Hub : Genes

Tuba1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr7_131993996_131995751 0.05 0.04 3.5e-05 0.04 0.04 0.04 0.04 1.8e-05 3.5e-05 1.4e-05 2.6e-05
2 Brain gene expression Tuba1b 0.79 0.11 0.0e+00 0.52 0.52 0.52 0.53 5.5e-57 4.2e-56 1.5e-56 4.7e-57
3 IL gene expression Tuba1b 0.87 0.09 0.0e+00 0.4 0.5 0.46 0.5 1.2e-10 5.4e-14 1.1e-12 7.0e-14
4 BLA intron excision ratio chr7_131971419_131972486 0.17 0.14 1.4e-07 0.12 0.13 0.13 0.13 3.7e-07 1.6e-07 2.5e-07 2.4e-07
5 Brain intron excision ratio chr7_131993996_131995751 0.13 0.08 1.3e-14 0.14 0.15 0.14 0.14 4.7e-13 3.8e-14 4.0e-13 3.4e-13
6 Eye gene expression Tuba1b 0.3 0.29 3.4e-03 0.14 0.17 0.14 0.15 3.2e-03 1.3e-03 3.3e-03 2.8e-03
7 Brain intron excision ratio chr7_131971419_131972486 0.1 0.07 2.2e-10 0.09 0.11 0.1 0.1 5.8e-09 2.8e-10 5.6e-10 1.3e-09
8 BLA gene expression Tuba1b 0.21 0.15 3.3e-10 0.15 0.18 0.16 0.16 3.7e-08 7.6e-10 1.0e-08 1.2e-08
9 OFC gene expression Tuba1b 0.75 0.13 0.0e+00 0.47 0.46 0.46 0.46 8.3e-13 2.1e-12 1.5e-12 2.0e-12
10 LHb gene expression Tuba1b 0.82 0.12 0.0e+00 0.47 0.5 0.47 0.48 1.1e-12 9.6e-14 8.4e-13 5.4e-13
11 BLA intron excision ratio chr7_131993996_131995751 0.09 0.09 1.6e-04 0.08 0.07 0.08 0.07 6.6e-05 1.4e-04 4.8e-05 1.2e-04
12 PL gene expression Tuba1b 0.48 0.18 0.0e+00 0.28 0.28 0.27 0.28 2.0e-30 1.1e-30 1.0e-29 2.5e-30
13 Liver gene expression Tuba1b 0.46 0.19 0.0e+00 0.42 0.42 0.42 0.42 1.5e-50 1.1e-49 4.5e-50 2.5e-50
14 IC intron excision ratio chr7_131971419_131972486 0.21 0.24 1.7e-05 0.11 0.11 0.12 0.12 2.3e-05 1.8e-05 1.1e-05 1.3e-05
15 IC intron excision ratio chr7_131993996_131995751 0.16 0.16 4.9e-05 0.1 0.1 0.11 0.1 5.1e-05 4.7e-05 2.7e-05 3.9e-05
16 RMTg gene expression Tuba1b 0.55 0.25 9.6e-12 0.3 0.36 0.33 0.36 9.5e-09 2.2e-10 1.5e-09 1.4e-10
17 NAcc gene expression Tuba1b 0.63 0.13 0.0e+00 0.18 0.18 0.18 0.18 5.2e-27 3.0e-27 6.8e-27 6.1e-27
18 IC gene expression Tuba1b 0.6 0.27 0.0e+00 0.37 0.37 0.38 0.37 2.7e-16 2.7e-16 4.6e-17 1.2e-16
19 pVTA gene expression Tuba1b 0.04 0.04 2.3e-03 0.02 0.01 0.01 0.01 8.1e-03 2.7e-02 8.9e-02 1.9e-02
20 PL intron excision ratio chr7_131971419_131972486 0.06 0.05 5.7e-06 0.05 0.05 0.05 0.05 5.9e-06 6.0e-06 4.5e-06 7.0e-06
21 Adipose gene expression Tuba1b 0.04 0.04 7.4e-05 0.03 0.03 0.04 0.03 1.0e-04 3.5e-04 7.7e-05 2.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density8.816.318.24.24.24.24.2-4.24.24.24.2-4.24.14.14.1-4.0-4.14.14.04.3-3.9-3.9-4.1-0.0
Area under the delay curve0.50.71.20.80.80.90.9-0.90.90.90.9-1.00.71.00.7-0.8-1.11.11.00.6-0.6-0.8-0.9-0.3
BMI with tail6.322.127.04.94.74.84.9-4.94.85.04.9-4.84.65.14.5-4.6-5.25.24.94.3-4.3-4.9-5.00.4
BMI without tail1.05.18.02.42.22.22.4-2.32.22.42.4-2.21.92.51.9-2.0-2.62.72.51.7-1.7-2.8-2.8-1.1
Body weight6.428.134.65.55.45.45.6-5.55.45.65.6-5.45.05.74.9-5.1-5.95.95.74.7-4.8-5.7-5.7-1.1
Weight adjusted by age1.23.44.21.91.91.91.9-1.91.91.92.0-1.91.72.01.7-1.9-2.02.02.11.7-1.6-2.1-1.61.1
Bone surface10.520.724.14.94.84.74.7-4.74.74.74.7-4.84.74.64.6-4.5-4.64.54.54.7-4.4-4.4-4.9-0.3
Bone volume7.915.819.64.34.24.14.1-4.14.14.14.1-4.24.14.04.1-3.9-4.03.93.94.2-3.8-3.7-4.4-0.5
Breakpoint value in progressive ratio session0.81.52.21.21.21.31.3-1.31.31.31.3-1.21.31.21.3-1.5-1.21.21.31.0-1.4-1.3-0.70.5
Number of licking bursts0.20.51.3-0.6-0.8-0.7-0.60.7-0.8-0.6-0.60.8-1.0-0.3-1.00.80.3-0.2-0.3-1.01.10.00.40.5
Context. condit. distance diff. score0.30.41.80.50.50.50.6-0.50.50.50.6-0.50.40.80.3-0.6-0.70.70.70.3-0.4-1.0-0.11.3
Locomotion velocity, session 10.81.01.7-1.0-0.9-1.0-1.01.0-0.9-1.0-1.00.8-0.8-1.1-0.80.91.0-1.0-1.1-0.90.71.30.8-1.3
Locomotion distance, session 12.73.45.5-2.1-1.9-1.8-1.91.8-1.8-1.9-1.91.8-1.6-2.1-1.61.62.1-2.1-2.0-1.61.32.32.3-0.8
Locomotion velocity, session 20.40.55.1-0.6-0.5-0.5-0.50.5-0.5-0.5-0.50.4-0.4-0.8-0.40.50.5-0.5-0.6-0.30.31.00.4-2.3
Locomotion distance, session 22.23.15.5-1.9-1.7-1.7-1.81.8-1.7-1.8-1.81.6-1.6-2.1-1.51.61.9-1.9-1.8-1.41.42.31.9-1.4
Locomotion velocity, session 33.84.46.0-2.2-2.1-2.1-2.22.2-2.2-2.2-2.22.1-2.1-2.3-2.12.12.1-2.1-2.1-2.02.02.51.8-0.9
Locomotion distance, session 34.45.16.6-2.4-2.3-2.3-2.42.4-2.3-2.4-2.42.2-2.2-2.4-2.12.32.5-2.5-2.3-1.82.22.62.1-0.4
Stereotopy head waving bouts, day 31.51.84.61.41.31.31.2-1.21.21.31.2-1.41.31.11.2-1.0-1.21.21.21.5-1.1-0.7-2.1-2.2
Stereotopy head waving duration, day 31.01.26.81.11.01.00.9-0.90.90.90.9-1.01.00.61.0-0.8-0.80.80.71.1-0.9-0.3-1.8-2.6
Locomotion velocity, session 70.20.20.5-0.4-0.3-0.4-0.50.5-0.5-0.5-0.50.3-0.5-0.2-0.50.60.5-0.5-0.3-0.20.70.00.40.4
Locomotion distance, session 71.41.82.8-1.3-1.3-1.3-1.41.5-1.4-1.4-1.41.2-1.5-1.0-1.41.61.4-1.4-1.2-1.11.70.71.51.5
Stereotopy head waving bouts, day 71.51.74.01.51.31.31.3-1.21.21.31.3-1.31.11.31.1-1.1-1.31.31.31.2-1.0-1.3-2.0-1.5
Stereotopy head waving duration, day 71.21.53.21.31.11.11.2-1.21.11.21.2-1.21.11.11.1-1.1-1.21.21.11.0-1.1-1.1-1.8-1.5
Locomotion velocity, session 80.10.11.7-0.1-0.1-0.00.0-0.00.00.00.10.1-0.1-0.0-0.1-0.1-0.20.20.1-0.3-0.10.10.2-1.3
Locomotion distance, session 81.11.63.7-1.5-1.2-1.3-1.31.3-1.3-1.3-1.31.3-1.3-1.2-1.21.11.3-1.3-1.3-1.21.11.31.90.1
Degree of sensitization distance0.50.61.80.80.70.70.7-0.70.70.70.7-0.70.51.00.5-0.6-0.80.80.80.6-0.4-1.3-0.50.8
Degree of sensitization stereotypy0.20.20.90.50.30.30.4-0.30.30.40.4-0.40.20.50.1-0.2-0.60.60.50.1-0.1-0.7-0.9-0.6
Conditioned locomotion0.00.00.20.20.20.20.1-0.10.10.10.1-0.30.20.10.2-0.2-0.10.10.10.5-0.10.2-0.30.1
Cocaine response after cond. corrected0.10.11.3-0.2-0.1-0.1-0.10.1-0.1-0.1-0.10.1-0.1-0.2-0.10.10.1-0.0-0.1-0.10.10.3-0.0-1.1
Cocaine response after cond. not corrected0.50.71.0-0.9-0.8-0.9-0.90.8-0.8-0.8-0.90.9-0.8-0.9-0.80.90.8-0.8-0.9-0.80.71.00.6-1.0
Cocaine response before conditioning3.44.15.3-2.0-2.0-2.1-2.12.1-2.1-2.1-2.22.1-1.9-2.0-1.92.02.2-2.2-2.3-1.91.91.92.00.3
Saline control response0.00.00.10.20.30.20.2-0.20.20.20.1-0.20.30.20.3-0.2-0.10.00.00.2-0.3-0.1-0.20.0
Bone: connectivity density6.410.211.63.43.43.33.3-3.33.33.33.3-3.33.33.23.3-3.2-3.23.23.13.4-3.2-3.0-3.4-0.1
Bone: cortical apparent density0.20.20.5-0.6-0.4-0.4-0.50.5-0.4-0.5-0.50.6-0.3-0.5-0.30.40.6-0.6-0.7-0.10.40.40.70.6
Bone: cortical area10.316.821.74.44.34.24.3-4.24.14.34.3-4.43.94.33.9-4.0-4.44.44.43.8-3.6-4.2-4.70.3
Bone: cortical porosity0.70.81.8-0.8-0.8-0.8-0.90.9-0.8-0.9-1.00.7-0.4-1.1-0.40.71.3-1.3-1.2-0.40.41.30.80.9
Bone: cortical porosity1.01.12.8-0.9-0.9-0.9-1.11.0-0.9-1.1-1.10.8-0.6-1.2-0.60.91.4-1.5-1.3-0.40.61.31.01.7
Bone: cortical thickness4.27.011.82.92.72.62.8-2.72.62.72.8-2.82.22.82.2-2.4-3.13.13.12.1-2.1-2.7-3.4-0.1
Bone: cortical thickness0.20.20.60.50.40.40.4-0.30.30.40.4-0.60.00.70.0-0.1-0.60.60.80.20.1-0.8-0.60.4
Bone: cortical tissue density0.20.30.7-0.7-0.5-0.5-0.60.6-0.5-0.6-0.60.7-0.4-0.6-0.30.50.7-0.7-0.8-0.20.50.50.80.5
Condit. Reinf. active minus inactive responses0.10.10.6-0.1-0.2-0.2-0.20.2-0.2-0.2-0.20.0-0.1-0.5-0.10.20.4-0.4-0.2-0.10.10.6-0.0-0.7
Condit. Reinf. active-inactive response ratio0.30.30.80.50.60.60.5-0.50.60.50.5-0.70.80.20.8-0.6-0.20.20.40.9-0.8-0.1-0.3-0.1
Condit. Reinf. active responses0.60.71.5-0.8-0.8-0.8-0.80.8-0.8-0.8-0.80.7-0.9-1.1-0.90.80.8-0.8-0.7-0.90.81.20.4-1.1
Condit. Reinf. inactive responses2.63.34.5-1.8-2.0-1.9-1.91.9-1.9-1.9-1.81.9-2.1-1.8-2.11.91.6-1.6-1.7-2.11.91.81.4-0.4
Incentive salience index mean0.00.00.30.10.10.20.1-0.10.10.10.2-0.20.0-0.00.0-0.1-0.20.20.30.1-0.10.1-0.2-0.5
Condit. Reinf. lever presses0.10.10.50.30.30.40.4-0.30.30.40.4-0.30.10.20.1-0.3-0.50.60.70.1-0.2-0.2-0.3-0.5
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.20.1-0.0-0.1-0.00.20.3-0.3-0.2-0.00.0-0.00.00.2
Condit. Reinf. active-inactive response ratio0.20.40.7-0.6-0.6-0.6-0.60.6-0.6-0.6-0.60.6-0.6-0.6-0.60.70.6-0.6-0.5-0.80.50.60.2-0.8
Condit. Reinf. active responses0.20.31.5-0.4-0.5-0.5-0.50.5-0.5-0.5-0.50.5-0.4-0.4-0.40.60.7-0.7-0.6-0.30.50.20.51.2
Condit. Reinf. inactive responses0.50.83.1-0.7-0.8-0.8-0.80.8-0.8-0.8-0.90.8-0.7-0.6-0.70.80.9-1.0-1.0-0.60.80.41.01.8
Condit. Reinf. lever presses0.10.23.50.10.10.10.1-0.10.10.10.1-0.00.20.20.2-0.0-0.00.00.10.3-0.0-0.50.11.9
Condit. Reinf. lever reinforcers received0.50.72.5-0.8-0.8-0.8-0.80.8-0.8-0.8-0.90.8-0.7-0.7-0.70.91.0-1.0-0.9-0.70.70.40.91.6
Conditioned reinforcement - actives0.41.72.8-1.2-1.3-1.4-1.31.4-1.4-1.3-1.31.3-1.6-1.2-1.61.71.1-1.1-1.1-1.61.61.10.4-0.6
Conditioned reinforcement - inactives2.05.47.3-2.2-2.4-2.5-2.42.5-2.5-2.4-2.42.2-2.7-2.3-2.72.72.2-2.2-2.1-2.72.72.21.3-0.9
Conditioned locomotion0.10.20.4-0.4-0.4-0.5-0.50.5-0.5-0.5-0.50.5-0.5-0.4-0.60.60.4-0.4-0.5-0.60.60.20.2-0.0
Patch foraging indifference point 0 sec1.23.54.6-1.8-1.9-2.0-1.91.9-2.0-1.9-1.91.9-2.0-1.8-2.12.01.9-1.8-1.8-2.12.11.61.50.2
Patch foraging indifference point AUC0.41.01.7-0.9-1.0-1.1-1.01.1-1.1-1.0-1.10.9-1.1-0.8-1.11.10.9-0.9-1.2-1.01.30.90.7-0.8
Delay disc. indifference point, 0s delay1.11.31.81.21.11.11.1-1.11.11.11.1-1.31.11.11.0-1.1-1.21.21.01.0-1.0-0.8-1.4-1.1
Delay disc. indifference point, 16s delay0.50.81.20.80.80.90.9-0.90.90.90.9-0.90.71.00.7-0.8-1.01.11.10.5-0.6-1.0-1.00.5
Delay disc. indifference point, 2s delay1.11.21.51.01.11.21.2-1.21.21.21.2-1.11.21.11.2-1.2-1.11.11.11.2-1.2-0.9-0.9-0.4
Delay disc. indifference point, 24s delay0.71.11.60.91.11.01.1-1.11.01.11.1-1.10.91.20.9-1.1-1.21.21.20.8-0.8-1.1-0.90.3
Delay disc. indifference point, 4s delay0.30.30.50.40.50.60.6-0.60.60.60.6-0.40.50.50.6-0.6-0.60.60.50.5-0.5-0.5-0.3-0.7
Delay disc. indifference point, 8s delay1.22.13.01.51.31.51.5-1.51.41.51.5-1.61.21.71.2-1.4-1.71.71.71.1-1.1-1.4-1.7-0.3
Indifference point function ln k1.75.05.82.32.32.32.3-2.32.32.32.3-2.32.32.22.3-2.3-2.22.12.42.3-2.4-2.2-2.21.0
Indifference point function log k1.75.05.82.32.32.32.3-2.32.32.32.3-2.32.32.22.3-2.3-2.22.12.42.3-2.4-2.2-2.21.0
Patch foraging total patch changes 0 sec1.23.44.4-1.8-1.9-2.0-1.91.9-2.0-1.9-1.91.9-2.0-1.8-2.02.01.9-1.8-1.8-2.12.11.51.50.3
Patch foraging total patch changes 12 sec2.33.04.6-1.7-1.8-1.9-1.81.8-1.9-1.8-1.81.7-2.0-1.6-2.01.81.6-1.6-1.7-2.12.21.51.4-0.3
Patch foraging total patch changes 18 sec2.25.16.3-2.2-2.3-2.4-2.42.4-2.4-2.4-2.42.2-2.3-2.1-2.32.32.4-2.4-2.5-2.22.42.12.0-0.3
Patch foraging total patch changes 24 sec0.82.63.8-1.5-1.6-1.8-1.71.7-1.8-1.7-1.71.6-1.8-1.5-1.81.81.6-1.6-1.7-1.82.01.41.10.1
Patch foraging total patch changes 6 sec2.23.84.8-1.9-1.9-2.1-2.02.0-2.1-2.0-2.02.0-2.1-1.9-2.12.11.9-1.9-2.0-2.12.21.71.6-0.5
Patch foraging time to switch 0 sec1.03.66.1-2.1-2.0-1.9-1.91.9-1.9-2.0-1.92.0-1.9-2.0-1.81.72.0-2.0-1.8-1.81.91.92.50.5
Patch foraging water rate 0 sec1.45.38.72.52.42.32.4-2.32.32.42.4-2.42.22.42.1-2.1-2.52.52.42.1-2.0-2.2-2.9-0.8
Patch foraging water rate 12 sec1.35.26.12.42.52.42.3-2.32.42.42.3-2.32.32.32.3-2.3-2.22.22.32.4-2.1-2.4-2.30.6
Patch foraging water rate 18 sec0.30.63.40.70.70.60.6-0.60.60.60.7-0.60.50.80.5-0.5-0.70.70.80.5-0.4-1.0-0.71.8
Patch foraging water rate 24 sec2.94.14.62.02.12.12.1-2.12.12.12.1-2.02.12.02.1-2.0-2.02.02.12.0-2.1-2.0-2.10.4
Patch foraging water rate 6 sec4.16.08.22.72.62.52.5-2.52.52.52.5-2.72.52.52.4-2.3-2.42.42.62.5-2.3-2.4-2.90.5
Seeking ratio, delayed vs. immediate footshock0.10.21.70.40.30.30.4-0.30.30.40.4-0.30.30.20.3-0.2-0.40.40.30.2-0.3-0.0-0.9-1.3
Distance traveled before self-admin0.40.91.2-1.1-1.0-0.9-1.01.0-1.0-1.0-0.91.0-1.0-1.0-0.91.01.0-0.9-0.8-0.90.70.81.10.5
Distance traveled after self-admin0.20.31.7-0.5-0.5-0.5-0.50.5-0.5-0.5-0.50.5-0.5-0.7-0.50.50.5-0.5-0.5-0.40.40.70.2-1.3
Extensor digitorum longus weight3.614.421.64.03.83.84.0-3.93.84.04.1-3.83.24.33.2-3.8-4.44.44.52.8-3.4-4.6-3.31.2
Bone: elastic displacement3.84.86.6-2.4-2.2-2.2-2.22.1-2.1-2.2-2.22.4-1.8-2.6-1.81.92.4-2.4-2.5-1.91.62.52.5-0.9
Bone: elastic work0.10.10.5-0.10.20.20.1-0.20.30.10.1-0.10.6-0.20.6-0.40.3-0.3-0.30.6-0.70.40.50.1
Bone: endosteal estimation6.917.019.44.34.34.34.3-4.34.34.34.2-4.44.44.34.4-4.3-4.03.94.14.3-4.1-4.2-3.60.7
Bone: endosteal perimeter6.114.918.44.24.04.04.0-3.93.94.04.0-4.13.74.23.7-3.8-3.93.94.23.6-3.4-4.3-3.81.9
Epididymis fat weight0.62.93.71.81.81.81.7-1.81.81.81.7-1.71.91.61.9-1.7-1.61.61.41.9-1.9-1.3-1.7-1.1
Delta time in closed arm before/after self-admin0.00.00.10.0-0.1-0.1-0.10.1-0.1-0.1-0.10.10.0-0.10.00.10.2-0.2-0.2-0.10.20.2-0.0-0.3
Delta time in open arm before/after self-admin0.91.11.3-1.1-1.1-1.1-1.11.1-1.1-1.1-1.01.0-1.1-1.1-1.11.01.0-1.0-0.9-1.10.90.91.1-1.0
Diff in mean of infusions in LGA sessions0.61.21.51.01.21.11.1-1.21.21.11.1-1.01.21.01.2-1.2-1.01.01.01.1-1.2-0.8-1.0-0.6
Delay discount exponential model param0.50.61.0-0.7-0.8-0.8-0.90.8-0.8-0.9-0.90.8-0.6-0.9-0.70.81.0-1.0-1.0-0.60.60.80.80.2
Extinction: sum of active levers before priming1.11.62.51.41.31.41.4-1.41.41.41.4-1.21.41.21.4-1.4-1.21.21.31.3-1.6-1.0-1.10.0
Active lever presses in extinction session 61.21.21.51.11.11.21.1-1.11.11.11.1-1.21.11.01.1-1.1-1.11.11.21.1-1.0-1.1-0.9-0.2
Bone: final force10.417.119.84.34.34.34.3-4.34.34.34.3-4.54.24.14.2-4.3-4.24.24.24.1-4.2-3.7-4.1-0.3
Bone: final moment11.518.521.34.54.54.54.5-4.54.54.54.5-4.64.54.24.5-4.5-4.34.34.34.3-4.5-3.8-4.2-0.5
Food consumed during 24 hour testing period1.12.13.41.61.51.51.5-1.51.51.51.5-1.51.51.41.5-1.4-1.41.41.41.5-1.3-1.4-1.8-0.8
Glucose0.10.21.00.40.30.40.5-0.40.40.50.5-0.10.10.60.1-0.4-0.70.70.7-0.1-0.1-1.0-0.30.6
Heart weight0.10.10.20.30.30.30.3-0.30.30.30.3-0.20.20.50.2-0.3-0.50.50.40.2-0.2-0.4-0.10.4
Delay discount hyperbolic model param0.50.60.9-0.7-0.7-0.8-0.90.8-0.8-0.9-0.90.8-0.7-0.9-0.70.81.0-1.0-0.9-0.60.70.70.70.4
Intermittent access intake day 1-15 change0.10.69.3-0.3-0.3-0.3-0.30.4-0.4-0.4-0.30.3-0.5-0.0-0.50.40.2-0.2-0.2-0.30.60.00.63.0
Intermittent access intake escalation0.10.47.4-0.0-0.0-0.1-0.10.1-0.1-0.1-0.10.1-0.20.2-0.20.1-0.00.0-0.0-0.00.4-0.20.32.7
Intermittent access intake escalation 20.20.44.7-0.4-0.4-0.4-0.40.5-0.5-0.4-0.40.4-0.6-0.1-0.60.60.3-0.3-0.3-0.40.80.10.42.2
Intermitt. access day 1 inactive lever presses0.11.12.2-1.2-1.0-1.1-1.11.0-1.0-1.1-1.11.2-0.8-1.2-0.80.81.3-1.3-1.3-1.00.60.91.50.6
Intermitt. access day 15 inactive lever presses0.31.41.7-1.2-1.1-1.2-1.21.2-1.3-1.2-1.21.3-1.3-1.1-1.31.31.2-1.1-1.2-1.21.31.11.10.1
Intermitt. access escalation Index0.20.72.30.60.60.80.8-0.80.80.80.8-0.70.70.90.7-0.8-0.70.81.00.7-0.7-1.1-0.01.5
Intermittent access day 1 total infusions0.41.32.1-1.1-1.3-1.2-1.21.2-1.2-1.2-1.21.1-1.3-1.1-1.31.21.0-1.0-1.0-1.41.31.10.7-0.6
Intermittent access day 15 total infusions0.61.43.9-1.0-1.1-1.2-1.11.2-1.2-1.1-1.11.1-1.4-0.8-1.41.20.9-0.8-0.8-1.41.50.70.92.0
Intermittent access terminal intake (last 3 days)1.01.72.6-1.2-1.3-1.4-1.31.4-1.4-1.3-1.31.2-1.5-1.0-1.51.41.2-1.2-1.2-1.41.61.00.91.4
Intermittent access total infusions1.92.33.6-1.4-1.6-1.6-1.51.6-1.7-1.5-1.51.4-1.9-1.3-1.91.61.2-1.2-1.2-1.81.91.11.10.9
Intermittent access day 1 locomotion0.10.10.6-0.3-0.4-0.4-0.30.3-0.4-0.3-0.30.3-0.4-0.2-0.40.30.3-0.3-0.3-0.50.30.10.40.8
Intermittent access day 15 total locomotion0.20.78.6-0.3-0.5-0.6-0.50.6-0.6-0.5-0.50.4-0.6-0.1-0.70.50.4-0.4-0.4-0.70.7-0.10.72.9
Intermittent access total locomotion1.41.63.8-1.1-1.3-1.3-1.31.3-1.3-1.3-1.31.1-1.4-0.9-1.41.31.1-1.1-1.2-1.41.40.71.21.9
Intermittent access standard deviation0.10.72.2-0.8-0.8-0.8-0.70.8-0.8-0.7-0.70.8-1.0-0.5-1.00.60.5-0.5-0.5-0.90.90.41.01.5
Left kidney weight0.54.06.92.02.02.02.0-2.01.92.02.0-2.11.81.81.7-1.8-2.22.22.11.8-1.5-1.7-2.6-2.6
Right kidney weight2.618.121.24.44.44.44.5-4.44.44.54.5-4.34.24.34.2-4.2-4.54.54.44.1-3.9-4.2-4.6-0.7
Cocaine induced anxiety1.54.110.61.92.02.02.0-2.02.02.02.0-1.91.82.21.8-1.8-2.02.12.21.8-1.7-2.3-1.53.3
Post-drug Anxiety3.13.54.61.92.01.91.9-1.91.91.91.9-1.81.82.01.8-1.6-2.02.02.01.8-1.6-1.9-1.72.1
Baseline Anxiety0.10.11.90.10.20.10.1-0.10.10.10.1-0.10.1-0.00.1-0.2-0.20.20.10.1-0.20.2-0.2-1.4
Tail length0.10.35.00.10.10.00.1-0.10.00.10.10.0-0.10.2-0.1-0.0-0.30.30.2-0.30.3-0.6-0.4-2.2
Length with tail1.56.78.52.72.72.62.7-2.62.62.72.7-2.62.32.72.3-2.6-2.92.92.92.1-2.3-2.8-2.9-1.8
Length without tail3.216.920.34.24.34.34.3-4.34.34.34.4-4.34.04.24.0-4.2-4.44.54.53.9-4.0-4.0-4.1-0.4
Times rat made contact with spout0.20.21.6-0.2-0.4-0.3-0.30.3-0.3-0.3-0.20.4-0.5-0.4-0.50.40.1-0.0-0.1-0.60.50.3-0.3-1.3
Lifetime Intake2.32.95.1-1.6-1.8-1.8-1.71.8-1.9-1.7-1.71.6-2.2-1.4-2.21.91.4-1.3-1.3-2.12.31.31.20.9
Liver weight, left9.115.718.14.24.14.14.1-4.14.04.14.1-4.23.84.23.8-4.0-4.24.24.13.8-3.6-4.2-4.00.2
Liver weight, right2.64.65.82.22.22.22.2-2.22.22.22.2-2.32.32.22.3-2.2-2.12.02.02.4-2.1-2.1-2.1-0.2
Locomotor activity1.21.92.8-1.3-1.4-1.4-1.41.5-1.5-1.4-1.41.2-1.5-1.3-1.61.61.3-1.3-1.3-1.51.71.20.90.3
Locomotor testing distance1.94.76.1-2.1-2.3-2.3-2.32.3-2.4-2.3-2.32.0-2.4-2.1-2.42.52.2-2.2-2.1-2.32.51.91.70.5
Locomotor testing rearing1.13.94.8-2.0-2.1-2.0-2.02.1-2.1-2.0-2.02.0-2.2-1.7-2.22.11.9-1.9-1.7-2.02.21.42.01.5
Locomotion in novel chamber1.21.62.51.31.31.31.3-1.31.31.31.3-1.21.21.21.2-1.2-1.31.31.41.2-1.2-1.3-1.6-1.0
Locomotion in novel chamber post-restriction0.00.11.4-0.2-0.2-0.2-0.20.2-0.2-0.2-0.20.2-0.2-0.3-0.20.20.2-0.2-0.1-0.10.20.3-0.0-1.2
Fecal boli incidents, locomotor time 10.92.33.3-1.6-1.6-1.6-1.61.6-1.6-1.6-1.51.7-1.7-1.8-1.71.61.5-1.4-1.2-1.81.21.60.9-1.0
Change in fecal boli incidents, locomotor task0.80.81.20.91.00.90.9-0.91.00.90.9-0.91.10.81.1-1.0-0.80.80.61.0-1.1-0.5-1.0-0.9
Time >=10cm from walls, locomotor time 10.00.00.10.10.20.20.2-0.20.20.20.2-0.20.10.30.2-0.2-0.30.30.30.2-0.1-0.2-0.30.1
Bouts of movement, locomotor time 10.00.00.6-0.10.1-0.0-0.0-0.00.0-0.0-0.00.10.1-0.30.1-0.10.1-0.10.2-0.0-0.10.30.0-0.8
Total resting periods, locomotor time 10.30.31.0-0.6-0.5-0.5-0.50.5-0.5-0.5-0.50.6-0.4-0.8-0.40.40.7-0.7-0.3-0.50.40.80.5-1.0
Rest time, locomotor task time 10.30.52.1-0.7-0.6-0.6-0.60.6-0.6-0.6-0.60.8-0.7-0.9-0.70.60.5-0.5-0.3-0.80.80.80.2-1.4
Distance moved, locomotor task time 10.00.10.50.30.20.20.2-0.20.20.20.1-0.10.40.40.4-0.3-0.10.1-0.20.4-0.1-0.40.10.7
Vertical activity count, locomotor time 10.21.52.31.41.31.21.3-1.21.21.31.3-1.31.11.51.1-1.1-1.41.41.21.2-1.0-1.4-1.3-0.2
Time >=10cm from walls, locomotor time 20.30.91.7-0.9-1.1-1.0-0.91.0-1.0-0.9-0.90.9-1.1-1.1-1.10.80.8-0.8-0.8-1.10.91.10.5-1.3
Bouts of movement, locomotor time 20.93.13.91.82.01.81.8-1.81.81.81.8-1.81.81.81.8-1.7-1.81.81.81.7-1.8-1.6-1.80.1
Total resting periods, locomotor time 20.93.44.31.92.11.91.9-1.91.91.91.9-1.91.91.91.9-1.8-1.91.91.91.8-1.9-1.7-1.80.5
Rest time, locomotor task time 20.00.00.1-0.10.10.00.1-0.00.00.10.10.2-0.10.0-0.10.0-0.20.20.3-0.10.3-0.20.00.4
Distance moved, locomotor task time 20.10.10.6-0.1-0.3-0.2-0.30.2-0.2-0.3-0.30.2-0.0-0.3-0.00.10.4-0.4-0.70.00.10.40.4-0.8
Vertical activity count, locomotor time 20.10.11.20.40.20.20.2-0.10.10.20.2-0.40.00.4-0.00.0-0.30.30.20.10.2-0.5-0.7-1.1
Light reinforcement 11.15.06.2-2.1-2.3-2.4-2.42.4-2.4-2.4-2.42.1-2.2-2.0-2.22.42.5-2.5-2.4-2.22.31.72.21.6
Light reinforcement 20.51.11.4-1.0-1.1-1.1-1.11.1-1.1-1.1-1.21.0-1.1-1.0-1.11.11.2-1.2-1.1-1.01.10.91.00.1
Bone: marrow area6.716.518.84.24.24.34.2-4.24.34.24.2-4.34.34.24.3-4.2-3.93.94.04.3-4.1-4.2-3.50.7
Bone: maximum diameter3.87.612.03.12.82.82.8-2.72.72.82.9-3.02.43.02.4-2.5-3.03.03.12.4-2.1-3.1-3.50.4
Bone: maximum force13.827.331.05.45.55.55.4-5.55.55.45.4-5.55.65.35.6-5.5-5.25.15.15.5-5.5-4.9-4.60.5
Bone: maximum moment15.228.734.05.55.75.65.6-5.65.75.65.5-5.75.85.35.8-5.7-5.25.15.15.7-5.7-4.9-4.70.3
Mean time between licks in bursts0.00.20.8-0.6-0.4-0.4-0.40.4-0.4-0.4-0.50.4-0.2-0.6-0.10.30.6-0.6-0.7-0.00.10.90.6-0.7
Mean num. licks in bursts0.10.21.90.00.10.10.1-0.10.20.10.0-0.10.3-0.40.4-0.20.2-0.2-0.20.3-0.50.6-0.2-1.4
Cd content in liver0.91.02.0-1.1-1.0-0.9-1.00.9-0.9-1.0-0.91.3-0.9-1.1-0.90.81.0-1.0-0.8-0.90.80.81.40.7
Co content in liver0.30.31.0-0.3-0.6-0.5-0.40.5-0.6-0.4-0.40.5-0.9-0.2-1.00.70.1-0.00.0-0.91.0-0.10.30.0
Cu content in liver1.21.42.71.11.11.21.2-1.21.21.21.3-1.20.91.10.9-1.2-1.31.41.60.9-1.1-0.9-0.81.6
Fe content in liver1.82.23.2-1.5-1.6-1.6-1.51.5-1.6-1.5-1.51.4-1.7-1.4-1.71.51.3-1.2-1.3-1.81.51.61.10.2
K content in liver0.10.10.30.2-0.00.00.1-0.10.00.10.2-0.2-0.30.2-0.3-0.1-0.50.50.5-0.50.1-0.3-0.2-0.0
Mg content in liver0.20.21.9-0.2-0.3-0.3-0.30.3-0.4-0.3-0.30.2-0.4-0.4-0.50.40.1-0.1-0.1-0.50.40.4-0.3-1.4
Mn content in liver0.10.11.0-0.0-0.00.0-0.0-0.00.1-0.0-0.10.10.3-0.30.3-0.10.2-0.3-0.40.2-0.40.4-0.1-1.0
Na content in liver0.10.11.2-0.3-0.3-0.3-0.20.2-0.2-0.2-0.10.3-0.5-0.0-0.50.1-0.10.10.1-0.60.3-0.20.71.1
Rb content in liver0.10.10.5-0.2-0.3-0.2-0.10.1-0.2-0.1-0.00.2-0.50.0-0.50.1-0.30.40.3-0.70.30.1-0.10.3
Se content in liver1.51.72.6-1.2-1.5-1.4-1.41.4-1.4-1.3-1.31.2-1.5-1.2-1.51.51.1-1.1-1.2-1.41.61.30.80.8
Sr content in liver1.61.42.61.21.21.21.2-1.21.21.21.2-1.31.01.31.0-1.1-1.21.21.41.1-0.9-1.6-1.01.0
Zn content in liver0.80.91.6-0.9-1.1-1.0-1.01.0-1.1-1.0-1.00.8-1.2-0.9-1.21.10.9-0.9-0.7-1.21.20.70.70.3
Bone: minimum diameter8.917.018.94.44.34.34.3-4.34.34.34.3-4.44.14.34.1-4.2-4.24.24.44.0-3.9-4.3-4.01.2
Time in familiar zone, hab. session 10.20.31.0-0.4-0.4-0.5-0.50.4-0.4-0.5-0.50.4-0.4-0.6-0.40.40.5-0.5-0.5-0.40.30.90.1-1.0
Time in novel zone, hab. session 10.30.41.20.60.60.50.5-0.50.50.50.5-0.60.50.70.5-0.4-0.60.60.50.5-0.3-0.8-0.71.1
Total zone transitions, hab. session 10.30.50.7-0.8-0.7-0.7-0.70.7-0.7-0.7-0.70.6-0.8-0.7-0.80.70.6-0.6-0.6-0.80.60.70.8-0.4
Total locomotion distance, hab. session 10.00.00.20.00.20.20.1-0.10.20.10.1-0.10.3-0.10.3-0.20.1-0.2-0.00.4-0.30.20.1-0.4
Locomotion velocity, hab. session 10.00.10.30.10.30.30.2-0.20.20.20.2-0.30.40.00.4-0.30.0-0.10.10.5-0.40.00.1-0.4
Time in familiar zone, hab. session 20.30.41.20.50.60.60.6-0.60.60.60.6-0.60.70.40.7-0.7-0.50.40.40.6-0.8-0.1-0.6-1.1
Time in novel zone, hab. session 20.30.32.3-0.4-0.5-0.5-0.50.5-0.5-0.5-0.50.4-0.5-0.3-0.50.50.5-0.5-0.4-0.40.6-0.10.71.5
Total zone transitions, hab. session 20.30.40.7-0.7-0.6-0.6-0.60.6-0.6-0.6-0.60.5-0.7-0.7-0.70.50.5-0.5-0.5-0.70.50.90.6-0.6
Total locomotion distance, hab. session 20.10.10.6-0.4-0.2-0.2-0.30.2-0.2-0.3-0.30.2-0.0-0.50.00.20.5-0.5-0.40.2-0.00.70.4-0.8
Locomotion velocity, hab. session 20.10.10.7-0.2-0.0-0.0-0.10.1-0.0-0.1-0.10.10.1-0.40.10.00.3-0.3-0.20.3-0.10.60.2-0.9
Novel to familiar place preference ratio1.41.83.81.41.31.41.4-1.41.41.41.4-1.31.41.71.4-1.4-1.41.41.41.2-1.2-2.0-0.80.6
Novelty place preference1.11.43.11.21.11.21.2-1.21.21.21.2-1.11.21.51.2-1.2-1.21.21.11.0-1.1-1.8-0.70.5
Time in novel zone, NPP test1.01.22.91.11.01.11.1-1.11.11.11.1-1.01.11.41.1-1.1-1.01.01.00.9-1.0-1.7-0.50.8
Total zone transitions, NPP test1.31.92.9-1.5-1.5-1.4-1.41.4-1.4-1.4-1.41.3-1.5-1.5-1.51.31.3-1.3-1.1-1.51.11.71.3-1.3
Total locomotion distance, NPP test1.52.13.3-1.6-1.4-1.4-1.51.5-1.4-1.5-1.51.4-1.3-1.7-1.21.41.7-1.7-1.5-1.11.11.81.6-0.7
Locomotion velocity, NPP test0.81.22.1-1.2-1.1-1.0-1.11.1-1.0-1.1-1.11.0-1.0-1.3-0.91.11.2-1.2-1.0-0.70.81.41.1-0.9
Intraocular pressure5.79.411.0-3.1-3.1-3.1-3.23.2-3.2-3.2-3.23.0-3.0-3.3-3.03.33.3-3.3-3.3-2.73.13.22.6-1.6
Delta distance traveled before/after self-admin0.10.11.50.10.10.10.1-0.10.10.10.1-0.10.1-0.00.1-0.1-0.00.0-0.00.10.00.2-0.4-1.2
Delta ambulatory time before/after self-admin0.00.00.2-0.1-0.1-0.2-0.20.2-0.2-0.2-0.20.2-0.2-0.1-0.30.20.1-0.1-0.2-0.20.50.2-0.2-0.5
Parametrial fat weight1.02.23.4-1.4-1.6-1.6-1.51.6-1.6-1.5-1.51.5-1.8-1.3-1.81.81.3-1.3-1.3-1.81.81.40.9-0.6
Pavlov. Cond. lever latency0.20.31.20.20.50.40.4-0.50.60.40.3-0.21.00.11.0-0.70.1-0.1-0.20.9-1.10.10.2-0.3
Pavlov. Cond. magazine entry latency0.10.11.5-0.1-0.2-0.2-0.20.2-0.2-0.2-0.2-0.0-0.1-0.1-0.10.20.2-0.2-0.2-0.10.20.10.31.2
Pavlov. Cond. change in total contacts0.20.23.30.2-0.00.00.1-0.0-0.00.10.1-0.2-0.30.4-0.30.1-0.40.40.4-0.20.4-0.5-0.21.8
Pavlov. Cond. index score0.10.21.60.2-0.10.00.10.0-0.10.10.1-0.2-0.40.4-0.40.2-0.40.40.5-0.30.5-0.6-0.21.3
Pavlov. Cond. latency score0.10.21.00.2-0.1-0.00.00.1-0.10.00.1-0.2-0.50.3-0.50.3-0.40.40.5-0.40.6-0.5-0.31.0
Pavlov. Cond. lever contacts0.60.71.8-0.6-0.9-0.8-0.70.8-0.9-0.7-0.70.7-1.3-0.4-1.31.00.3-0.3-0.2-1.31.30.10.51.0
Pavlov. Cond. magazine entry number0.10.11.70.00.10.10.1-0.10.10.10.10.00.2-0.10.3-0.20.0-0.0-0.10.2-0.30.2-0.1-1.3
Pavlov. Cond. intertrial magazine entries0.40.51.9-0.7-0.6-0.6-0.60.6-0.6-0.6-0.60.8-0.6-1.0-0.50.50.7-0.7-0.6-0.70.31.30.3-1.4
Pavlov. Cond. lever-magazine prob. diff.0.20.21.30.40.20.20.3-0.20.20.30.4-0.4-0.20.6-0.2-0.1-0.60.70.8-0.20.2-0.8-0.41.1
Pavlov. Cond. response bias0.20.21.4-0.3-0.5-0.4-0.40.5-0.5-0.4-0.40.3-0.6-0.3-0.60.50.3-0.3-0.2-0.60.60.10.41.2
Pavlov. Cond. lever latency0.10.10.40.30.30.30.3-0.30.40.30.3-0.40.40.20.4-0.5-0.20.20.20.4-0.5-0.1-0.1-0.6
Pavlov. Cond. magazine entry latency1.01.41.61.31.21.21.2-1.21.21.21.2-1.21.21.21.2-1.1-1.11.11.11.1-1.1-1.2-1.11.2
Pavlov. Cond. change in total contacts0.92.23.81.61.41.51.6-1.51.51.61.6-1.31.21.71.1-1.4-1.81.81.91.0-1.1-2.0-1.60.6
Pavlov. Cond. index score0.60.91.61.00.90.91.0-0.90.91.01.0-0.80.81.00.8-0.9-1.01.11.10.7-0.7-1.2-0.91.3
Pavlov. Cond. latency score0.50.81.10.90.80.90.9-0.90.80.90.9-0.80.71.00.7-0.8-1.01.01.00.7-0.7-1.0-1.00.9
Pavlov. Cond. lever contacts0.00.10.4-0.1-0.1-0.2-0.10.2-0.2-0.1-0.10.2-0.3-0.1-0.30.30.0-0.0-0.0-0.20.4-0.1-0.10.7
Pavlov. Cond. magazine entry number2.33.03.7-1.8-1.8-1.8-1.81.8-1.7-1.8-1.81.7-1.6-1.9-1.61.71.8-1.8-1.9-1.61.61.91.6-1.6
Pavlov. Cond. intertrial magazine entries3.88.49.8-2.9-3.0-3.0-3.03.0-3.0-3.0-3.02.9-2.9-3.1-2.93.02.9-2.9-3.0-2.92.93.12.2-2.0
Pavlov. Cond. lever-magazine prob. diff.0.81.21.81.21.11.11.1-1.11.11.11.2-1.00.91.20.9-1.0-1.21.21.20.9-0.9-1.3-1.11.3
Pavlov. Cond. response bias0.10.11.40.30.30.20.3-0.30.20.30.3-0.20.20.40.1-0.2-0.30.40.30.1-0.1-0.5-0.31.2
Time in closed arm before self-admin1.73.03.91.71.71.81.7-1.71.71.71.8-1.81.62.01.6-1.6-1.81.71.91.7-1.7-2.0-1.21.5
Time in closed arm after self-admin0.20.20.30.40.40.40.4-0.40.40.40.4-0.50.50.50.5-0.3-0.30.20.30.5-0.4-0.4-0.20.6
Time in open arm before self-admin0.20.23.6-0.1-0.1-0.2-0.20.2-0.2-0.2-0.20.3-0.0-0.2-0.10.10.2-0.2-0.4-0.00.30.00.41.9
Time in open arm after self-admin0.10.11.7-0.2-0.2-0.2-0.20.2-0.2-0.2-0.20.3-0.2-0.4-0.2-0.00.2-0.2-0.2-0.30.10.10.2-1.3
Bone: periosteal estimation11.326.831.05.55.45.45.4-5.35.35.45.4-5.65.25.45.1-5.1-5.35.35.45.1-4.8-5.3-5.30.5
Bone: periosteal perimeter9.518.721.94.74.54.54.5-4.44.44.54.5-4.64.34.54.2-4.3-4.54.44.64.1-4.0-4.4-4.70.6
Bone: post-yield work7.412.814.93.73.83.73.7-3.73.73.73.7-3.83.93.83.8-3.8-3.53.43.43.7-3.7-3.6-3.11.0
Progressive ratio test 1 active lever presses3.96.89.0-2.6-2.8-2.8-2.72.8-2.8-2.7-2.72.6-3.0-2.4-3.02.72.4-2.4-2.2-2.93.02.02.51.0
Progressive ratio test 1 breakpoint3.66.38.5-2.5-2.7-2.6-2.62.6-2.7-2.6-2.52.5-2.9-2.2-2.92.62.3-2.3-2.1-2.92.91.82.41.0
Progressive ratio test 1 inactive lever presses1.12.94.5-1.7-1.9-1.9-1.81.8-1.9-1.8-1.71.6-2.0-1.5-2.02.01.5-1.5-1.5-2.12.01.31.40.2
Progressive ratio test 2 active lever presses1.72.43.7-1.5-1.5-1.6-1.61.6-1.7-1.6-1.61.7-1.8-1.3-1.81.71.4-1.3-1.2-1.61.91.01.61.0
Progressive ratio test 2 breakpoint1.82.23.5-1.5-1.5-1.5-1.51.6-1.6-1.5-1.51.6-1.8-1.3-1.81.61.3-1.3-1.2-1.61.90.91.61.1
Progressive ratio test 2 inactive lever presses0.62.03.0-1.3-1.3-1.5-1.41.5-1.5-1.4-1.41.5-1.7-1.2-1.71.61.2-1.2-1.2-1.61.71.01.21.1
Incentive Sensitization - Responses0.10.20.70.60.70.40.4-0.40.30.40.4-0.40.20.60.2-0.2-0.60.60.60.5-0.0-0.5-0.80.3
Incentive Sensitization - Breakpoint0.10.10.40.50.60.30.3-0.20.20.30.3-0.30.10.40.1-0.1-0.40.40.50.40.1-0.4-0.60.4
Sum of active levers in priming session hrs 5-60.10.10.6-0.00.10.10.1-0.20.20.10.10.00.30.00.3-0.40.0-0.00.00.1-0.5-0.10.40.8
Progressive ratio0.10.20.5-0.4-0.5-0.5-0.50.6-0.6-0.5-0.50.4-0.5-0.4-0.60.70.5-0.5-0.5-0.40.70.40.00.3
Food seeking constrained by brief footshock0.91.12.3-1.0-1.1-1.0-1.01.1-1.1-1.0-1.01.0-1.2-0.8-1.21.10.8-0.8-0.7-1.21.10.80.91.5
Seeking ratio, punishment vs. effort0.00.00.2-0.2-0.2-0.2-0.10.1-0.1-0.1-0.10.2-0.2-0.2-0.2-0.00.1-0.10.0-0.30.10.20.50.3
Retroperitoneal fat weight0.31.55.4-1.0-1.2-1.2-1.11.1-1.2-1.1-1.11.2-1.1-1.4-1.11.21.1-1.1-1.2-1.21.01.60.3-2.3
Reaction time number correct0.62.14.01.51.61.61.4-1.51.51.41.4-1.61.81.11.8-1.5-1.11.01.12.0-1.9-0.9-1.60.5
Reaction time mean minus median1.710.712.3-3.5-3.4-3.4-3.43.4-3.4-3.4-3.43.4-3.4-3.3-3.43.53.2-3.2-3.2-3.43.33.23.00.1
Reaction time mean minus median AUC1.17.58.8-3.0-2.8-2.8-2.82.8-2.8-2.8-2.82.9-2.8-2.8-2.72.92.8-2.8-2.8-2.72.72.72.71.1
Reaction time num false alarms1.11.92.6-1.4-1.4-1.4-1.41.4-1.4-1.4-1.51.4-1.3-1.5-1.31.41.5-1.5-1.6-1.21.41.51.1-0.5
Reaction time num false alarms AUC1.22.83.9-1.8-1.7-1.7-1.81.7-1.7-1.7-1.81.8-1.6-1.8-1.61.71.8-1.8-2.0-1.41.71.81.6-0.2
Reaction time trials correct on left0.62.14.01.51.61.61.4-1.51.51.41.4-1.61.81.11.8-1.5-1.11.01.12.0-1.9-0.9-1.60.5
Reaction time trials on left0.51.73.41.31.41.41.2-1.31.41.21.2-1.41.60.91.7-1.3-0.90.80.91.8-1.7-0.7-1.40.5
Reaction time mean0.41.01.5-1.1-1.0-1.0-1.01.0-1.1-1.0-1.01.1-1.2-0.9-1.21.10.8-0.7-0.8-1.11.10.80.8-0.2
Reaction time mean AUC0.20.50.9-0.8-0.7-0.8-0.70.8-0.8-0.7-0.70.8-1.0-0.7-1.00.80.5-0.5-0.5-0.90.90.60.5-0.2
Median of all reaction times0.00.00.10.00.10.00.1-0.00.00.10.1-0.0-0.20.2-0.20.0-0.30.30.3-0.10.1-0.3-0.1-0.2
Reaction time omissions8.413.615.9-3.8-3.8-3.8-3.93.8-3.8-3.9-3.93.9-3.7-4.0-3.73.93.9-3.9-3.8-3.63.53.93.0-1.2
Reaction time false alarm rate2.43.34.3-1.9-1.9-1.9-1.91.9-1.9-1.9-1.92.0-1.9-1.8-1.91.91.7-1.7-1.9-1.92.11.71.8-0.6
Reaction time premature initiation rate4.87.410.3-2.7-2.9-2.9-2.82.9-3.0-2.8-2.82.7-3.2-2.5-3.23.12.5-2.4-2.4-3.23.12.22.2-0.1
Reaction time premature initiations1.13.34.7-1.8-1.9-2.0-1.92.0-2.0-1.9-1.91.8-2.0-1.8-2.02.21.8-1.8-1.7-1.91.91.71.20.3
Std. dev. reaction times2.58.59.6-3.1-3.0-3.0-3.03.0-3.0-3.0-3.03.1-3.1-3.0-3.13.12.9-2.8-2.9-3.02.92.92.6-0.1
Reaction time trials completed0.51.73.41.31.41.41.2-1.31.41.21.2-1.41.60.91.7-1.3-0.90.80.91.8-1.7-0.7-1.40.5
Reaction time trials AUC0.82.74.81.71.81.71.6-1.71.71.61.6-1.72.01.22.1-1.7-1.21.11.32.2-2.1-1.0-1.70.3
Run reversals in cocaine runway, females0.00.00.10.20.10.10.1-0.20.20.10.1-0.10.30.20.3-0.3-0.00.0-0.20.1-0.2-0.2-0.00.3
Run reversals in cocaine runway, males1.11.21.4-1.1-1.1-1.1-1.11.1-1.1-1.1-1.11.0-1.1-1.1-1.11.11.1-1.1-1.2-1.21.11.10.8-0.5
Latency to leave start box in cocaine runway0.00.00.3-0.1-0.1-0.2-0.20.2-0.2-0.2-0.20.1-0.2-0.0-0.20.20.1-0.1-0.1-0.20.20.1-0.0-0.6
Latency to leave start box in cocaine runway, F0.81.11.3-1.0-1.0-1.1-1.11.1-1.1-1.1-1.11.0-1.1-0.9-1.11.21.1-1.1-1.0-1.01.10.91.00.2
Latency to leave start box in cocaine runway, M1.71.72.21.31.31.31.3-1.31.31.31.3-1.31.21.31.2-1.3-1.41.41.21.1-1.2-1.2-1.5-1.3
Std. dev. time between licks in bursts0.61.12.0-1.1-1.0-1.1-1.11.1-1.2-1.1-1.11.0-1.2-0.9-1.21.30.9-0.9-1.0-1.01.40.90.80.1
Total sessions with >9 infusions2.22.75.3-1.5-1.7-1.7-1.71.8-1.9-1.7-1.61.5-2.2-1.3-2.22.01.3-1.3-1.1-2.02.31.20.90.5
Short access day 1 total inactive lever presses1.22.43.7-1.5-1.7-1.6-1.61.6-1.7-1.6-1.51.5-1.9-1.4-1.91.61.3-1.3-1.2-1.91.91.11.51.2
Short access day 10 total inactive lever presses0.00.21.0-0.5-0.4-0.4-0.40.3-0.3-0.4-0.40.5-0.2-0.5-0.20.30.5-0.5-0.5-0.40.00.41.00.5
Short access day 1 total infusions0.50.92.0-0.9-1.0-1.0-0.91.0-1.1-0.9-0.90.8-1.3-0.8-1.31.20.7-0.6-0.5-1.21.40.60.40.2
Short access day 10 total infusions1.22.03.9-1.3-1.6-1.5-1.41.5-1.6-1.4-1.41.2-1.9-1.1-2.01.51.0-1.0-0.9-2.01.90.90.90.4
Short access total infusions2.23.26.0-1.6-1.9-1.9-1.81.9-2.0-1.8-1.81.6-2.3-1.4-2.42.11.4-1.4-1.3-2.22.51.21.10.7
Short access day 1 locomotion0.20.30.7-0.5-0.6-0.5-0.50.5-0.6-0.5-0.40.4-0.8-0.2-0.80.70.2-0.2-0.1-0.80.8-0.00.40.3
Short access day 10 total locomotion0.10.30.6-0.6-0.7-0.6-0.60.6-0.6-0.6-0.60.5-0.6-0.5-0.60.50.6-0.6-0.6-0.80.50.20.70.6
Short access total locomotion0.71.11.9-1.0-1.2-1.1-1.11.1-1.1-1.1-1.01.0-1.3-0.8-1.31.10.9-0.9-0.8-1.41.20.51.00.8
One hour access (0.3 mA shock)0.30.31.9-0.3-0.5-0.5-0.40.5-0.5-0.4-0.40.3-0.8-0.1-0.80.60.1-0.1-0.1-0.71.0-0.00.01.4
Compulsive drug intake0.30.47.6-0.0-0.0-0.0-0.00.0-0.0-0.0-0.0-0.00.1-0.20.1-0.10.1-0.2-0.1-0.0-0.10.2-0.3-2.8
One hour access (shock baseline)0.20.58.10.1-0.0-0.1-0.10.1-0.2-0.1-0.0-0.0-0.40.3-0.50.4-0.30.30.3-0.30.6-0.3-0.22.8
Social response proportion0.20.20.7-0.4-0.4-0.4-0.40.4-0.5-0.4-0.40.5-0.6-0.3-0.60.60.2-0.2-0.2-0.60.80.10.2-0.3
Social responses7.19.312.0-3.2-3.2-3.2-3.23.2-3.2-3.1-3.13.2-3.3-2.9-3.33.32.9-2.8-3.0-3.33.52.52.70.8
Social time0.00.00.80.00.00.00.1-0.10.10.10.1-0.00.1-0.10.1-0.1-0.00.00.2-0.1-0.20.0-0.1-0.9
Soleus weight0.51.52.11.31.21.31.3-1.31.31.31.3-1.21.31.31.2-1.5-1.31.31.31.0-1.3-1.4-0.70.2
Bone: stiffness15.928.932.65.65.75.65.6-5.65.65.65.6-5.75.65.65.6-5.5-5.45.45.45.6-5.3-5.3-4.91.3
Tibialis anterior weight0.82.88.01.61.31.51.7-1.61.51.71.8-1.40.92.20.9-1.5-2.22.32.40.5-1.0-2.8-0.91.6
Time to tail flick, vehicle, before self-admin1.31.62.4-1.3-1.2-1.3-1.31.3-1.2-1.3-1.31.4-1.0-1.5-1.01.31.4-1.5-1.4-1.01.21.51.1-1.1
Time to tail flick, vehicle, after self-admin0.10.10.90.20.30.30.3-0.30.30.30.3-0.40.30.30.3-0.4-0.20.20.30.4-0.5-0.50.20.9
Time to tail flick, test, before self-admin0.30.41.5-0.5-0.5-0.5-0.50.5-0.4-0.5-0.50.5-0.3-0.8-0.30.20.6-0.7-0.8-0.4-0.01.10.6-1.2
Time to tail flick, test, after self-admin0.70.71.10.90.90.90.9-0.90.90.80.8-0.90.90.90.9-0.9-0.80.80.81.0-1.0-0.6-0.70.4
Delta time to tail flick, vehicle, before/after SA0.50.50.80.60.60.70.7-0.70.70.70.7-0.80.50.80.5-0.7-0.70.80.90.5-0.8-0.9-0.40.8
Delta time to tail flick, test, before/after SA0.30.30.60.60.50.50.5-0.50.50.50.5-0.60.40.70.4-0.2-0.60.60.70.5-0.3-0.8-0.70.6
Tibia length7.119.924.44.64.64.64.7-4.64.64.74.7-4.74.24.84.2-4.5-4.94.94.84.2-4.0-4.7-4.3-0.8
Ambulatory time before self-admin0.82.53.5-1.8-1.7-1.6-1.61.6-1.6-1.6-1.61.7-1.6-1.7-1.61.61.7-1.7-1.5-1.61.31.51.90.3
Ambulatory time after self-admin0.81.31.6-1.1-1.2-1.2-1.21.2-1.2-1.2-1.21.2-1.3-1.2-1.31.21.1-1.1-1.0-1.11.31.11.0-0.6
Bone: tissue strength1.01.12.30.91.11.11.1-1.11.21.11.0-0.91.40.91.4-1.4-0.80.80.71.2-1.5-0.7-0.3-0.0
Total heroin consumption0.91.01.71.00.91.01.0-1.01.01.01.0-0.91.01.11.0-1.2-1.01.00.80.9-1.1-1.3-0.41.3
Bone: trabecular number5.410.212.53.43.43.33.3-3.33.33.33.3-3.33.43.13.4-3.2-3.13.13.03.5-3.3-2.7-3.4-0.8
Bone: trabecular spacing2.13.14.1-1.8-1.8-1.9-1.81.9-1.9-1.8-1.81.7-2.0-1.7-2.01.91.6-1.6-1.6-2.01.91.41.5-0.2
Bone: trabecular thickness0.00.10.1-0.2-0.2-0.2-0.30.3-0.3-0.3-0.20.3-0.3-0.3-0.30.30.3-0.3-0.2-0.20.40.10.1-0.0
Bone: trabecular tissue density0.00.00.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.10.00.1-0.10.10.00.2-0.2-0.30.20.10.20.10.1
Water consumed over 24 hours0.10.10.20.40.40.40.3-0.30.40.30.3-0.40.50.30.5-0.4-0.20.20.20.5-0.4-0.2-0.40.1
Number of responses in last shaping day0.40.68.5-0.3-0.3-0.3-0.30.4-0.4-0.3-0.30.4-0.60.0-0.60.40.1-0.10.1-0.40.7-0.50.82.9