.2-0.2-0.2-0.20.3-1.70.3-1.00.4-0.50.61.41.1
Delta distance traveled before/after self-admin1.61.73.8-0.5-1.41.11.11.1-1.5-1.3-1.31.31.3-1.41.41.4-1.4-1.4-1.41.50.41.1-1.31.2-1.91.21.31.2
Delta ambulatory time before/after self-admin1.41.63.1-0.3-1.41.01.01.0-1.5-1.3-1.31.31.3-1.41.41.4-1.4-1.4-1.41.50.11.0-1.21.2-1.71.21.21.3
Parametrial fat weight23.846.479.28.97.4-6.8-7.1-7.17.27.27.2-7.0-7.07.0-7.0-7.07.07.07.0-6.9-7.7-6.46.3-5.95.2-5.4-4.9-5.2
Pavlov. Cond. lever latency0.50.61.7-1.2-0.71.10.70.7-0.6-0.6-0.60.70.7-0.70.70.7-0.7-0.7-0.70.70.51.3-0.90.8-1.30.80.8-0.3
Pavlov. Cond. magazine entry latency0.60.72.21.50.9-0.9-0.8-0.80.80.80.8-0.8-0.80.9-0.9-0.90.90.90.9-0.8-1.0-1.00.7-0.61.0-0.5-0.4-0.1
Pavlov. Cond. change in total contacts2.22.34.42.11.7-1.2-1.7-1.71.61.61.6-1.7-1.71.7-1.7-1.71.71.71.7-1.5-1.9-1.10.9-1.00.7-0.8-0.4-1.2
Pavlov. Cond. index score1.01.23.01.71.2-1.2-1.1-1.11.11.11.1-1.2-1.21.2-1.2-1.21.21.21.2-1.1-1.3-1.20.9-0.91.0-0.7-0.6-0.4
Pavlov. Cond. latency score0.81.02.41.61.1-1.1-1.0-1.01.01.01.0-1.0-1.01.0-1.0-1.01.01.01.0-1.0-1.1-1.10.8-0.81.0-0.7-0.6-0.3
Pavlov. Cond. lever contacts1.01.22.11.51.2-1.1-1.2-1.21.11.11.1-1.2-1.21.2-1.2-1.21.21.21.2-1.1-1.2-1.30.9-1.01.1-0.9-0.7-0.4
Pavlov. Cond. magazine entry number0.60.82.7-1.6-1.00.90.90.9-0.9-0.9-0.90.90.9-1.01.01.0-1.0-1.0-1.00.91.10.8-0.70.5-0.60.40.40.4
Pavlov. Cond. intertrial magazine entries1.11.46.02.51.1-1.7-1.0-1.00.90.90.9-1.0-1.00.8-0.9-0.90.90.90.9-0.9-1.4-1.51.5-0.91.8-0.7-1.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.01.23.41.81.2-1.1-1.1-1.11.11.11.1-1.2-1.21.1-1.1-1.11.11.11.1-1.1-1.4-1.20.8-0.81.0-0.7-0.5-0.4
Pavlov. Cond. response bias0.70.92.11.51.0-1.1-0.9-0.90.90.90.9-0.9-0.90.9-0.9-0.90.90.90.9-0.9-0.8-1.20.9-0.81.1-0.7-0.6-0.2
Pavlov. Cond. lever latency0.81.14.4-2.1-1.10.70.90.9-1.0-1.1-1.11.01.0-1.11.11.1-1.1-1.1-1.11.02.10.5-0.50.4-0.20.20.10.7
Pavlov. Cond. magazine entry latency0.40.42.00.3-0.51.00.30.3-0.4-0.4-0.40.40.4-0.40.40.4-0.4-0.4-0.40.6-0.70.8-1.30.6-0.50.71.41.1
Pavlov. Cond. change in total contacts0.30.41.61.00.7-0.2-0.6-0.60.70.70.7-0.6-0.60.7-0.7-0.70.70.70.7-0.6-1.30.10.1-0.1-0.50.00.1-0.8
Pavlov. Cond. index score0.20.21.81.30.30.0-0.3-0.30.30.30.3-0.3-0.30.3-0.3-0.30.30.30.3-0.2-1.40.1-0.30.1-0.10.30.50.3
Pavlov. Cond. latency score0.20.21.81.40.3-0.1-0.3-0.30.30.40.4-0.3-0.30.4-0.4-0.40.40.40.4-0.3-1.30.0-0.10.1-0.10.20.30.2
Pavlov. Cond. lever contacts0.50.72.91.70.9-0.5-0.8-0.80.80.90.9-0.8-0.80.9-0.9-0.90.90.90.9-0.8-1.7-0.40.4-0.30.2-0.2-0.1-0.5
Pavlov. Cond. magazine entry number0.10.11.2-0.60.2-0.4-0.1-0.10.20.20.2-0.2-0.20.2-0.2-0.20.20.20.2-0.30.5-0.30.7-0.2-0.2-0.3-0.7-1.1
Pavlov. Cond. intertrial magazine entries3.74.87.52.02.3-2.7-2.1-2.12.12.12.1-2.2-2.22.1-2.1-2.12.12.12.1-2.3-1.5-2.52.7-2.22.2-2.1-2.6-2.1
Pavlov. Cond. lever-magazine prob. diff.0.10.11.21.10.10.1-0.1-0.10.10.20.2-0.1-0.10.2-0.2-0.20.20.20.2-0.1-1.10.2-0.40.2-0.10.30.60.4
Pavlov. Cond. response bias0.30.43.01.50.50.1-0.4-0.40.40.50.5-0.4-0.40.5-0.5-0.50.50.50.5-0.3-1.70.2-0.40.2-0.40.40.7-0.1
Time in closed arm before self-admin0.00.10.4-0.6-0.10.4-0.1-0.10.1-0.0-0.00.00.0-0.00.00.0-0.0-0.0-0.00.10.30.2-0.3-0.10.4-0.10.4-0.0
Time in closed arm after self-admin0.30.31.6-1.0-0.40.30.80.8-0.5-0.5-0.50.50.5-0.30.30.3-0.3-0.3-0.30.21.30.3-0.30.40.20.30.30.3
Time in open arm before self-admin0.60.61.9-1.4-0.70.81.01.0-0.7-0.7-0.70.90.9-0.70.70.7-0.7-0.7-0.70.70.80.7-0.70.8-0.80.70.30.5
Time in open arm after self-admin0.40.42.7-0.50.21.0-0.1-0.10.40.40.4-0.2-0.20.3-0.3-0.30.30.30.3-0.0-0.91.0-0.80.5-1.60.60.8-1.2
Bone: periosteal estimation7.716.022.14.74.3-4.2-4.0-4.04.24.24.2-4.1-4.14.1-4.1-4.14.14.14.1-4.2-3.7-4.14.0-3.63.6-3.4-3.4-2.9
Bone: periosteal perimeter11.318.822.14.14.7-4.2-4.5-4.54.74.64.6-4.6-4.64.6-4.6-4.64.64.64.6-4.6-3.8-4.14.1-4.13.4-3.9-3.5-3.9
Bone: post-yield work0.60.85.62.40.9-0.9-0.7-0.70.70.80.8-0.8-0.80.9-0.9-0.90.90.90.9-0.8-1.3-0.90.6-0.30.7-0.1-0.10.1
Progressive ratio test 1 active lever presses0.90.91.9-1.4-1.00.91.11.1-1.1-1.1-1.11.21.2-0.90.90.9-0.9-0.9-0.90.81.10.8-0.70.8-0.20.70.31.0
Progressive ratio test 1 breakpoint0.60.72.0-1.4-0.90.80.90.9-0.9-0.9-0.91.11.1-0.70.70.7-0.7-0.7-0.70.71.00.7-0.60.6-0.10.50.20.8
Progressive ratio test 1 inactive lever presses0.50.61.2-0.1-0.80.70.90.9-0.8-0.9-0.91.01.0-0.80.80.8-0.8-0.8-0.80.70.10.7-0.60.8-0.10.80.51.1
Progressive ratio test 2 active lever presses0.70.71.2-0.10.8-0.8-0.8-0.80.80.70.7-0.7-0.70.9-0.9-0.90.90.90.9-1.0-0.2-0.90.9-1.01.0-1.1-1.0-0.9
Progressive ratio test 2 breakpoint0.60.71.20.10.8-0.8-0.8-0.80.70.70.7-0.6-0.61.0-1.0-1.01.01.01.0-1.1-0.3-0.90.9-1.01.0-1.1-1.1-0.7
Progressive ratio test 2 inactive lever presses0.00.00.20.40.1-0.2-0.2-0.2-0.0-0.0-0.00.10.10.1-0.1-0.10.10.10.1-0.1-0.4-0.00.20.00.20.1-0.1-0.3
Incentive Sensitization - Responses2.22.22.70.91.6-1.4-1.6-1.61.51.51.5-1.5-1.51.6-1.6-1.61.61.61.6-1.6-1.1-1.51.3-1.61.1-1.6-1.2-1.5
Incentive Sensitization - Breakpoint1.81.82.30.81.4-1.2-1.5-1.51.41.41.4-1.4-1.41.5-1.5-1.51.51.51.5-1.5-1.1-1.31.2-1.50.8-1.4-1.0-1.4
Sum of active levers in priming session hrs 5-60.10.10.6-0.40.00.3-0.1-0.10.0-0.1-0.10.20.20.0-0.0-0.00.00.00.00.0-0.80.2-0.20.1-0.60.10.3-0.3
Progressive ratio2.12.55.7-2.4-1.71.51.71.7-1.4-1.6-1.61.61.6-1.71.71.7-1.7-1.7-1.71.71.81.5-1.21.3-0.51.10.91.2
Food seeking constrained by brief footshock6.58.010.4-3.2-3.13.22.72.7-2.8-2.9-2.93.03.0-3.03.03.0-3.0-3.0-3.03.02.22.8-3.02.5-1.92.32.62.5
Seeking ratio, punishment vs. effort0.10.20.40.2-0.40.30.40.4-0.5-0.4-0.40.50.5-0.50.40.4-0.4-0.4-0.40.40.10.1-0.40.3-0.50.40.40.7
Retroperitoneal fat weight37.6123.7225.615.011.9-11.6-11.6-11.611.411.311.3-11.4-11.411.4-11.3-11.311.311.311.3-11.2-11.6-11.210.5-10.19.8-9.2-8.3-7.4
Reaction time number correct0.60.81.40.51.1-0.6-0.8-0.81.11.01.0-1.0-1.01.1-1.1-1.11.11.11.1-1.0-0.9-0.40.6-0.70.5-0.6-0.4-1.2
Reaction time mean minus median0.10.10.4-0.50.1-0.1-0.2-0.20.20.20.2-0.2-0.20.1-0.1-0.10.10.10.1-0.10.4-0.40.2-0.60.6-0.6-0.60.2
Reaction time mean minus median AUC0.50.62.1-1.00.5-0.6-0.5-0.50.70.70.7-0.7-0.70.6-0.6-0.60.60.60.6-0.70.8-0.90.9-1.21.2-1.4-1.5-0.3
Reaction time num false alarms0.20.32.81.70.3-1.1-0.2-0.20.10.10.1-0.2-0.20.1-0.1-0.10.10.10.1-0.2-0.4-1.10.9-0.40.9-0.3-0.40.7
Reaction time num false alarms AUC0.50.62.91.70.7-1.4-0.6-0.60.50.50.5-0.6-0.60.5-0.5-0.50.50.50.5-0.6-0.6-1.51.2-0.81.1-0.7-0.70.4
Reaction time trials correct on left0.60.81.40.51.1-0.6-0.8-0.81.11.01.0-1.0-1.01.1-1.1-1.11.11.11.1-1.0-0.9-0.40.6-0.70.5-0.6-0.4-1.2
Reaction time trials on left0.60.81.30.51.0-0.5-0.8-0.81.11.01.0-1.0-1.01.1-1.1-1.11.11.11.1-1.0-0.9-0.40.5-0.70.4-0.6-0.4-1.1
Reaction time mean1.21.64.8-2.2-1.51.51.21.2-1.3-1.3-1.31.21.2-1.31.31.3-1.3-1.3-1.31.31.51.1-1.40.7-0.70.50.81.4
Reaction time mean AUC1.31.76.0-2.4-1.51.51.31.3-1.3-1.3-1.31.21.2-1.31.31.3-1.3-1.3-1.31.31.81.1-1.30.6-0.70.50.61.3
Median of all reaction times1.52.15.6-2.4-1.71.61.41.4-1.5-1.5-1.51.41.4-1.51.51.5-1.5-1.5-1.51.41.71.2-1.60.8-0.70.61.01.7
Reaction time omissions0.30.51.0-0.3-0.71.00.60.6-0.6-0.6-0.60.40.4-0.60.60.6-0.6-0.6-0.60.7-0.20.9-1.00.6-1.00.70.90.8
Reaction time false alarm rate0.20.32.21.50.1-0.9-0.1-0.1-0.1-0.1-0.10.00.0-0.20.20.2-0.2-0.2-0.20.1-0.3-1.00.6-0.30.7-0.2-0.21.2
Reaction time premature initiation rate0.20.32.10.3-0.5-0.20.00.0-0.4-0.5-0.50.40.4-0.60.60.6-0.6-0.6-0.60.50.5-0.3-0.1-0.21.0-0.30.01.4
Reaction time premature initiations0.20.31.30.60.3-0.7-0.6-0.60.40.30.3-0.4-0.40.2-0.3-0.30.30.30.3-0.3-0.1-0.70.5-0.81.1-0.8-0.40.3
Std. dev. reaction times0.00.00.2-0.4-0.10.1-0.0-0.00.00.00.0-0.1-0.1-0.10.10.1-0.1-0.1-0.10.10.3-0.2-0.1-0.40.3-0.4-0.20.5
Reaction time trials completed0.60.81.30.51.0-0.5-0.8-0.81.11.01.0-1.0-1.01.1-1.1-1.11.11.11.1-1.0-0.9-0.40.5-0.70.4-0.6-0.4-1.1
Reaction time trials AUC0.91.32.10.81.3-0.8-1.1-1.11.31.31.3-1.3-1.31.3-1.4-1.41.41.41.4-1.3-1.1-0.60.8-0.90.6-0.8-0.6-1.5
Run reversals in cocaine runway, females0.30.31.1-0.6-0.50.80.30.3-0.4-0.5-0.50.30.3-0.50.50.5-0.5-0.5-0.50.60.10.8-0.70.4-1.00.40.70.3
Run reversals in cocaine runway, males0.30.31.9-1.2-0.6-0.20.70.7-0.6-0.5-0.50.50.5-0.50.50.5-0.5-0.5-0.50.31.4-0.10.20.0-0.2-0.2-0.50.4
Latency to leave start box in cocaine runway0.50.53.9-1.60.21.0-0.4-0.40.50.40.4-0.5-0.50.4-0.4-0.40.40.40.4-0.2-0.20.9-0.7-0.0-1.2-0.10.6-2.0
Latency to leave start box in cocaine runway, F0.40.53.4-0.60.50.3-0.8-0.80.70.70.7-0.7-0.70.6-0.6-0.60.60.60.6-0.4-0.60.4-0.1-0.3-1.0-0.30.3-1.8
Latency to leave start box in cocaine runway, M0.20.22.2-1.50.10.70.00.00.30.30.3-0.2-0.20.3-0.3-0.30.30.30.3-0.20.30.5-0.40.0-0.2-0.10.1-1.1
Std. dev. time between licks in bursts2.02.43.7-0.3-1.51.51.61.6-1.6-1.5-1.51.61.6-1.51.51.5-1.5-1.5-1.51.70.61.8-1.61.9-1.81.91.81.5
Total sessions with >9 infusions0.40.41.2-0.5-0.60.10.90.9-0.6-0.6-0.60.90.9-0.50.50.5-0.5-0.5-0.50.31.10.10.10.40.60.3-0.61.1
Short access day 1 total inactive lever presses1.51.72.70.3-1.31.11.41.4-1.4-1.4-1.41.51.5-1.31.31.3-1.3-1.3-1.31.30.11.3-1.11.6-0.91.61.11.5
Short access day 10 total inactive lever presses2.12.46.02.41.4-2.2-1.5-1.51.31.31.3-1.3-1.31.2-1.2-1.21.21.21.2-1.4-1.4-1.92.0-1.52.0-1.4-1.8-0.8
Short access day 1 total infusions1.21.33.3-0.6-1.10.81.51.5-1.2-1.2-1.21.51.5-1.11.11.1-1.1-1.1-1.11.01.20.8-0.61.10.11.00.31.8
Short access day 10 total infusions1.41.54.2-2.1-1.21.51.41.4-1.2-1.2-1.21.51.5-1.01.01.0-1.0-1.0-1.01.01.61.4-1.21.2-0.61.10.90.6
Short access total infusions1.21.32.4-1.5-1.21.01.51.5-1.2-1.2-1.21.61.6-1.01.01.0-1.0-1.0-1.00.91.51.0-0.71.0-0.30.90.21.3
Short access day 1 locomotion0.20.21.0-0.4-0.50.40.60.6-0.6-0.6-0.60.80.8-0.40.40.4-0.4-0.4-0.40.30.40.4-0.20.30.30.3-0.01.0
Short access day 10 total locomotion0.50.61.1-0.4-0.80.60.90.9-0.9-0.9-0.91.01.0-0.60.60.6-0.6-0.6-0.60.61.10.8-0.60.7-0.40.70.41.0
Short access total locomotion1.11.14.1-1.1-1.10.41.31.3-1.3-1.2-1.21.41.4-0.90.90.9-0.9-0.9-0.90.62.00.5-0.30.50.30.4-0.31.8
One hour access (0.3 mA shock)0.30.31.1-0.9-0.51.00.60.6-0.5-0.5-0.50.60.6-0.30.30.3-0.3-0.3-0.30.4-0.20.8-0.90.7-0.30.70.8-0.0
Compulsive drug intake0.10.11.01.0-0.1-0.00.10.1-0.1-0.1-0.10.10.1-0.10.10.1-0.1-0.1-0.10.2-0.7-0.1-0.10.30.20.40.20.4
One hour access (shock baseline)0.50.62.5-1.6-0.71.00.70.7-0.7-0.7-0.70.80.8-0.60.60.6-0.6-0.6-0.60.60.81.0-0.80.7-0.70.60.6-0.2
Social response proportion0.30.33.51.9-0.1-0.60.10.1-0.2-0.2-0.20.20.2-0.30.20.2-0.2-0.2-0.20.2-0.4-0.50.20.21.20.3-0.01.2
Social responses1.82.37.12.71.6-1.4-1.5-1.51.51.51.5-1.6-1.61.5-1.6-1.61.61.61.6-1.5-2.0-1.31.2-1.21.2-1.0-0.7-0.8
Social time0.10.20.50.30.3-0.2-0.7-0.70.30.30.3-0.6-0.60.3-0.3-0.30.30.30.3-0.3-0.6-0.20.1-0.50.2-0.50.0-0.6
Soleus weight3.610.519.03.13.2-3.9-3.1-3.13.13.03.0-3.1-3.13.0-3.0-3.03.03.03.0-3.3-1.8-3.93.9-3.54.4-3.5-3.8-1.9
Bone: stiffness2.84.47.62.82.2-2.6-2.1-2.12.02.02.0-2.1-2.12.0-2.0-2.02.02.02.0-2.1-1.5-2.42.4-1.92.3-1.8-2.1-1.3
Tibialis anterior weight0.30.92.51.01.0-0.9-1.2-1.21.01.01.0-1.1-1.10.8-0.9-0.90.90.90.9-0.8-0.8-0.60.9-0.70.4-0.7-0.6-1.6
Time to tail flick, vehicle, before self-admin0.10.11.21.10.00.0-0.1-0.10.0-0.1-0.1-0.1-0.1-0.20.20.2-0.2-0.2-0.20.2-0.90.2-0.00.30.00.50.3-0.1
Time to tail flick, vehicle, after self-admin0.60.71.50.60.8-0.9-1.0-1.00.80.70.7-0.8-0.80.8-0.8-0.80.80.80.8-0.8-0.4-0.70.8-0.80.4-0.8-0.6-1.2
Time to tail flick, test, before self-admin0.70.72.3-1.2-0.90.30.90.9-1.0-0.9-0.91.01.0-0.80.80.8-0.8-0.8-0.80.61.50.2-0.30.30.60.2-0.21.1
Time to tail flick, test, after self-admin0.10.11.01.00.20.0-0.4-0.40.20.30.3-0.1-0.10.2-0.2-0.20.20.20.2-0.1-0.90.3-0.10.1-0.80.20.2-0.4
Delta time to tail flick, vehicle, before/after SA3.53.44.90.41.9-1.6-2.0-2.01.92.02.0-1.9-1.92.1-2.1-2.12.12.12.1-2.1-0.7-1.71.6-2.20.5-2.2-1.6-2.0
Delta time to tail flick, test, before/after SA1.31.15.02.21.1-0.6-1.3-1.31.11.11.1-1.1-1.10.9-0.9-0.90.90.90.9-0.7-1.9-0.30.6-0.4-0.9-0.10.1-1.5
Tibia length0.30.82.41.40.9-1.0-0.8-0.80.90.80.8-0.8-0.80.8-0.8-0.80.80.80.8-0.8-1.1-1.00.9-0.81.5-0.7-0.8-0.0
Ambulatory time before self-admin0.20.31.6-1.2-0.2-0.20.20.2-0.0-0.2-0.2-0.0-0.0-0.20.20.2-0.2-0.2-0.2-0.01.2-0.40.4-0.41.1-0.6-1.00.2
Ambulatory time after self-admin2.52.74.0-2.0-1.91.31.61.6-1.8-1.8-1.81.71.7-1.91.91.9-1.9-1.9-1.91.81.61.0-1.21.1-1.00.90.81.8
Bone: tissue strength0.30.31.0-0.7-0.51.00.40.4-0.3-0.4-0.40.40.4-0.40.40.4-0.4-0.4-0.40.5-0.01.0-0.90.6-1.00.60.80.1
Total heroin consumption5.86.88.62.02.8-2.1-2.9-2.92.82.72.7-2.8-2.82.8-2.8-2.82.82.82.8-2.8-2.8-2.42.0-2.72.0-2.6-1.7-2.2
Bone: trabecular number1.32.06.52.51.5-1.3-1.3-1.31.41.41.4-1.3-1.31.4-1.4-1.41.41.41.4-1.3-2.1-1.31.1-0.91.2-0.7-0.7-0.5
Bone: trabecular spacing3.64.77.7-2.3-2.22.52.02.0-2.1-2.1-2.12.02.0-2.12.12.1-2.1-2.1-2.12.31.62.6-2.52.2-2.82.22.41.0
Bone: trabecular thickness12.214.617.54.24.1-3.9-3.9-3.93.93.93.9-3.9-3.93.9-3.9-3.93.93.93.9-4.0-3.8-3.93.7-3.73.6-3.4-3.1-2.7
Bone: trabecular tissue density2.33.34.2-1.3-2.01.51.81.8-1.9-2.0-2.01.91.9-2.02.02.0-2.0-2.0-2.02.01.51.6-1.51.8-1.51.71.41.6
Water consumed over 24 hours0.20.30.80.10.5-0.8-0.3-0.30.40.40.4-0.3-0.30.4-0.4-0.40.40.40.4-0.50.2-0.60.9-0.50.8-0.5-0.9-0.6
Number of responses in last shaping day0.80.81.5-0.8-0.90.91.21.2-1.0-1.0-1.01.21.2-0.90.90.9-0.9-0.9-0.90.80.60.9-0.71.0-0.40.90.41.1