Hub : Genes

Zfp133

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Zfp133	0.14	0.06	1.8e-15	0.14	0.13	0.14	0.01	1.6e-15	1.4e-14	6.9e-15	1.1e-02
2	Brain	gene expression	Zfp133	0.16	0.09	1.6e-12	0.15	0.14	0.15	0.08	1.6e-13	7.7e-13	8.2e-14	5.5e-08
3	NAcc	gene expression	Zfp133	0.09	0.05	1.7e-09	0.08	0.09	0.09	0.09	7.6e-10	2.2e-10	2.0e-10	1.6e-10
4	LHb	gene expression	Zfp133	0.24	0.16	1.4e-03	0.05	0.04	0.01	0.06	2.6e-02	3.3e-02	1.4e-01	2.0e-02
5	Adipose	gene expression	Zfp133	0.16	0.08	9.2e-15	0.08	0.12	0.12	0.12	8.7e-09	5.4e-13	5.7e-13	6.8e-13
6	BLA	gene expression	Zfp133	0.06	0.04	5.8e-03	0.03	0.02	0.02	0.04	6.7e-03	3.1e-02	3.9e-02	5.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
Bone: apparent density	0.1	0.1	0.2	-0.4	-0.2	0.2	0.2	0.3	0.4
Area under the delay curve	1.3	1.3	4.1	-1.3	-0.9	1.0	0.3	2.0	0.6
BMI with tail	7.5	24.2	29.2	5.2	5.2	-5.2	-5.4	-3.5	-4.8
BMI without tail	6.4	13.1	15.5	3.8	3.8	-3.9	-3.7	-3.4	-3.0
Body weight	8.9	37.3	46.3	6.8	6.4	-6.3	-6.5	-5.2	-5.4
Weight adjusted by age	0.1	0.1	0.5	0.2	0.1	-0.1	-0.2	-0.7	0.3
Bone surface	0.3	0.5	0.9	0.6	0.7	-0.8	-0.6	-0.9	-0.6
Bone volume	0.1	0.2	0.6	0.2	0.3	-0.4	-0.2	-0.8	0.1
Breakpoint value in progressive ratio session	0.5	0.5	0.9	0.7	0.7	-0.8	-0.6	-0.9	-0.5
Number of licking bursts	0.1	0.1	0.4	0.0	0.2	-0.1	-0.3	0.6	-0.1
Context. condit. distance diff. score	0.1	0.1	0.1	0.2	0.3	-0.3	-0.2	-0.4	-0.1
Locomotion velocity, session 1	1.1	1.2	1.8	-1.3	-1.1	1.0	1.3	-0.2	1.2
Locomotion distance, session 1	4.4	5.6	6.5	-2.5	-2.6	2.5	2.5	1.6	2.3
Locomotion velocity, session 2	2.5	3.0	3.6	-1.9	-1.8	1.9	1.6	1.8	1.2
Locomotion distance, session 2	4.7	6.6	8.9	-2.7	-2.7	2.6	2.8	0.9	3.0
Locomotion velocity, session 3	3.2	3.8	4.6	-2.2	-2.0	2.0	2.1	1.6	1.8
Locomotion distance, session 3	1.4	1.5	1.8	-1.3	-1.2	1.2	1.2	1.4	1.0
Stereotopy head waving bouts, day 3	0.1	0.1	0.3	0.3	0.1	-0.1	-0.0	-0.6	-0.0
Stereotopy head waving duration, day 3	0.2	0.2	0.5	0.4	0.4	-0.4	-0.3	-0.7	-0.3
Locomotion velocity, session 7	1.0	1.1	1.5	-0.9	-1.2	1.2	1.2	0.3	1.2
Locomotion distance, session 7	0.2	0.3	0.7	-0.1	-0.5	0.5	0.5	-0.5	0.8
Stereotopy head waving bouts, day 7	0.1	0.1	0.1	0.3	0.3	-0.4	-0.3	-0.3	-0.3
Stereotopy head waving duration, day 7	0.1	0.1	0.3	-0.6	-0.3	0.3	0.3	0.5	0.1
Locomotion velocity, session 8	0.9	1.1	1.7	-1.0	-1.1	1.1	1.2	-0.2	1.3
Locomotion distance, session 8	2.2	3.3	4.7	-1.8	-2.0	1.9	2.0	0.6	2.2
Degree of sensitization distance	0.8	0.8	2.6	1.1	0.6	-0.7	-0.7	-1.6	-0.2
Degree of sensitization stereotypy	0.3	0.4	0.5	0.5	0.7	-0.7	-0.7	-0.2	-0.7
Conditioned locomotion	0.3	0.4	0.7	-0.6	-0.4	0.3	0.6	-0.8	0.8
Cocaine response after cond. corrected	1.4	1.6	2.6	-1.0	-1.4	1.3	1.4	0.4	1.6
Cocaine response after cond. not corrected	2.6	2.9	4.5	-1.5	-1.9	1.8	1.8	0.7	2.1
Cocaine response before conditioning	0.2	0.3	0.4	-0.7	-0.5	0.5	0.4	0.5	0.5
Saline control response	1.6	2.0	7.7	1.4	1.0	-1.1	-0.8	-2.8	-0.1
Bone: connectivity density	0.2	0.3	0.6	-0.8	-0.5	0.5	0.6	0.5	0.4
Bone: cortical apparent density	0.3	0.4	1.6	-0.5	-0.3	0.4	0.2	1.3	-0.3
Bone: cortical area	0.2	0.3	0.5	0.6	0.5	-0.4	-0.7	-0.1	-0.7
Bone: cortical porosity	0.4	0.4	0.6	0.6	0.7	-0.8	-0.7	-0.5	-0.7
Bone: cortical porosity	0.7	0.8	1.0	0.8	0.9	-0.9	-1.0	-0.6	-0.9
Bone: cortical thickness	0.2	0.4	1.1	0.0	0.3	-0.2	-0.6	0.8	-1.1
Bone: cortical thickness	1.4	1.6	2.7	-1.4	-1.3	1.3	0.9	1.7	0.7
Bone: cortical tissue density	0.2	0.3	1.1	-0.4	-0.2	0.3	0.2	1.1	-0.3
Condit. Reinf. active minus inactive responses	0.0	0.0	0.1	-0.1	0.0	-0.0	-0.0	0.2	0.2
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	-0.2	-0.1	0.1	0.0	0.3	0.3
Condit. Reinf. active responses	0.1	0.1	0.1	-0.3	-0.2	0.2	0.2	0.4	0.4
Condit. Reinf. inactive responses	0.0	0.0	0.1	0.1	-0.1	0.1	0.1	-0.3	0.1
Incentive salience index mean	0.5	0.7	2.1	-0.8	-0.6	0.7	0.4	1.4	0.4
Condit. Reinf. lever presses	0.7	0.9	4.4	-0.7	-0.4	0.6	0.1	2.1	-0.3
Condit. Reinf. active minus inactive responses	1.4	1.8	3.5	1.3	1.3	-1.4	-1.1	-1.9	-0.9
Condit. Reinf. active-inactive response ratio	1.5	1.6	2.0	1.2	1.3	-1.4	-1.2	-1.4	-1.0
Condit. Reinf. active responses	0.7	1.0	1.2	1.0	1.0	-1.0	-1.0	-0.8	-1.1
Condit. Reinf. inactive responses	0.1	0.2	0.5	0.1	0.1	0.0	-0.2	0.7	-0.7
Condit. Reinf. lever presses	3.7	5.0	5.8	2.3	2.4	-2.4	-2.2	-2.2	-1.9
Condit. Reinf. lever reinforcers received	1.0	1.5	1.6	1.2	1.3	-1.3	-1.2	-1.1	-1.3
Conditioned reinforcement - actives	0.9	0.9	1.7	-0.7	-1.0	0.9	1.0	-0.4	1.3
Conditioned reinforcement - inactives	1.4	1.6	3.3	-0.8	-1.2	1.1	1.6	-0.5	1.8
Conditioned locomotion	0.5	0.6	1.1	-1.0	-0.7	0.6	0.8	0.7	0.5
Patch foraging indifference point 0 sec	0.5	0.7	2.2	-0.2	-0.3	0.3	0.9	-1.5	1.1
Patch foraging indifference point AUC	0.6	0.7	1.2	-0.9	-0.9	0.8	0.8	1.1	0.6
Delay disc. indifference point, 0s delay	0.4	0.4	0.9	0.2	0.5	-0.5	-0.9	0.6	-0.8
Delay disc. indifference point, 16s delay	2.5	2.5	4.0	-1.7	-1.5	1.6	1.1	2.0	1.3
Delay disc. indifference point, 2s delay	0.5	0.6	1.5	0.2	0.6	-0.5	-1.2	0.8	-0.9
Delay disc. indifference point, 24s delay	5.9	5.7	8.2	-2.6	-2.4	2.4	2.0	2.9	2.0
Delay disc. indifference point, 4s delay	0.2	0.2	0.7	0.2	0.2	-0.1	-0.8	0.8	-0.3
Delay disc. indifference point, 8s delay	1.9	2.0	3.3	-1.7	-1.4	1.3	0.9	1.8	1.1
Indifference point function ln k	0.2	0.2	0.9	-0.0	-0.2	0.2	0.3	-0.9	0.6
Indifference point function log k	0.2	0.2	0.9	-0.0	-0.2	0.2	0.3	-0.9	0.6
Patch foraging total patch changes 0 sec	0.5	0.8	1.5	-0.5	-0.5	0.4	1.0	-1.2	1.2
Patch foraging total patch changes 12 sec	0.2	0.2	0.3	0.5	0.4	-0.5	-0.5	-0.5	-0.5
Patch foraging total patch changes 18 sec	0.8	1.0	1.7	-0.9	-1.0	0.9	1.3	0.0	1.3
Patch foraging total patch changes 24 sec	0.1	0.1	0.2	-0.1	-0.2	0.2	0.3	-0.1	0.4
Patch foraging total patch changes 6 sec	0.1	0.1	0.4	-0.2	-0.2	0.1	0.5	-0.3	0.7
Patch foraging time to switch 0 sec	1.6	2.5	3.6	1.9	1.6	-1.5	-1.7	-0.7	-1.8
Patch foraging water rate 0 sec	2.2	3.5	4.9	-2.2	-1.9	1.8	1.9	1.3	1.9
Patch foraging water rate 12 sec	3.7	5.7	6.6	-2.5	-2.4	2.5	2.3	2.6	2.0
Patch foraging water rate 18 sec	10.0	13.4	16.0	-3.8	-4.0	4.0	3.7	2.3	4.0
Patch foraging water rate 24 sec	3.4	4.7	6.7	-2.4	-2.3	2.2	2.1	1.0	2.6
Patch foraging water rate 6 sec	4.7	6.9	7.8	-2.7	-2.8	2.8	2.7	1.9	2.7
Seeking ratio, delayed vs. immediate footshock	0.3	0.4	0.7	0.8	0.5	-0.6	-0.3	-0.8	-0.6
Distance traveled before self-admin	0.2	0.2	0.3	0.5	0.3	-0.3	-0.5	0.1	-0.6
Distance traveled after self-admin	0.3	0.3	1.2	-0.6	0.0	-0.1	0.0	1.1	-0.7
Extensor digitorum longus weight	0.2	0.6	1.3	1.0	0.6	-0.7	-0.7	-1.1	-0.3
Bone: elastic displacement	0.2	0.2	0.8	0.4	0.4	-0.4	-0.5	0.0	-0.9
Bone: elastic work	2.4	3.0	4.5	1.7	1.8	-1.8	-2.0	-0.7	-2.1
Bone: endosteal estimation	2.1	4.5	7.7	2.5	2.0	-2.1	-2.0	-2.8	-1.0
Bone: endosteal perimeter	0.6	1.2	4.0	1.1	0.8	-0.9	-0.7	-2.0	0.1
Epididymis fat weight	6.0	14.0	17.1	4.1	3.9	-3.8	-4.0	-3.3	-3.2
Delta time in closed arm before/after self-admin	0.2	0.2	0.5	-0.4	-0.3	0.3	0.7	0.0	0.4
Delta time in open arm before/after self-admin	2.0	2.0	2.4	1.3	1.5	-1.6	-1.5	-1.0	-1.4
Diff in mean of infusions in LGA sessions	0.3	0.4	1.2	-0.4	-0.5	0.6	0.4	1.1	0.1
Delay discount exponential model param	1.6	1.6	4.5	1.4	1.1	-1.2	-0.4	-2.1	-0.8
Extinction: sum of active levers before priming	0.1	0.1	0.2	-0.1	-0.3	0.2	0.5	-0.4	0.5
Active lever presses in extinction session 6	1.6	1.6	4.3	1.3	1.0	-1.2	-0.9	-2.1	-0.5
Bone: final force	0.5	0.8	1.4	1.0	0.9	-0.9	-1.2	-0.4	-0.9
Bone: final moment	0.4	0.7	1.2	0.9	0.9	-0.8	-1.1	-0.4	-0.8
Food consumed during 24 hour testing period	0.1	0.1	0.3	0.5	0.2	0.0	-0.4	-0.1	-0.0
Glucose	0.8	1.2	3.0	1.2	0.9	-0.9	-0.8	-1.7	-0.4
Heart weight	2.6	3.7	4.2	2.0	2.0	-2.0	-2.0	-2.0	-1.5
Delay discount hyperbolic model param	1.0	1.1	3.6	1.1	0.8	-0.9	-0.1	-1.9	-0.5
Intermittent access intake day 1-15 change	1.2	1.1	3.1	1.2	0.8	-0.9	-0.6	-1.8	-0.6
Intermittent access intake escalation	0.6	0.6	2.1	0.9	0.5	-0.6	-0.4	-1.5	-0.3
Intermittent access intake escalation 2	1.2	1.2	2.8	1.2	0.9	-1.0	-0.8	-1.7	-0.5
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.2	-0.0	-0.3	0.4	0.3	0.2	0.1
Intermitt. access day 15 inactive lever presses	1.2	1.3	4.6	1.4	0.7	-0.7	-0.2	-2.1	-0.2
Intermitt. access escalation Index	2.5	2.2	4.2	1.4	1.5	-1.6	-1.1	-2.1	-1.0
Intermittent access day 1 total infusions	0.0	0.0	0.1	0.1	-0.1	-0.1	-0.4	-0.1	-0.2
Intermittent access day 15 total infusions	0.6	0.6	1.8	0.9	0.4	-0.7	-0.6	-1.4	-0.4
Intermittent access terminal intake (last 3 days)	0.6	0.7	1.4	1.0	0.5	-0.7	-0.7	-1.2	-0.7
Intermittent access total infusions	0.5	0.6	1.4	0.8	0.5	-0.8	-0.7	-1.2	-0.5
Intermittent access day 1 locomotion	0.2	0.2	0.6	-0.3	-0.2	0.0	-0.2	0.8	-0.4
Intermittent access day 15 total locomotion	0.1	0.1	0.2	0.2	0.3	-0.5	-0.4	-0.4	-0.3
Intermittent access total locomotion	0.1	0.1	0.3	-0.3	-0.3	0.1	-0.1	0.6	-0.1
Intermittent access standard deviation	0.1	0.1	0.3	-0.2	-0.4	0.2	0.4	-0.5	0.4
Left kidney weight	1.5	4.2	5.1	2.3	2.1	-2.0	-2.2	-2.0	-1.7
Right kidney weight	1.4	4.0	6.1	2.5	2.0	-1.9	-1.9	-2.0	-1.5
Cocaine induced anxiety	0.4	0.4	0.8	-0.5	-0.7	0.7	0.7	-0.5	0.9
Post-drug Anxiety	1.5	1.7	3.3	1.6	1.2	-1.2	-1.1	-1.8	-0.7
Baseline Anxiety	3.4	3.6	4.4	2.1	2.0	-2.1	-1.8	-1.7	-1.7
Tail length	0.5	1.6	4.3	1.5	1.1	-1.1	-0.8	-2.1	-0.3
Length with tail	1.6	5.7	8.7	2.7	2.3	-2.4	-2.3	-2.9	-1.5
Length without tail	1.3	2.8	3.5	1.8	1.7	-1.6	-1.9	-1.4	-1.6
Times rat made contact with spout	3.4	3.9	4.4	2.0	2.1	-2.1	-2.0	-1.9	-1.8
Lifetime Intake	0.3	0.4	1.2	0.6	0.4	-0.7	-0.4	-1.1	-0.3
Liver weight, left	0.0	0.0	0.1	0.3	0.2	-0.2	-0.1	-0.2	-0.2
Liver weight, right	0.0	0.0	0.0	0.1	-0.2	0.1	-0.1	0.2	0.1
Locomotor activity	0.2	0.3	0.4	0.5	0.5	-0.6	-0.6	-0.5	-0.5
Locomotor testing distance	0.1	0.1	0.2	-0.4	-0.3	0.3	0.3	0.2	0.3
Locomotor testing rearing	0.2	0.2	0.5	0.3	0.6	-0.7	-0.4	-0.4	-0.3
Locomotion in novel chamber	0.9	1.1	2.2	-1.0	-0.9	0.8	1.2	-0.5	1.5
Locomotion in novel chamber post-restriction	1.7	2.1	2.9	-1.6	-1.5	1.4	1.5	0.9	1.7
Fecal boli incidents, locomotor time 1	1.5	1.6	3.3	-1.1	-1.4	1.4	1.2	-0.0	1.8
Change in fecal boli incidents, locomotor task	0.0	0.0	0.1	-0.1	0.1	-0.2	0.2	0.0	-0.3
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.3	-0.5	-0.5	0.5	0.5	0.3	0.5
Bouts of movement, locomotor time 1	2.0	2.2	3.5	-1.2	-1.7	1.6	1.5	0.8	1.9
Total resting periods, locomotor time 1	2.8	3.0	4.6	-1.4	-2.0	1.9	1.9	0.8	2.1
Rest time, locomotor task time 1	0.7	0.8	1.7	-0.4	-0.9	0.9	1.0	0.1	1.3
Distance moved, locomotor task time 1	1.1	1.2	4.3	-1.1	-0.8	0.9	0.4	2.1	-0.2
Vertical activity count, locomotor time 1	0.5	0.5	1.0	0.6	0.8	-0.6	-1.0	0.2	-0.9
Time >=10cm from walls, locomotor time 2	1.8	1.9	2.3	1.4	1.4	-1.5	-1.5	-1.3	-1.2
Bouts of movement, locomotor time 2	0.2	0.2	0.4	0.3	0.4	-0.4	-0.7	-0.2	-0.5
Total resting periods, locomotor time 2	0.2	0.2	0.4	0.4	0.4	-0.4	-0.7	-0.4	-0.5
Rest time, locomotor task time 2	0.1	0.1	0.2	-0.0	-0.3	0.3	0.4	-0.2	0.5
Distance moved, locomotor task time 2	0.8	0.9	2.3	-1.0	-0.9	0.9	0.7	1.5	0.4
Vertical activity count, locomotor time 2	0.1	0.1	0.4	-0.1	0.2	-0.1	-0.3	0.7	-0.3
Light reinforcement 1	0.2	0.3	1.0	-0.1	-0.3	0.3	0.3	-0.9	1.0
Light reinforcement 2	0.5	0.7	2.9	-0.2	-0.3	0.1	0.4	-1.7	1.0
Bone: marrow area	2.1	4.5	8.0	2.5	2.0	-2.0	-1.9	-2.8	-0.9
Bone: maximum diameter	0.8	1.6	2.8	1.5	1.1	-1.2	-1.1	-1.7	-0.6
Bone: maximum force	0.4	0.6	1.0	1.0	0.8	-0.7	-1.0	-0.5	-0.6
Bone: maximum moment	0.3	0.5	0.8	0.9	0.7	-0.7	-0.9	-0.4	-0.6
Mean time between licks in bursts	0.2	0.3	0.5	-0.7	-0.5	0.5	0.6	0.4	0.7
Mean num. licks in bursts	0.9	1.1	2.6	1.1	0.9	-0.9	-0.7	-1.6	-0.8
Cd content in liver	0.5	0.6	0.9	0.7	0.9	-0.7	-1.0	0.3	-0.8
Co content in liver	0.9	1.0	1.7	-1.3	-1.0	0.9	0.8	1.3	0.6
Cu content in liver	0.4	0.5	0.8	-0.5	-0.8	0.8	0.8	0.3	0.9
Fe content in liver	0.5	0.6	0.9	0.8	1.0	-0.8	-0.8	-0.7	-0.7
K content in liver	2.4	2.3	6.2	-1.8	-1.3	1.4	1.0	2.5	0.3
Mg content in liver	0.4	0.4	1.6	-0.7	-0.2	0.3	0.1	1.3	-0.4
Mn content in liver	1.6	1.8	2.7	-1.7	-1.4	1.2	1.5	0.2	1.6
Na content in liver	0.6	0.6	1.8	-0.4	0.3	-0.3	-0.4	1.3	-1.2
Rb content in liver	0.2	0.2	1.4	-0.1	-0.1	0.2	-0.1	1.2	-0.2
Se content in liver	0.1	0.2	0.7	-0.1	0.1	0.0	-0.2	0.8	-0.4
Sr content in liver	0.6	0.5	1.1	-0.6	-0.7	0.7	0.8	0.0	1.0
Zn content in liver	0.1	0.1	0.4	-0.3	-0.2	0.4	0.3	0.7	0.2
Bone: minimum diameter	0.7	1.3	1.6	1.3	1.1	-1.1	-1.1	-1.2	-1.0
Time in familiar zone, hab. session 1	0.4	0.4	0.8	0.4	0.4	-0.4	-0.5	0.9	-0.9
Time in novel zone, hab. session 1	0.3	0.3	1.6	0.2	0.3	-0.3	-0.2	-1.3	0.3
Total zone transitions, hab. session 1	1.1	1.6	1.9	-1.3	-1.3	1.4	1.4	0.9	1.1
Total locomotion distance, hab. session 1	1.9	2.7	3.5	-1.6	-1.8	1.9	1.7	1.2	1.5
Locomotion velocity, hab. session 1	2.4	3.4	4.3	-1.9	-2.0	2.1	1.9	1.5	1.6
Time in familiar zone, hab. session 2	0.1	0.1	0.3	-0.3	-0.3	0.3	0.6	-0.2	0.5
Time in novel zone, hab. session 2	0.8	0.8	1.1	0.9	0.9	-0.9	-1.0	-0.8	-0.8
Total zone transitions, hab. session 2	0.2	0.2	0.5	-0.2	-0.3	0.2	0.3	-0.7	0.7
Total locomotion distance, hab. session 2	0.7	1.0	2.0	-0.8	-0.9	0.7	1.0	-1.0	1.4
Locomotion velocity, hab. session 2	1.2	1.6	2.8	-1.3	-1.3	1.1	1.4	-0.4	1.7
Novel to familiar place preference ratio	0.1	0.1	0.2	0.4	0.4	-0.4	-0.3	-0.2	-0.2
Novelty place preference	0.1	0.1	0.2	0.4	0.4	-0.4	-0.4	0.0	-0.3
Time in novel zone, NPP test	0.5	0.5	0.6	0.8	0.8	-0.8	-0.7	-0.4	-0.5
Total zone transitions, NPP test	0.8	1.1	1.4	-1.1	-1.1	1.1	1.1	0.5	1.2
Total locomotion distance, NPP test	1.5	2.1	3.5	-1.5	-1.5	1.4	1.6	-0.0	1.9
Locomotion velocity, NPP test	2.0	2.9	4.2	-1.8	-1.8	1.7	1.9	0.4	2.1
Intraocular pressure	1.7	2.3	5.1	-1.2	-1.6	1.6	1.6	0.2	2.2
Delta distance traveled before/after self-admin	0.4	0.4	1.3	-0.6	0.3	-0.3	-0.2	1.2	-0.8
Delta ambulatory time before/after self-admin	0.2	0.2	0.8	-0.7	0.1	-0.2	-0.0	0.9	-0.4
Parametrial fat weight	13.2	25.6	29.3	5.4	5.3	-5.2	-5.2	-4.4	-4.8
Pavlov. Cond. lever latency	2.3	2.9	9.3	1.8	1.4	-1.5	-0.9	-3.1	-0.4
Pavlov. Cond. magazine entry latency	0.3	0.3	1.5	-0.3	0.1	-0.1	-0.2	1.2	-0.7
Pavlov. Cond. change in total contacts	2.8	3.0	10.7	-1.6	-1.3	1.5	0.9	3.3	0.4
Pavlov. Cond. index score	1.3	1.7	7.3	-1.2	-0.7	0.8	0.3	2.7	-0.3
Pavlov. Cond. latency score	2.0	2.5	9.0	-1.7	-1.1	1.2	0.7	3.0	0.1
Pavlov. Cond. lever contacts	1.3	1.5	6.0	-1.1	-0.8	0.9	0.4	2.5	-0.1
Pavlov. Cond. magazine entry number	0.4	0.5	1.5	-0.1	-0.4	0.2	0.6	-1.2	0.9
Pavlov. Cond. intertrial magazine entries	1.0	1.2	2.6	-0.3	-0.7	0.5	1.1	-1.6	1.6
Pavlov. Cond. lever-magazine prob. diff.	1.3	1.6	7.6	-1.0	-0.6	0.7	0.2	2.8	-0.5
Pavlov. Cond. response bias	0.6	0.7	3.8	-0.3	-0.1	0.3	-0.2	1.9	-0.7
Pavlov. Cond. lever latency	5.3	7.1	8.9	-3.0	-2.8	2.7	2.8	2.1	2.4
Pavlov. Cond. magazine entry latency	2.9	3.3	7.9	2.1	1.7	-1.7	-1.4	-2.8	-0.6
Pavlov. Cond. change in total contacts	5.7	7.8	9.1	3.0	2.9	-2.9	-2.9	-2.1	-2.8
Pavlov. Cond. index score	6.1	7.9	10.0	3.2	2.9	-2.8	-2.8	-2.7	-2.3
Pavlov. Cond. latency score	4.6	5.7	7.4	2.7	2.5	-2.4	-2.4	-2.2	-2.0
Pavlov. Cond. lever contacts	4.4	6.0	7.9	2.8	2.6	-2.5	-2.6	-2.0	-2.2
Pavlov. Cond. magazine entry number	4.1	5.0	7.1	-2.6	-2.2	2.2	2.1	2.7	1.5
Pavlov. Cond. intertrial magazine entries	1.5	1.9	3.5	-1.7	-1.3	1.2	1.1	1.9	0.8
Pavlov. Cond. lever-magazine prob. diff.	6.4	8.2	10.4	3.2	3.0	-2.9	-2.9	-2.5	-2.5
Pavlov. Cond. response bias	4.9	6.7	8.9	3.0	2.6	-2.6	-2.6	-2.7	-1.9
Time in closed arm before self-admin	0.2	0.2	0.3	-0.1	-0.5	0.5	0.5	-0.5	0.5
Time in closed arm after self-admin	0.8	0.8	1.6	-0.6	-1.0	0.9	1.3	-0.4	0.9
Time in open arm before self-admin	0.3	0.3	0.6	0.1	0.6	-0.6	-0.5	0.4	-0.8
Time in open arm after self-admin	2.2	2.5	4.2	1.2	1.7	-1.8	-1.7	-0.3	-2.0
Bone: periosteal estimation	1.2	2.5	3.8	1.9	1.5	-1.5	-1.6	-1.9	-0.9
Bone: periosteal perimeter	0.4	0.6	1.7	0.7	0.7	-0.8	-0.6	-1.3	-0.2
Bone: post-yield work	0.0	0.1	0.2	0.4	0.1	-0.1	0.0	-0.4	0.2
Progressive ratio test 1 active lever presses	0.1	0.1	0.2	0.5	0.2	-0.4	-0.4	-0.3	-0.4
Progressive ratio test 1 breakpoint	0.3	0.3	0.6	0.7	0.5	-0.5	-0.6	-0.3	-0.8
Progressive ratio test 1 inactive lever presses	0.3	0.3	1.2	0.5	0.1	-0.3	-0.0	-1.1	0.4
Progressive ratio test 2 active lever presses	0.0	0.0	0.1	0.3	0.1	-0.2	-0.3	-0.3	-0.1
Progressive ratio test 2 breakpoint	0.1	0.1	0.1	0.3	0.2	-0.3	-0.3	-0.3	-0.2
Progressive ratio test 2 inactive lever presses	0.9	1.0	3.9	0.8	0.6	-0.9	-0.5	-2.0	0.2
Incentive Sensitization - Responses	0.1	0.1	0.5	0.0	0.2	-0.3	-0.0	-0.7	0.3
Incentive Sensitization - Breakpoint	0.2	0.2	0.7	0.2	0.3	-0.5	-0.1	-0.8	0.1
Sum of active levers in priming session hrs 5-6	1.3	1.3	1.8	-0.8	-1.3	1.2	1.3	0.3	1.3
Progressive ratio	1.5	1.7	2.9	-1.3	-1.4	1.3	1.6	0.2	1.7
Food seeking constrained by brief footshock	1.7	2.1	4.2	-1.6	-1.4	1.4	1.3	2.1	0.6
Seeking ratio, punishment vs. effort	1.1	1.4	3.2	0.9	1.1	-1.1	-1.3	0.6	-1.8
Retroperitoneal fat weight	13.3	43.7	52.4	7.2	6.9	-6.8	-7.2	-4.9	-6.3
Reaction time number correct	1.3	1.9	4.2	-1.5	-1.3	1.3	1.3	-0.0	2.0
Reaction time mean minus median	3.0	3.9	5.1	2.2	2.0	-2.1	-1.8	-1.9	-1.8
Reaction time mean minus median AUC	2.8	3.6	4.3	2.0	1.9	-2.0	-1.7	-2.1	-1.5
Reaction time num false alarms	2.5	3.4	4.4	-2.1	-2.0	2.0	1.9	1.1	1.9
Reaction time num false alarms AUC	2.1	2.9	3.9	-2.0	-1.8	1.8	1.7	1.1	1.7
Reaction time trials correct on left	1.3	1.9	4.2	-1.5	-1.3	1.3	1.3	-0.0	2.0
Reaction time trials on left	1.2	1.8	4.0	-1.4	-1.2	1.2	1.2	-0.1	2.0
Reaction time mean	4.5	6.2	8.3	2.9	2.6	-2.5	-2.4	-2.3	-2.2
Reaction time mean AUC	3.6	4.9	6.2	2.5	2.3	-2.3	-2.2	-2.0	-2.0
Median of all reaction times	3.7	5.1	6.7	2.6	2.3	-2.3	-2.3	-2.0	-2.0
Reaction time omissions	1.2	1.6	2.1	1.4	1.4	-1.5	-1.1	-1.4	-0.9
Reaction time false alarm rate	0.6	0.9	1.2	-1.1	-1.0	1.0	1.0	0.9	0.7
Reaction time premature initiation rate	0.1	0.1	0.2	-0.1	-0.3	0.3	0.2	-0.3	0.4
Reaction time premature initiations	0.7	1.0	2.3	-0.9	-1.1	1.0	1.0	-0.2	1.5
Std. dev. reaction times	3.3	4.6	6.4	2.5	2.2	-2.2	-2.0	-2.0	-1.9
Reaction time trials completed	1.2	1.8	4.0	-1.4	-1.2	1.2	1.2	-0.1	2.0
Reaction time trials AUC	1.3	1.8	4.5	-1.3	-1.2	1.2	1.2	-0.4	2.1
Run reversals in cocaine runway, females	2.6	2.5	3.4	1.3	1.8	-1.8	-1.7	-1.2	-1.5
Run reversals in cocaine runway, males	2.2	2.1	3.6	1.5	1.4	-1.4	-1.7	0.0	-1.9
Latency to leave start box in cocaine runway	0.5	0.6	1.0	-0.8	-0.6	0.5	0.8	-0.7	1.0
Latency to leave start box in cocaine runway, F	0.3	0.3	1.6	0.2	0.0	-0.1	0.0	-1.2	0.6
Latency to leave start box in cocaine runway, M	0.8	0.8	1.9	-1.4	-0.8	0.7	1.1	0.6	0.5
Std. dev. time between licks in bursts	1.0	1.2	1.5	-1.2	-1.1	1.1	1.0	1.1	1.1
Total sessions with >9 infusions	1.0	1.1	1.7	1.0	1.1	-1.3	-1.0	-0.9	-0.9
Short access day 1 total inactive lever presses	0.8	0.9	2.2	-0.5	-0.7	0.5	0.8	-1.3	1.5
Short access day 10 total inactive lever presses	0.5	0.5	1.6	0.7	0.7	-0.6	-0.5	-1.2	-0.2
Short access day 1 total infusions	0.4	0.4	1.0	-0.5	-0.6	0.4	0.7	-0.5	1.0
Short access day 10 total infusions	0.1	0.1	0.3	0.2	0.1	-0.3	-0.3	-0.6	-0.2
Short access total infusions	0.4	0.4	0.7	0.5	0.6	-0.8	-0.5	-0.9	-0.4
Short access day 1 locomotion	0.4	0.5	0.9	0.4	0.7	-1.0	-0.6	-0.6	-0.6
Short access day 10 total locomotion	0.6	0.7	0.9	-0.8	-1.0	0.9	0.5	1.0	0.8
Short access total locomotion	0.1	0.2	0.5	-0.3	0.1	-0.3	-0.3	0.7	-0.4
One hour access (0.3 mA shock)	0.3	0.3	0.5	-0.5	-0.6	0.5	0.7	0.1	0.6
Compulsive drug intake	1.1	1.1	2.8	-0.8	-0.9	1.0	1.7	0.5	1.0
One hour access (shock baseline)	0.3	0.3	0.8	0.5	0.4	-0.6	-0.9	-0.3	-0.6
Social response proportion	4.6	4.9	6.3	2.0	2.5	-2.5	-2.2	-1.7	-2.4
Social responses	0.1	0.2	0.6	0.3	0.4	-0.4	-0.7	-0.2	-0.4
Social time	1.0	1.4	2.4	0.8	1.3	-1.2	-1.5	-0.6	-1.2
Soleus weight	0.0	0.1	0.2	0.5	0.4	-0.3	-0.3	-0.5	-0.0
Bone: stiffness	0.1	0.2	0.3	0.6	0.3	-0.3	-0.5	-0.6	0.0
Tibialis anterior weight	1.0	3.5	4.6	2.2	2.0	-2.0	-2.0	-1.3	-1.7
Time to tail flick, vehicle, before self-admin	2.5	2.6	8.0	1.7	1.3	-1.4	-0.8	-2.8	-0.6
Time to tail flick, vehicle, after self-admin	0.7	0.8	1.6	-0.4	-1.0	1.2	0.7	0.9	0.7
Time to tail flick, test, before self-admin	0.3	0.3	0.5	-0.1	-0.7	0.6	0.6	0.4	0.6
Time to tail flick, test, after self-admin	0.8	0.8	2.0	-0.1	-0.5	0.5	0.8	-1.4	1.2
Delta time to tail flick, vehicle, before/after SA	2.6	2.5	4.1	-1.3	-1.6	1.9	1.2	2.0	1.3
Delta time to tail flick, test, before/after SA	0.3	0.3	1.1	-0.2	-0.0	0.1	0.4	-1.0	0.6
Tibia length	2.4	6.7	8.3	2.9	2.6	-2.6	-2.8	-2.1	-2.6
Ambulatory time before self-admin	0.3	0.3	0.5	0.7	0.5	-0.5	-0.7	-0.2	-0.6
Ambulatory time after self-admin	0.3	0.4	1.4	-0.6	0.0	-0.1	-0.0	1.2	-0.6
Bone: tissue strength	1.4	1.3	1.7	1.1	1.3	-1.3	-1.3	-0.5	-1.2
Total heroin consumption	0.6	0.7	1.6	-0.6	-0.6	0.4	0.9	-1.0	1.2
Bone: trabecular number	0.3	0.5	0.8	-0.9	-0.6	0.7	0.7	0.7	0.5
Bone: trabecular spacing	1.5	1.9	3.3	1.8	1.3	-1.2	-1.4	-0.8	-1.5
Bone: trabecular thickness	0.1	0.1	0.3	-0.6	-0.4	0.4	0.2	0.4	0.2
Bone: trabecular tissue density	0.6	0.9	1.6	0.8	0.9	-0.8	-1.1	0.5	-1.3
Water consumed over 24 hours	0.3	0.4	1.9	0.5	0.4	-0.4	-0.2	-1.4	0.2
Number of responses in last shaping day	0.2	0.3	0.7	-0.1	-0.4	0.4	0.6	-0.4	0.8