Tuba1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr7_131993996_131995751 0.05 0.04 3.5e-05 0.04 0.04 0.04 0.04 1.8e-05 3.5e-05 1.1e-05 2.5e-05
2 Brain gene expression Tuba1b 0.79 0.11 0.0e+00 0.52 0.52 0.52 0.53 5.5e-57 4.2e-56 1.5e-56 4.7e-57
3 IL gene expression Tuba1b 0.87 0.09 0.0e+00 0.4 0.5 0.46 0.5 1.2e-10 5.4e-14 1.1e-12 6.8e-14
4 BLA intron excision ratio chr7_131971419_131972486 0.17 0.14 1.4e-07 0.12 0.13 0.13 0.13 3.7e-07 1.6e-07 2.5e-07 2.4e-07
5 Brain intron excision ratio chr7_131993996_131995751 0.13 0.08 1.3e-14 0.14 0.15 0.14 0.14 4.7e-13 3.8e-14 4.0e-13 3.4e-13
6 Eye gene expression Tuba1b 0.3 0.29 3.4e-03 0.14 0.17 0.14 0.15 3.2e-03 1.3e-03 3.4e-03 2.9e-03
7 Brain intron excision ratio chr7_131971419_131972486 0.1 0.07 2.2e-10 0.09 0.11 0.1 0.1 5.8e-09 2.8e-10 5.3e-10 1.3e-09
8 BLA gene expression Tuba1b 0.21 0.15 3.3e-10 0.15 0.18 0.16 0.16 3.7e-08 7.6e-10 1.0e-08 1.3e-08
9 OFC gene expression Tuba1b 0.75 0.13 0.0e+00 0.47 0.46 0.47 0.46 8.3e-13 2.1e-12 1.5e-12 2.0e-12
10 LHb gene expression Tuba1b 0.82 0.12 0.0e+00 0.47 0.5 0.47 0.48 1.1e-12 9.6e-14 8.3e-13 5.0e-13
11 BLA intron excision ratio chr7_131993996_131995751 0.09 0.09 1.6e-04 0.08 0.07 0.08 0.07 6.6e-05 1.4e-04 4.8e-05 1.2e-04
12 PL gene expression Tuba1b 0.48 0.18 0.0e+00 0.28 0.28 0.27 0.28 2.0e-30 1.1e-30 1.0e-29 2.5e-30
13 Liver gene expression Tuba1b 0.46 0.19 0.0e+00 0.42 0.42 0.42 0.42 1.5e-50 1.1e-49 4.5e-50 2.4e-50
14 IC intron excision ratio chr7_131971419_131972486 0.21 0.24 1.7e-05 0.11 0.11 0.12 0.12 2.3e-05 1.8e-05 1.1e-05 1.3e-05
15 IC intron excision ratio chr7_131993996_131995751 0.16 0.16 4.9e-05 0.1 0.1 0.11 0.1 5.1e-05 4.7e-05 2.7e-05 3.7e-05
16 RMTg gene expression Tuba1b 0.55 0.25 9.6e-12 0.3 0.36 0.33 0.36 9.5e-09 2.2e-10 1.4e-09 1.4e-10
17 NAcc gene expression Tuba1b 0.63 0.13 0.0e+00 0.18 0.18 0.18 0.18 5.2e-27 3.0e-27 6.8e-27 6.3e-27
18 IC gene expression Tuba1b 0.6 0.27 0.0e+00 0.37 0.37 0.38 0.37 2.7e-16 2.7e-16 4.5e-17 1.2e-16
19 pVTA gene expression Tuba1b 0.04 0.04 2.3e-03 0.02 0.01 0.01 0.01 8.1e-03 2.7e-02 8.9e-02 2.1e-02
20 PL intron excision ratio chr7_131971419_131972486 0.06 0.05 5.7e-06 0.05 0.05 0.05 0.05 5.9e-06 6.0e-06 4.5e-06 7.2e-06
21 Adipose gene expression Tuba1b 0.04 0.04 7.4e-05 0.03 0.03 0.04 0.03 1.0e-04 3.5e-04 7.7e-05 2.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density9.416.218.2-4.24.24.24.2-4.24.24.24.24.24.1-4.14.14.04.1-4.14.04.33.93.94.0-0.0
Area under the delay curve0.60.71.2-0.80.80.90.9-0.90.90.90.91.00.7-1.00.70.81.1-1.11.00.60.60.80.90.3
BMI with tail6.422.127.0-4.94.74.84.9-4.94.85.04.94.84.6-5.14.54.65.2-5.24.94.34.34.94.8-0.4
BMI without tail1.75.17.8-2.42.22.22.4-2.32.22.42.42.21.9-2.51.92.02.6-2.72.51.71.72.82.81.1
Body weight6.428.034.6-5.55.45.45.6-5.55.45.65.65.45.0-5.74.95.15.9-5.95.74.74.85.75.51.1
Weight adjusted by age2.23.44.2-1.91.91.91.9-1.91.91.92.01.91.7-2.01.71.92.0-2.02.11.71.62.11.5-1.1
Bone surface11.320.724.1-4.94.84.74.7-4.74.74.74.74.84.7-4.64.64.54.6-4.54.54.74.44.44.90.3
Bone volume8.815.819.9-4.34.24.14.1-4.14.14.14.14.24.1-4.04.13.94.0-3.93.94.23.83.74.50.5
Breakpoint value in progressive ratio session1.31.52.2-1.21.21.31.3-1.31.31.31.31.21.3-1.21.31.51.2-1.21.31.01.41.30.5-0.5
Number of licking bursts0.30.51.30.6-0.8-0.7-0.60.7-0.8-0.6-0.6-0.8-1.00.3-1.0-0.8-0.30.2-0.3-1.0-1.1-0.0-0.4-0.5
Context. condit. distance diff. score0.30.41.8-0.50.50.50.6-0.50.50.50.60.50.4-0.80.30.60.7-0.70.70.30.41.0-0.0-1.3
Locomotion velocity, session 10.90.91.81.0-0.9-1.0-1.01.0-0.9-1.0-1.0-0.8-0.81.1-0.8-0.9-1.01.0-1.1-0.9-0.7-1.3-0.81.3
Locomotion distance, session 12.73.45.62.1-1.9-1.8-1.91.8-1.8-1.9-1.9-1.8-1.62.1-1.6-1.6-2.12.1-2.0-1.6-1.3-2.3-2.40.8
Locomotion velocity, session 20.40.55.10.6-0.5-0.5-0.50.5-0.5-0.5-0.5-0.4-0.40.8-0.4-0.5-0.50.5-0.6-0.3-0.3-1.0-0.32.3
Locomotion distance, session 22.23.15.51.9-1.7-1.7-1.81.8-1.7-1.8-1.8-1.6-1.62.1-1.5-1.6-1.91.9-1.8-1.4-1.4-2.3-1.81.4
Locomotion velocity, session 33.84.46.02.2-2.1-2.1-2.22.2-2.2-2.2-2.2-2.1-2.12.3-2.1-2.1-2.12.1-2.1-2.0-2.0-2.5-1.70.9
Locomotion distance, session 34.75.16.62.4-2.3-2.3-2.42.4-2.3-2.4-2.4-2.2-2.22.4-2.1-2.3-2.52.5-2.3-1.8-2.2-2.6-1.90.4
Stereotopy head waving bouts, day 31.51.85.1-1.41.31.31.2-1.21.21.31.21.41.3-1.11.21.01.2-1.21.21.51.10.72.32.1
Stereotopy head waving duration, day 31.11.36.7-1.11.01.00.9-0.90.90.90.91.01.0-0.61.00.80.8-0.80.71.10.90.32.02.6
Locomotion velocity, session 70.20.20.50.4-0.3-0.4-0.50.5-0.5-0.5-0.5-0.3-0.50.2-0.5-0.6-0.50.5-0.3-0.2-0.7-0.0-0.4-0.4
Locomotion distance, session 71.41.82.81.3-1.3-1.3-1.41.5-1.4-1.4-1.4-1.2-1.51.0-1.4-1.6-1.41.4-1.2-1.1-1.7-0.7-1.4-1.5
Stereotopy head waving bouts, day 71.51.74.4-1.51.31.31.3-1.21.21.31.31.31.1-1.31.11.11.3-1.31.31.21.01.32.11.5
Stereotopy head waving duration, day 71.21.53.4-1.31.11.11.2-1.21.11.21.21.21.1-1.11.11.11.2-1.21.11.01.11.11.91.5
Locomotion velocity, session 80.10.11.80.1-0.1-0.00.0-0.00.00.00.1-0.1-0.10.0-0.10.10.2-0.20.1-0.30.1-0.1-0.31.3
Locomotion distance, session 81.11.64.11.5-1.2-1.3-1.31.3-1.3-1.3-1.3-1.3-1.31.2-1.2-1.1-1.31.3-1.3-1.2-1.1-1.3-2.0-0.1
Degree of sensitization distance0.60.61.8-0.80.70.70.7-0.70.70.70.70.70.5-1.00.50.60.8-0.80.80.60.41.30.5-0.8
Degree of sensitization stereotypy0.20.20.9-0.50.30.30.4-0.30.30.40.40.40.2-0.50.10.20.6-0.60.50.10.10.71.00.6
Conditioned locomotion0.00.00.2-0.20.20.20.1-0.10.10.10.10.30.2-0.10.20.20.1-0.10.10.50.1-0.20.4-0.1
Cocaine response after cond. corrected0.10.11.30.2-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.10.2-0.1-0.1-0.10.0-0.1-0.1-0.1-0.30.01.1
Cocaine response after cond. not corrected0.60.71.00.9-0.8-0.9-0.90.8-0.8-0.8-0.9-0.9-0.80.9-0.8-0.9-0.80.8-0.9-0.8-0.7-1.0-0.61.0
Cocaine response before conditioning3.44.15.32.0-2.0-2.1-2.12.1-2.1-2.1-2.2-2.1-1.92.0-1.9-2.0-2.22.2-2.3-1.9-1.9-1.9-1.9-0.3
Saline control response0.00.00.1-0.20.30.20.2-0.20.20.20.10.20.3-0.20.30.20.1-0.00.00.20.30.10.2-0.0
Bone: connectivity density6.610.211.6-3.43.43.33.3-3.33.33.33.33.33.3-3.23.33.23.2-3.23.13.43.23.03.40.1
Bone: cortical apparent density0.20.20.50.6-0.4-0.4-0.50.5-0.4-0.5-0.5-0.6-0.30.5-0.3-0.4-0.60.6-0.7-0.1-0.4-0.4-0.7-0.6
Bone: cortical area10.916.821.5-4.44.34.24.3-4.24.14.34.34.43.9-4.33.94.04.4-4.44.43.83.64.24.6-0.3
Bone: cortical porosity0.70.81.70.8-0.8-0.8-0.90.9-0.8-0.9-1.0-0.7-0.41.1-0.4-0.7-1.31.3-1.2-0.4-0.4-1.3-0.7-0.9
Bone: cortical porosity1.01.12.80.9-0.9-0.9-1.11.0-0.9-1.1-1.1-0.8-0.61.2-0.6-0.9-1.41.5-1.3-0.4-0.6-1.3-0.8-1.7
Bone: cortical thickness4.27.012.1-2.92.72.62.8-2.72.62.72.82.82.2-2.82.22.43.1-3.13.12.12.12.73.50.1
Bone: cortical thickness0.20.20.6-0.50.40.40.4-0.30.30.40.40.60.0-0.70.00.10.6-0.60.80.2-0.10.80.6-0.4
Bone: cortical tissue density0.30.30.70.7-0.5-0.5-0.60.6-0.5-0.6-0.6-0.7-0.40.6-0.3-0.5-0.70.7-0.8-0.2-0.5-0.5-0.8-0.5
Condit. Reinf. active minus inactive responses0.10.10.60.1-0.2-0.2-0.20.2-0.2-0.2-0.2-0.0-0.10.5-0.1-0.2-0.40.4-0.2-0.1-0.1-0.60.10.7
Condit. Reinf. active-inactive response ratio0.30.30.8-0.50.60.60.5-0.50.60.50.50.70.8-0.20.80.60.2-0.20.40.90.80.10.30.1
Condit. Reinf. active responses0.60.71.50.8-0.8-0.8-0.80.8-0.8-0.8-0.8-0.7-0.91.1-0.9-0.8-0.80.8-0.7-0.9-0.8-1.2-0.31.1
Condit. Reinf. inactive responses2.73.34.51.8-2.0-1.9-1.91.9-1.9-1.9-1.8-1.9-2.11.8-2.1-1.9-1.61.6-1.7-2.1-1.9-1.8-1.40.4
Incentive salience index mean0.00.00.3-0.10.10.20.1-0.10.10.10.20.20.00.00.00.10.2-0.20.30.10.1-0.10.20.5
Condit. Reinf. lever presses0.10.10.5-0.30.30.40.4-0.30.30.40.40.30.1-0.20.10.30.5-0.60.70.10.20.20.30.5
Condit. Reinf. active minus inactive responses0.00.00.10.1-0.1-0.1-0.10.1-0.1-0.1-0.2-0.1-0.00.1-0.0-0.2-0.30.3-0.2-0.0-0.00.00.1-0.2
Condit. Reinf. active-inactive response ratio0.30.40.70.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.60.6-0.6-0.7-0.60.6-0.5-0.8-0.5-0.6-0.00.9
Condit. Reinf. active responses0.20.31.50.4-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.40.4-0.4-0.6-0.70.7-0.6-0.3-0.5-0.2-0.4-1.2
Condit. Reinf. inactive responses0.60.83.10.7-0.8-0.8-0.80.8-0.8-0.8-0.9-0.8-0.70.6-0.7-0.8-0.91.0-1.0-0.6-0.8-0.4-1.0-1.8
Condit. Reinf. lever presses0.10.23.5-0.10.10.10.1-0.10.10.10.10.00.2-0.20.20.00.0-0.00.10.30.00.5-0.1-1.9
Condit. Reinf. lever reinforcers received0.50.72.50.8-0.8-0.8-0.80.8-0.8-0.8-0.9-0.8-0.70.7-0.7-0.9-1.01.0-0.9-0.7-0.7-0.4-0.8-1.6
Conditioned reinforcement - actives1.01.72.81.2-1.3-1.4-1.31.4-1.4-1.3-1.3-1.3-1.61.2-1.6-1.7-1.11.1-1.1-1.6-1.6-1.1-0.20.6
Conditioned reinforcement - inactives3.75.47.32.2-2.4-2.5-2.42.5-2.5-2.4-2.4-2.2-2.72.3-2.7-2.7-2.22.2-2.1-2.7-2.7-2.2-1.10.9
Conditioned locomotion0.20.20.40.4-0.4-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.4-0.6-0.6-0.40.4-0.5-0.6-0.6-0.2-0.10.0
Patch foraging indifference point 0 sec1.93.54.61.8-1.9-2.0-1.91.9-2.0-1.9-1.9-1.9-2.01.8-2.1-2.0-1.91.8-1.8-2.1-2.1-1.6-1.4-0.2
Patch foraging indifference point AUC0.71.01.70.9-1.0-1.1-1.01.1-1.1-1.0-1.1-0.9-1.10.8-1.1-1.1-0.90.9-1.2-1.0-1.3-0.9-0.60.8
Delay disc. indifference point, 0s delay1.21.31.9-1.21.11.11.1-1.11.11.11.11.31.1-1.11.01.11.2-1.21.01.01.00.81.41.1
Delay disc. indifference point, 16s delay0.70.81.2-0.80.80.90.9-0.90.90.90.90.90.7-1.00.70.81.0-1.11.10.50.61.01.0-0.5
Delay disc. indifference point, 2s delay1.11.21.5-1.01.11.21.2-1.21.21.21.21.11.2-1.11.21.21.1-1.11.11.21.20.90.80.4
Delay disc. indifference point, 24s delay0.91.11.6-0.91.11.01.1-1.11.01.11.11.10.9-1.20.91.11.2-1.21.20.80.81.10.7-0.3
Delay disc. indifference point, 4s delay0.30.30.5-0.40.50.60.6-0.60.60.60.60.40.5-0.50.60.60.6-0.60.50.50.50.50.20.7
Delay disc. indifference point, 8s delay1.82.13.0-1.51.31.51.5-1.51.41.51.51.61.2-1.71.21.41.7-1.71.71.11.11.41.60.3
Indifference point function ln k2.95.05.8-2.32.32.32.3-2.32.32.32.32.32.3-2.22.32.32.2-2.12.42.32.42.22.2-1.0
Indifference point function log k2.95.05.8-2.32.32.32.3-2.32.32.32.32.32.3-2.22.32.32.2-2.12.42.32.42.22.2-1.0
Patch foraging total patch changes 0 sec1.83.44.41.8-1.9-2.0-1.91.9-2.0-1.9-1.9-1.9-2.01.8-2.0-2.0-1.91.8-1.8-2.1-2.1-1.5-1.5-0.3
Patch foraging total patch changes 12 sec2.33.04.61.7-1.8-1.9-1.81.8-1.9-1.8-1.8-1.7-2.01.6-2.0-1.8-1.61.6-1.7-2.1-2.2-1.5-1.30.3
Patch foraging total patch changes 18 sec3.35.16.32.2-2.3-2.4-2.42.4-2.4-2.4-2.4-2.2-2.32.1-2.3-2.3-2.42.4-2.5-2.2-2.4-2.1-1.90.3
Patch foraging total patch changes 24 sec1.52.63.81.5-1.6-1.8-1.71.7-1.8-1.7-1.7-1.6-1.81.5-1.8-1.8-1.61.6-1.7-1.8-2.0-1.4-1.0-0.1
Patch foraging total patch changes 6 sec2.53.74.81.9-1.9-2.1-2.02.0-2.1-2.0-2.0-2.0-2.11.9-2.1-2.1-1.91.9-2.0-2.1-2.2-1.7-1.50.5
Patch foraging time to switch 0 sec1.83.76.52.1-2.0-1.9-1.91.9-1.9-2.0-1.9-2.0-1.92.0-1.8-1.7-2.02.0-1.8-1.8-1.9-1.9-2.5-0.5
Patch foraging water rate 0 sec2.55.38.9-2.52.42.32.4-2.32.32.42.42.42.2-2.42.12.12.5-2.52.42.12.02.23.00.8
Patch foraging water rate 12 sec2.55.26.1-2.42.52.42.3-2.32.42.42.32.32.3-2.32.32.32.2-2.22.32.42.12.42.3-0.6
Patch foraging water rate 18 sec0.40.63.3-0.70.70.60.6-0.60.60.60.70.60.5-0.80.50.50.7-0.70.80.50.41.00.7-1.8
Patch foraging water rate 24 sec2.94.14.6-2.02.12.12.1-2.12.12.12.12.02.1-2.02.12.02.0-2.02.12.02.12.02.1-0.4
Patch foraging water rate 6 sec4.16.08.5-2.72.62.52.5-2.52.52.52.52.72.5-2.52.42.32.4-2.42.62.52.32.42.9-0.5
Seeking ratio, delayed vs. immediate footshock0.20.21.7-0.40.30.30.4-0.30.30.40.40.30.3-0.20.30.20.4-0.40.30.20.30.01.01.3
Distance traveled before self-admin0.70.91.21.1-1.0-0.9-1.01.0-1.0-1.0-0.9-1.0-1.01.0-0.9-1.0-1.00.9-0.8-0.9-0.7-0.8-1.1-0.5
Distance traveled after self-admin0.30.31.70.5-0.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.50.7-0.5-0.5-0.50.5-0.5-0.4-0.4-0.7-0.21.3
Extensor digitorum longus weight3.614.321.6-4.03.83.84.0-3.93.84.04.13.83.2-4.33.23.84.4-4.44.52.83.44.63.0-1.3
Bone: elastic displacement4.24.86.62.4-2.2-2.2-2.22.1-2.1-2.2-2.2-2.4-1.82.6-1.8-1.9-2.42.4-2.5-1.9-1.6-2.5-2.51.0
Bone: elastic work0.10.10.50.10.20.20.1-0.20.30.10.10.10.60.20.60.4-0.30.3-0.30.60.7-0.4-0.6-0.1
Bone: endosteal estimation7.716.919.4-4.34.34.34.3-4.34.34.34.24.44.4-4.34.44.34.0-3.94.14.34.14.23.5-0.7
Bone: endosteal perimeter7.014.918.4-4.24.04.04.0-3.93.94.04.04.13.7-4.23.73.83.9-3.94.23.63.44.33.7-1.9
Epididymis fat weight0.82.93.7-1.81.81.81.7-1.81.81.81.71.71.9-1.61.91.71.6-1.61.41.91.91.31.71.0
Delta time in closed arm before/after self-admin0.00.00.1-0.0-0.1-0.1-0.10.1-0.1-0.1-0.1-0.10.00.10.0-0.1-0.20.2-0.2-0.1-0.2-0.20.10.3
Delta time in open arm before/after self-admin1.11.11.31.1-1.1-1.1-1.11.1-1.1-1.1-1.0-1.0-1.11.1-1.1-1.0-1.01.0-0.9-1.1-0.9-0.9-1.01.0
Diff in mean of infusions in LGA sessions1.01.21.5-1.01.21.11.1-1.21.21.11.11.01.2-1.01.21.21.0-1.01.01.11.20.81.00.6
Delay discount exponential model param0.60.61.00.7-0.8-0.8-0.90.8-0.8-0.9-0.9-0.8-0.60.9-0.7-0.8-1.01.0-1.0-0.6-0.6-0.8-0.7-0.2
Extinction: sum of active levers before priming1.51.62.5-1.41.31.41.4-1.41.41.41.41.21.4-1.21.41.41.2-1.21.31.31.61.01.1-0.0
Active lever presses in extinction session 61.21.21.5-1.11.11.21.1-1.11.11.11.11.21.1-1.01.11.11.1-1.11.21.11.01.10.90.2
Bone: final force10.617.019.8-4.34.34.34.3-4.34.34.34.34.54.2-4.14.24.34.2-4.24.24.14.23.74.00.3
Bone: final moment11.518.521.3-4.54.54.54.5-4.54.54.54.54.64.5-4.24.54.54.3-4.34.34.34.53.84.10.5
Food consumed during 24 hour testing period1.62.23.7-1.61.51.51.5-1.51.51.51.51.51.5-1.41.51.41.4-1.41.41.51.31.41.90.8
Glucose0.10.21.0-0.40.30.40.5-0.40.40.50.50.10.1-0.60.10.40.7-0.70.7-0.10.11.00.2-0.6
Heart weight0.10.10.2-0.30.30.30.3-0.30.30.30.30.20.2-0.50.20.30.5-0.50.40.20.20.40.1-0.4
Delay discount hyperbolic model param0.60.60.90.7-0.7-0.8-0.90.8-0.8-0.9-0.9-0.8-0.70.9-0.7-0.8-1.01.0-0.9-0.6-0.7-0.7-0.7-0.4
Intermittent access intake day 1-15 change0.30.69.30.3-0.3-0.3-0.30.4-0.4-0.4-0.3-0.3-0.50.0-0.5-0.4-0.20.2-0.2-0.3-0.6-0.0-0.6-3.1
Intermittent access intake escalation0.20.47.40.0-0.0-0.1-0.10.1-0.1-0.1-0.1-0.1-0.2-0.2-0.2-0.10.0-0.0-0.0-0.0-0.40.2-0.3-2.7
Intermittent access intake escalation 20.40.44.70.4-0.4-0.4-0.40.5-0.5-0.4-0.4-0.4-0.60.1-0.6-0.6-0.30.3-0.3-0.4-0.8-0.1-0.4-2.2
Intermitt. access day 1 inactive lever presses0.31.12.31.2-1.0-1.1-1.11.0-1.0-1.1-1.1-1.2-0.81.2-0.8-0.8-1.31.3-1.3-1.0-0.6-0.9-1.5-0.6
Intermitt. access day 15 inactive lever presses0.71.41.71.2-1.1-1.2-1.21.2-1.3-1.2-1.2-1.3-1.31.1-1.3-1.3-1.21.1-1.2-1.2-1.3-1.1-1.0-0.1
Intermitt. access escalation Index0.50.72.3-0.60.60.80.8-0.80.80.80.80.70.7-0.90.70.80.7-0.81.00.70.71.1-0.2-1.5
Intermittent access day 1 total infusions0.81.32.11.1-1.3-1.2-1.21.2-1.2-1.2-1.2-1.1-1.31.1-1.3-1.2-1.01.0-1.0-1.4-1.3-1.1-0.60.6
Intermittent access day 15 total infusions0.91.43.91.0-1.1-1.2-1.11.2-1.2-1.1-1.1-1.1-1.40.8-1.4-1.2-0.90.8-0.8-1.4-1.5-0.7-0.9-2.0
Intermittent access terminal intake (last 3 days)1.31.72.61.2-1.3-1.4-1.31.4-1.4-1.3-1.3-1.2-1.51.0-1.5-1.4-1.21.2-1.2-1.4-1.6-1.0-0.8-1.4
Intermittent access total infusions1.92.23.61.4-1.6-1.6-1.51.6-1.7-1.5-1.5-1.4-1.91.3-1.9-1.6-1.21.2-1.2-1.8-1.9-1.1-1.1-0.9
Intermittent access day 1 locomotion0.10.10.60.3-0.4-0.4-0.30.3-0.4-0.3-0.3-0.3-0.40.2-0.4-0.3-0.30.3-0.3-0.5-0.3-0.1-0.5-0.8
Intermittent access day 15 total locomotion0.40.78.70.3-0.5-0.6-0.50.6-0.6-0.5-0.5-0.4-0.60.1-0.7-0.5-0.40.4-0.4-0.7-0.70.1-0.7-2.9
Intermittent access total locomotion1.41.63.81.1-1.3-1.3-1.31.3-1.3-1.3-1.3-1.1-1.40.9-1.4-1.3-1.11.1-1.2-1.4-1.4-0.7-1.2-1.9
Intermittent access standard deviation0.30.72.20.8-0.8-0.8-0.70.8-0.8-0.7-0.7-0.8-1.00.5-1.0-0.6-0.50.5-0.5-0.9-0.9-0.4-1.1-1.5
Left kidney weight0.94.06.9-2.02.02.02.0-2.01.92.02.02.11.8-1.81.71.82.2-2.22.11.81.51.72.62.6
Right kidney weight4.018.120.7-4.44.44.44.5-4.44.44.54.54.34.2-4.34.24.24.5-4.54.44.13.94.24.50.7
Cocaine induced anxiety2.94.110.7-1.92.02.02.0-2.02.02.02.01.91.8-2.21.81.82.0-2.12.21.81.72.31.4-3.3
Post-drug Anxiety3.33.54.6-1.92.01.91.9-1.91.91.91.91.81.8-2.01.81.62.0-2.02.01.81.61.91.6-2.2
Baseline Anxiety0.10.11.9-0.10.20.10.1-0.10.10.10.10.10.10.00.10.20.2-0.20.10.10.2-0.20.31.4
Tail length0.10.35.0-0.10.10.00.1-0.10.00.10.1-0.0-0.1-0.2-0.10.00.3-0.30.2-0.3-0.30.60.42.2
Length with tail1.56.78.2-2.72.72.62.7-2.62.62.72.72.62.3-2.72.32.62.9-2.92.92.12.32.82.81.8
Length without tail5.216.920.3-4.24.34.34.3-4.34.34.34.44.34.0-4.24.04.24.4-4.54.53.94.04.04.00.4
Times rat made contact with spout0.20.21.60.2-0.4-0.3-0.30.3-0.3-0.3-0.2-0.4-0.50.4-0.5-0.4-0.10.0-0.1-0.6-0.5-0.30.41.3
Lifetime Intake2.42.95.11.6-1.8-1.8-1.71.8-1.9-1.7-1.7-1.6-2.21.4-2.2-1.9-1.31.3-1.3-2.1-2.3-1.3-1.1-0.9
Liver weight, left9.515.718.1-4.24.14.14.1-4.14.04.14.14.23.8-4.23.84.04.2-4.24.13.83.64.23.8-0.2
Liver weight, right2.64.65.8-2.22.22.22.2-2.22.22.22.22.32.3-2.22.32.22.1-2.02.02.42.12.12.00.2
Locomotor activity1.21.82.81.3-1.4-1.4-1.41.5-1.5-1.4-1.4-1.2-1.51.3-1.6-1.6-1.31.3-1.3-1.5-1.7-1.2-0.7-0.3
Locomotor testing distance2.64.76.12.1-2.3-2.3-2.32.3-2.4-2.3-2.3-2.0-2.42.1-2.4-2.5-2.22.2-2.1-2.3-2.5-1.9-1.5-0.5
Locomotor testing rearing1.93.94.82.0-2.1-2.0-2.02.1-2.1-2.0-2.0-2.0-2.21.7-2.2-2.1-1.91.9-1.7-2.0-2.2-1.4-2.0-1.5
Locomotion in novel chamber1.31.62.5-1.31.31.31.3-1.31.31.31.31.21.2-1.21.21.21.3-1.31.41.21.21.31.61.0
Locomotion in novel chamber post-restriction0.10.11.40.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.3-0.2-0.2-0.20.2-0.1-0.1-0.2-0.30.11.2
Fecal boli incidents, locomotor time 11.62.33.31.6-1.6-1.6-1.61.6-1.6-1.6-1.5-1.7-1.71.8-1.7-1.6-1.51.4-1.2-1.8-1.2-1.6-0.71.1
Change in fecal boli incidents, locomotor task0.90.81.2-0.91.00.90.9-0.91.00.90.90.91.1-0.81.11.00.8-0.80.61.01.10.51.00.9
Time >=10cm from walls, locomotor time 10.00.00.1-0.10.20.20.2-0.20.20.20.20.20.1-0.30.20.20.3-0.30.30.20.10.20.2-0.1
Bouts of movement, locomotor time 10.00.00.60.10.1-0.0-0.0-0.00.0-0.0-0.0-0.10.10.30.10.1-0.10.10.2-0.00.1-0.3-0.00.8
Total resting periods, locomotor time 10.30.31.00.6-0.5-0.5-0.50.5-0.5-0.5-0.5-0.6-0.40.8-0.4-0.4-0.70.7-0.3-0.5-0.4-0.8-0.51.0
Rest time, locomotor task time 10.40.52.10.7-0.6-0.6-0.60.6-0.6-0.6-0.6-0.8-0.70.9-0.7-0.6-0.50.5-0.3-0.8-0.8-0.8-0.21.4
Distance moved, locomotor task time 10.10.10.5-0.30.20.20.2-0.20.20.20.10.10.4-0.40.40.30.1-0.1-0.20.40.10.4-0.1-0.7
Vertical activity count, locomotor time 10.61.52.3-1.41.31.21.3-1.21.21.31.31.31.1-1.51.11.11.4-1.41.21.21.01.41.30.2
Time >=10cm from walls, locomotor time 20.60.91.70.9-1.1-1.0-0.91.0-1.0-0.9-0.9-0.9-1.11.1-1.1-0.8-0.80.8-0.8-1.1-0.9-1.1-0.41.3
Bouts of movement, locomotor time 21.93.13.9-1.82.01.81.8-1.81.81.81.81.81.8-1.81.81.71.8-1.81.81.71.81.61.7-0.1
Total resting periods, locomotor time 22.03.44.3-1.92.11.91.9-1.91.91.91.91.91.9-1.91.91.81.9-1.91.91.81.91.71.7-0.5
Rest time, locomotor task time 20.00.00.10.10.10.00.1-0.00.00.10.1-0.2-0.1-0.0-0.1-0.00.2-0.20.3-0.1-0.30.2-0.1-0.4
Distance moved, locomotor task time 20.10.10.60.1-0.3-0.2-0.30.2-0.2-0.3-0.3-0.2-0.00.3-0.0-0.1-0.40.4-0.70.0-0.1-0.4-0.30.8
Vertical activity count, locomotor time 20.10.11.2-0.40.20.20.2-0.10.10.20.20.40.0-0.4-0.0-0.00.3-0.30.20.1-0.20.50.81.1
Light reinforcement 12.15.06.22.1-2.3-2.4-2.42.4-2.4-2.4-2.4-2.1-2.22.0-2.2-2.4-2.52.5-2.4-2.2-2.3-1.7-2.1-1.6
Light reinforcement 20.71.11.41.0-1.1-1.1-1.11.1-1.1-1.1-1.2-1.0-1.11.0-1.1-1.1-1.21.2-1.1-1.0-1.1-0.9-1.0-0.1
Bone: marrow area7.516.518.8-4.24.24.34.2-4.24.34.24.24.34.3-4.24.34.23.9-3.94.04.34.14.23.4-0.8
Bone: maximum diameter4.17.612.4-3.12.82.82.8-2.72.72.82.93.02.4-3.02.42.53.0-3.03.12.42.13.13.5-0.4
Bone: maximum force15.327.231.0-5.45.55.55.4-5.55.55.45.45.55.6-5.35.65.55.2-5.15.15.55.54.94.4-0.6
Bone: maximum moment16.328.634.0-5.55.75.65.6-5.65.75.65.55.75.8-5.35.85.75.2-5.15.15.75.74.94.5-0.3
Mean time between licks in bursts0.10.20.80.6-0.4-0.4-0.40.4-0.4-0.4-0.5-0.4-0.20.6-0.1-0.3-0.60.6-0.7-0.0-0.1-0.9-0.60.7
Mean num. licks in bursts0.10.21.9-0.00.10.10.1-0.10.20.10.00.10.30.40.40.2-0.20.2-0.20.30.5-0.60.31.4
Cd content in liver0.91.02.01.1-1.0-0.9-1.00.9-0.9-1.0-0.9-1.3-0.91.1-0.9-0.8-1.01.0-0.8-0.9-0.8-0.8-1.4-0.7
Co content in liver0.30.31.00.3-0.6-0.5-0.40.5-0.6-0.4-0.4-0.5-0.90.2-1.0-0.7-0.10.00.0-0.9-1.00.1-0.3-0.0
Cu content in liver1.21.42.7-1.11.11.21.2-1.21.21.21.31.20.9-1.10.91.21.3-1.41.60.91.10.90.7-1.6
Fe content in liver1.82.23.21.5-1.6-1.6-1.51.5-1.6-1.5-1.5-1.4-1.71.4-1.7-1.5-1.31.2-1.3-1.8-1.5-1.6-1.0-0.2
K content in liver0.10.10.3-0.2-0.00.00.1-0.10.00.10.20.2-0.3-0.2-0.30.10.5-0.50.5-0.5-0.10.30.10.0
Mg content in liver0.20.21.90.2-0.3-0.3-0.30.3-0.4-0.3-0.3-0.2-0.40.4-0.5-0.4-0.10.1-0.1-0.5-0.4-0.40.41.4
Mn content in liver0.10.11.10.0-0.00.0-0.0-0.00.1-0.0-0.1-0.10.30.30.30.1-0.20.3-0.40.20.4-0.40.21.0
Na content in liver0.10.21.20.3-0.3-0.3-0.20.2-0.2-0.2-0.1-0.3-0.50.0-0.5-0.10.1-0.10.1-0.6-0.30.2-0.9-1.1
Rb content in liver0.10.10.50.2-0.3-0.2-0.10.1-0.2-0.1-0.0-0.2-0.5-0.0-0.5-0.10.3-0.40.3-0.7-0.3-0.10.0-0.3
Se content in liver1.51.72.61.2-1.5-1.4-1.41.4-1.4-1.3-1.3-1.2-1.51.2-1.5-1.5-1.21.1-1.2-1.4-1.6-1.3-0.7-0.8
Sr content in liver1.61.42.6-1.21.21.21.2-1.21.21.21.21.31.0-1.31.01.11.2-1.21.41.10.91.61.0-1.0
Zn content in liver0.80.91.60.9-1.1-1.0-1.01.0-1.1-1.0-1.0-0.8-1.20.9-1.2-1.1-0.90.9-0.7-1.2-1.2-0.7-0.6-0.3
Bone: minimum diameter9.317.018.9-4.44.34.34.3-4.34.34.34.34.44.1-4.34.14.24.2-4.24.44.03.94.33.9-1.3
Time in familiar zone, hab. session 10.30.31.00.4-0.4-0.5-0.50.4-0.4-0.5-0.5-0.4-0.40.6-0.4-0.4-0.50.5-0.5-0.4-0.3-0.90.01.0
Time in novel zone, hab. session 10.40.41.3-0.60.60.50.5-0.50.50.50.50.60.5-0.70.50.40.6-0.60.50.50.30.80.7-1.1
Total zone transitions, hab. session 10.40.50.70.8-0.7-0.7-0.70.7-0.7-0.7-0.7-0.6-0.80.7-0.8-0.7-0.60.6-0.6-0.8-0.6-0.7-0.80.4
Total locomotion distance, hab. session 10.00.00.2-0.00.20.20.1-0.10.20.10.10.10.30.10.30.2-0.10.2-0.00.40.3-0.2-0.00.4
Locomotion velocity, hab. session 10.00.10.3-0.10.30.30.2-0.20.20.20.20.30.4-0.00.40.3-0.00.10.10.50.4-0.0-0.10.4
Time in familiar zone, hab. session 20.40.41.2-0.50.60.60.6-0.60.60.60.60.60.7-0.40.70.70.5-0.40.40.60.80.10.71.1
Time in novel zone, hab. session 20.30.32.30.4-0.5-0.5-0.50.5-0.5-0.5-0.5-0.4-0.50.3-0.5-0.5-0.50.5-0.4-0.4-0.60.1-0.7-1.5
Total zone transitions, hab. session 20.30.40.70.7-0.6-0.6-0.60.6-0.6-0.6-0.6-0.5-0.70.7-0.7-0.5-0.50.5-0.5-0.7-0.5-0.9-0.60.6
Total locomotion distance, hab. session 20.10.10.60.4-0.2-0.2-0.30.2-0.2-0.3-0.3-0.2-0.00.50.0-0.2-0.50.5-0.40.20.0-0.7-0.40.8
Locomotion velocity, hab. session 20.10.10.70.2-0.0-0.0-0.10.1-0.0-0.1-0.1-0.10.10.40.1-0.0-0.30.3-0.20.30.1-0.6-0.20.8
Novel to familiar place preference ratio1.71.83.8-1.41.31.41.4-1.41.41.41.41.31.4-1.71.41.41.4-1.41.41.21.22.00.6-0.6
Novelty place preference1.31.43.1-1.21.11.21.2-1.21.21.21.21.11.2-1.51.21.21.2-1.21.11.01.11.80.5-0.5
Time in novel zone, NPP test1.11.22.9-1.11.01.11.1-1.11.11.11.11.01.1-1.41.11.11.0-1.01.00.91.01.70.4-0.7
Total zone transitions, NPP test1.31.92.91.5-1.5-1.4-1.41.4-1.4-1.4-1.4-1.3-1.51.5-1.5-1.3-1.31.3-1.1-1.5-1.1-1.7-1.31.3
Total locomotion distance, NPP test1.52.13.31.6-1.4-1.4-1.51.5-1.4-1.5-1.5-1.4-1.31.7-1.2-1.4-1.71.7-1.5-1.1-1.1-1.8-1.50.7
Locomotion velocity, NPP test0.81.22.11.2-1.1-1.0-1.11.1-1.0-1.1-1.1-1.0-1.01.3-0.9-1.1-1.21.2-1.0-0.7-0.8-1.4-1.10.9
Intraocular pressure6.59.311.03.1-3.1-3.1-3.23.2-3.2-3.2-3.2-3.0-3.03.3-3.0-3.3-3.33.3-3.3-2.7-3.1-3.2-2.41.6
Delta distance traveled before/after self-admin0.10.11.5-0.10.10.10.1-0.10.10.10.10.10.10.00.10.10.0-0.0-0.00.1-0.0-0.20.41.2
Delta ambulatory time before/after self-admin0.00.00.20.1-0.1-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.1-0.3-0.2-0.10.1-0.2-0.2-0.5-0.20.20.5
Parametrial fat weight1.02.23.41.4-1.6-1.6-1.51.6-1.6-1.5-1.5-1.5-1.81.3-1.8-1.8-1.31.3-1.3-1.8-1.8-1.4-0.80.6
Pavlov. Cond. lever latency0.20.31.2-0.20.50.40.4-0.50.60.40.30.21.0-0.11.00.7-0.10.1-0.20.91.1-0.1-0.20.3
Pavlov. Cond. magazine entry latency0.10.11.50.1-0.2-0.2-0.20.2-0.2-0.2-0.20.0-0.10.1-0.1-0.2-0.20.2-0.2-0.1-0.2-0.1-0.2-1.2
Pavlov. Cond. change in total contacts0.20.23.3-0.2-0.00.00.1-0.0-0.00.10.10.2-0.3-0.4-0.3-0.10.4-0.40.4-0.2-0.40.50.1-1.8
Pavlov. Cond. index score0.10.21.6-0.2-0.10.00.10.0-0.10.10.10.2-0.4-0.4-0.4-0.20.4-0.40.5-0.3-0.50.60.2-1.3
Pavlov. Cond. latency score0.10.21.1-0.2-0.1-0.00.00.1-0.10.00.10.2-0.5-0.3-0.5-0.30.4-0.40.5-0.4-0.60.50.3-1.0
Pavlov. Cond. lever contacts0.60.71.80.6-0.9-0.8-0.70.8-0.9-0.7-0.7-0.7-1.30.4-1.3-1.0-0.30.3-0.2-1.3-1.3-0.1-0.5-1.0
Pavlov. Cond. magazine entry number0.10.11.7-0.00.10.10.1-0.10.10.10.1-0.00.20.10.30.2-0.00.0-0.10.20.3-0.20.11.3
Pavlov. Cond. intertrial magazine entries0.40.52.00.7-0.6-0.6-0.60.6-0.6-0.6-0.6-0.8-0.61.0-0.5-0.5-0.70.7-0.6-0.7-0.3-1.3-0.21.4
Pavlov. Cond. lever-magazine prob. diff.0.20.21.3-0.40.20.20.3-0.20.20.30.40.4-0.2-0.6-0.20.10.6-0.70.8-0.2-0.20.80.3-1.1
Pavlov. Cond. response bias0.20.21.40.3-0.5-0.4-0.40.5-0.5-0.4-0.4-0.3-0.60.3-0.6-0.5-0.30.3-0.2-0.6-0.6-0.1-0.4-1.2
Pavlov. Cond. lever latency0.10.10.4-0.30.30.30.3-0.30.40.30.30.40.4-0.20.40.50.2-0.20.20.40.50.10.10.6
Pavlov. Cond. magazine entry latency1.11.41.6-1.31.21.21.2-1.21.21.21.21.21.2-1.21.21.11.1-1.11.11.11.11.21.1-1.2
Pavlov. Cond. change in total contacts1.42.23.8-1.61.41.51.6-1.51.51.61.61.31.2-1.71.11.41.8-1.81.91.01.12.01.5-0.6
Pavlov. Cond. index score0.70.91.6-1.00.90.91.0-0.90.91.01.00.80.8-1.00.80.91.0-1.11.10.70.71.20.9-1.3
Pavlov. Cond. latency score0.60.81.1-0.90.80.90.9-0.90.80.90.90.80.7-1.00.70.81.0-1.01.00.70.71.01.0-1.0
Pavlov. Cond. lever contacts0.00.10.40.1-0.1-0.2-0.10.2-0.2-0.1-0.1-0.2-0.30.1-0.3-0.3-0.00.0-0.0-0.2-0.40.10.1-0.7
Pavlov. Cond. magazine entry number2.43.03.71.8-1.8-1.8-1.81.8-1.7-1.8-1.8-1.7-1.61.9-1.6-1.7-1.81.8-1.9-1.6-1.6-1.9-1.61.6
Pavlov. Cond. intertrial magazine entries5.58.39.82.9-3.0-3.0-3.03.0-3.0-3.0-3.0-2.9-2.93.1-2.9-3.0-2.92.9-3.0-2.9-2.9-3.1-2.02.0
Pavlov. Cond. lever-magazine prob. diff.0.91.21.8-1.21.11.11.1-1.11.11.11.21.00.9-1.20.91.01.2-1.21.20.90.91.31.1-1.3
Pavlov. Cond. response bias0.10.11.4-0.30.30.20.3-0.30.20.30.30.20.2-0.40.10.20.3-0.40.30.10.10.50.3-1.2
Time in closed arm before self-admin2.33.03.9-1.71.71.81.7-1.71.71.71.81.81.6-2.01.61.61.8-1.71.91.71.72.01.1-1.5
Time in closed arm after self-admin0.20.20.3-0.40.40.40.4-0.40.40.40.40.50.5-0.50.50.30.3-0.20.30.50.40.40.2-0.6
Time in open arm before self-admin0.20.23.60.1-0.1-0.2-0.20.2-0.2-0.2-0.2-0.3-0.00.2-0.1-0.1-0.20.2-0.4-0.0-0.3-0.0-0.4-1.9
Time in open arm after self-admin0.10.11.70.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.3-0.20.4-0.20.0-0.20.2-0.2-0.3-0.1-0.1-0.21.3
Bone: periosteal estimation12.726.731.0-5.55.45.45.4-5.35.35.45.45.65.2-5.45.15.15.3-5.35.45.14.85.35.2-0.6
Bone: periosteal perimeter10.818.621.9-4.74.54.54.5-4.44.44.54.54.64.3-4.54.24.34.5-4.44.64.14.04.44.6-0.6
Bone: post-yield work8.712.814.9-3.73.83.73.7-3.73.73.73.73.83.9-3.83.83.83.5-3.43.43.73.73.63.0-1.0
Progressive ratio test 1 active lever presses5.56.89.02.6-2.8-2.8-2.72.8-2.8-2.7-2.7-2.6-3.02.4-3.0-2.7-2.42.4-2.2-2.9-3.0-2.0-2.5-0.9
Progressive ratio test 1 breakpoint5.16.28.52.5-2.7-2.6-2.62.6-2.7-2.6-2.5-2.5-2.92.2-2.9-2.6-2.32.3-2.1-2.9-2.9-1.8-2.4-1.0
Progressive ratio test 1 inactive lever presses2.02.94.51.7-1.9-1.9-1.81.8-1.9-1.8-1.7-1.6-2.01.5-2.0-2.0-1.51.5-1.5-2.1-2.0-1.3-1.4-0.1
Progressive ratio test 2 active lever presses2.02.43.71.5-1.5-1.6-1.61.6-1.7-1.6-1.6-1.7-1.81.3-1.8-1.7-1.41.3-1.2-1.6-1.9-1.0-1.6-1.0
Progressive ratio test 2 breakpoint2.02.23.51.5-1.5-1.5-1.51.6-1.6-1.5-1.5-1.6-1.81.3-1.8-1.6-1.31.3-1.2-1.6-1.9-0.9-1.6-1.1
Progressive ratio test 2 inactive lever presses1.22.03.01.3-1.3-1.5-1.41.5-1.5-1.4-1.4-1.5-1.71.2-1.7-1.6-1.21.2-1.2-1.6-1.7-1.0-1.2-1.2
Incentive Sensitization - Responses0.20.20.8-0.60.70.40.4-0.40.30.40.40.40.2-0.60.20.20.6-0.60.60.50.00.50.9-0.3
Incentive Sensitization - Breakpoint0.10.10.4-0.50.60.30.3-0.20.20.30.30.30.1-0.40.10.10.4-0.40.50.4-0.10.40.7-0.4
Sum of active levers in priming session hrs 5-60.10.10.60.00.10.10.1-0.20.20.10.1-0.00.3-0.00.30.4-0.00.00.00.10.50.1-0.5-0.8
Progressive ratio0.20.20.50.4-0.5-0.5-0.50.6-0.6-0.5-0.5-0.4-0.50.4-0.6-0.7-0.50.5-0.5-0.4-0.7-0.40.1-0.3
Food seeking constrained by brief footshock0.91.12.31.0-1.1-1.0-1.01.1-1.1-1.0-1.0-1.0-1.20.8-1.2-1.1-0.80.8-0.7-1.2-1.1-0.8-0.9-1.5
Seeking ratio, punishment vs. effort0.00.00.30.2-0.2-0.2-0.10.1-0.1-0.1-0.1-0.2-0.20.2-0.20.0-0.10.10.0-0.3-0.1-0.2-0.6-0.3
Retroperitoneal fat weight0.41.55.41.0-1.2-1.2-1.11.1-1.2-1.1-1.1-1.2-1.11.4-1.1-1.2-1.11.1-1.2-1.2-1.0-1.6-0.22.3
Reaction time number correct1.12.24.0-1.51.61.61.4-1.51.51.41.41.61.8-1.11.81.51.1-1.01.12.01.90.91.7-0.5
Reaction time mean minus median4.310.612.33.5-3.4-3.4-3.43.4-3.4-3.4-3.4-3.4-3.43.3-3.4-3.5-3.23.2-3.2-3.4-3.3-3.2-2.8-0.1
Reaction time mean minus median AUC3.07.58.83.0-2.8-2.8-2.82.8-2.8-2.8-2.8-2.9-2.82.8-2.7-2.9-2.82.8-2.8-2.7-2.7-2.7-2.6-1.1
Reaction time num false alarms1.31.92.61.4-1.4-1.4-1.41.4-1.4-1.4-1.5-1.4-1.31.5-1.3-1.4-1.51.5-1.6-1.2-1.4-1.5-1.00.5
Reaction time num false alarms AUC1.82.83.91.8-1.7-1.7-1.81.7-1.7-1.7-1.8-1.8-1.61.8-1.6-1.7-1.81.8-2.0-1.4-1.7-1.8-1.50.2
Reaction time trials correct on left1.12.24.0-1.51.61.61.4-1.51.51.41.41.61.8-1.11.81.51.1-1.01.12.01.90.91.7-0.5
Reaction time trials on left0.91.73.4-1.31.41.41.2-1.31.41.21.21.41.6-0.91.71.30.9-0.80.91.81.70.71.5-0.5
Reaction time mean0.61.01.51.1-1.0-1.0-1.01.0-1.1-1.0-1.0-1.1-1.20.9-1.2-1.1-0.80.7-0.8-1.1-1.1-0.8-0.80.2
Reaction time mean AUC0.30.50.90.8-0.7-0.8-0.70.8-0.8-0.7-0.7-0.8-1.00.7-1.0-0.8-0.50.5-0.5-0.9-0.9-0.6-0.50.2
Median of all reaction times0.00.00.1-0.00.10.00.1-0.00.00.10.10.0-0.2-0.2-0.2-0.00.3-0.30.3-0.1-0.10.30.10.2
Reaction time omissions9.313.615.93.8-3.8-3.8-3.93.8-3.8-3.9-3.9-3.9-3.74.0-3.7-3.9-3.93.9-3.8-3.6-3.5-3.9-2.81.2
Reaction time false alarm rate2.43.34.31.9-1.9-1.9-1.91.9-1.9-1.9-1.9-2.0-1.91.8-1.9-1.9-1.71.7-1.9-1.9-2.1-1.7-1.80.6
Reaction time premature initiation rate5.47.410.32.7-2.9-2.9-2.82.9-3.0-2.8-2.8-2.7-3.22.5-3.2-3.1-2.52.4-2.4-3.2-3.1-2.2-2.10.1
Reaction time premature initiations1.93.34.71.8-1.9-2.0-1.92.0-2.0-1.9-1.9-1.8-2.01.8-2.0-2.2-1.81.8-1.7-1.9-1.9-1.7-1.1-0.3
Std. dev. reaction times4.68.49.63.1-3.0-3.0-3.03.0-3.0-3.0-3.0-3.1-3.13.0-3.1-3.1-2.92.8-2.9-3.0-2.9-2.9-2.50.1
Reaction time trials completed0.91.73.4-1.31.41.41.2-1.31.41.21.21.41.6-0.91.71.30.9-0.80.91.81.70.71.5-0.5
Reaction time trials AUC1.42.74.8-1.71.81.71.6-1.71.71.61.61.72.0-1.22.11.71.2-1.11.32.22.11.01.8-0.3
Run reversals in cocaine runway, females0.00.00.1-0.20.10.10.1-0.20.20.10.10.10.3-0.20.30.30.0-0.0-0.20.10.20.2-0.0-0.3
Run reversals in cocaine runway, males1.21.21.41.1-1.1-1.1-1.11.1-1.1-1.1-1.1-1.0-1.11.1-1.1-1.1-1.11.1-1.2-1.2-1.1-1.1-0.80.5
Latency to leave start box in cocaine runway0.00.00.30.1-0.1-0.2-0.20.2-0.2-0.2-0.2-0.1-0.20.0-0.2-0.2-0.10.1-0.1-0.2-0.2-0.10.10.6
Latency to leave start box in cocaine runway, F0.91.11.31.0-1.0-1.1-1.11.1-1.1-1.1-1.1-1.0-1.10.9-1.1-1.2-1.11.1-1.0-1.0-1.1-0.9-0.9-0.2
Latency to leave start box in cocaine runway, M1.81.72.2-1.31.31.31.3-1.31.31.31.31.31.2-1.31.21.31.4-1.41.21.11.21.21.51.3
Std. dev. time between licks in bursts0.81.12.01.1-1.0-1.1-1.11.1-1.2-1.1-1.1-1.0-1.20.9-1.2-1.3-0.90.9-1.0-1.0-1.4-0.9-0.8-0.1
Total sessions with >9 infusions2.22.75.31.5-1.7-1.7-1.71.8-1.9-1.7-1.6-1.5-2.21.3-2.2-2.0-1.31.3-1.1-2.0-2.3-1.2-0.7-0.5
Short access day 1 total inactive lever presses1.92.43.71.5-1.7-1.6-1.61.6-1.7-1.6-1.5-1.5-1.91.4-1.9-1.6-1.31.3-1.2-1.9-1.9-1.1-1.4-1.2
Short access day 10 total inactive lever presses0.10.21.10.5-0.4-0.4-0.40.3-0.3-0.4-0.4-0.5-0.20.5-0.2-0.3-0.50.5-0.5-0.4-0.0-0.4-1.1-0.5
Short access day 1 total infusions0.70.92.00.9-1.0-1.0-0.91.0-1.1-0.9-0.9-0.8-1.30.8-1.3-1.2-0.70.6-0.5-1.2-1.4-0.6-0.4-0.2
Short access day 10 total infusions1.62.03.91.3-1.6-1.5-1.41.5-1.6-1.4-1.4-1.2-1.91.1-2.0-1.5-1.01.0-0.9-2.0-1.9-0.9-0.8-0.4
Short access total infusions2.53.26.01.6-1.9-1.9-1.81.9-2.0-1.8-1.8-1.6-2.31.4-2.4-2.1-1.41.4-1.3-2.2-2.5-1.2-1.0-0.7
Short access day 1 locomotion0.20.30.70.5-0.6-0.5-0.50.5-0.6-0.5-0.4-0.4-0.80.2-0.8-0.7-0.20.2-0.1-0.8-0.80.0-0.4-0.3
Short access day 10 total locomotion0.20.30.60.6-0.7-0.6-0.60.6-0.6-0.6-0.6-0.5-0.60.5-0.6-0.5-0.60.6-0.6-0.8-0.5-0.2-0.7-0.6
Short access total locomotion0.91.11.91.0-1.2-1.1-1.11.1-1.1-1.1-1.0-1.0-1.30.8-1.3-1.1-0.90.9-0.8-1.4-1.2-0.5-1.0-0.8
One hour access (0.3 mA shock)0.30.32.00.3-0.5-0.5-0.40.5-0.5-0.4-0.4-0.3-0.80.1-0.8-0.6-0.10.1-0.1-0.7-1.00.0-0.0-1.4
Compulsive drug intake0.30.47.60.0-0.0-0.0-0.00.0-0.0-0.0-0.00.00.10.20.10.1-0.20.2-0.1-0.00.1-0.20.32.8
One hour access (shock baseline)0.30.58.1-0.1-0.0-0.1-0.10.1-0.2-0.1-0.00.0-0.4-0.3-0.5-0.40.3-0.30.3-0.3-0.60.30.2-2.9
Social response proportion0.20.20.70.4-0.4-0.4-0.40.4-0.5-0.4-0.4-0.5-0.60.3-0.6-0.6-0.20.2-0.2-0.6-0.8-0.1-0.20.3
Social responses7.29.212.03.2-3.2-3.2-3.23.2-3.2-3.1-3.1-3.2-3.32.9-3.3-3.3-2.92.8-3.0-3.3-3.5-2.5-2.7-0.8
Social time0.00.00.8-0.00.00.00.1-0.10.10.10.10.00.10.10.10.10.0-0.00.2-0.10.2-0.00.10.9
Soleus weight0.51.52.1-1.31.21.31.3-1.31.31.31.31.21.3-1.31.21.51.3-1.31.31.01.31.40.5-0.2
Bone: stiffness17.728.832.6-5.65.75.65.6-5.65.65.65.65.75.6-5.65.65.55.4-5.45.45.65.35.34.7-1.3
Tibialis anterior weight0.82.88.0-1.61.31.51.7-1.61.51.71.81.40.9-2.20.91.52.2-2.32.40.51.02.80.6-1.6
Time to tail flick, vehicle, before self-admin1.61.62.41.3-1.2-1.3-1.31.3-1.2-1.3-1.3-1.4-1.01.5-1.0-1.3-1.41.5-1.4-1.0-1.2-1.5-1.11.1
Time to tail flick, vehicle, after self-admin0.10.10.9-0.20.30.30.3-0.30.30.30.30.40.3-0.30.30.40.2-0.20.30.40.50.5-0.3-0.9
Time to tail flick, test, before self-admin0.40.41.50.5-0.5-0.5-0.50.5-0.4-0.5-0.5-0.5-0.30.8-0.3-0.2-0.60.7-0.8-0.40.0-1.1-0.61.2
Time to tail flick, test, after self-admin0.70.71.1-0.90.90.90.9-0.90.90.80.80.90.9-0.90.90.90.8-0.80.81.01.00.60.7-0.4
Delta time to tail flick, vehicle, before/after SA0.50.50.8-0.60.60.70.7-0.70.70.70.70.80.5-0.80.50.70.7-0.80.90.50.80.90.3-0.8
Delta time to tail flick, test, before/after SA0.30.30.6-0.60.50.50.5-0.50.50.50.50.60.4-0.70.40.20.6-0.60.70.50.30.80.7-0.6
Tibia length7.219.824.4-4.64.64.64.7-4.64.64.74.74.74.2-4.84.24.54.9-4.94.84.24.04.74.00.7
Ambulatory time before self-admin1.72.53.51.8-1.7-1.6-1.61.6-1.6-1.6-1.6-1.7-1.61.7-1.6-1.6-1.71.7-1.5-1.6-1.3-1.5-1.9-0.3
Ambulatory time after self-admin1.11.31.61.1-1.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.31.2-1.3-1.2-1.11.1-1.0-1.1-1.3-1.1-0.90.6
Bone: tissue strength1.11.12.3-0.91.11.11.1-1.11.21.11.00.91.4-0.91.41.40.8-0.80.71.21.50.70.20.0
Total heroin consumption0.91.01.7-1.00.91.01.0-1.01.01.01.00.91.0-1.11.01.21.0-1.00.80.91.11.30.3-1.3
Bone: trabecular number6.110.212.5-3.43.43.33.3-3.33.33.33.33.33.4-3.13.43.23.1-3.13.03.53.32.73.40.8
Bone: trabecular spacing2.33.14.11.8-1.8-1.9-1.81.9-1.9-1.8-1.8-1.7-2.01.7-2.0-1.9-1.61.6-1.6-2.0-1.9-1.4-1.40.3
Bone: trabecular thickness0.00.10.10.2-0.2-0.2-0.30.3-0.3-0.3-0.2-0.3-0.30.3-0.3-0.3-0.30.3-0.2-0.2-0.4-0.1-0.10.0
Bone: trabecular tissue density0.00.00.10.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.00.10.10.1-0.0-0.20.2-0.30.2-0.1-0.2-0.1-0.1
Water consumed over 24 hours0.10.10.2-0.40.40.40.3-0.30.40.30.30.40.5-0.30.50.40.2-0.20.20.50.40.20.5-0.1
Number of responses in last shaping day0.50.68.50.3-0.3-0.3-0.30.4-0.4-0.3-0.3-0.4-0.6-0.0-0.6-0.4-0.10.10.1-0.4-0.70.5-0.9-2.9