Hub : Genes

Ccdc167

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Ccdc167 0.14 0.12 7.3e-03 0.04 0.03 0.01 0.03 4.9e-02 5.3e-02 2.0e-01 8.7e-02
2 Adipose gene expression Ccdc167 0.2 0.12 0.0e+00 0.26 0.26 0.26 0.26 2.9e-29 5.0e-29 3.4e-29 5.1e-29
3 IL gene expression Ccdc167 0.25 0.17 2.1e-04 0.11 0.09 0.07 0.1 1.3e-03 3.4e-03 1.1e-02 1.9e-03
4 PL gene expression Ccdc167 0.19 0.08 0.0e+00 0.18 0.17 0.18 0.17 1.8e-19 2.5e-18 3.2e-19 1.1e-18
5 IC gene expression Ccdc167 0.14 0.09 8.0e-05 0.12 0.09 0.1 0.1 1.4e-05 1.2e-04 4.9e-05 4.1e-05
6 RMTg gene expression Ccdc167 0.16 0.13 7.5e-03 0.06 0.06 0.02 0.09 1.3e-02 1.3e-02 8.2e-02 2.1e-03
7 pVTA gene expression Ccdc167 0.19 0.1 6.7e-15 0.16 0.17 0.16 0.16 1.3e-12 2.1e-13 9.6e-13 1.6e-12
8 OFC gene expression Ccdc167 0.21 0.17 3.4e-04 0.11 0.12 0.1 0.14 1.4e-03 8.4e-04 2.1e-03 3.0e-04
9 Brain gene expression Ccdc167 0.22 0.12 0.0e+00 0.21 0.23 0.22 0.22 4.4e-19 5.6e-21 1.5e-20 2.0e-20
10 NAcc gene expression Ccdc167 0.28 0.18 0.0e+00 0.22 0.24 0.24 0.24 2.5e-33 8.3e-36 2.4e-35 1.9e-35
11 BLA gene expression Ccdc167 0.17 0.09 2.6e-12 0.24 0.24 0.24 0.24 6.6e-13 3.4e-13 8.4e-13 8.2e-13
12 Liver gene expression Ccdc167 0.38 0.24 0.0e+00 0.27 0.27 0.27 0.27 4.2e-30 9.1e-30 2.0e-30 4.7e-30

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.91.51.9-1.3-1.1-1.0-1.4-1.2-1.4-1.2-1.3-1.2-1.2-1.1-1.3
Area under the delay curve0.91.01.70.81.31.31.01.10.80.90.91.11.01.10.7
BMI with tail3.010.211.63.33.12.83.43.23.43.23.33.23.23.13.1
BMI without tail2.37.17.92.72.62.52.82.32.82.82.62.72.72.72.6
Body weight5.825.526.65.15.15.15.24.95.15.05.05.05.14.94.8
Weight adjusted by age2.23.44.22.11.70.82.01.81.92.11.82.01.72.02.0
Bone surface0.00.00.00.00.2-0.1-0.00.0-0.00.00.00.1-0.00.1-0.1
Bone volume0.00.00.0-0.10.10.1-0.1-0.0-0.1-0.0-0.10.10.00.1-0.2
Breakpoint value in progressive ratio session0.10.10.2-0.20.4-0.2-0.3-0.3-0.2-0.3-0.4-0.4-0.3-0.4-0.1
Number of licking bursts0.30.50.7-0.7-0.7-0.8-0.7-0.8-0.7-0.7-0.8-0.7-0.8-0.6-0.8
Context. condit. distance diff. score0.10.20.3-0.3-0.2-0.5-0.5-0.4-0.4-0.4-0.4-0.5-0.4-0.5-0.0
Locomotion velocity, session 11.01.12.1-1.0-0.9-0.9-0.9-0.9-0.9-1.2-0.9-1.3-1.0-1.4-1.0
Locomotion distance, session 13.64.55.0-2.1-2.2-2.2-2.1-2.2-2.0-2.1-2.2-2.1-2.1-2.1-2.1
Locomotion velocity, session 20.30.30.5-0.5-0.3-0.7-0.6-0.6-0.6-0.6-0.6-0.5-0.6-0.5-0.6
Locomotion distance, session 20.81.11.7-1.0-1.3-1.3-1.0-1.2-1.0-1.0-1.1-1.0-1.0-1.0-1.0
Locomotion velocity, session 30.00.00.30.10.30.50.10.00.10.00.0-0.00.2-0.10.2
Locomotion distance, session 30.50.50.6-0.7-0.7-0.5-0.8-0.8-0.7-0.8-0.8-0.8-0.6-0.8-0.8
Stereotopy head waving bouts, day 31.82.12.51.51.31.61.41.41.51.41.41.41.51.31.6
Stereotopy head waving duration, day 30.40.50.70.70.50.40.70.70.70.70.70.70.70.70.9
Locomotion velocity, session 70.20.30.5-0.6-0.5-0.1-0.7-0.6-0.6-0.4-0.6-0.3-0.4-0.2-0.7
Locomotion distance, session 71.31.62.2-1.4-1.4-1.0-1.4-1.4-1.3-1.2-1.4-1.0-1.1-0.9-1.5
Stereotopy head waving bouts, day 70.50.61.20.70.91.10.60.70.70.70.70.70.80.70.9
Stereotopy head waving duration, day 70.60.81.30.80.91.10.70.80.80.80.70.80.90.81.0
Locomotion velocity, session 80.00.00.1-0.00.3-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.20.1
Locomotion distance, session 80.71.01.6-0.9-0.9-1.3-1.1-1.1-1.0-0.9-1.1-1.0-1.0-1.0-0.7
Degree of sensitization distance0.10.10.30.20.00.10.20.10.20.40.10.40.20.50.2
Degree of sensitization stereotypy0.20.20.3-0.5-0.1-0.1-0.6-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.2
Conditioned locomotion1.92.23.01.41.41.71.41.31.51.51.31.51.51.51.5
Cocaine response after cond. corrected2.02.43.21.81.61.01.71.51.71.61.61.51.51.51.7
Cocaine response after cond. not corrected1.82.12.71.61.60.91.61.51.61.51.51.41.41.31.6
Cocaine response before conditioning0.10.20.3-0.5-0.30.1-0.4-0.2-0.5-0.5-0.2-0.5-0.3-0.5-0.4
Saline control response0.30.40.70.60.50.80.60.70.60.50.60.50.70.50.7
Bone: connectivity density0.61.01.2-1.1-0.8-0.8-1.1-1.0-1.1-1.0-1.0-1.0-1.0-0.9-1.0
Bone: cortical apparent density0.10.20.3-0.6-0.50.0-0.5-0.4-0.5-0.5-0.4-0.4-0.4-0.4-0.4
Bone: cortical area0.50.81.30.91.20.60.91.00.90.91.00.90.80.90.9
Bone: cortical porosity0.00.00.00.20.10.00.20.00.20.10.10.10.10.10.1
Bone: cortical porosity0.00.00.10.20.10.00.20.10.20.20.20.20.10.20.2
Bone: cortical thickness0.10.20.2-0.4-0.1-0.5-0.4-0.4-0.4-0.4-0.3-0.4-0.5-0.4-0.3
Bone: cortical thickness0.00.00.2-0.0-0.50.20.0-0.1-0.1-0.1-0.0-0.10.0-0.10.2
Bone: cortical tissue density0.10.10.2-0.5-0.50.1-0.4-0.3-0.4-0.4-0.3-0.3-0.3-0.3-0.4
Condit. Reinf. active minus inactive responses1.11.21.5-1.1-1.0-0.7-1.1-1.0-1.2-1.2-1.0-1.2-1.1-1.2-1.1
Condit. Reinf. active-inactive response ratio0.00.00.1-0.2-0.10.0-0.1-0.1-0.3-0.3-0.1-0.3-0.2-0.3-0.3
Condit. Reinf. active responses0.60.71.0-0.9-0.7-0.4-0.8-0.7-0.9-1.0-0.8-1.0-0.8-1.0-0.9
Condit. Reinf. inactive responses0.81.01.3-1.1-0.9-0.7-1.1-1.0-1.1-1.1-1.0-1.1-1.0-1.1-1.0
Incentive salience index mean0.40.50.7-0.8-0.6-0.4-0.7-0.6-0.9-0.8-0.6-0.8-0.8-0.8-0.7
Condit. Reinf. lever presses0.00.00.0-0.10.1-0.1-0.00.1-0.1-0.10.1-0.1-0.1-0.10.0
Condit. Reinf. active minus inactive responses0.81.02.1-0.9-1.0-1.0-0.8-0.9-0.8-1.2-0.9-1.3-1.0-1.5-0.9
Condit. Reinf. active-inactive response ratio0.20.20.7-0.2-0.4-0.7-0.1-0.4-0.2-0.5-0.3-0.7-0.5-0.8-0.2
Condit. Reinf. active responses0.91.22.1-1.1-1.2-0.9-0.9-1.0-1.0-1.3-1.0-1.3-1.0-1.5-1.0
Condit. Reinf. inactive responses0.00.10.1-0.3-0.30.3-0.2-0.1-0.3-0.3-0.1-0.20.0-0.2-0.3
Condit. Reinf. lever presses4.35.97.2-2.4-2.7-2.3-2.3-2.4-2.4-2.6-2.4-2.6-2.3-2.7-2.3
Condit. Reinf. lever reinforcers received1.62.33.6-1.5-1.6-1.3-1.3-1.4-1.4-1.7-1.4-1.7-1.4-1.9-1.4
Conditioned reinforcement - actives0.20.40.80.70.50.90.70.70.70.40.60.40.70.20.7
Conditioned reinforcement - inactives0.00.00.2-0.2-0.4-0.2-0.10.0-0.2-0.2-0.1-0.3-0.2-0.3-0.1
Conditioned locomotion1.11.42.41.11.01.41.21.61.11.01.31.01.20.91.2
Patch foraging indifference point 0 sec0.20.40.60.70.30.70.60.70.60.70.70.70.70.80.4
Patch foraging indifference point AUC0.20.30.6-0.4-0.8-0.3-0.8-0.7-0.4-0.6-0.6-0.6-0.5-0.7-0.3
Delay disc. indifference point, 0s delay0.80.91.51.00.50.61.21.20.71.01.21.00.81.00.9
Delay disc. indifference point, 16s delay0.10.10.7-0.20.80.70.00.2-0.2-0.2-0.1-0.10.1-0.1-0.2
Delay disc. indifference point, 2s delay0.00.00.3-0.1-0.5-0.20.10.1-0.10.10.10.2-0.00.3-0.1
Delay disc. indifference point, 24s delay2.02.25.91.32.41.71.41.31.21.31.21.41.41.41.3
Delay disc. indifference point, 4s delay1.61.72.01.31.41.41.21.41.11.31.21.31.31.41.2
Delay disc. indifference point, 8s delay1.41.62.61.01.21.61.31.41.11.21.21.31.41.41.0
Indifference point function ln k0.00.10.2-0.3-0.3-0.50.1-0.2-0.4-0.1-0.0-0.1-0.30.0-0.4
Indifference point function log k0.00.10.2-0.3-0.3-0.50.1-0.2-0.4-0.1-0.0-0.1-0.30.0-0.4
Patch foraging total patch changes 0 sec0.30.50.70.70.30.70.70.70.60.70.70.80.70.90.5
Patch foraging total patch changes 12 sec0.00.00.10.2-0.40.2-0.10.10.20.00.1-0.00.1-0.10.2
Patch foraging total patch changes 18 sec0.30.51.60.70.41.30.40.50.70.60.50.70.80.70.6
Patch foraging total patch changes 24 sec0.10.20.5-0.3-0.7-0.5-0.5-0.3-0.3-0.3-0.4-0.4-0.4-0.3-0.4
Patch foraging total patch changes 6 sec0.10.10.30.50.30.50.10.50.40.30.40.30.40.30.3
Patch foraging time to switch 0 sec0.91.92.61.51.61.21.51.41.61.31.41.21.41.11.3
Patch foraging water rate 0 sec0.00.10.5-0.2-0.7-0.3-0.2-0.2-0.30.0-0.20.1-0.20.3-0.2
Patch foraging water rate 12 sec0.10.10.3-0.4-0.3-0.3-0.4-0.5-0.5-0.3-0.6-0.2-0.3-0.2-0.4
Patch foraging water rate 18 sec0.50.81.2-1.0-0.6-0.6-0.8-0.8-1.1-0.9-0.9-0.8-0.8-0.8-1.0
Patch foraging water rate 24 sec0.30.40.8-0.7-0.4-0.5-0.6-0.7-0.7-0.6-0.9-0.5-0.6-0.4-0.7
Patch foraging water rate 6 sec0.10.10.4-0.3-0.2-0.2-0.3-0.6-0.3-0.1-0.6-0.1-0.30.0-0.4
Seeking ratio, delayed vs. immediate footshock0.60.71.3-1.20.30.1-0.9-0.8-1.0-1.0-0.8-0.9-0.7-0.8-1.0
Distance traveled before self-admin0.70.91.20.90.71.00.91.10.90.91.01.00.91.00.9
Distance traveled after self-admin0.00.00.10.20.30.10.1-0.20.20.20.00.30.20.30.1
Extensor digitorum longus weight0.20.91.1-1.0-0.9-1.1-0.9-0.9-0.9-1.0-0.9-1.0-1.0-1.1-0.9
Bone: elastic displacement0.00.00.1-0.10.1-0.2-0.2-0.1-0.1-0.2-0.1-0.3-0.2-0.30.0
Bone: elastic work0.10.10.40.30.60.20.30.40.30.30.40.30.30.30.5
Bone: endosteal estimation3.47.48.12.82.72.52.82.82.72.72.82.72.82.72.5
Bone: endosteal perimeter2.45.25.92.42.31.82.42.42.32.32.42.32.22.22.2
Epididymis fat weight0.82.93.51.81.91.71.81.51.91.71.71.61.71.41.7
Delta time in closed arm before/after self-admin4.44.15.32.21.51.52.02.32.22.12.02.02.01.92.3
Delta time in open arm before/after self-admin1.51.41.8-1.3-1.2-0.8-1.2-1.2-1.3-1.3-1.2-1.2-1.1-1.2-1.2
Diff in mean of infusions in LGA sessions0.20.20.6-0.30.0-0.8-0.4-0.6-0.3-0.4-0.6-0.4-0.5-0.4-0.4
Delay discount exponential model param0.70.81.4-0.7-1.2-1.1-0.8-0.9-0.7-0.8-0.7-0.9-0.9-1.0-0.6
Extinction: sum of active levers before priming0.30.30.80.8-0.1-0.30.70.60.80.50.60.20.3-0.00.9
Active lever presses in extinction session 60.10.10.3-0.20.60.20.30.3-0.2-0.30.2-0.3-0.1-0.4-0.0
Bone: final force4.36.87.82.62.82.52.62.82.62.62.72.62.62.62.4
Bone: final moment3.75.96.82.42.62.42.42.62.42.42.52.42.52.42.2
Food consumed during 24 hour testing period1.01.32.21.11.10.81.51.41.11.11.41.01.01.01.2
Glucose0.20.40.70.60.6-0.10.80.60.70.70.60.60.50.70.7
Heart weight0.40.73.1-0.6-0.5-1.8-0.8-0.8-0.6-0.5-0.8-0.6-1.0-0.5-0.5
Delay discount hyperbolic model param0.50.50.8-0.6-0.9-0.9-0.7-0.8-0.5-0.7-0.6-0.8-0.7-0.9-0.5
Intermittent access intake day 1-15 change0.10.20.50.20.70.70.40.70.20.20.50.20.40.10.3
Intermittent access intake escalation0.10.20.70.00.70.90.30.60.00.00.30.10.30.00.1
Intermittent access intake escalation 20.20.20.4-0.5-0.10.0-0.4-0.2-0.5-0.6-0.3-0.5-0.3-0.6-0.5
Intermitt. access day 1 inactive lever presses0.10.63.2-0.4-1.8-1.3-0.4-0.3-0.4-0.4-0.3-0.5-0.7-0.5-0.3
Intermitt. access day 15 inactive lever presses0.00.10.30.20.50.50.10.20.20.10.00.10.30.10.2
Intermitt. access escalation Index0.40.61.0-0.8-0.4-0.7-0.8-1.0-0.8-0.7-0.9-0.7-0.8-0.6-0.9
Intermittent access day 1 total infusions0.50.81.0-0.9-0.5-0.7-1.0-1.0-0.9-1.0-1.0-1.0-0.9-1.0-0.9
Intermittent access day 15 total infusions0.20.20.4-0.60.10.1-0.5-0.3-0.6-0.6-0.5-0.6-0.4-0.6-0.5
Intermittent access terminal intake (last 3 days)0.00.00.1-0.10.30.2-0.10.2-0.1-0.20.0-0.2-0.0-0.2-0.0
Intermittent access total infusions0.30.40.5-0.7-0.3-0.2-0.7-0.6-0.7-0.7-0.7-0.7-0.5-0.7-0.6
Intermittent access day 1 locomotion0.10.10.20.20.50.50.20.40.20.20.20.20.30.20.2
Intermittent access day 15 total locomotion1.52.85.21.52.32.31.52.11.51.21.61.21.70.91.6
Intermittent access total locomotion0.30.31.30.40.61.20.40.80.40.20.50.20.60.00.5
Intermittent access standard deviation0.81.71.91.41.01.31.31.31.41.31.21.21.41.21.4
Left kidney weight2.813.016.33.73.34.03.63.23.73.63.43.73.83.63.4
Right kidney weight4.721.427.74.64.55.34.54.34.64.64.44.84.94.74.2
Cocaine induced anxiety0.20.30.5-0.7-0.5-0.6-0.5-0.6-0.7-0.5-0.6-0.4-0.6-0.3-0.7
Post-drug Anxiety0.60.60.8-0.9-0.4-0.7-0.8-0.8-0.9-0.8-0.8-0.7-0.8-0.7-0.9
Baseline Anxiety0.20.30.50.70.40.10.60.40.70.60.50.50.50.40.7
Tail length0.62.33.81.41.52.01.41.21.41.51.41.61.61.61.4
Length with tail1.67.110.32.62.73.22.62.62.62.62.62.72.82.62.5
Length without tail3.310.511.63.33.23.33.33.43.33.23.43.13.23.03.1
Times rat made contact with spout4.24.86.0-2.2-2.5-1.7-2.2-2.2-2.2-2.3-2.2-2.2-2.1-2.2-2.2
Lifetime Intake0.00.00.1-0.10.00.2-0.1-0.1-0.1-0.2-0.2-0.2-0.0-0.2-0.1
Liver weight, left1.82.94.01.81.31.81.61.41.81.91.51.91.92.01.6
Liver weight, right2.95.16.52.22.12.12.22.12.32.42.22.52.42.52.1
Locomotor activity0.00.10.20.10.30.4-0.00.00.10.30.10.40.30.50.2
Locomotor testing distance0.10.10.40.4-0.10.10.20.20.30.50.20.60.30.60.3
Locomotor testing rearing0.71.41.91.20.81.21.31.21.21.31.11.31.31.41.1
Locomotion in novel chamber0.20.20.6-0.3-0.8-0.5-0.3-0.4-0.6-0.2-0.4-0.2-0.4-0.0-0.6
Locomotion in novel chamber post-restriction1.52.52.91.71.11.61.61.41.51.71.61.71.71.71.5
Fecal boli incidents, locomotor time 10.00.00.1-0.2-0.20.3-0.0-0.10.20.1-0.10.20.20.3-0.1
Change in fecal boli incidents, locomotor task3.63.65.22.31.00.72.21.91.92.12.12.01.71.92.2
Time >=10cm from walls, locomotor time 13.03.24.52.11.21.21.71.72.02.01.71.91.81.92.0
Bouts of movement, locomotor time 10.40.50.8-0.9-0.9-0.4-0.7-0.6-0.4-0.7-0.8-0.7-0.6-0.8-0.8
Total resting periods, locomotor time 10.20.30.4-0.6-0.6-0.2-0.5-0.6-0.2-0.5-0.6-0.6-0.4-0.6-0.6
Rest time, locomotor task time 10.30.30.70.50.30.30.80.50.80.70.70.60.60.60.5
Distance moved, locomotor task time 10.10.10.50.50.40.20.40.70.10.20.50.20.20.10.4
Vertical activity count, locomotor time 10.20.61.00.80.90.80.81.00.50.60.90.70.70.60.7
Time >=10cm from walls, locomotor time 28.011.914.73.82.82.53.53.43.63.73.43.73.33.73.7
Bouts of movement, locomotor time 20.00.10.2-0.1-0.00.2-0.5-0.20.1-0.2-0.5-0.20.0-0.3-0.2
Total resting periods, locomotor time 20.10.20.5-0.3-0.4-0.2-0.7-0.5-0.2-0.4-0.7-0.4-0.3-0.5-0.3
Rest time, locomotor task time 20.10.10.20.10.2-0.00.40.30.30.30.40.20.20.20.2
Distance moved, locomotor task time 22.32.73.71.91.41.51.61.71.81.61.61.61.71.51.7
Vertical activity count, locomotor time 21.11.52.21.51.01.01.31.11.41.31.11.31.21.21.3
Light reinforcement 11.43.54.02.01.71.91.71.71.92.01.62.01.92.02.0
Light reinforcement 22.03.04.01.72.02.01.71.61.71.71.61.81.81.81.5
Bone: marrow area3.57.78.42.82.82.62.82.92.82.82.92.82.82.72.6
Bone: maximum diameter0.71.31.71.21.30.71.21.21.11.21.21.21.11.21.1
Bone: maximum force1.42.63.21.51.81.41.61.71.61.61.71.61.61.61.5
Bone: maximum moment1.12.02.61.41.61.31.41.51.41.41.51.41.41.41.3
Mean time between licks in bursts0.41.01.6-1.1-0.8-1.3-0.8-0.7-1.0-1.0-0.7-1.1-1.1-1.0-0.9
Mean num. licks in bursts0.40.60.8-0.8-0.9-0.4-0.8-0.7-0.8-0.8-0.7-0.8-0.7-0.8-0.7
Cd content in liver0.00.00.1-0.2-0.10.1-0.1-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.2
Co content in liver2.12.52.71.61.41.51.61.41.61.61.61.61.61.61.6
Cu content in liver2.93.54.2-1.9-2.0-2.0-1.9-2.1-1.9-1.7-2.0-1.6-1.9-1.5-1.7
Fe content in liver1.41.72.21.21.31.51.21.31.21.31.21.31.31.31.2
K content in liver0.70.71.1-0.7-1.0-1.0-0.8-1.0-0.7-0.7-0.8-0.7-0.8-0.7-0.7
Mg content in liver0.60.61.2-0.7-0.9-1.1-0.7-0.9-0.7-0.6-0.7-0.6-0.8-0.6-0.6
Mn content in liver0.00.00.10.2-0.00.00.2-0.00.20.20.10.20.10.30.3
Na content in liver0.30.40.5-0.6-0.7-0.6-0.5-0.7-0.5-0.6-0.6-0.6-0.6-0.6-0.6
Rb content in liver0.00.00.00.1-0.00.10.1-0.00.20.10.10.20.10.10.1
Se content in liver1.41.62.3-1.3-1.3-1.5-1.3-1.3-1.3-1.2-1.4-1.1-1.3-1.1-1.2
Sr content in liver0.00.00.0-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0
Zn content in liver0.10.10.4-0.2-0.3-0.6-0.2-0.3-0.2-0.2-0.2-0.2-0.3-0.2-0.2
Bone: minimum diameter2.54.65.82.22.41.52.22.32.22.22.32.12.02.12.1
Time in familiar zone, hab. session 10.10.10.2-0.30.00.1-0.2-0.1-0.2-0.4-0.1-0.4-0.2-0.5-0.1
Time in novel zone, hab. session 10.50.50.90.80.50.40.70.60.70.80.70.90.71.00.5
Total zone transitions, hab. session 13.34.66.0-2.0-2.4-2.2-2.1-2.3-2.0-2.1-2.2-2.2-2.1-2.2-1.9
Total locomotion distance, hab. session 12.02.83.7-1.6-1.9-1.8-1.6-1.6-1.6-1.7-1.6-1.7-1.7-1.8-1.4
Locomotion velocity, hab. session 11.82.53.5-1.4-1.9-1.8-1.5-1.6-1.5-1.6-1.6-1.6-1.6-1.7-1.3
Time in familiar zone, hab. session 21.31.31.7-1.1-1.2-1.2-1.3-1.3-1.2-1.1-1.3-1.0-1.1-0.9-1.2
Time in novel zone, hab. session 21.11.11.71.10.91.31.21.01.20.91.00.91.20.71.0
Total zone transitions, hab. session 20.40.50.9-0.7-0.9-0.9-0.7-0.9-0.6-0.6-0.9-0.5-0.6-0.5-0.6
Total locomotion distance, hab. session 22.33.04.5-1.7-2.1-1.9-1.7-1.9-1.6-1.6-1.9-1.6-1.6-1.6-1.5
Locomotion velocity, hab. session 22.83.75.4-1.9-2.3-2.1-1.9-2.1-1.8-1.8-2.1-1.7-1.8-1.7-1.7
Novel to familiar place preference ratio0.70.81.21.00.80.51.10.91.00.91.00.80.80.71.1
Novelty place preference0.60.61.00.90.70.41.00.80.90.80.80.70.70.61.0
Time in novel zone, NPP test0.60.61.00.90.70.51.00.80.90.70.90.60.70.50.9
Total zone transitions, NPP test1.31.92.7-1.4-1.6-1.6-1.4-1.6-1.3-1.2-1.5-1.2-1.3-1.1-1.4
Total locomotion distance, NPP test1.11.52.4-1.1-1.5-1.4-1.2-1.4-1.1-1.0-1.4-1.0-1.1-0.9-1.3
Locomotion velocity, NPP test1.52.23.4-1.4-1.9-1.8-1.5-1.7-1.4-1.2-1.7-1.2-1.4-1.1-1.3
Intraocular pressure0.71.02.40.81.21.61.01.20.80.81.00.91.10.90.7
Delta distance traveled before/after self-admin0.40.41.1-0.5-0.6-0.9-0.5-1.1-0.5-0.5-0.6-0.6-0.7-0.5-0.5
Delta ambulatory time before/after self-admin0.50.61.5-0.6-0.5-1.0-0.7-1.2-0.6-0.6-0.8-0.6-0.7-0.6-0.7
Parametrial fat weight1.63.78.41.81.92.91.91.81.81.71.71.72.21.61.6
Pavlov. Cond. lever latency0.20.30.40.60.50.60.60.40.60.50.40.50.70.40.4
Pavlov. Cond. magazine entry latency0.30.40.5-0.7-0.7-0.5-0.6-0.5-0.7-0.6-0.6-0.6-0.6-0.6-0.7
Pavlov. Cond. change in total contacts0.50.50.80.60.90.90.80.90.60.50.90.50.60.40.6
Pavlov. Cond. index score0.00.00.0-0.2-0.1-0.1-0.10.0-0.2-0.10.0-0.1-0.1-0.0-0.1
Pavlov. Cond. latency score0.00.00.0-0.00.0-0.00.10.2-0.00.10.20.20.00.20.1
Pavlov. Cond. lever contacts0.00.00.0-0.2-0.1-0.2-0.10.0-0.2-0.10.0-0.1-0.2-0.0-0.0
Pavlov. Cond. magazine entry number0.50.60.80.80.80.80.70.60.80.80.70.80.80.70.9
Pavlov. Cond. intertrial magazine entries0.20.20.4-0.3-0.1-0.4-0.4-0.4-0.4-0.5-0.4-0.5-0.4-0.6-0.4
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.2-0.1-0.1-0.10.0-0.2-0.1-0.0-0.1-0.1-0.0-0.2
Pavlov. Cond. response bias0.60.81.0-1.0-0.8-0.9-0.9-0.7-0.9-1.0-0.7-1.0-0.9-1.0-1.0
Pavlov. Cond. lever latency2.73.74.82.02.21.41.81.82.02.01.92.01.72.02.0
Pavlov. Cond. magazine entry latency0.10.10.40.0-0.00.60.20.30.1-0.00.40.00.2-0.10.1
Pavlov. Cond. change in total contacts1.32.12.9-1.5-1.7-1.0-1.3-1.5-1.4-1.6-1.5-1.6-1.3-1.6-1.3
Pavlov. Cond. index score0.81.01.7-1.1-1.3-0.5-0.8-0.8-1.0-1.2-0.8-1.1-0.9-1.2-1.0
Pavlov. Cond. latency score0.50.71.2-0.9-1.1-0.4-0.7-0.6-0.9-1.0-0.6-1.0-0.7-1.0-0.8
Pavlov. Cond. lever contacts2.23.14.4-1.9-2.1-1.2-1.6-1.7-1.8-1.9-1.7-1.8-1.6-1.9-1.8
Pavlov. Cond. magazine entry number0.00.00.10.20.3-0.30.10.00.20.20.00.20.00.20.2
Pavlov. Cond. intertrial magazine entries0.60.81.4-0.9-1.1-1.2-0.8-0.9-0.9-0.8-1.0-0.8-0.9-0.7-1.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.4-1.0-1.2-0.4-0.7-0.7-0.9-1.0-0.7-1.0-0.7-1.0-0.9
Pavlov. Cond. response bias1.41.82.6-1.5-1.6-0.7-1.3-1.3-1.4-1.5-1.3-1.5-1.2-1.5-1.3
Time in closed arm before self-admin0.20.31.1-0.4-0.8-0.9-0.4-1.1-0.4-0.3-0.5-0.3-0.5-0.2-0.4
Time in closed arm after self-admin0.50.50.90.90.20.10.80.40.90.80.70.70.60.71.0
Time in open arm before self-admin0.20.20.4-0.5-0.1-0.3-0.6-0.3-0.5-0.5-0.7-0.5-0.5-0.5-0.5
Time in open arm after self-admin2.12.33.1-1.7-1.2-0.9-1.7-1.4-1.7-1.6-1.7-1.5-1.4-1.4-1.7
Bone: periosteal estimation2.34.85.62.22.41.82.22.32.22.22.32.22.22.12.1
Bone: periosteal perimeter1.12.02.51.41.61.01.51.51.41.41.51.41.31.31.4
Bone: post-yield work0.30.40.50.70.70.40.60.60.60.60.70.60.60.60.6
Progressive ratio test 1 active lever presses0.10.10.30.50.00.10.40.30.50.40.30.30.30.20.5
Progressive ratio test 1 breakpoint0.10.10.20.4-0.1-0.10.30.20.40.30.20.30.20.20.4
Progressive ratio test 1 inactive lever presses0.30.40.80.70.40.60.60.90.70.50.70.40.60.30.7
Progressive ratio test 2 active lever presses0.00.10.3-0.0-0.30.20.0-0.1-0.0-0.3-0.1-0.4-0.0-0.50.1
Progressive ratio test 2 breakpoint0.10.10.4-0.1-0.30.1-0.1-0.2-0.1-0.4-0.2-0.5-0.1-0.6-0.0
Progressive ratio test 2 inactive lever presses0.10.20.4-0.4-0.6-0.2-0.4-0.3-0.4-0.5-0.4-0.5-0.4-0.6-0.4
Incentive Sensitization - Responses1.11.52.2-1.2-1.1-0.9-1.1-1.2-1.2-1.4-1.2-1.4-1.2-1.5-1.1
Incentive Sensitization - Breakpoint0.81.11.7-1.1-0.9-0.6-1.0-1.1-1.1-1.2-1.0-1.2-1.0-1.3-1.0
Sum of active levers in priming session hrs 5-60.20.20.4-0.30.2-0.6-0.3-0.3-0.3-0.5-0.4-0.5-0.5-0.6-0.3
Progressive ratio1.11.74.01.11.42.01.11.21.11.21.21.21.51.21.2
Food seeking constrained by brief footshock0.10.10.2-0.3-0.3-0.2-0.3-0.5-0.4-0.3-0.3-0.2-0.3-0.2-0.3
Seeking ratio, punishment vs. effort0.40.62.5-0.6-1.0-1.6-0.5-0.7-0.6-0.6-0.6-0.7-0.9-0.6-0.6
Retroperitoneal fat weight0.83.55.21.82.02.32.01.81.81.71.81.82.01.71.7
Reaction time number correct0.10.21.50.20.41.20.40.70.30.20.40.20.50.20.2
Reaction time mean minus median0.10.20.4-0.4-0.30.5-0.4-0.6-0.3-0.5-0.4-0.4-0.1-0.5-0.4
Reaction time mean minus median AUC0.00.10.4-0.30.10.6-0.2-0.4-0.2-0.3-0.3-0.30.0-0.3-0.2
Reaction time num false alarms0.30.41.1-0.7-1.0-0.4-0.7-0.4-0.7-0.6-0.6-0.6-0.6-0.6-0.6
Reaction time num false alarms AUC0.81.22.2-1.1-1.5-1.1-1.2-0.8-1.1-1.1-1.1-1.1-1.1-1.0-1.0
Reaction time trials correct on left0.10.21.50.20.41.20.40.70.30.20.40.20.50.20.2
Reaction time trials on left0.10.21.40.20.31.20.30.70.30.10.40.20.50.10.1
Reaction time mean0.10.20.40.40.40.70.4-0.00.50.30.20.30.50.20.4
Reaction time mean AUC0.20.31.00.60.71.00.60.20.70.50.40.50.70.40.5
Median of all reaction times0.30.40.60.70.60.70.60.30.80.60.50.60.70.50.7
Reaction time omissions0.00.10.2-0.3-0.00.2-0.1-0.2-0.2-0.4-0.2-0.3-0.1-0.4-0.3
Reaction time false alarm rate1.01.32.6-1.1-1.5-1.6-1.2-1.1-1.1-1.0-1.1-1.0-1.3-0.9-0.9
Reaction time premature initiation rate0.10.10.4-0.1-0.6-0.4-0.4-0.3-0.1-0.2-0.2-0.2-0.3-0.3-0.1
Reaction time premature initiations0.00.00.10.2-0.20.3-0.00.20.20.10.20.00.1-0.10.1
Std. dev. reaction times0.10.10.5-0.3-0.10.3-0.4-0.7-0.2-0.4-0.5-0.4-0.2-0.4-0.4
Reaction time trials completed0.10.21.40.20.31.20.30.70.30.10.40.20.50.10.1
Reaction time trials AUC0.10.21.40.20.41.20.30.60.30.20.40.20.50.10.1
Run reversals in cocaine runway, females0.00.00.30.10.30.50.20.3-0.1-0.00.10.00.2-0.00.1
Run reversals in cocaine runway, males0.80.81.4-1.0-0.20.2-1.2-1.1-0.9-1.0-1.1-0.9-0.6-0.9-1.1
Latency to leave start box in cocaine runway0.20.21.10.6-0.5-1.10.50.10.30.30.40.0-0.1-0.10.7
Latency to leave start box in cocaine runway, F0.20.20.70.7-0.2-0.60.50.20.50.30.50.10.1-0.10.8
Latency to leave start box in cocaine runway, M0.20.20.30.5-0.1-0.50.50.40.20.40.50.40.20.40.4
Std. dev. time between licks in bursts1.72.43.61.61.40.51.91.71.81.61.71.41.41.31.6
Total sessions with >9 infusions0.00.00.00.0-0.00.00.10.20.0-0.1-0.0-0.1-0.0-0.10.1
Short access day 1 total inactive lever presses0.00.00.00.0-0.00.1-0.00.00.0-0.1-0.1-0.20.0-0.20.0
Short access day 10 total inactive lever presses0.41.01.1-1.0-1.0-0.9-1.0-0.8-1.0-1.0-1.0-1.0-1.0-0.9-1.0
Short access day 1 total infusions0.10.10.5-0.2-0.7-0.5-0.2-0.3-0.2-0.3-0.3-0.4-0.4-0.4-0.2
Short access day 10 total infusions0.50.70.9-0.9-0.6-0.3-0.9-0.5-0.9-0.9-0.9-0.9-0.7-0.8-0.9
Short access total infusions0.00.00.00.1-0.20.10.10.10.1-0.10.0-0.10.0-0.20.1
Short access day 1 locomotion0.10.10.20.3-0.1-0.30.40.40.30.20.40.10.10.00.4
Short access day 10 total locomotion0.30.60.90.8-0.9-0.60.80.90.80.80.90.60.40.60.8
Short access total locomotion0.40.51.10.8-0.1-0.10.91.10.80.80.90.60.50.60.9
One hour access (0.3 mA shock)2.32.63.5-1.5-1.7-1.6-1.6-1.5-1.5-1.7-1.6-1.8-1.6-1.9-1.4
Compulsive drug intake0.91.13.3-0.8-1.4-1.8-0.9-0.9-0.8-0.8-1.0-0.9-1.2-0.9-0.7
One hour access (shock baseline)0.40.71.0-0.9-0.10.2-0.9-0.7-0.9-1.0-0.8-0.9-0.6-1.0-0.9
Social response proportion0.40.41.10.50.4-0.10.70.70.60.80.80.90.51.10.3
Social responses0.10.20.20.40.2-0.10.50.40.50.50.40.40.30.50.4
Social time0.30.40.6-0.6-0.6-0.8-0.6-0.7-0.6-0.6-0.6-0.7-0.6-0.7-0.4
Soleus weight0.92.73.51.71.91.01.81.61.71.71.71.71.51.71.7
Bone: stiffness1.01.71.91.21.31.31.31.31.21.31.31.41.41.41.1
Tibialis anterior weight0.51.72.5-1.2-1.2-1.6-1.2-1.2-1.2-1.3-1.2-1.4-1.4-1.5-1.1
Time to tail flick, vehicle, before self-admin0.50.62.20.41.41.50.60.60.40.40.50.50.80.50.2
Time to tail flick, vehicle, after self-admin0.30.41.0-0.5-0.6-0.8-0.8-1.0-0.5-0.4-0.8-0.5-0.6-0.4-0.5
Time to tail flick, test, before self-admin0.60.61.0-1.0-0.5-0.4-0.6-0.5-1.0-0.9-0.5-0.8-0.8-0.8-1.0
Time to tail flick, test, after self-admin1.61.63.0-1.3-0.4-0.2-1.6-1.7-1.3-1.3-1.7-1.2-0.9-1.1-1.5
Delta time to tail flick, vehicle, before/after SA1.31.32.0-1.0-1.3-1.4-1.3-1.3-1.0-0.9-1.2-1.0-1.1-0.9-0.9
Delta time to tail flick, test, before/after SA0.30.30.80.50.70.90.1-0.00.50.50.00.60.70.60.3
Tibia length2.05.56.42.42.32.52.22.32.32.42.32.42.42.42.2
Ambulatory time before self-admin0.10.10.30.30.10.40.30.50.30.30.40.30.30.30.4
Ambulatory time after self-admin0.20.20.7-0.5-0.2-0.4-0.6-0.8-0.5-0.4-0.7-0.3-0.4-0.3-0.4
Bone: tissue strength0.00.00.10.10.3-0.00.10.20.10.20.10.20.10.30.0
Total heroin consumption1.21.51.7-1.3-0.6-1.2-1.2-1.1-1.3-1.3-1.3-1.3-1.3-1.2-1.3
Bone: trabecular number1.22.02.5-1.6-1.2-1.2-1.5-1.4-1.6-1.4-1.5-1.4-1.4-1.3-1.4
Bone: trabecular spacing2.12.73.31.61.51.61.61.51.71.71.61.81.71.81.5
Bone: trabecular thickness0.10.10.50.10.30.70.10.10.10.10.00.20.30.20.2
Bone: trabecular tissue density0.10.10.2-0.4-0.40.2-0.3-0.4-0.3-0.3-0.4-0.3-0.2-0.3-0.2
Water consumed over 24 hours0.50.61.4-0.7-0.7-1.2-0.6-0.6-0.7-0.8-0.7-0.9-0.9-0.9-0.7
Number of responses in last shaping day1.01.11.71.20.0-0.81.21.21.21.21.31.00.61.01.2