Hub : Traits : Body weight : ← : →

chr10:81,874,092-84,687,108

Trait: Body weight

Best TWAS P=5.72e-09 · Best GWAS P=8.59e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Cdk12	alternative polyA	ENSRNOT00000114817	0.02	908	0.02	4.4e-03	-5.2	2.04e-07	0.45	FALSE
Adipose	Cdk12	gene expression	ENSRNOG00000006000	0.16	75	0.29	1.5e-32	5.2	1.97e-07	0.56	FALSE
Adipose	Pcgf2	gene expression	ENSRNOG00000012705	0.02	1	0.02	1.9e-03	-5.18	2.19e-07	0.04	FALSE
Adipose	Stard3	gene expression	ENSRNOG00000042044	0.02	1	0.01	1.4e-02	-5.26	1.46e-07	0.04	FALSE
Adipose	Mllt6	gene expression	ENSRNOG00000053285	0.02	1	0.04	5.7e-05	5.18	2.27e-07	0.04	FALSE
Adipose	Cdk12	isoform ratio	ENSRNOT00000114817	0.03	908	0.04	8.8e-05	-5.2	1.96e-07	0.54	FALSE
Adipose	Cdk12	intron excision ratio	chr10:83253382:83266506	0.02	908	0.01	1.8e-02	5.35	8.74e-08	0.37	FALSE
Adipose	Cdk12	intron excision ratio	chr10:83271000:83279092	0.02	908	0.02	2.6e-03	-5.49	3.93e-08	0.48	FALSE
Adipose	ENSRNOG00000028430	intron excision ratio	chr10:83271000:83279092	0.02	907	0.02	2.8e-03	-5.51	3.67e-08	0.49	FALSE
Adipose	Lasp1	mRNA stability	ENSRNOG00000004132	0.03	1	0.04	5.4e-05	5.17	2.36e-07	0.11	FALSE
Adipose	Rpl19	mRNA stability	ENSRNOG00000004741	0.07	1	0.07	2.0e-08	5.18	2.19e-07	0.6	FALSE
Adipose	Fbxl20	mRNA stability	ENSRNOG00000005081	0.04	979	0.03	1.7e-04	5.27	1.39e-07	0.48	FALSE
Adipose	Cdk12	mRNA stability	ENSRNOG00000006000	0.05	908	0.07	2.2e-08	5.19	2.08e-07	0.54	FALSE
BLA	Cacnb1	gene expression	ENSRNOG00000004518	0.13	971	0.01	7.2e-02	5.21	1.91e-07	0.32	FALSE
BLA	Zpbp2	intron excision ratio	chr10:83560463:83563463	0.06	1117	0.02	2.5e-02	-5.46	4.85e-08	0.38	FALSE
BLA	Srcin1	intron excision ratio	chr10:82536884:82546225	0.06	1	0.04	4.6e-03	5.11	3.17e-07	0.04	FALSE
BLA	Msl1	mRNA stability	ENSRNOG00000009643	0.25	1470	0.12	4.1e-07	-5.25	1.54e-07	0.45	FALSE
Brain	Lasp1	alternative polyA	ENSRNOT00000005522	0.08	17	0.07	2.5e-07	-5.21	1.85e-07	0.6	FALSE
Brain	Lasp1	alternative polyA	ENSRNOT00000102880	0.09	16	0.07	3.8e-07	5.22	1.80e-07	0.61	FALSE
Brain	Cdk12	alternative polyA	ENSRNOT00000008256	0.04	908	0.03	9.9e-04	-5.5	3.76e-08	0.55	FALSE
Brain	Cacnb1	gene expression	ENSRNOG00000004518	0.04	971	0.04	2.0e-04	5.1	3.47e-07	0.5	FALSE
Brain	Stac2	gene expression	ENSRNOG00000004805	0.07	937	0.08	6.2e-08	-5.18	2.22e-07	0.59	FALSE
Brain	Igfbp4	gene expression	ENSRNOG00000010635	0.23	1	0.17	3.3e-15	5.24	1.59e-07	0.73	TRUE
Brain	Cisd3	gene expression	ENSRNOG00000036894	0.08	1	0.08	1.3e-07	-5.21	1.94e-07	0.66	FALSE
Brain	Stard3	gene expression	ENSRNOG00000042044	0.06	887	0.07	4.1e-07	-5.38	7.27e-08	0.56	FALSE
Brain	Cacnb1	isoform ratio	ENSRNOT00000082974	0.03	1	0.02	8.5e-03	5.18	2.16e-07	0.04	FALSE
Brain	Cdk12	isoform ratio	ENSRNOT00000008256	0.04	1	0.04	5.6e-05	-5.14	2.68e-07	0.22	FALSE
Brain	Cdk12	isoform ratio	ENSRNOT00000082668	0.04	908	0.03	1.6e-03	5.17	2.28e-07	0.56	FALSE
Brain	Cacnb1	intron excision ratio	chr10:83007534:83008770	0.03	971	0.02	3.5e-03	-5.1	3.36e-07	0.52	FALSE
Brain	Cacnb1	intron excision ratio	chr10:83008403:83008770	0.04	971	0.02	2.4e-03	5.11	3.15e-07	0.54	FALSE
Brain	Rpl19	intron excision ratio	chr10:83022773:83023579	0.1	971	0.04	1.1e-04	-5.27	1.39e-07	0.6	FALSE
Brain	Cdk12	intron excision ratio	chr10:83271000:83276800	0.08	1	0.05	4.5e-05	5.22	1.77e-07	0.12	FALSE
Brain	Cdk12	intron excision ratio	chr10:83271000:83279092	0.09	1	0.12	1.7e-11	-5.18	2.16e-07	0.58	FALSE
Brain	Srcin1	intron excision ratio	chr10:82536884:82546225	0.07	28	0.07	8.4e-07	5.24	1.60e-07	0.69	FALSE
Brain	ENSRNOG00000028430	intron excision ratio	chr10:83271000:83276800	0.08	1	0.05	4.5e-05	5.22	1.77e-07	0.12	FALSE
Brain	ENSRNOG00000028430	intron excision ratio	chr10:83271000:83279092	0.09	1	0.12	1.7e-11	-5.18	2.16e-07	0.58	FALSE
Brain	Mllt6	intron excision ratio	chr10:82666187:82667041	0.03	1	0.01	2.1e-02	5.27	1.36e-07	0.04	FALSE
Brain	Lasp1	mRNA stability	ENSRNOG00000004132	0.07	1	0.06	2.6e-06	5.21	1.94e-07	0.5	FALSE
Brain	Cacnb1	mRNA stability	ENSRNOG00000004518	0.08	971	0.08	1.2e-07	-5.19	2.12e-07	0.61	FALSE
Brain	Fbxl20	mRNA stability	ENSRNOG00000005081	0.05	979	0.06	6.7e-06	-5.41	6.27e-08	0.59	FALSE
Brain	Stard3	mRNA stability	ENSRNOG00000042044	0.08	887	0.1	3.9e-09	-5.35	8.72e-08	0.63	FALSE
LHb	ENSRNOG00000028430	mRNA stability	ENSRNOG00000028430	0.37	1	0.11	1.7e-03	-5.19	2.09e-07	0.06	FALSE
Liver	Fbxl20	alternative TSS	ENSRNOT00000067317	0.03	979	0.01	1.2e-02	5.09	3.55e-07	0.43	FALSE
Liver	Cdk12	isoform ratio	ENSRNOT00000008256	0.03	1	0.03	5.6e-04	-5.27	1.37e-07	0.14	FALSE
Liver	Cdk12	intron excision ratio	chr10:83271000:83276800	0.02	908	0.01	1.8e-02	5.42	5.89e-08	0.38	FALSE
Liver	Zpbp2	intron excision ratio	chr10:83566539:83567063	0.03	1	0.02	5.7e-03	5.22	1.75e-07	0.04	FALSE
Liver	ENSRNOG00000028430	intron excision ratio	chr10:83271000:83276800	0.02	907	0.01	1.7e-02	5.42	6.10e-08	0.38	FALSE
Liver	Zpbp2	mRNA stability	ENSRNOG00000007255	0.06	1	0.01	2.3e-02	5.31	1.07e-07	0.08	FALSE
Liver	Srcin1	mRNA stability	ENSRNOG00000011475	0.02	1	0.02	2.0e-03	5.2	1.94e-07	0.05	FALSE
Liver	ENSRNOG00000028430	mRNA stability	ENSRNOG00000028430	0.07	16	0.08	1.3e-09	-5.56	2.72e-08	0.57	FALSE
Liver	Ormdl3	mRNA stability	ENSRNOG00000030445	0.18	1	0.22	1.4e-24	5.31	1.07e-07	0.76	FALSE
Liver	Stard3	mRNA stability	ENSRNOG00000042044	0.02	887	0.02	5.8e-03	-5.12	2.98e-07	0.43	FALSE
NAcc	Cdk12	alternative polyA	ENSRNOT00000082668	0.05	51	0.02	1.2e-02	5.82	5.72e-09	0.48	TRUE
NAcc	Cdk12	alternative polyA	ENSRNOT00000082668	0.04	908	0.03	2.3e-03	5.55	2.79e-08	0.48	FALSE
NAcc	Cdk12	alternative polyA	ENSRNOT00000105342	0.04	908	0.03	2.9e-03	-5.55	2.89e-08	0.48	FALSE
NAcc	Ppp1r1b	gene expression	ENSRNOG00000028404	0.03	891	0.01	9.8e-02	5.45	4.91e-08	0.4	FALSE
NAcc	Arl5c	gene expression	ENSRNOG00000036880	0.05	1	0.02	8.1e-03	5.21	1.94e-07	0.05	FALSE
NAcc	Tcap	gene expression	ENSRNOG00000068106	0.03	1	0.01	7.3e-02	5.21	1.94e-07	0.04	FALSE
NAcc	ENSRNOG00000070737	gene expression	ENSRNOG00000070737	0.06	1012	0.05	2.0e-04	-5.14	2.75e-07	0.55	FALSE
NAcc	ENSRNOG00000070737	isoform ratio	ENSRNOT00000094296	0.05	1012	0.03	1.3e-03	-5.09	3.55e-07	0.5	FALSE
NAcc	ENSRNOG00000070737	isoform ratio	ENSRNOT00000101608	0.04	1012	0.04	1.2e-03	5.1	3.39e-07	0.5	FALSE
NAcc	Cdk12	intron excision ratio	chr10:83271000:83279092	0.04	908	0.03	5.4e-03	-5.14	2.74e-07	0.39	FALSE
NAcc	ENSRNOG00000028430	intron excision ratio	chr10:83271000:83279092	0.04	907	0.03	4.8e-03	-5.1	3.40e-07	0.38	FALSE
OFC	Msl1	intron excision ratio	chr10:83760232:83762620	0.15	4	0.11	1.1e-03	-5.23	1.74e-07	0.31	FALSE
OFC	Srcin1	intron excision ratio	chr10:82530385:82530945	0.17	1	0.1	2.8e-03	-5.27	1.38e-07	0.08	FALSE
OFC	Srcin1	intron excision ratio	chr10:82530709:82530945	0.19	1	0.11	1.8e-03	5.27	1.38e-07	0.09	FALSE
PL	Stac2	alternative TSS	ENSRNOT00000066855	0.04	937	0.03	3.1e-03	5.17	2.36e-07	0.45	FALSE
PL	Stac2	alternative TSS	ENSRNOT00000091978	0.04	937	0.03	3.1e-03	-5.17	2.33e-07	0.46	FALSE
PL	Cacnb1	gene expression	ENSRNOG00000004518	0.04	971	0.03	4.1e-03	5.12	3.12e-07	0.5	FALSE
PL	Rpl19	gene expression	ENSRNOG00000004741	0.04	971	0.01	3.3e-02	-5.12	3.02e-07	0.47	FALSE
PL	Stac2	gene expression	ENSRNOG00000004805	0.15	937	0.13	8.5e-10	-5.22	1.82e-07	0.58	FALSE
PL	Srcin1	gene expression	ENSRNOG00000011475	0.05	1	0.03	2.5e-03	5.21	1.94e-07	0.05	FALSE
PL	Ppp1r1b	gene expression	ENSRNOG00000028404	0.15	891	0.03	2.3e-03	5.55	2.81e-08	0.52	TRUE
PL	Ormdl3	gene expression	ENSRNOG00000030445	0.15	1118	0.1	1.1e-07	-5.57	2.55e-08	0.58	FALSE
PL	Arl5c	gene expression	ENSRNOG00000036880	0.05	1013	0.04	7.1e-04	-5.11	3.17e-07	0.48	TRUE
PL	Tcap	gene expression	ENSRNOG00000068106	0.18	39	0.11	9.8e-09	5.23	1.68e-07	0.62	FALSE
PL	Cdk12	isoform ratio	ENSRNOT00000082668	0.03	908	0.01	2.5e-02	5.26	1.46e-07	0.39	FALSE
PL	Rpl19	intron excision ratio	chr10:83018591:83023579	0.16	971	0.15	3.0e-11	5.24	1.56e-07	0.63	FALSE
PL	Rpl19	intron excision ratio	chr10:83022773:83023579	0.07	971	0.04	2.2e-04	-5.26	1.45e-07	0.6	FALSE
PL	Rpl19	mRNA stability	ENSRNOG00000004741	0.05	20	0.04	9.9e-04	5.34	9.53e-08	0.48	TRUE
PL	Thra	mRNA stability	ENSRNOG00000009066	0.05	1	0.03	1.3e-03	5.13	2.91e-07	0.04	FALSE