Hub : Genes

Kl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative TSS NM_031336.2 0.11 0.07 2.7e-03 0.01 0.03 0.04 0.01 1.0e-01 1.4e-02 2.6e-03 6.1e-02
2 BLA alternative TSS XM_039089809.2 0.11 0.07 2.1e-03 0.01 0.03 0.05 0.02 9.9e-02 9.3e-03 1.7e-03 4.2e-02
3 Adipose isoform ratio XM_039089809.2 0.06 0.04 3.0e-06 0.03 0.04 0.04 0.04 1.1e-04 1.9e-05 1.8e-05 1.3e-05
4 BLA gene expression Kl 0.13 0.08 1.0e-03 -0 0.05 0.05 0.03 3.9e-01 9.4e-04 8.6e-04 1.2e-02
5 Brain gene expression Kl 0.04 0.03 3.0e-03 0.02 0.03 0.02 0.02 3.1e-03 1.4e-03 6.4e-03 3.7e-03
6 Adipose gene expression Kl 0.09 0.05 3.0e-09 0.03 0.06 0.05 0.05 1.0e-04 6.1e-07 3.0e-06 5.1e-06
7 NAcc gene expression Kl 0.29 0.11 0.0e+00 0.32 0.32 0.31 0.32 1.9e-49 7.4e-49 9.2e-48 2.0e-49
8 NAcc alternative TSS XM_039089809.2 0.1 0.06 1.9e-13 0.1 0.1 0.08 0.1 1.7e-14 3.6e-14 2.8e-12 3.2e-14
9 NAcc alternative TSS NM_031336.2 0.1 0.06 3.8e-13 0.1 0.09 0.08 0.09 3.0e-14 7.2e-14 5.1e-12 5.8e-14
10 PL gene expression Kl 0.04 0.02 4.2e-04 0.01 0.03 0.03 0.02 1.4e-02 1.8e-04 3.4e-04 1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.34.09.03.0-3.00.82.32.10.22.0-1.91.90.7
Area under the delay curve3.43.95.5-2.12.10.8-1.7-2.3-1.5-2.32.3-2.3-1.8
BMI with tail0.93.010.32.7-2.61.83.20.0-1.20.7-0.60.6-0.6
BMI without tail1.44.211.42.7-2.63.42.4-0.2-2.6-0.30.3-0.3-2.0
Body weight4.619.948.06.5-6.36.95.50.5-5.10.2-0.20.2-3.5
Weight adjusted by age0.50.81.41.0-1.00.10.91.10.31.2-1.01.00.6
Bone surface1.63.08.32.9-2.81.82.41.0-0.91.0-1.01.0-0.3
Bone volume1.42.56.22.5-2.40.72.31.1-0.11.5-1.41.40.4
Breakpoint value in progressive ratio session0.91.11.7-0.40.40.9-0.7-1.0-1.2-1.31.3-1.3-1.3
Number of licking bursts0.71.22.21.5-1.5-0.10.91.50.51.1-1.11.10.7
Context. condit. distance diff. score1.51.86.20.7-0.72.50.0-0.3-2.1-1.01.1-1.1-1.9
Locomotion velocity, session 10.70.81.3-1.21.20.0-1.1-0.8-0.3-1.01.0-1.0-0.5
Locomotion distance, session 10.70.92.4-1.61.5-0.8-1.6-0.40.4-0.60.7-0.70.1
Locomotion velocity, session 20.50.61.1-0.90.90.2-1.0-0.5-0.4-0.80.8-0.8-0.6
Locomotion distance, session 20.81.24.6-1.71.6-0.8-2.10.30.5-0.50.5-0.50.2
Locomotion velocity, session 30.20.30.6-0.10.10.8-0.2-0.3-0.7-0.60.6-0.6-0.7
Locomotion distance, session 30.30.30.80.1-0.2-0.5-0.00.90.70.7-0.60.60.7
Stereotopy head waving bouts, day 31.41.64.52.1-2.11.01.41.2-0.41.1-1.01.00.0
Stereotopy head waving duration, day 30.20.20.30.5-0.5-0.30.60.20.30.5-0.50.50.4
Locomotion velocity, session 72.42.74.1-1.71.70.6-1.3-2.0-1.2-2.01.9-1.9-1.5
Locomotion distance, session 71.41.83.0-1.51.50.6-1.7-0.9-1.0-1.61.5-1.5-1.2
Stereotopy head waving bouts, day 70.20.20.7-0.70.7-0.2-0.8-0.20.0-0.30.4-0.4-0.1
Stereotopy head waving duration, day 70.20.30.8-0.90.9-0.5-0.7-0.40.2-0.30.4-0.40.1
Locomotion velocity, session 80.60.71.1-0.30.40.9-0.3-0.9-1.0-0.81.0-1.0-1.0
Locomotion distance, session 80.71.02.80.2-0.21.7-0.2-0.4-1.5-0.91.0-1.0-1.4
Degree of sensitization distance1.61.62.6-1.61.60.1-1.5-1.2-0.6-1.51.3-1.3-0.9
Degree of sensitization stereotypy0.40.41.0-1.01.0-0.3-0.8-0.60.0-0.60.6-0.6-0.2
Conditioned locomotion0.50.51.00.6-0.6-0.60.60.60.71.0-0.80.80.8
Cocaine response after cond. corrected1.01.25.91.2-1.1-0.42.4-0.60.41.0-0.80.80.6
Cocaine response after cond. not corrected0.40.53.00.6-0.60.11.7-1.0-0.10.2-0.10.1-0.0
Cocaine response before conditioning1.41.73.1-1.11.11.1-1.8-0.6-1.2-1.61.4-1.4-1.4
Saline control response0.81.03.51.2-1.31.5-0.41.9-0.80.4-0.40.4-0.5
Bone: connectivity density2.23.59.33.1-3.01.92.11.8-0.81.3-1.31.3-0.2
Bone: cortical apparent density0.50.71.5-0.90.90.1-0.4-1.2-0.5-1.11.0-1.0-0.6
Bone: cortical area1.42.25.60.5-0.42.40.2-1.1-2.2-1.41.4-1.4-2.0
Bone: cortical porosity0.20.20.40.4-0.4-0.10.20.60.30.5-0.60.60.4
Bone: cortical porosity0.10.10.3-0.40.4-0.2-0.60.20.20.0-0.00.00.1
Bone: cortical thickness1.01.64.50.7-0.62.10.4-0.8-1.9-1.11.0-1.0-1.7
Bone: cortical thickness0.60.82.40.4-0.41.6-0.3-0.0-1.3-0.80.7-0.7-1.2
Bone: cortical tissue density0.40.51.2-0.90.9-0.1-0.4-1.1-0.3-1.00.8-0.8-0.4
Condit. Reinf. active minus inactive responses0.50.61.2-1.11.1-0.1-0.4-1.1-0.1-0.70.8-0.8-0.3
Condit. Reinf. active-inactive response ratio0.60.71.8-0.80.90.3-0.2-1.3-0.6-0.81.0-1.0-0.7
Condit. Reinf. active responses0.50.71.5-1.21.20.0-1.0-0.6-0.2-0.90.8-0.8-0.4
Condit. Reinf. inactive responses0.70.83.2-1.31.3-0.3-1.80.10.1-0.80.6-0.6-0.1
Incentive salience index mean0.40.51.5-1.21.2-0.2-0.8-0.6-0.0-0.70.7-0.7-0.2
Condit. Reinf. lever presses0.30.41.1-1.11.0-0.2-1.0-0.20.1-0.60.5-0.5-0.1
Condit. Reinf. active minus inactive responses1.92.54.6-0.40.42.2-1.1-0.9-2.1-1.71.8-1.8-2.1
Condit. Reinf. active-inactive response ratio1.82.13.1-0.80.81.6-1.3-0.9-1.7-1.71.7-1.7-1.7
Condit. Reinf. active responses2.12.95.4-0.50.52.3-1.3-0.9-2.3-1.81.9-1.9-2.2
Condit. Reinf. inactive responses0.20.20.70.1-0.10.8-0.40.0-0.7-0.50.4-0.4-0.7
Condit. Reinf. lever presses0.50.71.1-0.50.50.7-0.9-0.5-0.8-1.01.1-1.1-0.9
Condit. Reinf. lever reinforcers received2.12.94.6-0.80.82.0-1.6-0.9-2.1-1.92.0-2.0-2.1
Conditioned reinforcement - actives0.71.23.61.6-1.61.90.30.8-1.4-0.00.0-0.0-1.0
Conditioned reinforcement - inactives0.71.01.91.3-1.4-0.30.71.30.51.0-1.01.00.7
Conditioned locomotion0.91.14.01.1-1.12.0-0.10.4-1.5-0.40.4-0.4-1.3
Patch foraging indifference point 0 sec1.83.34.91.4-1.5-1.51.12.11.82.2-2.12.12.0
Patch foraging indifference point AUC0.30.51.20.9-0.90.60.51.1-0.20.6-0.70.70.0
Delay disc. indifference point, 0s delay3.23.58.4-0.50.62.00.4-2.9-2.2-2.02.0-2.0-2.2
Delay disc. indifference point, 16s delay1.11.21.6-1.31.30.4-1.3-1.0-0.7-1.31.3-1.3-0.9
Delay disc. indifference point, 2s delay4.95.510.4-2.62.60.6-1.7-3.2-1.6-2.72.7-2.7-1.9
Delay disc. indifference point, 24s delay1.01.12.5-1.61.6-0.0-1.2-1.0-0.3-1.01.0-1.0-0.5
Delay disc. indifference point, 4s delay2.62.75.3-1.81.80.6-0.9-2.3-1.2-1.91.9-1.9-1.4
Delay disc. indifference point, 8s delay1.31.52.2-1.51.50.4-1.4-1.0-0.8-1.41.4-1.4-1.0
Indifference point function ln k0.10.10.60.0-0.1-0.1-0.80.80.30.3-0.20.20.2
Indifference point function log k0.10.10.60.0-0.1-0.1-0.80.80.30.3-0.20.20.2
Patch foraging total patch changes 0 sec2.34.36.41.5-1.5-1.71.02.52.12.5-2.42.42.3
Patch foraging total patch changes 12 sec1.31.72.41.2-1.2-0.71.21.51.01.5-1.61.61.2
Patch foraging total patch changes 18 sec2.33.45.51.3-1.3-1.21.32.21.82.4-2.32.32.0
Patch foraging total patch changes 24 sec1.11.85.60.3-0.3-1.0-0.52.41.51.5-1.51.51.5
Patch foraging total patch changes 6 sec2.13.25.11.4-1.5-1.01.22.31.62.2-2.22.21.8
Patch foraging time to switch 0 sec0.81.69.3-0.80.9-0.41.5-3.0-0.3-0.80.9-0.9-0.4
Patch foraging water rate 0 sec1.53.212.41.8-1.80.4-0.23.50.72.0-1.91.91.0
Patch foraging water rate 12 sec0.20.42.10.2-0.20.2-1.01.50.20.3-0.50.50.2
Patch foraging water rate 18 sec0.71.14.8-1.11.10.5-2.20.2-0.5-1.01.0-1.0-0.7
Patch foraging water rate 24 sec0.60.82.81.0-1.01.3-0.21.7-0.50.6-0.50.5-0.3
Patch foraging water rate 6 sec0.30.42.10.6-0.60.3-0.71.40.20.5-0.50.50.2
Seeking ratio, delayed vs. immediate footshock1.82.25.60.3-0.4-2.40.30.92.21.5-1.51.52.1
Distance traveled before self-admin0.81.02.5-1.61.60.2-0.7-1.1-0.3-0.91.0-1.0-0.5
Distance traveled after self-admin0.40.51.6-1.11.10.2-1.30.0-0.2-0.60.6-0.6-0.3
Extensor digitorum longus weight1.66.220.63.2-3.14.51.70.7-3.4-0.30.4-0.4-2.6
Bone: elastic displacement0.10.10.30.6-0.60.30.30.5-0.10.3-0.30.30.0
Bone: elastic work1.11.53.92.0-1.91.61.21.1-0.90.5-0.60.6-0.5
Bone: endosteal estimation0.71.63.31.7-1.70.30.91.80.31.4-1.41.40.6
Bone: endosteal perimeter0.20.41.10.7-0.71.1-0.20.8-0.70.2-0.10.1-0.5
Epididymis fat weight0.00.10.2-0.30.30.2-0.5-0.0-0.3-0.30.3-0.3-0.3
Delta time in closed arm before/after self-admin1.00.91.7-0.20.21.1-0.1-0.8-1.3-1.01.1-1.1-1.3
Delta time in open arm before/after self-admin1.21.23.8-1.21.1-2.0-1.5-0.31.40.0-0.10.11.1
Diff in mean of infusions in LGA sessions0.00.10.10.3-0.30.2-0.40.3-0.2-0.00.1-0.1-0.2
Delay discount exponential model param4.14.56.22.5-2.5-0.72.02.41.42.4-2.42.41.8
Extinction: sum of active levers before priming0.40.50.8-0.90.9-0.1-0.8-0.7-0.2-0.80.7-0.7-0.4
Active lever presses in extinction session 60.10.10.20.1-0.10.10.20.40.10.3-0.30.30.1
Bone: final force0.91.54.91.4-1.32.20.8-0.0-1.8-0.30.4-0.4-1.4
Bone: final moment0.71.13.61.3-1.21.90.80.1-1.5-0.20.2-0.2-1.2
Food consumed during 24 hour testing period1.21.62.71.2-1.2-0.61.11.41.01.6-1.51.51.1
Glucose1.01.53.5-1.91.9-0.8-1.3-1.50.0-1.01.1-1.1-0.4
Heart weight0.50.71.5-0.50.51.1-1.20.1-1.0-0.80.8-0.8-1.0
Delay discount hyperbolic model param3.94.35.92.4-2.4-0.71.92.41.42.3-2.32.31.8
Intermittent access intake day 1-15 change0.71.42.91.5-1.50.10.61.70.51.4-1.41.40.7
Intermittent access intake escalation0.71.42.51.5-1.50.00.81.60.51.3-1.31.30.7
Intermittent access intake escalation 20.50.61.10.3-0.3-0.7-0.01.10.91.0-1.01.00.9
Intermitt. access day 1 inactive lever presses0.31.22.21.5-1.5-0.40.81.20.71.2-1.21.20.9
Intermitt. access day 15 inactive lever presses0.71.54.61.3-1.3-1.02.1-0.20.91.1-1.11.11.1
Intermitt. access escalation Index0.40.61.9-0.90.90.2-1.4-0.3-0.3-0.70.7-0.7-0.5
Intermittent access day 1 total infusions0.71.22.8-1.21.20.3-1.7-0.8-0.6-1.21.2-1.2-0.8
Intermittent access day 15 total infusions0.10.20.90.0-0.00.3-1.00.3-0.3-0.30.3-0.3-0.4
Intermittent access terminal intake (last 3 days)0.10.10.9-0.30.20.1-0.9-0.0-0.2-0.30.3-0.3-0.3
Intermittent access total infusions0.70.91.3-0.80.80.5-1.0-0.9-0.8-1.11.1-1.1-0.9
Intermittent access day 1 locomotion1.11.42.4-1.11.10.3-1.5-1.2-0.7-1.41.4-1.4-1.0
Intermittent access day 15 total locomotion0.20.41.90.1-0.10.8-1.40.4-0.7-0.50.5-0.5-0.7
Intermittent access total locomotion0.91.02.4-0.80.90.5-1.6-0.7-0.8-1.21.2-1.2-0.9
Intermittent access standard deviation0.92.03.51.6-1.6-0.81.90.81.01.6-1.61.61.3
Left kidney weight3.215.039.46.3-6.15.14.72.1-3.21.4-1.61.6-1.8
Right kidney weight2.812.632.45.7-5.54.64.71.6-3.01.3-1.31.3-1.7
Cocaine induced anxiety0.60.81.3-0.70.70.4-0.6-1.1-0.8-1.11.1-1.1-0.9
Post-drug Anxiety3.23.410.5-1.71.8-0.1-0.7-3.2-0.9-2.22.2-2.2-1.3
Baseline Anxiety1.01.15.3-1.11.2-0.80.1-2.30.1-0.90.9-0.9-0.2
Tail length2.59.833.23.9-3.75.82.20.6-4.3-0.60.6-0.6-3.3
Length with tail5.222.665.46.7-6.58.14.51.3-5.8-0.10.1-0.1-4.2
Length without tail4.013.034.15.8-5.74.54.81.9-2.71.5-1.61.6-1.4
Times rat made contact with spout0.30.41.30.5-0.51.20.0-0.0-1.0-0.40.4-0.4-0.9
Lifetime Intake0.50.61.0-0.70.70.2-0.8-1.0-0.5-1.01.0-1.0-0.7
Liver weight, left4.27.013.73.7-3.70.32.63.00.82.7-2.82.81.4
Liver weight, right1.42.56.92.6-2.61.52.30.8-0.70.8-1.01.0-0.2
Locomotor activity1.32.05.80.0-0.02.4-1.50.4-2.0-1.11.2-1.2-1.9
Locomotor testing distance0.20.41.60.8-0.80.7-0.21.3-0.20.5-0.40.4-0.1
Locomotor testing rearing0.50.91.60.5-0.6-0.90.31.31.11.2-1.11.11.1
Locomotion in novel chamber0.30.41.50.8-0.81.2-0.10.9-0.60.1-0.20.2-0.4
Locomotion in novel chamber post-restriction0.60.93.50.5-0.51.9-0.70.7-1.4-0.50.6-0.6-1.2
Fecal boli incidents, locomotor time 10.50.72.90.4-0.41.7-0.10.2-1.3-0.60.6-0.6-1.1
Change in fecal boli incidents, locomotor task0.20.20.30.4-0.3-0.50.5-0.30.40.3-0.40.40.5
Time >=10cm from walls, locomotor time 11.51.63.8-1.71.7-0.5-0.8-1.9-0.3-1.41.3-1.3-0.6
Bouts of movement, locomotor time 10.40.41.20.9-0.91.10.60.6-0.8-0.10.0-0.0-0.6
Total resting periods, locomotor time 10.40.41.30.8-0.81.20.50.4-0.9-0.30.2-0.2-0.7
Rest time, locomotor task time 10.60.71.91.2-1.21.41.00.0-1.0-0.20.1-0.1-0.7
Distance moved, locomotor task time 10.50.72.0-1.41.4-0.2-1.3-0.5-0.1-0.60.7-0.7-0.3
Vertical activity count, locomotor time 10.20.41.7-0.80.70.3-1.30.2-0.4-0.50.5-0.5-0.5
Time >=10cm from walls, locomotor time 20.91.33.20.1-0.11.10.7-1.8-1.4-1.11.2-1.2-1.4
Bouts of movement, locomotor time 20.20.31.00.9-0.81.00.10.5-0.70.0-0.00.0-0.5
Total resting periods, locomotor time 20.20.31.01.0-1.00.80.20.6-0.50.2-0.30.3-0.3
Rest time, locomotor task time 20.00.10.2-0.30.3-0.4-0.4-0.20.2-0.20.1-0.10.2
Distance moved, locomotor task time 20.10.10.30.4-0.40.10.50.50.10.4-0.40.40.1
Vertical activity count, locomotor time 20.60.81.91.4-1.41.00.91.2-0.50.6-0.50.5-0.2
Light reinforcement 11.12.83.9-2.02.00.0-2.0-1.8-0.8-2.01.8-1.8-1.2
Light reinforcement 20.10.10.50.1-0.1-0.7-0.10.20.60.3-0.30.30.5
Bone: marrow area0.81.73.51.7-1.70.20.81.90.41.4-1.41.40.7
Bone: maximum diameter0.40.82.11.4-1.31.41.00.3-1.00.1-0.10.1-0.7
Bone: maximum force0.61.13.61.3-1.31.90.60.4-1.4-0.10.2-0.2-1.1
Bone: maximum moment0.50.82.61.3-1.21.60.50.5-1.10.0-0.00.0-0.8
Mean time between licks in bursts0.30.82.2-1.21.1-1.5-0.90.21.20.3-0.40.40.9
Mean num. licks in bursts0.20.40.7-0.60.60.4-0.3-0.8-0.6-0.70.6-0.6-0.7
Cd content in liver1.11.34.3-1.31.30.4-2.10.0-0.6-1.11.2-1.2-0.8
Co content in liver2.93.45.81.3-1.4-1.01.12.41.62.3-2.42.41.8
Cu content in liver0.10.10.3-0.20.2-0.6-0.30.40.50.4-0.30.30.4
Fe content in liver0.50.61.2-0.30.31.0-1.0-0.1-1.1-0.80.8-0.8-1.1
K content in liver0.20.10.50.0-0.00.20.4-0.7-0.4-0.50.4-0.4-0.3
Mg content in liver0.30.31.30.9-0.90.51.1-0.0-0.30.2-0.30.3-0.1
Mn content in liver0.30.30.50.1-0.1-0.70.40.20.70.6-0.60.60.7
Na content in liver0.50.50.90.9-0.91.00.7-0.2-0.8-0.60.4-0.4-0.6
Rb content in liver1.11.33.9-2.01.9-1.3-1.2-0.80.8-0.50.5-0.50.4
Se content in liver2.02.34.5-0.10.11.70.4-2.1-2.0-1.71.7-1.7-1.9
Sr content in liver1.11.01.51.1-1.1-0.30.81.20.61.2-1.21.20.8
Zn content in liver2.62.96.42.5-2.50.71.92.00.11.6-1.71.70.6
Bone: minimum diameter0.00.00.1-0.10.1-0.2-0.30.10.1-0.0-0.00.00.1
Time in familiar zone, hab. session 11.71.72.80.8-0.8-1.41.40.71.41.7-1.51.51.5
Time in novel zone, hab. session 10.80.81.4-0.20.21.2-0.4-0.6-1.1-1.10.9-0.9-1.1
Total zone transitions, hab. session 11.31.94.6-2.12.1-0.3-2.1-0.8-0.1-1.11.3-1.3-0.5
Total locomotion distance, hab. session 10.91.22.2-1.51.50.0-1.3-1.1-0.4-1.21.2-1.2-0.7
Locomotion velocity, hab. session 11.52.14.4-2.12.1-0.3-1.9-1.3-0.3-1.41.5-1.5-0.7
Time in familiar zone, hab. session 20.10.20.80.3-0.3-0.20.9-0.50.10.4-0.20.20.1
Time in novel zone, hab. session 20.40.41.6-1.00.9-0.1-1.30.0-0.0-0.60.5-0.5-0.2
Total zone transitions, hab. session 20.10.20.4-0.10.10.6-0.50.1-0.5-0.40.4-0.4-0.5
Total locomotion distance, hab. session 20.30.30.9-0.80.80.1-1.0-0.2-0.2-0.60.6-0.6-0.3
Locomotion velocity, hab. session 20.20.31.0-0.80.80.1-1.0-0.1-0.1-0.50.5-0.5-0.3
Novel to familiar place preference ratio0.10.20.4-0.40.40.1-0.6-0.2-0.2-0.50.4-0.4-0.3
Novelty place preference0.20.20.6-0.70.7-0.1-0.8-0.2-0.1-0.50.5-0.5-0.2
Time in novel zone, NPP test0.20.20.4-0.50.50.0-0.6-0.2-0.2-0.50.4-0.4-0.3
Total zone transitions, NPP test0.20.40.6-0.50.50.6-0.8-0.2-0.6-0.60.7-0.7-0.6
Total locomotion distance, NPP test1.31.82.4-1.31.30.9-1.3-1.2-1.1-1.51.6-1.6-1.3
Locomotion velocity, NPP test1.31.82.7-1.41.41.0-1.6-0.9-1.1-1.51.5-1.5-1.3
Intraocular pressure0.50.71.91.4-1.41.10.71.1-0.50.1-0.30.3-0.3
Delta distance traveled before/after self-admin0.60.62.00.6-0.7-0.4-0.51.40.60.8-0.90.90.7
Delta ambulatory time before/after self-admin0.50.61.20.1-0.1-1.0-0.81.11.00.7-0.80.80.9
Parametrial fat weight0.20.52.60.7-0.70.11.6-1.0-0.2-0.1-0.00.0-0.1
Pavlov. Cond. lever latency1.21.64.42.1-2.11.01.51.0-0.40.9-0.90.90.0
Pavlov. Cond. magazine entry latency0.40.51.0-0.20.20.9-0.5-0.3-1.0-0.70.7-0.7-1.0
Pavlov. Cond. change in total contacts1.71.83.4-1.41.40.4-0.8-1.8-0.9-1.71.5-1.5-1.1
Pavlov. Cond. index score0.50.60.9-0.90.90.3-0.7-0.9-0.5-0.90.9-0.9-0.7
Pavlov. Cond. latency score0.81.01.6-1.31.30.1-1.0-1.1-0.5-1.11.1-1.1-0.7
Pavlov. Cond. lever contacts1.11.33.5-1.91.8-0.8-1.2-1.20.2-1.00.9-0.9-0.2
Pavlov. Cond. magazine entry number0.60.71.30.4-0.4-1.00.80.51.11.0-0.90.91.1
Pavlov. Cond. intertrial magazine entries0.40.51.4-0.80.7-1.2-0.70.41.10.2-0.30.30.9
Pavlov. Cond. lever-magazine prob. diff.0.40.50.8-0.80.80.2-0.5-0.9-0.5-0.80.8-0.8-0.6
Pavlov. Cond. response bias0.50.60.9-0.60.60.7-0.7-0.6-0.8-0.90.8-0.8-0.9
Pavlov. Cond. lever latency1.41.92.91.4-1.4-0.61.71.11.01.6-1.71.71.2
Pavlov. Cond. magazine entry latency3.03.65.6-2.32.40.2-1.9-2.1-0.9-2.22.1-2.1-1.3
Pavlov. Cond. change in total contacts1.01.63.8-1.51.50.4-2.0-0.6-0.8-1.41.5-1.5-1.0
Pavlov. Cond. index score2.33.05.3-2.22.20.3-2.3-1.4-0.9-1.92.0-2.0-1.2
Pavlov. Cond. latency score2.12.84.3-2.12.10.3-2.1-1.5-0.9-1.91.9-1.9-1.2
Pavlov. Cond. lever contacts1.82.53.6-1.71.70.7-1.9-1.3-1.1-1.81.9-1.9-1.4
Pavlov. Cond. magazine entry number2.22.75.12.3-2.30.12.11.50.61.8-1.81.81.0
Pavlov. Cond. intertrial magazine entries0.20.30.70.9-0.90.60.20.8-0.30.5-0.40.4-0.1
Pavlov. Cond. lever-magazine prob. diff.2.63.45.9-2.32.30.3-2.4-1.5-0.9-2.02.1-2.1-1.3
Pavlov. Cond. response bias3.04.16.9-2.42.40.6-2.6-1.6-1.2-2.22.3-2.3-1.6
Time in closed arm before self-admin0.70.92.21.4-1.51.00.31.4-0.40.6-0.70.7-0.1
Time in closed arm after self-admin0.80.82.71.0-1.11.60.00.8-1.2-0.20.3-0.3-1.0
Time in open arm before self-admin1.01.11.7-1.21.30.8-0.7-0.8-1.0-1.01.1-1.1-1.0
Time in open arm after self-admin0.60.61.4-1.21.2-1.1-0.9-0.70.7-0.30.3-0.30.5
Bone: periosteal estimation0.40.92.81.4-1.31.70.60.5-1.20.0-0.00.0-0.9
Bone: periosteal perimeter0.71.12.5-0.10.11.6-0.8-0.4-1.5-1.11.1-1.1-1.4
Bone: post-yield work0.10.10.20.3-0.30.3-0.10.5-0.10.3-0.20.2-0.1
Progressive ratio test 1 active lever presses0.50.62.40.9-0.81.50.1-0.0-1.1-0.40.4-0.4-1.0
Progressive ratio test 1 breakpoint0.50.62.40.8-0.81.50.1-0.1-1.2-0.40.4-0.4-1.0
Progressive ratio test 1 inactive lever presses0.71.12.81.7-1.70.30.41.40.10.9-0.90.90.4
Progressive ratio test 2 active lever presses0.30.41.60.5-0.51.3-0.10.6-0.8-0.10.1-0.1-0.7
Progressive ratio test 2 breakpoint0.30.31.50.5-0.51.2-0.20.6-0.8-0.20.2-0.2-0.7
Progressive ratio test 2 inactive lever presses1.32.14.72.2-2.21.01.22.0-0.11.3-1.31.30.2
Incentive Sensitization - Responses0.00.00.1-0.30.2-0.2-0.20.40.20.1-0.10.10.2
Incentive Sensitization - Breakpoint0.10.10.2-0.30.3-0.2-0.30.40.30.1-0.10.10.2
Sum of active levers in priming session hrs 5-60.30.31.00.7-0.70.01.0-0.8-0.3-0.20.3-0.3-0.2
Progressive ratio0.10.10.5-0.10.1-0.70.2-0.50.50.1-0.10.10.4
Food seeking constrained by brief footshock3.23.96.71.1-1.2-2.60.81.62.62.1-2.12.12.5
Seeking ratio, punishment vs. effort0.40.61.31.0-1.0-0.00.51.10.30.8-0.80.80.4
Retroperitoneal fat weight0.21.04.5-0.40.50.30.8-2.1-0.8-1.01.0-1.0-0.8
Reaction time number correct0.61.23.90.9-1.0-0.2-0.22.00.71.3-1.31.30.9
Reaction time mean minus median3.17.710.9-2.22.32.2-2.6-2.5-2.8-3.33.3-3.3-3.0
Reaction time mean minus median AUC1.53.87.5-2.32.30.8-2.7-1.3-1.3-2.22.1-2.1-1.7
Reaction time num false alarms1.41.94.3-1.51.50.6-2.1-0.8-1.0-1.41.6-1.6-1.3
Reaction time num false alarms AUC0.71.12.6-1.11.10.6-1.6-0.6-0.8-1.11.2-1.2-1.0
Reaction time trials correct on left0.61.23.90.9-1.0-0.2-0.22.00.71.3-1.31.30.9
Reaction time trials on left0.61.13.60.9-0.9-0.1-0.21.90.61.2-1.21.20.8
Reaction time mean3.25.08.1-2.82.9-0.0-2.3-2.7-0.9-2.42.5-2.5-1.4
Reaction time mean AUC3.04.88.4-2.92.9-0.2-2.4-2.5-0.8-2.32.4-2.4-1.3
Median of all reaction times2.23.26.6-2.62.6-0.9-1.7-2.3-0.1-1.71.8-1.8-0.5
Reaction time omissions1.42.13.1-1.61.60.3-1.4-1.6-0.9-1.71.8-1.8-1.2
Reaction time false alarm rate1.62.23.3-1.41.40.7-1.4-1.5-1.2-1.71.8-1.8-1.5
Reaction time premature initiation rate1.01.51.9-1.11.11.0-1.3-1.0-1.1-1.41.3-1.3-1.2
Reaction time premature initiations0.30.51.8-0.60.70.8-1.3-0.1-0.7-0.60.6-0.6-0.7
Std. dev. reaction times3.25.88.3-2.32.41.2-2.4-2.5-1.9-2.92.9-2.9-2.3
Reaction time trials completed0.61.13.60.9-0.9-0.1-0.21.90.61.2-1.21.20.8
Reaction time trials AUC0.51.03.50.7-0.7-0.3-0.41.90.71.2-1.11.10.8
Run reversals in cocaine runway, females0.30.31.3-0.30.3-1.1-0.2-0.10.90.3-0.30.30.8
Run reversals in cocaine runway, males0.40.41.60.3-0.3-0.6-0.81.20.60.4-0.40.40.5
Latency to leave start box in cocaine runway0.10.10.5-0.30.30.3-0.1-0.7-0.2-0.30.3-0.3-0.2
Latency to leave start box in cocaine runway, F0.20.31.40.6-0.60.31.2-0.4-0.10.3-0.30.30.0
Latency to leave start box in cocaine runway, M0.50.52.0-0.90.90.2-1.4-0.3-0.1-0.60.5-0.5-0.3
Std. dev. time between licks in bursts0.30.31.1-0.40.30.6-1.00.2-0.5-0.60.6-0.6-0.6
Total sessions with >9 infusions0.10.10.20.3-0.3-0.40.5-0.50.20.1-0.10.10.2
Short access day 1 total inactive lever presses1.01.32.11.4-1.4-0.51.50.70.71.2-1.21.20.9
Short access day 10 total inactive lever presses2.45.811.63.1-3.1-0.43.41.71.12.6-2.62.61.6
Short access day 1 total infusions0.30.41.50.0-0.0-1.20.4-0.40.90.4-0.40.40.8
Short access day 10 total infusions0.10.10.3-0.50.4-0.6-0.2-0.30.4-0.10.1-0.10.2
Short access total infusions0.20.21.3-0.30.3-0.70.1-1.10.2-0.30.3-0.30.1
Short access day 1 locomotion1.31.62.5-1.01.00.6-1.3-1.4-1.1-1.61.6-1.6-1.3
Short access day 10 total locomotion0.30.60.91.0-1.0-0.40.50.70.70.9-0.90.90.8
Short access total locomotion0.40.41.3-0.50.5-0.2-0.7-1.2-0.2-0.80.8-0.8-0.4
One hour access (0.3 mA shock)0.70.84.30.7-0.80.4-1.02.10.10.6-0.60.60.2
Compulsive drug intake0.70.92.5-1.21.1-1.6-0.90.21.30.2-0.20.21.0
One hour access (shock baseline)0.61.03.00.7-0.71.7-0.70.4-1.5-0.60.6-0.6-1.3
Social response proportion3.43.911.31.0-1.03.40.2-1.0-3.0-1.61.6-1.6-2.7
Social responses0.81.13.70.6-0.61.9-0.60.3-1.5-0.80.6-0.6-1.4
Social time1.92.66.0-2.52.4-0.6-2.3-1.2-0.1-1.51.5-1.5-0.5
Soleus weight0.41.23.11.8-1.71.60.81.1-0.90.4-0.40.4-0.5
Bone: stiffness0.71.22.5-0.20.21.6-0.9-0.4-1.5-1.11.2-1.2-1.5
Tibialis anterior weight2.37.925.43.3-3.25.02.10.0-4.0-0.80.9-0.9-3.1
Time to tail flick, vehicle, before self-admin2.12.14.7-1.51.50.4-0.8-2.2-1.0-1.81.7-1.7-1.2
Time to tail flick, vehicle, after self-admin0.30.40.6-0.60.70.3-0.4-0.4-0.6-0.70.8-0.8-0.7
Time to tail flick, test, before self-admin0.40.41.01.0-1.01.00.60.7-0.50.3-0.40.4-0.3
Time to tail flick, test, after self-admin0.30.31.1-0.40.50.2-0.2-1.1-0.4-0.60.6-0.6-0.5
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.10.1-0.5-0.40.90.40.4-0.30.30.4
Delta time to tail flick, test, before/after SA0.30.31.1-0.60.6-1.0-0.1-0.50.70.00.1-0.10.5
Tibia length1.74.812.43.5-3.42.83.20.3-2.00.6-0.50.5-1.2
Ambulatory time before self-admin0.71.01.8-1.31.40.7-0.6-0.9-0.7-1.01.1-1.1-0.8
Ambulatory time after self-admin0.50.51.6-1.31.2-0.1-1.20.00.1-0.50.5-0.5-0.1
Bone: tissue strength2.22.23.31.2-1.2-1.11.31.41.51.7-1.81.81.6
Total heroin consumption2.32.75.1-2.32.2-0.8-2.0-1.6-0.2-1.71.8-1.8-0.7
Bone: trabecular number1.32.25.72.4-2.31.41.91.2-0.61.1-1.01.0-0.1
Bone: trabecular spacing0.81.13.3-1.51.5-1.8-0.9-0.51.3-0.10.1-0.10.9
Bone: trabecular thickness1.31.64.12.0-2.01.61.50.8-1.00.7-0.60.6-0.6
Bone: trabecular tissue density5.27.711.6-1.92.02.3-1.7-3.0-2.9-3.33.4-3.4-3.1
Water consumed over 24 hours1.21.64.32.1-2.10.91.21.5-0.21.1-1.01.00.1
Number of responses in last shaping day0.00.00.2-0.10.1-0.4-0.0-0.40.1-0.10.1-0.10.1