Hub : Genes

Zfp133

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Zfp133 0.14 0.06 1.1e-16 0.16 0.14 0.16 0.02 5.4e-17 9.3e-15 7.0e-17 3.3e-03
2 Brain gene expression Zfp133 0.16 0.08 4.0e-12 0.14 0.12 0.15 0.1 3.0e-13 1.1e-11 9.0e-14 2.5e-09
3 IC gene expression Zfp133 0.07 0.05 9.6e-03 0.04 0.03 0.04 0.04 9.8e-03 1.5e-02 9.7e-03 1.2e-02
4 NAcc gene expression Zfp133 0.07 0.04 1.3e-10 0.06 0.06 0.07 0.04 1.3e-09 4.2e-09 2.0e-10 4.2e-06
5 LHb gene expression Zfp133 0.17 0.13 8.1e-03 0.03 0.02 -0.01 0.03 6.4e-02 1.0e-01 6.1e-01 7.6e-02
6 Adipose gene expression Zfp133 0.16 0.08 5.1e-15 0.07 0.12 0.12 0.12 1.7e-08 3.7e-13 4.5e-13 2.9e-13
7 pVTA gene expression Zfp133 0.07 0.04 4.6e-06 0.06 0.05 0.05 0.05 1.2e-05 1.2e-04 3.5e-05 4.7e-05
8 LHb isoform ratio NM_001024313.1 0.17 0.11 3.6e-03 0.09 0.04 0.02 0.06 3.1e-03 3.2e-02 1.1e-01 1.4e-02
9 LHb isoform ratio XM_063284386.1 0.18 0.11 2.3e-03 0.1 0.05 0.06 0.07 2.0e-03 2.7e-02 1.9e-02 9.8e-03
10 Liver alternative TSS NM_001024313.1 0.04 0.04 2.5e-03 0.01 0.02 0.03 0.01 4.9e-02 6.1e-03 6.1e-04 2.1e-02
11 Liver alternative TSS XM_063284386.1 0.04 0.04 2.8e-03 0.02 0.01 0.03 0.01 4.3e-03 7.7e-03 6.0e-04 2.1e-02
12 BLA gene expression Zfp133 0.05 0.04 9.4e-03 0.03 0.01 0.04 -0 7.1e-03 7.6e-02 3.1e-03 3.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.52.60.40.10.20.3-0.00.90.10.3-0.3-1.61.6-0.4
Area under the delay curve1.61.95.11.41.10.81.1-0.32.20.50.1-0.1-2.22.21.4
BMI with tail8.128.139.3-6.3-6.1-6.2-6.0-6.2-4.6-5.8-5.75.72.4-2.2-4.2
BMI without tail6.720.331.7-5.3-5.4-5.4-5.3-5.6-4.0-4.9-4.54.51.7-1.6-3.3
Body weight9.340.561.8-7.9-7.4-7.4-7.0-7.1-6.1-6.7-6.46.43.6-3.4-5.1
Weight adjusted by age0.10.20.50.40.40.40.50.30.00.70.7-0.70.0-0.10.3
Bone surface0.20.40.7-0.7-0.8-0.7-0.8-0.7-0.5-0.6-0.50.5-0.30.4-0.6
Bone volume0.10.10.4-0.3-0.4-0.2-0.3-0.3-0.1-0.10.1-0.1-0.60.6-0.2
Breakpoint value in progressive ratio session0.30.41.0-0.6-0.8-0.6-1.0-0.4-0.9-0.5-0.60.60.4-0.4-0.0
Number of licking bursts0.20.41.5-0.1-0.2-0.3-0.1-0.50.6-0.4-0.40.4-1.21.2-0.5
Context. condit. distance diff. score0.10.10.4-0.2-0.3-0.2-0.3-0.0-0.6-0.0-0.10.10.2-0.3-0.3
Locomotion velocity, session 11.41.54.81.31.21.40.91.40.21.41.1-1.10.8-0.82.2
Locomotion distance, session 13.74.77.52.52.62.52.52.32.12.32.1-2.1-0.20.12.7
Locomotion velocity, session 22.02.45.11.81.91.61.91.32.31.21.2-1.2-0.30.32.0
Locomotion distance, session 24.66.49.52.72.82.92.72.91.62.92.9-2.9-0.30.23.1
Locomotion velocity, session 32.73.14.62.12.02.02.01.91.81.81.8-1.8-0.70.61.7
Locomotion distance, session 31.01.12.11.31.21.11.21.01.40.91.0-1.0-0.70.70.9
Stereotopy head waving bouts, day 30.10.20.9-0.20.10.10.00.2-0.40.20.2-0.20.9-0.90.1
Stereotopy head waving duration, day 30.20.20.7-0.4-0.3-0.2-0.3-0.1-0.7-0.1-0.10.10.8-0.9-0.1
Locomotion velocity, session 71.51.72.71.01.31.31.51.30.61.21.3-1.31.6-1.71.2
Locomotion distance, session 70.70.93.80.10.50.50.70.6-0.10.60.7-0.71.9-2.00.9
Stereotopy head waving bouts, day 70.10.10.2-0.3-0.2-0.4-0.2-0.50.1-0.5-0.30.30.2-0.2-0.4
Stereotopy head waving duration, day 70.10.10.20.50.40.30.30.20.40.20.4-0.4-0.30.30.0
Locomotion velocity, session 81.11.43.51.01.11.21.01.3-0.01.31.1-1.11.0-1.11.9
Locomotion distance, session 82.13.14.81.81.92.01.92.10.72.12.0-2.00.3-0.42.2
Degree of sensitization distance1.31.45.9-1.1-0.7-0.6-0.5-0.5-1.4-0.3-0.30.32.4-2.40.1
Degree of sensitization stereotypy0.30.30.5-0.5-0.6-0.7-0.7-0.7-0.3-0.7-0.40.4-0.20.2-0.6
Conditioned locomotion0.40.51.20.30.20.40.10.6-0.70.70.7-0.71.1-1.10.7
Cocaine response after cond. corrected1.31.62.41.01.41.41.61.50.71.41.5-1.50.4-0.51.4
Cocaine response after cond. not corrected2.22.64.21.51.91.92.11.81.01.81.9-1.9-0.0-0.11.6
Cocaine response before conditioning0.20.20.60.60.50.50.50.20.30.40.1-0.1-0.70.7-0.1
Saline control response1.01.45.9-1.1-0.8-0.6-0.7-0.2-2.40.10.5-0.51.9-1.90.5
Bone: connectivity density0.40.62.80.70.40.50.40.30.80.30.4-0.4-1.61.7-0.3
Bone: cortical apparent density0.30.51.50.70.40.40.40.20.90.20.1-0.1-1.21.2-0.8
Bone: cortical area0.20.31.0-0.5-0.4-0.6-0.4-1.00.2-0.6-0.60.6-0.60.7-0.5
Bone: cortical porosity0.30.41.0-0.4-0.5-0.6-0.7-0.7-0.1-0.5-0.40.4-0.91.00.0
Bone: cortical porosity0.50.51.0-0.7-0.8-0.8-0.9-1.0-0.5-0.7-0.60.6-0.80.9-0.1
Bone: cortical thickness0.71.24.90.0-0.3-0.5-0.4-1.10.8-0.7-0.80.8-2.12.2-1.0
Bone: cortical thickness0.80.92.81.21.10.81.20.21.70.60.6-0.6-1.01.00.7
Bone: cortical tissue density0.30.41.10.70.40.40.40.30.80.20.1-0.1-1.01.0-0.8
Condit. Reinf. active minus inactive responses0.20.21.20.0-0.00.00.00.10.20.10.1-0.1-1.11.1-0.4
Condit. Reinf. active-inactive response ratio0.20.31.40.10.10.20.20.20.30.20.1-0.1-1.21.2-0.2
Condit. Reinf. active responses0.10.20.60.20.20.20.30.30.50.20.4-0.4-0.80.8-0.1
Condit. Reinf. inactive responses0.20.31.5-0.10.10.00.10.1-0.10.00.3-0.31.2-1.20.2
Incentive salience index mean0.60.82.50.80.60.50.70.31.50.20.4-0.4-1.61.60.0
Condit. Reinf. lever presses0.60.94.90.70.60.20.6-0.32.2-0.40.1-0.1-1.51.5-0.2
Condit. Reinf. active minus inactive responses1.41.84.1-1.5-1.4-1.2-1.5-0.9-2.0-0.9-0.80.81.8-1.7-0.8
Condit. Reinf. active-inactive response ratio1.01.22.2-1.2-1.3-1.2-1.4-0.9-1.5-0.9-0.90.90.9-0.9-0.7
Condit. Reinf. active responses0.81.21.7-1.1-1.2-1.1-1.3-1.1-1.2-1.1-1.01.00.8-0.8-1.2
Condit. Reinf. inactive responses0.20.20.8-0.2-0.2-0.4-0.4-0.60.4-0.7-0.50.5-0.40.4-0.9
Condit. Reinf. lever presses2.94.06.6-2.2-2.5-2.3-2.6-1.9-2.4-1.9-1.81.81.0-0.9-1.9
Condit. Reinf. lever reinforcers received1.11.52.4-1.3-1.4-1.2-1.6-1.1-1.4-1.2-1.11.10.9-0.9-1.3
Conditioned reinforcement - actives1.22.03.70.51.01.21.01.6-0.91.71.5-1.51.8-1.91.6
Conditioned reinforcement - inactives1.62.34.80.71.01.51.12.2-1.32.01.3-1.31.8-1.91.3
Conditioned locomotion0.30.40.91.00.70.80.50.70.50.80.2-0.2-0.80.80.4
Patch foraging indifference point 0 sec0.71.33.90.00.40.70.41.4-1.31.11.0-1.01.9-2.00.7
Patch foraging indifference point AUC0.91.33.31.31.11.00.90.71.60.70.6-0.6-1.81.80.4
Delay disc. indifference point, 0s delay0.70.71.5-0.1-0.4-0.7-0.5-1.20.9-0.9-1.11.1-1.11.1-0.0
Delay disc. indifference point, 16s delay1.92.14.41.61.41.21.40.62.11.01.0-1.0-2.02.01.5
Delay disc. indifference point, 2s delay0.70.72.6-0.2-0.5-0.7-0.5-1.60.9-0.9-0.90.9-1.01.0-0.1
Delay disc. indifference point, 24s delay4.04.57.92.52.52.22.61.32.81.91.6-1.6-1.71.72.5
Delay disc. indifference point, 4s delay0.60.62.2-0.0-0.1-0.5-0.0-1.51.2-0.7-0.70.7-1.01.00.6
Delay disc. indifference point, 8s delay1.61.94.01.71.31.21.10.41.71.10.6-0.6-2.02.01.5
Indifference point function ln k0.50.84.0-0.10.00.20.10.3-1.10.50.1-0.12.0-2.00.3
Indifference point function log k0.50.84.0-0.10.00.20.10.3-1.10.50.1-0.12.0-2.00.3
Patch foraging total patch changes 0 sec0.71.22.50.30.60.90.61.6-1.01.31.1-1.11.5-1.50.9
Patch foraging total patch changes 12 sec0.10.10.3-0.3-0.1-0.3-0.1-0.4-0.2-0.2-0.30.30.6-0.60.3
Patch foraging total patch changes 18 sec0.81.33.01.01.21.31.21.70.11.51.4-1.4-0.0-0.10.6
Patch foraging total patch changes 24 sec0.10.20.40.20.30.30.30.50.20.30.6-0.6-0.60.50.7
Patch foraging total patch changes 6 sec0.20.20.90.30.40.50.51.0-0.00.60.6-0.60.3-0.30.3
Patch foraging time to switch 0 sec1.12.33.6-1.9-1.6-1.9-1.4-1.9-0.9-1.9-1.61.60.7-0.6-1.5
Patch foraging water rate 0 sec1.42.84.42.11.82.01.72.01.51.91.6-1.6-1.11.11.4
Patch foraging water rate 12 sec2.34.87.52.52.42.22.41.82.71.81.6-1.6-2.62.61.5
Patch foraging water rate 18 sec7.611.716.83.73.93.84.13.62.93.73.8-3.8-1.00.93.9
Patch foraging water rate 24 sec3.14.46.22.32.42.42.42.41.22.52.3-2.3-0.30.22.4
Patch foraging water rate 6 sec3.95.77.62.72.72.72.62.52.12.52.5-2.5-1.41.32.3
Seeking ratio, delayed vs. immediate footshock0.40.51.4-0.9-0.6-0.4-0.6-0.1-1.2-0.4-0.20.21.1-1.1-0.2
Distance traveled before self-admin0.30.41.0-0.5-0.4-0.6-0.2-1.00.6-0.8-0.80.8-0.10.1-0.5
Distance traveled after self-admin0.70.83.31.00.40.50.20.11.10.30.2-0.2-1.81.8-0.3
Extensor digitorum longus weight0.10.30.9-0.9-0.5-0.5-0.5-0.3-0.7-0.10.1-0.10.7-0.70.0
Bone: elastic displacement0.40.40.9-0.5-0.6-0.8-0.7-0.7-0.1-0.9-0.80.80.6-0.6-0.3
Bone: elastic work2.43.15.4-1.8-1.9-2.1-2.0-2.3-0.8-2.2-2.12.10.5-0.5-1.3
Bone: endosteal estimation2.04.39.8-2.6-2.0-1.9-1.8-1.6-2.6-1.3-1.31.33.1-3.1-0.2
Bone: endosteal perimeter0.40.82.7-1.1-0.8-0.5-0.6-0.3-1.6-0.10.1-0.11.3-1.30.4
Epididymis fat weight8.027.537.5-6.1-6.0-5.8-5.8-5.5-5.5-5.2-5.25.23.9-3.7-4.3
Delta time in closed arm before/after self-admin0.20.20.40.50.40.60.50.70.30.60.2-0.2-0.20.2-0.2
Delta time in open arm before/after self-admin2.32.33.4-1.8-1.8-1.8-1.8-1.4-1.4-1.6-1.51.50.5-0.4-1.8
Diff in mean of infusions in LGA sessions0.50.61.9-0.2-0.1-0.5-0.0-0.61.4-0.9-0.90.9-0.80.9-0.6
Delay discount exponential model param1.82.05.3-1.6-1.2-1.0-1.30.2-2.3-0.7-0.30.32.2-2.1-1.5
Extinction: sum of active levers before priming0.30.31.00.40.50.60.41.0-0.00.60.5-0.50.4-0.40.6
Active lever presses in extinction session 61.91.93.0-1.5-1.5-1.2-1.6-1.2-1.7-1.0-1.31.31.5-1.5-0.8
Bone: final force0.30.51.4-0.9-0.7-0.8-0.6-1.2-0.3-0.7-0.80.80.1-0.0-0.2
Bone: final moment0.20.41.1-0.8-0.6-0.7-0.5-1.1-0.1-0.7-0.70.7-0.00.0-0.2
Food consumed during 24 hour testing period0.10.10.4-0.5-0.2-0.40.1-0.60.3-0.40.2-0.20.2-0.20.3
Glucose1.21.84.5-1.4-1.2-0.9-1.2-0.6-2.1-0.6-0.90.92.1-2.1-0.6
Heart weight1.32.03.6-1.5-1.4-1.4-1.5-1.7-1.9-0.9-1.11.11.6-1.6-0.3
Delay discount hyperbolic model param1.21.33.9-1.2-0.9-0.6-0.90.5-2.0-0.30.0-0.01.9-1.9-1.2
Intermittent access intake day 1-15 change0.81.73.3-1.5-1.2-1.0-1.1-0.8-1.8-0.9-1.31.31.7-1.6-0.8
Intermittent access intake escalation0.61.32.8-1.3-0.9-0.8-0.8-0.6-1.5-0.7-1.21.21.7-1.6-0.7
Intermittent access intake escalation 21.51.72.6-1.5-1.3-1.1-1.1-0.9-1.5-1.0-1.61.61.2-1.2-1.5
Intermitt. access day 1 inactive lever presses0.20.81.60.60.91.11.01.2-0.11.31.1-1.10.5-0.60.8
Intermitt. access day 15 inactive lever presses1.12.38.9-1.1-0.5-0.0-0.41.0-2.60.50.1-0.13.0-3.0-0.9
Intermitt. access escalation Index0.30.41.1-0.5-0.9-0.6-1.0-0.8-0.5-0.7-0.40.4-0.50.5-0.6
Intermittent access day 1 total infusions0.00.10.2-0.10.1-0.1-0.1-0.2-0.30.1-0.20.20.5-0.40.4
Intermittent access day 15 total infusions1.01.64.2-1.3-0.8-0.8-0.8-0.8-1.6-0.5-1.31.32.1-2.0-0.3
Intermittent access terminal intake (last 3 days)1.51.94.2-1.6-1.0-1.1-1.0-1.0-1.7-0.9-1.51.52.0-2.0-0.5
Intermittent access total infusions0.81.02.3-1.1-0.8-0.8-1.0-0.5-1.5-0.5-1.01.01.4-1.3-0.4
Intermittent access day 1 locomotion0.30.41.00.90.70.50.5-0.11.00.40.1-0.1-0.90.90.7
Intermittent access day 15 total locomotion0.40.71.3-0.6-0.8-0.8-0.9-0.5-1.1-0.5-1.21.20.6-0.5-0.9
Intermittent access total locomotion0.00.10.20.30.20.0-0.0-0.10.10.1-0.40.4-0.20.20.2
Intermittent access standard deviation0.10.31.1-0.10.00.20.00.5-0.60.2-0.30.31.0-1.0-0.2
Left kidney weight1.15.18.7-2.9-2.6-2.5-2.6-2.4-2.6-2.2-2.12.11.6-1.5-1.4
Right kidney weight0.31.53.1-1.8-1.5-1.2-1.4-1.2-1.6-1.1-0.80.81.0-0.9-0.6
Cocaine induced anxiety0.30.40.80.60.50.80.30.6-0.20.80.8-0.80.2-0.20.9
Post-drug Anxiety0.40.50.7-0.8-0.7-0.6-0.7-0.6-0.8-0.6-0.70.70.7-0.7-0.4
Baseline Anxiety2.93.35.8-1.9-1.9-2.1-1.7-1.9-1.0-2.1-2.42.40.4-0.3-2.1
Tail length0.31.42.2-1.5-1.5-1.5-1.3-1.4-1.3-1.2-0.80.80.8-0.8-0.7
Length with tail1.77.212.7-3.6-3.2-3.1-2.8-2.7-3.2-2.5-2.12.12.3-2.2-2.1
Length without tail1.65.39.2-3.0-2.6-2.4-2.4-2.1-2.6-2.0-2.22.21.5-1.4-2.4
Times rat made contact with spout3.03.44.5-2.1-2.1-2.0-2.1-1.9-1.9-1.8-1.81.81.6-1.5-1.6
Lifetime Intake0.60.71.8-0.9-0.8-0.7-0.9-0.3-1.3-0.4-0.80.81.1-1.1-0.2
Liver weight, left1.52.54.2-2.1-1.8-1.7-1.6-1.5-2.1-1.3-1.01.01.7-1.7-0.7
Liver weight, right1.72.94.5-2.1-1.9-1.8-1.7-1.7-2.0-1.5-1.31.31.9-1.9-1.0
Locomotor activity0.20.30.9-0.4-0.4-0.4-0.5-0.4-0.6-0.3-0.30.30.9-0.9-0.3
Locomotor testing distance0.00.10.10.30.30.20.10.20.20.30.1-0.1-0.30.30.1
Locomotor testing rearing0.20.31.0-0.2-0.5-0.5-0.7-0.3-0.5-0.2-0.40.4-1.01.0-0.4
Locomotion in novel chamber1.31.73.51.51.11.50.91.90.11.71.6-1.6-0.70.61.1
Locomotion in novel chamber post-restriction1.83.04.21.71.71.71.41.91.11.92.0-2.0-1.81.71.5
Fecal boli incidents, locomotor time 11.42.04.51.01.31.31.41.20.11.62.0-2.00.4-0.52.1
Change in fecal boli incidents, locomotor task0.00.00.30.2-0.00.1-0.10.5-0.10.1-0.20.20.1-0.1-0.2
Time >=10cm from walls, locomotor time 10.30.30.50.70.50.70.60.60.40.70.5-0.5-0.40.40.0
Bouts of movement, locomotor time 11.92.14.91.21.71.51.91.21.11.41.7-1.7-0.20.12.2
Total resting periods, locomotor time 12.62.95.71.41.91.82.21.61.21.72.0-2.00.1-0.22.4
Rest time, locomotor task time 10.70.91.60.40.90.81.21.10.11.01.2-1.20.8-0.91.3
Distance moved, locomotor task time 10.60.93.71.10.90.60.7-0.21.90.20.2-0.2-1.51.5-0.2
Vertical activity count, locomotor time 10.30.61.6-0.5-0.7-0.8-0.7-1.20.3-0.9-0.60.6-0.91.0-0.7
Time >=10cm from walls, locomotor time 20.91.31.8-1.2-1.2-1.2-1.3-1.1-1.3-1.0-1.31.30.8-0.8-0.8
Bouts of movement, locomotor time 20.10.10.4-0.2-0.2-0.2-0.4-0.7-0.1-0.3-0.40.4-0.10.10.0
Total resting periods, locomotor time 20.10.10.4-0.3-0.3-0.3-0.5-0.7-0.3-0.3-0.40.40.1-0.1-0.1
Rest time, locomotor task time 20.30.31.10.00.30.40.50.3-0.10.40.3-0.31.1-1.10.7
Distance moved, locomotor task time 20.60.72.01.00.90.60.80.41.40.50.4-0.4-1.31.3-0.1
Vertical activity count, locomotor time 20.40.52.60.2-0.1-0.2-0.2-0.40.6-0.3-0.20.2-1.61.6-0.4
Light reinforcement 10.10.31.1-0.10.20.30.30.4-0.50.60.7-0.70.7-0.71.0
Light reinforcement 20.60.92.00.10.10.6-0.00.9-1.41.01.3-1.31.0-1.01.2
Bone: marrow area2.04.39.9-2.6-2.0-1.9-1.8-1.5-2.6-1.3-1.31.33.1-3.1-0.2
Bone: maximum diameter0.51.02.5-1.6-1.2-1.1-0.9-1.0-1.3-0.8-0.60.60.9-0.8-0.4
Bone: maximum force0.20.31.0-0.9-0.6-0.7-0.5-1.0-0.2-0.6-0.60.6-0.10.1-0.3
Bone: maximum moment0.20.30.9-0.8-0.5-0.7-0.4-1.0-0.0-0.6-0.50.5-0.20.2-0.3
Mean time between licks in bursts0.30.83.30.70.50.60.40.60.50.60.7-0.7-1.81.80.8
Mean num. licks in bursts0.91.44.9-1.1-0.9-0.8-0.9-0.6-1.5-0.7-0.60.62.2-2.2-0.2
Cd content in liver0.10.10.5-0.1-0.1-0.20.3-0.20.7-0.2-0.20.2-0.20.1-0.1
Co content in liver0.60.71.40.70.80.80.80.80.30.90.6-0.61.1-1.21.0
Cu content in liver0.50.61.20.61.00.81.10.60.60.70.5-0.50.8-0.91.0
Fe content in liver1.21.42.4-1.3-1.2-1.3-1.2-1.4-0.8-1.3-1.51.50.3-0.3-1.2
K content in liver1.61.53.51.91.41.01.10.51.90.60.4-0.4-1.61.61.0
Mg content in liver0.10.10.30.2-0.0-0.0-0.2-0.0-0.0-0.2-0.10.1-0.50.50.0
Mn content in liver1.41.62.91.20.91.30.61.5-0.51.51.6-1.60.8-0.91.7
Na content in liver0.50.51.20.1-0.4-0.4-0.7-0.70.1-0.7-1.11.1-0.80.8-1.0
Rb content in liver0.20.20.5-0.6-0.3-0.5-0.0-0.60.2-0.5-0.70.7-0.10.1-0.2
Se content in liver0.40.41.0-0.3-0.3-0.6-0.2-0.90.3-0.9-0.70.71.0-1.00.3
Sr content in liver0.70.61.10.70.80.90.80.90.31.01.0-1.00.2-0.21.0
Zn content in liver0.30.31.00.70.70.40.70.11.00.20.4-0.4-0.30.21.0
Bone: minimum diameter0.40.81.3-1.1-1.0-1.0-1.0-1.0-0.9-0.8-0.80.80.8-0.8-0.5
Time in familiar zone, hab. session 10.50.50.8-0.4-0.3-0.6-0.2-0.60.9-0.9-0.90.9-0.60.7-0.8
Time in novel zone, hab. session 10.30.32.2-0.2-0.4-0.1-0.5-0.0-1.50.30.2-0.20.5-0.60.2
Total zone transitions, hab. session 10.91.21.91.31.31.21.41.21.21.11.1-1.10.1-0.11.0
Total locomotion distance, hab. session 11.52.13.31.61.81.71.81.61.41.61.6-1.6-0.10.11.4
Locomotion velocity, hab. session 12.02.84.01.92.01.92.01.81.81.71.8-1.8-0.40.41.6
Time in familiar zone, hab. session 20.10.10.40.30.30.40.10.6-0.40.50.5-0.50.0-0.10.2
Time in novel zone, hab. session 20.60.60.8-0.9-0.9-0.9-0.7-0.9-0.7-0.8-0.80.80.7-0.7-0.4
Total zone transitions, hab. session 20.30.40.70.20.20.30.20.4-0.50.50.8-0.80.8-0.90.9
Total locomotion distance, hab. session 21.01.32.70.80.81.10.71.4-0.71.51.6-1.60.5-0.61.5
Locomotion velocity, hab. session 21.52.03.71.31.31.51.11.7-0.11.81.9-1.90.2-0.31.8
Novel to familiar place preference ratio0.10.10.3-0.4-0.4-0.4-0.2-0.1-0.2-0.3-0.30.3-0.40.4-0.6
Novelty place preference0.20.20.6-0.4-0.4-0.5-0.3-0.2-0.1-0.4-0.40.4-0.80.8-0.7
Time in novel zone, NPP test0.40.50.8-0.8-0.8-0.8-0.7-0.5-0.5-0.7-0.70.7-0.50.6-0.9
Total zone transitions, NPP test0.60.91.31.11.11.11.11.00.81.01.0-1.00.2-0.31.1
Total locomotion distance, NPP test1.62.23.71.41.51.61.51.70.41.81.9-1.90.3-0.31.7
Locomotion velocity, NPP test2.02.94.61.81.81.91.81.90.82.02.2-2.20.0-0.11.9
Intraocular pressure1.62.34.91.01.41.31.61.60.41.42.1-2.10.8-0.92.2
Delta distance traveled before/after self-admin1.21.25.01.30.60.70.10.80.60.70.6-0.6-2.22.20.0
Delta ambulatory time before/after self-admin0.81.04.11.20.50.60.10.70.30.70.6-0.6-2.02.0-0.0
Parametrial fat weight16.639.159.0-7.7-7.4-7.2-7.3-6.8-6.2-6.7-6.26.23.4-3.2-4.6
Pavlov. Cond. lever latency2.02.59.4-1.7-1.4-0.9-1.4-0.4-3.1-0.4-0.50.52.4-2.4-0.5
Pavlov. Cond. magazine entry latency0.40.61.3-0.0-0.4-0.5-0.5-0.70.8-0.8-0.80.8-1.01.0-1.2
Pavlov. Cond. change in total contacts2.42.68.91.61.30.81.30.33.00.20.3-0.3-2.82.7-0.0
Pavlov. Cond. index score1.31.66.11.10.70.30.6-0.22.5-0.3-0.20.2-2.32.3-0.6
Pavlov. Cond. latency score1.82.27.91.61.10.71.00.22.80.20.2-0.2-2.62.6-0.2
Pavlov. Cond. lever contacts1.01.26.01.10.90.40.9-0.12.4-0.1-0.10.1-1.61.60.1
Pavlov. Cond. magazine entry number0.60.71.7-0.10.20.40.20.7-1.20.80.7-0.71.3-1.31.1
Pavlov. Cond. intertrial magazine entries1.51.73.00.40.71.10.61.7-1.41.61.5-1.51.5-1.61.2
Pavlov. Cond. lever-magazine prob. diff.1.41.86.41.00.50.10.5-0.42.5-0.5-0.40.4-2.42.4-0.9
Pavlov. Cond. response bias0.70.93.00.20.0-0.40.1-0.81.7-0.8-0.80.8-1.41.5-0.9
Pavlov. Cond. lever latency3.95.37.32.72.62.72.52.62.02.52.1-2.1-1.61.52.2
Pavlov. Cond. magazine entry latency2.22.76.7-2.1-1.9-1.6-1.7-1.1-2.6-1.1-1.01.01.9-1.9-0.8
Pavlov. Cond. change in total contacts4.36.89.2-3.0-3.0-2.9-2.9-2.8-2.4-2.8-2.62.61.8-1.7-2.4
Pavlov. Cond. index score4.56.19.2-3.0-2.9-2.8-2.8-2.5-2.7-2.4-2.22.21.7-1.7-2.2
Pavlov. Cond. latency score3.64.87.0-2.7-2.6-2.5-2.5-2.3-2.3-2.2-2.02.01.4-1.4-2.1
Pavlov. Cond. lever contacts4.25.78.1-2.8-2.8-2.8-2.7-2.6-2.3-2.5-2.22.21.4-1.4-2.4
Pavlov. Cond. magazine entry number3.44.16.52.52.32.12.11.72.61.71.5-1.5-2.22.21.6
Pavlov. Cond. intertrial magazine entries1.31.94.51.71.41.21.20.91.80.90.8-0.8-2.12.10.6
Pavlov. Cond. lever-magazine prob. diff.4.96.59.6-3.1-3.0-2.9-2.9-2.7-2.6-2.6-2.42.41.6-1.5-2.4
Pavlov. Cond. response bias4.76.49.5-3.1-2.9-2.8-2.7-2.4-3.0-2.3-2.02.02.3-2.3-2.1
Time in closed arm before self-admin0.20.31.2-0.30.20.20.4-0.1-0.20.10.4-0.41.1-1.1-0.1
Time in closed arm after self-admin0.70.71.10.50.81.01.00.90.11.00.9-0.91.0-1.0-0.1
Time in open arm before self-admin0.20.31.10.3-0.1-0.2-0.4-0.10.1-0.1-0.30.3-1.01.10.7
Time in open arm after self-admin1.41.63.0-1.0-1.4-1.5-1.7-1.3-0.6-1.5-1.51.5-0.50.6-1.1
Bone: periosteal estimation1.02.13.8-1.9-1.6-1.5-1.4-1.5-1.7-1.1-1.11.11.7-1.7-0.3
Bone: periosteal perimeter0.20.31.1-0.9-0.8-0.6-0.7-0.5-1.1-0.2-0.00.00.2-0.10.0
Bone: post-yield work0.10.10.2-0.3-0.10.10.10.3-0.30.30.2-0.20.4-0.5-0.0
Progressive ratio test 1 active lever presses0.40.51.0-0.8-0.6-0.7-0.6-0.5-0.9-0.5-0.70.71.0-1.00.1
Progressive ratio test 1 breakpoint0.50.61.0-0.9-0.6-0.7-0.7-0.6-0.9-0.6-0.80.81.0-1.00.0
Progressive ratio test 1 inactive lever presses0.60.83.2-0.5-0.10.0-0.10.7-1.50.50.1-0.11.7-1.80.5
Progressive ratio test 2 active lever presses0.40.51.4-0.7-0.5-0.5-0.5-0.2-0.9-0.3-0.70.71.2-1.20.1
Progressive ratio test 2 breakpoint0.50.61.6-0.8-0.6-0.5-0.6-0.2-1.1-0.3-0.70.71.3-1.30.1
Progressive ratio test 2 inactive lever presses1.22.07.3-1.3-1.2-0.8-1.3-0.0-2.7-0.2-0.70.72.2-2.2-0.0
Incentive Sensitization - Responses0.20.21.2-0.3-0.4-0.1-0.50.4-1.10.2-0.10.10.6-0.60.3
Incentive Sensitization - Breakpoint0.30.31.7-0.5-0.6-0.3-0.70.3-1.30.1-0.20.20.8-0.80.1
Sum of active levers in priming session hrs 5-60.60.51.20.40.80.80.70.90.10.70.7-0.70.6-0.61.1
Progressive ratio1.32.14.71.01.31.31.32.2-0.11.62.0-2.00.1-0.21.8
Food seeking constrained by brief footshock1.41.72.81.51.51.31.11.21.71.01.0-1.0-1.31.31.3
Seeking ratio, punishment vs. effort1.01.53.1-0.7-1.0-1.1-1.1-1.70.4-1.5-1.81.8-0.40.5-1.5
Retroperitoneal fat weight18.076.9112.2-10.6-10.1-10.1-9.6-10.0-7.7-9.5-9.09.05.2-4.9-7.2
Reaction time number correct1.12.03.91.41.31.61.21.60.21.92.0-2.0-0.50.41.4
Reaction time mean minus median1.02.44.3-2.1-1.9-1.9-1.8-1.4-1.7-1.7-1.31.30.9-0.8-0.9
Reaction time mean minus median AUC0.82.03.5-1.9-1.9-1.8-1.8-1.3-1.7-1.5-1.11.10.3-0.2-0.7
Reaction time num false alarms2.12.94.42.02.12.12.01.61.42.11.7-1.70.3-0.31.9
Reaction time num false alarms AUC1.52.43.71.91.91.91.91.41.31.91.6-1.60.1-0.11.5
Reaction time trials correct on left1.12.03.91.41.31.61.21.60.21.92.0-2.0-0.50.41.4
Reaction time trials on left1.01.93.91.41.21.61.11.60.11.92.0-2.0-0.60.41.3
Reaction time mean2.74.37.6-2.8-2.5-2.5-2.3-2.2-2.1-2.3-1.71.71.6-1.5-1.1
Reaction time mean AUC2.13.35.8-2.4-2.2-2.2-2.1-2.0-1.8-2.1-1.51.51.3-1.3-0.8
Median of all reaction times2.63.66.2-2.5-2.2-2.3-2.0-2.1-1.8-2.1-1.61.61.6-1.5-1.0
Reaction time omissions0.50.72.0-1.3-1.2-1.1-1.2-0.6-1.4-0.8-0.10.1-0.10.1-0.1
Reaction time false alarm rate0.50.71.21.01.10.91.10.61.00.90.6-0.60.4-0.40.9
Reaction time premature initiation rate0.30.41.60.10.30.30.40.2-0.10.40.2-0.21.2-1.30.6
Reaction time premature initiations0.71.32.10.91.11.21.11.10.01.41.2-1.21.1-1.21.4
Std. dev. reaction times1.63.05.6-2.4-2.1-2.2-2.0-1.8-1.7-2.0-1.51.50.9-0.8-1.0
Reaction time trials completed1.01.93.91.41.21.61.11.60.11.92.0-2.0-0.60.41.3
Reaction time trials AUC1.12.04.11.31.21.61.21.7-0.12.02.0-2.0-0.30.21.4
Run reversals in cocaine runway, females2.42.34.4-1.3-1.9-1.8-2.1-1.8-1.3-1.8-1.71.7-0.00.1-1.2
Run reversals in cocaine runway, males1.81.94.0-1.4-1.3-1.6-1.3-2.0-0.1-1.8-1.71.7-0.10.2-1.1
Latency to leave start box in cocaine runway0.50.61.30.80.50.90.31.1-0.61.10.9-0.90.5-0.50.6
Latency to leave start box in cocaine runway, F0.30.31.3-0.2-0.10.0-0.10.3-1.10.40.2-0.21.1-1.10.3
Latency to leave start box in cocaine runway, M1.31.22.61.40.91.50.61.6-0.01.41.4-1.4-0.20.20.5
Std. dev. time between licks in bursts0.91.22.71.11.00.90.90.81.10.80.9-0.9-1.61.61.3
Total sessions with >9 infusions0.60.71.5-0.9-0.9-0.9-1.0-0.4-1.2-0.6-0.80.81.0-1.00.1
Short access day 1 total inactive lever presses0.81.12.20.20.60.80.51.2-1.31.30.9-0.91.4-1.50.9
Short access day 10 total inactive lever presses0.40.93.5-0.3-0.10.4-0.01.0-1.91.00.7-0.71.4-1.5-0.3
Short access day 1 total infusions0.50.71.80.70.70.70.61.1-0.11.00.9-0.90.4-0.41.4
Short access day 10 total infusions0.20.31.0-0.6-0.5-0.3-0.5-0.1-1.0-0.1-0.50.50.6-0.6-0.2
Short access total infusions0.40.51.3-0.8-0.7-0.7-0.8-0.2-1.1-0.4-0.70.70.7-0.70.0
Short access day 1 locomotion0.20.20.7-0.2-0.5-0.3-0.7-0.2-0.9-0.2-0.50.50.5-0.5-0.0
Short access day 10 total locomotion0.20.40.70.70.70.70.80.60.60.80.6-0.6-0.40.40.3
Short access total locomotion0.20.20.70.60.30.20.1-0.00.50.30.0-0.0-0.90.80.7
One hour access (0.3 mA shock)0.20.31.1-0.10.00.2-0.11.1-0.80.3-0.10.10.8-0.8-0.1
Compulsive drug intake1.61.94.31.41.51.41.72.11.71.11.4-1.4-1.01.00.3
One hour access (shock baseline)0.81.22.0-1.0-1.0-0.9-1.1-0.8-1.4-0.7-1.41.41.1-1.0-1.0
Social response proportion3.94.47.2-2.1-2.5-2.3-2.7-2.2-2.1-2.3-2.02.01.4-1.4-1.7
Social responses0.20.31.1-0.5-0.5-0.6-0.4-1.1-0.4-0.5-0.30.30.6-0.60.0
Social time0.81.22.9-0.9-1.3-1.3-1.4-1.7-0.8-1.1-0.90.9-0.20.3-0.9
Soleus weight0.00.00.1-0.3-0.2-0.1-0.0-0.1-0.10.20.1-0.10.1-0.1-0.0
Bone: stiffness0.00.10.2-0.5-0.2-0.2-0.1-0.5-0.30.00.0-0.0-0.40.40.2
Tibialis anterior weight0.51.73.5-1.9-1.7-1.7-1.5-1.4-1.0-1.4-1.11.1-0.10.2-1.3
Time to tail flick, vehicle, before self-admin2.52.68.6-1.5-1.2-1.0-1.2-0.5-2.3-0.7-0.60.62.9-2.9-0.7
Time to tail flick, vehicle, after self-admin0.40.51.9-0.10.60.41.1-0.10.70.30.3-0.31.4-1.40.3
Time to tail flick, test, before self-admin0.20.20.6-0.00.50.30.60.40.40.20.3-0.30.7-0.70.4
Time to tail flick, test, after self-admin1.41.55.10.00.50.71.01.0-1.01.21.2-1.22.2-2.3-0.4
Delta time to tail flick, vehicle, before/after SA1.11.02.70.91.21.01.60.61.50.90.9-0.9-0.40.40.9
Delta time to tail flick, test, before/after SA0.30.30.60.10.10.30.30.4-0.80.60.7-0.70.7-0.8-0.2
Tibia length1.84.98.0-2.8-2.4-2.6-2.3-2.7-1.7-2.5-2.12.11.9-1.8-1.0
Ambulatory time before self-admin0.40.61.4-0.8-0.7-0.9-0.5-1.20.3-1.0-1.11.10.1-0.1-0.7
Ambulatory time after self-admin0.80.94.40.90.20.30.1-0.11.10.10.0-0.0-2.12.1-0.5
Bone: tissue strength0.70.71.1-0.9-1.0-1.1-1.0-1.0-0.3-1.0-0.90.9-0.10.2-0.8
Total heroin consumption0.50.61.9-0.2-0.20.2-0.30.7-1.30.50.3-0.31.3-1.40.8
Bone: trabecular number0.30.62.10.70.40.40.40.20.90.20.4-0.4-1.41.5-0.3
Bone: trabecular spacing1.82.43.3-1.8-1.4-1.6-1.3-1.5-1.3-1.5-1.71.71.8-1.7-1.0
Bone: trabecular thickness0.30.41.10.60.50.40.50.11.00.20.3-0.3-1.01.00.3
Bone: trabecular tissue density0.60.91.9-0.5-0.6-1.0-0.7-1.10.2-1.1-1.41.4-1.01.0-0.8
Water consumed over 24 hours0.40.52.2-0.4-0.2-0.0-0.00.1-0.90.20.3-0.31.5-1.50.3
Number of responses in last shaping day0.91.02.00.50.80.81.01.4-0.21.11.0-1.01.3-1.40.7