Nckipsd

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Nckipsd 0.11 0.08 3.6e-07 0.05 0.04 0.05 0.05 1.7e-06 7.1e-05 8.5e-06 4.5e-06
2 NAcc isoform ratio XM_008766509.3 0.03 0.02 1.6e-03 -0 0 0 0 4.0e-01 1.5e-01 7.5e-02 2.3e-01
3 Brain alternative polyA NM_001393927.1 0.11 0.07 1.4e-08 0.09 0.09 0.08 0.08 9.5e-09 2.5e-08 5.5e-08 3.0e-08
4 Brain alternative polyA XM_006243754.4 0.11 0.07 1.3e-08 0.09 0.09 0.08 0.08 8.6e-09 2.4e-08 4.7e-08 3.2e-08
5 Brain alternative polyA NM_001393927.1 0.07 0.05 5.0e-06 0.06 0.06 0.06 0.06 3.2e-06 3.4e-06 3.7e-06 7.2e-06
6 Brain mRNA stability Nckipsd 0.05 0.04 3.1e-05 0.04 0.05 0.05 0.05 4.9e-05 2.7e-05 1.4e-05 2.3e-05
7 PL alternative polyA NM_001393927.1 0.06 0.03 7.9e-07 0.05 0.06 0.05 0.05 1.2e-06 9.7e-07 1.2e-06 1.5e-06
8 PL alternative polyA XM_006243754.4 0.06 0.03 6.1e-07 0.06 0.06 0.06 0.05 9.0e-07 8.2e-07 9.3e-07 1.2e-06
9 NAcc isoform ratio NM_001393927.1 0.06 0.04 1.6e-06 0.05 0.04 0.04 0.04 4.7e-06 2.9e-05 2.3e-05 3.4e-05
10 PL isoform ratio XM_008766509.3 0.03 0.02 2.7e-03 0.01 0.02 0.02 0.02 1.3e-02 1.7e-03 1.8e-03 1.3e-03
11 PL alternative polyA NM_001393927.1 0.06 0.03 1.1e-06 0.05 0.05 0.05 0.05 6.0e-06 3.4e-06 2.9e-06 2.8e-06
12 PL isoform ratio NM_001393927.1 0.05 0.03 4.7e-06 0.04 0.05 0.05 0.05 2.3e-05 4.9e-06 4.2e-06 4.4e-06
13 NAcc alternative polyA XM_006243754.4 0.09 0.06 2.7e-10 0.09 0.08 0.07 0.08 4.6e-10 1.0e-09 5.0e-09 3.6e-09
14 NAcc alternative polyA NM_001393927.1 0.09 0.06 4.0e-10 0.09 0.08 0.07 0.08 4.6e-10 1.6e-09 5.4e-09 4.1e-09
15 NAcc alternative polyA NM_001393927.1 0.09 0.06 4.4e-10 0.08 0.07 0.07 0.08 1.2e-09 4.5e-09 4.4e-09 2.4e-09
16 NAcc alternative polyA XM_006243754.4 0.08 0.05 6.4e-09 0.07 0.07 0.06 0.07 6.6e-09 1.6e-08 7.3e-08 2.3e-08
17 PL mRNA stability Nckipsd 0.05 0.03 9.2e-06 0.05 0.05 0.05 0.05 5.1e-06 5.5e-06 8.2e-06 7.2e-06
18 Brain alternative polyA XM_006243754.4 0.09 0.06 4.9e-06 0.06 0.05 0.05 0.06 1.5e-06 1.3e-05 1.1e-05 7.0e-06
19 Brain isoform ratio XM_008766509.3 0.09 0.06 1.7e-06 0.07 0.06 0.06 0.07 1.7e-07 1.4e-06 3.1e-06 4.8e-07
20 Brain gene expression Nckipsd 0.13 0.12 2.8e-04 0.01 0.02 0.03 0.02 3.8e-02 5.2e-03 9.8e-04 4.4e-03
21 PL alternative polyA XM_006243754.4 0.05 0.03 2.7e-05 0.04 0.04 0.04 0.04 3.2e-05 8.2e-05 5.9e-05 7.9e-05
22 BLA alternative polyA NM_001393927.1 0.09 0.06 1.7e-03 0.07 0.01 0.03 0.06 1.8e-04 6.8e-02 8.5e-03 5.1e-04
23 BLA alternative polyA NM_001393927.1 0.11 0.07 2.7e-04 0.09 0.03 0.04 0.08 2.6e-05 1.7e-02 2.4e-03 6.2e-05
24 BLA isoform ratio XM_008766509.3 0.07 0.06 5.3e-03 0.04 0.03 0.02 0.03 3.0e-03 1.4e-02 2.7e-02 6.8e-03
25 Brain isoform ratio NM_001393927.1 0.09 0.06 3.3e-05 0.05 0.05 0.05 0.05 1.1e-05 4.0e-05 3.1e-05 1.2e-05
26 BLA alternative polyA XM_006243754.4 0.09 0.06 1.6e-03 0.07 0.01 0.03 0.06 1.7e-04 5.2e-02 8.4e-03 4.7e-04
27 BLA mRNA stability Nckipsd 0.08 0.06 1.0e-03 0.02 0.02 0.02 0.02 1.8e-02 1.9e-02 4.3e-02 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.10.10.50.2-0.70.2-0.20.20.20.3-0.30.1-0.20.1-0.1-0.10.10.1-0.10.1-0.0-0.00.60.4-0.4-0.40.4-0.40.4-0.7
Area under the delay curve1.81.92.7-1.40.8-1.21.2-1.2-1.21.6-1.6-1.4-1.41.5-1.41.5-1.5-1.51.5-1.31.21.2-0.51.5-1.5-1.51.5-1.51.5-1.6
BMI with tail0.51.64.71.4-1.01.5-1.51.51.0-1.31.31.41.4-1.41.5-0.80.80.8-0.80.6-0.8-0.82.2-1.21.21.2-1.21.2-1.21.9
BMI without tail1.83.86.41.9-2.02.2-2.22.22.1-1.91.92.22.0-2.12.1-1.71.71.7-1.71.7-1.8-1.82.5-1.71.71.7-1.71.7-1.72.2
Body weight5.824.129.85.4-4.05.4-5.45.44.6-5.55.55.15.3-5.25.3-4.54.54.5-4.54.6-4.5-4.54.6-4.84.84.8-4.84.8-4.84.9
Weight adjusted by age0.50.51.20.5-0.10.7-0.70.70.7-1.11.10.80.8-0.80.8-0.80.80.8-0.80.8-0.4-0.40.1-0.70.70.7-0.70.7-0.70.7
Bone surface0.10.20.3-0.20.1-0.20.2-0.2-0.30.4-0.4-0.3-0.40.4-0.40.4-0.4-0.40.4-0.40.50.50.20.5-0.5-0.50.5-0.50.5-0.5
Bone volume0.10.10.70.0-0.20.0-0.00.0-0.40.3-0.3-0.1-0.30.3-0.30.2-0.2-0.20.2-0.20.30.30.40.5-0.5-0.50.5-0.50.5-0.8
Breakpoint value in progressive ratio session0.40.51.10.2-0.80.3-0.30.30.1-0.20.20.70.8-0.80.6-0.50.50.5-0.50.4-0.6-0.60.5-1.01.01.0-1.01.0-1.00.6
Number of licking bursts0.20.31.7-0.61.2-0.60.6-0.6-0.80.1-0.1-0.5-0.20.2-0.20.4-0.4-0.40.4-0.50.40.4-1.3-0.20.20.2-0.20.2-0.20.4
Context. condit. distance diff. score0.00.00.0-0.00.0-0.00.0-0.0-0.0-0.10.10.10.1-0.10.0-0.10.10.1-0.10.1-0.1-0.10.0-0.00.00.0-0.00.0-0.0-0.1
Locomotion velocity, session 10.20.21.6-0.2-0.0-0.20.2-0.2-0.50.3-0.3-0.2-0.30.3-0.40.3-0.3-0.30.3-0.30.30.30.20.5-0.5-0.50.5-0.50.5-1.3
Locomotion distance, session 10.70.93.71.2-1.51.2-1.21.20.7-0.80.81.20.9-0.90.9-0.90.90.9-0.90.9-0.8-0.81.9-0.50.50.5-0.50.5-0.5-0.0
Locomotion velocity, session 20.20.30.7-0.40.5-0.40.4-0.4-0.80.4-0.4-0.5-0.40.4-0.50.6-0.6-0.60.6-0.60.70.7-0.00.4-0.4-0.40.4-0.40.4-0.7
Locomotion distance, session 20.20.20.90.0-0.40.0-0.00.00.00.4-0.40.0-0.40.3-0.30.3-0.3-0.30.3-0.30.40.41.00.7-0.7-0.70.7-0.70.7-0.7
Locomotion velocity, session 30.20.22.20.5-0.80.5-0.50.50.60.0-0.00.3-0.00.10.00.1-0.1-0.10.1-0.00.00.01.50.6-0.6-0.60.6-0.60.6-0.5
Locomotion distance, session 31.51.62.4-1.00.5-1.01.0-1.0-0.81.4-1.4-1.1-1.31.3-1.21.4-1.4-1.41.4-1.31.41.40.21.6-1.6-1.61.6-1.61.6-1.2
Stereotopy head waving bouts, day 30.30.40.90.10.60.1-0.10.1-0.3-0.60.60.30.5-0.60.5-0.20.20.2-0.20.2-0.3-0.3-0.8-1.01.01.0-1.01.0-1.00.9
Stereotopy head waving duration, day 30.30.40.70.40.00.4-0.40.40.3-0.70.70.50.6-0.60.6-0.60.60.6-0.60.6-0.7-0.7-0.5-0.90.90.9-0.90.9-0.90.8
Locomotion velocity, session 70.10.10.80.2-0.80.2-0.20.20.90.2-0.20.1-0.10.1-0.1-0.10.10.1-0.10.2-0.1-0.10.70.5-0.5-0.50.5-0.50.5-0.1
Locomotion distance, session 71.41.83.1-1.10.6-1.11.1-1.1-0.41.4-1.4-1.2-1.51.5-1.41.3-1.3-1.31.3-1.21.31.3-0.31.8-1.8-1.81.8-1.81.8-1.2
Stereotopy head waving bouts, day 70.00.00.1-0.1-0.2-0.10.1-0.1-0.00.3-0.3-0.0-0.30.2-0.2-0.00.00.0-0.0-0.1-0.0-0.0-0.00.3-0.3-0.30.3-0.30.3-0.3
Stereotopy head waving duration, day 70.30.40.70.7-0.80.7-0.70.70.6-0.50.50.80.5-0.60.5-0.70.70.7-0.70.6-0.7-0.70.6-0.50.50.5-0.50.5-0.50.3
Locomotion velocity, session 80.20.32.60.6-1.00.6-0.60.60.2-0.20.20.70.4-0.40.4-0.30.30.3-0.30.2-0.2-0.21.6-0.10.10.1-0.10.1-0.1-0.2
Locomotion distance, session 80.30.43.90.7-1.40.7-0.70.70.7-0.10.10.80.2-0.20.2-0.40.40.4-0.40.3-0.3-0.32.00.4-0.4-0.40.4-0.40.4-0.6
Degree of sensitization distance1.11.11.50.9-0.90.9-0.90.91.1-1.01.01.01.0-1.01.0-1.21.21.2-1.21.2-1.2-1.20.2-1.01.01.0-1.01.0-1.01.0
Degree of sensitization stereotypy0.10.10.50.3-0.70.3-0.30.30.50.1-0.10.2-0.1-0.0-0.0-0.30.30.3-0.30.2-0.3-0.30.50.3-0.3-0.30.3-0.30.3-0.4
Conditioned locomotion3.03.54.4-2.01.3-2.02.0-2.0-1.62.1-2.1-1.8-2.02.0-2.11.7-1.7-1.71.7-1.71.61.6-1.42.0-2.0-2.02.0-2.02.0-2.0
Cocaine response after cond. corrected0.70.82.10.40.20.4-0.40.4-0.4-1.01.00.61.0-1.00.8-0.70.70.7-0.70.6-0.7-0.7-0.4-1.41.41.4-1.41.4-1.40.6
Cocaine response after cond. not corrected2.22.54.01.4-0.81.4-1.41.40.5-1.81.81.51.8-1.81.6-1.51.51.5-1.51.4-1.5-1.50.7-2.02.02.0-2.02.0-2.01.1
Cocaine response before conditioning0.91.03.51.4-1.51.4-1.41.41.4-0.90.91.20.9-0.91.0-0.90.90.9-0.90.9-0.9-0.91.9-0.40.40.4-0.40.4-0.40.5
Saline control response1.11.53.81.3-2.01.3-1.31.31.9-0.90.91.21.0-1.01.0-1.41.41.4-1.41.4-1.5-1.51.3-0.60.60.6-0.60.6-0.60.7
Bone: connectivity density0.40.71.5-0.5-0.3-0.50.5-0.50.11.0-1.0-0.6-1.00.9-0.90.4-0.4-0.40.4-0.50.50.5-0.11.2-1.2-1.21.2-1.21.2-1.1
Bone: cortical apparent density0.30.40.7-0.50.3-0.50.5-0.5-0.40.7-0.7-0.5-0.70.6-0.70.5-0.5-0.50.5-0.50.40.4-0.40.7-0.7-0.70.7-0.70.7-0.8
Bone: cortical area0.20.31.9-0.51.4-0.50.5-0.5-1.1-0.10.1-0.6-0.10.2-0.20.5-0.5-0.50.5-0.40.60.6-1.0-0.30.30.3-0.30.3-0.30.0
Bone: cortical porosity0.20.20.8-0.3-0.5-0.30.3-0.30.20.7-0.7-0.3-0.50.5-0.50.1-0.1-0.10.1-0.00.10.1-0.00.7-0.7-0.70.7-0.70.7-0.9
Bone: cortical porosity0.40.51.4-0.6-0.3-0.60.6-0.60.00.9-0.9-0.5-0.80.7-0.80.3-0.3-0.30.3-0.20.30.3-0.21.0-1.0-1.01.0-1.01.0-1.2
Bone: cortical thickness0.30.61.40.30.90.3-0.30.3-0.4-0.90.90.20.8-0.70.7-0.20.20.2-0.20.3-0.2-0.2-0.5-1.21.21.2-1.21.2-1.21.1
Bone: cortical thickness0.00.00.1-0.00.2-0.00.0-0.0-0.2-0.00.00.00.0-0.00.00.1-0.1-0.10.1-0.1-0.0-0.0-0.2-0.10.10.1-0.10.1-0.10.0
Bone: cortical tissue density0.30.40.8-0.50.2-0.50.5-0.5-0.40.7-0.7-0.5-0.70.7-0.70.5-0.5-0.50.5-0.50.40.4-0.40.8-0.8-0.80.8-0.80.8-0.9
Condit. Reinf. active minus inactive responses0.00.00.20.20.50.1-0.10.10.1-0.40.4-0.20.2-0.10.2-0.00.00.0-0.00.1-0.0-0.0-0.5-0.20.20.2-0.20.2-0.20.1
Condit. Reinf. active-inactive response ratio0.20.20.50.30.50.3-0.30.30.2-0.70.7-0.10.5-0.40.5-0.20.20.2-0.20.4-0.3-0.3-0.5-0.60.60.6-0.60.6-0.60.2
Condit. Reinf. active responses0.00.00.3-0.20.4-0.20.2-0.2-0.2-0.00.0-0.2-0.00.0-0.00.1-0.1-0.10.10.00.10.1-0.6-0.20.20.2-0.20.2-0.20.2
Condit. Reinf. inactive responses0.30.30.7-0.70.2-0.80.8-0.8-0.60.8-0.8-0.4-0.70.5-0.60.5-0.5-0.50.5-0.60.50.5-0.30.5-0.5-0.50.5-0.50.5-0.1
Incentive salience index mean0.10.10.3-0.30.6-0.30.3-0.3-0.30.1-0.1-0.4-0.20.2-0.20.4-0.4-0.40.4-0.30.30.3-0.40.1-0.1-0.10.1-0.10.1-0.2
Condit. Reinf. lever presses1.11.51.8-1.31.1-1.31.3-1.3-1.21.3-1.3-1.1-1.21.2-1.21.3-1.3-1.31.3-1.21.31.3-0.81.1-1.1-1.11.1-1.11.1-0.9
Condit. Reinf. active minus inactive responses1.72.12.91.6-1.11.6-1.61.61.1-1.61.61.31.7-1.61.6-1.11.11.1-1.11.2-1.2-1.21.5-1.61.61.6-1.61.6-1.61.3
Condit. Reinf. active-inactive response ratio1.51.62.31.3-0.81.3-1.31.30.6-1.41.41.21.5-1.41.4-1.01.01.0-1.01.0-1.0-1.01.2-1.51.51.5-1.51.5-1.50.9
Condit. Reinf. active responses1.52.12.81.6-1.21.6-1.61.61.4-1.61.61.31.7-1.51.6-1.21.21.2-1.21.3-1.3-1.31.4-1.51.51.5-1.51.5-1.51.5
Condit. Reinf. inactive responses0.00.00.1-0.00.1-0.00.0-0.00.30.1-0.1-0.2-0.20.2-0.10.1-0.1-0.10.1-0.10.10.1-0.10.3-0.3-0.30.3-0.30.30.1
Condit. Reinf. lever presses2.02.73.71.9-1.31.9-1.91.91.3-1.81.81.51.9-1.81.9-1.31.31.3-1.31.4-1.3-1.31.9-1.71.71.7-1.71.7-1.71.5
Condit. Reinf. lever reinforcers received1.72.43.11.7-1.21.7-1.71.71.6-1.71.71.41.8-1.61.7-1.31.31.3-1.31.4-1.4-1.41.4-1.61.61.6-1.61.6-1.61.6
Conditioned reinforcement - actives0.20.20.6-0.70.4-0.70.7-0.7-0.80.6-0.6-0.5-0.40.4-0.50.6-0.6-0.60.6-0.50.30.3-0.40.2-0.2-0.20.2-0.20.2-0.6
Conditioned reinforcement - inactives1.01.14.0-1.02.0-1.11.1-1.1-1.70.6-0.6-1.3-0.70.8-0.71.3-1.3-1.31.3-1.21.01.0-1.60.2-0.2-0.20.2-0.20.2-0.4
Conditioned locomotion0.30.40.9-0.60.0-0.60.6-0.6-0.40.8-0.8-0.6-0.60.6-0.70.5-0.5-0.50.5-0.40.30.30.00.7-0.7-0.70.7-0.70.7-1.0
Patch foraging indifference point 0 sec1.01.75.51.5-1.91.3-1.31.32.3-1.21.21.11.1-1.11.2-1.41.41.4-1.41.6-1.4-1.41.3-0.80.80.8-0.80.8-0.81.2
Patch foraging indifference point AUC0.10.10.90.2-0.90.3-0.30.3-0.00.1-0.10.40.2-0.30.2-0.30.30.3-0.30.2-0.4-0.40.9-0.20.20.2-0.20.2-0.2-0.5
Delay disc. indifference point, 0s delay0.00.00.1-0.1-0.1-0.20.2-0.2-0.40.2-0.2-0.1-0.10.0-0.10.1-0.1-0.10.1-0.1-0.2-0.2-0.0-0.10.10.1-0.10.1-0.1-0.1
Delay disc. indifference point, 16s delay1.01.01.5-0.90.6-0.90.9-0.9-0.51.1-1.1-1.1-1.11.1-1.01.0-1.0-1.01.0-0.80.80.8-0.41.2-1.2-1.21.2-1.21.2-1.0
Delay disc. indifference point, 2s delay0.20.20.9-0.50.3-0.30.3-0.3-0.60.5-0.5-0.5-0.40.5-0.40.4-0.4-0.40.4-0.40.50.5-0.10.5-0.5-0.50.5-0.50.5-0.9
Delay disc. indifference point, 24s delay1.11.01.4-0.90.6-0.80.8-0.8-0.61.1-1.0-1.1-1.01.1-1.01.1-1.1-1.11.1-0.81.01.0-0.31.2-1.2-1.21.2-1.21.2-1.1
Delay disc. indifference point, 4s delay1.31.42.0-1.41.0-1.21.2-1.2-1.31.3-1.3-1.2-1.21.2-1.21.2-1.2-1.21.2-1.21.11.1-0.81.1-1.1-1.11.1-1.11.1-1.2
Delay disc. indifference point, 8s delay2.32.33.3-1.40.9-1.31.3-1.3-1.11.7-1.7-1.4-1.61.6-1.61.5-1.5-1.51.5-1.41.41.4-0.61.8-1.8-1.81.8-1.81.8-1.8
Indifference point function ln k0.50.81.4-0.20.7-0.50.5-0.5-0.00.6-0.6-0.8-0.90.9-0.71.0-1.0-1.01.0-0.91.01.00.01.2-1.2-1.21.2-1.21.2-0.1
Indifference point function log k0.50.81.4-0.20.7-0.50.5-0.5-0.00.6-0.6-0.8-0.90.9-0.71.0-1.0-1.01.0-0.91.01.00.01.2-1.2-1.21.2-1.21.2-0.1
Patch foraging total patch changes 0 sec1.22.05.01.6-1.71.4-1.41.42.2-1.31.31.21.3-1.31.4-1.41.41.4-1.41.7-1.5-1.51.2-1.11.11.1-1.11.1-1.11.5
Patch foraging total patch changes 12 sec0.91.21.81.2-1.21.1-1.11.11.3-1.11.11.01.1-1.11.1-1.21.21.2-1.21.3-1.2-1.20.8-1.01.01.0-1.01.0-1.00.9
Patch foraging total patch changes 18 sec2.02.63.81.5-1.91.6-1.61.61.8-1.31.31.51.7-1.61.6-1.71.71.7-1.71.8-1.7-1.71.2-1.61.61.6-1.61.6-1.61.2
Patch foraging total patch changes 24 sec2.63.24.42.1-1.71.9-1.91.91.7-1.81.81.72.0-1.91.9-1.61.61.6-1.61.7-1.7-1.71.5-1.91.91.9-1.91.9-1.91.5
Patch foraging total patch changes 6 sec0.20.31.70.5-1.20.5-0.50.51.3-0.20.20.40.2-0.30.3-0.50.50.5-0.50.7-0.6-0.60.80.1-0.1-0.10.1-0.10.1-0.0
Patch foraging time to switch 0 sec0.10.21.1-0.50.9-0.50.5-0.5-0.70.1-0.1-0.4-0.20.1-0.20.2-0.2-0.20.2-0.30.40.4-1.1-0.20.20.2-0.20.2-0.2-0.0
Patch foraging water rate 0 sec0.10.20.60.3-0.40.4-0.40.40.7-0.40.40.30.4-0.40.4-0.40.40.4-0.40.5-0.5-0.50.2-0.30.30.3-0.30.3-0.30.8
Patch foraging water rate 12 sec0.20.31.00.6-0.40.4-0.40.40.6-0.50.50.40.5-0.50.6-0.40.40.4-0.40.3-0.4-0.40.5-0.50.50.5-0.50.5-0.51.0
Patch foraging water rate 18 sec0.00.00.20.10.20.0-0.00.0-0.5-0.30.30.30.1-0.30.10.1-0.1-0.10.1-0.0-0.1-0.10.1-0.20.20.2-0.20.2-0.2-0.0
Patch foraging water rate 24 sec0.71.01.30.8-0.71.0-1.01.00.6-1.01.01.11.1-1.11.0-1.01.01.0-1.00.8-1.0-1.00.6-1.11.11.1-1.11.1-1.10.9
Patch foraging water rate 6 sec0.20.20.80.7-0.70.6-0.60.60.5-0.40.40.60.4-0.30.4-0.50.50.5-0.50.3-0.6-0.60.9-0.10.10.1-0.10.1-0.10.4
Seeking ratio, delayed vs. immediate footshock1.92.23.5-1.90.8-1.81.8-1.8-1.51.8-1.8-1.4-1.61.4-1.61.4-1.4-1.41.4-1.31.51.5-1.01.4-1.4-1.41.4-1.41.4-1.6
Distance traveled before self-admin0.30.31.2-0.31.1-0.20.2-0.2-0.7-0.10.1-0.5-0.40.5-0.40.4-0.4-0.40.4-0.20.90.9-0.70.5-0.5-0.50.5-0.50.5-0.9
Distance traveled after self-admin0.70.71.9-0.71.2-0.50.5-0.5-1.10.4-0.4-1.0-0.70.9-0.70.7-0.7-0.70.7-0.51.41.4-0.60.9-0.9-0.90.9-0.90.9-1.3
Extensor digitorum longus weight0.10.51.4-0.81.2-0.80.8-0.8-1.00.5-0.5-0.8-0.50.6-0.50.8-0.8-0.80.8-0.90.80.8-0.80.2-0.2-0.20.2-0.20.2-0.2
Bone: elastic displacement0.10.10.40.20.40.2-0.20.2-0.1-0.40.40.00.4-0.30.4-0.00.00.0-0.00.2-0.1-0.1-0.3-0.60.60.6-0.60.6-0.60.6
Bone: elastic work0.50.61.10.8-0.10.8-0.80.80.1-1.01.00.60.9-0.90.9-0.50.50.5-0.50.6-0.5-0.50.5-1.01.01.0-1.01.0-1.00.8
Bone: endosteal estimation0.00.10.30.1-0.60.1-0.10.10.50.0-0.00.2-0.0-0.1-0.0-0.30.30.3-0.30.3-0.2-0.20.30.2-0.2-0.20.2-0.20.2-0.2
Bone: endosteal perimeter1.12.33.3-1.51.3-1.51.5-1.5-1.61.5-1.5-1.5-1.61.6-1.61.5-1.5-1.51.5-1.51.61.6-1.01.6-1.6-1.61.6-1.61.6-1.8
Epididymis fat weight0.20.51.10.6-0.40.7-0.70.7-0.1-0.80.80.60.9-0.90.8-0.40.40.4-0.40.5-0.3-0.30.8-1.11.11.1-1.11.1-1.10.2
Delta time in closed arm before/after self-admin0.20.20.8-0.40.0-0.70.7-0.7-0.90.8-0.8-0.3-0.40.3-0.50.4-0.4-0.40.4-0.80.00.0-0.50.0-0.0-0.00.0-0.00.0-0.5
Delta time in open arm before/after self-admin0.20.21.20.3-0.40.5-0.50.51.1-0.40.40.1-0.10.10.1-0.40.40.4-0.40.6-0.1-0.10.50.6-0.6-0.60.6-0.60.60.1
Diff in mean of infusions in LGA sessions0.70.83.60.00.40.1-0.10.1-0.0-0.60.60.80.8-0.90.8-0.30.30.3-0.30.2-0.6-0.6-0.7-1.51.51.5-1.51.5-1.51.9
Delay discount exponential model param2.12.22.91.5-1.01.4-1.41.41.3-1.71.71.61.5-1.61.5-1.61.61.6-1.61.4-1.3-1.30.7-1.61.61.6-1.61.6-1.61.6
Extinction: sum of active levers before priming0.10.10.5-0.1-0.70.1-0.10.10.30.1-0.10.20.2-0.30.2-0.20.20.2-0.20.3-0.1-0.10.4-0.40.40.4-0.40.4-0.40.1
Active lever presses in extinction session 60.20.21.00.6-1.00.6-0.60.60.8-0.20.20.30.3-0.30.3-0.20.20.2-0.20.6-0.1-0.11.00.0-0.0-0.00.0-0.00.0-0.4
Bone: final force1.01.72.61.2-0.41.2-1.21.20.7-1.61.61.21.4-1.41.4-1.21.21.2-1.21.2-1.0-1.00.6-1.61.61.6-1.61.6-1.61.4
Bone: final moment1.32.23.31.4-0.51.4-1.41.40.8-1.81.81.41.7-1.61.6-1.31.31.3-1.31.3-1.1-1.10.7-1.81.81.8-1.81.8-1.81.6
Food consumed during 24 hour testing period1.31.62.11.4-1.01.4-1.41.41.2-1.41.41.21.3-1.31.4-1.11.11.1-1.11.2-1.2-1.21.1-1.21.21.2-1.21.2-1.21.2
Glucose0.30.41.50.8-1.20.7-0.70.70.1-0.30.30.70.6-0.60.5-0.70.70.7-0.70.5-0.6-0.61.2-0.40.40.4-0.40.4-0.4-0.5
Heart weight3.04.36.92.0-0.91.9-1.91.90.9-2.32.31.82.3-2.22.2-1.91.91.9-1.91.9-1.9-1.90.8-2.62.62.6-2.62.6-2.62.2
Delay discount hyperbolic model param2.02.12.91.5-0.91.3-1.31.31.3-1.71.71.51.5-1.51.5-1.61.61.6-1.61.4-1.3-1.30.6-1.51.51.5-1.51.5-1.51.6
Intermittent access intake day 1-15 change0.80.83.1-0.71.7-0.90.9-0.9-0.80.3-0.4-1.1-0.80.8-0.71.0-1.0-1.01.0-0.91.31.3-1.40.6-0.6-0.60.6-0.60.6-0.2
Intermittent access intake escalation0.90.92.6-0.71.6-0.80.8-0.8-0.50.4-0.4-1.1-0.80.9-0.81.0-1.0-1.01.0-0.81.31.3-1.30.8-0.8-0.80.8-0.80.8-0.2
Intermittent access intake escalation 20.30.31.70.01.3-0.20.2-0.20.1-0.30.3-0.7-0.20.4-0.10.5-0.5-0.50.5-0.20.90.9-0.90.2-0.2-0.20.2-0.20.20.5
Intermitt. access day 1 inactive lever presses0.00.00.10.20.10.2-0.20.2-0.1-0.10.10.20.2-0.20.2-0.10.10.1-0.1-0.1-0.1-0.10.0-0.20.20.2-0.20.2-0.20.1
Intermitt. access day 15 inactive lever presses0.40.52.2-0.71.5-0.70.7-0.7-0.90.3-0.3-0.9-0.50.6-0.50.7-0.7-0.70.7-0.81.01.0-1.10.2-0.2-0.20.2-0.20.2-0.1
Intermitt. access escalation Index0.00.00.20.1-0.40.2-0.20.20.20.1-0.1-0.1-0.00.1-0.0-0.20.20.2-0.20.1-0.1-0.10.40.2-0.2-0.20.2-0.20.2-0.2
Intermittent access day 1 total infusions0.00.00.1-0.3-0.2-0.20.2-0.2-0.00.1-0.10.00.1-0.1-0.1-0.10.10.1-0.10.0-0.1-0.10.2-0.10.10.1-0.10.1-0.1-0.0
Intermittent access day 15 total infusions0.40.50.9-0.70.9-0.70.7-0.7-0.30.4-0.4-0.9-0.60.7-0.70.7-0.7-0.70.7-0.50.90.9-0.60.7-0.7-0.70.7-0.70.7-0.3
Intermittent access terminal intake (last 3 days)0.20.20.5-0.50.5-0.50.5-0.50.00.3-0.3-0.6-0.40.5-0.50.4-0.4-0.40.4-0.30.70.7-0.30.5-0.5-0.50.5-0.50.5-0.2
Intermittent access total infusions0.40.50.7-0.80.7-0.80.8-0.8-0.40.6-0.6-0.8-0.60.7-0.70.7-0.7-0.70.7-0.50.80.8-0.40.7-0.7-0.70.7-0.70.7-0.5
Intermittent access day 1 locomotion0.10.10.2-0.5-0.0-0.30.3-0.3-0.40.4-0.4-0.2-0.10.1-0.20.2-0.2-0.20.2-0.20.10.10.10.0-0.0-0.00.0-0.00.0-0.4
Intermittent access day 15 total locomotion1.31.42.2-0.90.6-1.11.1-1.1-0.71.3-1.3-1.1-1.31.3-1.31.1-1.1-1.11.1-1.01.21.2-0.41.5-1.5-1.51.5-1.51.5-1.4
Intermittent access total locomotion1.41.62.3-1.10.6-1.21.2-1.2-0.81.4-1.4-1.2-1.31.4-1.41.2-1.2-1.21.2-1.11.31.3-0.41.5-1.5-1.51.5-1.51.5-1.5
Intermittent access standard deviation0.20.31.00.30.90.1-0.10.10.4-0.80.8-0.20.4-0.30.40.1-0.1-0.10.10.30.60.6-0.6-0.50.50.5-0.50.5-0.51.0
Left kidney weight0.82.18.21.9-2.21.8-1.81.81.4-1.21.21.61.4-1.41.5-1.21.21.2-1.21.4-1.3-1.32.9-1.01.01.0-1.01.0-1.00.9
Right kidney weight0.20.54.20.9-1.50.9-0.90.90.9-0.40.40.70.4-0.40.4-0.50.50.5-0.50.7-0.5-0.52.10.1-0.1-0.10.1-0.10.1-0.4
Cocaine induced anxiety0.00.00.3-0.50.5-0.10.1-0.1-0.0-0.10.1-0.20.00.00.00.1-0.1-0.10.1-0.0-0.1-0.1-0.4-0.10.10.1-0.10.1-0.10.4
Post-drug Anxiety0.00.00.2-0.40.2-0.20.2-0.2-0.30.0-0.00.20.1-0.10.0-0.00.00.0-0.0-0.1-0.3-0.3-0.3-0.20.20.2-0.20.2-0.20.2
Baseline Anxiety0.91.01.5-0.80.6-0.90.9-0.9-0.71.0-1.0-0.7-1.11.0-1.10.9-0.9-0.90.9-1.01.01.0-0.61.2-1.2-1.21.2-1.21.2-1.1
Tail length6.018.321.34.4-4.24.5-4.54.54.4-4.54.54.64.3-4.44.3-4.54.54.5-4.54.6-4.5-4.53.4-3.93.93.9-3.93.9-3.93.6
Length with tail8.029.334.85.9-4.95.7-5.75.75.3-5.95.95.65.6-5.65.6-5.55.55.5-5.55.7-5.5-5.54.3-5.15.15.1-5.15.1-5.14.5
Length without tail5.411.915.64.0-2.73.7-3.73.73.0-3.93.93.33.7-3.63.6-3.43.43.4-3.43.5-3.2-3.22.6-3.53.53.5-3.53.5-3.52.9
Times rat made contact with spout0.70.81.10.9-0.50.9-0.90.90.7-1.01.00.81.0-1.01.0-0.90.90.9-0.90.9-0.9-0.90.4-1.01.01.0-1.01.0-1.00.9
Lifetime Intake0.40.50.6-0.70.5-0.80.8-0.8-0.50.7-0.7-0.8-0.70.7-0.80.7-0.7-0.70.7-0.60.80.8-0.40.7-0.7-0.70.7-0.70.7-0.7
Liver weight, left0.10.20.90.1-1.00.1-0.10.10.80.1-0.10.40.0-0.10.0-0.50.50.5-0.50.5-0.6-0.60.20.1-0.1-0.10.1-0.10.1-0.1
Liver weight, right1.22.14.41.6-2.11.5-1.51.51.3-1.21.21.71.4-1.51.3-1.61.61.6-1.61.4-1.6-1.61.9-1.11.11.1-1.11.1-1.10.4
Locomotor activity5.28.29.73.1-2.83.1-3.13.13.1-3.03.03.02.9-2.92.9-3.03.03.0-3.03.1-3.1-3.12.4-2.52.52.5-2.52.5-2.52.5
Locomotor testing distance4.37.18.93.0-2.82.9-2.92.92.9-2.82.82.82.7-2.72.7-2.72.72.7-2.72.9-2.8-2.82.4-2.32.32.3-2.32.3-2.32.2
Locomotor testing rearing0.10.10.20.3-0.20.2-0.20.20.2-0.30.30.20.3-0.30.3-0.40.40.4-0.40.4-0.5-0.5-0.2-0.40.40.4-0.40.4-0.40.2
Locomotion in novel chamber0.10.20.4-0.20.6-0.30.3-0.3-0.10.1-0.1-0.3-0.50.4-0.40.4-0.4-0.40.4-0.30.50.5-0.70.5-0.5-0.50.5-0.50.5-0.4
Locomotion in novel chamber post-restriction0.30.41.21.0-1.10.8-0.80.80.9-0.60.60.70.5-0.60.6-0.60.60.6-0.60.8-0.6-0.60.8-0.30.30.3-0.30.3-0.30.2
Fecal boli incidents, locomotor time 10.90.91.70.7-0.80.6-0.60.60.8-0.90.91.00.9-1.10.9-1.01.01.0-1.00.9-1.0-1.00.2-1.21.21.2-1.21.2-1.21.3
Change in fecal boli incidents, locomotor task0.00.00.20.10.00.2-0.20.2-0.40.2-0.2-0.20.10.10.00.2-0.2-0.20.2-0.30.00.00.40.1-0.1-0.10.1-0.10.1-0.5
Time >=10cm from walls, locomotor time 10.60.70.9-0.40.3-0.60.6-0.6-0.20.8-0.8-1.0-0.80.9-0.81.0-1.0-1.01.0-0.70.90.9-0.11.0-1.0-1.01.0-1.01.0-0.8
Bouts of movement, locomotor time 10.30.31.00.3-0.30.3-0.30.30.2-0.30.30.50.6-0.60.6-0.50.50.5-0.50.4-0.5-0.50.1-0.80.80.8-0.80.8-0.81.0
Total resting periods, locomotor time 10.30.30.90.2-0.20.3-0.30.3-0.1-0.30.30.40.6-0.60.6-0.40.40.4-0.40.3-0.4-0.40.1-0.90.90.9-0.90.9-0.90.8
Rest time, locomotor task time 10.30.31.7-0.80.3-0.90.9-0.9-1.30.9-0.9-0.4-0.40.3-0.50.4-0.4-0.40.4-0.60.50.5-0.6-0.20.20.2-0.20.2-0.2-0.3
Distance moved, locomotor task time 10.91.02.11.3-0.61.3-1.31.31.2-1.41.40.91.0-0.91.1-0.90.90.9-0.91.1-1.0-1.00.7-0.70.70.7-0.70.7-0.70.8
Vertical activity count, locomotor time 10.70.81.31.0-0.81.0-1.01.01.1-1.11.11.10.7-0.80.8-1.11.11.1-1.10.9-0.9-0.90.7-0.50.50.5-0.50.5-0.50.6
Time >=10cm from walls, locomotor time 21.01.11.51.2-1.11.0-1.01.00.9-1.11.10.91.1-1.11.1-0.90.90.9-0.91.2-1.0-1.00.8-1.11.11.1-1.11.1-1.10.7
Bouts of movement, locomotor time 20.10.10.8-0.30.7-0.10.1-0.1-0.9-0.00.0-0.2-0.00.1-0.20.2-0.2-0.20.2-0.10.30.3-0.3-0.00.00.0-0.00.0-0.0-0.6
Total resting periods, locomotor time 20.20.21.3-0.60.8-0.40.4-0.4-1.10.3-0.3-0.4-0.30.3-0.40.4-0.4-0.40.4-0.40.50.5-0.40.2-0.2-0.20.2-0.20.2-0.8
Rest time, locomotor task time 20.10.10.5-0.4-0.4-0.20.2-0.2-0.70.3-0.30.30.1-0.2-0.0-0.30.30.3-0.3-0.2-0.4-0.4-0.1-0.40.40.4-0.40.4-0.4-0.1
Distance moved, locomotor task time 20.50.61.61.3-0.21.1-1.11.10.7-1.21.20.50.8-0.70.9-0.50.50.5-0.51.0-0.4-0.40.6-0.60.60.6-0.60.6-0.60.3
Vertical activity count, locomotor time 20.10.10.30.40.00.2-0.20.20.1-0.30.3-0.0-0.10.1-0.10.0-0.0-0.00.00.30.20.20.10.3-0.3-0.30.3-0.30.3-0.6
Light reinforcement 10.71.31.51.1-1.11.1-1.11.10.8-1.11.11.21.1-1.21.1-1.21.21.2-1.21.2-1.1-1.11.0-1.11.11.1-1.11.1-1.10.8
Light reinforcement 20.30.30.8-0.3-0.4-0.30.3-0.3-0.20.7-0.7-0.1-0.70.5-0.60.3-0.3-0.30.3-0.30.40.40.60.9-0.9-0.90.9-0.90.9-0.8
Bone: marrow area0.00.10.40.2-0.60.2-0.20.20.5-0.00.00.30.0-0.10.0-0.40.40.4-0.40.3-0.3-0.30.40.1-0.1-0.10.1-0.10.1-0.1
Bone: maximum diameter0.30.51.9-0.81.4-0.80.8-0.8-1.20.4-0.4-0.7-0.50.5-0.60.7-0.7-0.70.7-0.80.80.8-1.00.2-0.2-0.20.2-0.20.2-0.4
Bone: maximum force0.71.21.61.0-0.61.0-1.01.00.8-1.31.31.11.2-1.21.1-1.11.11.1-1.11.1-0.9-0.90.6-1.21.21.2-1.21.2-1.21.1
Bone: maximum moment0.81.42.01.1-0.61.1-1.11.10.8-1.41.41.11.3-1.31.3-1.11.11.1-1.11.1-1.0-1.00.6-1.31.31.3-1.31.3-1.31.3
Mean time between licks in bursts1.31.82.7-1.31.4-1.31.3-1.3-1.61.3-1.3-1.5-1.31.3-1.31.5-1.5-1.51.5-1.51.51.5-1.11.1-1.1-1.11.1-1.11.1-1.3
Mean num. licks in bursts0.70.82.61.2-1.61.2-1.21.21.2-0.70.71.00.7-0.70.7-0.90.90.9-0.91.0-1.0-1.01.6-0.20.20.2-0.20.2-0.2-0.0
Cd content in liver2.73.04.21.4-0.91.4-1.41.41.3-1.91.91.41.8-1.81.7-1.81.81.8-1.81.8-1.8-1.80.1-2.02.02.0-2.02.0-2.01.8
Co content in liver0.10.10.6-0.20.8-0.20.2-0.20.0-0.10.1-0.4-0.10.2-0.10.4-0.4-0.40.4-0.20.30.3-0.40.1-0.1-0.10.1-0.10.10.3
Cu content in liver4.25.16.52.1-2.52.1-2.12.12.3-2.02.02.52.2-2.32.2-2.62.62.6-2.62.4-2.5-2.51.7-2.22.22.2-2.22.2-2.22.2
Fe content in liver2.02.43.51.2-0.81.2-1.21.21.6-1.61.61.31.5-1.51.5-1.81.81.8-1.81.6-1.7-1.7-0.2-1.71.71.7-1.71.7-1.71.9
K content in liver1.31.32.21.0-1.51.1-1.11.10.9-0.90.91.51.1-1.21.1-1.11.11.1-1.11.0-1.1-1.11.5-1.11.11.1-1.11.1-1.11.0
Mg content in liver0.10.10.80.2-0.60.2-0.20.2-0.00.0-0.00.50.2-0.30.2-0.10.10.1-0.10.0-0.1-0.10.9-0.20.20.2-0.20.2-0.20.3
Mn content in liver0.40.52.31.0-1.31.0-1.01.00.8-0.40.40.80.5-0.50.5-0.50.50.5-0.50.5-0.5-0.51.5-0.00.00.0-0.00.0-0.0-0.2
Na content in liver0.40.41.30.5-0.90.5-0.50.51.1-0.40.40.60.4-0.50.5-0.80.80.8-0.80.8-0.8-0.80.2-0.30.30.3-0.30.3-0.30.6
Rb content in liver1.11.42.60.6-0.20.6-0.60.61.3-1.21.20.61.1-1.01.1-1.31.31.3-1.31.3-1.3-1.3-0.9-1.51.51.5-1.51.5-1.51.6
Se content in liver0.20.20.40.4-0.50.5-0.50.5-0.1-0.30.30.60.3-0.50.4-0.50.50.5-0.50.3-0.4-0.40.4-0.50.50.5-0.50.5-0.50.3
Sr content in liver0.10.10.90.3-0.30.3-0.30.3-0.10.0-0.00.20.1-0.10.10.1-0.1-0.10.1-0.10.10.10.90.1-0.1-0.10.1-0.10.1-0.1
Zn content in liver4.75.36.32.3-2.52.3-2.32.32.1-2.22.22.52.3-2.42.3-2.42.42.4-2.42.3-2.4-2.42.0-2.22.22.2-2.22.2-2.22.0
Bone: minimum diameter0.40.81.5-0.91.0-0.90.9-0.9-1.20.8-0.8-0.9-0.90.9-0.91.0-1.0-1.01.0-0.91.11.1-0.70.8-0.8-0.80.8-0.80.8-1.0
Time in familiar zone, hab. session 11.31.24.2-1.41.5-1.41.4-1.4-1.11.0-1.0-1.2-1.11.1-1.11.0-1.0-1.01.0-1.00.90.9-2.10.7-0.7-0.70.7-0.70.7-0.4
Time in novel zone, hab. session 10.60.51.41.0-0.81.0-1.01.01.0-0.90.90.70.7-0.70.7-0.70.70.7-0.70.6-0.6-0.61.2-0.30.30.3-0.30.3-0.30.4
Total zone transitions, hab. session 10.40.63.51.0-1.31.0-1.01.01.1-0.60.60.90.5-0.50.6-0.50.50.5-0.50.5-0.5-0.51.90.1-0.1-0.10.1-0.10.10.1
Total locomotion distance, hab. session 10.20.31.50.7-0.90.7-0.70.70.6-0.40.40.70.5-0.60.6-0.50.50.5-0.50.4-0.6-0.61.2-0.30.30.3-0.30.3-0.30.3
Locomotion velocity, hab. session 10.30.41.80.8-1.10.8-0.80.80.7-0.40.40.80.5-0.60.5-0.60.60.6-0.60.5-0.6-0.61.3-0.20.20.2-0.20.2-0.20.3
Time in familiar zone, hab. session 20.60.61.8-0.91.3-0.90.9-0.9-1.30.6-0.6-0.8-0.60.6-0.70.8-0.8-0.80.8-0.80.70.7-1.30.2-0.2-0.20.2-0.20.2-0.4
Time in novel zone, hab. session 20.10.10.40.2-0.50.2-0.20.20.60.0-0.0-0.0-0.00.1-0.0-0.20.20.2-0.20.2-0.0-0.00.30.3-0.3-0.30.3-0.30.3-0.3
Total zone transitions, hab. session 20.10.11.20.4-0.40.4-0.40.40.1-0.20.20.30.1-0.10.1-0.00.00.0-0.00.00.10.11.10.1-0.1-0.10.1-0.10.1-0.3
Total locomotion distance, hab. session 20.40.51.50.8-1.10.8-0.80.80.5-0.50.50.90.7-0.70.7-0.70.70.7-0.70.6-0.7-0.71.2-0.50.50.5-0.50.5-0.50.5
Locomotion velocity, hab. session 20.30.41.60.7-1.10.7-0.70.70.5-0.40.40.90.6-0.60.6-0.60.60.6-0.60.5-0.6-0.61.3-0.40.40.4-0.40.4-0.40.3
Novel to familiar place preference ratio0.70.74.10.9-2.00.9-0.90.91.5-0.10.10.80.2-0.30.3-1.01.01.0-1.00.9-0.8-0.81.50.3-0.3-0.30.3-0.30.3-0.2
Novelty place preference0.70.74.40.9-2.10.9-0.90.91.6-0.00.00.70.2-0.30.3-1.01.01.0-1.00.9-0.8-0.81.50.4-0.4-0.40.4-0.40.4-0.3
Time in novel zone, NPP test0.80.84.31.0-2.11.0-1.01.01.7-0.20.20.90.3-0.50.5-1.11.11.1-1.11.0-0.9-0.91.40.1-0.1-0.10.1-0.10.1-0.0
Total zone transitions, NPP test1.92.710.62.1-2.52.1-2.12.11.8-1.41.42.01.5-1.61.6-1.51.51.5-1.51.5-1.4-1.43.3-0.90.90.9-0.90.9-0.90.8
Total locomotion distance, NPP test1.11.63.41.4-1.61.4-1.41.41.1-1.11.11.51.3-1.31.3-1.21.21.2-1.21.1-1.2-1.21.8-1.11.11.1-1.11.1-1.11.0
Locomotion velocity, NPP test1.11.64.31.5-1.81.5-1.51.51.2-1.11.11.51.3-1.31.3-1.21.21.2-1.21.2-1.2-1.22.1-1.01.01.0-1.01.0-1.00.9
Intraocular pressure0.81.22.80.9-1.30.8-0.80.80.9-0.80.81.00.9-1.00.9-1.41.41.4-1.41.2-1.7-1.70.1-1.01.01.0-1.01.0-1.00.6
Delta distance traveled before/after self-admin0.00.10.1-0.3-0.00.1-0.10.10.00.3-0.3-0.3-0.10.2-0.10.2-0.2-0.20.2-0.00.30.30.30.3-0.3-0.30.3-0.30.3-0.1
Delta ambulatory time before/after self-admin0.40.40.90.5-0.80.9-0.90.90.5-0.50.50.60.7-0.60.7-0.60.60.6-0.60.8-0.6-0.60.9-0.50.50.5-0.50.5-0.50.4
Parametrial fat weight0.91.73.21.6-1.61.5-1.51.51.8-1.41.41.31.3-1.31.3-1.21.21.2-1.21.5-1.4-1.41.6-1.01.01.0-1.01.0-1.00.9
Pavlov. Cond. lever latency4.35.47.62.5-2.42.5-2.52.52.7-2.32.32.42.3-2.32.3-2.62.62.6-2.62.6-2.5-2.51.6-2.02.02.0-2.02.0-2.01.9
Pavlov. Cond. magazine entry latency5.57.19.7-2.93.1-2.92.9-2.9-3.02.6-2.6-2.8-2.62.6-2.63.0-3.0-3.03.0-2.92.82.8-2.42.2-2.2-2.22.2-2.22.2-1.9
Pavlov. Cond. change in total contacts1.51.62.8-1.41.7-1.41.4-1.4-1.41.2-1.2-1.4-1.21.2-1.21.4-1.4-1.41.4-1.41.31.3-1.60.9-0.9-0.90.9-0.90.9-0.7
Pavlov. Cond. index score5.36.79.3-2.83.1-2.82.8-2.8-2.92.5-2.5-2.7-2.52.5-2.52.9-2.9-2.92.9-2.82.82.8-2.42.0-2.0-2.02.0-2.02.0-1.7
Pavlov. Cond. latency score5.36.78.5-2.82.9-2.82.8-2.8-2.92.5-2.5-2.7-2.52.6-2.52.9-2.9-2.92.9-2.82.82.8-2.22.2-2.2-2.22.2-2.22.2-1.9
Pavlov. Cond. lever contacts2.22.63.6-1.71.8-1.71.7-1.7-1.91.6-1.6-1.6-1.51.6-1.61.9-1.9-1.91.9-1.81.81.8-1.11.3-1.3-1.31.3-1.31.3-1.1
Pavlov. Cond. magazine entry number6.27.810.33.1-3.23.1-3.13.13.1-2.82.82.92.8-2.72.8-3.13.13.1-3.13.0-2.9-2.92.7-2.22.22.2-2.22.2-2.21.9
Pavlov. Cond. intertrial magazine entries0.30.30.50.6-0.70.5-0.50.50.5-0.50.50.60.5-0.60.5-0.70.70.7-0.70.7-0.6-0.60.4-0.50.50.5-0.50.5-0.50.4
Pavlov. Cond. lever-magazine prob. diff.4.65.79.3-2.73.0-2.72.7-2.7-2.82.2-2.2-2.5-2.32.3-2.32.7-2.7-2.72.7-2.72.62.6-2.41.7-1.7-1.71.7-1.71.7-1.3
Pavlov. Cond. response bias5.76.910.1-2.93.2-2.92.9-2.9-3.02.5-2.5-2.7-2.52.5-2.53.0-3.0-3.03.0-2.92.82.8-2.52.0-2.0-2.02.0-2.02.0-1.7
Pavlov. Cond. lever latency0.20.30.8-0.70.4-0.70.7-0.7-0.30.7-0.7-0.4-0.70.6-0.70.3-0.3-0.30.3-0.40.40.4-0.90.6-0.6-0.60.6-0.60.6-0.4
Pavlov. Cond. magazine entry latency0.10.10.6-0.30.5-0.30.3-0.3-0.80.3-0.3-0.3-0.20.2-0.20.6-0.6-0.60.6-0.50.50.50.10.1-0.1-0.10.1-0.10.1-0.2
Pavlov. Cond. change in total contacts2.02.73.51.8-1.21.8-1.81.81.3-1.81.81.61.9-1.81.8-1.41.41.4-1.41.4-1.5-1.51.5-1.81.81.8-1.81.8-1.81.6
Pavlov. Cond. index score0.10.10.30.30.10.3-0.30.3-0.3-0.40.40.20.5-0.40.40.1-0.1-0.10.10.0-0.0-0.00.6-0.50.50.5-0.50.5-0.50.2
Pavlov. Cond. latency score0.10.10.30.30.10.3-0.30.3-0.3-0.30.30.10.4-0.30.30.2-0.2-0.20.2-0.00.00.00.5-0.40.40.4-0.40.4-0.40.2
Pavlov. Cond. lever contacts0.70.92.01.2-1.01.2-1.21.20.7-1.01.01.01.1-1.11.1-0.70.70.7-0.70.8-0.8-0.81.4-0.90.90.9-0.90.9-0.90.6
Pavlov. Cond. magazine entry number0.30.41.10.6-0.80.6-0.60.61.0-0.60.60.70.5-0.50.5-0.90.90.9-0.90.8-0.8-0.80.3-0.30.30.3-0.30.3-0.30.5
Pavlov. Cond. intertrial magazine entries0.50.71.6-0.90.9-0.90.9-0.9-0.00.7-0.7-0.9-0.91.0-0.90.6-0.6-0.60.6-0.60.70.7-1.30.9-0.9-0.90.9-0.90.9-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.30.10.3-0.30.3-0.4-0.40.40.20.4-0.40.40.1-0.1-0.10.1-0.10.00.00.6-0.40.40.4-0.40.4-0.40.2
Pavlov. Cond. response bias0.10.10.40.30.00.3-0.30.3-0.4-0.20.20.10.3-0.30.30.2-0.2-0.20.2-0.10.10.10.6-0.30.30.3-0.30.3-0.3-0.1
Time in closed arm before self-admin0.91.12.71.5-0.51.2-1.21.21.7-1.31.30.51.0-0.81.1-0.90.90.9-0.91.3-0.7-0.70.9-0.70.70.7-0.70.7-0.71.6
Time in closed arm after self-admin0.10.10.30.20.2-0.30.3-0.3-0.60.0-0.0-0.20.1-0.1-0.00.1-0.1-0.10.1-0.2-0.2-0.2-0.3-0.40.40.4-0.40.4-0.4-0.0
Time in open arm before self-admin0.60.71.5-1.20.7-0.90.9-0.9-1.20.9-0.9-0.6-0.80.7-0.80.9-0.9-0.90.9-1.00.80.8-0.80.6-0.6-0.60.6-0.60.6-0.9
Time in open arm after self-admin0.91.03.2-0.6-0.2-0.30.3-0.30.40.9-0.9-0.4-1.11.1-0.90.3-0.3-0.30.3-0.30.70.70.41.8-1.8-1.81.8-1.81.8-1.1
Bone: periosteal estimation0.00.00.1-0.00.2-0.00.0-0.0-0.2-0.10.10.00.1-0.10.0-0.00.00.0-0.00.00.10.1-0.1-0.10.10.1-0.10.1-0.1-0.0
Bone: periosteal perimeter1.11.82.8-1.41.6-1.41.4-1.4-1.71.2-1.2-1.4-1.31.3-1.41.4-1.4-1.41.4-1.41.51.5-1.31.2-1.2-1.21.2-1.21.2-1.5
Bone: post-yield work0.00.10.30.2-0.30.2-0.20.20.5-0.10.10.30.1-0.20.2-0.20.20.2-0.20.2-0.1-0.10.4-0.00.00.0-0.00.0-0.00.5
Progressive ratio test 1 active lever presses0.00.10.30.0-0.4-0.00.0-0.0-0.00.3-0.3-0.3-0.10.2-0.10.3-0.3-0.30.3-0.00.10.10.40.1-0.1-0.10.1-0.10.1-0.5
Progressive ratio test 1 breakpoint0.10.10.4-0.0-0.3-0.10.1-0.1-0.30.4-0.4-0.4-0.10.2-0.20.3-0.3-0.30.3-0.20.10.10.40.2-0.2-0.20.2-0.20.2-0.6
Progressive ratio test 1 inactive lever presses0.30.31.5-0.51.0-0.50.5-0.5-1.20.4-0.4-0.7-0.20.3-0.30.7-0.7-0.70.7-0.70.50.5-0.7-0.20.20.2-0.20.2-0.2-0.2
Progressive ratio test 2 active lever presses0.80.81.1-1.00.8-0.90.9-0.9-0.60.9-0.9-1.0-0.90.9-0.91.0-1.0-1.01.0-0.81.01.0-0.50.9-0.9-0.90.9-0.90.9-0.9
Progressive ratio test 2 breakpoint0.40.50.8-0.80.7-0.70.7-0.7-0.50.6-0.6-0.9-0.60.7-0.70.8-0.8-0.80.8-0.60.80.8-0.50.7-0.7-0.70.7-0.70.7-0.6
Progressive ratio test 2 inactive lever presses1.21.44.6-1.42.1-1.21.2-1.2-1.40.7-0.7-1.5-0.91.0-0.91.3-1.3-1.31.3-1.21.41.4-1.60.6-0.6-0.60.6-0.60.6-0.4
Incentive Sensitization - Responses1.11.22.0-1.31.4-1.11.1-1.1-1.20.9-0.9-1.2-1.01.0-1.01.2-1.2-1.21.2-1.11.21.2-1.10.8-0.8-0.80.8-0.80.8-0.8
Incentive Sensitization - Breakpoint1.11.12.0-1.31.4-1.11.1-1.1-1.10.9-0.9-1.2-1.01.0-1.01.2-1.2-1.21.2-1.01.21.2-1.10.8-0.8-0.80.8-0.80.8-0.7
Sum of active levers in priming session hrs 5-60.60.61.20.8-1.10.9-0.90.91.1-0.70.71.00.8-0.80.8-0.90.90.9-0.90.9-0.4-0.40.9-0.60.60.6-0.60.6-0.60.8
Progressive ratio3.03.45.02.1-2.22.1-2.12.11.5-1.91.92.01.8-1.91.7-2.12.12.1-2.12.2-1.8-1.81.7-1.51.51.5-1.51.5-1.50.3
Food seeking constrained by brief footshock1.31.62.9-0.71.3-0.90.9-0.9-1.41.0-1.0-1.4-1.31.3-1.31.3-1.3-1.31.3-1.21.51.5-1.01.3-1.3-1.31.3-1.31.3-1.7
Seeking ratio, punishment vs. effort5.16.29.1-2.53.0-2.62.6-2.6-2.32.4-2.4-2.8-2.52.6-2.42.8-2.8-2.82.8-2.82.62.6-2.42.2-2.2-2.22.2-2.22.2-1.2
Retroperitoneal fat weight0.30.92.41.4-1.31.0-1.01.01.5-1.01.01.10.8-0.90.9-0.90.90.9-0.91.1-0.9-0.91.3-0.50.50.5-0.50.5-0.50.7
Reaction time number correct0.81.23.3-0.91.2-1.01.0-1.0-1.60.9-0.9-1.1-1.01.0-1.21.1-1.1-1.11.1-1.01.11.1-1.11.0-1.0-1.01.0-1.01.0-1.8
Reaction time mean minus median0.20.20.70.5-0.70.4-0.40.4-0.2-0.30.30.70.5-0.50.4-0.40.40.4-0.40.4-0.5-0.50.8-0.50.50.5-0.50.5-0.5-0.1
Reaction time mean minus median AUC0.40.50.90.7-0.90.7-0.70.7-0.0-0.40.40.90.8-0.80.7-0.70.70.7-0.70.6-0.9-0.90.9-0.80.80.8-0.80.8-0.80.1
Reaction time num false alarms0.40.50.7-0.70.6-0.70.7-0.7-0.20.7-0.7-0.8-0.80.9-0.80.5-0.5-0.50.5-0.50.70.7-0.70.9-0.9-0.90.9-0.90.9-0.8
Reaction time num false alarms AUC0.20.30.6-0.30.2-0.30.3-0.30.30.4-0.4-0.6-0.60.6-0.50.2-0.2-0.20.2-0.20.40.4-0.30.8-0.8-0.80.8-0.80.8-0.5
Reaction time trials correct on left0.81.23.3-0.91.2-1.01.0-1.0-1.60.9-0.9-1.1-1.01.0-1.21.1-1.1-1.11.1-1.01.11.1-1.11.0-1.0-1.01.0-1.01.0-1.8
Reaction time trials on left0.91.33.2-1.01.2-1.01.0-1.0-1.60.9-0.9-1.1-1.11.1-1.21.1-1.1-1.11.1-1.01.11.1-1.21.0-1.0-1.01.0-1.01.0-1.8
Reaction time mean0.00.00.1-0.0-0.2-0.10.1-0.10.30.2-0.20.0-0.20.1-0.20.1-0.1-0.10.1-0.00.20.2-0.00.2-0.2-0.20.2-0.20.2-0.0
Reaction time mean AUC0.00.10.1-0.1-0.2-0.10.1-0.10.30.3-0.3-0.1-0.30.2-0.30.2-0.2-0.20.2-0.10.20.20.00.4-0.4-0.40.4-0.40.4-0.2
Median of all reaction times0.10.10.3-0.20.0-0.20.2-0.20.50.3-0.3-0.3-0.40.3-0.40.3-0.3-0.30.3-0.10.50.5-0.30.5-0.5-0.50.5-0.50.5-0.2
Reaction time omissions0.20.31.2-0.60.6-0.80.8-0.8-0.20.5-0.5-0.8-0.60.6-0.60.4-0.4-0.40.4-0.40.60.6-1.10.5-0.5-0.50.5-0.50.5-0.2
Reaction time false alarm rate0.00.10.6-0.1-0.1-0.00.0-0.00.80.1-0.1-0.1-0.20.2-0.1-0.20.20.2-0.20.1-0.0-0.0-0.10.3-0.3-0.30.3-0.30.30.3
Reaction time premature initiation rate1.92.64.31.8-1.61.9-1.91.92.1-1.81.81.41.7-1.51.8-1.51.51.5-1.51.8-1.3-1.31.7-1.41.41.4-1.41.4-1.41.5
Reaction time premature initiations0.60.81.71.2-0.81.3-1.31.31.2-1.21.20.71.0-0.81.0-0.80.80.8-0.81.1-0.6-0.61.1-0.60.60.6-0.60.6-0.60.5
Std. dev. reaction times0.10.10.60.4-0.80.3-0.30.30.3-0.10.10.50.2-0.30.2-0.30.30.3-0.30.3-0.3-0.30.6-0.20.20.2-0.20.2-0.2-0.1
Reaction time trials completed0.91.33.2-1.01.2-1.01.0-1.0-1.60.9-0.9-1.1-1.11.1-1.21.1-1.1-1.11.1-1.01.11.1-1.21.0-1.0-1.01.0-1.01.0-1.8
Reaction time trials AUC1.11.63.9-1.11.3-1.21.2-1.2-1.81.1-1.1-1.3-1.21.2-1.31.3-1.3-1.31.3-1.21.31.3-1.21.1-1.1-1.11.1-1.11.1-2.0
Run reversals in cocaine runway, females2.52.43.8-1.21.9-1.41.4-1.4-1.81.5-1.5-1.7-1.61.7-1.61.7-1.7-1.71.7-1.81.61.6-1.51.4-1.4-1.41.4-1.41.4-0.9
Run reversals in cocaine runway, males1.01.01.60.8-0.30.8-0.80.80.9-1.31.30.61.2-1.01.2-0.90.90.9-0.91.1-0.7-0.70.4-1.21.21.2-1.21.2-1.21.2
Latency to leave start box in cocaine runway0.90.91.70.7-0.70.7-0.70.70.3-0.90.90.91.1-1.11.0-0.90.90.9-0.90.8-1.1-1.10.5-1.31.31.3-1.31.3-1.30.6
Latency to leave start box in cocaine runway, F1.71.93.01.3-0.51.2-1.21.20.7-1.61.61.21.5-1.51.5-1.21.21.2-1.21.2-1.4-1.40.4-1.71.71.7-1.71.7-1.71.6
Latency to leave start box in cocaine runway, M0.10.11.1-0.4-0.4-0.30.3-0.3-0.30.6-0.6-0.1-0.20.2-0.30.0-0.0-0.00.0-0.20.10.10.30.2-0.2-0.20.2-0.20.2-1.0
Std. dev. time between licks in bursts4.25.09.4-2.53.1-2.52.5-2.5-2.92.0-2.0-2.4-2.12.1-2.12.4-2.4-2.42.4-2.52.42.4-2.61.5-1.5-1.51.5-1.51.5-1.5
Total sessions with >9 infusions0.20.21.0-0.30.8-0.50.5-0.5-1.00.1-0.1-0.3-0.0-0.0-0.10.4-0.4-0.40.4-0.40.20.2-0.8-0.40.40.4-0.40.4-0.40.1
Short access day 1 total inactive lever presses5.05.69.8-2.42.5-2.62.6-2.6-3.12.4-2.4-2.4-2.32.3-2.42.7-2.7-2.72.7-2.62.12.1-2.21.8-1.8-1.81.8-1.81.8-2.3
Short access day 10 total inactive lever presses0.40.51.20.10.80.3-0.30.3-0.4-0.70.70.40.7-0.70.7-0.10.10.1-0.10.1-0.2-0.2-0.6-1.11.11.1-1.11.1-1.11.0
Short access day 1 total infusions0.90.92.8-1.21.1-1.21.2-1.2-1.71.0-1.0-0.9-0.80.8-0.91.1-1.1-1.11.1-1.10.60.6-1.00.4-0.4-0.40.4-0.40.4-0.9
Short access day 10 total infusions0.20.20.4-0.30.1-0.40.4-0.4-0.00.4-0.4-0.5-0.50.5-0.50.4-0.4-0.40.4-0.30.60.6-0.00.6-0.6-0.60.6-0.60.6-0.6
Short access total infusions0.91.11.6-0.90.7-1.11.1-1.1-1.01.1-1.1-1.0-1.01.0-1.11.1-1.1-1.11.1-1.11.01.0-0.51.0-1.0-1.01.0-1.01.0-1.2
Short access day 1 locomotion0.00.00.2-0.10.2-0.10.1-0.1-0.50.2-0.2-0.20.00.1-0.10.1-0.1-0.10.1-0.20.10.1-0.1-0.10.10.1-0.10.1-0.1-0.2
Short access day 10 total locomotion0.00.00.30.2-0.40.0-0.00.00.10.2-0.2-0.2-0.10.1-0.10.2-0.2-0.20.20.00.10.10.50.2-0.2-0.20.2-0.20.2-0.5
Short access total locomotion0.00.00.30.0-0.50.0-0.00.0-0.10.3-0.3-0.00.00.0-0.10.0-0.0-0.00.0-0.1-0.2-0.20.60.1-0.1-0.10.1-0.10.1-0.5
One hour access (0.3 mA shock)0.50.61.1-0.70.2-0.60.6-0.6-0.10.8-0.8-0.8-0.80.9-0.80.6-0.6-0.60.6-0.50.70.7-0.11.1-1.1-1.11.1-1.11.1-0.9
Compulsive drug intake0.30.30.9-0.3-0.2-0.40.4-0.4-0.50.8-0.8-0.3-0.70.6-0.60.3-0.3-0.30.3-0.50.10.10.10.8-0.8-0.80.8-0.80.8-0.9
One hour access (shock baseline)0.00.00.2-0.30.3-0.10.1-0.10.3-0.00.0-0.3-0.00.1-0.10.1-0.1-0.10.10.00.40.4-0.00.1-0.1-0.10.1-0.10.10.1
Social response proportion0.20.31.30.8-0.30.6-0.60.61.2-0.70.70.30.4-0.30.5-0.50.50.5-0.50.6-0.4-0.40.2-0.20.20.2-0.20.2-0.20.7
Social responses0.40.50.70.8-0.80.8-0.80.80.6-0.70.70.80.7-0.60.6-0.80.80.8-0.80.8-0.8-0.80.8-0.40.40.4-0.40.4-0.40.1
Social time0.40.61.8-0.71.3-0.80.8-0.8-0.60.1-0.2-0.7-0.70.7-0.70.7-0.7-0.70.7-0.60.80.8-1.00.7-0.7-0.70.7-0.70.7-0.4
Soleus weight3.610.612.03.4-2.93.4-3.43.42.8-3.43.43.43.4-3.43.5-3.23.23.2-3.23.2-3.2-3.22.9-3.23.23.2-3.23.2-3.23.1
Bone: stiffness0.10.20.30.4-0.30.4-0.40.40.5-0.50.50.40.4-0.40.4-0.50.50.5-0.50.5-0.3-0.30.2-0.40.40.4-0.40.4-0.40.4
Tibialis anterior weight0.00.10.30.20.30.1-0.10.1-0.4-0.40.30.10.4-0.30.30.0-0.0-0.00.00.00.10.10.1-0.50.50.5-0.50.5-0.50.3
Time to tail flick, vehicle, before self-admin1.91.92.71.3-1.31.3-1.31.31.6-1.41.41.51.4-1.51.4-1.41.41.4-1.41.3-1.6-1.61.0-1.41.41.4-1.41.4-1.41.6
Time to tail flick, vehicle, after self-admin0.90.92.01.0-0.11.0-1.01.01.0-1.41.41.01.0-1.01.0-0.90.90.9-0.91.1-0.8-0.80.3-0.90.90.9-0.90.9-0.91.1
Time to tail flick, test, before self-admin0.20.21.10.6-1.00.4-0.40.40.90.0-0.00.40.2-0.20.3-0.20.20.2-0.20.5-0.4-0.40.90.0-0.0-0.00.0-0.00.00.3
Time to tail flick, test, after self-admin0.10.10.4-0.20.4-0.00.0-0.00.1-0.20.2-0.00.1-0.10.20.2-0.2-0.20.2-0.00.20.2-0.3-0.20.20.2-0.20.2-0.20.7
Delta time to tail flick, vehicle, before/after SA0.30.31.4-0.61.2-0.50.5-0.5-0.60.2-0.2-0.6-0.40.4-0.50.6-0.6-0.60.6-0.40.80.8-0.90.3-0.3-0.30.3-0.30.3-0.4
Delta time to tail flick, test, before/after SA0.30.20.8-0.80.9-0.50.5-0.5-0.30.3-0.3-0.6-0.40.4-0.40.6-0.6-0.60.6-0.50.60.6-0.70.3-0.3-0.30.3-0.30.30.1
Tibia length6.317.922.14.7-4.24.7-4.74.73.8-4.54.54.74.4-4.54.4-4.14.14.1-4.14.2-4.0-4.04.6-3.93.93.9-3.93.9-3.93.5
Ambulatory time before self-admin0.40.41.4-0.51.1-0.60.6-0.6-0.30.2-0.2-0.8-0.60.6-0.50.7-0.7-0.70.7-0.51.21.2-0.90.5-0.5-0.50.5-0.50.5-0.2
Ambulatory time after self-admin0.40.51.9-0.30.6-0.00.0-0.0-0.80.3-0.3-0.8-0.50.7-0.50.6-0.6-0.60.6-0.11.21.20.10.8-0.8-0.80.8-0.80.8-1.4
Bone: tissue strength2.92.84.51.6-0.91.6-1.61.61.5-1.91.91.41.8-1.71.8-1.61.61.6-1.61.6-1.5-1.50.8-1.91.91.9-1.91.9-1.92.1
Total heroin consumption1.11.32.21.0-0.51.4-1.41.41.1-1.41.40.81.3-1.11.4-0.90.90.9-0.91.3-1.0-1.00.7-1.21.21.2-1.21.2-1.21.5
Bone: trabecular number1.11.73.6-0.90.2-0.90.9-0.9-0.71.5-1.5-1.0-1.41.4-1.41.1-1.1-1.11.1-1.11.11.1-0.01.7-1.7-1.71.7-1.71.7-1.9
Bone: trabecular spacing1.92.55.11.2-0.41.2-1.21.21.1-1.81.81.31.8-1.71.7-1.41.41.4-1.41.4-1.4-1.40.4-2.02.02.0-2.02.0-2.02.3
Bone: trabecular thickness0.10.10.90.3-0.90.3-0.30.30.10.2-0.20.3-0.10.0-0.1-0.10.10.1-0.10.1-0.1-0.10.90.4-0.4-0.40.4-0.40.4-0.8
Bone: trabecular tissue density0.30.40.90.6-0.90.6-0.60.60.9-0.50.50.80.5-0.60.6-0.70.70.7-0.70.7-0.7-0.70.6-0.40.40.4-0.40.4-0.40.7
Water consumed over 24 hours0.10.10.30.10.60.1-0.10.1-0.4-0.40.40.10.3-0.30.3-0.00.00.0-0.0-0.0-0.0-0.0-0.3-0.50.50.5-0.50.5-0.50.4
Number of responses in last shaping day0.40.41.1-1.01.0-0.80.8-0.8-0.90.5-0.5-0.8-0.50.5-0.50.8-0.8-0.80.8-0.70.60.6-0.90.2-0.2-0.20.2-0.20.2-0.3