Hub : Genes

Nbeal2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Nbeal2 0.14 0.1 8.1e-10 0.08 0.08 0.07 0.07 3.0e-09 4.0e-09 1.3e-08 1.1e-08
2 Brain gene expression Nbeal2 0.61 0.19 0.0e+00 0.32 0.32 0.32 0.32 6.2e-30 7.6e-31 8.4e-31 1.3e-30
3 Adipose isoform ratio XM_039082643.2 0.05 0.04 2.4e-05 0.03 0.03 0.04 0.03 1.1e-04 1.1e-04 9.1e-05 2.5e-04
4 NAcc intron excision ratio chr8_119485808_119485895 0.03 0.06 8.2e-04 0.01 0.01 0.01 0.01 3.2e-03 9.3e-03 1.2e-02 7.8e-03
5 NAcc mRNA stability Nbeal2 0.07 0.07 1.0e-09 0.06 0.06 0.06 0.06 4.4e-10 1.4e-09 1.9e-09 1.6e-09
6 Adipose gene expression Nbeal2 0.33 0.15 0.0e+00 0.23 0.26 0.25 0.25 1.0e-25 2.7e-28 1.5e-27 1.3e-27
7 Liver gene expression Nbeal2 0.27 0.13 0.0e+00 0.26 0.29 0.28 0.29 2.9e-28 3.3e-32 5.4e-31 5.6e-32
8 OFC gene expression Nbeal2 0.22 0.17 1.1e-03 0.08 0.08 0.06 0.08 6.3e-03 5.5e-03 1.3e-02 7.0e-03
9 BLA mRNA stability Nbeal2 0.12 0.11 3.8e-05 0.06 0.07 0.07 0.07 2.6e-04 8.3e-05 1.6e-04 8.3e-05
10 PL gene expression Nbeal2 0.17 0.11 0.0e+00 0.16 0.16 0.16 0.16 9.6e-17 3.4e-17 6.6e-17 1.6e-17
11 PL mRNA stability Nbeal2 0.08 0.08 4.9e-07 0.04 0.05 0.05 0.04 2.1e-05 5.7e-06 8.6e-06 1.0e-05
12 Adipose alternative TSS XM_006244008.5 0.07 0.05 5.3e-09 0.05 0.07 0.06 0.06 1.9e-06 2.4e-08 6.2e-07 3.0e-07
13 Adipose alternative TSS XM_006244008.5 0.07 0.05 4.5e-09 0.05 0.07 0.06 0.06 1.7e-06 2.1e-08 5.7e-07 2.7e-07
14 Adipose alternative TSS XM_003750591.6 0.07 0.05 4.2e-09 0.05 0.07 0.06 0.06 1.3e-06 2.0e-08 3.0e-07 2.1e-07
15 IC gene expression Nbeal2 0.28 0.17 1.2e-11 0.23 0.25 0.23 0.24 3.3e-10 4.7e-11 3.7e-10 1.6e-10
16 Adipose alternative TSS XM_039082645.2 0.07 0.05 4.2e-09 0.05 0.07 0.06 0.06 1.3e-06 2.0e-08 1.5e-07 2.2e-07
17 NAcc gene expression Nbeal2 0.18 0.1 0.0e+00 0.2 0.22 0.21 0.22 7.0e-29 7.3e-33 3.5e-31 6.5e-32
18 Liver mRNA stability Nbeal2 0.03 0.02 6.5e-04 0 0.01 0 0.01 7.3e-02 3.4e-02 1.3e-01 6.1e-02
19 IL gene expression Nbeal2 0.89 0.08 3.0e-05 0.1 0.09 0.09 0.14 2.2e-03 3.3e-03 3.0e-03 3.1e-04
20 pVTA gene expression Nbeal2 0.1 0.12 3.5e-05 0.04 0.03 0.03 0.03 7.1e-04 2.4e-03 2.4e-03 2.8e-03
21 BLA gene expression Nbeal2 0.4 0.24 0.0e+00 0.31 0.3 0.31 0.3 4.6e-17 3.6e-16 6.8e-17 4.5e-16
22 Brain mRNA stability Nbeal2 0.15 0.11 7.2e-12 0.12 0.12 0.13 0.12 1.3e-11 1.1e-11 9.6e-12 1.2e-11
23 pVTA mRNA stability Nbeal2 0.05 0.05 2.4e-04 0.04 0.04 0.04 0.04 6.4e-04 2.3e-04 2.1e-04 5.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.00.00.10.00.0-0.00.10.10.00.00.00.00.10.0-0.0-0.00.00.00.00.00.00.10.0-0.30.0-0.1
Area under the delay curve1.72.02.2-1.5-1.51.5-1.4-1.4-1.5-1.5-1.5-1.5-1.2-1.51.51.5-1.5-1.5-1.5-1.4-1.5-1.4-1.4-1.3-1.3-1.0
BMI with tail0.10.41.10.80.9-0.70.50.50.60.60.50.50.50.4-0.5-0.50.50.50.50.50.50.90.60.30.61.1
BMI without tail0.61.72.51.41.6-1.31.41.41.31.31.31.31.41.2-1.3-1.31.21.31.21.21.21.41.01.21.31.3
Body weight5.222.927.25.15.2-5.04.84.84.94.94.84.84.84.7-4.8-4.84.84.84.84.74.84.84.84.74.64.1
Weight adjusted by age0.00.00.20.10.00.0-0.0-0.00.00.00.00.00.00.0-0.0-0.00.00.00.00.00.0-0.10.10.40.0-0.2
Bone surface0.10.20.2-0.4-0.40.4-0.4-0.4-0.4-0.4-0.5-0.5-0.4-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.4-0.4-0.5
Bone volume0.00.10.1-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.30.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2-0.3
Breakpoint value in progressive ratio session0.10.10.3-0.4-0.40.4-0.3-0.3-0.4-0.4-0.4-0.4-0.3-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.3-0.4-0.6-0.40.2
Number of licking bursts0.10.20.4-0.5-0.50.5-0.6-0.6-0.5-0.5-0.5-0.5-0.6-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.6-0.3-0.5-0.5-0.1
Context. condit. distance diff. score0.00.00.20.10.0-0.0-0.1-0.1-0.0-0.0-0.0-0.0-0.1-0.00.00.0-0.0-0.0-0.0-0.0-0.00.10.0-0.50.00.0
Locomotion velocity, session 10.10.10.2-0.2-0.20.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.0-0.2-0.5-0.3-0.1
Locomotion distance, session 10.81.01.71.21.3-1.11.11.11.01.01.01.01.10.9-1.0-1.01.01.01.00.91.01.30.90.90.90.8
Locomotion velocity, session 20.30.40.5-0.4-0.40.5-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.4-0.7-0.7-0.6-0.3
Locomotion distance, session 20.00.00.10.20.1-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.1-0.30.20.2-0.2-0.2-0.2-0.2-0.20.1-0.1-0.1-0.3-0.0
Locomotion velocity, session 30.10.10.40.50.6-0.30.50.50.30.30.30.30.50.3-0.3-0.30.30.30.30.30.30.50.10.00.40.5
Locomotion distance, session 30.70.81.6-0.7-0.70.8-0.7-0.7-0.9-0.9-0.9-0.9-0.7-1.01.01.0-1.0-1.0-1.0-1.0-1.0-0.8-1.0-1.3-0.8-0.3
Stereotopy head waving bouts, day 30.00.00.40.10.1-0.10.00.00.10.10.10.10.00.1-0.1-0.10.10.10.10.10.10.00.30.70.10.1
Stereotopy head waving duration, day 30.20.20.50.40.4-0.50.30.30.50.50.50.50.30.5-0.5-0.50.50.50.50.50.50.30.70.70.40.2
Locomotion velocity, session 70.40.40.60.80.7-0.70.70.70.60.70.70.70.70.6-0.7-0.70.70.60.70.70.70.20.60.20.60.1
Locomotion distance, session 70.40.51.5-0.5-0.60.6-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7-0.7-1.1-0.7-1.2-0.7-0.7
Stereotopy head waving bouts, day 70.00.00.1-0.2-0.20.3-0.1-0.1-0.2-0.2-0.2-0.2-0.1-0.10.20.2-0.2-0.2-0.2-0.2-0.20.1-0.30.2-0.2-0.0
Stereotopy head waving duration, day 70.20.30.60.50.5-0.40.60.60.50.50.50.50.60.5-0.5-0.50.50.50.50.50.50.70.30.50.50.6
Locomotion velocity, session 80.30.30.70.70.8-0.60.70.70.60.50.50.50.70.4-0.5-0.50.50.50.50.50.50.80.40.20.50.7
Locomotion distance, session 80.20.30.70.80.8-0.70.60.60.50.50.50.40.60.3-0.4-0.40.40.40.40.40.40.80.4-0.20.40.4
Degree of sensitization distance1.31.31.71.21.0-1.21.11.11.21.21.21.21.11.3-1.2-1.21.21.21.21.21.20.81.31.21.10.4
Degree of sensitization stereotypy0.00.00.1-0.0-0.00.10.20.20.00.00.00.00.20.1-0.0-0.00.00.00.00.0-0.00.4-0.20.30.10.1
Conditioned locomotion3.33.84.5-2.1-2.12.1-2.0-2.0-2.0-2.0-2.0-2.0-1.9-1.92.02.0-2.0-2.0-2.0-1.9-2.0-1.9-2.0-1.8-1.8-1.6
Cocaine response after cond. corrected0.20.30.40.50.5-0.60.50.50.50.50.50.50.50.5-0.5-0.50.50.50.50.50.50.40.60.60.50.4
Cocaine response after cond. not corrected1.61.92.61.51.4-1.51.41.41.41.41.41.41.31.4-1.4-1.41.41.41.41.41.41.31.41.61.31.0
Cocaine response before conditioning1.11.41.81.31.3-1.21.31.31.21.21.21.21.21.1-1.1-1.11.11.11.11.11.11.21.11.11.10.9
Saline control response0.71.02.10.90.9-1.00.90.91.01.01.01.01.01.1-1.0-1.01.01.01.01.01.00.81.01.40.90.0
Bone: connectivity density0.30.51.4-0.8-0.80.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.6-0.7-1.2-0.7-0.7
Bone: cortical apparent density0.20.30.5-0.6-0.50.6-0.4-0.4-0.6-0.6-0.6-0.6-0.6-0.50.60.6-0.6-0.6-0.6-0.5-0.6-0.3-0.6-0.7-0.5-0.3
Bone: cortical area0.10.20.3-0.4-0.40.3-0.6-0.6-0.4-0.4-0.4-0.4-0.5-0.50.40.4-0.4-0.4-0.4-0.4-0.4-0.6-0.30.3-0.5-0.5
Bone: cortical porosity0.10.10.2-0.5-0.50.4-0.4-0.4-0.4-0.3-0.3-0.3-0.4-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.4-0.2-0.4-0.4-0.3
Bone: cortical porosity0.10.10.2-0.4-0.40.3-0.4-0.4-0.3-0.3-0.2-0.2-0.3-0.20.20.2-0.2-0.2-0.2-0.2-0.2-0.4-0.1-0.3-0.3-0.3
Bone: cortical thickness0.10.21.70.40.4-0.40.30.30.40.40.40.40.30.3-0.4-0.40.40.40.40.40.40.20.41.30.30.0
Bone: cortical thickness0.00.00.00.10.0-0.1-0.0-0.00.00.00.00.0-0.00.0-0.0-0.00.00.00.00.00.0-0.20.00.1-0.0-0.1
Bone: cortical tissue density0.20.30.5-0.6-0.50.6-0.4-0.4-0.5-0.5-0.5-0.5-0.6-0.50.50.5-0.5-0.5-0.5-0.5-0.6-0.3-0.6-0.7-0.5-0.3
Condit. Reinf. active minus inactive responses0.10.10.20.30.2-0.30.30.30.40.40.40.40.30.4-0.4-0.40.40.40.40.40.40.10.40.30.40.0
Condit. Reinf. active-inactive response ratio0.30.30.40.50.4-0.60.40.40.60.60.60.60.40.6-0.6-0.60.60.60.60.60.60.30.60.50.60.2
Condit. Reinf. active responses0.00.00.1-0.3-0.20.3-0.0-0.0-0.1-0.1-0.1-0.1-0.0-0.00.10.1-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.30.0-0.1
Condit. Reinf. inactive responses0.60.81.2-1.0-0.81.1-0.7-0.7-0.9-0.9-0.9-0.9-0.7-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.7-1.1-0.9-0.8-0.4
Incentive salience index mean0.00.00.1-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2
Condit. Reinf. lever presses1.41.92.3-1.3-1.31.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.51.41.4-1.4-1.4-1.4-1.4-1.4-1.2-1.4-1.5-1.4-1.0
Condit. Reinf. active minus inactive responses1.72.23.61.61.6-1.61.51.51.51.51.51.51.41.4-1.5-1.51.51.51.51.51.51.41.41.91.41.1
Condit. Reinf. active-inactive response ratio1.61.82.91.41.5-1.31.41.41.41.41.31.31.41.3-1.3-1.31.31.31.31.31.31.31.21.71.31.1
Condit. Reinf. active responses1.41.93.21.41.4-1.41.31.31.41.41.41.41.31.4-1.4-1.41.41.41.41.41.41.41.31.81.31.0
Condit. Reinf. inactive responses0.10.10.2-0.4-0.40.3-0.5-0.5-0.3-0.3-0.3-0.3-0.5-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.4-0.4-0.2
Condit. Reinf. lever presses2.33.23.81.92.0-1.91.81.81.81.81.81.81.81.7-1.8-1.81.81.81.81.81.81.71.71.91.71.4
Condit. Reinf. lever reinforcers received1.72.43.91.61.6-1.61.51.51.61.61.61.61.41.5-1.6-1.61.61.61.61.51.61.51.52.01.41.1
Conditioned reinforcement - actives1.83.03.9-1.9-1.71.9-1.9-1.9-1.7-1.7-1.7-1.7-1.9-1.91.71.7-1.7-1.7-1.7-1.8-1.7-1.8-1.1-2.0-1.8-0.8
Conditioned reinforcement - inactives1.82.63.3-1.7-1.61.7-1.6-1.6-1.7-1.6-1.6-1.7-1.7-1.71.71.7-1.7-1.6-1.7-1.7-1.6-1.8-1.4-0.9-1.6-1.4
Conditioned locomotion0.40.50.8-0.8-0.70.8-0.9-0.9-0.7-0.7-0.7-0.7-0.8-0.80.70.7-0.7-0.7-0.7-0.7-0.7-0.6-0.4-0.7-0.8-0.2
Patch foraging indifference point 0 sec0.91.62.01.41.2-1.41.11.11.31.31.31.31.01.3-1.3-1.31.31.31.31.31.41.31.40.81.10.8
Patch foraging indifference point AUC0.00.00.10.00.2-0.00.30.30.10.10.10.10.30.1-0.1-0.10.10.10.10.10.10.20.20.30.20.4
Delay disc. indifference point, 0s delay0.00.00.1-0.1-0.00.0-0.0-0.0-0.0-0.0-0.0-0.00.2-0.10.00.0-0.0-0.0-0.0-0.0-0.0-0.10.30.2-0.00.0
Delay disc. indifference point, 16s delay0.91.01.3-1.0-1.01.0-0.9-0.9-1.1-1.1-1.1-1.1-0.8-1.01.11.1-1.1-1.1-1.1-1.1-1.1-0.9-1.1-1.1-0.9-0.8
Delay disc. indifference point, 2s delay0.30.30.5-0.7-0.60.7-0.6-0.6-0.6-0.6-0.6-0.6-0.4-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.5-0.4-0.4-0.5-0.4
Delay disc. indifference point, 24s delay0.91.01.4-1.0-1.01.0-1.0-1.0-1.1-1.1-1.1-1.0-0.8-1.01.01.0-1.0-1.0-1.0-1.0-1.1-1.0-1.0-1.2-0.9-0.7
Delay disc. indifference point, 4s delay1.81.92.2-1.5-1.41.5-1.4-1.4-1.4-1.4-1.4-1.4-1.2-1.41.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.3-1.2-1.3-1.0
Delay disc. indifference point, 8s delay1.92.22.4-1.6-1.51.6-1.5-1.5-1.5-1.5-1.5-1.5-1.4-1.51.51.5-1.5-1.5-1.5-1.5-1.5-1.4-1.4-1.5-1.4-1.1
Indifference point function ln k0.20.30.7-0.2-0.30.3-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.4-0.6-0.9-0.6-0.5
Indifference point function log k0.20.30.7-0.2-0.30.3-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.4-0.6-0.9-0.6-0.5
Patch foraging total patch changes 0 sec0.91.72.41.51.3-1.51.11.11.41.41.41.41.01.4-1.4-1.41.41.41.41.41.41.31.50.91.20.8
Patch foraging total patch changes 12 sec0.81.11.31.11.0-1.20.90.91.11.11.11.10.91.1-1.1-1.11.11.11.11.11.11.01.01.01.10.6
Patch foraging total patch changes 18 sec2.03.04.51.61.6-1.71.71.71.81.81.81.81.51.8-1.8-1.81.81.81.81.81.91.42.11.71.51.4
Patch foraging total patch changes 24 sec2.13.64.22.12.0-2.01.81.82.01.91.91.91.81.9-1.9-1.91.91.91.91.91.91.81.91.71.81.4
Patch foraging total patch changes 6 sec0.10.20.30.50.4-0.50.20.20.40.40.40.40.30.5-0.4-0.40.40.40.40.40.40.50.30.10.40.2
Patch foraging time to switch 0 sec0.20.30.5-0.6-0.70.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.50.60.6-0.6-0.6-0.6-0.6-0.6-0.7-0.7-0.5-0.5-0.4
Patch foraging water rate 0 sec0.20.30.70.60.6-0.70.40.40.60.60.60.60.40.5-0.6-0.60.60.60.60.50.60.50.80.90.50.1
Patch foraging water rate 12 sec0.20.50.91.00.8-0.90.60.60.70.70.70.70.50.7-0.7-0.70.70.70.70.70.70.60.50.80.70.4
Patch foraging water rate 18 sec0.10.10.50.60.6-0.50.40.40.30.30.30.30.40.2-0.3-0.30.30.30.30.30.30.30.10.70.4-0.0
Patch foraging water rate 24 sec0.71.01.71.01.0-1.00.90.91.01.01.01.01.01.0-1.0-1.01.01.01.01.01.01.00.91.31.00.6
Patch foraging water rate 6 sec0.50.81.31.11.0-1.10.90.90.90.90.90.80.90.8-0.8-0.80.80.80.80.80.80.80.71.20.90.0
Seeking ratio, delayed vs. immediate footshock2.02.42.9-1.5-1.61.5-1.7-1.7-1.6-1.6-1.6-1.6-1.7-1.61.61.6-1.6-1.6-1.6-1.6-1.6-1.7-1.4-0.5-1.7-1.3
Distance traveled before self-admin0.20.30.5-0.3-0.50.4-0.6-0.6-0.5-0.5-0.5-0.5-0.6-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.7-0.4-0.7-0.4-0.3
Distance traveled after self-admin0.20.20.5-0.1-0.40.2-0.5-0.5-0.4-0.4-0.4-0.4-0.5-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.6-0.5-0.2-0.3-0.7
Extensor digitorum longus weight0.20.61.1-0.6-0.80.6-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.80.80.8-0.8-0.8-0.8-0.8-0.8-0.7-0.8-1.0-0.8-0.5
Bone: elastic displacement0.00.00.10.20.1-0.30.10.10.20.20.20.20.10.2-0.2-0.20.20.20.20.20.20.20.30.30.20.2
Bone: elastic work0.40.50.80.90.8-0.80.70.70.70.70.70.70.70.7-0.7-0.70.70.70.70.70.70.70.70.90.60.7
Bone: endosteal estimation0.10.10.30.40.4-0.40.30.30.40.40.40.40.30.4-0.4-0.40.40.40.40.40.40.10.5-0.20.30.3
Bone: endosteal perimeter1.22.53.7-1.5-1.51.5-1.7-1.7-1.6-1.6-1.6-1.6-1.7-1.61.61.6-1.6-1.6-1.6-1.6-1.6-1.4-1.5-1.9-1.5-1.0
Epididymis fat weight0.41.21.81.01.0-1.01.21.21.11.11.11.11.21.1-1.1-1.11.11.11.11.11.11.11.21.01.01.3
Delta time in closed arm before/after self-admin0.40.40.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.6-0.6-0.5-0.7-0.8-0.6-0.4
Delta time in open arm before/after self-admin0.40.40.50.70.7-0.70.60.60.60.60.60.60.60.7-0.6-0.60.60.60.60.70.60.30.60.50.70.3
Diff in mean of infusions in LGA sessions0.00.00.2-0.2-0.00.10.10.10.00.00.00.00.10.0-0.0-0.00.00.00.0-0.00.00.2-0.00.20.00.5
Delay discount exponential model param2.02.22.41.51.5-1.51.51.51.51.51.51.51.31.5-1.5-1.51.51.51.51.51.51.41.41.31.41.1
Extinction: sum of active levers before priming0.00.00.0-0.1-0.10.1-0.2-0.2-0.1-0.1-0.1-0.1-0.2-0.20.10.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.2-0.20.2
Active lever presses in extinction session 60.10.10.30.30.3-0.30.20.20.30.30.30.30.20.3-0.3-0.30.30.30.30.30.30.10.4-0.10.20.6
Bone: final force1.01.62.01.31.4-1.31.21.21.31.31.31.31.21.2-1.3-1.31.31.31.31.31.31.31.31.41.21.0
Bone: final moment1.22.02.51.51.5-1.51.41.41.41.41.41.41.41.4-1.4-1.41.41.41.41.41.41.41.41.61.31.1
Food consumed during 24 hour testing period1.41.92.21.51.5-1.51.31.31.41.41.41.41.31.3-1.4-1.41.41.41.41.41.41.41.31.41.30.9
Glucose1.01.51.81.31.3-1.31.31.31.31.31.21.21.31.2-1.2-1.21.21.21.21.21.21.31.11.01.21.2
Heart weight1.72.63.41.61.7-1.61.51.51.61.61.61.61.51.5-1.6-1.61.61.61.61.61.61.61.81.41.51.8
Delay discount hyperbolic model param2.22.52.71.61.6-1.71.61.61.61.61.61.61.41.6-1.6-1.61.61.61.61.61.61.51.51.41.51.2
Intermittent access intake day 1-15 change0.61.31.6-1.2-1.11.2-1.3-1.3-1.1-1.1-1.1-1.1-1.2-1.21.11.1-1.1-1.1-1.1-1.1-1.1-1.2-0.9-1.3-1.2-0.7
Intermittent access intake escalation0.91.82.1-1.4-1.31.4-1.5-1.5-1.3-1.3-1.3-1.3-1.4-1.41.41.4-1.4-1.3-1.4-1.4-1.3-1.4-1.1-1.4-1.4-0.9
Intermittent access intake escalation 20.10.20.3-0.4-0.40.4-0.5-0.5-0.4-0.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.2-0.5-0.4-0.2
Intermitt. access day 1 inactive lever presses0.00.10.2-0.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.3-0.50.2-0.4-0.3
Intermitt. access day 15 inactive lever presses1.02.02.7-1.4-1.41.4-1.4-1.4-1.5-1.5-1.5-1.5-1.4-1.41.51.5-1.5-1.5-1.5-1.5-1.5-1.6-1.6-0.6-1.3-1.3
Intermitt. access escalation Index0.00.00.2-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.4-0.1-0.1
Intermittent access day 1 total infusions0.20.40.7-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.70.60.6-0.6-0.6-0.6-0.6-0.6-0.8-0.4-0.5-0.7-0.5
Intermittent access day 15 total infusions1.52.32.9-1.6-1.51.6-1.6-1.6-1.5-1.5-1.5-1.5-1.6-1.61.51.5-1.5-1.5-1.5-1.5-1.5-1.7-1.2-1.7-1.6-1.0
Intermittent access terminal intake (last 3 days)1.21.62.2-1.3-1.21.3-1.3-1.3-1.3-1.2-1.2-1.2-1.3-1.31.31.3-1.3-1.3-1.3-1.3-1.2-1.4-0.9-1.5-1.3-0.8
Intermittent access total infusions1.82.22.7-1.6-1.41.6-1.6-1.6-1.5-1.5-1.5-1.5-1.6-1.61.51.5-1.5-1.5-1.5-1.5-1.4-1.6-1.1-1.5-1.6-1.0
Intermittent access day 1 locomotion0.10.10.10.30.3-0.30.30.30.30.30.30.30.30.3-0.3-0.30.30.30.30.30.30.00.30.30.20.1
Intermittent access day 15 total locomotion0.30.51.1-0.8-0.60.8-0.8-0.8-0.7-0.6-0.6-0.7-0.8-0.70.70.7-0.7-0.7-0.7-0.7-0.6-0.8-0.5-1.1-0.8-0.3
Intermittent access total locomotion0.91.11.5-1.1-1.01.1-1.1-1.1-1.0-1.0-1.0-1.0-1.1-1.11.01.0-1.1-1.0-1.1-1.1-1.0-1.1-0.8-1.2-1.1-0.7
Intermittent access standard deviation0.00.00.1-0.00.00.0-0.0-0.00.00.00.00.0-0.00.0-0.0-0.00.00.00.00.00.0-0.20.00.4-0.00.0
Left kidney weight0.73.34.01.82.0-1.71.91.91.81.81.81.81.91.8-1.8-1.81.81.81.81.81.82.01.71.71.71.9
Right kidney weight0.31.31.81.11.3-1.11.11.11.21.21.21.21.11.1-1.1-1.11.11.11.11.11.11.31.31.01.11.2
Cocaine induced anxiety0.00.00.30.10.1-0.10.20.20.10.10.10.10.10.1-0.1-0.10.10.10.10.10.10.20.20.50.1-0.0
Post-drug Anxiety0.00.00.1-0.2-0.20.2-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.2-0.2-0.0-0.10.0-0.1-0.2
Baseline Anxiety0.10.10.2-0.2-0.20.2-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.4-0.3-0.4-0.2-0.3
Tail length5.019.521.54.34.4-4.34.64.64.54.54.54.54.64.6-4.5-4.54.54.54.54.54.54.24.34.64.33.1
Length with tail9.239.945.36.46.4-6.46.46.46.46.46.46.46.46.4-6.4-6.46.46.46.46.46.46.16.36.76.04.8
Length without tail7.524.327.05.25.1-5.14.84.85.05.05.05.04.84.9-5.0-5.05.05.05.04.95.04.95.15.14.63.9
Times rat made contact with spout0.40.40.80.60.6-0.60.60.60.70.70.70.70.60.7-0.7-0.70.70.70.70.70.70.90.60.50.70.6
Lifetime Intake2.02.42.9-1.6-1.51.7-1.6-1.6-1.5-1.5-1.5-1.5-1.6-1.61.61.6-1.6-1.5-1.6-1.6-1.5-1.7-1.3-1.6-1.6-1.0
Liver weight, left0.61.02.30.90.9-0.91.11.11.01.01.01.01.11.1-1.0-1.01.01.01.01.01.01.00.91.51.00.6
Liver weight, right1.62.85.21.71.7-1.71.71.71.71.71.71.71.71.7-1.7-1.71.71.71.71.71.71.51.62.31.60.8
Locomotor activity5.99.210.33.23.2-3.22.92.93.23.23.23.22.83.1-3.2-3.23.23.23.23.13.22.83.12.32.92.3
Locomotor testing distance4.88.79.83.13.1-3.13.03.03.13.13.13.12.93.0-3.1-3.13.13.13.13.03.12.43.02.32.82.1
Locomotor testing rearing0.10.20.40.60.4-0.60.40.40.50.50.50.50.30.5-0.5-0.50.50.50.50.50.6-0.10.60.00.30.3
Locomotion in novel chamber0.20.20.4-0.4-0.50.5-0.6-0.6-0.4-0.4-0.4-0.4-0.6-0.50.40.4-0.4-0.4-0.4-0.5-0.4-0.3-0.0-0.2-0.4-0.4
Locomotion in novel chamber post-restriction0.40.70.80.80.8-0.80.80.80.90.90.90.90.80.8-0.9-0.90.90.90.90.90.90.90.90.30.80.8
Fecal boli incidents, locomotor time 10.30.50.70.70.7-0.70.80.80.70.70.70.70.80.6-0.7-0.70.70.70.70.70.70.50.70.70.70.7
Change in fecal boli incidents, locomotor task0.00.00.0-0.0-0.10.0-0.1-0.1-0.0-0.0-0.0-0.10.1-0.00.00.0-0.0-0.0-0.0-0.0-0.0-0.1-0.10.1-0.1-0.2
Time >=10cm from walls, locomotor time 10.20.20.7-0.3-0.40.3-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.30.40.4-0.4-0.4-0.4-0.4-0.4-0.3-0.5-0.1-0.4-0.9
Bouts of movement, locomotor time 10.10.10.80.20.2-0.20.30.30.20.20.20.20.40.2-0.2-0.20.20.20.20.20.20.00.10.90.1-0.1
Total resting periods, locomotor time 10.00.10.70.10.1-0.10.30.30.10.10.20.10.30.1-0.2-0.20.20.20.20.20.2-0.00.10.80.1-0.1
Rest time, locomotor task time 10.40.50.9-0.9-0.90.9-0.4-0.4-0.8-0.8-0.8-0.8-0.3-0.80.80.8-0.8-0.8-0.8-0.8-0.8-0.9-0.6-0.1-0.7-0.6
Distance moved, locomotor task time 11.01.62.11.31.3-1.31.11.11.31.31.31.31.01.3-1.3-1.31.31.31.31.31.31.51.20.91.31.2
Vertical activity count, locomotor time 10.40.91.51.01.0-1.00.90.91.01.01.01.00.71.0-1.0-1.01.01.01.00.91.01.20.80.40.90.9
Time >=10cm from walls, locomotor time 21.01.51.91.21.3-1.21.21.21.31.31.31.31.21.3-1.3-1.31.31.31.31.31.31.21.11.41.21.1
Bouts of movement, locomotor time 20.00.00.20.10.2-0.1-0.2-0.20.10.10.10.10.00.0-0.1-0.10.10.10.10.10.1-0.00.1-0.20.00.5
Total resting periods, locomotor time 20.00.10.2-0.1-0.10.2-0.5-0.5-0.1-0.1-0.1-0.1-0.2-0.20.20.2-0.2-0.2-0.2-0.1-0.1-0.3-0.2-0.5-0.20.3
Rest time, locomotor task time 20.00.00.2-0.1-0.20.2-0.1-0.1-0.2-0.2-0.2-0.2-0.0-0.20.20.2-0.2-0.2-0.2-0.2-0.2-0.4-0.10.0-0.1-0.4
Distance moved, locomotor task time 20.81.01.61.01.0-1.01.01.01.01.01.01.00.91.0-1.0-1.01.01.01.01.01.01.30.90.91.01.0
Vertical activity count, locomotor time 20.00.00.40.10.2-0.20.10.10.20.20.20.2-0.10.2-0.2-0.20.20.20.20.10.20.40.2-0.20.20.6
Light reinforcement 10.41.01.21.01.1-0.91.01.01.01.01.01.01.11.0-1.0-1.01.01.01.01.01.01.10.70.61.10.7
Light reinforcement 20.10.10.5-0.1-0.10.2-0.1-0.1-0.3-0.3-0.3-0.3-0.0-0.30.30.3-0.3-0.3-0.3-0.3-0.4-0.1-0.7-0.5-0.1-0.5
Bone: marrow area0.10.10.30.40.4-0.50.30.30.40.40.40.40.30.4-0.4-0.40.40.40.40.40.40.10.5-0.10.30.3
Bone: maximum diameter0.40.81.0-0.8-0.90.8-1.0-1.0-0.9-0.9-0.9-0.9-1.0-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.5-0.9-0.7
Bone: maximum force0.71.21.51.21.2-1.21.01.01.11.11.11.11.01.1-1.1-1.11.11.11.11.11.11.01.21.21.00.8
Bone: maximum moment0.81.41.71.31.3-1.31.11.11.21.21.21.21.11.2-1.2-1.21.21.21.21.21.21.11.21.31.10.8
Mean time between licks in bursts0.71.82.2-1.1-1.31.1-1.5-1.5-1.4-1.4-1.4-1.4-1.5-1.41.41.4-1.4-1.4-1.4-1.4-1.4-1.5-1.1-1.0-1.4-1.3
Mean num. licks in bursts0.50.81.30.90.9-0.80.90.90.90.90.90.90.90.9-0.9-0.90.90.90.90.90.91.10.70.80.90.5
Cd content in liver0.10.10.2-0.3-0.30.3-0.4-0.4-0.3-0.3-0.3-0.3-0.4-0.40.30.3-0.3-0.3-0.3-0.4-0.3-0.2-0.3-0.5-0.3-0.3
Co content in liver1.21.42.0-1.2-1.31.1-1.3-1.3-1.2-1.2-1.2-1.2-1.3-1.21.21.2-1.2-1.2-1.2-1.2-1.2-1.4-1.1-0.8-1.1-1.2
Cu content in liver4.14.95.32.32.3-2.32.22.22.32.22.22.22.22.2-2.2-2.22.22.22.22.22.22.12.22.02.11.9
Fe content in liver1.11.31.71.00.9-1.11.01.01.21.21.21.21.01.2-1.2-1.21.21.21.21.21.21.01.31.21.10.9
K content in liver0.20.20.40.60.6-0.50.50.50.40.40.40.40.50.4-0.4-0.40.40.40.40.40.40.60.20.20.50.5
Mg content in liver0.80.81.2-0.5-0.50.6-0.8-0.8-0.9-0.9-0.9-1.0-0.8-1.01.01.0-1.0-1.0-1.0-1.0-1.0-0.8-1.1-1.0-0.8-0.7
Mn content in liver0.10.10.20.50.5-0.40.30.30.20.20.10.10.30.1-0.1-0.10.10.10.10.10.10.3-0.1-0.00.2-0.0
Na content in liver0.40.50.60.40.5-0.60.60.60.70.70.70.70.60.8-0.7-0.70.70.70.70.70.70.60.70.80.60.5
Rb content in liver0.60.72.60.80.4-0.90.50.50.80.80.90.90.50.9-0.9-0.90.90.90.90.90.90.21.11.60.6-0.1
Se content in liver0.10.10.40.10.3-0.00.40.40.20.20.20.20.40.2-0.1-0.10.10.10.10.20.10.4-0.10.00.30.6
Sr content in liver0.10.10.20.30.4-0.00.30.3-0.0-0.1-0.1-0.10.3-0.20.20.2-0.2-0.2-0.2-0.2-0.20.3-0.4-0.40.10.3
Zn content in liver2.12.42.91.71.7-1.61.51.51.61.61.61.61.51.5-1.5-1.51.51.51.51.51.51.61.51.61.41.2
Bone: minimum diameter0.50.81.2-0.8-0.80.8-1.0-1.0-0.9-0.9-0.9-0.9-1.0-1.00.90.9-0.9-0.9-0.9-0.9-0.9-1.1-0.8-0.4-1.0-0.9
Time in familiar zone, hab. session 11.31.32.3-1.2-1.31.1-1.3-1.3-1.1-1.1-1.1-1.1-1.3-1.11.11.1-1.1-1.1-1.1-1.1-1.1-1.5-0.8-0.7-1.1-1.0
Time in novel zone, hab. session 10.60.61.10.80.9-0.70.90.90.80.80.80.80.90.8-0.7-0.70.70.70.70.70.71.10.50.60.80.6
Total zone transitions, hab. session 10.60.91.51.11.2-1.01.11.10.90.90.90.91.10.8-0.9-0.90.90.90.90.90.91.20.70.21.01.0
Total locomotion distance, hab. session 10.30.40.60.70.7-0.60.80.80.60.60.60.60.80.6-0.6-0.60.60.60.60.60.60.80.40.40.70.6
Locomotion velocity, hab. session 10.30.40.80.70.8-0.60.80.80.60.60.60.60.80.6-0.6-0.60.60.60.60.60.60.90.50.30.70.7
Time in familiar zone, hab. session 20.50.61.1-0.7-0.80.6-0.9-0.9-0.7-0.7-0.7-0.7-0.9-0.80.70.7-0.7-0.7-0.7-0.7-0.7-1.0-0.50.0-0.9-0.7
Time in novel zone, hab. session 20.00.00.20.20.1-0.20.10.10.20.20.20.20.10.2-0.2-0.20.20.20.20.20.20.20.2-0.50.20.1
Total zone transitions, hab. session 20.10.20.50.60.6-0.50.40.40.30.30.30.30.40.2-0.2-0.20.20.20.20.20.20.60.1-0.50.30.7
Total locomotion distance, hab. session 20.30.40.90.70.8-0.60.80.80.60.60.60.60.80.6-0.6-0.60.60.60.60.60.60.90.40.20.70.9
Locomotion velocity, hab. session 20.20.30.80.60.7-0.50.70.70.50.50.50.50.70.5-0.5-0.50.50.50.50.50.40.90.20.00.60.9
Novel to familiar place preference ratio0.80.91.11.11.0-1.10.90.91.01.01.01.00.90.9-1.0-1.01.01.01.01.01.00.71.00.50.80.5
Novelty place preference0.80.81.11.00.9-1.00.90.90.90.90.90.90.90.9-0.9-0.90.90.90.90.91.00.71.00.50.80.4
Time in novel zone, NPP test1.01.11.41.21.0-1.21.01.01.11.11.11.11.01.1-1.1-1.11.11.11.11.11.10.81.10.71.00.5
Total zone transitions, NPP test2.53.65.42.22.3-2.02.12.11.91.91.81.82.11.7-1.8-1.81.81.81.81.81.82.31.61.21.81.8
Total locomotion distance, NPP test1.11.52.41.31.4-1.21.41.41.21.21.21.21.41.1-1.1-1.11.11.11.11.11.11.50.90.91.21.3
Locomotion velocity, NPP test1.11.62.71.41.5-1.31.41.41.31.21.21.21.41.2-1.2-1.21.21.21.21.21.21.71.00.81.31.4
Intraocular pressure0.91.21.60.90.9-1.01.01.01.21.21.21.21.01.3-1.2-1.21.21.21.21.21.20.91.20.51.11.0
Delta distance traveled before/after self-admin0.00.00.20.30.2-0.30.20.20.20.20.20.20.20.2-0.2-0.20.20.20.20.20.20.1-0.00.40.2-0.2
Delta ambulatory time before/after self-admin0.91.11.51.21.1-1.21.11.11.11.11.11.11.11.1-1.1-1.11.11.11.11.11.10.80.81.21.00.4
Parametrial fat weight0.81.82.71.41.5-1.31.41.41.41.31.31.31.41.4-1.3-1.31.31.31.31.31.31.61.01.11.41.1
Pavlov. Cond. lever latency4.15.15.72.32.2-2.32.22.22.32.32.32.42.22.4-2.4-2.42.42.42.42.42.42.22.42.12.21.6
Pavlov. Cond. magazine entry latency7.49.510.3-3.1-3.13.1-3.2-3.2-3.1-3.1-3.1-3.2-3.2-3.23.23.2-3.2-3.2-3.2-3.2-3.1-3.0-3.1-2.8-3.1-2.2
Pavlov. Cond. change in total contacts1.61.72.1-1.4-1.41.3-1.5-1.5-1.3-1.3-1.3-1.3-1.5-1.31.31.3-1.3-1.3-1.3-1.3-1.3-1.4-1.1-0.8-1.3-1.2
Pavlov. Cond. index score6.37.98.5-2.8-2.82.8-2.9-2.9-2.9-2.9-2.9-2.9-2.9-2.92.92.9-2.9-2.9-2.9-2.9-2.9-2.7-2.8-2.6-2.8-2.0
Pavlov. Cond. latency score6.07.68.2-2.7-2.72.7-2.8-2.8-2.8-2.8-2.8-2.8-2.8-2.92.82.8-2.8-2.8-2.8-2.9-2.8-2.7-2.8-2.6-2.7-2.0
Pavlov. Cond. lever contacts2.42.93.3-1.7-1.61.7-1.7-1.7-1.8-1.8-1.8-1.8-1.7-1.81.81.8-1.8-1.8-1.8-1.8-1.8-1.5-1.8-1.5-1.7-1.1
Pavlov. Cond. magazine entry number7.79.710.73.13.1-3.13.33.33.23.23.23.23.33.2-3.2-3.23.23.23.23.23.13.03.02.93.12.3
Pavlov. Cond. intertrial magazine entries0.50.60.70.60.7-0.70.80.80.70.80.80.80.80.8-0.8-0.80.80.80.80.80.80.50.80.60.70.7
Pavlov. Cond. lever-magazine prob. diff.5.66.97.5-2.6-2.62.6-2.7-2.7-2.7-2.7-2.7-2.7-2.7-2.72.72.7-2.7-2.7-2.7-2.7-2.7-2.5-2.6-2.4-2.6-1.9
Pavlov. Cond. response bias6.78.39.0-2.8-2.92.9-3.0-3.0-2.9-2.9-2.9-3.0-3.0-3.03.03.0-3.0-3.0-3.0-3.0-3.0-2.7-2.9-2.7-2.8-2.0
Pavlov. Cond. lever latency0.81.01.5-1.2-1.21.2-1.0-1.0-1.0-1.0-1.0-1.0-1.1-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.6-1.0-0.9
Pavlov. Cond. magazine entry latency0.10.10.60.0-0.10.1-0.2-0.2-0.3-0.3-0.3-0.3-0.2-0.40.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.7-0.2-0.0
Pavlov. Cond. change in total contacts2.43.95.12.32.2-2.21.91.92.02.02.02.02.01.9-2.0-2.02.02.02.02.02.01.82.01.91.91.4
Pavlov. Cond. index score0.30.40.70.90.8-0.80.60.60.60.60.60.60.60.5-0.5-0.50.50.50.50.50.60.50.60.20.60.6
Pavlov. Cond. latency score0.20.20.50.70.7-0.60.50.50.40.40.40.40.50.3-0.4-0.40.40.40.40.40.40.40.40.10.40.5
Pavlov. Cond. lever contacts1.01.42.01.41.4-1.31.21.21.21.21.21.21.31.2-1.2-1.21.21.21.21.21.21.21.20.81.21.0
Pavlov. Cond. magazine entry number0.10.20.70.10.2-0.20.40.40.40.40.40.40.40.5-0.4-0.40.40.40.40.40.40.40.20.80.40.2
Pavlov. Cond. intertrial magazine entries0.60.91.4-1.1-1.21.0-1.1-1.1-0.9-0.9-0.9-0.9-1.1-0.90.90.9-0.9-0.9-0.9-0.9-0.9-1.1-0.8-0.5-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.80.8-0.70.60.60.50.50.50.50.60.4-0.5-0.50.50.50.50.50.50.50.50.10.50.5
Pavlov. Cond. response bias0.10.20.40.70.6-0.60.40.40.40.40.40.40.50.3-0.4-0.40.40.40.40.40.40.40.5-0.10.40.5
Time in closed arm before self-admin0.81.02.31.01.0-1.00.90.91.11.11.11.10.91.0-1.1-1.11.11.11.11.11.10.81.50.80.90.8
Time in closed arm after self-admin0.20.20.3-0.5-0.50.5-0.5-0.5-0.4-0.4-0.4-0.4-0.5-0.50.40.4-0.4-0.4-0.4-0.4-0.4-0.3-0.1-0.5-0.5-0.3
Time in open arm before self-admin1.01.11.9-1.3-1.11.2-0.9-0.9-1.1-1.1-1.1-1.1-0.9-1.11.11.1-1.1-1.1-1.1-1.1-1.1-0.6-1.4-0.5-1.1-0.5
Time in open arm after self-admin0.20.20.2-0.5-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.5-0.4-0.4
Bone: periosteal estimation0.00.00.10.20.1-0.2-0.0-0.00.10.10.10.1-0.00.1-0.1-0.10.10.10.10.10.1-0.10.30.20.0-0.0
Bone: periosteal perimeter1.01.72.1-1.3-1.31.3-1.4-1.4-1.3-1.3-1.3-1.3-1.5-1.41.31.3-1.3-1.3-1.3-1.3-1.3-1.3-1.2-1.2-1.3-1.0
Bone: post-yield work0.00.00.40.20.2-0.10.10.10.10.10.10.10.00.1-0.1-0.10.10.10.10.10.10.20.1-0.70.10.3
Progressive ratio test 1 active lever presses0.00.00.2-0.1-0.00.1-0.1-0.1-0.0-0.0-0.0-0.0-0.1-0.10.00.0-0.0-0.0-0.0-0.0-0.0-0.20.3-0.4-0.20.0
Progressive ratio test 1 breakpoint0.00.00.2-0.1-0.00.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.1-0.0-0.20.2-0.4-0.20.0
Progressive ratio test 1 inactive lever presses0.30.50.7-0.7-0.70.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.80.70.7-0.7-0.7-0.7-0.7-0.7-0.8-0.4-0.4-0.7-0.5
Progressive ratio test 2 active lever presses2.32.73.2-1.8-1.61.8-1.8-1.8-1.6-1.6-1.6-1.6-1.8-1.71.71.7-1.7-1.6-1.7-1.7-1.6-1.6-1.4-1.3-1.7-1.0
Progressive ratio test 2 breakpoint2.42.73.2-1.8-1.61.8-1.8-1.8-1.6-1.7-1.7-1.7-1.8-1.71.71.7-1.7-1.7-1.7-1.7-1.6-1.6-1.5-1.3-1.7-1.0
Progressive ratio test 2 inactive lever presses2.33.74.3-2.1-1.92.1-2.0-2.0-2.0-1.9-2.0-2.0-2.1-2.12.02.0-2.0-2.0-2.0-2.0-1.9-2.0-1.5-1.5-2.0-1.3
Incentive Sensitization - Responses2.13.03.4-1.8-1.71.8-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.81.81.8-1.8-1.8-1.8-1.8-1.8-1.7-1.8-1.1-1.7-1.1
Incentive Sensitization - Breakpoint2.33.13.4-1.8-1.71.9-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.81.81.8-1.8-1.8-1.8-1.8-1.8-1.7-1.8-1.1-1.7-1.1
Sum of active levers in priming session hrs 5-60.00.00.2-0.1-0.10.00.10.1-0.0-0.0-0.0-0.00.1-0.00.00.0-0.0-0.0-0.0-0.0-0.00.2-0.1-0.3-0.10.5
Progressive ratio2.23.44.32.01.8-1.91.71.71.91.91.91.91.81.8-1.9-1.91.91.91.91.91.91.92.12.01.71.0
Food seeking constrained by brief footshock1.21.42.1-1.2-1.21.2-1.4-1.4-1.2-1.2-1.2-1.2-1.4-1.21.21.2-1.2-1.2-1.2-1.2-1.2-1.0-1.1-0.6-1.2-1.0
Seeking ratio, punishment vs. effort4.36.27.0-2.6-2.52.5-2.6-2.6-2.5-2.5-2.6-2.6-2.6-2.52.62.6-2.6-2.6-2.6-2.6-2.6-2.4-2.6-2.1-2.4-1.7
Retroperitoneal fat weight1.66.97.82.62.7-2.62.72.72.72.72.62.62.72.7-2.6-2.62.62.62.62.62.62.82.42.42.72.3
Reaction time number correct0.30.50.9-0.6-0.80.6-0.9-0.9-0.7-0.7-0.7-0.7-0.8-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.8-0.5-0.3-0.7-0.8
Reaction time mean minus median0.00.10.20.30.5-0.20.30.30.30.30.30.30.20.3-0.3-0.30.30.30.30.30.30.5-0.10.40.30.1
Reaction time mean minus median AUC0.10.30.50.60.7-0.50.60.60.60.60.60.60.50.6-0.6-0.60.60.60.60.60.60.50.30.70.5-0.0
Reaction time num false alarms0.20.30.7-0.6-0.70.5-0.7-0.7-0.6-0.5-0.5-0.5-0.7-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.8-0.3-0.7-0.6-0.6
Reaction time num false alarms AUC0.10.10.2-0.4-0.40.3-0.4-0.4-0.3-0.3-0.3-0.3-0.4-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.5-0.1-0.4-0.4-0.4
Reaction time trials correct on left0.30.50.9-0.6-0.80.6-0.9-0.9-0.7-0.7-0.7-0.7-0.8-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.8-0.5-0.3-0.7-0.8
Reaction time trials on left0.30.61.0-0.6-0.80.7-1.0-1.0-0.7-0.7-0.7-0.7-0.9-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.8-0.5-0.3-0.8-0.8
Reaction time mean0.00.00.1-0.00.10.00.20.20.10.10.10.10.10.1-0.1-0.10.10.10.10.10.10.10.1-0.20.10.3
Reaction time mean AUC0.00.00.0-0.10.00.10.10.10.00.00.00.0-0.00.1-0.0-0.00.00.00.00.00.1-0.00.0-0.2-0.00.1
Median of all reaction times0.00.00.2-0.2-0.10.20.00.0-0.0-0.0-0.0-0.0-0.1-0.00.00.0-0.0-0.0-0.0-0.0-0.0-0.20.1-0.4-0.10.2
Reaction time omissions0.10.20.5-0.7-0.60.6-0.6-0.6-0.4-0.4-0.4-0.4-0.6-0.30.40.4-0.4-0.4-0.4-0.4-0.4-0.3-0.5-0.5-0.5-0.2
Reaction time false alarm rate0.00.00.1-0.2-0.20.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.10.10.1-0.1-0.1-0.1-0.1-0.1-0.30.0-0.4-0.1-0.2
Reaction time premature initiation rate2.12.93.41.71.8-1.71.71.71.71.71.71.71.71.9-1.7-1.71.71.71.71.81.71.81.21.51.71.3
Reaction time premature initiations0.81.41.71.31.2-1.21.11.11.21.21.21.21.11.3-1.2-1.21.21.21.21.21.21.30.81.21.20.8
Std. dev. reaction times0.10.20.20.30.5-0.30.40.40.40.40.40.40.30.4-0.4-0.40.40.40.40.40.40.50.30.20.30.2
Reaction time trials completed0.30.61.0-0.6-0.80.7-1.0-1.0-0.7-0.7-0.7-0.7-0.9-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.8-0.5-0.3-0.8-0.8
Reaction time trials AUC0.40.71.2-0.7-0.90.8-1.1-1.1-0.8-0.8-0.8-0.8-1.0-0.90.80.8-0.8-0.8-0.8-0.8-0.8-0.9-0.6-0.4-0.9-0.8
Run reversals in cocaine runway, females1.11.11.5-1.2-1.11.2-1.0-1.0-1.1-1.1-1.1-1.1-1.0-1.01.11.1-1.1-1.1-1.1-1.1-1.1-0.8-1.2-0.9-0.9-0.9
Run reversals in cocaine runway, males0.90.91.51.11.0-1.00.90.90.90.90.90.90.91.0-0.9-0.90.90.90.90.90.91.00.71.21.00.6
Latency to leave start box in cocaine runway0.20.30.60.70.5-0.70.40.40.50.50.50.50.40.5-0.5-0.50.50.50.50.50.50.60.40.70.50.2
Latency to leave start box in cocaine runway, F0.80.91.31.11.0-1.20.80.81.01.01.00.90.81.0-0.9-0.90.91.00.90.90.91.00.90.70.90.6
Latency to leave start box in cocaine runway, M0.90.81.3-1.1-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.7-1.1-0.1-0.8-0.5
Std. dev. time between licks in bursts3.64.96.6-2.0-2.22.0-2.4-2.4-2.2-2.2-2.2-2.2-2.4-2.32.22.2-2.2-2.2-2.2-2.2-2.2-2.6-1.9-2.0-2.2-1.8
Total sessions with >9 infusions0.60.70.8-0.9-0.80.9-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.80.80.8-0.8-0.8-0.8-0.9-0.8-0.9-0.9-0.5-0.9-0.4
Short access day 1 total inactive lever presses3.24.35.4-2.2-2.02.2-2.2-2.2-2.1-2.1-2.1-2.1-2.2-2.22.12.1-2.1-2.1-2.1-2.1-2.1-2.3-1.8-2.0-2.1-1.3
Short access day 10 total inactive lever presses0.10.21.80.30.3-0.30.30.30.30.30.30.30.30.3-0.3-0.30.30.30.30.30.30.20.11.30.3-0.0
Short access day 1 total infusions2.93.84.3-2.0-1.92.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.02.02.0-2.0-2.0-2.0-2.0-2.0-2.1-2.0-1.5-1.9-1.5
Short access day 10 total infusions2.22.83.1-1.7-1.61.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.71.71.7-1.7-1.7-1.7-1.7-1.7-1.8-1.5-1.5-1.7-1.2
Short access total infusions3.24.04.4-2.1-2.02.1-2.1-2.1-2.0-2.0-2.0-2.0-2.1-2.12.02.0-2.0-2.0-2.0-2.0-2.0-2.1-1.9-2.0-2.0-1.3
Short access day 1 locomotion0.60.81.0-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.8-1.0-0.7-0.8-0.4
Short access day 10 total locomotion0.00.00.10.10.2-0.10.10.10.20.20.20.20.10.1-0.2-0.20.20.20.20.20.20.10.20.30.10.0
Short access total locomotion0.10.10.2-0.3-0.20.3-0.3-0.3-0.2-0.2-0.2-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.2-0.2-0.3-0.4-0.30.0
One hour access (0.3 mA shock)0.60.60.9-0.9-0.80.9-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.90.80.8-0.8-0.8-0.8-0.8-0.8-1.0-0.4-0.6-1.0-0.6
Compulsive drug intake0.60.71.0-0.7-0.90.7-0.8-0.8-0.9-0.9-0.9-0.9-0.7-0.80.90.9-0.9-0.9-0.9-0.8-0.9-0.8-0.9-0.5-0.8-1.0
One hour access (shock baseline)0.30.50.7-0.9-0.70.9-0.8-0.8-0.7-0.7-0.7-0.7-0.9-0.80.70.7-0.7-0.7-0.7-0.7-0.7-0.8-0.3-0.8-0.8-0.2
Social response proportion0.20.20.50.40.4-0.30.30.30.50.50.50.50.30.5-0.5-0.50.50.50.50.50.50.70.30.50.50.3
Social responses0.30.40.60.70.7-0.50.60.60.60.60.60.60.50.6-0.6-0.60.60.60.60.60.60.80.50.30.70.3
Social time0.40.51.1-0.7-0.70.8-0.5-0.5-0.8-0.8-0.8-0.8-0.6-0.70.80.8-0.8-0.8-0.8-0.8-0.8-0.6-1.0-0.5-0.6-0.6
Soleus weight4.212.414.33.83.7-3.83.63.63.63.63.63.63.73.5-3.6-3.63.63.63.63.53.63.43.53.13.42.7
Bone: stiffness0.20.20.80.50.5-0.50.40.40.50.50.50.50.40.5-0.5-0.50.50.50.50.50.50.40.50.90.40.2
Tibialis anterior weight0.00.00.30.30.2-0.30.10.10.20.20.20.20.20.1-0.2-0.20.20.20.20.20.20.30.2-0.30.20.5
Time to tail flick, vehicle, before self-admin1.91.93.21.41.3-1.41.51.51.41.41.41.41.51.4-1.4-1.41.41.41.41.41.41.21.41.81.30.8
Time to tail flick, vehicle, after self-admin0.10.20.40.60.4-0.60.40.40.40.40.40.40.40.4-0.4-0.40.40.40.40.40.40.30.50.10.40.4
Time to tail flick, test, before self-admin0.00.00.3-0.1-0.10.10.10.1-0.1-0.1-0.1-0.10.1-0.00.10.1-0.1-0.1-0.1-0.1-0.20.1-0.5-0.5-0.00.0
Time to tail flick, test, after self-admin0.20.20.3-0.6-0.40.6-0.3-0.3-0.4-0.4-0.4-0.4-0.3-0.50.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.2-0.5-0.1
Delta time to tail flick, vehicle, before/after SA0.50.50.9-0.6-0.60.6-0.8-0.8-0.7-0.7-0.7-0.7-0.8-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-1.0-0.6-0.5
Delta time to tail flick, test, before/after SA0.20.20.3-0.5-0.40.5-0.5-0.5-0.4-0.4-0.4-0.4-0.5-0.50.40.4-0.4-0.4-0.4-0.4-0.4-0.60.1-0.2-0.5-0.2
Tibia length6.818.922.84.64.8-4.54.54.54.44.44.44.34.54.2-4.3-4.34.34.34.34.34.34.54.24.24.13.5
Ambulatory time before self-admin0.60.81.3-0.8-0.90.8-1.0-1.0-0.9-0.9-0.9-0.9-1.0-1.00.90.9-0.9-0.9-0.9-0.9-0.9-1.1-0.7-1.2-0.8-0.6
Ambulatory time after self-admin0.00.00.20.2-0.1-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.1-0.1-0.4-0.2-0.3-0.0-0.3
Bone: tissue strength3.43.44.41.91.9-1.91.91.91.91.91.91.91.81.8-1.9-1.91.91.91.91.91.91.61.92.11.81.3
Total heroin consumption2.02.42.91.51.6-1.61.61.61.51.51.51.51.61.6-1.5-1.51.51.51.51.51.51.31.51.31.51.7
Bone: trabecular number0.61.02.2-1.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.0-1.0-0.9-1.0-1.5-1.0-0.8
Bone: trabecular spacing1.62.14.61.41.4-1.41.51.51.41.41.41.41.51.5-1.4-1.41.41.41.41.51.41.31.32.11.41.0
Bone: trabecular thickness0.00.10.20.20.3-0.20.30.30.20.20.20.20.30.2-0.2-0.20.20.20.20.20.20.40.0-0.30.20.3
Bone: trabecular tissue density0.40.60.80.80.9-0.70.90.90.80.70.70.70.80.7-0.7-0.70.70.70.70.70.70.80.60.90.80.6
Water consumed over 24 hours0.00.00.20.10.2-0.10.10.10.20.10.10.10.10.1-0.1-0.10.10.10.10.10.10.3-0.00.50.20.2
Number of responses in last shaping day0.20.30.6-0.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.60.50.5-0.5-0.5-0.5-0.5-0.5-0.8-0.3-0.1-0.5-0.4