Hub : Genes

Cdk17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Cdk17 0.09 0.06 9.0e-03 0.01 0.03 0.02 0.01 1.3e-01 8.8e-03 3.8e-02 4.8e-02
2 Brain gene expression Cdk17 0.11 0.06 3.6e-08 0.09 0.07 0.09 0.08 2.7e-08 1.9e-07 1.4e-08 3.1e-08
3 RMTg mRNA stability Cdk17 0.17 0.1 4.6e-03 0.03 0.08 0.04 0.06 5.1e-02 3.9e-03 4.2e-02 1.0e-02
4 PL gene expression Cdk17 0.45 0.12 3.2e-13 0.14 0.11 0.11 0.14 1.1e-15 2.4e-12 3.0e-12 6.9e-15
5 Adipose gene expression Cdk17 0.06 0.04 2.1e-04 0 0.02 0.02 0.01 8.9e-02 2.1e-03 5.7e-03 4.2e-02
6 pVTA gene expression Cdk17 0.4 0.14 3.2e-07 0.12 0.18 0.19 0.18 1.0e-05 3.0e-08 1.4e-08 1.9e-08
7 Brain mRNA stability Cdk17 0.39 0.11 4.8e-12 0.14 0.15 0.14 0.15 2.3e-13 6.7e-14 6.7e-13 6.2e-14
8 BLA mRNA stability Cdk17 0.19 0.09 1.2e-05 0.1 0.08 0.07 0.1 8.7e-06 4.6e-05 1.3e-04 5.3e-06
9 PL mRNA stability Cdk17 0.18 0.07 2.9e-07 0.08 0.07 0.08 0.08 1.8e-09 2.1e-08 2.3e-09 1.7e-09
10 IL gene expression Cdk17 0.2 0.1 1.5e-03 0.07 0.07 0.06 -0 9.5e-03 9.5e-03 1.4e-02 3.9e-01
11 NAcc mRNA stability Cdk17 0.12 0.07 6.6e-05 0.05 0.02 0.03 0.05 2.0e-06 1.2e-03 4.3e-04 3.8e-06
12 IL mRNA stability Cdk17 0.28 0.16 5.1e-03 0.09 0.05 0.06 0.1 4.4e-03 2.9e-02 1.4e-02 1.9e-03
13 Adipose mRNA stability Cdk17 0.14 0.07 1.5e-03 0.02 0.02 0.02 0.03 1.7e-03 9.1e-04 1.1e-03 4.6e-04
14 NAcc gene expression Cdk17 0.16 0.07 6.5e-06 0.04 0.05 0.05 0.05 3.2e-05 3.7e-06 1.3e-06 1.4e-06
15 Adipose alternative polyA XM_017594835.2 0.06 0.04 3.1e-03 0 0.02 0 0 1.8e-01 5.7e-03 8.4e-02 1.1e-01
16 Adipose alternative polyA XM_017594835.2 0.06 0.04 3.1e-03 0.01 0.02 0 0 6.5e-02 5.9e-03 8.1e-02 9.8e-02
17 Adipose alternative polyA NM_001108082.2 0.06 0.04 4.3e-03 0 0.01 0 0 1.9e-01 9.8e-03 1.6e-01 2.1e-01
18 Adipose alternative polyA XM_006241253.4 0.06 0.04 4.4e-03 0 0.01 -0 0 3.6e-01 7.6e-03 3.9e-01 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.30.51.40.6-0.61.20.20.80.0-0.8-0.8-0.9-0.50.8-0.5-0.50.30.70.7-0.7-0.7
Area under the delay curve0.30.41.4-1.20.8-0.90.8-0.20.90.3-0.00.3-0.10.2-0.3-0.3-0.3-0.6-0.60.60.6
BMI with tail0.72.16.1-1.2-1.22.50.82.3-0.1-1.8-2.2-1.9-0.82.1-1.6-1.70.60.40.4-0.5-0.5
BMI without tail1.02.06.4-2.5-2.42.4-0.71.5-1.5-1.2-1.5-1.30.11.3-0.4-0.7-0.8-1.1-1.11.01.1
Body weight2.18.730.4-5.5-5.35.2-2.41.5-4.2-2.1-2.5-2.12.21.8-0.1-0.4-2.4-2.2-2.11.92.0
Weight adjusted by age0.50.62.4-0.5-1.41.5-0.40.7-1.0-1.0-1.0-0.90.40.8-0.3-0.40.70.00.0-0.1-0.1
Bone surface0.10.10.70.2-0.00.40.20.90.3-0.1-0.2-0.1-0.80.3-0.3-0.30.00.00.00.00.0
Bone volume0.30.51.70.3-0.51.20.31.30.1-0.8-0.8-0.8-0.90.8-0.6-0.70.20.60.6-0.6-0.6
Breakpoint value in progressive ratio session0.30.31.01.00.8-0.50.40.40.60.70.60.8-1.0-0.50.10.2-0.10.30.3-0.3-0.3
Number of licking bursts0.50.61.10.8-0.10.80.50.70.3-1.0-0.7-1.0-0.40.7-0.9-0.91.01.01.0-1.0-1.0
Context. condit. distance diff. score0.20.21.2-0.1-1.10.9-0.60.3-1.1-0.2-0.2-0.20.3-0.00.30.2-0.1-0.2-0.20.20.2
Locomotion velocity, session 10.50.52.3-0.30.9-1.50.1-0.60.51.00.91.0-0.1-0.80.40.4-0.5-0.7-0.70.70.7
Locomotion distance, session 10.20.30.8-0.20.8-0.60.80.30.9-0.3-0.4-0.3-0.50.5-0.7-0.70.50.10.1-0.1-0.1
Locomotion velocity, session 20.20.31.5-1.2-0.2-0.3-0.0-0.8-0.30.20.10.11.0-0.20.30.3-0.3-0.5-0.50.50.5
Locomotion distance, session 21.92.65.8-0.80.70.52.11.31.6-2.0-2.3-2.0-0.92.4-2.2-2.31.90.90.9-0.9-0.9
Locomotion velocity, session 30.10.20.6-0.6-0.80.5-0.00.7-0.7-0.5-0.3-0.5-0.10.20.10.10.5-0.1-0.10.10.1
Locomotion distance, session 30.70.72.0-0.5-1.01.40.30.6-0.6-1.2-1.3-1.30.41.0-0.6-0.70.70.60.6-0.7-0.7
Stereotopy head waving bouts, day 30.91.12.91.61.7-0.61.20.61.6-0.1-0.2-0.1-1.50.5-0.9-0.71.01.11.1-1.0-1.0
Stereotopy head waving duration, day 30.30.42.00.61.4-1.10.50.31.00.50.60.5-1.0-0.4-0.10.10.10.00.00.00.0
Locomotion velocity, session 70.30.31.9-1.4-0.10.0-0.0-0.1-0.70.20.10.20.6-0.20.20.2-0.9-0.7-0.70.60.6
Locomotion distance, session 70.20.31.5-1.2-0.1-0.20.1-0.5-0.40.20.10.20.8-0.20.20.2-0.4-0.6-0.60.50.6
Stereotopy head waving bouts, day 71.31.52.3-1.0-0.4-0.4-1.3-1.2-1.31.31.41.21.3-1.51.41.5-0.8-1.3-1.31.21.2
Stereotopy head waving duration, day 70.91.12.2-0.6-0.6-0.3-1.4-1.1-1.21.11.21.01.1-1.41.41.5-0.5-0.9-0.90.90.9
Locomotion velocity, session 80.50.64.0-2.0-0.6-0.1-0.0-0.2-0.4-0.3-0.4-0.30.60.4-0.2-0.30.3-1.1-1.11.11.1
Locomotion distance, session 81.62.46.4-1.3-0.91.61.21.80.2-2.2-2.5-2.2-0.52.4-1.9-2.11.50.40.4-0.5-0.4
Degree of sensitization distance1.01.01.8-0.80.5-1.3-0.5-1.10.01.31.21.20.6-1.10.80.8-0.7-1.2-1.31.31.3
Degree of sensitization stereotypy1.82.03.4-0.9-0.7-0.4-1.7-1.6-1.61.41.61.31.8-1.81.81.9-0.8-1.2-1.21.21.2
Conditioned locomotion0.30.42.21.2-0.20.6-0.50.1-0.40.70.40.6-0.3-0.40.40.3-1.50.50.5-0.5-0.5
Cocaine response after cond. corrected1.31.45.3-2.3-1.0-0.4-1.0-1.9-0.70.40.40.32.1-0.40.70.6-0.5-1.5-1.51.41.4
Cocaine response after cond. not corrected0.80.94.4-2.1-0.4-0.7-0.5-1.4-0.30.20.30.11.5-0.30.30.3-0.2-1.2-1.21.21.2
Cocaine response before conditioning0.80.93.21.31.5-0.51.11.41.1-0.20.0-0.1-1.80.1-0.8-0.60.60.91.0-0.9-0.9
Saline control response0.30.40.9-1.00.7-0.7-0.1-0.30.20.70.40.80.1-0.40.30.3-0.9-0.7-0.70.70.7
Bone: connectivity density0.30.50.8-0.4-0.9-0.1-0.9-0.8-0.60.50.50.50.7-0.50.80.7-0.3-0.8-0.90.90.9
Bone: cortical apparent density0.70.94.00.0-2.02.0-1.10.2-1.4-0.8-1.2-0.80.90.9-0.1-0.3-0.30.40.4-0.4-0.4
Bone: cortical area0.40.63.3-0.1-1.51.8-1.00.6-1.4-0.6-0.5-0.50.40.20.20.2-0.20.20.3-0.3-0.3
Bone: cortical porosity1.01.12.4-1.00.2-0.7-0.6-0.6-0.51.31.31.30.4-1.21.31.4-1.5-1.2-1.11.21.2
Bone: cortical porosity0.40.41.3-0.70.3-0.4-0.1-0.1-0.20.80.80.8-0.1-0.70.70.9-1.1-0.7-0.70.70.7
Bone: cortical thickness0.50.83.0-0.2-1.71.5-1.6-0.2-1.70.1-0.00.11.0-0.30.80.8-1.0-0.1-0.10.00.0
Bone: cortical thickness1.21.44.0-0.3-1.40.1-2.0-1.3-1.61.01.11.01.3-1.21.61.6-1.2-0.9-0.90.90.9
Bone: cortical tissue density0.60.83.9-0.1-2.01.9-1.10.2-1.4-0.8-1.2-0.70.90.8-0.1-0.3-0.40.30.3-0.4-0.4
Condit. Reinf. active minus inactive responses2.12.36.51.82.4-1.22.21.52.5-0.4-0.2-0.4-2.60.6-1.4-1.21.21.21.2-1.1-1.1
Condit. Reinf. active-inactive response ratio1.82.05.72.12.4-0.91.91.22.1-0.20.1-0.2-2.20.2-1.0-0.70.61.41.4-1.4-1.4
Condit. Reinf. active responses1.92.49.51.33.1-2.42.31.02.90.20.30.2-2.50.3-1.1-0.81.40.60.6-0.5-0.5
Condit. Reinf. inactive responses0.50.53.5-0.31.2-1.90.5-0.61.00.70.60.7-0.4-0.30.10.20.6-0.5-0.50.60.6
Incentive salience index mean2.93.59.01.02.6-1.03.02.12.9-1.2-1.1-1.2-2.81.5-2.2-1.92.11.31.3-1.3-1.2
Condit. Reinf. lever presses2.33.16.7-0.21.20.12.62.02.0-2.0-1.9-2.0-1.82.1-2.3-2.22.41.01.0-1.0-1.0
Condit. Reinf. active minus inactive responses0.10.20.90.9-0.10.4-0.30.6-0.20.10.10.1-0.6-0.20.20.2-0.20.50.5-0.5-0.5
Condit. Reinf. active-inactive response ratio0.00.00.1-0.1-0.00.30.00.3-0.0-0.3-0.2-0.3-0.10.1-0.1-0.00.20.20.2-0.2-0.2
Condit. Reinf. active responses0.60.82.61.60.30.80.41.30.2-0.6-0.5-0.5-1.10.4-0.5-0.40.31.31.3-1.3-1.3
Condit. Reinf. inactive responses0.30.42.81.70.10.40.10.60.2-0.0-0.10.1-0.80.1-0.2-0.2-0.00.90.9-0.9-0.9
Condit. Reinf. lever presses0.70.92.9-0.5-1.30.8-1.6-0.6-1.60.70.50.71.1-0.71.11.0-1.7-0.5-0.50.40.4
Condit. Reinf. lever reinforcers received0.40.62.11.40.10.80.31.20.1-0.5-0.4-0.4-1.00.4-0.3-0.40.31.11.1-1.1-1.1
Conditioned reinforcement - actives1.01.02.20.91.00.51.51.30.9-0.9-0.4-0.9-1.30.5-1.2-1.00.31.21.2-1.2-1.2
Conditioned reinforcement - inactives0.40.51.2-1.10.1-0.7-0.3-0.8-0.40.50.70.50.7-0.70.40.4-0.7-0.8-0.80.80.8
Conditioned locomotion0.10.10.3-0.40.10.20.10.4-0.3-0.40.1-0.3-0.1-0.2-0.30.0-0.6-0.0-0.00.00.0
Patch foraging indifference point 0 sec1.01.63.1-0.5-0.7-0.6-1.8-1.2-1.11.51.31.50.9-1.31.61.4-1.7-1.3-1.31.31.3
Patch foraging indifference point AUC0.91.02.9-1.7-1.60.3-1.1-0.8-0.80.4-0.10.11.20.00.40.20.0-1.4-1.41.41.4
Delay disc. indifference point, 0s delay0.30.41.6-0.81.3-0.90.9-0.11.00.40.00.5-0.40.2-0.4-0.3-0.1-0.4-0.40.40.4
Delay disc. indifference point, 16s delay0.90.92.5-0.60.80.11.60.91.2-1.2-0.9-1.2-0.81.1-1.4-1.20.90.60.6-0.6-0.6
Delay disc. indifference point, 2s delay0.60.71.9-1.40.8-1.20.3-0.30.40.80.40.80.0-0.30.20.2-0.7-1.2-1.21.21.2
Delay disc. indifference point, 24s delay0.80.82.1-1.30.2-0.01.11.40.9-1.1-0.7-1.1-1.20.9-1.2-1.10.3-0.3-0.30.30.3
Delay disc. indifference point, 4s delay1.41.52.7-1.50.5-1.5-0.5-1.50.01.51.11.40.8-0.91.00.9-1.6-1.5-1.51.51.5
Delay disc. indifference point, 8s delay0.30.31.5-1.2-0.0-0.3-0.1-0.60.30.4-0.20.30.50.30.1-0.1-0.6-0.8-0.80.80.8
Indifference point function ln k0.20.31.20.41.1-0.50.4-0.00.10.30.50.4-0.3-0.60.10.4-1.00.40.4-0.4-0.4
Indifference point function log k0.20.31.20.41.1-0.50.4-0.00.10.30.50.4-0.3-0.60.10.4-1.00.40.4-0.4-0.4
Patch foraging total patch changes 0 sec1.11.73.6-0.5-1.0-0.5-1.9-1.3-1.31.51.21.51.0-1.21.61.4-1.7-1.3-1.31.31.3
Patch foraging total patch changes 12 sec1.31.74.4-1.5-2.10.8-2.1-0.9-1.70.70.20.61.6-0.41.30.9-1.1-1.5-1.51.51.5
Patch foraging total patch changes 18 sec0.91.12.7-0.5-0.9-0.3-1.6-1.3-0.91.30.91.11.2-1.01.21.0-1.1-1.0-1.11.11.0
Patch foraging total patch changes 24 sec1.72.13.9-1.6-1.1-0.5-1.8-1.2-1.21.40.81.41.2-0.91.51.2-1.3-2.0-2.02.02.0
Patch foraging total patch changes 6 sec0.50.81.3-0.4-0.1-0.8-1.0-0.5-0.21.11.01.10.0-0.80.80.8-0.9-1.1-1.11.21.1
Patch foraging time to switch 0 sec0.40.73.51.90.30.90.20.70.2-0.4-0.1-0.3-0.70.0-0.0-0.10.11.31.3-1.2-1.3
Patch foraging water rate 0 sec0.91.43.8-0.9-0.10.71.21.50.7-1.4-1.9-1.5-0.91.9-1.7-1.80.80.40.4-0.5-0.4
Patch foraging water rate 12 sec0.30.54.0-2.0-0.10.00.20.3-0.2-0.5-0.6-0.40.10.6-0.1-0.1-0.3-0.8-0.80.80.8
Patch foraging water rate 18 sec1.62.13.00.91.10.61.71.41.0-1.6-1.4-1.5-1.21.4-1.7-1.51.71.71.7-1.7-1.7
Patch foraging water rate 24 sec1.11.54.6-0.6-0.71.60.71.6-0.0-1.6-2.1-1.6-0.62.0-1.5-1.60.60.70.7-0.8-0.7
Patch foraging water rate 6 sec2.43.59.3-1.2-1.32.71.12.3-0.3-2.7-3.1-2.7-0.52.8-2.1-2.21.01.01.0-1.1-1.1
Seeking ratio, delayed vs. immediate footshock0.30.31.7-1.30.3-0.60.0-0.80.20.30.30.30.5-0.20.0-0.0-0.8-0.7-0.70.70.7
Distance traveled before self-admin0.60.72.91.0-0.91.1-0.10.4-0.1-0.8-1.1-0.80.11.0-0.3-0.61.70.70.7-0.7-0.7
Distance traveled after self-admin1.01.13.8-0.6-0.20.80.70.50.4-1.5-1.6-1.50.21.5-1.1-1.22.00.60.6-0.7-0.7
Extensor digitorum longus weight0.41.74.31.50.11.41.02.10.7-1.1-0.9-1.1-2.01.1-0.9-1.00.11.61.6-1.6-1.6
Bone: elastic displacement0.70.82.30.70.7-1.5-0.4-1.00.31.31.41.2-0.1-1.20.91.0-0.7-0.4-0.40.50.5
Bone: elastic work0.81.02.60.70.6-1.4-0.7-0.80.01.41.61.4-0.3-1.41.21.4-1.0-0.5-0.50.60.5
Bone: endosteal estimation1.22.64.51.40.90.71.91.91.5-1.6-1.2-1.6-1.81.4-1.8-1.72.11.71.7-1.6-1.6
Bone: endosteal perimeter0.61.22.4-0.1-0.81.50.51.40.1-1.5-1.5-1.5-0.61.4-1.3-1.41.20.70.7-0.7-0.7
Epididymis fat weight0.61.35.1-1.5-2.32.1-0.90.3-2.0-0.9-1.3-0.91.50.80.1-0.00.3-0.4-0.40.30.3
Delta time in closed arm before/after self-admin0.10.10.3-0.1-0.10.20.10.2-0.0-0.60.1-0.60.0-0.0-0.20.10.50.10.1-0.1-0.1
Delta time in open arm before/after self-admin1.00.91.6-1.1-0.3-0.6-0.9-1.1-0.41.20.71.10.9-0.61.00.8-1.3-1.1-1.11.11.1
Diff in mean of infusions in LGA sessions1.51.74.71.02.2-2.10.2-0.41.01.92.01.9-1.0-1.70.81.0-1.3-0.3-0.30.40.4
Delay discount exponential model param0.40.42.11.5-0.60.8-0.60.3-0.7-0.20.1-0.2-0.1-0.20.20.30.50.80.8-0.8-0.8
Extinction: sum of active levers before priming0.70.73.2-0.11.6-1.81.00.11.40.40.80.4-1.0-0.4-0.4-0.10.6-0.4-0.40.40.5
Active lever presses in extinction session 60.50.51.7-0.50.9-0.40.91.11.3-0.2-0.2-0.2-1.30.5-0.7-0.60.3-0.4-0.40.40.5
Bone: final force0.20.31.50.6-0.61.2-0.20.9-0.5-0.6-0.3-0.5-0.40.20.10.10.20.60.6-0.6-0.6
Bone: final moment0.20.31.00.5-0.31.0-0.00.9-0.3-0.6-0.2-0.5-0.50.20.00.10.20.60.6-0.6-0.6
Food consumed during 24 hour testing period1.11.32.6-1.6-0.1-0.9-0.8-1.4-0.71.00.91.01.3-1.00.91.1-1.2-1.4-1.41.41.4
Glucose0.10.10.4-0.10.10.40.10.20.2-0.5-0.6-0.4-0.10.6-0.5-0.50.30.30.3-0.3-0.3
Heart weight0.20.31.8-1.4-0.60.4-0.10.1-0.6-0.7-0.3-0.70.50.2-0.00.10.4-0.3-0.30.30.3
Delay discount hyperbolic model param0.50.52.41.5-0.50.9-0.30.5-0.5-0.5-0.1-0.5-0.3-0.0-0.00.00.71.01.0-1.0-1.0
Intermittent access intake day 1-15 change0.80.71.61.30.90.31.11.00.9-0.3-0.3-0.5-1.20.4-0.7-0.60.51.11.1-1.1-1.1
Intermittent access intake escalation0.30.30.90.90.9-0.10.70.40.50.20.30.1-0.7-0.2-0.1-0.1-0.00.60.7-0.6-0.6
Intermittent access intake escalation 20.40.41.71.01.3-0.50.90.50.90.40.40.4-1.1-0.3-0.1-0.2-0.10.60.6-0.6-0.6
Intermitt. access day 1 inactive lever presses4.54.812.5-1.01.9-3.5-0.8-2.80.32.83.12.81.0-2.71.82.1-1.8-2.0-2.02.02.0
Intermitt. access day 15 inactive lever presses3.94.27.3-1.80.8-2.6-1.0-1.9-0.72.42.72.31.1-2.61.92.0-1.6-2.4-2.42.42.5
Intermitt. access escalation Index0.70.61.50.8-0.3-0.4-0.9-0.7-0.70.81.20.80.4-1.21.01.2-0.9-0.2-0.20.20.2
Intermittent access day 1 total infusions0.40.41.0-1.00.9-0.71.00.51.0-0.7-0.3-0.6-0.50.4-1.0-0.80.3-0.3-0.30.30.4
Intermittent access day 15 total infusions0.91.03.1-0.41.4-0.31.81.21.4-1.0-0.6-1.0-1.10.8-1.4-1.20.80.30.3-0.3-0.3
Intermittent access terminal intake (last 3 days)1.41.54.2-0.51.4-0.22.01.61.7-1.4-1.0-1.3-1.51.2-1.8-1.61.10.40.4-0.4-0.4
Intermittent access total infusions1.82.05.7-0.91.7-0.52.41.42.0-1.6-1.1-1.5-1.41.3-2.1-1.91.40.40.4-0.4-0.3
Intermittent access day 1 locomotion0.50.63.2-1.8-0.1-0.5-0.4-0.8-0.3-0.20.2-0.11.0-0.2-0.10.2-0.5-1.1-1.11.01.0
Intermittent access day 15 total locomotion0.10.20.8-0.90.2-0.40.10.10.1-0.10.2-0.0-0.1-0.2-0.3-0.1-0.4-0.6-0.60.60.6
Intermittent access total locomotion0.20.21.2-1.10.5-0.60.40.10.4-0.40.1-0.3-0.10.0-0.6-0.3-0.2-0.5-0.50.50.5
Intermittent access standard deviation2.12.24.9-0.41.40.22.21.21.8-1.7-1.7-1.8-1.01.8-2.1-2.02.00.80.8-0.8-0.8
Left kidney weight0.82.39.4-2.5-3.12.5-1.70.6-2.6-0.9-0.7-0.91.30.30.40.3-0.7-1.2-1.21.11.1
Right kidney weight0.82.28.3-2.5-2.92.2-1.80.0-2.6-0.6-0.5-0.51.80.00.70.5-0.5-1.2-1.21.11.1
Cocaine induced anxiety1.11.33.6-0.9-0.9-0.0-1.5-1.6-1.70.70.80.81.9-1.11.31.4-0.6-1.0-1.00.90.9
Post-drug Anxiety0.20.21.2-0.0-0.50.3-0.4-0.7-0.7-0.0-0.20.11.1-0.00.50.40.6-0.00.0-0.0-0.0
Baseline Anxiety0.30.42.01.40.20.10.30.70.6-0.0-0.1-0.0-1.00.2-0.2-0.20.30.80.8-0.7-0.7
Tail length2.78.326.6-4.7-5.23.6-3.7-0.2-4.8-0.7-0.9-0.72.90.21.31.0-3.0-2.8-2.72.62.6
Length with tail3.512.940.3-6.3-6.34.6-4.3-0.4-5.9-1.1-1.5-1.04.20.41.41.1-3.4-3.3-3.33.13.1
Length without tail1.53.211.7-3.4-3.22.6-1.9-0.2-2.9-0.8-1.0-0.72.40.40.50.4-1.5-1.4-1.31.21.2
Times rat made contact with spout1.11.34.00.12.0-0.61.91.22.0-0.6-0.5-0.5-1.60.8-1.4-1.20.80.60.6-0.6-0.6
Lifetime Intake2.12.45.5-0.41.30.22.31.81.7-2.0-1.5-2.0-1.41.6-2.3-2.11.50.90.9-0.9-0.9
Liver weight, left0.50.82.6-1.6-0.90.2-0.6-0.5-1.10.50.10.41.1-0.30.60.6-0.5-1.3-1.31.21.3
Liver weight, right1.32.18.4-0.3-2.02.90.31.5-0.9-1.9-2.2-2.00.01.9-0.9-1.10.90.90.9-1.0-1.0
Locomotor activity0.50.81.9-1.4-1.21.4-0.81.2-1.20.3-0.30.3-0.20.10.40.3-1.2-1.0-0.90.90.9
Locomotor testing distance0.20.41.6-0.30.30.1-0.11.3-0.20.70.30.7-1.1-0.30.20.3-0.8-0.6-0.60.60.6
Locomotor testing rearing0.40.71.60.80.4-0.6-0.70.50.01.21.11.3-1.0-1.00.80.9-1.2-0.5-0.60.60.6
Locomotion in novel chamber0.50.71.6-1.11.2-0.91.30.91.1-0.4-0.4-0.4-1.10.6-0.9-0.80.2-0.5-0.50.50.6
Locomotion in novel chamber post-restriction0.10.20.7-0.8-0.0-0.20.4-0.30.3-0.3-0.3-0.40.40.4-0.2-0.30.5-0.4-0.40.40.4
Fecal boli incidents, locomotor time 10.40.51.9-1.0-1.41.2-0.5-0.0-0.5-0.8-0.9-0.70.60.9-0.3-0.5-0.2-0.3-0.30.20.2
Change in fecal boli incidents, locomotor task0.60.52.20.91.5-1.50.60.00.70.70.90.8-0.8-0.80.20.40.20.10.1-0.1-0.0
Time >=10cm from walls, locomotor time 10.80.82.00.6-0.1-0.3-1.1-0.6-0.81.41.11.40.4-1.21.31.4-0.8-0.5-0.50.60.5
Bouts of movement, locomotor time 10.70.81.51.0-0.01.20.50.60.1-0.9-0.9-1.0-0.30.9-0.7-0.71.01.21.2-1.2-1.2
Total resting periods, locomotor time 10.60.71.41.20.20.90.40.60.1-0.8-0.6-0.8-0.40.6-0.5-0.51.01.21.2-1.2-1.2
Rest time, locomotor task time 10.10.10.40.3-0.0-0.2-0.3-0.2-0.20.30.60.3-0.1-0.50.40.60.1-0.1-0.10.20.2
Distance moved, locomotor task time 10.40.52.10.61.4-0.50.90.81.10.20.10.3-1.20.0-0.6-0.5-0.40.40.4-0.4-0.4
Vertical activity count, locomotor time 10.70.82.40.50.50.80.81.50.6-0.6-1.1-0.6-1.21.0-1.0-1.00.00.80.8-0.9-0.8
Time >=10cm from walls, locomotor time 20.20.20.90.10.8-1.00.1-0.40.50.70.50.8-0.1-0.40.40.40.3-0.3-0.30.30.3
Bouts of movement, locomotor time 20.20.21.80.6-0.30.2-0.30.70.00.20.30.1-0.9-0.10.40.2-1.3-0.2-0.20.20.2
Total resting periods, locomotor time 20.30.31.50.9-0.10.4-0.01.10.3-0.10.0-0.2-1.20.10.1-0.1-1.00.20.2-0.1-0.1
Rest time, locomotor task time 21.21.44.32.10.40.80.91.60.6-0.9-0.5-0.9-1.60.6-0.8-0.60.91.61.6-1.5-1.5
Distance moved, locomotor task time 20.30.41.5-1.10.0-0.3-0.4-1.1-0.40.40.20.51.2-0.30.30.4-0.2-0.6-0.60.60.6
Vertical activity count, locomotor time 20.40.42.6-1.6-0.31.0-0.20.0-0.3-0.2-1.1-0.20.70.9-0.4-0.5-0.4-0.3-0.20.20.2
Light reinforcement 10.50.84.1-0.6-2.01.6-0.90.1-1.9-0.7-0.7-0.61.20.30.50.30.6-0.1-0.10.10.1
Light reinforcement 20.20.30.7-0.1-0.3-0.4-0.5-0.9-0.50.50.60.40.7-0.60.70.7-0.1-0.3-0.30.30.3
Bone: marrow area1.12.54.41.30.90.71.91.81.5-1.6-1.2-1.6-1.71.4-1.8-1.82.11.61.6-1.6-1.6
Bone: maximum diameter0.40.72.4-0.1-1.01.5-0.01.3-0.5-1.1-1.1-1.1-0.41.0-0.8-0.80.80.40.4-0.5-0.4
Bone: maximum force0.10.20.80.8-0.40.9-0.30.7-0.4-0.30.1-0.2-0.5-0.20.20.30.00.60.6-0.6-0.6
Bone: maximum moment0.10.20.70.8-0.10.6-0.10.8-0.2-0.20.2-0.2-0.7-0.20.20.30.00.60.6-0.6-0.6
Mean time between licks in bursts1.31.93.40.7-0.21.41.11.80.9-1.6-1.8-1.6-1.41.8-1.5-1.70.81.31.3-1.3-1.3
Mean num. licks in bursts0.60.74.0-0.32.0-1.71.20.21.50.60.50.7-1.0-0.2-0.2-0.0-0.1-0.3-0.30.30.4
Cd content in liver4.65.19.50.6-0.93.11.22.00.4-3.1-3.0-3.1-0.62.8-2.5-2.71.72.42.4-2.4-2.4
Co content in liver0.40.51.8-1.3-1.20.5-0.6-0.4-0.6-0.1-0.6-0.20.80.50.1-0.2-1.0-0.7-0.70.70.7
Cu content in liver0.60.71.9-1.4-0.90.4-0.9-0.6-0.80.70.20.60.8-0.30.60.5-1.4-1.1-1.11.11.1
Fe content in liver0.20.20.80.10.30.50.60.90.2-0.6-0.4-0.5-0.60.4-0.5-0.4-0.00.50.5-0.5-0.5
K content in liver1.11.02.4-0.70.2-0.7-0.7-0.9-0.21.51.11.50.5-1.01.01.0-1.5-1.1-1.11.11.1
Mg content in liver0.70.72.0-0.10.7-0.8-0.4-0.5-0.01.41.11.4-0.1-1.00.80.9-1.3-0.7-0.80.80.8
Mn content in liver0.20.30.90.81.0-0.10.50.70.50.30.20.3-1.0-0.1-0.00.1-0.40.50.5-0.5-0.5
Na content in liver2.93.15.9-0.8-0.4-0.8-1.7-1.5-1.42.31.92.31.3-2.02.22.1-2.4-1.7-1.71.71.7
Rb content in liver0.70.92.5-0.8-0.1-0.7-0.6-1.6-0.41.20.81.21.1-0.70.90.9-0.9-1.0-1.01.01.0
Se content in liver0.10.10.4-0.30.6-0.50.40.20.10.40.20.5-0.2-0.30.10.20.2-0.3-0.30.30.3
Sr content in liver0.60.63.1-1.8-0.5-0.2-0.2-0.7-0.7-0.30.4-0.31.1-0.50.30.4-0.1-1.0-1.00.90.9
Zn content in liver0.20.21.4-1.2-0.50.40.20.2-0.1-0.5-0.7-0.60.30.6-0.3-0.4-0.0-0.3-0.30.30.3
Bone: minimum diameter1.12.08.3-0.1-1.62.90.12.0-0.9-1.9-1.8-1.8-0.31.5-1.0-1.10.71.01.0-1.1-1.1
Time in familiar zone, hab. session 10.30.31.1-0.9-1.00.4-0.5-0.3-0.5-0.4-0.4-0.40.80.3-0.1-0.20.6-0.4-0.40.40.4
Time in novel zone, hab. session 10.50.52.51.61.0-0.20.40.00.50.30.40.3-0.5-0.40.10.2-0.30.90.9-0.9-0.9
Total zone transitions, hab. session 12.73.89.80.50.61.31.93.11.5-2.1-2.5-2.1-2.62.6-2.4-2.51.11.41.4-1.5-1.4
Total locomotion distance, hab. session 13.34.713.30.91.40.82.53.72.2-2.0-2.3-1.9-3.42.6-2.7-2.71.51.51.5-1.5-1.4
Locomotion velocity, hab. session 14.46.218.10.91.70.73.04.32.7-2.2-2.6-2.2-4.02.9-3.1-3.11.91.61.6-1.6-1.5
Time in familiar zone, hab. session 20.10.10.7-0.4-0.50.3-0.00.3-0.1-0.3-0.4-0.3-0.00.4-0.1-0.10.8-0.2-0.20.20.2
Time in novel zone, hab. session 20.20.21.20.60.4-0.5-0.2-0.30.10.40.70.4-0.2-0.70.30.3-1.10.20.2-0.1-0.1
Total zone transitions, hab. session 22.43.25.31.20.70.81.92.31.4-1.9-1.9-1.9-2.02.0-1.9-2.01.81.81.8-1.8-1.8
Total locomotion distance, hab. session 24.55.912.02.42.00.52.83.22.7-1.8-2.1-1.7-3.52.3-2.7-2.72.02.52.5-2.5-2.4
Locomotion velocity, hab. session 24.86.412.32.32.00.62.93.32.8-2.0-2.3-1.9-3.52.5-2.9-2.92.22.52.5-2.5-2.5
Novel to familiar place preference ratio3.63.76.3-2.3-0.5-1.5-1.7-2.0-1.02.01.62.11.7-1.71.51.4-2.2-2.5-2.52.52.5
Novelty place preference4.14.16.6-2.2-0.4-1.7-1.8-2.2-1.12.21.92.31.7-1.91.71.7-2.3-2.6-2.62.62.6
Time in novel zone, NPP test4.34.46.6-2.1-0.5-1.6-2.0-2.2-1.32.32.02.41.8-2.01.91.9-2.5-2.6-2.62.62.6
Total zone transitions, NPP test0.10.20.5-0.1-0.50.7-0.10.7-0.2-0.4-0.7-0.4-0.40.6-0.4-0.6-0.30.10.2-0.2-0.2
Total locomotion distance, NPP test1.21.74.80.91.5-0.11.62.01.7-0.7-1.0-0.6-2.21.2-1.6-1.60.80.90.9-0.9-0.9
Locomotion velocity, NPP test1.42.05.81.21.8-0.31.82.01.9-0.7-1.0-0.6-2.41.2-1.7-1.71.01.11.1-1.0-1.0
Intraocular pressure0.40.63.00.11.1-1.70.3-1.41.00.50.70.50.6-0.50.10.21.0-0.3-0.40.40.4
Delta distance traveled before/after self-admin0.20.20.6-0.70.50.30.70.20.2-0.7-0.4-0.70.10.3-0.5-0.40.10.40.5-0.5-0.5
Delta ambulatory time before/after self-admin0.20.21.1-0.61.0-0.30.7-0.00.5-0.2-0.0-0.3-0.10.0-0.5-0.2-0.20.30.3-0.3-0.3
Parametrial fat weight0.20.30.9-0.2-1.00.5-1.0-0.0-1.00.10.20.20.3-0.30.60.7-0.8-0.5-0.50.50.5
Pavlov. Cond. lever latency0.81.13.1-0.8-1.70.7-1.8-0.7-1.60.30.40.31.2-0.60.90.8-1.3-0.9-0.90.90.9
Pavlov. Cond. magazine entry latency2.63.35.72.21.10.92.01.91.4-1.6-1.5-1.6-1.81.5-1.7-1.71.52.42.4-2.4-2.4
Pavlov. Cond. change in total contacts3.03.26.42.02.4-0.12.51.42.2-1.0-1.1-1.0-1.71.3-1.7-1.51.82.22.2-2.2-2.2
Pavlov. Cond. index score1.92.45.01.11.60.12.21.41.8-1.3-1.3-1.4-1.41.4-1.7-1.61.91.71.7-1.7-1.7
Pavlov. Cond. latency score2.02.55.41.01.8-0.12.31.41.9-1.3-1.2-1.3-1.51.4-1.7-1.62.01.71.7-1.7-1.6
Pavlov. Cond. lever contacts0.80.92.90.11.4-0.41.70.91.4-0.6-0.7-0.7-1.00.9-1.1-1.01.10.70.7-0.7-0.6
Pavlov. Cond. magazine entry number2.73.36.0-2.1-0.9-1.0-1.9-1.7-1.31.71.61.71.5-1.61.71.7-1.7-2.4-2.42.42.4
Pavlov. Cond. intertrial magazine entries0.10.20.6-0.20.3-0.7-0.2-0.30.20.50.40.6-0.0-0.30.20.3-0.2-0.5-0.50.50.5
Pavlov. Cond. lever-magazine prob. diff.2.12.64.81.01.40.32.21.51.8-1.5-1.5-1.5-1.51.6-1.8-1.72.01.71.7-1.7-1.7
Pavlov. Cond. response bias2.02.44.91.41.60.22.21.61.7-1.2-1.1-1.2-1.81.3-1.6-1.51.51.71.8-1.7-1.7
Pavlov. Cond. lever latency0.20.31.70.10.00.10.60.60.6-0.8-0.5-0.8-0.60.7-0.6-0.61.30.20.1-0.1-0.1
Pavlov. Cond. magazine entry latency0.30.30.80.5-0.30.50.20.60.3-0.6-0.9-0.7-0.30.8-0.7-0.70.50.60.6-0.6-0.6
Pavlov. Cond. change in total contacts0.20.30.9-0.90.10.30.40.70.4-0.5-1.0-0.5-0.40.9-0.9-1.0-0.50.00.0-0.1-0.0
Pavlov. Cond. index score0.10.10.4-0.0-0.20.4-0.20.1-0.0-0.1-0.6-0.10.20.4-0.3-0.4-0.60.20.3-0.3-0.3
Pavlov. Cond. latency score0.00.10.40.1-0.00.1-0.10.00.10.1-0.40.10.10.2-0.3-0.3-0.60.20.2-0.2-0.2
Pavlov. Cond. lever contacts0.20.21.4-0.3-0.30.4-0.6-0.4-0.60.40.10.50.8-0.30.40.4-1.20.00.1-0.1-0.1
Pavlov. Cond. magazine entry number0.91.12.3-0.80.3-0.9-0.6-1.1-0.61.11.51.10.7-1.41.31.4-0.8-1.0-1.11.11.1
Pavlov. Cond. intertrial magazine entries1.11.44.30.1-1.71.0-2.0-0.4-2.10.80.90.90.9-1.11.61.5-1.5-0.6-0.60.60.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.0-0.30.4-0.30.0-0.1-0.0-0.5-0.00.20.3-0.2-0.3-0.70.10.2-0.2-0.2
Pavlov. Cond. response bias0.10.20.9-0.1-0.60.9-0.30.0-0.4-0.2-0.7-0.20.50.4-0.2-0.3-0.50.40.4-0.4-0.4
Time in closed arm before self-admin0.70.81.71.0-0.91.30.10.9-0.6-1.0-0.8-0.9-0.30.6-0.3-0.50.41.21.2-1.2-1.2
Time in closed arm after self-admin0.70.72.20.2-0.91.50.20.9-0.5-1.5-0.8-1.4-0.00.7-0.5-0.41.00.80.8-0.8-0.8
Time in open arm before self-admin0.50.53.20.21.8-1.50.80.21.20.50.70.5-0.9-0.5-0.4-0.10.1-0.1-0.10.20.2
Time in open arm after self-admin1.31.43.3-0.50.8-1.4-0.7-1.1-0.01.81.41.80.3-1.31.11.0-1.6-1.1-1.11.21.2
Bone: periosteal estimation0.61.22.50.6-0.51.60.61.60.1-1.5-1.2-1.4-0.91.1-1.1-1.11.31.11.1-1.1-1.1
Bone: periosteal perimeter0.20.41.5-0.2-0.81.2-0.20.9-0.4-0.8-0.8-0.8-0.30.7-0.6-0.60.40.30.3-0.3-0.3
Bone: post-yield work0.10.10.3-0.2-0.2-0.2-0.3-0.3-0.30.10.50.10.4-0.60.40.50.5-0.2-0.20.20.2
Progressive ratio test 1 active lever presses0.70.72.7-1.60.7-0.01.20.60.8-1.1-0.9-1.1-0.20.9-1.2-1.00.4-0.3-0.30.30.4
Progressive ratio test 1 breakpoint1.21.32.9-1.30.70.31.61.11.1-1.6-1.4-1.6-0.51.4-1.7-1.51.10.10.1-0.1-0.1
Progressive ratio test 1 inactive lever presses0.91.02.1-0.70.5-1.3-0.5-1.0-0.31.01.41.10.4-1.30.71.0-1.2-1.1-1.11.11.1
Progressive ratio test 2 active lever presses1.82.05.5-0.51.40.02.31.51.7-1.7-1.2-1.7-1.21.3-2.1-1.81.50.80.8-0.8-0.8
Progressive ratio test 2 breakpoint1.71.95.1-0.41.40.22.31.51.6-1.7-1.2-1.8-1.21.3-2.0-1.81.50.90.9-0.9-0.9
Progressive ratio test 2 inactive lever presses0.81.04.1-1.12.0-1.51.70.51.6-0.30.4-0.3-0.9-0.1-0.9-0.60.9-0.5-0.50.50.5
Incentive Sensitization - Responses0.50.52.0-0.61.0-0.31.40.80.9-0.6-0.3-0.7-0.70.4-0.9-0.90.90.20.2-0.3-0.2
Incentive Sensitization - Breakpoint0.30.31.4-0.60.9-0.41.20.60.8-0.4-0.1-0.5-0.50.2-0.7-0.70.60.10.1-0.1-0.1
Sum of active levers in priming session hrs 5-60.90.81.5-0.10.30.91.00.80.6-1.1-1.2-1.1-0.31.1-1.2-1.20.90.90.9-0.9-0.9
Progressive ratio0.30.42.11.50.9-0.90.10.00.30.40.80.5-0.6-0.80.20.40.10.40.4-0.4-0.4
Food seeking constrained by brief footshock0.10.10.8-0.90.7-0.20.5-0.10.2-0.20.0-0.20.2-0.1-0.5-0.3-0.4-0.0-0.0-0.0-0.0
Seeking ratio, punishment vs. effort0.20.32.8-1.70.00.10.4-0.20.2-0.3-0.5-0.30.40.5-0.4-0.5-0.3-0.4-0.40.40.4
Retroperitoneal fat weight0.41.24.2-1.4-1.72.1-0.41.3-1.3-1.2-1.5-1.20.11.2-0.7-0.8-0.6-0.2-0.10.00.1
Reaction time number correct0.10.11.4-0.40.3-0.10.00.1-0.20.20.40.2-0.2-0.4-0.00.1-1.2-0.3-0.30.20.3
Reaction time mean minus median0.20.30.90.80.3-0.7-0.5-0.10.20.90.90.8-0.5-0.70.50.6-0.4-0.1-0.10.20.2
Reaction time mean minus median AUC0.20.31.30.70.9-1.00.30.21.10.40.30.2-0.9-0.1-0.2-0.10.60.20.2-0.1-0.1
Reaction time num false alarms1.72.44.8-0.40.8-1.8-1.0-1.8-0.22.22.12.20.8-2.01.81.8-1.3-1.3-1.31.41.4
Reaction time num false alarms AUC2.43.37.1-0.31.0-2.2-1.1-2.0-0.22.72.52.70.8-2.32.12.1-1.6-1.5-1.51.61.6
Reaction time trials correct on left0.10.11.4-0.40.3-0.10.00.1-0.20.20.40.2-0.2-0.4-0.00.1-1.2-0.3-0.30.20.3
Reaction time trials on left0.10.21.5-0.30.3-0.2-0.00.1-0.20.30.50.2-0.2-0.50.00.2-1.2-0.3-0.30.30.3
Reaction time mean0.91.24.02.00.40.40.61.01.0-0.5-0.8-0.6-1.30.9-0.8-0.91.01.51.4-1.4-1.4
Reaction time mean AUC0.60.83.51.90.30.40.40.80.8-0.2-0.5-0.4-1.20.6-0.6-0.70.51.21.2-1.2-1.2
Median of all reaction times1.41.94.02.00.40.91.11.41.2-0.9-1.4-1.1-1.41.4-1.2-1.31.31.81.8-1.8-1.8
Reaction time omissions0.81.03.82.01.3-1.4-0.1-0.10.61.41.61.3-1.0-1.30.81.0-0.10.20.2-0.1-0.1
Reaction time false alarm rate1.01.53.80.31.0-1.7-0.5-1.40.31.91.71.90.4-1.51.51.4-0.5-0.8-0.80.90.8
Reaction time premature initiation rate2.73.66.52.30.22.11.42.20.3-2.0-1.9-1.7-1.51.8-1.4-1.41.82.52.5-2.6-2.5
Reaction time premature initiations1.31.83.51.60.11.70.91.8-0.1-1.4-1.3-1.2-1.21.1-1.0-0.90.81.81.8-1.9-1.8
Std. dev. reaction times0.30.42.91.70.3-0.3-0.20.30.40.50.60.4-0.9-0.50.30.30.00.60.5-0.5-0.5
Reaction time trials completed0.10.21.5-0.30.3-0.2-0.00.1-0.20.30.50.2-0.2-0.50.00.2-1.2-0.3-0.30.30.3
Reaction time trials AUC0.10.11.0-0.30.40.10.30.40.0-0.10.1-0.1-0.4-0.1-0.4-0.2-1.00.00.0-0.0-0.0
Run reversals in cocaine runway, females6.46.110.81.6-1.02.81.82.60.9-3.3-3.1-3.2-1.43.1-2.6-2.72.92.52.5-2.5-2.5
Run reversals in cocaine runway, males3.73.66.0-1.40.9-2.3-0.9-1.9-0.52.52.52.31.3-2.41.81.9-1.4-2.1-2.12.12.2
Latency to leave start box in cocaine runway0.20.20.7-0.4-0.80.5-0.50.4-0.4-0.2-0.6-0.2-0.10.60.1-0.1-0.7-0.2-0.20.20.2
Latency to leave start box in cocaine runway, F0.10.10.30.1-0.0-0.6-0.3-0.20.10.50.10.5-0.2-0.10.30.2-0.5-0.3-0.30.30.3
Latency to leave start box in cocaine runway, M1.01.04.3-1.4-2.11.8-1.10.4-1.5-0.8-1.0-0.80.90.70.20.1-0.7-0.4-0.40.40.4
Std. dev. time between licks in bursts0.30.30.80.8-0.20.70.30.6-0.0-0.4-0.4-0.4-0.40.3-0.2-0.3-0.30.90.9-0.9-0.9
Total sessions with >9 infusions2.02.25.0-0.80.80.42.01.31.2-2.2-1.8-2.1-0.81.9-2.2-2.11.70.70.7-0.7-0.7
Short access day 1 total inactive lever presses0.70.83.5-0.71.4-1.90.4-0.80.70.61.30.60.1-1.00.10.40.5-0.8-0.80.90.9
Short access day 10 total inactive lever presses2.32.54.0-0.7-0.2-1.8-1.6-1.8-0.91.92.01.81.0-2.01.81.9-1.7-1.5-1.51.61.6
Short access day 1 total infusions4.04.38.10.70.71.42.32.31.4-2.8-2.2-2.8-1.52.2-2.7-2.52.21.91.9-2.0-1.9
Short access day 10 total infusions0.50.63.2-1.80.5-0.30.80.60.6-0.5-0.5-0.5-0.30.6-0.8-0.7-0.4-0.8-0.80.80.9
Short access total infusions3.33.77.1-0.10.71.42.32.31.3-2.7-2.3-2.6-1.42.3-2.7-2.51.81.41.4-1.5-1.4
Short access day 1 locomotion0.50.51.3-1.00.40.30.90.70.5-1.1-0.8-1.1-0.40.8-1.1-1.00.40.10.1-0.1-0.1
Short access day 10 total locomotion0.50.51.00.31.0-0.30.9-0.01.0-0.7-0.5-0.7-0.30.6-1.0-0.80.80.80.8-0.8-0.8
Short access total locomotion0.60.61.9-1.20.6-0.01.00.10.8-1.0-1.0-1.00.11.0-1.4-1.10.80.10.1-0.1-0.1
One hour access (0.3 mA shock)3.33.98.60.31.80.22.92.52.4-2.1-1.8-2.1-2.32.0-2.6-2.52.01.41.4-1.4-1.4
Compulsive drug intake0.10.10.10.4-0.40.2-0.30.3-0.2-0.0-0.3-0.0-0.20.20.10.1-0.40.30.3-0.3-0.3
One hour access (shock baseline)0.80.93.1-0.31.3-0.41.81.21.3-0.9-0.5-0.9-1.10.7-1.3-1.21.10.40.4-0.4-0.3
Social response proportion3.03.27.5-0.6-0.72.61.21.90.0-2.6-2.7-2.5-0.52.5-2.0-2.01.41.41.4-1.5-1.5
Social responses1.41.86.10.40.21.71.02.50.3-1.3-1.7-1.2-1.71.6-1.4-1.40.51.21.2-1.3-1.2
Social time0.81.12.10.70.70.51.21.41.2-0.9-0.8-1.0-1.41.0-1.1-0.91.41.01.0-0.9-0.9
Soleus weight0.41.34.20.0-1.42.00.21.0-0.5-1.7-1.6-1.60.11.5-0.8-0.81.40.80.7-0.8-0.8
Bone: stiffness0.91.55.91.1-0.72.40.11.8-0.4-1.2-1.1-1.2-0.90.9-0.6-0.7-0.11.51.5-1.5-1.5
Tibialis anterior weight0.82.97.02.60.61.11.42.11.4-1.4-0.9-1.3-2.51.2-1.1-1.10.52.32.3-2.2-2.2
Time to tail flick, vehicle, before self-admin0.70.72.5-0.1-1.51.6-0.30.5-0.6-1.3-1.4-1.10.31.2-0.4-0.70.60.30.3-0.4-0.4
Time to tail flick, vehicle, after self-admin1.31.43.70.80.70.31.30.21.2-1.2-1.2-1.2-0.31.3-1.3-1.31.91.41.4-1.4-1.4
Time to tail flick, test, before self-admin0.20.20.7-0.6-0.70.6-0.4-0.0-0.8-0.2-0.2-0.20.50.10.20.20.1-0.2-0.20.20.2
Time to tail flick, test, after self-admin0.60.61.51.0-0.31.20.21.0-0.2-1.0-0.5-1.0-0.40.5-0.6-0.50.61.01.0-1.0-1.0
Delta time to tail flick, vehicle, before/after SA0.60.62.7-0.11.6-1.11.3-0.51.4-0.10.0-0.2-0.10.2-0.8-0.60.90.40.4-0.4-0.4
Delta time to tail flick, test, before/after SA0.10.10.40.60.20.30.10.30.3-0.2-0.0-0.2-0.30.0-0.2-0.2-0.20.50.5-0.5-0.5
Tibia length1.95.422.3-2.1-3.44.7-0.32.0-2.3-3.1-3.4-3.11.12.7-1.7-2.10.70.80.8-1.0-0.9
Ambulatory time before self-admin0.50.52.60.7-0.70.90.10.40.0-0.8-0.9-0.80.10.9-0.3-0.51.60.60.6-0.6-0.6
Ambulatory time after self-admin1.01.12.8-0.8-0.61.00.40.60.1-1.7-1.6-1.70.31.5-1.0-1.11.70.50.5-0.5-0.5
Bone: tissue strength0.30.31.00.8-0.10.5-0.40.1-0.40.60.60.7-0.2-0.70.60.5-1.00.30.3-0.3-0.4
Total heroin consumption1.11.22.2-0.6-0.1-0.8-1.1-0.4-0.81.51.31.50.3-1.41.21.3-1.2-1.3-1.31.31.3
Bone: trabecular number0.10.10.80.9-0.40.5-0.10.1-0.1-0.2-0.1-0.1-0.10.20.10.10.40.40.4-0.4-0.4
Bone: trabecular spacing0.50.71.4-0.80.1-1.2-0.5-0.7-0.10.90.80.80.4-0.80.70.6-0.5-1.1-1.11.11.1
Bone: trabecular thickness0.50.73.2-0.4-1.71.8-0.50.3-1.1-0.9-1.0-0.90.60.7-0.1-0.30.10.30.4-0.4-0.4
Bone: trabecular tissue density0.30.50.80.60.80.30.80.60.7-0.4-0.7-0.4-0.50.6-0.8-0.80.30.90.9-0.9-0.9
Water consumed over 24 hours0.20.21.3-1.1-0.00.10.2-0.7-0.1-0.4-0.4-0.40.90.3-0.4-0.2-0.0-0.1-0.10.10.0
Number of responses in last shaping day0.30.31.4-0.91.2-1.01.00.10.8-0.20.3-0.2-0.2-0.1-0.6-0.2-0.0-0.4-0.40.40.5