Nbeal2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Nbeal2 0.64 0.19 0.0e+00 0.34 0.34 0.34 0.34 5.7e-32 2.2e-32 1.3e-32 1.6e-32
2 OFC gene expression Nbeal2 0.19 0.16 3.1e-03 0.04 0.06 0.07 0.05 3.9e-02 1.7e-02 1.0e-02 2.7e-02
3 Adipose mRNA stability Nbeal2 0.13 0.09 1.0e-09 0.07 0.08 0.07 0.07 3.4e-08 5.9e-09 1.9e-08 2.5e-08
4 Adipose gene expression Nbeal2 0.33 0.15 0.0e+00 0.25 0.26 0.25 0.25 4.2e-27 1.4e-28 5.0e-28 4.7e-28
5 Adipose isoform ratio XM_039082643.1 0.09 0.07 1.0e-08 0.07 0.07 0.07 0.07 2.3e-08 1.9e-08 5.8e-08 4.7e-08
6 NAcc mRNA stability Nbeal2 0.08 0.07 4.8e-08 0.06 0.07 0.05 0.06 1.0e-07 3.8e-08 1.4e-06 7.6e-08
7 NAcc gene expression Nbeal2 0.19 0.11 0.0e+00 0.2 0.21 0.21 0.21 2.4e-22 4.4e-24 2.1e-23 1.8e-23
8 Brain mRNA stability Nbeal2 0.17 0.13 4.7e-12 0.12 0.13 0.12 0.12 2.7e-11 2.3e-12 1.1e-11 2.8e-11
9 Liver gene expression Nbeal2 0.27 0.13 0.0e+00 0.26 0.29 0.29 0.29 3.4e-29 6.7e-33 1.2e-32 4.2e-32
10 NAcc intron excision ratio chr8_110607420_110607507 0.06 0.25 3.1e-03 0.02 0.01 0.02 0.02 3.3e-03 6.2e-03 3.8e-03 1.4e-03
11 PL mRNA stability Nbeal2 0.09 0.09 4.9e-07 0.05 0.06 0.05 0.05 2.7e-06 6.0e-07 3.2e-06 2.2e-06
12 BLA mRNA stability Nbeal2 0.12 0.12 3.8e-05 0.04 0.07 0.06 0.05 2.6e-03 1.4e-04 6.7e-04 7.7e-04
13 Adipose alternative TSS XM_006244008.4 0.08 0.05 2.1e-09 0.06 0.07 0.07 0.06 8.5e-07 1.4e-08 7.0e-08 1.1e-07
14 Adipose alternative TSS XM_006244008.4 0.07 0.05 3.3e-09 0.05 0.07 0.06 0.06 1.2e-06 2.0e-08 9.3e-08 1.9e-07
15 Adipose alternative TSS XM_039082645.1 0.07 0.05 4.1e-09 0.05 0.07 0.06 0.06 1.3e-06 2.4e-08 1.1e-07 2.0e-07
16 PL gene expression Nbeal2 0.18 0.12 0.0e+00 0.16 0.16 0.16 0.16 7.9e-17 4.5e-17 1.2e-17 2.7e-17
17 BLA gene expression Nbeal2 0.4 0.23 0.0e+00 0.28 0.29 0.29 0.28 3.4e-15 5.3e-16 7.9e-16 1.4e-15
18 Liver mRNA stability Nbeal2 0.03 0.03 2.7e-04 0.01 0.01 0 0.01 2.9e-02 1.8e-02 1.2e-01 3.9e-02
19 pVTA gene expression Nbeal2 0.19 0.2 1.4e-04 0.07 0.06 0.04 0.06 5.4e-04 1.3e-03 5.3e-03 9.7e-04
20 Adipose isoform ratio XM_006244008.4 0.03 0.02 1.5e-03 0.01 0.01 0.01 0.01 6.8e-03 9.0e-03 1.3e-02 2.9e-02
21 IL gene expression Nbeal2 0.88 0.09 3.9e-06 0.15 0.16 0.2 0.2 1.7e-04 1.4e-04 1.3e-05 1.4e-05
22 Brain isoform ratio XM_039082644.1 0.41 0.19 5.6e-05 0.04 0.04 0.02 0.03 2.9e-04 5.4e-05 5.9e-03 1.1e-03
23 Brain alternative TSS XM_039082644.1 0.32 0.18 1.5e-03 0.02 0.03 0.02 0.01 6.3e-03 2.1e-03 9.7e-03 1.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.00.00.1-0.20.00.20.2-0.20.20.20.20.20.30.20.2-0.2-0.20.2-0.20.20.2-0.20.1-0.10.10.1
Area under the delay curve2.12.32.91.61.7-1.6-1.61.6-1.5-1.6-1.5-1.6-1.2-1.5-1.51.61.6-1.61.6-1.5-1.61.5-1.51.5-1.1-1.0
BMI with tail0.41.44.2-1.4-1.41.31.2-1.21.21.21.11.21.41.01.1-1.1-1.11.1-1.11.11.1-1.70.7-2.0-0.2-0.1
BMI without tail1.83.85.5-2.2-2.02.02.0-2.02.02.02.02.02.01.92.0-2.0-1.91.9-2.01.91.9-2.21.5-2.31.21.2
Body weight6.728.232.4-5.6-5.75.55.5-5.55.55.45.45.45.45.35.4-5.4-5.45.4-5.45.45.4-5.75.1-5.53.73.7
Weight adjusted by age0.20.20.4-0.5-0.30.50.5-0.50.50.50.50.50.30.50.5-0.5-0.50.5-0.50.50.5-0.60.4-0.40.30.3
Bone surface0.00.10.20.10.4-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.3-0.30.30.3-0.30.3-0.3-0.30.1-0.30.0-0.4-0.4
Bone volume0.00.00.1-0.00.2-0.0-0.10.1-0.1-0.1-0.1-0.10.0-0.1-0.10.10.1-0.10.1-0.1-0.1-0.0-0.2-0.1-0.3-0.2
Breakpoint value in progressive ratio session0.10.10.2-0.3-0.40.30.3-0.30.30.30.30.30.40.30.3-0.3-0.30.3-0.30.30.3-0.30.20.20.30.3
Number of licking bursts0.20.20.40.50.2-0.5-0.40.4-0.4-0.4-0.5-0.4-0.6-0.4-0.40.40.4-0.40.4-0.4-0.40.4-0.30.5-0.4-0.5
Context. condit. distance diff. score0.00.00.0-0.0-0.00.00.0-0.00.00.00.00.0-0.10.00.0-0.0-0.00.0-0.00.00.0-0.1-0.0-0.00.00.0
Locomotion velocity, session 10.10.10.30.20.3-0.2-0.20.2-0.3-0.2-0.3-0.2-0.3-0.3-0.30.30.3-0.30.3-0.3-0.20.1-0.20.2-0.6-0.6
Locomotion distance, session 10.81.12.0-1.2-1.01.11.1-1.11.11.11.01.11.30.91.0-1.0-1.01.0-1.01.01.0-1.30.9-1.40.10.2
Locomotion velocity, session 20.30.30.70.40.5-0.5-0.50.5-0.5-0.5-0.6-0.5-0.3-0.6-0.50.60.6-0.60.6-0.6-0.60.4-0.50.1-0.8-0.8
Locomotion distance, session 20.10.10.9-0.00.3-0.0-0.00.0-0.1-0.1-0.1-0.10.0-0.2-0.10.10.1-0.10.1-0.1-0.1-0.2-0.1-0.3-0.9-0.9
Locomotion velocity, session 30.10.10.4-0.50.00.40.4-0.30.30.30.30.30.40.20.3-0.3-0.30.3-0.30.30.3-0.50.1-0.7-0.10.0
Locomotion distance, session 31.01.11.80.81.3-1.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.1-1.01.01.0-1.01.1-1.1-1.00.8-1.20.6-1.3-1.2
Stereotopy head waving bouts, day 30.00.00.2-0.1-0.50.20.2-0.20.20.20.20.20.20.20.2-0.2-0.20.2-0.20.20.2-0.20.2-0.20.10.1
Stereotopy head waving duration, day 30.20.30.5-0.4-0.70.50.5-0.50.50.60.50.60.30.60.6-0.6-0.60.6-0.60.60.6-0.50.7-0.10.60.5
Locomotion velocity, session 70.20.30.4-0.6-0.20.50.5-0.60.50.60.50.60.10.50.5-0.6-0.60.6-0.60.60.6-0.60.6-0.00.40.3
Locomotion distance, session 70.60.81.60.81.2-0.8-0.90.8-0.8-0.8-0.9-0.8-1.3-0.9-0.90.80.8-0.80.8-0.8-0.80.7-0.81.1-0.9-0.9
Stereotopy head waving bouts, day 70.10.10.20.20.3-0.3-0.30.3-0.2-0.3-0.2-0.3-0.1-0.2-0.30.30.3-0.30.3-0.3-0.30.4-0.40.10.20.3
Stereotopy head waving duration, day 70.20.30.5-0.5-0.50.50.5-0.50.50.50.60.50.60.50.5-0.5-0.50.5-0.50.50.5-0.40.4-0.60.60.7
Locomotion velocity, session 80.30.30.8-0.7-0.40.60.6-0.60.50.50.50.50.80.40.5-0.5-0.50.5-0.50.50.5-0.80.4-0.9-0.3-0.2
Locomotion distance, session 80.20.30.9-0.8-0.20.60.6-0.60.60.60.50.60.60.40.5-0.5-0.50.5-0.50.50.5-0.90.4-1.0-0.3-0.2
Degree of sensitization distance1.21.31.7-1.0-1.21.11.1-1.11.11.11.11.10.91.21.2-1.2-1.21.2-1.21.21.2-1.01.3-0.51.21.1
Degree of sensitization stereotypy0.00.10.6-0.10.00.10.0-0.00.10.00.20.00.20.10.1-0.1-0.10.1-0.10.10.00.2-0.1-0.20.70.8
Conditioned locomotion3.03.54.32.02.1-2.0-2.01.9-1.9-1.9-1.9-1.9-1.9-1.9-1.91.91.9-1.91.9-1.9-1.92.0-1.91.9-1.2-1.1
Cocaine response after cond. corrected0.20.30.7-0.5-0.80.50.5-0.50.50.50.50.50.40.50.5-0.5-0.50.5-0.50.50.5-0.40.4-0.50.50.5
Cocaine response after cond. not corrected1.82.02.8-1.4-1.71.41.4-1.41.41.41.41.41.31.41.4-1.4-1.41.4-1.41.41.4-1.41.3-1.41.11.1
Cocaine response before conditioning1.11.41.9-1.3-1.01.31.2-1.21.21.21.21.21.21.21.2-1.2-1.21.2-1.21.21.2-1.41.1-1.40.60.6
Saline control response1.31.71.9-1.3-1.21.31.4-1.41.41.31.31.41.31.41.4-1.4-1.41.4-1.41.41.4-1.31.4-0.91.31.2
Bone: connectivity density0.20.30.70.60.9-0.6-0.60.6-0.6-0.6-0.5-0.6-0.5-0.5-0.50.50.5-0.50.5-0.5-0.60.6-0.60.7-0.2-0.1
Bone: cortical apparent density0.30.30.50.60.7-0.6-0.60.6-0.6-0.6-0.5-0.6-0.7-0.5-0.60.60.6-0.60.6-0.6-0.60.7-0.60.6-0.1-0.1
Bone: cortical area0.10.20.30.40.2-0.4-0.40.4-0.4-0.4-0.4-0.4-0.5-0.4-0.40.40.4-0.40.4-0.4-0.40.4-0.30.3-0.5-0.5
Bone: cortical porosity0.10.10.50.30.4-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.1-0.20.20.2-0.20.1-0.2-0.20.4-0.10.70.20.2
Bone: cortical porosity0.20.20.90.60.7-0.5-0.40.4-0.4-0.4-0.4-0.4-0.5-0.4-0.40.40.4-0.40.4-0.4-0.40.6-0.30.9-0.0-0.1
Bone: cortical thickness0.10.20.5-0.4-0.70.40.4-0.40.40.40.40.40.20.40.4-0.4-0.40.4-0.40.40.4-0.40.4-0.50.30.2
Bone: cortical thickness0.00.00.0-0.1-0.10.10.1-0.10.10.10.10.1-0.10.10.1-0.1-0.10.1-0.10.10.1-0.10.1-0.00.0-0.0
Bone: cortical tissue density0.30.30.50.60.7-0.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.6-0.60.60.6-0.60.6-0.6-0.60.7-0.70.6-0.1-0.1
Condit. Reinf. active minus inactive responses0.10.10.3-0.2-0.30.30.3-0.30.30.30.30.30.10.40.3-0.3-0.30.3-0.40.30.3-0.20.40.10.50.4
Condit. Reinf. active-inactive response ratio0.20.30.5-0.4-0.60.50.5-0.50.50.50.50.50.20.50.5-0.5-0.50.5-0.50.50.5-0.40.6-0.10.70.6
Condit. Reinf. active responses0.00.00.10.20.1-0.2-0.20.2-0.1-0.1-0.1-0.2-0.2-0.1-0.10.10.1-0.10.1-0.1-0.10.2-0.20.20.30.3
Condit. Reinf. inactive responses0.60.71.30.80.9-0.9-0.90.9-0.9-0.9-0.8-0.9-0.7-0.9-0.90.90.9-0.90.8-0.9-0.90.9-1.10.5-0.4-0.3
Incentive salience index mean0.10.10.10.30.2-0.2-0.20.2-0.3-0.2-0.3-0.2-0.3-0.3-0.20.20.2-0.20.2-0.2-0.20.2-0.20.3-0.3-0.3
Condit. Reinf. lever presses1.52.02.61.41.5-1.4-1.41.4-1.4-1.4-1.5-1.4-1.3-1.5-1.41.41.4-1.41.5-1.5-1.41.2-1.41.1-1.6-1.6
Condit. Reinf. active minus inactive responses2.12.63.1-1.7-1.81.71.7-1.71.71.71.61.71.71.61.7-1.7-1.71.7-1.61.61.7-1.81.7-1.60.90.9
Condit. Reinf. active-inactive response ratio1.71.82.4-1.4-1.51.41.4-1.41.41.41.41.41.41.31.4-1.4-1.41.4-1.31.31.3-1.41.3-1.50.90.9
Condit. Reinf. active responses1.82.53.0-1.6-1.71.61.6-1.61.61.61.61.61.71.61.6-1.6-1.61.6-1.61.61.6-1.61.6-1.51.11.0
Condit. Reinf. inactive responses0.00.00.10.20.2-0.1-0.10.1-0.1-0.1-0.2-0.1-0.1-0.1-0.10.10.1-0.10.2-0.1-0.10.1-0.00.2-0.2-0.3
Condit. Reinf. lever presses2.53.44.2-2.0-2.01.91.9-1.91.91.91.91.92.11.81.9-1.9-1.91.9-1.81.81.9-2.01.8-1.91.11.1
Condit. Reinf. lever reinforcers received2.02.83.3-1.7-1.81.71.7-1.71.71.71.71.71.81.71.7-1.7-1.71.7-1.71.71.7-1.81.8-1.61.01.0
Conditioned reinforcement - actives0.40.41.70.60.5-0.5-0.50.5-0.6-0.6-0.7-0.5-0.6-0.7-0.50.50.5-0.50.5-0.6-0.5-0.0-0.70.6-1.2-1.3
Conditioned reinforcement - inactives0.81.01.21.00.8-1.0-1.01.0-1.0-1.0-1.0-1.0-1.1-1.0-1.01.01.0-1.01.0-1.0-1.00.8-1.00.8-0.9-1.0
Conditioned locomotion0.40.51.00.70.7-0.7-0.60.7-0.7-0.7-0.7-0.7-0.5-0.7-0.70.70.7-0.70.7-0.7-0.60.3-0.80.5-1.0-1.0
Patch foraging indifference point 0 sec1.01.52.3-1.2-1.01.31.3-1.31.31.31.31.31.21.31.3-1.3-1.31.3-1.21.31.3-1.11.5-0.91.00.9
Patch foraging indifference point AUC0.10.10.3-0.4-0.30.30.3-0.30.30.30.30.30.50.30.3-0.3-0.30.3-0.30.30.3-0.20.1-0.30.50.5
Delay disc. indifference point, 0s delay0.00.00.10.20.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.0-0.2-0.20.20.2-0.20.2-0.2-0.2-0.0-0.10.2-0.3-0.3
Delay disc. indifference point, 16s delay1.11.11.71.01.3-1.0-1.11.1-1.0-1.1-1.0-1.1-1.0-1.0-1.01.11.1-1.11.1-1.1-1.11.1-1.01.0-0.8-0.8
Delay disc. indifference point, 2s delay0.30.30.60.60.7-0.6-0.60.6-0.6-0.6-0.6-0.6-0.3-0.6-0.60.60.6-0.60.6-0.6-0.60.4-0.60.6-0.4-0.4
Delay disc. indifference point, 24s delay0.90.81.40.91.2-0.9-0.90.9-0.9-0.9-0.9-0.9-0.6-0.9-0.90.90.9-0.90.9-0.9-0.90.9-0.91.0-0.6-0.5
Delay disc. indifference point, 4s delay2.22.32.71.61.6-1.6-1.61.6-1.5-1.6-1.5-1.6-1.3-1.5-1.51.61.6-1.61.6-1.5-1.61.5-1.61.5-1.1-1.0
Delay disc. indifference point, 8s delay2.12.12.71.51.7-1.5-1.51.5-1.5-1.5-1.5-1.5-1.3-1.5-1.51.51.5-1.51.5-1.5-1.51.4-1.51.5-1.0-1.0
Indifference point function ln k0.20.31.60.30.6-0.4-0.40.4-0.5-0.4-0.5-0.4-0.5-0.5-0.50.50.5-0.50.5-0.5-0.40.2-0.4-0.0-1.3-1.2
Indifference point function log k0.20.31.60.30.6-0.4-0.40.4-0.5-0.4-0.5-0.4-0.5-0.5-0.50.50.5-0.50.5-0.5-0.40.2-0.4-0.0-1.3-1.2
Patch foraging total patch changes 0 sec1.11.82.8-1.3-1.21.41.4-1.41.41.41.41.41.41.41.4-1.4-1.41.4-1.31.41.4-1.21.7-1.01.00.9
Patch foraging total patch changes 12 sec0.91.21.7-1.0-1.01.11.1-1.11.11.11.11.11.31.11.1-1.1-1.11.1-1.01.11.1-0.71.2-0.91.31.3
Patch foraging total patch changes 18 sec2.43.13.6-1.6-1.81.81.8-1.81.81.81.81.81.81.81.9-1.9-1.91.9-1.81.91.9-1.91.8-1.11.51.3
Patch foraging total patch changes 24 sec3.03.74.3-1.9-2.12.02.0-2.02.02.02.02.02.02.02.0-2.0-2.02.0-1.92.02.0-1.82.1-1.71.61.5
Patch foraging total patch changes 6 sec0.10.20.4-0.4-0.20.40.4-0.40.40.40.40.40.50.50.4-0.4-0.40.4-0.40.40.4-0.10.6-0.20.60.6
Patch foraging time to switch 0 sec0.10.20.30.50.3-0.5-0.50.5-0.5-0.5-0.4-0.5-0.6-0.4-0.50.50.5-0.50.5-0.5-0.50.6-0.40.4-0.1-0.1
Patch foraging water rate 0 sec0.10.20.4-0.4-0.50.50.5-0.50.50.50.40.50.60.40.5-0.5-0.50.5-0.40.50.5-0.70.5-0.3-0.2-0.2
Patch foraging water rate 12 sec0.30.40.7-0.7-0.80.70.7-0.70.70.70.70.70.50.70.7-0.7-0.70.7-0.70.70.7-0.80.8-0.60.20.1
Patch foraging water rate 18 sec0.00.00.2-0.3-0.30.20.2-0.20.20.20.10.20.10.10.1-0.1-0.10.1-0.10.10.1-0.20.2-0.5-0.4-0.3
Patch foraging water rate 24 sec0.71.01.4-1.0-1.11.01.0-1.01.01.01.01.01.21.01.0-1.0-1.01.0-1.01.01.0-1.00.9-0.91.01.0
Patch foraging water rate 6 sec0.30.50.7-0.8-0.60.70.7-0.70.70.70.70.70.60.60.7-0.7-0.70.7-0.60.70.7-0.90.8-0.80.10.2
Seeking ratio, delayed vs. immediate footshock2.52.93.51.91.5-1.8-1.81.8-1.8-1.8-1.8-1.8-1.6-1.8-1.81.81.8-1.81.5-1.8-1.81.4-1.41.7-1.6-1.6
Distance traveled before self-admin0.00.00.2-0.1-0.00.10.1-0.10.10.10.10.10.00.00.1-0.1-0.10.1-0.20.10.1-0.40.2-0.3-0.0-0.1
Distance traveled after self-admin0.20.20.30.40.5-0.5-0.50.4-0.5-0.4-0.5-0.4-0.6-0.4-0.50.50.5-0.50.4-0.5-0.50.5-0.20.4-0.4-0.4
Extensor digitorum longus weight0.20.60.70.80.7-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.80.8-0.80.8-0.8-0.80.7-0.70.6-0.8-0.8
Bone: elastic displacement0.00.00.2-0.2-0.40.20.2-0.20.20.20.20.20.20.20.2-0.2-0.20.2-0.20.20.2-0.20.3-0.30.10.0
Bone: elastic work0.50.71.1-0.9-1.00.90.8-0.80.80.80.80.80.80.80.8-0.8-0.80.8-0.80.80.8-1.00.8-1.10.20.2
Bone: endosteal estimation0.10.20.3-0.4-0.20.40.4-0.40.40.40.40.40.20.40.4-0.4-0.40.4-0.50.40.4-0.40.60.10.30.2
Bone: endosteal perimeter1.22.42.91.61.7-1.6-1.61.6-1.6-1.6-1.6-1.6-1.5-1.6-1.61.61.6-1.61.6-1.6-1.61.5-1.41.4-1.5-1.5
Epididymis fat weight0.30.71.4-0.8-1.20.80.8-0.80.80.80.80.81.10.80.8-0.8-0.80.8-0.90.80.8-0.90.4-1.00.80.9
Delta time in closed arm before/after self-admin0.10.10.20.40.3-0.4-0.40.4-0.4-0.4-0.4-0.4-0.3-0.4-0.40.40.4-0.40.4-0.4-0.40.4-0.40.4-0.4-0.4
Delta time in open arm before/after self-admin0.30.30.4-0.6-0.10.50.5-0.50.50.50.50.50.30.50.5-0.5-0.50.5-0.50.50.5-0.50.6-0.50.50.5
Diff in mean of infusions in LGA sessions0.00.00.10.1-0.3-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.1-0.10.1-0.2-0.1-0.0-0.0
Delay discount exponential model param2.52.63.3-1.7-1.81.71.7-1.71.71.71.61.71.31.71.7-1.7-1.71.7-1.71.71.7-1.61.7-1.61.11.1
Extinction: sum of active levers before priming0.00.00.2-0.1-0.10.10.1-0.10.10.10.10.1-0.00.10.1-0.1-0.10.1-0.20.10.1-0.40.10.3-0.0-0.1
Active lever presses in extinction session 60.30.30.7-0.6-0.10.50.5-0.50.50.50.50.50.60.50.5-0.5-0.50.5-0.60.60.6-0.80.6-0.30.40.3
Bone: final force0.81.31.9-1.2-1.41.21.2-1.21.21.21.21.21.21.11.2-1.2-1.21.2-1.21.21.2-1.21.2-1.20.90.9
Bone: final moment1.11.82.5-1.4-1.61.41.3-1.31.41.31.31.31.41.31.3-1.3-1.31.3-1.31.31.3-1.41.4-1.40.90.9
Food consumed during 24 hour testing period1.41.71.9-1.3-1.41.41.4-1.41.31.31.31.31.41.31.3-1.3-1.31.3-1.31.31.3-1.41.4-1.40.80.8
Glucose0.30.41.1-0.7-0.60.70.7-0.60.60.60.70.61.00.60.6-0.6-0.60.6-0.60.60.6-0.60.5-0.80.40.5
Heart weight2.63.64.9-1.9-2.21.91.9-1.91.91.91.91.92.01.91.9-1.9-1.91.9-1.91.91.9-1.72.0-2.21.51.5
Delay discount hyperbolic model param2.52.63.3-1.7-1.81.71.7-1.71.71.71.61.71.31.71.7-1.7-1.71.7-1.71.71.7-1.61.7-1.61.11.1
Intermittent access intake day 1-15 change0.50.50.80.80.7-0.7-0.70.7-0.7-0.7-0.8-0.7-0.9-0.8-0.70.70.7-0.70.6-0.7-0.70.5-0.80.5-0.8-0.9
Intermittent access intake escalation0.40.40.80.70.6-0.6-0.60.6-0.6-0.6-0.7-0.6-0.9-0.7-0.60.60.6-0.60.5-0.6-0.60.4-0.70.6-0.8-0.9
Intermittent access intake escalation 20.00.00.1-0.1-0.20.20.2-0.20.20.20.10.2-0.10.10.2-0.2-0.20.2-0.20.20.2-0.40.1-0.2-0.1-0.1
Intermitt. access day 1 inactive lever presses0.00.00.00.00.1-0.0-0.00.0-0.0-0.1-0.1-0.0-0.1-0.1-0.00.10.1-0.10.1-0.1-0.10.0-0.0-0.1-0.2-0.1
Intermitt. access day 15 inactive lever presses0.60.70.80.80.8-0.9-0.90.9-0.9-0.9-0.8-0.9-0.9-0.8-0.90.90.9-0.90.9-0.9-0.90.9-0.80.7-0.5-0.5
Intermitt. access escalation Index0.00.00.1-0.10.30.00.0-0.00.00.00.00.0-0.20.00.0-0.0-0.00.00.00.00.0-0.00.00.2-0.1-0.1
Intermittent access day 1 total infusions0.00.00.20.10.2-0.1-0.10.1-0.1-0.1-0.2-0.1-0.1-0.2-0.10.10.1-0.10.2-0.1-0.1-0.0-0.20.2-0.4-0.4
Intermittent access day 15 total infusions0.30.41.00.60.7-0.6-0.50.5-0.6-0.6-0.6-0.5-0.8-0.6-0.60.50.5-0.50.5-0.6-0.50.2-0.70.6-0.9-1.0
Intermittent access terminal intake (last 3 days)0.20.20.80.40.5-0.4-0.30.3-0.4-0.3-0.4-0.3-0.6-0.4-0.40.30.3-0.30.3-0.3-0.3-0.0-0.50.4-0.8-0.9
Intermittent access total infusions0.50.61.50.70.8-0.7-0.70.7-0.7-0.7-0.8-0.7-0.8-0.8-0.70.70.7-0.70.7-0.7-0.70.3-0.80.7-1.1-1.2
Intermittent access day 1 locomotion0.10.10.20.30.4-0.3-0.30.3-0.3-0.3-0.4-0.3-0.4-0.3-0.30.30.3-0.30.4-0.3-0.30.3-0.30.4-0.4-0.5
Intermittent access day 15 total locomotion0.60.61.10.71.0-0.8-0.80.7-0.8-0.7-0.8-0.7-0.9-0.8-0.80.80.8-0.80.7-0.8-0.70.6-0.80.9-0.8-0.9
Intermittent access total locomotion1.21.41.81.21.3-1.1-1.11.1-1.2-1.2-1.2-1.1-1.1-1.2-1.11.11.2-1.11.2-1.2-1.10.9-1.21.0-1.3-1.2
Intermittent access standard deviation0.20.20.4-0.5-0.60.50.5-0.50.50.50.40.50.20.40.5-0.5-0.50.5-0.50.50.5-0.60.4-0.50.10.1
Left kidney weight0.82.15.2-1.7-1.41.51.5-1.41.41.41.51.42.01.41.4-1.4-1.41.4-1.31.31.3-1.31.1-2.30.91.2
Right kidney weight0.20.51.6-0.9-0.40.70.7-0.70.70.70.70.71.10.60.7-0.6-0.60.6-0.70.60.6-0.70.4-1.30.50.6
Cocaine induced anxiety0.50.60.70.80.7-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.80.8-0.80.8-0.8-0.80.7-0.80.6-0.6-0.5
Post-drug Anxiety0.20.20.40.50.4-0.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.50.50.5-0.50.5-0.5-0.50.7-0.40.3-0.00.0
Baseline Anxiety0.10.20.30.30.5-0.4-0.40.4-0.4-0.4-0.4-0.4-0.6-0.3-0.40.40.4-0.40.4-0.4-0.40.5-0.30.6-0.1-0.2
Tail length7.021.122.5-4.7-4.64.74.7-4.74.74.74.74.74.64.74.7-4.7-4.74.7-4.74.74.7-4.54.5-4.04.34.1
Length with tail9.635.337.2-6.1-6.06.16.1-6.16.16.16.16.15.96.16.1-6.1-6.16.1-6.16.16.1-5.96.0-5.45.25.0
Length without tail6.414.015.8-3.8-4.03.83.8-3.83.83.83.83.83.83.83.8-3.8-3.83.8-3.83.83.8-3.93.8-3.52.92.8
Times rat made contact with spout0.40.50.7-0.6-0.80.70.7-0.70.70.70.70.70.80.70.7-0.7-0.70.7-0.70.70.7-0.60.7-0.90.70.7
Lifetime Intake0.40.41.10.60.7-0.6-0.60.6-0.6-0.6-0.7-0.6-0.6-0.7-0.60.60.6-0.60.6-0.6-0.60.3-0.70.7-1.0-1.0
Liver weight, left0.10.10.7-0.2-0.00.20.2-0.20.20.20.30.20.20.30.2-0.2-0.20.2-0.30.30.2-0.10.20.20.80.8
Liver weight, right1.32.12.6-1.6-1.41.51.5-1.51.51.41.51.41.61.51.5-1.4-1.41.4-1.51.51.4-1.51.2-1.51.51.6
Locomotor activity5.69.010.1-3.2-3.13.13.1-3.13.13.13.03.12.63.13.1-3.1-3.13.1-3.13.13.1-3.23.0-2.62.11.9
Locomotor testing distance5.49.011.1-3.2-3.03.13.1-3.23.13.23.13.22.63.13.1-3.1-3.13.1-3.13.13.2-3.33.1-2.42.11.8
Locomotor testing rearing0.20.30.7-0.6-0.60.60.6-0.60.60.70.50.6-0.00.60.6-0.6-0.60.6-0.70.60.7-0.80.80.20.2-0.1
Locomotion in novel chamber0.20.20.50.50.1-0.5-0.40.5-0.5-0.5-0.5-0.5-0.3-0.6-0.50.50.5-0.50.5-0.5-0.50.3-0.50.2-0.7-0.7
Locomotion in novel chamber post-restriction0.81.01.4-0.9-1.21.01.0-1.01.01.01.01.01.10.91.0-1.0-1.01.0-1.01.01.0-1.21.0-0.90.60.6
Fecal boli incidents, locomotor time 10.40.40.9-0.6-0.90.70.7-0.70.70.70.60.70.60.60.7-0.7-0.70.7-0.70.70.7-0.70.6-0.60.40.4
Change in fecal boli incidents, locomotor task0.00.00.1-0.2-0.30.10.1-0.10.10.10.10.10.30.10.1-0.1-0.10.1-0.20.10.1-0.10.2-0.20.10.2
Time >=10cm from walls, locomotor time 10.10.10.20.30.4-0.3-0.40.4-0.4-0.4-0.3-0.4-0.2-0.3-0.40.30.3-0.30.3-0.4-0.40.5-0.30.3-0.1-0.0
Bouts of movement, locomotor time 10.00.00.1-0.1-0.20.10.1-0.10.10.10.10.10.00.10.1-0.1-0.10.1-0.20.10.1-0.10.1-0.10.10.1
Total resting periods, locomotor time 10.00.00.1-0.1-0.30.10.1-0.10.10.10.10.1-0.00.10.1-0.1-0.10.1-0.20.10.1-0.10.1-0.10.10.1
Rest time, locomotor task time 10.50.60.70.80.6-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.80.8-0.80.7-0.8-0.80.6-0.90.8-0.7-0.7
Distance moved, locomotor task time 11.71.82.6-1.4-1.41.41.4-1.41.41.41.41.41.61.41.4-1.4-1.41.4-1.31.41.4-1.21.4-1.41.01.1
Vertical activity count, locomotor time 10.80.81.1-1.0-1.00.90.9-0.90.90.90.90.91.01.00.9-0.9-0.90.9-0.90.90.9-0.71.0-1.00.80.9
Time >=10cm from walls, locomotor time 21.51.61.8-1.3-1.31.31.3-1.31.31.31.31.31.31.31.3-1.3-1.31.3-1.31.31.3-1.21.3-1.11.01.0
Bouts of movement, locomotor time 20.00.00.1-0.1-0.10.10.1-0.10.10.10.10.1-0.10.10.1-0.1-0.10.1-0.10.10.1-0.20.0-0.0-0.2-0.3
Total resting periods, locomotor time 20.10.10.30.20.1-0.2-0.20.2-0.2-0.1-0.2-0.2-0.4-0.2-0.20.20.2-0.20.1-0.2-0.20.0-0.20.3-0.4-0.5
Rest time, locomotor task time 20.00.00.30.20.0-0.2-0.20.2-0.2-0.2-0.2-0.2-0.5-0.2-0.20.20.2-0.20.1-0.2-0.20.0-0.20.4-0.2-0.3
Distance moved, locomotor task time 21.01.22.1-1.1-1.01.11.1-1.11.11.01.11.01.51.11.1-1.0-1.01.0-1.01.01.0-0.81.1-1.21.01.1
Vertical activity count, locomotor time 20.10.10.2-0.3-0.20.30.3-0.30.30.20.30.30.40.30.3-0.3-0.30.3-0.20.30.2-0.10.3-0.40.20.3
Light reinforcement 10.71.31.5-1.2-1.11.11.1-1.11.11.11.21.11.21.21.1-1.1-1.11.1-1.11.11.1-0.91.0-1.11.21.2
Light reinforcement 20.10.10.30.10.5-0.3-0.30.3-0.3-0.3-0.2-0.3-0.3-0.3-0.30.30.3-0.30.3-0.3-0.40.5-0.3-0.1-0.10.1
Bone: marrow area0.10.20.4-0.4-0.30.40.4-0.50.50.50.40.50.20.50.4-0.5-0.50.5-0.50.50.5-0.50.60.10.30.2
Bone: maximum diameter0.40.80.90.90.7-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-0.90.90.9-0.90.9-0.9-0.90.8-0.80.6-1.0-0.9
Bone: maximum force0.71.21.4-1.1-1.21.11.1-1.11.11.11.11.11.01.11.1-1.1-1.11.1-1.11.11.1-1.11.2-0.90.90.9
Bone: maximum moment0.81.41.6-1.2-1.31.21.2-1.21.21.21.21.21.11.21.2-1.2-1.21.2-1.21.21.2-1.21.3-1.00.90.9
Mean time between licks in bursts1.11.62.21.31.3-1.3-1.21.2-1.3-1.3-1.3-1.3-1.2-1.3-1.31.31.3-1.31.3-1.3-1.21.1-1.11.2-1.5-1.5
Mean num. licks in bursts0.60.71.2-0.9-0.60.90.9-0.80.90.80.90.81.10.80.9-0.8-0.80.8-0.80.80.8-0.80.7-1.00.80.8
Cd content in liver2.22.43.4-1.4-1.81.51.6-1.61.61.61.51.61.41.61.6-1.6-1.61.6-1.61.61.6-1.51.8-0.91.51.3
Co content in liver0.00.00.1-0.10.10.10.1-0.10.10.10.10.1-0.30.10.1-0.1-0.10.1-0.10.10.1-0.20.30.2-0.1-0.2
Cu content in liver3.94.75.5-2.2-2.42.22.2-2.22.22.22.22.22.22.22.2-2.2-2.22.2-2.22.22.3-2.22.3-1.71.71.6
Fe content in liver1.61.92.7-1.1-1.61.31.3-1.31.41.41.31.41.31.51.4-1.4-1.41.4-1.41.41.4-1.21.6-0.61.61.4
K content in liver0.80.81.5-1.0-0.90.90.9-0.90.90.90.90.91.20.80.9-0.9-0.80.8-0.80.80.8-1.00.7-1.20.50.6
Mg content in liver0.00.00.3-0.2-0.00.10.1-0.10.00.10.00.10.3-0.00.0-0.0-0.00.00.0-0.00.0-0.3-0.1-0.5-0.5-0.4
Mn content in liver0.70.81.3-1.1-0.60.90.9-0.90.90.90.90.91.00.80.9-0.9-0.90.9-0.90.80.9-1.10.8-1.10.20.3
Na content in liver0.30.40.9-0.5-0.50.50.6-0.60.60.60.60.60.50.70.6-0.6-0.60.6-0.60.60.6-0.40.6-0.10.90.9
Rb content in liver1.01.32.6-0.8-1.21.01.1-1.11.11.11.11.10.71.21.1-1.2-1.21.2-1.21.21.2-0.91.60.21.61.3
Se content in liver0.10.10.4-0.3-0.30.20.2-0.20.20.20.20.20.40.20.2-0.1-0.10.1-0.20.20.1-0.0-0.2-0.60.40.5
Sr content in liver0.10.10.6-0.3-0.00.20.1-0.10.10.10.10.10.3-0.00.1-0.1-0.10.1-0.00.00.0-0.3-0.1-0.8-0.5-0.4
Zn content in liver4.44.85.9-2.3-2.42.32.3-2.32.22.32.22.32.42.22.3-2.2-2.22.2-2.22.22.3-2.42.3-2.21.31.3
Bone: minimum diameter0.30.60.90.80.9-0.8-0.80.8-0.8-0.8-0.8-0.8-0.9-0.8-0.80.80.8-0.80.8-0.8-0.80.7-0.70.8-0.9-0.9
Time in familiar zone, hab. session 11.51.42.71.31.0-1.2-1.21.2-1.2-1.1-1.2-1.1-1.6-1.1-1.11.11.1-1.11.1-1.1-1.11.2-0.91.6-0.8-0.9
Time in novel zone, hab. session 10.60.61.1-0.9-0.70.80.8-0.80.80.80.80.80.80.80.8-0.8-0.80.7-0.80.70.7-0.70.6-1.10.80.9
Total zone transitions, hab. session 10.60.81.4-1.1-0.71.01.0-1.00.90.90.90.90.80.80.9-0.9-0.90.9-0.90.90.9-1.10.8-1.20.20.3
Total locomotion distance, hab. session 10.20.30.8-0.7-0.50.60.6-0.60.60.60.60.60.80.50.6-0.6-0.60.6-0.50.60.6-0.60.4-0.90.30.4
Locomotion velocity, hab. session 10.30.40.8-0.7-0.50.70.6-0.60.60.60.60.60.90.60.6-0.6-0.60.6-0.60.60.6-0.70.4-0.90.30.4
Time in familiar zone, hab. session 20.50.61.00.80.6-0.7-0.70.7-0.7-0.7-0.8-0.7-0.9-0.7-0.70.70.7-0.70.7-0.7-0.70.6-0.60.8-0.9-1.0
Time in novel zone, hab. session 20.00.00.1-0.1-0.00.20.2-0.20.20.20.20.20.00.20.2-0.2-0.20.2-0.20.20.2-0.10.2-0.00.30.3
Total zone transitions, hab. session 20.10.10.7-0.5-0.20.30.3-0.30.30.30.30.30.30.20.3-0.2-0.20.2-0.20.20.2-0.50.2-0.8-0.5-0.4
Total locomotion distance, hab. session 20.30.41.0-0.7-0.60.60.6-0.60.60.60.60.61.00.50.6-0.6-0.60.6-0.50.50.6-0.70.4-1.00.10.2
Locomotion velocity, hab. session 20.20.30.9-0.6-0.50.50.5-0.50.50.50.50.50.90.40.5-0.4-0.40.4-0.40.40.4-0.50.3-0.90.10.2
Novel to familiar place preference ratio0.80.81.0-0.9-0.60.90.9-1.00.90.90.91.01.00.90.9-0.9-0.90.9-0.90.90.9-0.91.0-0.60.60.5
Novelty place preference0.80.81.0-0.9-0.50.90.9-0.90.90.90.90.90.90.90.9-0.9-0.90.9-0.90.90.9-0.91.0-0.50.70.6
Time in novel zone, NPP test1.01.01.4-1.0-0.71.11.1-1.11.11.11.01.11.01.11.1-1.1-1.11.1-1.11.11.1-1.01.2-0.60.80.7
Total zone transitions, NPP test2.33.25.9-2.1-1.61.91.9-1.91.81.81.81.82.01.71.8-1.8-1.81.8-1.71.71.8-2.21.6-2.40.50.6
Total locomotion distance, NPP test1.01.42.8-1.3-1.21.21.2-1.21.21.21.21.21.51.11.2-1.1-1.11.1-1.11.11.1-1.30.9-1.70.50.7
Locomotion velocity, NPP test1.11.53.0-1.4-1.21.31.3-1.31.21.21.21.21.61.21.2-1.2-1.21.2-1.21.21.2-1.31.0-1.70.60.7
Intraocular pressure1.01.42.0-1.0-1.31.21.2-1.21.21.21.21.21.01.31.2-1.2-1.21.2-1.31.31.2-1.21.3-0.61.41.3
Delta distance traveled before/after self-admin0.20.20.70.40.5-0.4-0.40.4-0.4-0.4-0.4-0.4-0.5-0.4-0.40.40.4-0.40.6-0.5-0.40.8-0.30.5-0.3-0.2
Delta ambulatory time before/after self-admin0.20.20.4-0.6-0.40.50.5-0.50.50.60.50.50.30.60.5-0.5-0.50.5-0.40.50.5-0.00.6-0.20.50.5
Parametrial fat weight1.12.22.9-1.6-1.41.51.5-1.51.51.51.61.51.71.51.5-1.5-1.51.5-1.41.51.4-1.31.3-1.51.51.6
Pavlov. Cond. lever latency5.36.77.4-2.5-2.52.62.6-2.62.62.62.72.62.32.72.6-2.7-2.72.7-2.72.72.6-2.42.7-1.82.72.6
Pavlov. Cond. magazine entry latency6.68.59.13.02.8-3.0-3.03.0-3.0-3.0-3.0-3.0-2.9-3.0-3.03.03.0-3.03.0-3.0-3.02.7-2.92.4-2.9-2.8
Pavlov. Cond. change in total contacts1.81.92.21.51.3-1.4-1.41.4-1.4-1.4-1.5-1.4-1.3-1.4-1.41.41.4-1.41.4-1.4-1.41.3-1.31.3-1.4-1.4
Pavlov. Cond. index score6.68.49.02.92.8-2.9-2.92.9-3.0-2.9-3.0-2.9-2.8-3.0-2.93.03.0-3.03.0-3.0-2.92.7-2.92.3-2.9-2.8
Pavlov. Cond. latency score6.48.28.82.92.8-2.9-2.92.9-2.9-2.9-3.0-2.9-2.7-3.0-2.92.92.9-2.93.0-2.9-2.92.7-2.92.3-2.9-2.8
Pavlov. Cond. lever contacts3.13.74.61.91.8-1.9-1.91.9-2.0-1.9-2.0-1.9-1.6-2.0-1.92.02.0-2.02.0-2.0-2.01.7-2.01.2-2.2-2.0
Pavlov. Cond. magazine entry number7.69.510.2-3.2-3.03.13.1-3.13.23.13.23.13.13.23.1-3.1-3.13.1-3.23.23.1-2.93.0-2.73.02.9
Pavlov. Cond. intertrial magazine entries0.40.50.6-0.7-0.60.70.7-0.70.70.70.70.70.60.70.7-0.7-0.70.7-0.80.70.7-0.70.7-0.40.70.6
Pavlov. Cond. lever-magazine prob. diff.5.97.37.82.82.5-2.7-2.72.7-2.8-2.7-2.8-2.7-2.6-2.8-2.82.82.8-2.82.8-2.8-2.72.5-2.72.2-2.8-2.7
Pavlov. Cond. response bias7.28.79.43.02.8-3.0-3.03.0-3.0-3.0-3.1-3.0-2.8-3.1-3.03.03.0-3.03.1-3.0-3.02.8-3.02.4-2.9-2.8
Pavlov. Cond. lever latency0.40.60.90.90.8-0.8-0.80.8-0.8-0.8-0.7-0.8-0.8-0.7-0.80.80.8-0.80.7-0.8-0.81.0-0.80.8-0.1-0.0
Pavlov. Cond. magazine entry latency0.10.20.90.20.2-0.3-0.30.3-0.3-0.3-0.4-0.3-0.2-0.4-0.30.30.3-0.30.4-0.4-0.30.1-0.3-0.1-1.0-0.9
Pavlov. Cond. change in total contacts2.43.44.3-2.0-2.01.91.9-1.91.91.91.81.91.81.81.9-1.9-1.91.9-1.81.91.9-2.12.0-1.80.80.7
Pavlov. Cond. index score0.10.10.4-0.5-0.50.40.4-0.40.30.30.30.30.40.20.3-0.3-0.30.3-0.30.30.3-0.50.3-0.6-0.4-0.4
Pavlov. Cond. latency score0.10.10.3-0.4-0.40.30.3-0.30.30.30.20.30.30.20.2-0.2-0.20.2-0.20.20.2-0.50.2-0.6-0.5-0.4
Pavlov. Cond. lever contacts1.01.41.8-1.3-1.21.21.2-1.21.21.21.21.21.21.11.2-1.2-1.21.2-1.21.21.2-1.31.2-1.20.40.4
Pavlov. Cond. magazine entry number0.40.51.7-0.5-0.50.60.6-0.60.60.60.70.60.50.70.6-0.6-0.60.6-0.70.70.6-0.40.5-0.31.31.3
Pavlov. Cond. intertrial magazine entries0.40.51.50.90.8-0.8-0.70.7-0.7-0.7-0.7-0.7-1.0-0.6-0.70.70.7-0.70.7-0.7-0.70.8-0.51.2-0.2-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.4-0.40.30.3-0.30.30.30.20.30.40.20.3-0.3-0.30.3-0.20.30.3-0.50.3-0.6-0.5-0.5
Pavlov. Cond. response bias0.10.10.3-0.4-0.40.30.3-0.30.30.30.20.30.40.20.3-0.3-0.30.3-0.20.30.3-0.50.3-0.5-0.6-0.5
Time in closed arm before self-admin1.71.93.5-1.3-1.41.41.4-1.41.41.41.41.41.31.31.4-1.4-1.41.4-1.51.41.4-1.91.4-1.40.90.8
Time in closed arm after self-admin0.00.00.2-0.1-0.40.10.1-0.10.10.10.10.10.20.10.1-0.1-0.10.1-0.20.10.1-0.40.1-0.1-0.1-0.1
Time in open arm before self-admin1.21.32.11.11.1-1.2-1.21.2-1.2-1.2-1.1-1.2-1.0-1.1-1.21.21.2-1.21.2-1.2-1.21.5-1.31.1-0.8-0.8
Time in open arm after self-admin0.20.20.90.40.9-0.4-0.40.4-0.4-0.4-0.4-0.4-0.5-0.4-0.40.40.4-0.40.5-0.4-0.40.6-0.50.4-0.3-0.3
Bone: periosteal estimation0.00.00.1-0.1-0.10.10.1-0.10.10.20.10.1-0.00.10.1-0.1-0.10.1-0.20.10.2-0.20.30.1-0.0-0.1
Bone: periosteal perimeter1.22.02.11.41.5-1.4-1.41.4-1.4-1.4-1.5-1.4-1.4-1.4-1.41.41.4-1.41.4-1.4-1.41.4-1.31.3-1.4-1.3
Bone: post-yield work0.00.00.1-0.2-0.10.20.2-0.20.20.20.20.20.20.20.2-0.2-0.20.2-0.20.20.2-0.20.3-0.10.10.1
Progressive ratio test 1 active lever presses0.00.00.20.10.2-0.1-0.00.0-0.1-0.1-0.1-0.0-0.2-0.1-0.10.00.0-0.00.0-0.1-0.0-0.3-0.20.3-0.4-0.5
Progressive ratio test 1 breakpoint0.10.10.20.20.3-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.20.2-0.20.1-0.2-0.1-0.2-0.20.3-0.4-0.5
Progressive ratio test 1 inactive lever presses0.40.40.70.70.4-0.7-0.60.6-0.7-0.7-0.7-0.6-0.8-0.7-0.70.60.6-0.60.6-0.6-0.60.3-0.70.6-0.7-0.8
Progressive ratio test 2 active lever presses1.01.01.41.01.1-1.0-1.01.0-1.0-1.0-1.1-1.0-1.0-1.1-1.01.01.0-1.01.0-1.0-1.00.7-1.11.0-1.2-1.2
Progressive ratio test 2 breakpoint0.80.91.21.01.0-0.9-0.90.9-0.9-0.9-1.0-0.9-0.8-1.0-0.90.90.9-0.90.9-0.9-0.90.7-1.00.8-1.1-1.1
Progressive ratio test 2 inactive lever presses2.12.43.31.61.5-1.6-1.51.5-1.6-1.6-1.6-1.5-1.6-1.7-1.61.61.6-1.61.6-1.6-1.51.1-1.61.3-1.8-1.8
Incentive Sensitization - Responses1.71.71.91.31.3-1.4-1.41.4-1.4-1.3-1.3-1.4-1.2-1.3-1.41.41.4-1.41.4-1.4-1.41.4-1.41.2-1.1-1.1
Incentive Sensitization - Breakpoint1.71.71.91.31.3-1.3-1.31.3-1.3-1.3-1.3-1.3-1.2-1.3-1.31.31.3-1.31.4-1.3-1.31.3-1.41.1-1.1-1.1
Sum of active levers in priming session hrs 5-60.50.50.7-0.7-0.60.70.7-0.70.70.70.70.70.80.70.7-0.7-0.70.7-0.70.70.7-0.70.7-0.70.80.8
Progressive ratio3.33.84.6-2.0-2.12.02.0-2.02.02.02.02.02.01.92.0-2.0-2.02.0-2.02.02.0-2.22.0-1.71.41.3
Food seeking constrained by brief footshock0.70.91.31.01.1-0.9-0.90.9-1.0-1.0-1.0-1.0-0.8-1.0-0.91.01.0-1.01.0-1.0-1.00.9-1.00.7-1.1-1.0
Seeking ratio, punishment vs. effort5.36.57.42.62.7-2.6-2.62.6-2.6-2.6-2.6-2.6-2.4-2.6-2.62.62.6-2.62.6-2.6-2.62.6-2.62.1-2.2-2.1
Retroperitoneal fat weight0.62.02.4-1.5-1.41.51.4-1.41.51.41.51.41.51.51.4-1.4-1.41.4-1.31.41.4-1.11.4-1.61.41.5
Reaction time number correct0.30.51.10.70.7-0.7-0.70.7-0.7-0.7-0.7-0.7-1.1-0.6-0.70.70.7-0.70.7-0.7-0.60.6-0.50.9-0.6-0.6
Reaction time mean minus median0.00.10.2-0.4-0.30.20.2-0.20.20.20.30.20.30.20.2-0.2-0.20.2-0.30.20.2-0.30.0-0.50.10.2
Reaction time mean minus median AUC0.20.30.4-0.6-0.60.50.5-0.50.50.50.50.50.50.50.5-0.5-0.50.5-0.60.50.5-0.60.3-0.60.40.4
Reaction time num false alarms0.30.40.80.70.8-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.60.6-0.60.6-0.6-0.60.6-0.50.9-0.4-0.5
Reaction time num false alarms AUC0.10.10.30.30.5-0.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.2-0.30.30.3-0.30.3-0.3-0.30.4-0.20.50.10.0
Reaction time trials correct on left0.30.51.10.70.7-0.7-0.70.7-0.7-0.7-0.7-0.7-1.1-0.6-0.70.70.7-0.70.7-0.7-0.60.6-0.50.9-0.6-0.6
Reaction time trials on left0.40.51.20.80.8-0.7-0.70.7-0.7-0.7-0.7-0.7-1.1-0.7-0.70.70.7-0.70.7-0.7-0.70.7-0.60.9-0.6-0.7
Reaction time mean0.00.00.0-0.1-0.10.10.1-0.10.10.10.10.10.00.10.1-0.1-0.10.1-0.20.10.1-0.1-0.10.0-0.0-0.1
Reaction time mean AUC0.00.00.0-0.00.0-0.00.0-0.0-0.00.0-0.00.0-0.00.00.0-0.0-0.00.0-0.10.00.0-0.0-0.10.1-0.0-0.1
Median of all reaction times0.00.00.0-0.0-0.10.10.1-0.10.10.10.10.1-0.20.10.1-0.1-0.10.1-0.10.10.10.0-0.00.20.1-0.0
Reaction time omissions0.30.40.80.80.5-0.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.5-0.60.60.6-0.60.6-0.6-0.60.9-0.60.90.10.0
Reaction time false alarm rate0.00.00.10.20.3-0.2-0.20.2-0.2-0.1-0.1-0.20.1-0.1-0.20.10.1-0.10.1-0.1-0.20.3-0.10.30.10.1
Reaction time premature initiation rate2.12.83.2-1.7-1.71.71.7-1.71.71.71.71.71.81.81.7-1.7-1.71.7-1.61.71.7-1.31.5-1.61.71.8
Reaction time premature initiations0.91.31.7-1.2-1.11.21.2-1.21.21.21.21.21.11.31.1-1.2-1.21.2-1.11.21.2-0.81.1-1.11.31.3
Std. dev. reaction times0.10.10.2-0.4-0.30.40.4-0.40.30.40.30.40.30.30.4-0.4-0.40.4-0.40.30.4-0.40.1-0.30.20.1
Reaction time trials completed0.40.51.20.80.8-0.7-0.70.7-0.7-0.7-0.7-0.7-1.1-0.7-0.70.70.7-0.70.7-0.7-0.70.7-0.60.9-0.6-0.7
Reaction time trials AUC0.50.71.40.90.9-0.8-0.80.8-0.8-0.8-0.8-0.8-1.2-0.8-0.80.80.8-0.80.8-0.8-0.80.7-0.71.0-0.7-0.8
Run reversals in cocaine runway, females1.81.72.31.31.4-1.3-1.31.3-1.3-1.3-1.3-1.4-1.4-1.3-1.31.31.3-1.31.4-1.3-1.41.5-1.50.9-0.8-0.7
Run reversals in cocaine runway, males0.60.50.9-0.8-0.90.70.7-0.70.70.70.80.70.60.80.7-0.7-0.70.7-0.60.70.7-0.20.9-0.80.70.8
Latency to leave start box in cocaine runway0.40.41.0-0.6-0.90.60.6-0.60.60.60.60.61.00.60.6-0.6-0.60.6-0.50.60.6-0.30.7-0.80.50.6
Latency to leave start box in cocaine runway, F1.41.52.1-1.2-1.41.21.2-1.21.21.21.21.21.41.21.2-1.2-1.21.2-1.21.21.2-1.11.4-1.40.80.8
Latency to leave start box in cocaine runway, M0.30.30.60.60.4-0.6-0.60.6-0.6-0.6-0.5-0.6-0.2-0.5-0.60.60.6-0.60.7-0.6-0.60.8-0.60.4-0.2-0.1
Std. dev. time between licks in bursts4.04.86.32.22.0-2.2-2.22.2-2.2-2.2-2.3-2.2-2.5-2.2-2.22.22.2-2.22.2-2.2-2.11.9-1.92.2-2.4-2.5
Total sessions with >9 infusions0.10.10.30.2-0.1-0.2-0.20.2-0.3-0.2-0.3-0.2-0.2-0.2-0.30.20.2-0.20.2-0.2-0.20.2-0.30.4-0.5-0.6
Short access day 1 total inactive lever presses3.64.05.32.01.8-2.0-2.02.0-2.0-2.0-2.1-2.0-2.0-2.1-2.02.02.0-2.01.9-2.0-2.01.5-2.02.0-2.2-2.3
Short access day 10 total inactive lever presses0.00.00.00.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.2-0.1-0.10.10.1-0.10.1-0.1-0.10.20.0-0.00.10.1
Short access day 1 total infusions0.90.91.01.00.8-1.0-1.01.0-1.0-1.0-1.0-1.0-0.8-1.0-1.01.01.0-1.00.9-1.0-1.00.9-1.01.0-0.9-0.9
Short access day 10 total infusions0.10.10.60.20.3-0.2-0.20.2-0.2-0.2-0.3-0.2-0.3-0.3-0.20.20.2-0.20.2-0.2-0.2-0.1-0.30.3-0.7-0.8
Short access total infusions0.50.61.00.80.8-0.7-0.70.7-0.8-0.7-0.8-0.7-0.7-0.8-0.70.70.7-0.70.7-0.7-0.70.5-0.80.8-1.0-1.0
Short access day 1 locomotion0.10.10.20.30.1-0.2-0.20.2-0.2-0.2-0.3-0.2-0.3-0.2-0.20.20.2-0.20.2-0.2-0.20.1-0.30.2-0.4-0.4
Short access day 10 total locomotion0.00.00.1-0.2-0.10.20.2-0.20.10.10.10.20.10.10.2-0.2-0.20.2-0.20.20.2-0.30.1-0.1-0.1-0.1
Short access total locomotion0.00.00.20.10.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.1-0.1-0.1-0.20.1-0.4-0.4
One hour access (0.3 mA shock)0.20.20.80.40.7-0.4-0.30.3-0.4-0.3-0.4-0.3-0.5-0.4-0.40.30.3-0.30.3-0.3-0.30.0-0.50.6-0.8-0.9
Compulsive drug intake0.00.00.10.10.3-0.1-0.10.1-0.1-0.1-0.0-0.1-0.2-0.0-0.10.10.1-0.10.1-0.1-0.10.20.00.30.20.2
One hour access (shock baseline)0.10.10.80.30.4-0.2-0.20.2-0.2-0.2-0.3-0.2-0.4-0.3-0.20.20.2-0.20.2-0.2-0.2-0.2-0.40.3-0.8-0.9
Social response proportion0.50.51.5-0.6-0.60.70.7-0.70.70.70.80.70.50.80.7-0.7-0.70.7-0.70.70.7-0.40.7-0.41.21.2
Social responses0.30.40.5-0.7-0.60.70.7-0.70.70.70.70.70.50.70.7-0.7-0.70.7-0.70.70.7-0.70.6-0.50.70.7
Social time0.40.61.00.70.9-0.8-0.80.8-0.8-0.8-0.7-0.8-1.0-0.7-0.80.80.8-0.80.8-0.8-0.81.0-0.90.4-0.2-0.0
Soleus weight3.911.313.1-3.5-3.63.53.5-3.53.43.53.43.43.53.43.4-3.4-3.43.4-3.43.43.4-3.63.4-3.42.32.3
Bone: stiffness0.10.20.4-0.4-0.40.40.4-0.40.50.50.50.50.40.50.5-0.5-0.50.5-0.50.50.5-0.40.5-0.20.60.5
Tibialis anterior weight0.00.00.1-0.2-0.30.20.2-0.20.20.20.10.20.30.10.2-0.2-0.10.2-0.20.10.2-0.20.1-0.3-0.1-0.1
Time to tail flick, vehicle, before self-admin2.12.13.3-1.4-1.81.41.4-1.41.41.41.41.41.61.41.4-1.4-1.41.4-1.51.41.4-1.61.5-1.31.31.2
Time to tail flick, vehicle, after self-admin0.60.61.0-0.8-0.70.80.8-0.80.80.70.80.80.90.80.8-0.8-0.80.8-0.70.80.7-0.70.9-1.00.70.7
Time to tail flick, test, before self-admin0.10.10.6-0.20.00.20.2-0.20.20.20.30.10.40.30.2-0.2-0.20.1-0.00.20.10.30.3-0.20.60.7
Time to tail flick, test, after self-admin0.10.10.30.40.2-0.4-0.40.4-0.4-0.4-0.4-0.4-0.2-0.4-0.40.40.4-0.40.4-0.4-0.40.3-0.50.2-0.4-0.3
Delta time to tail flick, vehicle, before/after SA0.50.50.70.70.9-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.70.7-0.70.8-0.7-0.70.8-0.60.5-0.7-0.6
Delta time to tail flick, test, before/after SA0.30.30.80.60.3-0.5-0.50.5-0.5-0.5-0.6-0.5-0.6-0.6-0.50.50.5-0.50.4-0.5-0.50.1-0.60.6-0.8-0.9
Tibia length6.819.322.5-4.7-4.54.64.5-4.54.54.54.54.54.64.44.5-4.4-4.44.4-4.44.44.4-4.74.2-4.72.92.9
Ambulatory time before self-admin0.10.10.40.20.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.6-0.3-0.20.20.2-0.20.1-0.2-0.2-0.2-0.10.3-0.2-0.3
Ambulatory time after self-admin0.00.00.10.10.3-0.1-0.10.1-0.1-0.1-0.1-0.1-0.3-0.1-0.10.10.1-0.10.1-0.1-0.10.20.10.2-0.0-0.1
Bone: tissue strength3.02.93.7-1.7-1.91.81.8-1.81.81.81.71.81.51.81.8-1.8-1.81.8-1.81.81.8-1.81.8-1.41.31.2
Total heroin consumption1.21.41.7-1.3-1.31.21.2-1.21.21.21.21.20.91.21.2-1.2-1.21.2-1.21.21.2-1.01.3-0.91.01.0
Bone: trabecular number0.60.91.70.91.3-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-1.0-0.90.90.9-0.90.9-0.9-0.90.8-1.00.8-0.9-0.9
Bone: trabecular spacing1.41.82.7-1.3-1.71.31.3-1.31.31.31.41.31.21.41.3-1.3-1.31.3-1.41.41.3-1.21.3-1.21.41.4
Bone: trabecular thickness0.00.00.2-0.30.00.20.2-0.20.20.20.20.20.40.10.2-0.1-0.10.1-0.10.10.1-0.20.0-0.4-0.00.1
Bone: trabecular tissue density0.20.30.4-0.6-0.50.60.6-0.60.60.60.60.60.60.60.6-0.6-0.60.6-0.60.60.6-0.50.5-0.50.60.6
Water consumed over 24 hours0.00.00.10.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.0-0.1-0.10.10.1-0.10.1-0.1-0.10.0-0.1-0.3-0.3-0.2
Number of responses in last shaping day0.70.81.20.90.8-0.9-0.90.9-0.9-0.9-0.9-0.9-1.1-0.9-0.90.90.9-0.90.8-0.9-0.90.7-0.90.9-0.9-0.9