Hub : Genes

Gucy2g

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Gucy2g 0.02 0.02 2.7e-03 0.01 0.01 0.02 0.01 1.9e-02 1.9e-02 6.5e-03 2.0e-02
2 LHb gene expression Gucy2g 0.47 0.19 8.1e-10 0.33 0.36 0.37 0.37 1.3e-08 2.3e-09 9.6e-10 1.2e-09
3 PL gene expression Gucy2g 0.09 0.06 1.5e-07 0.04 0.06 0.05 0.06 1.6e-05 4.9e-07 2.5e-06 3.9e-07
4 NAcc alternative TSS NM_139042.2 0.04 0.03 1.2e-05 0.04 0.04 0.04 0.02 3.6e-06 3.0e-06 2.1e-06 9.4e-04
5 BLA gene expression Gucy2g 0.11 0.07 3.3e-05 0.08 0.06 0.04 0.07 7.3e-05 3.8e-04 3.3e-03 1.8e-04
6 Liver gene expression Gucy2g 0.05 0.04 2.9e-06 0.04 0.03 0.04 0.03 1.4e-05 1.9e-04 3.9e-05 1.5e-04
7 PL alternative TSS XM_039097457.2 0.03 0.02 8.3e-03 0.01 0.01 0.01 0.01 9.2e-03 2.5e-02 7.1e-02 4.2e-02
8 NAcc gene expression Gucy2g 0.29 0.14 0.0e+00 0.15 0.16 0.16 0.15 1.4e-22 1.0e-23 1.0e-23 3.4e-22
9 NAcc alternative TSS XM_039097497.2 0.03 0.02 4.1e-03 0 0.01 0.01 0.01 5.1e-02 3.9e-03 4.2e-03 2.4e-02
10 IC alternative TSS XM_039097497.2 0.11 0.13 8.0e-03 0.01 -0.01 0.01 0.02 9.5e-02 7.4e-01 8.9e-02 3.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.71.25.42.31.5-1.2-1.00.50.5-0.50.30.90.5
Area under the delay curve0.30.41.31.00.3-0.10.1-0.4-0.30.4-0.61.11.0
BMI with tail7.225.245.46.76.7-6.4-5.84.84.7-4.73.9-1.3-2.0
BMI without tail2.412.621.84.14.7-4.7-3.43.73.4-3.43.6-1.3-1.5
Body weight7.432.462.77.97.7-7.2-6.35.35.3-5.34.6-1.1-2.1
Weight adjusted by age2.06.09.61.63.1-3.1-2.62.72.5-2.42.7-1.6-1.5
Bone surface0.40.82.41.61.3-1.3-0.90.90.6-0.60.60.2-0.1
Bone volume1.63.18.83.02.5-2.2-2.01.51.4-1.41.10.2-0.2
Breakpoint value in progressive ratio session0.50.82.40.90.20.00.2-0.7-0.80.7-1.01.61.5
Number of licking bursts0.20.61.81.00.3-0.30.2-0.2-0.60.6-0.71.31.2
Context. condit. distance diff. score0.50.61.5-0.9-0.3-0.00.40.50.5-0.51.2-1.2-1.1
Locomotion velocity, session 12.73.03.8-1.6-2.01.81.7-1.7-1.91.9-1.81.31.5
Locomotion distance, session 10.20.20.8-0.9-0.50.30.50.1-0.00.00.4-0.6-0.5
Locomotion velocity, session 20.60.72.1-1.2-0.60.20.20.60.5-0.50.9-1.5-1.3
Locomotion distance, session 21.11.52.31.41.5-1.5-1.21.31.3-1.31.3-0.5-0.6
Locomotion velocity, session 30.30.31.1-0.3-0.1-0.20.30.40.5-0.51.1-0.7-0.7
Locomotion distance, session 31.51.74.4-0.10.6-0.8-0.51.11.4-1.42.1-1.8-1.8
Stereotopy head waving bouts, day 30.10.10.20.40.3-0.2-0.30.00.1-0.1-0.40.20.1
Stereotopy head waving duration, day 31.11.42.3-0.9-1.01.01.2-1.0-1.41.3-1.51.11.2
Locomotion velocity, session 70.00.00.10.20.2-0.10.00.10.0-0.00.30.1-0.0
Locomotion distance, session 70.20.20.6-0.4-0.0-0.10.00.30.4-0.30.8-0.7-0.7
Stereotopy head waving bouts, day 70.00.00.10.30.2-0.3-0.00.1-0.10.1-0.20.30.2
Stereotopy head waving duration, day 70.20.20.60.80.5-0.7-0.10.3-0.20.2-0.30.70.6
Locomotion velocity, session 80.60.71.8-1.3-1.31.21.0-0.6-0.70.6-0.4-0.2-0.1
Locomotion distance, session 80.40.62.0-0.7-0.1-0.20.30.70.6-0.61.4-1.2-1.1
Degree of sensitization distance1.81.93.4-0.7-1.11.21.1-1.3-1.61.6-1.81.61.6
Degree of sensitization stereotypy0.10.10.40.30.2-0.20.1-0.1-0.20.2-0.30.60.6
Conditioned locomotion0.00.00.10.0-0.00.1-0.10.20.3-0.20.4-0.3-0.3
Cocaine response after cond. corrected0.50.73.2-1.8-1.00.71.0-0.2-0.20.20.6-0.9-0.5
Cocaine response after cond. not corrected0.81.24.5-2.1-1.61.31.3-0.7-0.70.7-0.1-0.5-0.2
Cocaine response before conditioning0.91.02.4-0.2-0.91.10.5-1.1-1.11.1-1.51.00.9
Saline control response0.40.51.6-1.2-1.11.00.6-0.6-0.40.5-0.4-0.4-0.3
Bone: connectivity density0.00.10.10.1-0.20.20.3-0.2-0.30.2-0.10.30.2
Bone: cortical apparent density1.32.06.4-1.9-0.80.40.20.80.8-0.81.5-2.5-2.2
Bone: cortical area3.15.011.43.43.3-3.3-1.92.41.5-1.61.80.50.2
Bone: cortical porosity0.30.30.80.2-0.40.40.5-0.5-0.50.5-0.50.90.8
Bone: cortical porosity0.40.41.50.70.00.20.4-0.5-0.50.4-0.51.21.1
Bone: cortical thickness2.33.86.72.42.6-2.6-1.72.21.8-1.82.1-0.4-0.7
Bone: cortical thickness2.22.73.81.71.9-1.9-1.81.91.7-1.71.4-0.9-1.1
Bone: cortical tissue density1.21.96.1-2.0-0.90.50.30.70.7-0.71.4-2.5-2.1
Condit. Reinf. active minus inactive responses0.40.41.0-1.0-0.50.51.0-0.4-0.70.7-0.20.40.6
Condit. Reinf. active-inactive response ratio0.70.71.7-1.3-0.90.71.2-0.7-0.90.9-0.40.40.6
Condit. Reinf. active responses0.10.10.50.10.10.00.4-0.2-0.30.30.00.70.7
Condit. Reinf. inactive responses0.20.31.21.10.5-0.3-0.2-0.1-0.00.0-0.00.90.8
Incentive salience index mean0.91.12.2-1.5-1.11.11.4-1.0-1.11.1-0.60.60.8
Condit. Reinf. lever presses0.91.42.0-1.2-1.31.41.2-1.4-1.21.2-1.10.91.0
Condit. Reinf. active minus inactive responses2.43.67.2-0.9-0.90.82.4-1.3-2.32.3-1.42.62.7
Condit. Reinf. active-inactive response ratio1.82.95.3-1.4-1.20.82.3-1.2-2.12.1-1.21.92.1
Condit. Reinf. active responses1.82.67.00.1-0.20.21.6-1.0-1.91.9-1.12.62.6
Condit. Reinf. inactive responses0.30.41.40.80.4-0.00.2-0.4-0.40.4-0.21.21.1
Condit. Reinf. lever presses1.11.64.10.0-0.40.41.1-0.9-1.51.5-1.22.01.9
Condit. Reinf. lever reinforcers received1.82.66.5-0.0-0.30.31.7-1.1-1.91.9-1.12.62.5
Conditioned reinforcement - actives0.10.61.1-0.2-0.50.60.8-0.8-0.90.9-0.61.01.0
Conditioned reinforcement - inactives0.10.20.60.80.6-0.2-0.3-0.1-0.10.3-0.20.70.7
Conditioned locomotion0.10.20.60.80.0-0.1-0.50.40.3-0.3-0.1-0.3-0.6
Patch foraging indifference point 0 sec0.92.54.62.12.1-2.0-1.71.41.6-1.61.4-0.2-0.6
Patch foraging indifference point AUC0.61.33.61.3-0.00.5-0.2-1.1-0.80.9-1.61.91.5
Delay disc. indifference point, 0s delay0.60.62.41.51.0-0.9-0.80.60.7-0.70.30.0-0.2
Delay disc. indifference point, 16s delay0.50.81.80.2-0.30.50.5-0.9-0.90.9-1.11.31.3
Delay disc. indifference point, 2s delay0.10.10.50.70.1-0.1-0.20.10.2-0.2-0.1-0.0-0.1
Delay disc. indifference point, 24s delay1.01.54.20.9-0.00.30.2-1.1-1.01.1-1.72.11.9
Delay disc. indifference point, 4s delay0.20.20.6-0.1-0.30.20.7-0.4-0.40.4-0.20.60.6
Delay disc. indifference point, 8s delay0.61.04.32.11.2-0.8-0.6-0.00.00.0-0.41.31.1
Indifference point function ln k0.10.41.2-1.1-0.3-0.10.60.50.2-0.20.9-0.9-0.7
Indifference point function log k0.10.41.2-1.1-0.3-0.10.60.50.2-0.20.9-0.9-0.7
Patch foraging total patch changes 0 sec0.72.24.82.22.1-1.9-1.61.21.4-1.41.00.1-0.3
Patch foraging total patch changes 12 sec0.30.52.41.50.7-0.4-0.4-0.10.10.0-0.11.10.6
Patch foraging total patch changes 18 sec0.61.45.92.41.2-0.7-0.8-0.20.00.1-0.71.81.3
Patch foraging total patch changes 24 sec0.41.54.91.80.40.2-0.1-0.9-0.60.7-1.22.21.8
Patch foraging total patch changes 6 sec1.52.57.42.72.2-2.0-1.71.11.3-1.20.80.50.1
Patch foraging time to switch 0 sec0.10.52.1-1.5-0.90.60.9-0.0-0.10.30.3-0.7-0.5
Patch foraging water rate 0 sec0.10.52.11.41.0-0.8-1.00.40.5-0.60.20.20.0
Patch foraging water rate 12 sec0.10.51.71.31.1-0.9-0.80.30.5-0.6-0.00.30.3
Patch foraging water rate 18 sec0.40.91.50.81.2-1.2-1.00.91.0-1.01.0-0.7-0.7
Patch foraging water rate 24 sec1.31.94.22.11.9-1.9-1.41.31.2-1.21.0-0.1-0.4
Patch foraging water rate 6 sec0.71.01.41.10.8-1.2-1.11.10.9-1.10.6-0.9-1.2
Seeking ratio, delayed vs. immediate footshock0.00.00.10.1-0.30.10.20.1-0.10.1-0.1-0.1-0.1
Distance traveled before self-admin1.22.56.8-0.80.1-0.6-1.01.41.5-1.51.9-2.5-2.6
Distance traveled after self-admin1.52.65.90.60.9-1.2-1.71.61.8-1.71.4-2.1-2.4
Extensor digitorum longus weight0.20.82.91.71.1-0.9-1.10.50.9-0.90.50.2-0.0
Bone: elastic displacement0.10.10.2-0.2-0.10.20.4-0.2-0.00.00.40.30.3
Bone: elastic work2.02.74.81.01.6-1.6-1.41.71.8-1.82.2-1.4-1.5
Bone: endosteal estimation0.82.06.32.52.1-2.0-1.51.20.8-0.60.60.70.3
Bone: endosteal perimeter1.74.19.03.02.9-3.0-2.02.41.2-1.31.20.2-0.1
Epididymis fat weight3.015.138.06.25.9-5.1-4.03.22.9-2.92.51.10.6
Delta time in closed arm before/after self-admin0.90.91.8-0.00.7-0.6-1.30.91.0-0.80.8-1.2-1.3
Delta time in open arm before/after self-admin0.50.62.01.00.3-0.10.0-0.6-0.50.4-0.91.31.4
Diff in mean of infusions in LGA sessions0.71.24.3-2.1-1.21.21.6-0.8-1.00.7-0.10.20.5
Delay discount exponential model param0.30.51.4-1.0-0.30.1-0.00.40.3-0.40.7-1.2-1.0
Extinction: sum of active levers before priming1.21.93.5-0.1-0.81.11.0-1.5-1.41.5-1.81.91.6
Active lever presses in extinction session 60.20.20.90.90.5-0.4-0.70.10.1-0.0-0.50.40.2
Bone: final force1.11.83.61.81.9-1.9-1.51.50.9-0.90.9-0.0-0.4
Bone: final moment1.42.24.62.12.1-2.1-1.71.61.1-1.11.1-0.0-0.4
Food consumed during 24 hour testing period0.20.41.5-0.20.2-0.70.40.70.5-0.51.2-0.7-0.6
Glucose2.23.44.21.82.0-2.0-2.02.01.9-2.01.7-1.4-1.5
Heart weight1.42.24.51.52.1-1.9-1.11.61.3-1.41.9-0.4-0.4
Delay discount hyperbolic model param0.20.30.8-0.9-0.40.20.00.30.2-0.20.4-0.9-0.8
Intermittent access intake day 1-15 change0.21.23.11.81.7-1.4-1.20.80.8-0.90.70.0-0.0
Intermittent access intake escalation0.21.13.11.81.7-1.3-1.10.60.8-0.90.60.10.1
Intermittent access intake escalation 20.30.61.81.31.2-0.9-0.90.40.6-0.60.30.10.2
Intermitt. access day 1 inactive lever presses0.11.34.62.11.2-0.7-0.7-0.3-0.40.2-0.91.71.5
Intermitt. access day 15 inactive lever presses0.00.20.7-0.00.30.00.2-0.3-0.50.5-0.10.60.9
Intermitt. access escalation Index0.10.40.70.80.3-0.5-0.80.60.8-0.80.3-0.6-0.8
Intermittent access day 1 total infusions0.10.41.30.60.20.00.2-0.5-0.60.6-0.61.10.9
Intermittent access day 15 total infusions0.10.30.90.90.9-0.5-0.2-0.1-0.10.00.10.80.8
Intermittent access terminal intake (last 3 days)0.10.20.50.70.6-0.3-0.2-0.0-0.0-0.0-0.00.50.5
Intermittent access total infusions0.30.41.21.10.6-0.3-0.2-0.3-0.30.3-0.41.00.9
Intermittent access day 1 locomotion0.30.61.10.10.6-0.8-0.50.90.7-0.81.1-0.8-0.8
Intermittent access day 15 total locomotion0.31.33.11.51.8-1.5-1.41.00.9-0.90.8-0.1-0.2
Intermittent access total locomotion1.01.21.50.71.2-1.2-1.11.21.1-1.11.2-1.0-1.0
Intermittent access standard deviation0.10.41.11.00.8-0.4-0.3-0.3-0.30.3-0.51.00.9
Left kidney weight2.016.018.93.74.2-4.2-4.04.24.3-4.34.3-3.1-3.5
Right kidney weight2.718.824.23.94.8-4.8-4.24.54.7-4.74.9-3.1-3.4
Cocaine induced anxiety0.30.83.2-1.8-1.41.00.6-0.3-0.20.2-0.0-1.0-0.9
Post-drug Anxiety0.00.00.00.1-0.20.1-0.1-0.10.0-0.0-0.2-0.1-0.1
Baseline Anxiety0.71.14.62.21.0-0.7-0.4-0.2-0.30.3-0.71.61.3
Tail length0.10.51.90.60.9-0.9-0.00.60.6-0.71.4-0.1-0.0
Length with tail1.14.99.23.02.9-2.6-2.22.12.2-2.22.3-0.5-0.9
Length without tail1.78.825.95.14.1-3.5-3.62.32.6-2.51.60.3-0.5
Times rat made contact with spout1.11.33.31.81.3-1.2-1.11.11.1-1.10.9-0.3-0.6
Lifetime Intake0.40.51.41.20.7-0.3-0.1-0.3-0.30.3-0.41.21.0
Liver weight, left2.54.410.93.32.9-2.8-2.42.01.8-1.61.20.2-0.1
Liver weight, right7.513.121.04.64.4-4.3-4.13.73.6-3.52.9-1.7-2.2
Locomotor activity1.52.33.30.91.4-1.7-1.51.81.7-1.61.6-1.4-1.5
Locomotor testing distance1.74.15.80.81.6-2.0-1.82.42.2-2.12.2-2.3-2.3
Locomotor testing rearing0.62.23.10.91.4-1.6-1.41.81.5-1.51.7-1.4-1.3
Locomotion in novel chamber1.72.34.6-0.00.6-1.0-0.81.61.6-1.61.9-2.1-2.2
Locomotion in novel chamber post-restriction0.20.61.9-1.4-1.21.11.0-0.6-0.40.40.1-0.4-0.2
Fecal boli incidents, locomotor time 10.10.20.40.3-0.30.40.4-0.5-0.50.5-0.50.60.6
Change in fecal boli incidents, locomotor task0.20.21.5-1.2-0.20.30.5-0.1-0.00.00.5-0.3-0.1
Time >=10cm from walls, locomotor time 10.40.51.2-0.5-1.11.10.7-0.8-0.50.6-0.70.1-0.0
Bouts of movement, locomotor time 10.81.02.91.70.9-0.3-0.3-0.5-0.50.5-0.91.71.5
Total resting periods, locomotor time 10.70.82.21.50.9-0.5-0.5-0.3-0.30.4-0.81.51.3
Rest time, locomotor task time 10.20.40.80.40.9-0.8-0.70.60.6-0.60.5-0.2-0.2
Distance moved, locomotor task time 10.00.00.00.2-0.10.10.0-0.1-0.00.1-0.1-0.1-0.2
Vertical activity count, locomotor time 10.10.92.3-1.4-0.50.00.60.50.4-0.61.3-1.5-1.3
Time >=10cm from walls, locomotor time 20.10.41.81.30.8-0.4-0.90.10.2-0.2-0.40.40.3
Bouts of movement, locomotor time 20.10.50.9-0.8-1.00.80.9-0.6-0.70.7-0.20.20.3
Total resting periods, locomotor time 20.10.20.5-0.4-0.60.60.7-0.4-0.50.5-0.20.30.3
Rest time, locomotor task time 20.20.30.60.1-0.1-0.3-0.00.60.5-0.50.8-0.8-0.7
Distance moved, locomotor task time 20.40.51.20.50.10.30.3-0.8-0.70.7-0.81.11.1
Vertical activity count, locomotor time 20.00.10.40.60.5-0.4-0.30.1-0.1-0.20.10.10.1
Light reinforcement 10.31.12.0-1.4-1.31.21.3-0.9-1.21.1-0.90.40.5
Light reinforcement 20.41.02.4-1.5-1.31.11.3-0.6-1.10.9-0.50.00.1
Bone: marrow area0.92.16.52.62.2-2.0-1.51.20.8-0.70.60.60.3
Bone: maximum diameter2.65.315.63.93.4-3.2-2.22.21.3-1.41.11.00.5
Bone: maximum force0.61.22.91.41.6-1.7-1.01.40.7-0.61.0-0.0-0.3
Bone: maximum moment0.81.53.21.71.8-1.8-1.21.40.8-0.81.10.0-0.2
Mean time between licks in bursts0.10.51.20.1-0.20.30.8-0.6-0.70.7-0.51.11.1
Mean num. licks in bursts0.82.23.70.51.0-1.0-1.31.31.8-1.81.8-1.9-1.9
Cd content in liver1.61.85.3-1.10.2-0.6-0.61.31.2-1.21.6-2.3-2.1
Co content in liver0.50.51.8-0.8-0.70.7-0.3-0.10.5-0.50.3-1.3-1.2
Cu content in liver0.00.00.1-0.0-0.20.2-0.10.10.1-0.20.0-0.4-0.4
Fe content in liver0.30.31.10.90.6-0.2-0.1-0.3-0.10.1-0.11.01.0
K content in liver0.50.51.1-0.4-0.91.10.5-1.0-0.50.5-0.80.40.3
Mg content in liver0.30.30.5-0.1-0.50.70.5-0.7-0.60.5-0.70.60.6
Mn content in liver0.00.10.2-0.5-0.30.10.2-0.0-0.10.1-0.1-0.2-0.2
Na content in liver1.61.82.5-1.3-1.61.21.5-1.2-1.61.5-1.21.01.1
Rb content in liver2.12.43.7-1.2-1.51.71.7-1.9-1.51.5-1.51.41.4
Se content in liver1.31.52.3-1.4-1.51.41.5-1.2-1.31.3-1.00.60.7
Sr content in liver0.80.72.4-1.6-1.20.90.9-0.4-0.40.4-0.1-0.9-0.6
Zn content in liver0.20.20.5-0.6-0.70.70.1-0.30.1-0.2-0.0-0.7-0.7
Bone: minimum diameter1.63.27.42.72.6-2.5-1.61.81.1-1.21.40.50.3
Time in familiar zone, hab. session 10.50.51.6-1.0-0.4-0.10.20.50.4-0.40.7-1.3-1.1
Time in novel zone, hab. session 10.60.62.21.10.6-0.30.0-0.2-0.50.5-0.61.51.3
Total zone transitions, hab. session 11.42.03.01.31.6-1.7-1.41.51.5-1.51.6-0.8-1.0
Total locomotion distance, hab. session 10.00.00.20.20.1-0.20.20.0-0.10.10.10.40.3
Locomotion velocity, hab. session 10.00.00.10.00.1-0.10.2-0.1-0.10.10.10.30.3
Time in familiar zone, hab. session 20.91.02.81.71.4-1.1-0.70.20.1-0.1-0.31.41.3
Time in novel zone, hab. session 20.60.72.2-1.1-0.70.40.30.30.4-0.40.8-1.5-1.4
Total zone transitions, hab. session 21.92.53.61.41.9-1.9-1.51.61.7-1.71.9-0.8-0.9
Total locomotion distance, hab. session 20.91.21.91.21.4-1.3-1.01.11.2-1.21.3-0.4-0.5
Locomotion velocity, hab. session 20.60.81.10.91.1-1.1-0.80.91.0-1.01.0-0.4-0.5
Novel to familiar place preference ratio0.20.30.5-0.0-0.30.40.2-0.5-0.60.6-0.70.70.7
Novelty place preference0.20.20.50.1-0.10.20.1-0.4-0.50.5-0.70.70.7
Time in novel zone, NPP test0.30.31.10.50.20.00.0-0.4-0.50.5-0.61.01.0
Total zone transitions, NPP test1.21.73.31.81.8-1.6-1.51.21.3-1.31.1-0.1-0.3
Total locomotion distance, NPP test0.60.91.81.41.3-1.2-0.80.80.9-0.90.80.20.1
Locomotion velocity, NPP test0.50.71.10.91.0-1.0-0.70.80.9-0.90.8-0.2-0.3
Intraocular pressure1.11.74.72.12.2-1.8-1.10.90.8-0.70.90.80.6
Delta distance traveled before/after self-admin0.70.82.51.61.3-1.0-1.30.70.6-0.6-0.00.0-0.2
Delta ambulatory time before/after self-admin0.50.83.51.91.1-0.7-0.90.10.1-0.0-0.70.90.7
Parametrial fat weight4.09.429.55.44.6-4.1-3.12.11.9-1.91.31.51.0
Pavlov. Cond. lever latency0.20.30.70.90.8-0.8-0.40.50.4-0.30.20.30.2
Pavlov. Cond. magazine entry latency0.20.30.70.80.6-0.3-0.80.20.5-0.60.30.0-0.1
Pavlov. Cond. change in total contacts0.20.20.40.00.1-0.1-0.40.40.5-0.50.5-0.6-0.6
Pavlov. Cond. index score0.30.30.70.50.5-0.3-0.80.30.7-0.80.6-0.5-0.5
Pavlov. Cond. latency score0.20.20.50.40.4-0.2-0.70.30.6-0.70.5-0.5-0.5
Pavlov. Cond. lever contacts0.30.40.9-1.0-0.80.80.5-0.6-0.60.5-0.4-0.10.1
Pavlov. Cond. magazine entry number1.21.62.4-1.4-1.31.01.6-1.0-1.51.5-1.30.80.9
Pavlov. Cond. intertrial magazine entries0.10.10.30.20.4-0.6-0.00.30.3-0.30.5-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.50.3-0.1-0.70.10.5-0.60.3-0.3-0.4
Pavlov. Cond. response bias0.10.10.20.00.10.1-0.40.00.3-0.40.3-0.4-0.4
Pavlov. Cond. lever latency1.72.45.9-0.10.6-0.8-1.21.41.7-1.71.6-2.4-2.3
Pavlov. Cond. magazine entry latency0.50.73.51.91.0-0.6-0.80.10.3-0.3-0.11.00.7
Pavlov. Cond. change in total contacts0.71.75.10.5-0.10.31.1-1.2-1.21.2-1.02.32.2
Pavlov. Cond. index score0.71.14.11.10.3-0.10.4-0.6-0.90.9-0.82.01.8
Pavlov. Cond. latency score0.71.13.91.30.5-0.10.2-0.6-0.70.8-0.82.01.7
Pavlov. Cond. lever contacts0.91.33.60.2-0.40.41.0-0.9-1.21.2-1.01.91.8
Pavlov. Cond. magazine entry number0.40.62.6-1.6-0.80.50.50.1-0.10.00.1-1.1-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.10.4-0.6-0.20.7-0.0-0.00.3-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.60.93.31.20.4-0.20.2-0.5-0.70.7-0.71.81.6
Pavlov. Cond. response bias0.91.24.00.7-0.00.20.8-0.9-1.01.1-0.92.01.8
Time in closed arm before self-admin0.10.20.9-0.9-0.40.10.7-0.00.0-0.20.4-0.30.1
Time in closed arm after self-admin0.30.41.7-1.3-0.40.20.30.20.2-0.20.7-0.8-0.6
Time in open arm before self-admin0.50.61.2-0.4-1.11.10.6-0.7-0.80.9-1.00.40.1
Time in open arm after self-admin1.21.33.20.9-0.40.60.3-1.1-1.11.1-1.81.71.4
Bone: periosteal estimation2.45.814.33.83.5-3.4-2.42.41.7-1.61.70.50.0
Bone: periosteal perimeter3.67.017.04.13.8-3.8-2.72.81.8-1.91.60.4-0.1
Bone: post-yield work0.71.22.50.1-0.40.40.6-0.8-1.31.3-1.61.61.6
Progressive ratio test 1 active lever presses0.30.51.70.70.5-0.20.1-0.6-0.50.4-0.51.31.2
Progressive ratio test 1 breakpoint0.30.51.70.60.4-0.20.2-0.6-0.50.4-0.51.31.2
Progressive ratio test 1 inactive lever presses0.51.33.61.20.40.10.2-0.9-1.00.9-1.21.91.8
Progressive ratio test 2 active lever presses0.50.82.51.61.4-0.8-0.70.00.1-0.1-0.11.01.0
Progressive ratio test 2 breakpoint0.70.82.91.71.5-0.9-0.90.10.2-0.2-0.10.90.9
Progressive ratio test 2 inactive lever presses0.20.82.21.50.9-0.4-0.3-0.3-0.40.5-0.61.41.4
Incentive Sensitization - Responses0.30.72.91.71.3-0.7-0.90.10.2-0.0-0.30.80.7
Incentive Sensitization - Breakpoint0.30.62.71.61.2-0.6-0.90.10.2-0.0-0.30.70.7
Sum of active levers in priming session hrs 5-60.90.81.6-0.4-0.91.00.6-0.9-1.01.1-1.30.90.7
Progressive ratio0.41.21.6-1.3-1.21.01.3-1.0-1.11.1-0.90.81.1
Food seeking constrained by brief footshock1.62.03.5-0.3-1.01.11.4-1.5-1.61.6-1.51.91.8
Seeking ratio, punishment vs. effort0.10.31.21.10.8-0.6-0.60.40.4-0.30.20.0-0.3
Retroperitoneal fat weight4.721.259.07.77.0-5.9-5.23.53.3-3.32.41.40.8
Reaction time number correct0.20.83.61.91.2-0.9-0.90.30.5-0.4-0.00.70.6
Reaction time mean minus median0.00.20.40.60.5-0.5-0.50.50.2-0.20.00.10.1
Reaction time mean minus median AUC0.10.81.30.81.0-1.0-1.11.10.9-0.90.8-0.7-0.7
Reaction time num false alarms0.00.10.20.10.10.2-0.1-0.4-0.20.3-0.20.40.4
Reaction time num false alarms AUC0.00.00.10.00.10.2-0.2-0.3-0.00.10.00.10.1
Reaction time trials correct on left0.20.83.61.91.2-0.9-0.90.30.5-0.4-0.00.70.6
Reaction time trials on left0.20.83.61.91.2-1.0-0.90.40.5-0.50.00.70.6
Reaction time mean0.20.51.1-0.10.4-0.5-0.70.90.6-0.60.6-1.0-1.0
Reaction time mean AUC0.10.20.7-0.6-0.1-0.1-0.20.50.2-0.20.3-0.8-0.7
Median of all reaction times0.50.71.9-0.30.3-0.5-0.71.00.7-0.70.8-1.4-1.3
Reaction time omissions0.10.10.4-0.10.5-0.6-0.10.4-0.10.10.30.20.2
Reaction time false alarm rate0.20.31.1-1.0-0.60.80.5-0.6-0.50.5-0.20.00.1
Reaction time premature initiation rate1.32.03.11.01.0-1.0-1.71.41.7-1.71.3-1.6-1.8
Reaction time premature initiations1.13.45.22.21.8-1.7-2.31.72.1-2.11.4-1.3-1.6
Std. dev. reaction times0.30.91.51.01.2-1.2-1.11.10.8-0.80.7-0.3-0.4
Reaction time trials completed0.20.83.61.91.2-1.0-0.90.40.5-0.50.00.70.6
Reaction time trials AUC0.20.93.71.91.2-1.0-0.90.40.5-0.50.10.70.6
Run reversals in cocaine runway, females1.31.52.21.51.2-1.3-1.31.31.2-1.31.0-0.9-1.0
Run reversals in cocaine runway, males1.11.31.7-1.2-1.21.21.1-1.1-1.21.3-1.10.80.9
Latency to leave start box in cocaine runway0.20.30.9-0.9-0.90.70.8-0.3-0.50.4-0.1-0.2-0.2
Latency to leave start box in cocaine runway, F0.40.51.7-1.3-1.00.70.8-0.2-0.20.30.2-0.6-0.5
Latency to leave start box in cocaine runway, M0.10.10.20.40.2-0.1-0.10.0-0.20.1-0.10.30.3
Std. dev. time between licks in bursts1.12.14.1-0.1-0.80.81.5-1.4-1.61.6-1.52.02.0
Total sessions with >9 infusions0.80.92.61.61.5-1.3-0.90.70.7-0.60.80.2-0.0
Short access day 1 total inactive lever presses0.40.83.31.80.9-0.4-0.8-0.2-0.20.1-0.91.10.9
Short access day 10 total inactive lever presses0.10.61.31.01.1-0.9-1.10.70.5-0.60.2-0.0-0.0
Short access day 1 total infusions0.10.20.90.90.6-0.4-0.50.00.1-0.0-0.10.40.3
Short access day 10 total infusions0.30.50.9-0.4-0.40.50.8-0.7-0.80.8-0.50.90.9
Short access total infusions0.10.20.70.70.3-0.20.1-0.3-0.30.3-0.30.80.6
Short access day 1 locomotion0.20.40.90.90.4-0.1-0.2-0.3-0.40.4-0.61.00.8
Short access day 10 total locomotion0.72.83.80.71.4-1.7-1.71.91.7-1.71.7-1.7-1.9
Short access total locomotion0.81.31.80.71.2-1.2-1.11.21.2-1.11.3-1.0-1.2
One hour access (0.3 mA shock)2.93.49.61.60.10.50.4-1.6-1.71.7-2.43.12.7
Compulsive drug intake1.11.63.80.9-0.50.70.5-1.2-1.21.2-2.01.91.6
One hour access (shock baseline)0.00.10.40.40.7-0.5-0.30.10.1-0.00.20.40.4
Social response proportion3.74.76.11.92.2-2.2-2.52.32.3-2.32.0-1.9-2.1
Social responses1.62.16.92.62.2-1.6-1.90.91.0-1.00.50.60.2
Social time1.21.83.61.61.6-1.2-1.91.21.4-1.50.9-0.8-1.0
Soleus weight4.914.318.74.34.2-3.9-4.33.74.1-4.13.4-2.3-2.8
Bone: stiffness0.10.20.90.10.5-0.90.00.9-0.00.10.6-0.1-0.1
Tibialis anterior weight0.20.71.50.0-0.70.90.5-1.2-0.70.7-0.91.11.1
Time to tail flick, vehicle, before self-admin0.30.41.31.10.7-0.7-0.80.60.6-0.60.2-0.2-0.3
Time to tail flick, vehicle, after self-admin0.10.20.30.5-0.60.50.5-0.4-0.40.3-0.50.30.2
Time to tail flick, test, before self-admin1.21.42.4-0.10.7-0.9-1.11.31.2-1.21.2-1.5-1.6
Time to tail flick, test, after self-admin0.30.31.01.00.2-0.2-0.1-0.3-0.30.4-0.60.90.7
Delta time to tail flick, vehicle, before/after SA0.80.81.3-0.1-0.70.81.1-1.0-0.90.9-0.81.11.1
Delta time to tail flick, test, before/after SA0.20.30.70.7-0.10.20.3-0.5-0.40.5-0.60.80.7
Tibia length1.85.17.62.02.5-2.8-2.32.72.3-2.22.3-1.5-1.8
Ambulatory time before self-admin1.13.47.1-0.30.8-1.2-1.41.81.9-1.92.2-2.6-2.7
Ambulatory time after self-admin1.93.15.21.31.3-1.5-2.11.81.9-1.81.2-2.0-2.3
Bone: tissue strength0.30.40.7-0.8-0.60.70.8-0.7-0.60.6-0.10.30.4
Total heroin consumption0.70.82.41.51.5-1.2-0.80.40.3-0.50.40.70.6
Bone: trabecular number0.20.31.11.10.4-0.2-0.1-0.2-0.30.3-0.31.10.8
Bone: trabecular spacing0.20.30.6-0.8-0.60.60.5-0.5-0.50.5-0.40.30.4
Bone: trabecular thickness2.12.910.73.32.4-2.0-2.01.11.1-1.10.40.80.4
Bone: trabecular tissue density0.10.20.5-0.6-0.1-0.40.00.70.1-0.10.3-0.6-0.5
Water consumed over 24 hours0.81.62.50.91.2-1.5-0.81.61.3-1.31.5-1.1-1.3
Number of responses in last shaping day0.00.00.10.00.2-0.00.1-0.20.0-0.00.40.10.3