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chr10:92,588,108-96,071,622

Trait: Body weight

Best TWAS P=1.11e-10 · Best GWAS P=1.51e-10 conditioned to NaN

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Fam20a	alternative polyA	NM_001012237.2	0.32	42	0.3	9.8e-34	5.56	2.77e-08	0.59	FALSE
Adipose	Fam20a	alternative polyA	XM_039086178.1	0.33	41	0.3	7.2e-34	-5.56	2.71e-08	0.59	FALSE
Adipose	Fam20a	alternative polyA	NM_001012237.2	0.36	60	0.3	6.9e-34	5.47	4.55e-08	0.58	FALSE
Adipose	Fam20a	alternative polyA	XM_039086178.1	0.37	61	0.31	2.5e-34	-5.51	3.62e-08	0.58	FALSE
Adipose	Abca6	gene expression	Abca6	0.24	188	0.31	9.1e-35	5.33	9.71e-08	0.86	FALSE
Adipose	Abca9	gene expression	Abca9	0.61	171	0.57	1.1e-76	5.61	2.00e-08	0.86	FALSE
Adipose	LOC100912202	gene expression	LOC100912202	0.15	1	0.08	5.3e-09	-5.64	1.66e-08	0.43	FALSE
Adipose	Prkar1a	gene expression	Prkar1a	0.09	1	0.09	5.6e-10	-5.24	1.61e-07	0.08	FALSE
Adipose	Fam20a	isoform ratio	NM_001012237.2	0.15	2982	0.15	2.6e-16	5.49	3.98e-08	0.6	FALSE
Adipose	Arsg	intron excision ratio	chr10_94518127_94528234	0.09	1	0.06	2.5e-07	5.67	1.46e-08	0.34	FALSE
Adipose	Cep112	intron excision ratio	chr10_93731914_93738578	0.05	1	0.04	3.5e-05	-5.58	2.41e-08	0.05	FALSE
Adipose	Cep112	mRNA stability	Cep112	0.1	5	0.06	5.1e-07	5.24	1.58e-07	0.65	FALSE
Adipose	Prkar1a	mRNA stability	Prkar1a	0.08	2937	0.06	2.2e-07	5.51	3.60e-08	0.66	FALSE
BLA	Abca9	alternative TSS	XM_039087440.1	0.06	41	0.04	2.5e-03	-5.5	3.76e-08	0.48	FALSE
BLA	Abca9	alternative TSS	XM_039087443.1	0.08	1	0.05	1.3e-03	-5.9	3.65e-09	0.07	FALSE
BLA	Abca6	gene expression	Abca6	0.15	1	0.13	1.3e-07	5.82	5.99e-09	0.71	FALSE
BLA	Amz2	gene expression	Amz2	0.26	1	0.29	5.7e-16	-5.87	4.42e-09	0.63	FALSE
BLA	Axin2	gene expression	Axin2	0.09	18	0.05	1.3e-03	6.09	1.13e-09	0.55	FALSE
BLA	Arsg	intron excision ratio	chr10_94460446_94461943	0.2	19	0.27	1.0e-14	5.88	4.01e-09	0.56	FALSE
Brain	Arsg	alternative polyA	XM_008768369.2	0.07	2839	0.06	1.1e-06	6.04	1.58e-09	0.55	FALSE
Brain	Arsg	alternative polyA	XM_039086177.1	0.06	2839	0.05	2.4e-05	-5.58	2.46e-08	0.34	FALSE
Brain	Arsg	alternative TSS	XM_006247602.4	0.03	1	0.02	6.2e-03	-6	2.01e-09	0.06	FALSE
Brain	Arsg	alternative TSS	XM_008768369.2	0.15	22	0.14	8.2e-13	-6.08	1.22e-09	0.8	FALSE
Brain	Arsg	alternative TSS	XM_006247602.4	0.07	2839	0.06	5.9e-06	5.82	5.82e-09	0.64	FALSE
Brain	Arsg	alternative TSS	XM_008768369.2	0.16	28	0.17	4.8e-16	-6.1	1.03e-09	0.73	FALSE
Brain	Map2k6	alternative TSS	NM_053703.3	0.19	19	0.2	5.4e-18	6.37	1.83e-10	0.85	FALSE
Brain	Map2k6	alternative TSS	XM_039085033.1	0.21	29	0.22	8.6e-20	-5.87	4.40e-09	0.84	TRUE
Brain	Slc16a6	alternative TSS	XM_039086231.1	0.03	1	0.04	5.6e-05	5.98	2.20e-09	0.23	FALSE
Brain	Wipi1	alternative TSS	XM_008768367.3	0.04	2923	0.01	1.3e-02	-5.56	2.76e-08	0.45	FALSE
Brain	Abca9	gene expression	Abca9	0.71	20	0.66	3.1e-82	-5.36	8.36e-08	0.77	FALSE
Brain	Amz2	gene expression	Amz2	0.18	2782	0.19	8.7e-18	5.8	6.61e-09	0.48	FALSE
Brain	Cep112	gene expression	Cep112	0.21	388	0.21	7.1e-19	5.61	2.03e-08	0.55	FALSE
Brain	LOC102550112	gene expression	LOC102550112	0.02	1	0.01	1.5e-02	-5.87	4.34e-09	0.03	FALSE
Brain	LOC120095201	gene expression	LOC120095201	0.12	2274	0.13	6.6e-12	5.48	4.19e-08	0.11	FALSE
Brain	Prkar1a	gene expression	Prkar1a	0.14	76	0.12	7.0e-11	-5.2	1.97e-07	0.53	FALSE
Brain	Prkca	gene expression	Prkca	0.15	146	0.12	7.5e-11	5.46	4.64e-08	0.62	FALSE
Brain	RGD1565459	gene expression	RGD1565459	0.14	2303	0.14	3.4e-13	5.37	7.92e-08	0.64	FALSE
Brain	Rgs9	gene expression	Rgs9	0.05	2499	0.05	3.8e-05	-5.78	7.46e-09	0.6	FALSE
Brain	Slc16a6	gene expression	Slc16a6	0.39	176	0.43	9.6e-44	-5.88	4.21e-09	0.48	FALSE
Brain	Arsg	isoform ratio	XR_005489859.1	0.1	2839	0.05	2.2e-05	-5.67	1.42e-08	0.47	FALSE
Brain	Cep112	isoform ratio	XR_005489759.1	0.03	1	0.02	4.1e-03	-5.68	1.34e-08	0.03	FALSE
Brain	Arsg	intron excision ratio	chr10_94460446_94461943	0.34	186	0.42	2.6e-42	-5.81	6.43e-09	0.47	FALSE
Brain	Map2k6	intron excision ratio	chr10_95373426_95448972	0.18	2818	0.15	5.7e-14	6.35	2.14e-10	0.78	FALSE
Brain	Map2k6	intron excision ratio	chr10_95447514_95448972	0.14	2818	0.14	3.4e-13	-6.4	1.53e-10	0.8	TRUE
Brain	Rgs9	mRNA stability	Rgs9	0.08	1	0.06	4.1e-06	5.76	8.37e-09	0.34	FALSE
Eye	Arsg	isoform ratio	XR_005489859.1	0.3	37	0.14	3.4e-03	5.59	2.23e-08	0.28	FALSE
Eye	Wipi1	mRNA stability	Wipi1	0.45	41	0.15	2.7e-03	5.91	3.34e-09	0.51	FALSE
IL	Abca9	gene expression	Abca9	0.5	1	0.34	6.0e-09	6.03	1.66e-09	0.84	FALSE
IL	Amz2	gene expression	Amz2	0.23	2782	0.11	1.7e-03	5.71	1.11e-08	0.54	FALSE
IL	Axin2	gene expression	Axin2	0.29	2034	0.16	1.1e-04	-5.18	2.25e-07	0.47	FALSE
IL	LOC120095201	gene expression	LOC120095201	0.19	8	0.07	1.0e-02	6.32	2.66e-10	0.33	FALSE
IL	Rgs9	gene expression	Rgs9	0.2	1	0.03	6.7e-02	6.01	1.82e-09	0.05	FALSE
IL	Wipi1	isoform ratio	XM_008768367.3	0.16	1	0.06	1.3e-02	5.66	1.52e-08	0.05	FALSE
LHb	Abca9	gene expression	Abca9	0.39	1	0.34	8.4e-09	5.35	8.89e-08	0.11	FALSE
LHb	Amz2	gene expression	Amz2	0.17	1	0.13	6.0e-04	-5.81	6.30e-09	0.06	FALSE
LHb	Cep112	gene expression	Cep112	0.41	1	0.31	3.2e-08	6.22	4.90e-10	0.61	FALSE
LHb	LOC120095201	gene expression	LOC120095201	0.19	2274	0.03	7.5e-02	6.07	1.29e-09	0.31	FALSE
LHb	Slc16a6	gene expression	Slc16a6	0.3	24	0.13	4.5e-04	5.46	4.70e-08	0.5	FALSE
Liver	Abca6	alternative TSS	XM_006247656.4	0.18	6	0.15	2.1e-16	5.61	1.99e-08	0.8	FALSE
Liver	Abca6	alternative TSS	XM_006247656.4	0.22	3097	0.21	7.4e-23	6.22	4.89e-10	0.84	FALSE
Liver	Apoh	gene expression	Apoh	0.17	2126	0.13	2.1e-14	5.98	2.25e-09	0.7	FALSE
Liver	Cep112	gene expression	Cep112	0.08	2155	0.06	3.0e-07	5.74	9.64e-09	0.32	TRUE
Liver	Slc16a6	gene expression	Slc16a6	0.16	1	0.15	5.0e-16	5.9	3.74e-09	0.67	FALSE
Liver	Abca6	isoform ratio	XM_002727835.7	0.22	88	0.29	9.3e-33	5.25	1.56e-07	0.85	FALSE
Liver	Abca6	isoform ratio	XM_006247655.4	0.27	36	0.32	1.0e-35	-5.98	2.20e-09	0.83	FALSE
Liver	Abca6	intron excision ratio	chr10_95209800_95211144	0.07	40	0.07	4.3e-08	5.37	8.03e-08	0.84	FALSE
Liver	Abca6	intron excision ratio	chr10_95209800_95211153	0.08	1	0.06	1.0e-06	6.26	3.74e-10	0.97	FALSE
Liver	Abca6	intron excision ratio	chr10_95209800_95211289	0.23	171	0.23	1.7e-25	-5.99	2.07e-09	0.83	FALSE
Liver	Apoh	mRNA stability	Apoh	0.25	26	0.26	3.5e-28	5.57	2.53e-08	0.63	FALSE
NAcc	Abca9	alternative TSS	XM_039087440.1	0.03	1	0.03	1.9e-04	5.82	5.99e-09	0.17	FALSE
NAcc	Arsg	alternative TSS	XM_006247608.4	0.03	2839	0.02	7.4e-04	5.67	1.41e-08	0.41	FALSE
NAcc	Arsg	alternative TSS	XM_006247608.4	0.04	2839	0.03	2.8e-04	5.57	2.51e-08	0.37	FALSE
NAcc	Abca6	gene expression	Abca6	0.08	50	0.05	8.7e-07	5.36	8.29e-08	0.78	FALSE
NAcc	Abca9	gene expression	Abca9	0.62	104	0.65	6.3e-99	5.69	1.25e-08	0.8	FALSE
NAcc	Amz2	gene expression	Amz2	0.14	95	0.16	1.8e-18	-5.85	5.01e-09	0.55	FALSE
NAcc	Cep112	gene expression	Cep112	0.11	2266	0.1	1.5e-11	-5.46	4.85e-08	0.03	FALSE
NAcc	LOC102550112	gene expression	LOC102550112	0.04	1	0.03	4.3e-04	-6.13	8.77e-10	0.17	FALSE
NAcc	LOC120095201	gene expression	LOC120095201	0.04	2274	0.04	1.3e-05	6.26	3.77e-10	0.68	FALSE
NAcc	Rgs9	gene expression	Rgs9	0.05	2499	0.05	2.7e-06	-6.18	6.24e-10	0.6	FALSE
NAcc	LOC100912202	mRNA stability	LOC100912202	0.03	1	0.04	1.3e-05	-5.66	1.52e-08	0.14	FALSE
OFC	Arsg	alternative polyA	XM_039086177.1	0.3	2839	0.14	4.1e-04	-5.36	8.28e-08	0.36	FALSE
OFC	Wipi1	alternative TSS	XM_039086173.1	0.14	1	0.09	3.2e-03	5.9	3.73e-09	0.06	FALSE
OFC	Abca9	gene expression	Abca9	0.69	35	0.58	8.8e-17	-5.37	7.76e-08	0.73	FALSE
OFC	Amz2	gene expression	Amz2	0.16	15	0.16	1.4e-04	5.83	5.46e-09	0.54	FALSE
PL	Abca9	alternative TSS	XM_039087443.1	0.05	17	0.04	4.1e-05	6.12	9.55e-10	0.61	FALSE
PL	Arsg	alternative TSS	XM_008768369.2	0.04	2839	0.02	9.4e-04	-5.53	3.26e-08	0.34	FALSE
PL	Map2k6	alternative TSS	NM_053703.3	0.1	1	0.17	2.0e-18	-6.18	6.47e-10	0.96	TRUE
PL	Map2k6	alternative TSS	XM_039085033.1	0.13	1	0.22	6.0e-24	6.18	6.47e-10	0.96	FALSE
PL	Abca6	gene expression	Abca6	0.1	39	0.14	2.7e-15	5.73	1.01e-08	0.81	FALSE
PL	Abca9	gene expression	Abca9	0.69	53	0.61	7.2e-86	6.07	1.25e-09	0.86	FALSE
PL	Amz2	gene expression	Amz2	0.31	1	0.22	1.3e-23	-5.76	8.65e-09	0.47	FALSE
PL	Cep112	gene expression	Cep112	0.18	141	0.2	1.3e-21	5.72	1.04e-08	0.61	FALSE
PL	LOC120095201	gene expression	LOC120095201	0.05	2274	0.02	3.9e-03	6.28	3.37e-10	0.55	FALSE
PL	Map2k6	intron excision ratio	chr10_95373426_95448972	0.24	14	0.35	6.8e-40	5.95	2.69e-09	0.76	FALSE
PL	Map2k6	intron excision ratio	chr10_95447514_95448972	0.24	14	0.34	4.9e-39	-5.98	2.25e-09	0.75	FALSE
pVTA	Abca9	alternative TSS	XM_039087443.1	0.12	3146	0.06	8.9e-04	5.44	5.25e-08	0.66	FALSE
pVTA	Abca9	gene expression	Abca9	0.64	1	0.5	9.8e-25	5.66	1.50e-08	0.5	FALSE
pVTA	Amz2	gene expression	Amz2	0.12	1	0.07	5.5e-04	-6.13	8.98e-10	0.22	FALSE
pVTA	Fam20a	gene expression	Fam20a	0.31	2993	0.22	5.5e-10	-5.35	8.56e-08	0.59	FALSE
pVTA	Arsg	intron excision ratio	chr10_94460446_94461943	0.28	2839	0.15	4.6e-07	5.54	2.96e-08	0.39	FALSE
RMTg	Arsg	alternative polyA	XM_008768369.2	0.13	1	0.07	6.2e-03	-6.13	8.74e-10	0.08	FALSE
RMTg	Arsg	alternative polyA	XM_039086177.1	0.14	11	0.07	5.1e-03	-5.7	1.21e-08	0.23	FALSE
RMTg	Abca9	gene expression	Abca9	0.38	15	0.32	2.0e-09	-6.45	1.11e-10	0.82	TRUE
RMTg	Wipi1	gene expression	Wipi1	0.16	2923	0.1	1.2e-03	5.22	1.77e-07	0.29	FALSE