Hub : Genes

Ndufa12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ndufa12 0.06 0.03 8.4e-10 0.06 0.08 0.08 0.08 2.1e-07 5.0e-09 3.1e-09 4.3e-09
2 Brain gene expression Ndufa12 0.44 0.1 0.0e+00 0.29 0.33 0.31 0.32 4.1e-27 6.6e-32 1.5e-29 2.7e-30
3 pVTA gene expression Ndufa12 0.03 0.02 5.5e-03 0.05 0.03 0.04 0.05 9.7e-05 4.0e-03 3.8e-04 1.1e-04
4 IC gene expression Ndufa12 0.29 0.12 9.8e-08 0.15 0.17 0.18 0.18 1.0e-06 1.2e-07 3.9e-08 7.2e-08
5 BLA gene expression Ndufa12 0.12 0.07 2.4e-03 0.01 0.01 0 0 5.5e-02 1.1e-01 2.0e-01 3.2e-01
6 Adipose gene expression Ndufa12 0.4 0.13 0.0e+00 0.22 0.2 0.23 0.22 1.5e-23 3.8e-22 4.9e-25 2.0e-24
7 Liver gene expression Ndufa12 0.4 0.09 0.0e+00 0.43 0.46 0.46 0.44 2.0e-52 2.3e-56 2.5e-56 2.2e-54
8 OFC gene expression Ndufa12 0.23 0.11 5.5e-04 0.15 0.12 0.12 0.12 2.4e-04 8.5e-04 7.0e-04 9.1e-04
9 Brain mRNA stability Ndufa12 0.04 0.02 1.4e-03 0.03 0.03 0.04 0.04 1.8e-03 4.9e-04 5.4e-05 2.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.20.6-0.3-0.5-0.1-0.5-0.4-0.6-0.10.8-0.5
Area under the delay curve0.30.41.6-0.3-1.0-0.4-0.2-0.0-0.50.00.3-1.3
BMI with tail2.79.417.5-3.5-2.7-3.1-3.8-4.2-2.8-2.4-3.01.2
BMI without tail4.814.624.9-4.4-3.7-3.9-4.0-5.0-3.8-3.3-3.22.5
Body weight14.061.284.3-9.0-8.0-8.3-8.1-9.2-7.6-7.3-7.44.8
Weight adjusted by age0.10.20.8-0.4-0.1-0.2-0.3-0.90.10.1-0.80.3
Bone surface0.40.71.0-0.9-1.0-0.9-1.0-1.0-0.9-0.80.0-0.3
Bone volume0.51.01.7-1.1-1.1-1.0-1.2-1.3-1.1-0.80.0-0.3
Breakpoint value in progressive ratio session1.11.43.61.11.31.10.60.61.51.90.6-1.0
Number of licking bursts0.10.20.6-0.2-0.2-0.3-0.80.2-0.5-0.40.8-0.3
Context. condit. distance diff. score0.70.92.4-0.9-0.9-1.1-0.6-0.8-0.9-0.8-1.60.6
Locomotion velocity, session 10.50.61.40.80.80.70.80.51.20.90.0-0.4
Locomotion distance, session 10.10.10.6-0.1-0.5-0.2-0.5-0.2-0.0-0.1-0.8-0.1
Locomotion velocity, session 20.20.20.60.10.80.00.4-0.50.60.60.10.1
Locomotion distance, session 20.50.71.4-0.8-1.0-0.8-1.2-0.7-0.8-0.8-1.00.3
Locomotion velocity, session 30.30.31.7-0.20.40.1-0.2-0.90.60.1-1.3-0.1
Locomotion distance, session 30.70.82.3-0.9-0.7-0.8-1.1-0.9-0.6-0.7-1.50.4
Stereotopy head waving bouts, day 31.51.83.01.41.11.71.21.51.31.11.3-1.2
Stereotopy head waving duration, day 30.50.61.00.80.70.90.60.91.00.70.6-0.8
Locomotion velocity, session 70.60.61.5-0.9-0.3-0.9-0.0-1.2-0.2-0.3-1.10.9
Locomotion distance, session 70.30.31.0-0.5-0.5-1.0-0.3-0.4-0.3-0.4-0.90.5
Stereotopy head waving bouts, day 70.10.10.30.10.60.3-0.1-0.10.40.40.50.2
Stereotopy head waving duration, day 70.10.20.30.20.60.4-0.1-0.00.50.50.6-0.3
Locomotion velocity, session 80.60.72.4-0.9-0.5-0.9-0.6-1.1-0.4-0.2-1.60.7
Locomotion distance, session 83.45.010.2-2.3-2.3-2.5-2.2-2.1-2.0-1.8-3.21.4
Degree of sensitization distance0.20.20.40.50.5-0.10.40.50.50.50.6-0.2
Degree of sensitization stereotypy0.20.20.80.20.90.3-0.2-0.10.50.60.7-0.1
Conditioned locomotion0.10.10.4-0.0-0.6-0.00.7-0.2-0.3-0.4-0.0-0.4
Cocaine response after cond. corrected0.40.51.2-0.7-1.1-0.7-0.5-0.3-0.9-0.70.2-0.5
Cocaine response after cond. not corrected0.30.41.2-0.7-1.1-0.5-0.5-0.3-0.9-0.7-0.1-0.2
Cocaine response before conditioning0.10.10.30.30.40.50.10.20.30.4-0.50.5
Saline control response0.40.51.3-0.7-0.1-0.6-0.8-0.9-0.4-1.0-0.21.1
Bone: connectivity density0.20.41.50.60.40.70.30.40.30.41.2-0.4
Bone: cortical apparent density0.30.41.2-0.5-0.2-0.70.2-0.8-0.2-0.2-1.11.0
Bone: cortical area1.92.95.9-1.8-2.4-1.6-1.8-1.7-1.8-1.7-1.20.3
Bone: cortical porosity0.10.10.3-0.4-0.4-0.1-0.2-0.5-0.2-0.3-0.2-0.5
Bone: cortical porosity0.20.20.4-0.4-0.7-0.2-0.2-0.4-0.3-0.3-0.3-0.6
Bone: cortical thickness1.01.63.7-1.4-1.9-1.1-1.1-1.4-1.2-1.3-1.20.3
Bone: cortical thickness0.60.71.90.60.50.91.00.11.00.80.6-1.4
Bone: cortical tissue density0.30.51.4-0.5-0.2-0.70.2-0.8-0.2-0.3-1.21.1
Condit. Reinf. active minus inactive responses1.92.23.41.61.81.81.41.31.61.70.8-0.8
Condit. Reinf. active-inactive response ratio1.41.52.01.31.31.40.91.21.21.41.0-1.0
Condit. Reinf. active responses3.74.56.52.42.52.62.11.92.32.11.7-1.2
Condit. Reinf. inactive responses2.43.04.21.92.11.91.81.51.91.61.6-1.0
Incentive salience index mean0.40.50.90.90.90.90.60.70.80.90.3-0.1
Condit. Reinf. lever presses0.10.10.2-0.2-0.4-0.4-0.4-0.3-0.3-0.0-0.40.4
Condit. Reinf. active minus inactive responses0.30.41.50.41.2-0.0-0.2-0.10.81.1-0.20.2
Condit. Reinf. active-inactive response ratio0.10.10.7-0.10.5-0.2-0.9-0.20.00.3-0.30.4
Condit. Reinf. active responses0.30.41.30.31.2-0.00.1-0.20.91.1-0.20.2
Condit. Reinf. inactive responses0.91.22.51.01.20.71.60.21.51.50.2-0.8
Condit. Reinf. lever presses0.30.41.4-0.30.8-0.4-0.2-1.20.60.8-0.00.5
Condit. Reinf. lever reinforcers received0.20.31.10.21.0-0.1-0.0-0.30.81.0-0.40.2
Conditioned reinforcement - actives0.30.61.2-0.4-0.7-1.1-1.10.5-0.8-0.60.60.8
Conditioned reinforcement - inactives0.20.31.20.40.10.4-0.21.10.00.30.9-0.1
Conditioned locomotion0.40.51.6-0.5-0.5-1.0-1.3-0.0-0.7-0.5-0.10.9
Patch foraging indifference point 0 sec0.10.21.20.30.00.10.40.30.1-0.01.10.3
Patch foraging indifference point AUC0.20.30.7-0.3-0.4-0.4-0.7-0.3-0.6-0.80.50.6
Delay disc. indifference point, 0s delay0.20.21.10.20.30.40.0-0.00.41.10.3-0.7
Delay disc. indifference point, 16s delay0.60.72.1-0.7-1.4-0.9-0.7-0.3-0.8-0.40.0-1.2
Delay disc. indifference point, 2s delay0.70.81.7-0.9-1.3-0.9-0.9-0.4-0.9-0.7-1.00.6
Delay disc. indifference point, 24s delay1.01.13.2-1.1-1.8-1.0-0.9-1.1-1.1-0.7-0.9-0.3
Delay disc. indifference point, 4s delay0.20.20.5-0.0-0.6-0.20.40.2-0.2-0.10.7-0.7
Delay disc. indifference point, 8s delay0.50.63.90.0-0.4-0.10.20.2-0.10.50.9-2.0
Indifference point function ln k0.10.10.2-0.2-0.10.20.3-0.40.20.4-0.5-0.4
Indifference point function log k0.10.10.2-0.2-0.10.20.3-0.40.20.4-0.5-0.4
Patch foraging total patch changes 0 sec0.10.21.20.30.10.20.50.20.20.01.10.2
Patch foraging total patch changes 12 sec0.70.92.0-0.9-1.0-0.9-0.8-0.8-1.0-1.30.41.4
Patch foraging total patch changes 18 sec0.40.63.0-0.1-0.2-0.4-0.50.3-0.6-0.71.21.7
Patch foraging total patch changes 24 sec0.71.22.5-1.0-0.9-1.1-1.0-1.0-1.0-1.40.11.6
Patch foraging total patch changes 6 sec0.20.42.20.50.40.50.30.30.3-0.11.50.2
Patch foraging time to switch 0 sec0.00.10.6-0.2-0.1-0.70.20.2-0.1-0.1-0.10.1
Patch foraging water rate 0 sec0.91.93.5-1.4-1.9-0.8-1.4-1.3-1.7-1.6-1.20.8
Patch foraging water rate 12 sec1.94.06.2-2.2-2.0-1.6-2.5-1.9-2.4-2.3-1.11.6
Patch foraging water rate 18 sec0.10.21.1-0.0-0.10.2-1.10.1-0.5-0.60.40.0
Patch foraging water rate 24 sec5.17.111.7-2.8-3.4-2.7-2.8-1.9-3.2-2.4-2.81.6
Patch foraging water rate 6 sec5.98.611.1-3.3-3.3-3.0-3.2-3.0-3.2-2.8-2.51.9
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.1-0.20.30.10.20.30.30.2-0.2
Distance traveled before self-admin0.70.92.3-0.6-1.1-0.9-1.1-0.5-0.8-0.7-1.50.5
Distance traveled after self-admin0.10.21.0-0.1-0.4-0.4-0.30.00.10.3-1.0-0.1
Extensor digitorum longus weight0.10.61.4-0.9-0.8-0.4-1.2-0.8-0.8-0.7-0.1-0.3
Bone: elastic displacement3.23.75.12.11.72.32.01.72.01.91.4-2.2
Bone: elastic work1.72.23.71.61.21.61.51.31.61.31.1-1.9
Bone: endosteal estimation0.10.31.3-0.1-0.3-0.3-0.40.1-0.5-0.10.9-1.2
Bone: endosteal perimeter1.42.96.7-1.9-2.6-1.6-1.6-1.3-2.3-1.8-1.00.2
Epididymis fat weight2.58.712.0-3.1-2.9-3.1-3.2-3.1-2.9-2.5-3.51.9
Delta time in closed arm before/after self-admin0.40.41.1-0.6-0.5-0.3-1.0-0.0-0.5-0.7-0.60.5
Delta time in open arm before/after self-admin2.22.25.01.21.71.41.40.61.72.21.1-1.5
Diff in mean of infusions in LGA sessions0.20.20.70.40.30.30.40.80.60.40.1-0.4
Delay discount exponential model param0.40.41.30.51.10.60.30.20.60.2-0.21.1
Extinction: sum of active levers before priming0.10.10.3-0.10.1-0.1-0.60.20.10.20.2-0.5
Active lever presses in extinction session 60.20.20.9-0.5-0.3-0.2-0.5-0.9-0.10.2-0.6-0.3
Bone: final force0.40.71.4-0.8-1.2-0.7-1.0-0.7-1.0-0.80.2-0.9
Bone: final moment0.50.81.9-0.8-1.4-0.7-1.1-0.7-1.1-0.90.1-0.8
Food consumed during 24 hour testing period0.30.41.1-0.5-0.3-0.7-0.6-0.6-0.4-0.7-0.41.0
Glucose0.10.10.90.20.00.90.1-0.20.1-0.00.4-0.0
Heart weight1.11.63.6-1.4-1.0-1.5-1.8-1.9-0.9-0.7-1.2-0.1
Delay discount hyperbolic model param0.40.41.60.61.30.70.40.30.70.30.00.8
Intermittent access intake day 1-15 change0.50.92.4-0.7-1.0-0.8-0.90.1-0.9-1.2-0.91.5
Intermittent access intake escalation0.40.82.0-0.7-1.0-0.6-0.80.1-0.8-1.1-1.01.4
Intermittent access intake escalation 20.40.41.5-0.4-0.6-0.3-0.2-0.0-0.4-0.8-0.91.2
Intermitt. access day 1 inactive lever presses1.14.39.42.12.11.71.43.11.81.82.6-1.5
Intermitt. access day 15 inactive lever presses0.20.40.70.50.70.80.00.80.70.9-0.8-0.3
Intermitt. access escalation Index0.00.00.10.20.2-0.10.3-0.30.20.3-0.2-0.1
Intermittent access day 1 total infusions1.52.44.1-1.7-1.5-1.9-2.0-0.8-1.9-1.4-0.91.1
Intermittent access day 15 total infusions1.92.93.7-1.8-1.9-1.5-1.9-0.9-1.9-1.9-1.51.7
Intermittent access terminal intake (last 3 days)2.02.63.4-1.7-1.8-1.5-1.8-1.0-1.8-1.7-1.61.5
Intermittent access total infusions1.92.23.7-1.6-1.6-1.6-1.9-0.7-1.8-1.4-1.31.2
Intermittent access day 1 locomotion0.70.91.5-1.2-1.2-1.1-0.9-0.6-1.2-1.1-0.10.2
Intermittent access day 15 total locomotion0.20.41.3-0.5-0.5-0.7-0.80.2-0.6-0.6-0.31.1
Intermittent access total locomotion0.81.01.6-1.1-1.0-1.1-1.3-0.5-1.1-1.1-0.50.9
Intermittent access standard deviation0.61.33.3-0.5-0.9-0.9-1.21.0-1.2-1.6-0.11.8
Left kidney weight4.520.926.5-5.0-4.6-4.6-4.8-5.1-4.2-4.3-4.93.5
Right kidney weight3.817.321.1-4.6-4.3-4.6-4.5-4.6-4.0-3.9-3.92.6
Cocaine induced anxiety1.72.44.11.31.81.81.80.21.82.00.5-1.6
Post-drug Anxiety0.80.81.50.71.11.11.0-0.31.11.20.0-0.8
Baseline Anxiety2.12.43.5-1.5-1.6-1.7-1.8-0.8-1.6-1.9-1.21.6
Tail length9.938.850.3-7.1-6.6-6.4-5.3-6.9-6.2-6.2-5.65.5
Length with tail14.261.979.7-8.9-8.2-8.3-7.4-8.4-7.7-7.9-7.46.3
Length without tail7.825.132.4-5.7-5.1-5.4-5.1-5.4-4.7-4.9-5.03.3
Times rat made contact with spout2.42.85.6-1.4-1.5-1.2-2.4-0.5-2.1-2.2-0.32.0
Lifetime Intake2.02.43.5-1.7-1.7-1.6-1.8-1.1-1.9-1.5-1.21.1
Liver weight, left6.811.217.6-3.5-4.0-3.8-3.1-2.6-3.6-4.2-1.72.9
Liver weight, right4.27.49.3-3.0-3.0-2.7-2.5-3.1-2.6-2.7-2.42.4
Locomotor activity4.97.79.1-3.0-3.0-2.9-2.9-2.9-2.6-2.6-2.91.9
Locomotor testing distance2.44.36.6-2.1-2.4-2.6-2.3-1.6-2.0-1.9-2.21.1
Locomotor testing rearing0.40.81.9-0.7-1.4-1.3-0.6-0.2-0.9-1.0-1.00.6
Locomotion in novel chamber0.30.31.4-0.4-0.4-0.6-0.1-0.8-0.2-0.2-1.20.4
Locomotion in novel chamber post-restriction0.10.20.4-0.4-0.5-0.6-0.60.2-0.5-0.50.00.3
Fecal boli incidents, locomotor time 10.30.40.9-0.9-0.9-0.8-0.2-1.0-0.7-0.2-0.3-0.1
Change in fecal boli incidents, locomotor task1.71.72.91.51.71.51.21.61.31.10.6-0.8
Time >=10cm from walls, locomotor time 11.01.13.20.91.30.80.90.31.11.10.5-1.8
Bouts of movement, locomotor time 10.50.61.90.40.70.70.3-0.20.81.00.7-1.4
Total resting periods, locomotor time 10.91.02.00.71.11.10.70.01.11.30.6-1.4
Rest time, locomotor task time 11.82.23.31.31.61.81.50.71.71.81.1-1.6
Distance moved, locomotor task time 10.91.33.5-0.8-1.0-1.4-1.0-0.4-1.0-1.2-1.11.9
Vertical activity count, locomotor time 11.94.65.7-2.0-2.3-2.4-2.1-1.6-2.1-2.2-2.32.2
Time >=10cm from walls, locomotor time 20.30.51.10.80.80.40.50.50.41.00.8-0.8
Bouts of movement, locomotor time 20.20.30.9-0.3-0.4-0.10.2-0.80.10.3-0.8-0.9
Total resting periods, locomotor time 20.20.41.8-0.10.00.30.4-0.60.40.8-0.5-1.3
Rest time, locomotor task time 21.72.23.21.41.71.71.10.81.61.81.0-1.7
Distance moved, locomotor task time 20.91.12.6-0.9-1.0-1.3-0.9-0.7-1.0-1.1-0.71.6
Vertical activity count, locomotor time 25.27.29.4-2.9-3.1-3.0-2.9-2.4-2.9-2.7-1.92.3
Light reinforcement 10.20.51.4-0.5-0.2-0.2-1.2-0.9-0.4-0.6-0.40.9
Light reinforcement 20.60.92.91.01.01.00.30.90.50.41.7-0.8
Bone: marrow area0.10.31.3-0.1-0.2-0.3-0.40.1-0.5-0.00.9-1.2
Bone: maximum diameter1.93.67.2-2.1-2.7-1.6-2.0-1.8-2.3-1.9-1.40.5
Bone: maximum force0.20.41.0-0.5-0.7-0.5-0.9-0.6-0.5-0.20.1-1.0
Bone: maximum moment0.20.41.0-0.5-0.8-0.5-1.0-0.6-0.5-0.30.0-1.0
Mean time between licks in bursts0.10.20.7-0.3-0.2-0.4-0.4-0.40.00.7-0.9-0.6
Mean num. licks in bursts0.10.21.2-0.0-0.10.1-0.20.1-0.3-0.5-0.41.1
Cd content in liver0.20.20.7-0.10.4-0.2-0.4-0.40.30.80.2-0.6
Co content in liver0.30.31.7-0.2-0.6-0.60.30.0-0.2-0.1-1.30.5
Cu content in liver0.40.41.0-0.8-0.8-0.7-0.1-0.8-0.5-1.00.30.2
Fe content in liver0.50.71.0-0.9-1.0-1.0-0.8-0.9-0.8-0.4-0.7-0.7
K content in liver0.50.51.40.0-0.1-0.11.20.1-0.0-0.91.01.2
Mg content in liver0.80.92.50.81.00.81.60.31.10.41.20.0
Mn content in liver0.10.10.70.20.30.20.8-0.10.3-0.30.20.3
Na content in liver0.10.20.3-0.5-0.6-0.10.3-0.6-0.5-0.3-0.00.4
Rb content in liver0.70.82.50.70.40.61.60.70.70.61.2-1.1
Se content in liver0.10.10.3-0.10.5-0.40.3-0.20.50.3-0.20.2
Sr content in liver0.20.20.5-0.1-0.5-0.2-0.7-0.0-0.2-0.1-0.70.5
Zn content in liver2.83.17.3-1.8-1.0-1.8-1.5-1.9-1.1-1.5-2.02.7
Bone: minimum diameter4.17.411.2-3.0-3.4-2.6-3.1-2.7-3.1-2.6-2.21.0
Time in familiar zone, hab. session 10.10.10.4-0.00.6-0.1-0.1-0.40.50.6-0.1-0.1
Time in novel zone, hab. session 10.90.91.40.91.11.10.81.20.80.51.0-1.1
Total zone transitions, hab. session 12.73.85.8-2.1-2.0-2.0-2.4-2.0-1.6-1.1-2.31.6
Total locomotion distance, hab. session 12.94.18.1-2.0-1.6-2.3-2.8-1.8-1.5-1.1-2.52.0
Locomotion velocity, hab. session 13.85.49.9-2.2-2.0-2.6-3.1-2.0-1.8-1.4-2.92.5
Time in familiar zone, hab. session 20.00.00.10.00.40.1-0.1-0.10.30.2-0.3-0.0
Time in novel zone, hab. session 20.40.41.00.60.70.50.40.40.60.80.6-1.0
Total zone transitions, hab. session 20.60.82.6-0.5-0.7-1.3-1.3-0.4-0.4-0.1-1.60.1
Total locomotion distance, hab. session 20.50.72.1-0.4-0.6-1.1-1.4-0.0-0.5-0.1-1.30.4
Locomotion velocity, hab. session 20.60.82.4-0.4-0.8-1.3-1.4-0.1-0.6-0.2-1.50.5
Novel to familiar place preference ratio0.40.41.4-0.30.4-0.8-0.1-0.80.30.5-0.61.2
Novelty place preference0.40.41.0-0.00.8-0.60.1-0.60.70.8-0.41.0
Time in novel zone, NPP test0.30.40.8-0.20.7-0.7-0.0-0.80.50.7-0.50.9
Total zone transitions, NPP test1.11.64.0-1.2-1.4-1.6-1.3-1.2-0.8-0.6-2.00.2
Total locomotion distance, NPP test0.91.22.8-0.9-1.0-1.2-1.4-0.9-0.8-0.7-1.71.0
Locomotion velocity, NPP test0.50.82.1-0.6-0.8-0.9-1.0-0.5-0.5-0.6-1.41.0
Intraocular pressure1.31.95.01.71.41.60.82.21.01.01.2-0.7
Delta distance traveled before/after self-admin0.20.20.50.40.30.30.70.60.50.40.6-0.3
Delta ambulatory time before/after self-admin1.01.22.31.00.91.01.50.71.21.11.1-1.2
Parametrial fat weight0.30.72.2-0.8-0.6-0.40.4-1.50.20.3-1.0-1.3
Pavlov. Cond. lever latency0.30.41.0-0.9-0.4-1.0-0.6-0.9-0.4-0.2-0.7-0.2
Pavlov. Cond. magazine entry latency0.30.41.10.60.80.80.30.50.61.0-0.30.2
Pavlov. Cond. change in total contacts0.40.41.40.70.50.90.21.20.10.10.80.5
Pavlov. Cond. index score0.30.41.00.80.71.00.40.60.60.80.3-0.1
Pavlov. Cond. latency score0.40.51.20.90.71.10.40.80.60.70.40.0
Pavlov. Cond. lever contacts0.10.10.30.50.20.60.20.40.20.00.40.5
Pavlov. Cond. magazine entry number0.10.20.5-0.5-0.5-0.6-0.3-0.5-0.3-0.70.20.2
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.1-0.10.30.40.1-0.1-0.30.0-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.70.60.80.30.50.50.80.2-0.2
Pavlov. Cond. response bias0.30.40.90.80.70.90.60.70.40.60.40.1
Pavlov. Cond. lever latency0.20.31.10.4-0.50.30.51.0-0.2-0.60.4-0.2
Pavlov. Cond. magazine entry latency0.20.31.2-0.4-0.20.2-0.4-0.3-0.6-0.6-0.61.1
Pavlov. Cond. change in total contacts1.62.54.1-1.8-1.2-1.9-1.5-2.0-1.3-0.8-2.01.3
Pavlov. Cond. index score0.70.91.6-1.1-0.6-0.7-0.8-1.3-0.8-0.5-1.11.2
Pavlov. Cond. latency score0.40.51.2-0.8-0.3-0.4-0.4-1.0-0.6-0.3-0.91.1
Pavlov. Cond. lever contacts0.30.41.5-0.70.1-0.5-0.9-1.2-0.20.4-0.50.2
Pavlov. Cond. magazine entry number0.70.81.61.00.70.60.90.81.00.91.0-1.3
Pavlov. Cond. intertrial magazine entries0.10.20.40.10.40.10.2-0.50.60.6-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.81.12.1-1.1-0.7-0.8-0.9-1.2-1.0-0.8-1.21.4
Pavlov. Cond. response bias0.50.71.8-1.0-0.3-0.9-1.2-1.3-0.6-0.1-0.90.6
Time in closed arm before self-admin0.30.40.9-0.50.2-0.7-0.8-1.0-0.3-0.3-0.90.7
Time in closed arm after self-admin0.80.91.8-1.0-0.6-1.2-1.3-1.1-0.9-0.8-0.50.4
Time in open arm before self-admin0.20.20.60.4-0.20.60.60.50.20.00.3-0.8
Time in open arm after self-admin2.42.65.31.31.61.71.60.91.92.30.9-1.7
Bone: periosteal estimation0.71.42.8-1.3-1.7-1.2-1.3-1.2-1.4-1.0-0.5-0.6
Bone: periosteal perimeter1.22.14.5-1.6-2.1-1.5-1.4-1.5-1.6-1.3-1.1-0.2
Bone: post-yield work0.10.21.2-0.3-0.1-0.0-1.1-0.1-0.6-0.30.10.0
Progressive ratio test 1 active lever presses7.08.612.2-3.1-3.3-3.3-3.2-1.9-3.5-3.4-1.82.4
Progressive ratio test 1 breakpoint7.28.812.5-3.1-3.3-3.3-3.3-1.8-3.5-3.4-1.82.5
Progressive ratio test 1 inactive lever presses0.10.10.3-0.2-0.4-0.3-0.30.5-0.4-0.40.40.1
Progressive ratio test 2 active lever presses1.41.72.6-1.3-1.1-1.2-1.6-1.0-1.4-1.4-0.91.5
Progressive ratio test 2 breakpoint1.51.72.6-1.2-1.1-1.1-1.6-0.9-1.4-1.4-1.01.6
Progressive ratio test 2 inactive lever presses0.20.30.8-0.6-0.4-0.2-0.9-0.2-0.6-0.6-0.50.6
Incentive Sensitization - Responses0.40.61.4-0.7-0.5-0.4-0.8-0.6-0.6-0.7-1.01.2
Incentive Sensitization - Breakpoint0.30.41.0-0.5-0.3-0.2-0.5-0.5-0.4-0.5-0.91.0
Sum of active levers in priming session hrs 5-60.40.41.0-0.7-0.3-0.4-1.0-0.8-0.6-0.3-0.00.9
Progressive ratio1.01.63.11.51.11.31.41.81.31.30.3-0.9
Food seeking constrained by brief footshock1.51.94.1-1.2-1.2-1.5-1.1-0.5-1.5-2.0-0.71.8
Seeking ratio, punishment vs. effort1.62.33.3-1.6-1.4-1.6-1.5-1.7-1.5-1.8-0.71.4
Retroperitoneal fat weight2.39.913.5-3.5-3.4-3.4-2.5-3.7-2.9-2.8-3.52.2
Reaction time number correct0.00.10.30.10.00.3-0.40.2-0.2-0.10.2-0.6
Reaction time mean minus median0.61.43.01.31.71.00.90.71.71.60.4-0.6
Reaction time mean minus median AUC0.71.84.11.42.01.31.00.91.91.60.5-0.4
Reaction time num false alarms1.01.42.81.21.11.11.31.11.20.71.7-1.0
Reaction time num false alarms AUC1.32.03.41.51.31.21.31.41.41.11.9-1.5
Reaction time trials correct on left0.00.10.30.10.00.3-0.40.2-0.2-0.10.2-0.6
Reaction time trials on left0.10.10.50.20.10.3-0.30.3-0.1-0.10.3-0.7
Reaction time mean0.00.10.10.30.20.2-0.10.30.20.2-0.3-0.2
Reaction time mean AUC0.00.00.20.10.10.1-0.30.20.10.0-0.4-0.0
Median of all reaction times0.10.10.3-0.2-0.4-0.2-0.50.1-0.4-0.4-0.50.1
Reaction time omissions2.33.34.22.02.01.31.81.52.02.11.3-2.0
Reaction time false alarm rate1.11.52.71.31.11.01.41.21.31.01.6-1.0
Reaction time premature initiation rate0.10.20.8-0.1-0.2-0.4-0.90.2-0.00.5-0.5-0.2
Reaction time premature initiations0.10.21.5-0.2-0.2-0.4-1.20.1-0.30.1-0.4-0.1
Std. dev. reaction times0.81.52.81.41.61.01.00.91.71.50.6-0.9
Reaction time trials completed0.10.10.50.20.10.3-0.30.3-0.1-0.10.3-0.7
Reaction time trials AUC0.00.10.40.10.00.3-0.40.2-0.2-0.20.3-0.6
Run reversals in cocaine runway, females1.31.32.7-1.1-1.7-1.2-0.9-0.7-1.1-1.1-1.50.3
Run reversals in cocaine runway, males0.10.10.40.20.70.4-0.00.10.4-0.1-0.10.1
Latency to leave start box in cocaine runway0.20.20.8-0.30.10.0-0.3-0.90.0-0.2-0.70.2
Latency to leave start box in cocaine runway, F0.81.02.01.01.41.31.00.41.30.80.3-0.7
Latency to leave start box in cocaine runway, M2.52.44.6-1.6-1.5-1.5-1.6-2.2-1.4-1.2-1.51.1
Std. dev. time between licks in bursts0.50.72.70.30.6-0.50.2-0.11.11.6-0.7-1.1
Total sessions with >9 infusions2.42.94.7-1.9-2.1-1.8-1.7-1.3-2.2-2.0-0.81.0
Short access day 1 total inactive lever presses0.20.31.10.2-0.10.2-0.11.1-0.2-0.20.8-0.5
Short access day 10 total inactive lever presses1.74.16.32.22.22.42.11.92.52.20.7-1.4
Short access day 1 total infusions0.30.41.0-0.7-1.0-0.5-0.5-0.6-0.9-0.6-0.6-0.1
Short access day 10 total infusions2.43.14.4-2.1-1.9-2.0-2.0-1.7-2.0-1.7-1.31.0
Short access total infusions1.72.12.9-1.7-1.7-1.5-1.4-1.6-1.7-1.2-1.30.6
Short access day 1 locomotion1.01.21.7-1.3-1.3-1.0-1.3-0.9-1.3-1.2-0.60.7
Short access day 10 total locomotion0.81.55.81.10.60.40.62.40.50.62.1-1.0
Short access total locomotion0.70.81.4-0.9-1.1-1.1-1.00.0-1.2-1.10.40.8
One hour access (0.3 mA shock)5.36.18.0-2.4-2.6-2.3-2.8-1.1-2.8-2.7-2.42.8
Compulsive drug intake0.10.10.70.3-0.20.50.9-0.00.0-0.10.10.2
One hour access (shock baseline)2.84.38.0-2.1-1.9-2.2-2.8-0.9-2.2-2.0-1.82.3
Social response proportion2.63.05.0-2.1-1.9-1.5-1.9-2.2-1.5-1.5-1.90.1
Social responses1.92.55.2-1.7-1.7-1.5-1.6-2.0-1.1-1.1-2.30.3
Social time0.81.13.6-0.7-1.0-0.7-1.90.0-1.1-1.7-0.20.4
Soleus weight0.20.61.4-0.6-1.1-0.4-0.8-0.7-0.7-0.6-0.2-1.2
Bone: stiffness1.72.74.0-2.0-1.9-2.0-1.9-2.0-1.7-1.4-0.8-0.2
Tibialis anterior weight0.20.74.50.50.40.50.20.40.50.50.8-2.1
Time to tail flick, vehicle, before self-admin2.62.75.5-1.6-1.7-1.7-1.9-0.6-1.9-1.4-0.52.3
Time to tail flick, vehicle, after self-admin0.81.02.00.81.00.50.61.30.91.21.4-0.9
Time to tail flick, test, before self-admin0.10.10.5-0.4-0.3-0.30.4-0.7-0.2-0.60.10.1
Time to tail flick, test, after self-admin0.20.20.3-0.5-0.50.1-0.4-0.5-0.6-0.50.1-0.0
Delta time to tail flick, vehicle, before/after SA3.23.04.51.61.91.71.91.11.91.81.5-2.1
Delta time to tail flick, test, before/after SA0.10.10.50.20.40.7-0.20.10.30.5-0.0-0.5
Tibia length10.829.934.6-5.9-5.7-5.7-5.6-5.1-5.5-5.3-5.74.6
Ambulatory time before self-admin1.01.52.3-1.0-1.5-1.5-1.5-0.7-1.2-1.2-1.40.8
Ambulatory time after self-admin0.40.52.3-0.5-0.9-0.7-0.3-0.5-0.10.0-1.5-0.2
Bone: tissue strength0.50.50.8-0.7-0.7-0.9-0.9-0.6-0.7-0.90.2-0.2
Total heroin consumption0.40.51.30.60.30.60.60.00.81.20.2-1.1
Bone: trabecular number0.20.41.40.60.20.70.30.60.10.31.2-0.7
Bone: trabecular spacing0.20.30.60.40.40.60.50.20.80.7-0.60.2
Bone: trabecular thickness0.50.71.2-0.9-0.7-1.1-1.1-1.1-0.8-0.8-0.10.4
Bone: trabecular tissue density0.10.10.6-0.0-0.2-0.10.8-0.00.0-0.1-0.10.4
Water consumed over 24 hours1.72.24.0-1.5-1.2-2.0-2.0-0.9-1.6-1.8-0.41.4
Number of responses in last shaping day0.10.10.2-0.00.3-0.3-0.40.3-0.1-0.4-0.30.4