Hub : Genes

Setd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Setd2 0.19 0.1 0.0e+00 0.24 0.24 0.24 0.24 1.0e-26 1.0e-26 2.0e-26 7.2e-27
2 BLA gene expression Setd2 0.13 0.12 6.4e-06 0.06 0.09 0.08 0.08 3.1e-04 1.6e-05 5.9e-05 6.2e-05
3 PL mRNA stability Setd2 0.08 0.07 2.3e-08 0.06 0.07 0.06 0.07 1.6e-07 4.0e-08 4.2e-07 6.5e-08
4 Liver intron excision ratio chr8_110577589_110580631 0.06 0.04 4.1e-07 0.05 0.06 0.03 0.05 7.2e-06 6.9e-07 1.4e-04 3.8e-06
5 Eye gene expression Setd2 0.31 0.23 4.4e-03 0.02 0.06 -0.02 0.01 1.7e-01 4.8e-02 9.2e-01 2.4e-01
6 Brain mRNA stability Setd2 0.26 0.14 0.0e+00 0.28 0.33 0.3 0.3 3.1e-26 5.1e-31 9.5e-29 1.1e-28
7 Brain alternative TSS XM_039081608.1 0.06 0.05 1.5e-05 0.05 0.05 0.05 0.05 2.3e-05 9.8e-06 3.1e-05 2.5e-05
8 Brain alternative TSS NM_001401163.1 0.06 0.06 3.4e-05 0.04 0.05 0.05 0.05 9.0e-05 1.5e-05 1.9e-05 2.5e-05
9 NAcc alternative TSS NM_001401163.1 0.04 0.04 1.7e-04 0.03 0.03 0.02 0.03 1.7e-04 5.2e-04 8.7e-04 3.2e-04
10 Liver isoform ratio XM_039081611.1 0.11 0.09 6.6e-11 0.08 0.09 0.09 0.09 2.2e-09 3.1e-10 8.6e-10 3.8e-10
11 Liver mRNA stability Setd2 0.04 0.04 1.1e-03 0.03 0.03 0.03 0.03 5.4e-04 4.3e-04 5.9e-04 5.8e-04
12 NAcc mRNA stability Setd2 0.12 0.12 8.7e-10 0.08 0.08 0.08 0.08 6.2e-10 1.9e-09 1.3e-09 1.7e-09
13 PL gene expression Setd2 0.04 0.04 6.0e-04 0.03 0.03 0.02 0.03 5.7e-04 8.5e-04 2.9e-03 7.3e-04
14 NAcc gene expression Setd2 0.08 0.07 3.6e-09 0.09 0.07 0.08 0.09 2.3e-10 5.3e-09 1.7e-09 2.8e-10
15 Brain gene expression Setd2 0.03 0.03 3.2e-03 0.02 0.02 0.01 0.01 9.8e-03 1.0e-02 3.6e-02 2.5e-02
16 Adipose intron excision ratio chr8_110582440_110594351 0.12 0.1 9.6e-03 0 0 0 0 7.5e-02 9.7e-02 2.6e-01 1.5e-01
17 RMTg mRNA stability Setd2 0.16 0.14 3.3e-03 0.07 0.06 0.04 0.08 5.1e-03 8.2e-03 3.1e-02 3.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.00.00.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.20.20.2-0.20.20.20.20.1-0.40.0
Area under the delay curve2.22.33.11.51.61.61.51.51.6-1.51.5-1.5-1.61.5-1.8-1.7-1.4-1.3-1.70.0
BMI with tail0.31.02.4-1.4-1.1-1.0-1.0-1.0-1.10.9-0.90.80.8-0.70.80.90.71.01.50.0
BMI without tail1.53.03.8-1.9-1.9-1.9-1.9-1.9-1.91.9-1.81.81.7-1.71.71.81.81.41.60.0
Body weight6.125.428.9-5.4-5.4-5.4-5.3-5.3-5.45.3-5.25.25.2-5.15.15.15.04.65.10.0
Weight adjusted by age0.20.20.4-0.2-0.5-0.5-0.5-0.5-0.50.5-0.50.50.5-0.50.60.60.5-0.1-0.00.0
Bone surface0.10.10.40.40.30.30.30.30.3-0.30.3-0.3-0.30.4-0.3-0.3-0.3-0.6-0.60.0
Bone volume0.00.00.30.20.10.10.10.10.1-0.10.1-0.2-0.20.2-0.1-0.1-0.1-0.4-0.50.0
Breakpoint value in progressive ratio session0.10.10.5-0.5-0.3-0.3-0.3-0.3-0.30.3-0.30.30.3-0.30.30.10.30.70.60.0
Number of licking bursts0.10.10.20.30.40.40.50.50.4-0.40.4-0.4-0.40.4-0.3-0.3-0.4-0.20.20.0
Context. condit. distance diff. score0.00.00.00.1-0.0-0.0-0.0-0.0-0.00.0-0.00.00.0-0.00.0-0.00.0-0.20.00.0
Locomotion velocity, session 10.10.10.10.20.30.30.30.30.2-0.30.3-0.3-0.30.3-0.2-0.2-0.3-0.3-0.40.0
Locomotion distance, session 10.60.81.4-1.2-1.0-1.0-1.0-1.0-1.00.9-0.90.80.9-0.81.00.90.80.90.70.0
Locomotion velocity, session 20.30.30.50.50.60.60.60.60.5-0.60.6-0.7-0.60.7-0.6-0.6-0.7-0.7-0.40.0
Locomotion distance, session 20.00.10.30.00.10.10.20.20.1-0.20.2-0.3-0.20.3-0.1-0.1-0.3-0.4-0.60.0
Locomotion velocity, session 30.10.10.4-0.2-0.3-0.3-0.3-0.3-0.30.2-0.20.20.1-0.10.20.20.2-0.1-0.60.0
Locomotion distance, session 31.11.22.41.11.01.11.11.11.0-1.11.1-1.2-1.21.2-1.1-1.0-1.2-1.3-1.60.0
Stereotopy head waving bouts, day 30.10.10.9-0.2-0.2-0.2-0.2-0.2-0.20.2-0.20.20.2-0.20.30.30.20.21.00.0
Stereotopy head waving duration, day 30.30.40.6-0.5-0.6-0.6-0.6-0.6-0.60.6-0.60.60.7-0.70.70.70.60.50.80.0
Locomotion velocity, session 70.20.30.4-0.4-0.5-0.5-0.5-0.5-0.50.5-0.50.60.5-0.50.60.60.60.1-0.50.0
Locomotion distance, session 70.70.92.81.00.90.90.90.90.9-0.90.9-0.9-0.90.9-0.8-0.7-0.9-1.2-1.70.0
Stereotopy head waving bouts, day 70.10.10.20.30.20.20.20.20.3-0.20.2-0.2-0.30.2-0.4-0.4-0.2-0.2-0.20.0
Stereotopy head waving duration, day 70.20.20.3-0.5-0.5-0.5-0.5-0.5-0.50.5-0.50.50.5-0.50.40.40.50.60.50.0
Locomotion velocity, session 80.10.10.3-0.6-0.5-0.5-0.4-0.4-0.50.4-0.40.30.3-0.30.40.40.30.30.00.0
Locomotion distance, session 80.10.20.3-0.5-0.5-0.5-0.5-0.5-0.50.4-0.40.30.3-0.30.40.40.30.0-0.40.0
Degree of sensitization distance1.31.31.6-1.2-1.2-1.2-1.2-1.2-1.21.2-1.21.21.3-1.31.21.21.21.21.00.0
Degree of sensitization stereotypy0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.00.1-0.10.20.0-0.1-0.2-0.20.20.2-0.10.0
Conditioned locomotion2.83.34.12.01.91.91.91.91.9-1.91.8-1.8-1.91.8-1.9-1.9-1.8-1.9-2.00.0
Cocaine response after cond. corrected0.30.31.7-0.5-0.5-0.5-0.5-0.5-0.50.5-0.50.50.5-0.50.50.50.50.61.30.0
Cocaine response after cond. not corrected1.71.93.7-1.4-1.4-1.4-1.4-1.4-1.41.4-1.41.41.4-1.41.41.41.31.41.90.0
Cocaine response before conditioning0.91.11.5-1.2-1.2-1.2-1.2-1.2-1.21.1-1.11.11.1-1.01.11.11.00.90.50.0
Saline control response1.31.72.1-1.3-1.4-1.4-1.4-1.4-1.41.4-1.41.41.4-1.41.41.41.41.30.70.0
Bone: connectivity density0.20.31.60.60.50.50.50.50.5-0.50.5-0.5-0.50.5-0.5-0.5-0.4-0.5-1.30.0
Bone: cortical apparent density0.20.30.60.70.60.60.50.50.6-0.50.5-0.4-0.60.5-0.6-0.6-0.6-0.6-0.80.0
Bone: cortical area0.10.20.70.60.40.40.40.40.4-0.40.4-0.4-0.40.4-0.3-0.4-0.4-0.90.10.0
Bone: cortical porosity0.00.00.50.10.20.20.10.10.2-0.10.1-0.1-0.10.0-0.1-0.10.00.1-0.70.0
Bone: cortical porosity0.10.21.00.40.40.40.40.40.4-0.30.3-0.3-0.30.3-0.3-0.3-0.2-0.2-1.00.0
Bone: cortical thickness0.10.21.2-0.2-0.4-0.4-0.4-0.4-0.40.4-0.40.40.4-0.40.40.40.4-0.01.10.0
Bone: cortical thickness0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.10.1-0.10.10.1-0.10.10.10.10.00.10.0
Bone: cortical tissue density0.30.30.60.70.60.60.60.50.6-0.50.5-0.5-0.60.5-0.7-0.6-0.6-0.6-0.80.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.2-0.3-0.3-0.3-0.3-0.30.4-0.40.40.4-0.40.40.40.40.20.40.0
Condit. Reinf. active-inactive response ratio0.30.30.6-0.4-0.5-0.5-0.5-0.5-0.50.6-0.60.60.6-0.60.60.60.60.50.80.0
Condit. Reinf. active responses0.00.00.10.30.10.10.10.10.2-0.10.1-0.0-0.10.0-0.2-0.2-0.0-0.30.00.0
Condit. Reinf. inactive responses0.60.81.11.00.90.90.80.80.9-0.90.8-0.8-0.90.9-1.0-1.1-0.8-1.0-0.80.0
Incentive salience index mean0.10.10.10.30.20.20.20.30.2-0.20.2-0.3-0.20.2-0.2-0.2-0.3-0.4-0.20.0
Condit. Reinf. lever presses1.52.02.41.41.51.51.51.51.4-1.51.5-1.6-1.51.5-1.4-1.4-1.6-1.5-1.30.0
Condit. Reinf. active minus inactive responses2.02.53.2-1.8-1.6-1.6-1.6-1.6-1.71.6-1.61.61.6-1.51.61.61.41.71.70.0
Condit. Reinf. active-inactive response ratio1.61.72.6-1.5-1.3-1.3-1.3-1.3-1.31.3-1.31.31.3-1.21.21.21.21.41.60.0
Condit. Reinf. active responses1.72.32.8-1.7-1.6-1.6-1.6-1.6-1.61.6-1.61.61.6-1.51.61.61.41.61.60.0
Condit. Reinf. inactive responses0.00.00.10.20.10.10.10.10.1-0.10.1-0.1-0.10.10.00.0-0.2-0.2-0.20.0
Condit. Reinf. lever presses2.33.14.0-2.0-1.9-1.8-1.8-1.8-1.91.8-1.81.81.8-1.71.81.81.71.81.90.0
Condit. Reinf. lever reinforcers received1.92.73.2-1.8-1.7-1.7-1.7-1.7-1.71.7-1.71.61.7-1.61.71.71.51.61.70.0
Conditioned reinforcement - actives0.30.30.60.30.60.60.60.60.5-0.60.6-0.7-0.50.6-0.3-0.4-0.7-0.2-0.40.0
Conditioned reinforcement - inactives0.80.91.41.11.01.01.01.01.0-1.01.0-1.0-1.01.0-1.0-1.0-1.0-1.2-0.40.0
Conditioned locomotion0.30.40.70.40.70.70.70.70.6-0.70.7-0.8-0.70.7-0.5-0.6-0.8-0.1-0.70.0
Patch foraging indifference point 0 sec0.91.41.9-1.2-1.3-1.3-1.3-1.3-1.31.3-1.31.41.3-1.31.31.31.20.90.30.0
Patch foraging indifference point AUC0.10.10.4-0.5-0.3-0.3-0.3-0.3-0.20.3-0.30.40.2-0.3-0.1-0.00.20.70.20.0
Delay disc. indifference point, 0s delay0.00.00.1-0.00.20.20.20.20.2-0.20.2-0.2-0.20.2-0.3-0.2-0.20.3-0.10.0
Delay disc. indifference point, 16s delay1.11.22.41.21.11.11.01.01.1-1.01.0-1.0-1.11.0-1.1-1.0-0.9-1.3-1.50.0
Delay disc. indifference point, 2s delay0.30.40.70.60.60.60.60.60.6-0.60.6-0.5-0.60.6-0.8-0.8-0.5-0.6-0.90.0
Delay disc. indifference point, 24s delay1.01.02.11.10.91.00.90.91.0-0.90.9-0.9-1.00.9-1.1-1.0-0.8-1.2-1.50.0
Delay disc. indifference point, 4s delay2.12.23.01.51.61.61.51.51.6-1.51.5-1.5-1.61.5-1.7-1.7-1.4-1.3-1.50.0
Delay disc. indifference point, 8s delay2.12.23.01.51.51.51.51.51.6-1.51.5-1.5-1.51.5-1.7-1.7-1.3-1.3-1.70.0
Indifference point function ln k0.20.31.20.60.50.40.50.50.4-0.50.6-0.6-0.50.6-0.2-0.3-0.7-1.1-0.90.0
Indifference point function log k0.20.31.20.60.50.40.50.50.4-0.50.6-0.6-0.50.6-0.2-0.3-0.7-1.1-0.90.0
Patch foraging total patch changes 0 sec1.11.72.2-1.3-1.4-1.4-1.4-1.4-1.41.4-1.41.51.5-1.41.51.51.31.10.70.0
Patch foraging total patch changes 12 sec0.81.11.6-1.0-1.1-1.1-1.1-1.1-1.11.1-1.11.31.1-1.10.81.01.11.10.70.0
Patch foraging total patch changes 18 sec2.63.34.7-2.0-1.8-1.8-1.8-1.8-1.91.9-1.81.91.9-1.91.81.91.82.21.50.0
Patch foraging total patch changes 24 sec2.93.64.5-2.1-2.0-2.0-2.0-2.0-2.02.0-1.92.01.9-1.91.81.92.02.11.90.0
Patch foraging total patch changes 6 sec0.10.20.3-0.4-0.4-0.4-0.4-0.4-0.40.4-0.40.60.4-0.50.20.30.40.4-0.10.0
Patch foraging time to switch 0 sec0.10.20.40.60.50.40.40.40.5-0.40.4-0.5-0.40.4-0.4-0.4-0.2-0.50.00.0
Patch foraging water rate 0 sec0.10.20.4-0.7-0.5-0.5-0.4-0.4-0.50.4-0.40.40.5-0.40.60.50.20.50.40.0
Patch foraging water rate 12 sec0.30.40.8-0.8-0.7-0.7-0.6-0.6-0.70.6-0.60.60.6-0.60.70.70.40.70.90.0
Patch foraging water rate 18 sec0.00.00.1-0.2-0.1-0.1-0.1-0.1-0.10.0-0.0-0.0-0.00.10.0-0.00.0-0.10.40.0
Patch foraging water rate 24 sec0.71.01.4-1.0-1.0-1.0-1.0-1.0-1.01.0-1.01.11.0-1.01.00.80.81.21.10.0
Patch foraging water rate 6 sec0.20.30.5-0.7-0.7-0.7-0.7-0.7-0.70.6-0.60.50.6-0.60.60.60.60.50.40.0
Seeking ratio, delayed vs. immediate footshock2.22.63.41.31.81.81.81.81.8-1.81.8-1.8-1.71.8-1.7-1.9-1.7-0.7-0.80.0
Distance traveled before self-admin0.00.00.00.0-0.1-0.1-0.1-0.1-0.10.1-0.10.10.1-0.10.10.10.1-0.2-0.10.0
Distance traveled after self-admin0.20.20.80.60.50.40.50.50.5-0.50.5-0.4-0.50.5-0.3-0.3-0.5-0.9-0.60.0
Extensor digitorum longus weight0.10.60.70.80.80.80.80.80.8-0.80.8-0.8-0.80.8-0.8-0.8-0.9-0.7-0.40.0
Bone: elastic displacement0.10.10.4-0.3-0.2-0.2-0.2-0.2-0.20.2-0.20.20.2-0.20.30.30.20.30.70.0
Bone: elastic work0.40.61.1-0.8-0.8-0.8-0.8-0.8-0.80.8-0.70.70.7-0.70.80.80.70.51.00.0
Bone: endosteal estimation0.10.20.3-0.4-0.4-0.4-0.4-0.4-0.40.4-0.40.40.5-0.50.50.50.50.3-0.20.0
Bone: endosteal perimeter1.22.43.51.71.61.61.61.61.5-1.61.6-1.6-1.61.6-1.5-1.5-1.7-1.9-1.70.0
Epididymis fat weight0.30.82.8-1.0-0.8-0.8-0.8-0.8-0.80.8-0.80.80.8-0.80.70.60.91.31.70.0
Delta time in closed arm before/after self-admin0.10.10.10.20.40.30.40.40.3-0.40.4-0.4-0.30.4-0.2-0.2-0.3-0.10.00.0
Delta time in open arm before/after self-admin0.30.30.4-0.1-0.5-0.5-0.5-0.5-0.50.5-0.50.60.5-0.50.60.60.5-0.4-0.50.0
Diff in mean of infusions in LGA sessions0.00.00.6-0.10.10.10.10.10.1-0.10.1-0.1-0.00.1-0.0-0.1-0.00.20.80.0
Delay discount exponential model param2.52.73.6-1.6-1.7-1.7-1.7-1.7-1.71.7-1.71.61.7-1.71.91.91.51.41.80.0
Extinction: sum of active levers before priming0.00.00.1-0.2-0.1-0.1-0.1-0.1-0.10.1-0.10.20.1-0.10.2-0.00.10.3-0.00.0
Active lever presses in extinction session 60.30.30.5-0.4-0.6-0.5-0.5-0.5-0.60.5-0.50.60.6-0.60.60.40.50.1-0.70.0
Bone: final force0.71.22.2-1.0-1.2-1.2-1.2-1.2-1.21.1-1.11.11.1-1.11.11.01.10.81.50.0
Bone: final moment1.01.62.9-1.2-1.3-1.3-1.3-1.3-1.31.3-1.31.31.3-1.31.31.21.30.91.70.0
Food consumed during 24 hour testing period1.31.51.8-1.3-1.3-1.3-1.3-1.3-1.41.3-1.31.21.3-1.21.31.31.21.21.20.0
Glucose0.30.41.0-0.8-0.6-0.6-0.6-0.6-0.60.6-0.60.60.6-0.60.50.60.61.00.40.0
Heart weight2.43.46.3-1.9-1.9-1.9-1.9-1.9-1.91.9-1.91.91.9-1.91.81.91.71.62.50.0
Delay discount hyperbolic model param2.52.63.6-1.6-1.7-1.7-1.7-1.7-1.71.7-1.61.61.7-1.61.91.91.51.41.80.0
Intermittent access intake day 1-15 change0.60.62.11.10.70.70.80.80.7-0.70.8-0.7-0.70.7-0.6-0.7-0.8-1.4-0.40.0
Intermittent access intake escalation0.50.52.11.00.60.60.70.70.6-0.60.7-0.6-0.60.6-0.5-0.5-0.7-1.5-0.50.0
Intermittent access intake escalation 20.10.10.60.3-0.2-0.2-0.1-0.1-0.20.1-0.10.00.2-0.10.30.20.1-0.80.20.0
Intermitt. access day 1 inactive lever presses0.00.00.10.00.10.10.10.10.0-0.10.1-0.3-0.10.1-0.1-0.1-0.0-0.1-0.20.0
Intermitt. access day 15 inactive lever presses0.70.81.41.00.90.90.90.90.9-0.90.9-0.8-0.90.9-1.0-1.0-0.8-1.2-0.60.0
Intermitt. access escalation Index0.00.00.60.0-0.0-0.0-0.0-0.0-0.00.0-0.0-0.10.0-0.00.10.00.0-0.2-0.70.0
Intermittent access day 1 total infusions0.00.00.10.00.10.10.20.20.1-0.20.2-0.2-0.10.2-0.0-0.1-0.2-0.1-0.30.0
Intermittent access day 15 total infusions0.40.41.60.80.60.60.60.60.5-0.60.6-0.6-0.50.6-0.4-0.5-0.7-1.3-0.70.0
Intermittent access terminal intake (last 3 days)0.20.21.00.60.40.40.40.40.3-0.40.4-0.4-0.30.4-0.1-0.3-0.5-1.0-0.80.0
Intermittent access total infusions0.50.61.30.80.70.70.80.80.7-0.70.8-0.8-0.70.8-0.4-0.6-0.8-1.1-1.10.0
Intermittent access day 1 locomotion0.10.10.20.20.30.30.40.40.3-0.30.4-0.3-0.30.4-0.2-0.3-0.3-0.2-0.40.0
Intermittent access day 15 total locomotion0.60.62.00.80.80.80.80.80.7-0.80.8-0.9-0.70.8-0.6-0.6-0.8-1.0-1.40.0
Intermittent access total locomotion1.11.32.21.11.21.21.21.21.1-1.21.2-1.2-1.11.2-1.0-1.1-1.2-1.1-1.50.0
Intermittent access standard deviation0.20.20.5-0.2-0.5-0.5-0.4-0.4-0.50.5-0.40.50.5-0.40.60.60.4-0.20.70.0
Left kidney weight0.51.52.0-1.4-1.4-1.4-1.4-1.4-1.41.3-1.31.41.2-1.21.11.11.11.11.00.0
Right kidney weight0.10.30.5-0.5-0.6-0.6-0.7-0.7-0.60.6-0.60.70.5-0.50.40.40.40.2-0.20.0
Cocaine induced anxiety0.50.60.80.90.80.80.80.80.8-0.80.8-0.8-0.80.8-0.9-0.9-0.8-0.9-0.50.0
Post-drug Anxiety0.20.20.40.60.50.50.50.50.6-0.50.5-0.4-0.50.5-0.7-0.7-0.4-0.5-0.10.0
Baseline Anxiety0.10.10.40.40.40.40.40.40.4-0.40.4-0.3-0.40.4-0.4-0.4-0.3-0.5-0.60.0
Tail length6.419.522.4-4.5-4.7-4.7-4.7-4.7-4.64.7-4.74.74.7-4.74.54.64.74.03.70.0
Length with tail8.932.737.0-5.8-6.1-6.1-6.1-6.1-6.06.1-6.16.16.0-6.05.95.95.95.15.00.0
Length without tail6.113.314.9-3.7-3.8-3.8-3.8-3.8-3.93.8-3.83.83.8-3.83.93.73.63.53.70.0
Times rat made contact with spout0.40.50.9-0.7-0.7-0.7-0.7-0.7-0.70.7-0.70.70.7-0.70.60.60.70.70.90.0
Lifetime Intake0.30.40.80.60.60.60.70.70.6-0.60.7-0.7-0.60.7-0.4-0.5-0.7-0.8-0.90.0
Liver weight, left0.10.10.3-0.3-0.3-0.3-0.3-0.3-0.20.3-0.30.40.3-0.40.20.20.50.5-0.40.0
Liver weight, right1.11.82.4-1.5-1.4-1.4-1.5-1.5-1.41.5-1.51.41.4-1.41.21.21.61.51.00.0
Locomotor activity5.58.711.9-2.9-3.1-3.1-3.1-3.1-3.13.1-3.13.13.1-3.03.43.42.82.52.50.0
Locomotor testing distance5.28.712.0-3.0-3.1-3.1-3.1-3.0-3.13.1-3.03.13.1-3.03.43.52.92.62.20.0
Locomotor testing rearing0.30.41.1-0.6-0.6-0.6-0.6-0.5-0.60.6-0.60.60.7-0.61.01.00.60.50.40.0
Locomotion in novel chamber0.20.20.40.10.50.50.50.50.5-0.50.5-0.5-0.50.5-0.5-0.5-0.60.30.60.0
Locomotion in novel chamber post-restriction0.81.02.0-1.2-1.0-1.0-1.0-1.0-1.01.0-1.01.01.0-1.00.91.00.81.41.40.0
Fecal boli incidents, locomotor time 10.40.51.4-0.9-0.7-0.6-0.6-0.6-0.70.6-0.60.70.6-0.60.60.60.60.91.20.0
Change in fecal boli incidents, locomotor task0.10.10.6-0.3-0.2-0.2-0.1-0.1-0.10.2-0.20.20.2-0.20.30.10.20.80.60.0
Time >=10cm from walls, locomotor time 10.10.10.30.40.30.30.30.30.3-0.30.3-0.3-0.30.3-0.2-0.3-0.3-0.3-0.50.0
Bouts of movement, locomotor time 10.00.00.2-0.3-0.1-0.1-0.1-0.1-0.10.1-0.10.10.1-0.10.30.10.10.50.30.0
Total resting periods, locomotor time 10.10.10.4-0.4-0.1-0.1-0.1-0.1-0.10.1-0.10.00.1-0.10.30.10.10.60.40.0
Rest time, locomotor task time 10.50.50.80.30.80.80.80.80.8-0.80.8-0.8-0.80.8-0.7-0.9-0.90.3-0.10.0
Distance moved, locomotor task time 11.51.62.1-1.2-1.4-1.4-1.4-1.4-1.41.4-1.41.31.4-1.31.31.41.40.91.20.0
Vertical activity count, locomotor time 10.80.81.0-0.9-0.9-0.9-1.0-1.0-0.90.9-0.90.90.9-0.90.90.91.00.81.00.0
Time >=10cm from walls, locomotor time 21.51.62.0-1.4-1.3-1.3-1.3-1.3-1.31.3-1.31.31.3-1.31.41.31.31.31.10.0
Bouts of movement, locomotor time 20.00.00.00.0-0.1-0.1-0.1-0.0-0.10.1-0.00.10.1-0.00.10.10.0-0.20.10.0
Total resting periods, locomotor time 20.00.00.20.30.20.20.20.20.2-0.20.2-0.2-0.20.2-0.2-0.1-0.2-0.4-0.10.0
Rest time, locomotor task time 20.00.00.1-0.00.20.20.20.20.2-0.20.2-0.2-0.20.2-0.3-0.3-0.20.40.30.0
Distance moved, locomotor task time 20.80.91.2-0.9-1.1-1.1-1.1-1.1-1.11.1-1.11.01.0-1.01.01.01.10.40.60.0
Vertical activity count, locomotor time 20.00.10.1-0.3-0.3-0.3-0.3-0.3-0.30.3-0.30.20.2-0.20.20.10.3-0.1-0.10.0
Light reinforcement 10.61.11.5-1.1-1.1-1.1-1.1-1.1-1.11.1-1.11.21.0-1.10.91.01.11.00.90.0
Light reinforcement 20.10.20.80.50.30.30.30.30.4-0.30.3-0.3-0.40.4-0.4-0.5-0.4-0.6-0.90.0
Bone: marrow area0.10.20.3-0.4-0.5-0.5-0.4-0.4-0.50.5-0.50.50.5-0.50.60.50.50.3-0.10.0
Bone: maximum diameter0.40.81.31.00.90.90.90.90.9-0.90.9-0.9-0.90.9-0.8-0.9-1.0-1.1-0.40.0
Bone: maximum force0.61.11.2-0.9-1.1-1.1-1.1-1.1-1.11.1-1.11.11.1-1.11.11.01.10.71.10.0
Bone: maximum moment0.71.21.5-1.0-1.2-1.2-1.2-1.2-1.21.2-1.21.21.2-1.21.21.11.20.71.20.0
Mean time between licks in bursts1.01.51.91.11.31.31.31.31.2-1.31.3-1.4-1.31.3-1.1-1.1-1.4-1.1-1.10.0
Mean num. licks in bursts0.50.60.8-0.7-0.8-0.8-0.9-0.9-0.90.8-0.90.80.8-0.80.70.70.80.60.20.0
Cd content in liver2.52.83.8-1.6-1.6-1.6-1.6-1.6-1.71.7-1.71.71.8-1.81.81.81.71.81.90.0
Co content in liver0.10.10.60.3-0.1-0.1-0.1-0.1-0.10.1-0.10.10.1-0.10.30.30.1-0.8-0.40.0
Cu content in liver4.04.97.1-2.5-2.2-2.2-2.2-2.2-2.32.2-2.22.22.3-2.22.32.32.22.72.20.0
Fe content in liver2.02.43.7-1.5-1.4-1.4-1.4-1.4-1.51.5-1.51.51.6-1.61.61.61.51.91.90.0
K content in liver0.70.71.1-1.0-0.8-0.8-0.8-0.8-0.80.8-0.80.80.7-0.70.70.70.81.10.90.0
Mg content in liver0.00.00.0-0.1-0.00.00.00.0-0.0-0.10.1-0.1-0.10.2-0.1-0.1-0.10.0-0.00.0
Mn content in liver0.50.50.7-0.8-0.9-0.9-0.8-0.8-0.90.8-0.80.70.7-0.70.80.80.70.4-0.10.0
Na content in liver0.40.40.6-0.6-0.6-0.6-0.6-0.6-0.60.7-0.70.70.7-0.80.60.70.70.70.30.0
Rb content in liver1.31.62.4-1.0-1.2-1.2-1.2-1.2-1.21.3-1.31.41.4-1.51.61.51.41.21.30.0
Se content in liver0.00.10.3-0.3-0.2-0.1-0.2-0.2-0.10.2-0.20.20.1-0.1-0.2-0.10.20.40.50.0
Sr content in liver0.00.00.0-0.1-0.0-0.0-0.0-0.0-0.0-0.00.0-0.1-0.10.2-0.1-0.1-0.1-0.1-0.10.0
Zn content in liver4.34.86.7-2.5-2.2-2.2-2.2-2.2-2.32.2-2.22.12.2-2.12.32.32.12.62.30.0
Bone: minimum diameter0.40.71.50.90.80.80.80.80.8-0.80.8-0.8-0.80.8-0.7-0.8-0.8-1.2-0.90.0
Time in familiar zone, hab. session 11.11.01.51.21.11.11.11.11.1-1.11.1-1.0-1.01.0-0.9-0.9-1.0-1.2-0.70.0
Time in novel zone, hab. session 10.50.50.6-0.7-0.8-0.8-0.8-0.8-0.70.8-0.80.80.7-0.70.50.50.80.60.60.0
Total zone transitions, hab. session 10.40.50.8-0.9-0.9-0.9-0.9-0.9-0.90.8-0.80.70.7-0.70.70.70.70.50.10.0
Total locomotion distance, hab. session 10.20.30.5-0.7-0.6-0.6-0.6-0.6-0.60.5-0.50.50.5-0.40.40.50.50.60.30.0
Locomotion velocity, hab. session 10.20.30.5-0.7-0.6-0.6-0.6-0.6-0.60.6-0.60.50.5-0.50.50.50.50.60.20.0
Time in familiar zone, hab. session 20.40.40.60.70.70.70.80.80.7-0.70.7-0.8-0.70.7-0.5-0.5-0.8-0.7-0.20.0
Time in novel zone, hab. session 20.00.00.1-0.1-0.2-0.2-0.2-0.2-0.20.2-0.20.20.2-0.20.20.20.20.1-0.30.0
Total zone transitions, hab. session 20.00.00.1-0.3-0.2-0.2-0.2-0.2-0.20.1-0.10.00.10.00.10.10.0-0.1-0.00.0
Total locomotion distance, hab. session 20.20.30.6-0.7-0.6-0.5-0.5-0.5-0.60.5-0.50.40.4-0.40.40.50.40.70.50.0
Locomotion velocity, hab. session 20.10.20.4-0.6-0.4-0.4-0.4-0.4-0.40.4-0.40.30.3-0.30.30.30.30.60.40.0
Novel to familiar place preference ratio0.80.81.1-1.1-0.9-0.9-0.9-0.9-1.00.9-0.90.90.9-0.91.01.00.91.0-0.20.0
Novelty place preference0.80.81.1-1.0-0.9-0.9-0.9-0.9-1.00.9-0.90.90.9-0.90.91.00.91.0-0.30.0
Time in novel zone, NPP test1.01.01.4-1.2-1.1-1.1-1.1-1.1-1.11.1-1.11.01.1-1.11.11.11.01.1-0.00.0
Total zone transitions, NPP test1.72.43.4-1.8-1.8-1.7-1.7-1.7-1.81.6-1.61.51.5-1.41.61.61.51.40.90.0
Total locomotion distance, NPP test0.81.11.7-1.3-1.1-1.1-1.1-1.1-1.11.1-1.11.01.0-1.01.01.01.01.21.10.0
Locomotion velocity, NPP test0.81.21.8-1.4-1.2-1.2-1.2-1.2-1.21.1-1.11.01.0-1.01.01.11.01.21.00.0
Intraocular pressure1.21.72.3-1.3-1.3-1.3-1.3-1.3-1.31.3-1.31.31.4-1.41.41.41.31.51.30.0
Delta distance traveled before/after self-admin0.20.20.60.60.40.40.40.40.4-0.40.4-0.4-0.50.4-0.4-0.3-0.5-0.8-0.60.0
Delta ambulatory time before/after self-admin0.20.20.5-0.4-0.5-0.6-0.5-0.5-0.50.5-0.50.50.5-0.50.70.70.50.00.10.0
Parametrial fat weight1.01.92.4-1.5-1.5-1.5-1.5-1.5-1.41.5-1.51.51.4-1.41.31.31.41.41.00.0
Pavlov. Cond. lever latency5.16.57.7-2.5-2.7-2.7-2.7-2.7-2.62.7-2.72.82.7-2.82.62.62.82.41.90.0
Pavlov. Cond. magazine entry latency6.38.19.33.03.03.03.03.02.9-3.03.0-3.0-3.03.0-2.9-2.9-3.0-3.0-2.20.0
Pavlov. Cond. change in total contacts1.51.62.01.31.41.41.41.41.4-1.41.4-1.4-1.31.4-1.2-1.2-1.4-1.1-0.70.0
Pavlov. Cond. index score6.27.99.32.83.03.03.03.02.9-3.03.0-3.0-3.03.0-2.8-2.8-3.0-2.7-2.00.0
Pavlov. Cond. latency score6.17.89.12.82.92.93.03.02.9-3.03.0-3.0-3.03.0-2.8-2.8-3.0-2.7-2.10.0
Pavlov. Cond. lever contacts3.03.54.41.82.02.02.02.01.9-2.02.0-2.1-2.02.1-1.9-1.9-2.1-1.7-1.30.0
Pavlov. Cond. magazine entry number7.18.910.2-3.1-3.1-3.1-3.2-3.2-3.13.2-3.23.23.1-3.23.03.03.23.02.30.0
Pavlov. Cond. intertrial magazine entries0.40.50.6-0.6-0.7-0.7-0.7-0.7-0.70.7-0.70.80.7-0.70.80.80.80.50.30.0
Pavlov. Cond. lever-magazine prob. diff.5.56.88.12.62.82.82.82.82.7-2.82.8-2.9-2.82.8-2.6-2.6-2.9-2.5-1.70.0
Pavlov. Cond. response bias6.88.29.62.93.03.03.03.13.0-3.13.1-3.1-3.03.1-2.9-2.9-3.1-2.8-2.00.0
Pavlov. Cond. lever latency0.40.50.80.90.80.80.70.70.8-0.70.7-0.6-0.70.6-0.8-0.8-0.6-0.7-0.70.0
Pavlov. Cond. magazine entry latency0.10.20.30.20.40.40.40.40.3-0.40.4-0.6-0.50.5-0.3-0.3-0.5-0.4-0.10.0
Pavlov. Cond. change in total contacts2.33.14.1-2.0-1.9-1.9-1.8-1.8-1.91.8-1.81.61.8-1.71.91.91.71.81.90.0
Pavlov. Cond. index score0.10.10.3-0.5-0.3-0.3-0.3-0.2-0.30.2-0.20.10.2-0.10.30.30.10.30.60.0
Pavlov. Cond. latency score0.00.00.2-0.4-0.2-0.2-0.2-0.2-0.20.2-0.10.00.1-0.00.20.20.10.20.50.0
Pavlov. Cond. lever contacts0.91.21.8-1.4-1.2-1.2-1.1-1.1-1.21.1-1.11.01.1-1.01.11.11.01.21.00.0
Pavlov. Cond. magazine entry number0.40.40.8-0.5-0.7-0.7-0.7-0.7-0.60.7-0.70.90.7-0.80.60.60.80.70.30.0
Pavlov. Cond. intertrial magazine entries0.30.40.90.80.70.70.70.70.7-0.60.6-0.5-0.50.5-0.5-0.5-0.6-0.8-0.90.0
Pavlov. Cond. lever-magazine prob. diff.0.00.10.3-0.4-0.3-0.2-0.2-0.2-0.30.2-0.20.00.1-0.10.20.20.10.20.50.0
Pavlov. Cond. response bias0.00.10.2-0.5-0.3-0.3-0.2-0.2-0.30.2-0.20.00.2-0.10.30.30.10.30.40.0
Time in closed arm before self-admin1.51.72.0-1.2-1.4-1.4-1.4-1.4-1.41.4-1.41.41.4-1.41.41.41.21.01.20.0
Time in closed arm after self-admin0.00.10.6-0.1-0.1-0.1-0.1-0.1-0.20.1-0.10.10.1-0.10.20.20.10.20.80.0
Time in open arm before self-admin1.01.11.50.91.11.11.11.11.1-1.11.1-1.2-1.11.1-1.2-1.2-0.9-0.8-0.90.0
Time in open arm after self-admin0.40.42.90.80.40.40.40.40.4-0.40.4-0.4-0.40.4-0.4-0.4-0.4-1.2-1.70.0
Bone: periosteal estimation0.00.00.10.0-0.1-0.1-0.1-0.1-0.10.1-0.10.10.2-0.10.20.20.1-0.3-0.00.0
Bone: periosteal perimeter1.22.03.21.61.41.41.41.41.4-1.41.4-1.4-1.41.4-1.3-1.4-1.5-1.8-1.30.0
Bone: post-yield work0.00.00.0-0.2-0.2-0.2-0.2-0.2-0.20.2-0.20.20.2-0.20.20.20.1-0.0-0.00.0
Progressive ratio test 1 active lever presses0.00.00.2-0.00.10.10.10.10.0-0.10.1-0.1-0.00.10.10.0-0.2-0.0-0.40.0
Progressive ratio test 1 breakpoint0.00.00.20.10.20.20.20.20.2-0.20.2-0.2-0.20.2-0.0-0.1-0.2-0.1-0.50.0
Progressive ratio test 1 inactive lever presses0.30.30.50.50.70.70.70.70.6-0.70.7-0.5-0.60.7-0.6-0.7-0.7-0.4-0.10.0
Progressive ratio test 2 active lever presses0.91.01.41.01.01.01.01.01.0-1.01.0-1.0-1.01.0-0.9-0.9-1.1-1.1-1.20.0
Progressive ratio test 2 breakpoint0.70.81.10.90.90.91.01.00.9-1.01.0-1.0-0.91.0-0.8-0.9-1.0-1.0-1.00.0
Progressive ratio test 2 inactive lever presses2.02.43.51.61.61.61.61.61.5-1.61.6-1.6-1.61.6-1.4-1.5-1.6-1.9-1.20.0
Incentive Sensitization - Responses1.61.71.91.31.31.31.31.31.3-1.31.3-1.4-1.31.3-1.3-1.3-1.4-1.2-1.20.0
Incentive Sensitization - Breakpoint1.61.61.91.31.31.31.31.31.3-1.31.3-1.4-1.31.3-1.3-1.3-1.4-1.3-1.20.0
Sum of active levers in priming session hrs 5-60.40.40.6-0.7-0.7-0.7-0.7-0.7-0.70.7-0.70.70.7-0.70.70.50.70.70.20.0
Progressive ratio3.43.95.3-2.1-2.0-2.0-2.0-2.0-2.02.0-2.02.02.0-2.02.02.12.02.32.10.0
Food seeking constrained by brief footshock0.81.01.91.21.01.01.01.00.9-1.01.0-1.0-1.01.0-0.9-0.8-1.1-1.4-1.30.0
Seeking ratio, punishment vs. effort5.46.69.12.82.62.62.62.62.6-2.62.6-2.6-2.62.6-2.5-2.6-2.7-3.0-2.60.0
Retroperitoneal fat weight0.51.72.1-1.2-1.4-1.4-1.5-1.5-1.41.4-1.41.51.3-1.41.21.21.41.01.00.0
Reaction time number correct0.30.41.10.80.70.60.70.70.6-0.60.7-0.6-0.60.6-0.4-0.6-0.8-1.0-0.90.0
Reaction time mean minus median0.00.10.2-0.3-0.2-0.2-0.2-0.2-0.20.2-0.20.20.1-0.10.20.20.10.40.30.0
Reaction time mean minus median AUC0.20.31.0-0.7-0.5-0.5-0.5-0.5-0.50.5-0.50.50.5-0.50.50.50.41.00.70.0
Reaction time num false alarms0.30.41.40.80.60.60.60.60.6-0.60.6-0.6-0.50.5-0.4-0.4-0.6-1.2-1.00.0
Reaction time num false alarms AUC0.10.20.90.60.20.20.20.20.3-0.20.2-0.2-0.20.2-0.1-0.1-0.2-0.9-0.90.0
Reaction time trials correct on left0.30.41.10.80.70.60.70.70.6-0.60.7-0.6-0.60.6-0.4-0.6-0.8-1.0-0.90.0
Reaction time trials on left0.30.51.10.80.70.70.70.70.7-0.70.7-0.7-0.60.6-0.4-0.6-0.8-1.1-0.90.0
Reaction time mean0.00.00.1-0.2-0.1-0.1-0.1-0.1-0.10.1-0.10.10.2-0.10.20.30.10.30.00.0
Reaction time mean AUC0.00.00.0-0.1-0.0-0.0-0.0-0.0-0.00.0-0.00.10.1-0.00.10.20.00.2-0.20.0
Median of all reaction times0.00.00.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.10.10.2-0.20.20.30.20.1-0.10.0
Reaction time omissions0.20.20.30.60.60.60.50.50.6-0.50.5-0.4-0.40.4-0.4-0.4-0.4-0.2-0.40.0
Reaction time false alarm rate0.00.00.30.30.10.10.10.10.2-0.10.1-0.1-0.10.1-0.2-0.1-0.1-0.5-0.50.0
Reaction time premature initiation rate2.02.73.3-1.7-1.7-1.7-1.7-1.7-1.71.7-1.71.81.7-1.71.81.61.61.61.50.0
Reaction time premature initiations0.91.31.9-1.1-1.2-1.2-1.2-1.2-1.21.2-1.21.31.2-1.21.41.21.00.80.80.0
Std. dev. reaction times0.10.10.3-0.4-0.4-0.4-0.3-0.3-0.40.4-0.30.40.4-0.30.50.50.20.50.10.0
Reaction time trials completed0.30.51.10.80.70.70.70.70.7-0.70.7-0.7-0.60.6-0.4-0.6-0.8-1.1-0.90.0
Reaction time trials AUC0.40.61.30.90.80.80.80.80.8-0.80.8-0.8-0.70.7-0.5-0.7-0.9-1.1-1.00.0
Run reversals in cocaine runway, females1.71.72.61.51.31.31.31.31.3-1.31.3-1.3-1.31.3-1.4-1.3-1.2-1.6-1.30.0
Run reversals in cocaine runway, males0.60.61.2-0.7-0.7-0.8-0.8-0.8-0.70.7-0.70.80.7-0.70.80.70.80.61.10.0
Latency to leave start box in cocaine runway0.50.51.6-0.8-0.6-0.6-0.6-0.6-0.60.6-0.60.60.6-0.60.60.50.81.11.30.0
Latency to leave start box in cocaine runway, F1.31.42.8-1.2-1.2-1.2-1.2-1.2-1.31.2-1.21.21.2-1.21.31.11.11.01.70.0
Latency to leave start box in cocaine runway, M0.30.30.50.20.60.60.60.60.6-0.60.6-0.6-0.60.6-0.7-0.6-0.20.4-0.10.0
Std. dev. time between licks in bursts3.64.35.32.12.22.22.32.32.2-2.22.3-2.3-2.12.2-1.9-1.9-2.3-2.2-1.50.0
Total sessions with >9 infusions0.10.10.3-0.00.20.20.30.30.2-0.30.3-0.1-0.20.20.10.0-0.30.10.60.0
Short access day 1 total inactive lever presses3.23.64.41.82.02.02.12.12.0-2.12.1-2.0-2.02.1-1.8-1.8-2.0-1.7-1.40.0
Short access day 10 total inactive lever presses0.00.00.20.10.10.10.10.10.1-0.10.10.0-0.10.1-0.2-0.20.0-0.20.50.0
Short access day 1 total infusions0.70.81.00.71.01.01.01.01.0-1.01.0-0.9-1.01.0-0.9-0.9-1.0-0.4-0.40.0
Short access day 10 total infusions0.10.10.20.10.20.20.20.30.1-0.20.3-0.3-0.20.30.00.0-0.3-0.3-0.50.0
Short access total infusions0.40.50.80.60.70.70.80.80.7-0.80.8-0.8-0.70.8-0.6-0.6-0.8-0.6-0.90.0
Short access day 1 locomotion0.00.00.1-0.00.20.20.20.20.2-0.20.2-0.3-0.20.2-0.1-0.1-0.30.20.10.0
Short access day 10 total locomotion0.00.10.3-0.4-0.2-0.2-0.1-0.1-0.20.1-0.10.00.2-0.10.30.20.10.60.10.0
Short access total locomotion0.00.00.2-0.20.10.10.10.10.0-0.10.1-0.3-0.10.10.10.0-0.20.5-0.00.0
One hour access (0.3 mA shock)0.20.21.40.50.40.40.40.40.3-0.40.4-0.4-0.30.4-0.1-0.2-0.5-0.8-1.20.0
Compulsive drug intake0.00.00.50.10.10.10.10.10.1-0.10.10.0-0.10.1-0.2-0.20.0-0.0-0.70.0
One hour access (shock baseline)0.10.10.60.40.20.20.30.30.2-0.30.3-0.4-0.20.30.0-0.1-0.4-0.8-0.60.0
Social response proportion0.40.50.7-0.5-0.7-0.7-0.8-0.8-0.70.8-0.80.80.8-0.80.60.60.80.40.30.0
Social responses0.30.40.5-0.7-0.7-0.7-0.7-0.7-0.70.7-0.70.70.7-0.70.50.60.60.40.20.0
Social time0.50.71.91.10.80.80.70.70.8-0.80.7-0.7-0.80.8-1.0-0.9-0.6-1.4-0.90.0
Soleus weight3.610.512.3-3.5-3.4-3.4-3.4-3.4-3.43.3-3.33.23.3-3.23.43.43.33.23.30.0
Bone: stiffness0.10.20.3-0.3-0.5-0.5-0.5-0.5-0.40.5-0.50.50.5-0.50.50.40.50.20.30.0
Tibialis anterior weight0.00.00.2-0.2-0.1-0.1-0.1-0.1-0.20.1-0.10.10.1-0.10.10.10.10.10.40.0
Time to tail flick, vehicle, before self-admin2.12.24.4-1.6-1.4-1.4-1.4-1.4-1.41.4-1.41.41.4-1.51.31.31.61.92.10.0
Time to tail flick, vehicle, after self-admin0.50.50.7-0.9-0.7-0.8-0.8-0.8-0.70.7-0.80.70.7-0.70.70.60.60.80.50.0
Time to tail flick, test, before self-admin0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.20.2-0.20.20.1-0.2-0.1-0.10.30.2-0.40.0
Time to tail flick, test, after self-admin0.10.10.30.20.40.40.40.40.4-0.40.4-0.5-0.40.4-0.5-0.6-0.2-0.10.00.0
Delta time to tail flick, vehicle, before/after SA0.50.50.90.70.70.70.70.70.7-0.70.7-0.7-0.80.8-0.7-0.6-0.9-0.8-0.90.0
Delta time to tail flick, test, before/after SA0.30.20.30.40.50.60.60.60.5-0.60.6-0.6-0.50.6-0.5-0.5-0.6-0.3-0.00.0
Tibia length6.016.819.9-4.5-4.4-4.4-4.4-4.4-4.44.3-4.34.24.2-4.14.24.14.13.83.80.0
Ambulatory time before self-admin0.10.10.30.40.20.20.20.20.2-0.20.2-0.2-0.20.2-0.3-0.3-0.2-0.5-0.20.0
Ambulatory time after self-admin0.10.10.40.30.10.10.10.10.2-0.10.1-0.0-0.10.1-0.1-0.1-0.1-0.7-0.50.0
Bone: tissue strength2.92.93.5-1.7-1.8-1.8-1.7-1.7-1.81.8-1.71.71.8-1.71.81.81.71.41.90.0
Total heroin consumption1.11.31.6-1.2-1.2-1.2-1.2-1.2-1.21.2-1.21.21.2-1.21.31.21.10.81.20.0
Bone: trabecular number0.61.03.11.00.90.90.90.90.9-1.01.0-1.0-1.01.0-0.9-0.9-1.0-1.1-1.80.0
Bone: trabecular spacing1.41.83.8-1.3-1.3-1.3-1.4-1.4-1.31.4-1.41.41.4-1.41.21.21.41.31.90.0
Bone: trabecular thickness0.00.00.1-0.2-0.1-0.1-0.1-0.1-0.10.1-0.10.10.1-0.10.00.00.10.2-0.30.0
Bone: trabecular tissue density0.20.30.4-0.5-0.6-0.6-0.6-0.6-0.60.6-0.60.60.5-0.60.50.50.50.40.30.0
Water consumed over 24 hours0.00.00.20.10.10.10.10.10.1-0.10.1-0.2-0.10.1-0.1-0.1-0.2-0.20.40.0
Number of responses in last shaping day0.80.81.51.00.90.90.90.90.9-0.90.9-0.7-0.90.9-0.9-0.9-0.9-1.2-0.70.0