Hub : Genes

RT1-N3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression RT1-N3 0.4 0.13 0.0e+00 0.31 0.34 0.33 0.32 2.7e-29 4.3e-32 2.8e-31 5.5e-31
2 pVTA gene expression RT1-N3 0.32 0.11 0.0e+00 0.25 0.26 0.27 0.28 5.0e-20 2.9e-21 1.2e-21 5.8e-23
3 IC gene expression RT1-N3 0.47 0.13 0.0e+00 0.11 0.36 0.35 0.33 2.8e-05 7.8e-16 2.9e-15 1.2e-14
4 NAcc gene expression RT1-N3 0.37 0.1 0.0e+00 0.28 0.34 0.35 0.34 2.4e-43 7.2e-53 1.8e-55 1.5e-53
5 PL gene expression RT1-N3 0.52 0.1 0.0e+00 0.37 0.48 0.49 0.49 4.2e-42 1.4e-59 2.3e-61 3.8e-61
6 Liver isoform ratio NM_001008855.2 0.08 0.05 2.7e-06 0 0.04 0.03 0.03 1.4e-01 4.4e-05 4.4e-04 4.5e-04
7 BLA gene expression RT1-N3 0.56 0.12 0.0e+00 0.29 0.37 0.37 0.37 8.7e-16 1.5e-20 1.9e-20 9.0e-21
8 Brain isoform ratio NM_001008855.2 0.1 0.06 4.8e-07 0.03 0.08 0.07 0.06 1.4e-03 1.0e-07 8.7e-07 1.9e-06
9 IL gene expression RT1-N3 0.86 0.1 2.2e-08 0.24 0.31 0.25 0.26 1.7e-06 2.8e-08 9.5e-07 4.5e-07
10 Adipose isoform ratio XM_006255908.5 0.12 0.09 6.0e-09 0.06 0.07 0.08 0.07 1.0e-06 1.9e-08 5.1e-09 4.2e-08
11 Adipose isoform ratio XM_039098420.2 0.03 0.02 6.5e-04 0.02 0.01 0.01 0.01 5.5e-03 1.3e-02 2.3e-02 1.4e-02
12 IC isoform ratio XM_039098420.2 0.09 0.06 3.4e-03 0.04 0.02 0.04 0.03 9.5e-03 4.2e-02 5.7e-03 1.8e-02
13 BLA isoform ratio XM_006255908.5 0.05 0.04 9.9e-03 0.01 0.02 0 0.01 7.3e-02 4.4e-02 2.5e-01 7.9e-02
14 pVTA isoform ratio NM_001008855.2 0.04 0.03 4.5e-03 0.02 0.02 0.01 0.01 1.2e-02 1.6e-02 2.3e-02 6.9e-02
15 pVTA intron excision ratio chr20_2668772_2668950 0.07 0.06 2.2e-05 0.05 0.05 0.05 0.05 9.5e-05 5.3e-05 8.0e-05 9.9e-05
16 IC isoform ratio NM_001008855.2 0.18 0.11 4.3e-06 0.08 0.05 0.08 0.02 2.9e-04 3.1e-03 4.2e-04 4.2e-02
17 NAcc isoform ratio NM_001008855.2 0.03 0.02 5.3e-04 0.02 0.01 0 0.02 1.4e-04 1.8e-03 6.1e-02 9.0e-04
18 Adipose gene expression RT1-N3 0.35 0.13 0.0e+00 0.31 0.32 0.33 0.33 9.8e-35 1.7e-36 1.1e-37 2.0e-37
19 NAcc isoform ratio XM_039098420.2 0.03 0.03 1.4e-04 0.02 0.02 0.02 0.02 1.4e-03 2.3e-04 1.4e-03 8.5e-04
20 pVTA isoform ratio XM_039098420.2 0.06 0.05 4.0e-04 0.05 0.03 0.04 0.05 8.3e-05 9.4e-04 7.9e-04 9.9e-05
21 PL isoform ratio NM_001008855.2 0.06 0.04 1.4e-06 0.05 0.05 0.04 0.04 3.5e-06 7.7e-06 7.3e-05 1.1e-05
22 BLA isoform ratio XM_039098420.2 0.08 0.06 9.2e-04 0.05 0.04 0.04 0.04 1.4e-03 4.3e-03 4.8e-03 2.4e-03
23 OFC gene expression RT1-N3 0.76 0.14 4.0e-12 0.13 0.42 0.46 0.42 6.8e-04 4.9e-11 2.8e-12 4.0e-11
24 PL isoform ratio XM_039098420.2 0.04 0.04 7.8e-04 0.01 0.02 0.02 0.01 1.4e-02 4.9e-03 2.5e-03 3.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.50.92.9-1.4-1.5-1.0-0.9-0.70.9-0.80.7-1.10.4-0.81.3-1.0-0.81.1-0.7-0.8-1.70.70.9-0.90.9-0.10.3
Area under the delay curve1.21.43.7-0.10.1-0.4-0.4-0.60.5-0.60.7-0.3-1.31.6-1.71.51.5-1.51.31.31.5-1.5-1.91.6-1.3-1.1-1.3
BMI with tail1.75.78.5-1.7-1.6-2.2-2.3-2.52.3-2.42.5-2.0-2.92.6-2.42.52.7-2.52.42.51.4-2.7-2.62.6-2.4-2.4-2.5
BMI without tail2.78.213.7-0.9-0.8-1.7-1.9-2.22.1-2.22.3-1.5-3.23.7-3.63.53.7-3.53.63.52.5-3.5-3.53.7-3.4-1.9-2.9
Body weight3.113.631.01.92.30.60.2-0.40.0-0.00.50.8-3.44.6-5.55.15.0-5.24.44.55.6-4.4-4.84.8-4.3-1.5-4.1
Weight adjusted by age1.21.84.91.21.50.80.70.5-0.60.4-0.40.7-0.81.9-1.61.61.3-1.71.51.92.2-1.4-1.71.3-1.7-0.8-1.6
Bone surface0.10.20.70.80.90.80.60.7-0.60.6-0.60.60.40.2-0.40.20.1-0.20.20.10.30.0-0.10.0-0.10.7-0.3
Bone volume0.10.10.3-0.2-0.1-0.2-0.3-0.20.3-0.30.3-0.3-0.20.5-0.40.40.5-0.40.60.40.2-0.4-0.40.3-0.4-0.1-0.6
Breakpoint value in progressive ratio session0.40.52.50.30.10.40.40.5-0.40.3-0.40.60.3-0.70.9-0.7-0.40.7-0.5-0.8-0.40.80.7-0.60.61.61.5
Number of licking bursts0.71.11.71.11.01.31.31.3-1.31.3-1.31.21.3-1.00.7-0.9-1.00.8-1.0-1.0-0.31.01.0-1.00.81.21.0
Context. condit. distance diff. score7.89.515.22.01.72.72.83.0-2.82.9-3.02.23.9-3.43.1-3.4-3.43.3-3.4-3.4-2.33.53.4-3.43.53.22.9
Locomotion velocity, session 10.60.60.90.70.60.80.80.9-0.90.9-0.90.70.8-0.90.7-0.8-1.00.7-0.9-0.8-0.50.80.8-0.80.80.60.8
Locomotion distance, session 10.50.61.8-1.3-1.3-1.2-1.1-1.01.1-1.11.0-1.2-0.80.00.5-0.2-0.20.2-0.1-0.0-0.9-0.10.0-0.00.0-0.8-0.3
Locomotion velocity, session 20.10.10.30.50.50.50.50.5-0.60.5-0.50.50.2-0.40.3-0.3-0.40.2-0.4-0.3-0.00.30.3-0.30.30.20.3
Locomotion distance, session 20.10.20.6-0.5-0.5-0.4-0.2-0.20.2-0.30.2-0.4-0.2-0.40.7-0.5-0.60.5-0.5-0.5-0.80.40.4-0.40.4-0.30.2
Locomotion velocity, session 30.50.51.1-0.9-0.9-1.0-1.0-1.01.0-0.91.0-1.0-0.80.6-0.40.50.5-0.40.50.60.0-0.6-0.60.5-0.5-0.7-0.6
Locomotion distance, session 30.60.71.8-0.5-0.6-0.2-0.1-0.00.10.0-0.0-0.30.8-0.91.1-1.1-0.91.1-1.0-1.0-1.31.01.0-0.91.10.50.8
Stereotopy head waving bouts, day 30.80.92.71.51.61.21.01.0-1.10.9-0.91.2-0.40.7-1.20.90.6-1.00.70.81.6-0.5-0.60.7-0.70.3-0.4
Stereotopy head waving duration, day 30.50.61.71.11.10.80.60.6-0.70.5-0.50.8-0.60.8-1.00.90.6-0.90.70.81.3-0.6-0.70.7-0.7-0.1-0.5
Locomotion velocity, session 72.83.15.9-0.2-0.40.40.50.7-0.60.7-0.80.12.0-2.32.4-2.3-2.32.4-2.3-2.3-2.42.12.2-2.32.21.21.7
Locomotion distance, session 71.92.46.2-0.8-1.0-0.3-0.20.00.10.1-0.1-0.51.6-1.92.2-2.1-1.92.1-2.0-2.0-2.51.81.9-1.91.90.81.4
Stereotopy head waving bouts, day 71.51.74.60.60.80.2-0.0-0.1-0.0-0.10.20.2-1.31.6-1.91.71.6-1.81.71.72.1-1.5-1.61.6-1.7-0.7-1.2
Stereotopy head waving duration, day 71.41.74.30.70.80.2-0.0-0.1-0.0-0.10.20.3-1.41.7-1.91.81.6-1.81.71.72.1-1.5-1.61.6-1.7-0.7-1.3
Locomotion velocity, session 83.94.69.93.03.03.03.13.0-3.13.0-3.02.91.9-1.40.6-1.1-1.41.0-1.5-1.50.41.61.4-1.41.52.01.5
Locomotion distance, session 83.95.78.21.41.32.02.22.3-2.12.2-2.31.62.9-2.72.5-2.7-2.82.6-2.8-2.7-1.82.82.7-2.72.82.32.2
Degree of sensitization distance0.91.01.50.90.91.11.11.1-1.11.1-1.10.91.2-1.00.8-0.9-1.10.8-1.0-1.0-0.40.90.9-1.00.90.80.7
Degree of sensitization stereotypy0.80.81.70.10.3-0.2-0.3-0.30.3-0.40.4-0.2-1.11.1-1.21.21.2-1.21.21.21.3-1.1-1.11.1-1.2-0.6-0.9
Conditioned locomotion0.30.31.00.80.80.50.50.4-0.60.4-0.40.8-0.60.6-0.70.60.5-0.70.60.61.0-0.5-0.50.5-0.5-0.4-0.3
Cocaine response after cond. corrected0.20.30.8-0.4-0.4-0.2-0.1-0.10.1-0.00.1-0.30.5-0.60.9-0.7-0.60.7-0.7-0.6-0.90.60.6-0.60.70.20.5
Cocaine response after cond. not corrected0.30.30.90.90.90.90.90.8-0.80.8-0.80.90.4-0.2-0.0-0.1-0.20.0-0.2-0.20.30.20.2-0.20.20.60.3
Cocaine response before conditioning2.12.57.02.12.11.41.11.0-1.20.9-0.91.6-1.01.5-2.31.91.5-2.01.51.52.6-1.4-1.61.5-1.60.2-0.9
Saline control response2.63.44.3-1.3-1.3-1.7-1.9-1.91.9-1.91.9-1.6-2.02.0-1.91.92.0-1.92.02.00.9-2.1-2.01.9-2.0-1.8-1.9
Bone: connectivity density1.21.94.7-0.6-0.8-0.00.00.2-0.10.2-0.3-0.31.4-1.72.0-1.9-1.81.9-1.6-1.7-2.21.61.8-1.81.80.81.2
Bone: cortical apparent density1.31.72.9-1.6-1.3-1.7-1.5-1.71.6-1.61.7-1.5-1.31.1-0.71.01.2-0.91.11.10.7-1.2-1.11.1-1.2-1.6-1.1
Bone: cortical area0.91.43.10.50.70.1-0.0-0.20.1-0.10.20.1-1.21.5-1.71.61.5-1.61.51.51.8-1.4-1.51.5-1.4-0.6-1.4
Bone: cortical porosity0.40.51.1-0.1-0.2-0.3-0.4-0.50.4-0.40.5-0.3-0.90.9-0.90.91.0-0.90.80.90.6-0.9-0.80.9-0.7-0.5-0.7
Bone: cortical porosity0.20.20.60.60.50.40.20.2-0.30.2-0.20.4-0.40.6-0.80.60.7-0.60.50.50.5-0.5-0.50.5-0.40.1-0.4
Bone: cortical thickness4.47.49.7-2.0-1.6-2.5-2.6-2.82.6-2.62.8-2.3-3.13.0-2.62.82.9-2.82.92.92.1-3.0-3.03.0-2.9-2.7-2.8
Bone: cortical thickness3.13.65.9-2.1-1.8-2.3-2.4-2.42.3-2.32.4-2.2-2.01.7-1.11.51.7-1.41.61.60.7-1.8-1.71.7-1.6-2.2-1.8
Bone: cortical tissue density1.01.42.4-1.5-1.2-1.5-1.4-1.51.4-1.41.6-1.3-1.11.0-0.60.81.1-0.81.01.00.6-1.1-1.01.0-1.0-1.4-1.0
Condit. Reinf. active minus inactive responses0.50.51.1-0.1-0.10.10.20.3-0.30.3-0.40.10.7-0.91.0-1.0-0.91.0-1.1-1.0-0.90.91.0-0.90.90.30.9
Condit. Reinf. active-inactive response ratio0.20.20.5-0.6-0.5-0.6-0.6-0.60.5-0.60.6-0.5-0.50.2-0.10.20.3-0.20.20.30.1-0.3-0.30.3-0.3-0.7-0.1
Condit. Reinf. active responses0.70.81.8-0.4-0.5-0.00.10.2-0.10.1-0.2-0.20.9-1.21.4-1.2-1.21.3-1.1-1.1-1.31.11.2-1.11.10.30.9
Condit. Reinf. inactive responses0.91.13.8-1.2-1.3-0.7-0.6-0.50.6-0.60.4-1.00.7-1.11.6-1.3-1.31.4-1.0-1.1-1.91.01.1-1.21.10.20.6
Incentive salience index mean2.02.43.41.00.81.31.41.5-1.51.5-1.61.21.7-1.81.6-1.7-1.81.7-1.9-1.8-1.11.81.8-1.71.81.31.7
Condit. Reinf. lever presses4.25.98.51.81.52.32.32.5-2.42.5-2.61.92.9-2.62.3-2.6-2.72.5-2.6-2.7-1.62.72.6-2.62.72.32.4
Condit. Reinf. active minus inactive responses0.40.51.30.70.60.30.20.1-0.30.2-0.10.4-0.70.8-1.11.00.9-1.00.90.81.0-0.9-0.90.9-0.8-0.5-0.9
Condit. Reinf. active-inactive response ratio0.91.12.91.21.30.80.70.5-0.70.5-0.51.0-0.91.0-1.51.31.1-1.41.01.01.7-1.0-1.11.0-1.0-0.2-0.8
Condit. Reinf. active responses0.00.00.10.20.10.20.20.2-0.30.3-0.30.10.2-0.20.1-0.2-0.20.2-0.2-0.2-0.40.20.2-0.20.3-0.1-0.1
Condit. Reinf. inactive responses0.70.92.8-0.6-0.8-0.1-0.10.00.10.1-0.1-0.41.2-1.11.4-1.3-1.21.4-1.1-1.1-1.71.11.2-1.21.30.30.8
Condit. Reinf. lever presses0.50.61.20.0-0.10.30.30.4-0.30.5-0.50.01.0-1.01.1-1.0-1.01.1-1.0-1.0-1.10.91.0-1.01.10.60.6
Condit. Reinf. lever reinforcers received0.10.10.20.30.20.40.40.4-0.40.4-0.40.30.4-0.40.3-0.4-0.40.4-0.4-0.4-0.40.40.4-0.50.40.20.1
Conditioned reinforcement - actives0.91.53.6-0.7-0.5-1.0-1.1-1.11.1-1.31.2-0.6-1.91.9-1.51.41.1-1.41.41.61.1-1.4-1.01.3-1.2-0.9-0.8
Conditioned reinforcement - inactives1.42.14.7-1.0-0.8-1.3-1.3-1.41.3-1.51.5-1.0-2.21.7-1.31.61.7-1.51.71.60.9-1.6-1.31.5-1.6-1.5-1.6
Conditioned locomotion0.10.10.40.20.30.0-0.0-0.0-0.00.00.00.2-0.40.4-0.50.50.0-0.50.50.60.2-0.4-0.10.2-0.3-0.1-0.3
Patch foraging indifference point 0 sec1.22.23.8-1.7-1.5-1.8-1.8-1.92.0-1.92.0-1.7-1.91.5-0.71.11.4-1.01.31.40.3-1.3-1.21.1-1.2-1.1-1.0
Patch foraging indifference point AUC0.60.92.80.30.40.0-0.0-0.30.1-0.20.2-0.1-0.50.9-1.41.31.1-1.31.11.01.3-1.2-1.31.1-1.0-0.6-1.7
Delay disc. indifference point, 0s delay0.30.40.90.70.80.50.70.6-0.50.5-0.40.7-0.20.9-0.70.50.6-0.60.30.41.0-0.3-0.80.7-0.3-0.5-0.6
Delay disc. indifference point, 16s delay3.63.95.4-1.7-1.6-2.0-2.2-2.22.2-2.32.2-2.0-2.11.9-1.91.91.9-1.81.91.81.0-2.2-2.31.9-2.0-2.0-1.9
Delay disc. indifference point, 2s delay0.91.03.00.70.90.40.50.3-0.30.3-0.10.8-0.91.4-1.31.21.1-1.31.11.11.7-0.9-1.41.4-1.0-0.5-0.8
Delay disc. indifference point, 24s delay0.60.61.3-0.6-0.6-0.7-1.0-1.10.9-0.80.9-0.7-0.80.6-0.70.80.9-0.80.50.50.6-0.9-1.11.0-0.7-0.3-0.8
Delay disc. indifference point, 4s delay1.51.64.41.01.20.50.70.3-0.50.2-0.20.9-1.21.5-2.01.61.4-1.61.31.42.1-1.3-1.81.5-1.3-0.8-1.3
Delay disc. indifference point, 8s delay0.30.41.3-0.2-0.1-0.3-0.3-0.30.4-0.50.4-0.3-0.60.8-0.90.70.9-0.70.60.50.7-0.7-1.10.8-0.6-0.8-0.6
Indifference point function ln k0.50.82.00.80.60.80.80.9-0.91.1-0.90.70.7-0.80.7-0.9-0.70.8-1.0-0.9-0.50.91.0-0.81.01.01.4
Indifference point function log k0.50.82.00.80.60.80.80.9-0.91.1-0.90.70.7-0.80.7-0.9-0.70.8-1.0-0.9-0.50.91.0-0.81.01.01.4
Patch foraging total patch changes 0 sec1.52.94.9-1.9-1.7-2.0-2.1-2.12.2-2.22.2-2.0-2.11.8-0.91.41.7-1.31.61.70.4-1.6-1.51.4-1.5-1.2-1.3
Patch foraging total patch changes 12 sec2.22.84.3-1.7-1.6-1.9-1.9-2.02.0-2.12.0-1.8-1.61.7-1.11.51.7-1.41.51.60.4-1.7-1.61.6-1.3-1.6-1.9
Patch foraging total patch changes 18 sec2.23.47.4-2.6-2.5-2.6-2.4-2.62.7-2.52.6-2.7-1.51.2-0.61.01.5-0.91.11.2-0.3-1.4-1.31.2-1.1-1.6-1.7
Patch foraging total patch changes 24 sec1.62.87.6-2.8-2.8-2.6-2.4-2.42.5-2.52.4-2.5-1.10.60.30.30.8-0.20.70.7-1.0-0.8-0.60.5-0.6-1.5-0.8
Patch foraging total patch changes 6 sec2.63.97.3-2.4-2.2-2.5-2.4-2.52.6-2.72.5-2.3-2.11.5-1.01.41.6-1.31.71.70.1-1.8-1.61.6-1.5-2.1-2.1
Patch foraging time to switch 0 sec0.30.62.0-1.4-1.4-1.3-1.2-1.01.1-1.21.1-1.1-0.40.10.4-0.10.10.20.10.2-0.7-0.10.00.1-0.2-0.8-0.1
Patch foraging water rate 0 sec0.30.61.5-0.2-0.2-0.5-0.7-0.80.5-0.50.6-0.6-1.20.9-0.91.00.9-1.00.90.80.6-1.1-1.00.8-0.7-0.7-0.8
Patch foraging water rate 12 sec0.30.61.4-1.1-1.1-1.1-1.0-1.21.0-1.01.0-1.1-0.90.30.10.3-0.0-0.20.40.3-0.5-0.5-0.3-0.0-0.3-1.2-0.6
Patch foraging water rate 18 sec0.10.10.30.40.40.3-0.00.1-0.20.1-0.20.2-0.50.2-0.40.50.3-0.50.50.40.3-0.5-0.40.2-0.5-0.1-0.2
Patch foraging water rate 24 sec1.01.42.6-0.2-0.0-0.6-0.9-0.90.7-0.80.8-0.8-1.41.0-1.61.61.5-1.61.51.31.3-1.6-1.61.5-1.3-1.0-1.4
Patch foraging water rate 6 sec0.40.61.8-1.0-1.1-1.0-1.0-1.11.0-0.91.0-1.3-0.60.4-0.30.50.7-0.40.50.5-0.2-0.7-0.60.4-0.4-1.1-0.8
Seeking ratio, delayed vs. immediate footshock0.20.20.90.50.50.30.00.2-0.30.2-0.10.5-0.50.7-0.50.60.6-0.60.70.41.0-0.5-0.40.2-0.70.30.1
Distance traveled before self-admin0.60.72.11.31.41.31.41.4-1.31.2-1.21.30.6-0.0-0.3-0.1-0.10.00.3-0.20.80.40.1-0.00.00.70.2
Distance traveled after self-admin0.60.82.21.31.51.11.00.9-0.90.7-0.81.3-0.10.7-0.80.80.5-0.91.20.71.5-0.4-0.20.4-0.90.9-0.3
Extensor digitorum longus weight0.20.71.91.21.11.31.11.2-1.01.2-1.11.11.0-0.2-0.1-0.3-0.40.2-0.5-0.40.00.50.4-0.30.41.40.4
Bone: elastic displacement0.70.81.5-1.0-0.9-1.1-1.1-1.11.1-1.21.1-0.9-1.20.8-0.70.80.9-0.70.80.90.3-0.9-0.80.8-0.9-1.0-0.7
Bone: elastic work1.72.33.8-0.4-0.2-0.8-0.8-1.00.9-1.01.1-0.6-1.91.9-1.91.91.8-1.91.91.91.6-1.8-1.91.8-1.9-1.3-1.5
Bone: endosteal estimation2.45.417.34.24.13.73.43.4-3.43.2-3.33.70.90.0-1.30.50.1-0.70.10.01.90.3-0.00.00.02.20.4
Bone: endosteal perimeter3.06.413.63.73.43.73.53.6-3.53.5-3.63.52.4-1.60.7-1.2-1.51.1-1.5-1.6-0.11.81.6-1.61.72.91.6
Epididymis fat weight8.428.951.6-6.7-6.5-7.1-7.1-7.27.1-7.17.2-6.6-6.04.2-2.53.74.3-3.43.94.00.4-4.7-4.14.4-4.0-5.7-4.0
Delta time in closed arm before/after self-admin0.40.31.0-0.2-0.2-0.3-0.3-0.40.4-0.40.4-0.4-0.40.5-0.50.70.8-0.70.80.70.3-0.7-0.50.7-0.7-0.8-1.0
Delta time in open arm before/after self-admin0.20.20.70.40.50.20.20.1-0.30.4-0.20.4-0.40.7-0.80.40.2-0.50.10.50.9-0.3-0.70.5-0.20.10.1
Diff in mean of infusions in LGA sessions1.92.45.5-1.1-1.4-0.6-0.4-0.20.4-0.30.2-0.30.6-1.82.2-2.1-1.72.1-1.9-1.8-2.31.81.9-1.62.01.02.3
Delay discount exponential model param1.31.43.90.0-0.10.40.40.6-0.50.6-0.60.31.2-1.51.8-1.5-1.51.5-1.3-1.2-1.51.52.0-1.61.31.01.3
Extinction: sum of active levers before priming0.30.41.5-0.1-0.20.10.20.2-0.10.1-0.20.20.3-0.70.7-0.8-0.60.9-0.7-0.8-0.40.80.1-0.50.61.21.2
Active lever presses in extinction session 60.50.51.5-1.1-1.2-1.0-1.0-0.91.1-1.01.0-0.9-0.60.30.10.10.30.00.1-0.0-0.5-0.3-0.30.2-0.2-0.5-0.2
Bone: final force4.47.111.3-0.6-0.3-1.3-1.6-1.81.7-1.81.9-1.2-3.13.4-3.43.33.3-3.33.33.32.8-3.2-3.33.3-3.3-2.0-3.0
Bone: final moment3.86.010.0-0.4-0.2-1.1-1.4-1.51.5-1.51.6-1.0-2.93.1-3.23.13.1-3.13.13.12.7-3.0-3.13.1-3.0-1.8-2.8
Food consumed during 24 hour testing period0.50.72.21.41.51.21.21.1-1.21.2-1.11.20.30.2-0.80.40.2-0.50.30.31.1-0.1-0.30.2-0.20.3-0.2
Glucose5.38.414.23.43.23.73.63.7-3.83.7-3.83.53.0-2.51.6-2.1-2.52.0-2.6-2.5-0.42.62.4-2.42.62.92.3
Heart weight1.11.83.80.00.2-0.4-0.8-0.80.6-0.70.7-0.2-1.51.9-1.81.81.4-1.81.81.81.9-1.6-1.81.5-1.8-0.2-0.6
Delay discount hyperbolic model param1.31.53.90.0-0.10.40.40.6-0.50.6-0.70.21.3-1.51.8-1.5-1.51.5-1.3-1.3-1.51.52.0-1.61.31.11.4
Intermittent access intake day 1-15 change0.10.10.80.20.30.20.10.1-0.30.3-0.30.10.5-0.10.3-0.2-0.90.2-0.4-0.0-0.40.20.4-0.60.2-0.0-0.3
Intermittent access intake escalation0.10.10.8-0.2-0.1-0.2-0.3-0.40.2-0.20.2-0.3-0.10.5-0.20.3-0.4-0.20.10.5-0.1-0.4-0.1-0.0-0.3-0.6-0.9
Intermittent access intake escalation 20.70.82.11.31.51.31.21.1-1.31.3-1.31.01.1-0.30.2-0.3-1.20.3-0.5-0.30.00.40.6-0.70.30.4-0.4
Intermitt. access day 1 inactive lever presses0.10.51.71.31.31.21.10.9-1.11.1-1.00.90.4-0.20.00.2-0.0-0.20.1-0.10.40.00.4-0.2-0.20.2-0.6
Intermitt. access day 15 inactive lever presses0.40.82.90.50.60.20.1-0.20.0-0.10.1-0.2-0.51.0-1.21.21.0-1.21.11.30.8-1.1-0.91.0-1.1-0.5-1.7
Intermitt. access escalation Index1.72.55.20.2-0.10.60.81.0-0.91.0-1.00.71.6-2.01.9-2.1-1.52.1-2.2-2.1-1.72.01.5-1.82.31.51.9
Intermittent access day 1 total infusions0.30.51.6-1.0-1.1-1.1-1.1-0.81.0-1.01.1-0.3-1.10.50.0-0.00.30.00.10.1-0.00.0-0.30.20.10.61.3
Intermittent access day 15 total infusions0.20.41.1-0.7-0.6-0.9-0.9-0.80.8-0.80.9-0.2-1.10.9-0.40.40.2-0.40.30.60.3-0.4-0.40.2-0.3-0.10.2
Intermittent access terminal intake (last 3 days)0.60.92.1-0.9-0.8-1.1-1.2-1.11.1-1.11.2-0.5-1.41.3-0.70.80.5-0.80.91.10.6-0.8-0.80.6-0.8-0.7-0.5
Intermittent access total infusions0.40.51.4-0.7-0.6-0.8-0.9-0.80.9-0.90.9-0.3-1.21.0-0.60.60.5-0.60.60.80.6-0.5-1.00.6-0.4-0.00.1
Intermittent access day 1 locomotion0.20.22.10.10.00.00.10.3-0.10.10.00.7-0.2-0.00.0-0.30.00.2-0.2-0.40.00.40.0-0.30.31.21.4
Intermittent access day 15 total locomotion0.40.81.90.81.00.40.30.2-0.30.1-0.20.8-0.71.2-1.21.20.6-1.31.41.21.4-1.0-0.60.8-1.1-0.1-0.8
Intermittent access total locomotion0.50.71.90.60.80.30.10.1-0.20.20.00.7-0.91.3-1.31.10.7-1.11.01.01.4-0.8-1.00.8-0.90.2-0.2
Intermittent access standard deviation1.42.94.9-0.8-0.5-1.2-1.3-1.51.3-1.51.4-0.9-2.02.2-2.02.01.4-2.02.22.21.5-2.0-1.91.6-2.1-1.9-1.8
Left kidney weight2.511.626.30.81.1-0.5-0.9-1.20.9-1.01.3-0.2-3.64.5-5.14.74.3-4.84.44.44.6-4.3-4.54.3-4.4-1.5-3.0
Right kidney weight2.611.927.91.31.80.1-0.2-0.70.4-0.50.80.6-3.44.6-5.34.74.5-4.84.54.45.1-4.1-4.44.3-4.3-1.8-3.2
Cocaine induced anxiety1.01.41.91.11.01.31.31.3-1.31.3-1.41.01.4-1.31.1-1.2-1.01.1-1.3-1.3-0.71.20.9-1.01.31.41.2
Post-drug Anxiety0.50.61.30.40.30.60.70.6-0.60.8-0.70.21.2-0.80.8-0.9-0.60.9-1.1-1.0-0.90.80.5-0.61.00.70.6
Baseline Anxiety0.70.82.9-1.6-1.7-1.4-1.3-1.31.3-1.11.2-1.5-0.30.30.3-0.2-0.10.3-0.10.1-0.9-0.1-0.10.00.1-1.0-0.3
Tail length2.18.221.44.24.43.22.92.5-2.62.6-2.23.3-0.62.5-3.72.92.6-3.22.52.44.6-2.0-2.62.6-2.31.3-1.4
Length with tail2.912.534.25.25.53.93.43.0-3.23.3-2.84.0-0.93.0-4.63.73.2-4.02.92.95.9-2.5-3.13.1-2.81.3-2.1
Length without tail2.27.222.93.13.62.11.81.5-1.71.7-1.32.4-1.62.8-3.93.33.0-3.52.62.74.8-2.5-2.82.6-2.6-0.3-2.2
Times rat made contact with spout1.01.23.8-1.9-2.0-1.6-1.6-1.41.6-1.41.4-1.7-0.2-0.20.7-0.5-0.30.6-0.2-0.2-1.50.10.2-0.30.2-0.7-0.0
Lifetime Intake0.60.82.1-0.6-0.4-0.8-0.8-0.70.9-0.91.0-0.1-1.51.5-0.90.80.9-0.80.91.11.0-0.7-1.20.9-0.7-0.2-0.0
Liver weight, left2.44.010.53.23.23.03.13.0-2.92.8-2.83.21.4-0.5-0.4-0.3-0.50.1-0.4-0.51.30.90.7-0.70.62.11.1
Liver weight, right2.23.912.23.43.52.92.72.6-2.72.6-2.43.30.50.7-1.40.90.6-1.00.50.62.4-0.1-0.40.6-0.21.70.2
Locomotor activity1.82.88.72.93.02.72.52.4-2.62.6-2.62.31.5-0.3-0.50.0-0.3-0.2-0.3-0.20.80.40.3-0.50.31.1-0.4
Locomotor testing distance0.61.12.71.61.71.61.51.4-1.51.5-1.61.11.4-0.50.1-0.3-0.40.2-0.5-0.3-0.10.50.4-0.60.50.9-0.4
Locomotor testing rearing0.40.82.51.61.61.31.41.2-1.31.4-1.31.20.7-0.1-0.50.10.1-0.2-0.1-0.00.60.1-0.10.00.10.90.0
Locomotion in novel chamber0.50.72.60.20.30.00.2-0.00.2-0.20.2-0.2-0.21.1-1.61.01.1-1.01.01.01.0-0.9-1.30.9-1.1-0.2-1.1
Locomotion in novel chamber post-restriction0.81.43.9-0.5-0.2-0.7-0.6-0.80.7-0.90.8-0.7-1.11.7-1.21.31.1-1.21.51.60.9-1.3-1.21.1-1.5-1.8-2.0
Fecal boli incidents, locomotor time 10.40.62.7-0.2-0.3-0.0-0.30.30.10.0-0.10.20.2-1.01.0-0.9-0.80.8-0.6-1.0-0.61.00.7-0.70.61.61.6
Change in fecal boli incidents, locomotor task0.30.30.70.40.50.20.1-0.2-0.10.20.00.2-0.50.9-0.50.80.5-0.80.70.70.8-0.8-0.40.5-0.7-0.2-0.6
Time >=10cm from walls, locomotor time 10.70.72.31.51.51.31.31.2-1.21.2-1.11.40.30.2-0.60.3-0.2-0.30.30.20.90.10.30.1-0.10.70.2
Bouts of movement, locomotor time 11.11.23.00.80.81.01.11.3-1.11.4-1.20.71.5-1.40.5-1.2-1.21.2-1.7-1.2-0.71.20.6-0.91.70.50.7
Total resting periods, locomotor time 10.91.01.80.91.01.11.11.3-1.11.3-1.20.91.1-1.10.2-0.9-0.90.8-1.3-0.8-0.31.00.6-0.71.20.60.7
Rest time, locomotor task time 10.60.72.41.31.51.41.31.2-1.31.1-1.31.40.7-0.4-0.0-0.1-0.60.1-0.1-0.20.50.40.4-0.30.00.2-0.4
Distance moved, locomotor task time 10.60.91.5-0.8-0.8-1.0-1.0-1.11.1-1.11.0-0.9-1.21.0-0.71.01.0-1.01.21.10.5-1.0-0.60.7-1.0-1.2-0.8
Vertical activity count, locomotor time 10.20.51.0-0.7-0.7-0.8-0.9-1.00.8-0.70.8-1.0-0.70.8-0.50.70.9-0.70.60.80.2-0.9-0.60.5-0.5-0.8-0.7
Time >=10cm from walls, locomotor time 20.30.51.61.00.90.90.80.9-0.91.0-0.81.10.5-0.2-0.2-0.2-0.20.2-0.3-0.40.40.40.5-0.30.40.91.3
Bouts of movement, locomotor time 20.81.33.71.91.91.71.81.8-1.91.9-1.71.61.2-0.6-0.3-0.1-0.1-0.1-0.4-0.30.60.30.3-0.30.2-0.1-0.2
Total resting periods, locomotor time 21.22.15.22.32.32.12.22.2-2.32.3-2.11.91.7-1.0-0.0-0.4-0.50.3-0.8-0.60.40.60.5-0.60.50.40.1
Rest time, locomotor task time 23.34.27.92.72.72.72.72.8-2.82.8-2.82.62.3-1.70.7-1.3-1.91.2-1.5-1.60.01.71.2-1.61.42.11.3
Distance moved, locomotor task time 22.52.95.2-1.8-1.8-2.0-1.8-2.02.0-2.02.1-1.6-2.11.7-1.21.52.0-1.41.51.70.5-1.7-1.21.6-1.2-2.3-1.5
Vertical activity count, locomotor time 20.60.82.1-1.2-1.2-1.2-1.2-1.51.2-1.21.2-1.2-0.90.7-0.10.50.9-0.40.40.6-0.1-0.8-0.40.5-0.3-1.2-0.5
Light reinforcement 10.20.61.3-1.0-0.8-1.0-1.1-1.01.1-1.11.1-0.9-1.00.8-0.10.60.7-0.50.50.60.2-0.7-0.50.6-0.8-0.6-0.4
Light reinforcement 20.30.52.01.01.20.90.60.6-0.70.7-0.51.0-0.40.7-0.30.60.6-0.70.40.51.4-0.5-0.50.4-0.60.3-0.0
Bone: marrow area2.45.216.94.14.03.73.43.4-3.33.2-3.23.60.90.0-1.30.50.1-0.70.10.11.90.3-0.00.1-0.02.10.4
Bone: maximum diameter1.22.36.62.62.42.42.22.3-2.22.1-2.22.31.0-0.5-0.3-0.2-0.40.1-0.5-0.50.60.70.5-0.40.51.90.7
Bone: maximum force2.95.19.3-0.00.2-0.7-1.0-1.11.0-1.21.2-0.6-2.63.0-3.12.92.9-2.92.92.92.7-2.8-2.92.8-2.8-1.6-2.6
Bone: maximum moment2.44.28.20.20.4-0.4-0.7-0.80.8-0.90.9-0.4-2.32.7-2.92.72.6-2.72.62.62.6-2.5-2.72.6-2.5-1.3-2.4
Mean time between licks in bursts1.74.28.32.72.62.82.92.7-2.82.8-2.72.72.3-1.50.9-1.2-1.21.1-1.5-1.50.21.61.4-1.41.52.21.6
Mean num. licks in bursts1.11.83.8-2.0-1.9-1.9-1.9-1.91.9-1.81.9-1.9-1.30.8-0.30.60.7-0.40.80.8-0.5-0.9-0.70.8-0.6-1.5-0.9
Cd content in liver0.40.41.3-1.0-1.1-1.0-0.9-0.80.8-1.00.9-0.6-1.00.10.40.00.10.00.20.2-0.6-0.2-0.00.1-0.2-1.0-0.1
Co content in liver2.12.43.8-1.6-1.7-1.8-1.8-1.81.8-1.91.8-1.6-1.91.3-1.01.31.3-1.21.51.50.3-1.5-1.41.3-1.6-1.8-1.3
Cu content in liver1.31.65.0-2.1-2.2-1.7-1.6-1.51.6-1.51.4-1.80.1-0.61.2-0.9-0.51.0-0.5-0.5-2.00.40.6-0.60.6-0.80.3
Fe content in liver1.31.52.4-1.1-1.1-1.3-1.5-1.51.4-1.41.4-1.3-1.61.2-0.91.21.2-1.11.11.10.3-1.4-1.21.2-1.3-1.2-1.2
K content in liver0.20.21.1-0.7-0.7-0.6-0.7-0.70.7-0.50.5-1.00.5-0.10.0-0.1-0.10.10.00.0-0.3-0.1-0.1-0.1-0.1-0.3-0.2
Mg content in liver1.31.33.30.70.61.01.01.0-1.01.1-1.10.71.8-1.31.0-1.2-1.21.2-1.2-1.3-1.11.31.2-1.21.21.41.1
Mn content in liver5.05.69.92.22.02.72.52.7-2.62.8-2.82.23.1-2.31.7-2.1-2.42.1-2.2-2.2-1.22.42.2-2.32.42.52.0
Na content in liver1.41.52.6-1.4-1.3-1.5-1.6-1.61.5-1.61.5-1.5-1.00.9-0.91.01.0-0.91.11.10.1-1.2-1.20.9-1.2-1.2-1.2
Rb content in liver0.60.72.8-0.4-0.6-0.1-0.2-0.10.10.0-0.1-0.41.1-0.91.1-1.0-0.91.1-1.0-1.0-1.70.80.9-1.01.10.70.7
Se content in liver2.73.25.82.22.12.42.32.3-2.42.4-2.42.32.0-1.50.9-1.2-1.51.1-1.3-1.3-0.41.51.3-1.41.41.71.3
Sr content in liver0.30.30.80.90.80.70.60.6-0.60.6-0.60.70.10.4-0.60.40.3-0.40.50.50.6-0.3-0.30.3-0.50.3-0.1
Zn content in liver0.10.10.30.40.20.40.40.4-0.40.5-0.40.30.6-0.40.3-0.3-0.30.3-0.3-0.3-0.40.40.4-0.30.30.50.3
Bone: minimum diameter1.73.18.62.92.92.82.72.6-2.62.6-2.62.61.2-0.5-0.3-0.2-0.50.1-0.5-0.61.00.70.5-0.60.51.80.5
Time in familiar zone, hab. session 11.51.54.3-2.0-2.1-1.7-1.4-1.41.4-1.21.3-1.60.1-0.81.5-1.1-0.71.2-0.8-0.9-1.80.60.8-0.90.8-0.60.5
Time in novel zone, hab. session 11.01.03.41.81.81.61.31.3-1.31.2-1.31.50.00.4-0.90.60.3-0.70.40.41.1-0.2-0.30.4-0.30.7-0.2
Total zone transitions, hab. session 10.30.40.9-0.4-0.3-0.10.00.10.1-0.0-0.0-0.30.6-0.80.9-0.8-0.90.9-0.8-0.8-0.90.70.8-0.80.80.20.4
Total locomotion distance, hab. session 10.20.20.6-0.6-0.5-0.4-0.2-0.20.3-0.30.2-0.50.1-0.50.8-0.6-0.60.6-0.5-0.5-0.80.50.5-0.50.60.00.3
Locomotion velocity, hab. session 10.10.20.6-0.8-0.6-0.7-0.5-0.50.6-0.60.5-0.7-0.2-0.10.4-0.2-0.20.2-0.1-0.1-0.40.10.1-0.10.1-0.3-0.0
Time in familiar zone, hab. session 20.20.20.8-0.8-0.9-0.7-0.6-0.60.7-0.70.7-0.7-0.2-0.10.4-0.20.10.20.00.0-0.50.00.1-0.00.1-0.10.1
Time in novel zone, hab. session 20.10.10.30.30.40.20.10.1-0.20.1-0.10.2-0.30.3-0.60.40.2-0.40.30.30.5-0.3-0.40.3-0.4-0.2-0.3
Total zone transitions, hab. session 20.20.30.7-0.7-0.6-0.7-0.7-0.70.6-0.70.6-0.7-0.80.20.00.20.1-0.10.20.2-0.2-0.3-0.30.3-0.2-0.7-0.4
Total locomotion distance, hab. session 20.40.62.0-0.9-0.9-0.7-0.6-0.40.5-0.60.4-0.7-0.1-0.71.2-0.9-0.80.9-0.7-0.8-1.40.60.8-0.70.8-0.20.5
Locomotion velocity, hab. session 20.50.62.1-0.9-0.8-0.6-0.5-0.30.4-0.50.3-0.60.0-0.81.2-1.0-0.91.0-0.8-0.8-1.50.80.9-0.80.9-0.10.6
Novel to familiar place preference ratio0.20.20.5-0.6-0.5-0.6-0.7-0.60.7-0.60.6-0.7-0.40.4-0.30.30.3-0.20.40.40.0-0.3-0.30.3-0.3-0.3-0.4
Novelty place preference0.20.20.3-0.4-0.3-0.4-0.6-0.50.5-0.50.5-0.5-0.50.5-0.50.40.4-0.40.50.50.3-0.4-0.40.5-0.5-0.3-0.5
Time in novel zone, NPP test0.20.20.4-0.2-0.1-0.3-0.4-0.40.4-0.40.4-0.3-0.50.6-0.60.50.5-0.50.60.50.4-0.5-0.50.5-0.5-0.3-0.5
Total zone transitions, NPP test0.50.81.9-0.4-0.3-0.10.10.2-0.10.1-0.2-0.10.7-1.11.3-1.2-1.21.2-1.2-1.2-1.41.01.1-1.11.20.30.7
Total locomotion distance, NPP test0.40.61.8-1.1-1.0-0.8-0.6-0.50.6-0.60.5-0.80.1-0.71.1-0.9-0.70.9-0.7-0.7-1.30.60.7-0.70.8-0.10.4
Locomotion velocity, NPP test0.71.03.3-1.3-1.2-0.9-0.7-0.50.7-0.60.5-1.00.3-1.01.5-1.2-1.11.3-1.0-1.1-1.81.01.1-1.01.10.00.7
Intraocular pressure0.40.51.6-0.3-0.5-0.00.10.2-0.10.1-0.10.10.6-1.00.9-1.0-0.91.0-1.0-1.0-1.00.90.9-0.50.90.41.3
Delta distance traveled before/after self-admin1.11.22.7-0.00.1-0.4-0.5-0.60.6-0.70.7-0.1-1.31.4-1.11.51.2-1.51.51.61.4-1.3-1.11.1-1.5-0.2-0.9
Delta ambulatory time before/after self-admin0.50.61.50.40.50.1-0.1-0.20.1-0.20.20.3-0.81.0-0.81.21.0-1.21.11.21.2-1.0-0.70.8-1.20.3-0.5
Parametrial fat weight0.71.54.30.10.3-0.3-0.3-0.40.5-0.50.6-0.2-0.92.1-2.01.61.5-1.61.71.61.4-1.5-1.51.5-1.6-0.5-1.3
Pavlov. Cond. lever latency3.34.27.1-2.4-2.2-2.6-2.6-2.62.7-2.62.7-2.3-2.41.9-1.21.61.9-1.41.71.80.3-1.8-1.71.8-1.7-1.9-1.7
Pavlov. Cond. magazine entry latency3.64.66.62.11.92.42.52.5-2.52.5-2.62.22.5-2.11.7-1.9-2.21.8-2.1-2.1-0.92.22.1-2.12.11.91.9
Pavlov. Cond. change in total contacts1.11.23.61.81.91.71.71.6-1.71.6-1.61.60.9-0.3-0.3-0.0-0.5-0.1-0.2-0.21.00.40.2-0.30.20.70.2
Pavlov. Cond. index score4.65.89.02.52.32.82.92.9-3.02.9-3.02.52.8-2.31.7-2.0-2.41.9-2.2-2.3-0.82.32.2-2.32.22.12.0
Pavlov. Cond. latency score4.05.18.62.62.42.82.92.8-2.92.9-2.92.52.6-2.11.4-1.7-2.11.6-1.9-2.0-0.52.11.9-2.01.92.01.8
Pavlov. Cond. lever contacts3.23.96.92.42.32.62.62.6-2.62.6-2.62.32.3-1.71.0-1.4-1.71.3-1.5-1.6-0.11.71.5-1.71.51.81.5
Pavlov. Cond. magazine entry number3.64.56.5-1.7-1.4-2.1-2.2-2.22.2-2.32.3-1.8-2.62.3-2.02.22.4-2.12.22.31.3-2.3-2.32.3-2.3-1.8-2.0
Pavlov. Cond. intertrial magazine entries1.31.64.3-2.1-2.0-2.0-1.9-1.81.9-1.91.8-1.8-1.00.40.30.10.3-0.00.40.4-0.9-0.5-0.40.3-0.3-1.2-0.7
Pavlov. Cond. lever-magazine prob. diff.4.75.88.62.42.22.72.82.8-2.92.9-2.92.42.8-2.41.8-2.1-2.52.0-2.3-2.3-0.92.42.3-2.42.32.12.1
Pavlov. Cond. response bias4.65.78.02.22.02.62.72.7-2.82.8-2.82.32.8-2.41.9-2.2-2.52.1-2.3-2.4-1.12.42.3-2.42.42.12.1
Pavlov. Cond. lever latency0.10.20.40.60.60.40.30.3-0.30.3-0.30.5-0.30.4-0.60.50.4-0.50.40.40.6-0.3-0.40.4-0.50.2-0.0
Pavlov. Cond. magazine entry latency0.20.31.10.71.00.60.70.6-0.50.5-0.40.60.20.4-0.50.40.3-0.50.30.41.1-0.2-0.30.4-0.40.2-0.3
Pavlov. Cond. change in total contacts0.20.30.5-0.3-0.3-0.5-0.5-0.50.5-0.50.5-0.5-0.40.6-0.60.50.5-0.50.50.60.4-0.6-0.60.6-0.5-0.6-0.7
Pavlov. Cond. index score0.00.10.20.20.40.30.40.3-0.30.3-0.20.30.4-0.00.0-0.1-0.10.0-0.1-0.00.40.10.1-0.10.1-0.0-0.1
Pavlov. Cond. latency score0.00.00.30.00.20.00.20.0-0.00.10.00.00.10.3-0.20.20.2-0.20.20.20.5-0.2-0.20.2-0.2-0.2-0.4
Pavlov. Cond. lever contacts0.10.10.3-0.5-0.5-0.4-0.3-0.30.3-0.30.3-0.50.2-0.20.4-0.3-0.20.3-0.2-0.2-0.30.10.2-0.20.3-0.3-0.2
Pavlov. Cond. magazine entry number0.20.20.9-0.3-0.5-0.2-0.3-0.20.1-0.10.0-0.20.2-0.60.5-0.5-0.40.5-0.5-0.6-0.90.40.5-0.50.50.20.6
Pavlov. Cond. intertrial magazine entries1.72.63.31.20.91.51.61.6-1.61.7-1.71.51.8-1.81.5-1.7-1.61.6-1.8-1.8-1.21.81.8-1.71.81.51.7
Pavlov. Cond. lever-magazine prob. diff.0.00.10.20.20.40.30.40.3-0.30.3-0.20.20.4-0.10.1-0.1-0.10.1-0.2-0.10.30.20.1-0.10.10.1-0.1
Pavlov. Cond. response bias0.10.20.40.20.30.40.50.4-0.40.4-0.40.30.6-0.50.5-0.5-0.50.5-0.5-0.5-0.20.50.5-0.50.50.30.2
Time in closed arm before self-admin0.10.10.40.00.00.1-0.20.1-0.10.1-0.2-0.10.50.00.0-0.3-0.60.3-0.5-0.5-0.30.30.2-0.40.40.20.4
Time in closed arm after self-admin1.31.42.0-1.0-0.9-1.1-1.2-1.21.2-1.31.3-1.3-0.81.3-1.11.21.2-1.11.31.10.4-1.4-1.11.3-1.3-1.4-1.2
Time in open arm before self-admin0.60.61.40.60.50.71.00.9-0.70.7-0.70.80.7-1.20.7-0.8-0.30.8-0.8-0.7-0.50.90.8-0.70.81.01.0
Time in open arm after self-admin0.80.91.81.01.01.01.31.1-1.11.3-1.11.30.6-0.60.3-0.7-0.80.7-0.9-0.50.11.00.4-0.60.91.31.2
Bone: periosteal estimation1.32.78.02.82.82.32.01.9-2.01.8-1.82.3-0.20.9-1.81.31.0-1.41.00.92.2-0.7-0.90.9-0.90.9-0.6
Bone: periosteal perimeter1.01.75.32.32.32.12.01.9-1.91.8-1.82.00.70.0-0.70.30.1-0.40.10.11.10.1-0.10.00.01.20.1
Bone: post-yield work2.63.87.02.52.52.62.62.6-2.62.6-2.62.42.1-1.50.8-1.2-1.41.1-1.5-1.5-0.21.61.4-1.51.52.21.2
Progressive ratio test 1 active lever presses0.40.51.7-0.8-0.8-1.0-1.0-0.81.0-0.91.1-0.3-1.31.0-0.40.40.8-0.50.40.60.4-0.4-0.60.4-0.20.10.7
Progressive ratio test 1 breakpoint0.50.61.8-0.8-0.8-1.0-1.0-0.81.0-0.91.1-0.3-1.41.1-0.50.50.8-0.50.40.60.5-0.4-0.70.4-0.30.10.7
Progressive ratio test 1 inactive lever presses1.11.53.6-1.7-1.7-1.8-1.9-1.81.8-1.71.8-1.5-1.50.8-0.20.70.8-0.60.70.9-0.3-0.9-0.40.7-0.5-1.0-0.9
Progressive ratio test 2 active lever presses0.30.31.0-1.0-1.0-1.0-0.9-0.80.8-1.00.9-0.5-0.80.40.1-0.1-0.10.1-0.00.1-0.2-0.0-0.2-0.20.2-0.20.4
Progressive ratio test 2 breakpoint0.30.41.1-1.0-1.0-1.1-1.0-0.90.9-1.00.9-0.6-0.80.40.1-0.0-0.00.00.10.2-0.2-0.1-0.3-0.10.1-0.30.3
Progressive ratio test 2 inactive lever presses0.20.31.30.10.2-0.1-0.2-0.00.2-0.40.20.4-0.91.1-0.80.60.6-0.70.70.70.8-0.4-0.40.5-0.60.20.0
Incentive Sensitization - Responses0.20.30.9-0.5-0.4-0.3-0.2-0.10.1-0.30.0-0.00.1-0.70.9-0.7-0.90.8-0.4-0.5-0.70.60.5-0.90.6-0.10.4
Incentive Sensitization - Breakpoint0.20.30.9-0.5-0.5-0.3-0.2-0.10.1-0.40.1-0.10.1-0.70.9-0.7-1.00.8-0.4-0.5-0.80.60.5-0.90.5-0.20.3
Sum of active levers in priming session hrs 5-60.40.30.90.1-0.00.30.40.3-0.40.2-0.40.50.2-0.60.8-0.8-0.60.7-0.5-0.7-0.50.70.7-0.80.30.91.0
Progressive ratio3.35.210.1-0.20.1-0.9-1.0-1.01.1-1.41.4-0.3-2.73.2-3.02.93.0-3.03.22.82.7-2.7-2.52.9-2.8-2.0-2.2
Food seeking constrained by brief footshock0.00.00.1-0.2-0.2-0.2-0.2-0.10.2-0.10.1-0.20.3-0.3-0.1-0.2-0.20.2-0.1-0.3-0.20.2-0.10.10.20.10.0
Seeking ratio, punishment vs. effort2.94.29.20.0-0.40.60.70.7-0.81.1-1.10.12.6-3.02.7-2.6-2.72.7-2.8-2.6-2.62.42.3-2.52.51.81.9
Retroperitoneal fat weight0.31.33.40.00.2-0.4-0.3-0.40.5-0.50.6-0.1-1.11.8-1.61.41.5-1.51.41.61.3-1.3-1.31.6-1.2-0.8-1.2
Reaction time number correct1.01.93.9-1.7-1.7-1.8-1.8-1.91.8-1.71.8-2.0-1.30.7-0.70.91.1-0.81.00.8-0.1-1.2-1.11.1-1.0-1.6-1.2
Reaction time mean minus median2.56.213.03.53.43.53.63.6-3.63.5-3.53.52.5-1.60.6-1.4-1.51.2-1.7-1.40.31.91.6-1.51.62.41.4
Reaction time mean minus median AUC1.74.49.42.82.62.83.12.9-3.02.9-2.92.82.3-1.70.7-1.4-1.41.2-1.6-1.4-0.11.61.5-1.51.51.61.0
Reaction time num false alarms0.20.20.80.50.70.30.40.3-0.30.4-0.20.2-0.20.7-0.60.50.3-0.60.30.40.9-0.4-0.40.6-0.3-0.4-0.7
Reaction time num false alarms AUC0.20.41.40.50.70.40.40.3-0.30.3-0.20.3-0.40.9-0.80.70.5-0.80.50.71.2-0.6-0.60.8-0.5-0.4-0.7
Reaction time trials correct on left1.01.93.9-1.7-1.7-1.8-1.8-1.91.8-1.71.8-2.0-1.30.7-0.70.91.1-0.81.00.8-0.1-1.2-1.11.1-1.0-1.6-1.2
Reaction time trials on left0.91.73.4-1.6-1.6-1.7-1.7-1.81.7-1.61.7-1.8-1.30.7-0.70.91.1-0.81.00.8-0.1-1.2-1.11.1-1.0-1.5-1.2
Reaction time mean3.96.312.03.13.13.33.53.4-3.43.3-3.33.22.7-2.01.3-1.7-1.81.5-1.9-1.8-0.02.22.0-2.01.82.51.8
Reaction time mean AUC4.06.412.53.13.23.33.53.4-3.53.3-3.43.32.7-2.01.3-1.7-1.91.5-1.9-1.80.02.22.0-2.01.82.41.7
Median of all reaction times2.83.97.32.32.42.62.72.6-2.62.5-2.62.42.2-1.61.2-1.4-1.51.3-1.4-1.5-0.01.81.6-1.71.42.01.5
Reaction time omissions2.84.18.12.72.52.72.82.7-2.82.7-2.72.81.7-1.40.7-1.3-1.21.1-1.6-1.40.11.71.4-1.11.52.31.9
Reaction time false alarm rate0.60.82.81.51.71.41.41.4-1.31.3-1.21.40.40.3-0.30.1-0.2-0.2-0.20.11.10.30.10.10.20.60.2
Reaction time premature initiation rate1.01.43.0-0.00.1-0.4-0.6-0.60.6-0.60.7-0.3-0.91.4-1.71.61.6-1.61.51.71.6-1.4-1.51.6-1.6-0.7-1.1
Reaction time premature initiations1.83.34.9-1.0-0.9-1.4-1.6-1.61.6-1.51.7-1.4-1.71.9-2.12.02.1-2.02.12.21.5-2.1-2.12.2-2.1-1.7-1.7
Std. dev. reaction times3.56.414.33.63.63.63.83.7-3.73.6-3.53.72.3-1.50.6-1.3-1.31.0-1.6-1.30.61.81.5-1.41.62.41.6
Reaction time trials completed0.91.73.4-1.6-1.6-1.7-1.7-1.81.7-1.61.7-1.8-1.30.7-0.70.91.1-0.81.00.8-0.1-1.2-1.11.1-1.0-1.5-1.2
Reaction time trials AUC0.91.73.5-1.6-1.7-1.7-1.8-1.91.7-1.61.7-1.9-1.20.6-0.60.81.0-0.70.90.8-0.2-1.1-1.01.0-0.9-1.4-1.1
Run reversals in cocaine runway, females0.70.71.8-1.2-1.2-1.1-1.1-1.01.3-1.41.2-1.0-1.10.7-0.40.40.7-0.30.90.7-0.0-0.5-0.90.5-0.7-0.40.0
Run reversals in cocaine runway, males2.02.06.12.42.52.22.22.1-2.02.0-1.92.20.5-0.2-0.70.20.5-0.40.2-0.11.60.2-0.40.3-0.01.20.9
Latency to leave start box in cocaine runway0.10.10.7-0.0-0.10.0-0.1-0.0-0.10.1-0.1-0.10.5-0.40.5-0.4-0.50.4-0.6-0.3-0.50.30.8-0.70.40.20.4
Latency to leave start box in cocaine runway, F0.40.51.30.10.00.30.20.1-0.40.4-0.4-0.21.2-1.00.8-0.8-0.70.8-0.9-0.8-0.90.71.0-1.00.80.70.6
Latency to leave start box in cocaine runway, M0.40.41.0-0.1-0.0-0.3-0.4-0.30.3-0.50.40.1-0.81.0-0.70.90.5-0.90.60.90.7-0.8-0.30.5-0.9-0.9-0.6
Std. dev. time between licks in bursts2.43.37.02.62.52.62.62.5-2.52.6-2.52.51.8-1.20.5-0.8-0.90.7-1.2-1.20.41.21.1-1.11.12.01.2
Total sessions with >9 infusions0.60.71.7-0.6-0.4-0.8-0.7-0.70.8-0.80.9-0.3-1.21.3-1.00.91.0-0.91.11.10.8-0.8-1.00.6-0.9-0.8-0.7
Short access day 1 total inactive lever presses1.01.44.51.51.81.11.00.9-1.00.9-0.81.2-0.40.8-1.61.21.0-1.31.11.22.1-0.8-1.11.1-1.0-0.2-1.0
Short access day 10 total inactive lever presses0.10.20.80.10.00.20.10.2-0.20.1-0.40.10.3-0.90.9-0.5-0.50.5-0.5-0.5-0.70.60.8-0.60.40.40.2
Short access day 1 total infusions0.10.10.6-0.4-0.3-0.4-0.2-0.20.3-0.30.40.1-0.60.6-0.20.10.3-0.10.30.30.4-0.0-0.70.2-0.0-0.30.1
Short access day 10 total infusions0.50.71.4-0.7-0.5-0.9-0.8-0.80.9-1.00.9-0.4-1.21.2-0.90.80.6-0.81.01.10.6-0.7-0.80.7-0.8-0.8-0.8
Short access total infusions0.81.02.7-0.7-0.5-0.9-0.9-0.91.0-1.01.1-0.3-1.61.6-1.11.01.2-1.01.11.21.1-0.9-1.31.1-0.8-0.5-0.3
Short access day 1 locomotion0.50.71.8-0.5-0.5-0.20.10.10.00.0-0.10.20.5-0.81.3-1.2-1.21.2-0.9-0.8-1.21.11.0-1.31.10.20.7
Short access day 10 total locomotion0.20.51.51.11.21.01.00.8-1.00.9-0.90.90.50.3-0.50.2-0.3-0.30.20.30.5-0.1-0.0-0.4-0.2-0.4-0.7
Short access total locomotion0.10.10.30.30.50.30.30.3-0.30.3-0.30.50.20.3-0.2-0.0-0.30.00.10.20.10.1-0.1-0.4-0.00.10.1
One hour access (0.3 mA shock)0.80.94.0-0.4-0.5-0.2-0.20.10.1-0.10.00.20.2-0.61.3-1.2-1.21.2-1.0-0.9-1.11.21.1-1.31.31.22.0
Compulsive drug intake3.54.28.20.70.41.21.31.5-1.31.4-1.51.02.2-2.62.5-2.4-1.92.4-2.4-2.5-2.02.52.5-2.32.42.62.9
One hour access (shock baseline)0.40.62.1-0.5-0.2-0.6-0.8-0.70.7-0.80.8-0.1-1.31.5-0.90.80.6-0.80.81.11.0-0.7-1.10.7-0.6-0.5-0.2
Social response proportion0.20.30.90.80.90.70.80.8-0.80.8-0.70.90.0-0.2-0.1-0.0-0.2-0.0-0.2-0.20.30.20.10.10.30.10.0
Social responses0.10.10.40.30.40.10.10.1-0.1-0.0-0.00.3-0.50.4-0.60.50.3-0.50.40.40.5-0.4-0.40.6-0.4-0.4-0.5
Social time2.73.78.42.82.92.82.92.8-2.82.7-2.72.61.9-1.10.2-0.8-1.20.7-1.0-1.00.61.30.9-1.01.21.81.1
Soleus weight1.95.513.53.73.63.63.43.4-3.33.4-3.33.42.0-0.8-0.1-0.6-0.90.4-1.0-0.91.01.31.0-0.90.92.91.1
Bone: stiffness0.91.42.3-0.6-0.5-0.8-1.0-1.00.9-1.01.0-0.8-1.41.4-1.31.41.4-1.31.41.41.0-1.4-1.41.3-1.3-1.0-1.5
Tibialis anterior weight0.62.14.3-1.8-1.9-1.8-2.1-2.02.0-1.91.9-2.0-1.31.2-0.81.01.0-0.81.01.1-0.2-1.2-1.11.1-1.0-1.1-1.3
Time to tail flick, vehicle, before self-admin1.01.12.40.40.40.60.81.1-0.80.8-0.90.51.5-1.21.1-1.2-1.11.2-1.4-1.2-1.21.21.3-1.51.30.40.4
Time to tail flick, vehicle, after self-admin1.01.42.31.00.91.21.31.5-1.31.3-1.41.11.3-0.90.7-1.2-1.31.1-1.2-1.3-0.71.30.9-1.11.31.11.2
Time to tail flick, test, before self-admin0.00.00.2-0.0-0.10.00.1-0.00.0-0.0-0.10.10.3-0.00.1-0.2-0.10.2-0.20.1-0.40.20.2-0.30.20.2-0.3
Time to tail flick, test, after self-admin0.80.81.40.70.71.01.11.0-1.01.1-1.00.81.2-1.01.0-0.9-0.50.9-1.0-1.1-0.50.91.0-0.80.70.40.5
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.4-0.4-0.3-0.3-0.30.3-0.30.3-0.3-0.40.20.1-0.1-0.20.10.1-0.2-0.1-0.0-0.30.3-0.00.10.5
Delta time to tail flick, test, before/after SA0.20.20.7-0.6-0.5-0.4-0.3-0.20.2-0.20.2-0.50.1-0.60.7-0.5-0.40.5-0.4-0.8-0.80.30.6-0.40.3-0.80.2
Tibia length1.33.510.23.03.22.42.32.0-2.22.0-1.92.5-0.11.3-2.21.51.2-1.71.21.22.8-0.9-1.31.2-1.10.6-0.7
Ambulatory time before self-admin0.20.30.80.70.90.70.80.8-0.70.6-0.60.70.10.3-0.50.10.2-0.20.50.10.90.0-0.30.3-0.2-0.1-0.3
Ambulatory time after self-admin0.80.93.21.21.40.90.80.8-0.70.6-0.61.2-0.50.9-1.01.00.9-1.11.30.91.8-0.6-0.70.7-1.11.1-0.1
Bone: tissue strength2.82.85.90.00.1-0.5-0.7-0.80.8-0.80.9-0.5-1.72.1-2.42.32.1-2.22.12.12.0-2.1-2.22.1-2.2-0.8-1.8
Total heroin consumption0.30.42.30.70.70.70.60.7-0.70.6-0.61.00.1-0.20.3-0.2-0.10.1-0.1-0.30.40.40.5-0.4-0.01.50.7
Bone: trabecular number0.61.03.0-1.6-1.7-1.3-1.2-1.01.2-1.01.0-1.40.2-0.61.2-0.9-0.71.0-0.5-0.6-1.70.50.7-0.70.7-0.30.2
Bone: trabecular spacing1.52.05.81.51.51.00.80.6-0.70.6-0.51.1-0.91.5-2.21.81.6-1.91.51.62.4-1.4-1.61.6-1.6-0.0-0.9
Bone: trabecular thickness0.50.61.4-1.1-1.1-0.8-0.5-0.60.6-0.50.5-0.80.3-0.71.2-0.9-0.70.9-0.7-0.7-1.20.60.7-0.80.8-0.30.3
Bone: trabecular tissue density0.91.43.20.10.3-0.3-0.2-0.50.3-0.40.50.0-1.31.5-1.51.51.4-1.61.51.51.8-1.4-1.51.4-1.5-1.2-1.4
Water consumed over 24 hours0.00.10.20.40.40.40.30.4-0.30.4-0.40.20.5-0.0-0.2-0.1-0.20.1-0.0-0.00.10.10.0-0.10.10.3-0.0
Number of responses in last shaping day0.30.31.10.40.50.20.30.1-0.10.3-0.00.5-0.71.0-0.90.60.8-0.70.40.71.0-0.4-0.90.7-0.5-0.1-0.3