Hub : Traits : Body weight : ← : →

chr10:81,874,092-84,877,260

Trait: Body weight

Best TWAS P=1.02e-08 · Best GWAS P=8.59e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Cdk12	alternative polyA	XM_039085161.1	0.02	892	0.01	6.9e-03	-5.35	8.92e-08	0.45	FALSE
Adipose	Med1	alternative polyA	XM_006247399.4	0.02	903	0.02	2.9e-03	-5.43	5.59e-08	0.4	FALSE
Adipose	Cdk12	gene expression	Cdk12	0.14	76	0.21	1.2e-22	-5.37	7.89e-08	0.57	FALSE
Adipose	Rpl19	gene expression	Rpl19	0.53	8	0.45	2.1e-54	-5.21	1.93e-07	0.61	FALSE
Adipose	Stard3	gene expression	Stard3	0.02	872	0.02	2.1e-03	-5.18	2.27e-07	0.5	FALSE
Adipose	Wipf2	gene expression	Wipf2	0.03	1	0.03	1.2e-04	-5.28	1.30e-07	0.44	FALSE
Adipose	Cdk12	isoform ratio	XM_039085161.1	0.02	892	0.02	4.2e-03	-5.29	1.21e-07	0.46	FALSE
Adipose	Msl1	isoform ratio	NM_001107048.1	0.03	1	0.01	1.1e-02	-5.19	2.16e-07	0.06	FALSE
Adipose	Med1	intron excision ratio	chr10_83146490_83151683	0.02	903	0.01	3.6e-02	-5.41	6.38e-08	0.38	FALSE
Adipose	Cdk12	mRNA stability	Cdk12	0.05	892	0.06	1.2e-07	5.23	1.69e-07	0.55	FALSE
Adipose	Fbxl20	mRNA stability	Fbxl20	0.05	964	0.07	5.6e-08	5.27	1.36e-07	0.5	FALSE
Adipose	Lasp1	mRNA stability	Lasp1	0.02	1	0.02	1.9e-03	-5.22	1.78e-07	0.04	FALSE
BLA	Fbxl20	intron excision ratio	chr10_83108186_83120368	0.08	1	0.04	4.8e-03	-5.26	1.47e-07	0.05	FALSE
BLA	Srcin1	intron excision ratio	chr10_82536884_82543393	0.05	1	0.01	5.5e-02	5.26	1.47e-07	0.04	FALSE
BLA	Srcin1	intron excision ratio	chr10_82536884_82546225	0.06	1	0.04	2.1e-03	-5.26	1.47e-07	0.05	FALSE
BLA	Zpbp2	intron excision ratio	chr10_83560463_83563463	0.05	1101	0.03	1.3e-02	-5.5	3.74e-08	0.33	FALSE
BLA	Cacnb1	mRNA stability	Cacnb1	0.1	1	0.07	1.9e-04	5.26	1.47e-07	0.23	FALSE
BLA	Msl1	mRNA stability	Msl1	0.15	1454	0.08	3.1e-05	-5.29	1.21e-07	0.44	FALSE
Brain	Fbxl20	alternative TSS	XM_039086778.1	0.04	1	0.03	5.6e-04	5.24	1.59e-07	0.12	FALSE
Brain	Fbxl20	alternative TSS	XM_039086778.1	0.04	1	0.03	6.9e-04	5.24	1.59e-07	0.1	FALSE
Brain	Pcgf2	alternative TSS	XM_008767971.2	0.04	1	0.03	7.4e-04	5.22	1.77e-07	0.05	FALSE
Brain	Epop	gene expression	Epop	0.03	1	0.03	1.5e-03	5.28	1.28e-07	0.06	FALSE
Brain	Igfbp4	gene expression	Igfbp4	0.33	10	0.24	2.5e-22	5.26	1.46e-07	0.73	FALSE
Brain	Ormdl3	gene expression	Ormdl3	0.05	25	0.03	1.0e-03	-5.49	3.96e-08	0.59	FALSE
Brain	Rpl19	gene expression	Rpl19	0.24	956	0.21	1.4e-19	-5.25	1.52e-07	0.63	FALSE
Brain	Stac2	gene expression	Stac2	0.08	1	0.08	6.8e-08	5.27	1.39e-07	0.7	FALSE
Brain	Stard3	gene expression	Stard3	0.05	872	0.05	1.0e-05	-5.35	8.79e-08	0.53	FALSE
Brain	Fbxl20	isoform ratio	XM_039086778.1	0.04	964	0.04	1.5e-04	-5.34	9.32e-08	0.56	FALSE
Brain	Pcgf2	isoform ratio	XM_008767971.2	0.05	1	0.05	2.3e-05	5.22	1.77e-07	0.23	FALSE
Brain	Srcin1	isoform ratio	NM_019378.2	0.38	1	0.37	1.1e-35	-5.26	1.47e-07	0.79	FALSE
Brain	Fbxl20	intron excision ratio	chr10_83120429_83142533	0.03	12	0.03	1.6e-03	-5.3	1.18e-07	0.38	TRUE
Brain	Mllt6	intron excision ratio	chr10_82666271_82667041	0.02	1	0.02	9.4e-03	5.28	1.28e-07	0.05	FALSE
Brain	Rpl19	intron excision ratio	chr10_83022773_83023579	0.11	956	0.04	1.5e-04	-5.2	2.01e-07	0.61	FALSE
Brain	Srcin1	intron excision ratio	chr10_82536884_82546225	0.07	1	0.06	1.1e-06	-5.27	1.39e-07	0.72	FALSE
Brain	Arl5c	mRNA stability	Arl5c	0.08	999	0.04	1.3e-04	-5.22	1.75e-07	0.59	FALSE
Brain	Cacnb1	mRNA stability	Cacnb1	0.13	958	0.09	6.2e-09	-5.23	1.69e-07	0.63	FALSE
Brain	Cisd3	mRNA stability	Cisd3	0.11	1	0.05	1.9e-05	5.28	1.28e-07	0.27	FALSE
Brain	Fbxl20	mRNA stability	Fbxl20	0.05	1	0.06	2.9e-06	5.27	1.39e-07	0.58	FALSE
Brain	Stac2	mRNA stability	Stac2	0.08	923	0.07	2.4e-07	-5.21	1.91e-07	0.6	FALSE
IL	Rapgefl1	gene expression	Rapgefl1	0.24	1	0.22	5.5e-06	5.17	2.29e-07	0.07	TRUE
IL	Stac2	gene expression	Stac2	0.19	1	0.11	1.5e-03	5.17	2.29e-07	0.06	FALSE
LHb	Cwc25	gene expression	Cwc25	0.21	1	0.09	3.1e-03	-5.22	1.83e-07	0.06	FALSE
Liver	Pcgf2	alternative polyA	NM_001105836.2	0.06	1	0.07	1.2e-08	-5.18	2.19e-07	0.64	FALSE
Liver	Pcgf2	alternative polyA	XM_039085606.1	0.06	1	0.07	1.6e-08	5.18	2.19e-07	0.64	FALSE
Liver	Grb7	alternative TSS	NM_053403.2	0.08	919	0.04	2.7e-05	5.5	3.87e-08	0.47	FALSE
Liver	Stard3	alternative TSS	NM_001014229.1	0.02	872	0.02	1.8e-03	5.45	4.97e-08	0.49	FALSE
Liver	Rpl19	gene expression	Rpl19	0.15	1	0.13	2.1e-14	5.26	1.46e-07	0.69	FALSE
Liver	Grb7	isoform ratio	XM_006247433.4	0.02	919	0.02	4.1e-03	-5.26	1.48e-07	0.44	FALSE
Liver	Smarce1	isoform ratio	NM_001399629.1	0.07	1	0.03	3.6e-04	-5.31	1.07e-07	0.11	TRUE
Liver	Med1	intron excision ratio	chr10_83174436_83175382	0.02	903	0.01	2.4e-02	-5.28	1.31e-07	0.4	FALSE
Liver	Zpbp2	intron excision ratio	chr10_83566539_83567063	0.03	1	0.03	7.2e-04	-5.22	1.75e-07	0.04	FALSE
Liver	Med1	mRNA stability	Med1	0.04	903	0.03	1.2e-04	-5.62	1.92e-08	0.52	FALSE
Liver	Ormdl3	mRNA stability	Ormdl3	0.04	1	0.04	2.8e-05	-5.31	1.07e-07	0.39	FALSE
NAcc	Arl5c	alternative polyA	XM_039086633.1	0.04	1	0.01	9.9e-03	-5.27	1.37e-07	0.11	FALSE
NAcc	Arl5c	alternative polyA	XM_039086634.1	0.06	1	0.02	1.8e-03	5.27	1.37e-07	0.32	FALSE
NAcc	Cacnb1	alternative polyA	NM_017346.2	0.19	1	0.07	4.4e-09	-5.19	2.10e-07	0.61	FALSE
NAcc	Cacnb1	alternative polyA	XM_006247411.4	0.21	1	0.08	4.0e-09	5.19	2.10e-07	0.61	FALSE
NAcc	Cisd3	gene expression	Cisd3	0.05	6	0.06	3.7e-07	-5.24	1.60e-07	0.5	TRUE
NAcc	Grb7	gene expression	Grb7	0.03	919	0.02	4.0e-03	-5.43	5.50e-08	0.5	FALSE
NAcc	Cacnb1	isoform ratio	XM_006247411.4	0.15	5	0.02	9.8e-04	5.31	1.12e-07	0.47	TRUE
NAcc	Zpbp2	intron excision ratio	chr10_83563545_83567063	0.02	1101	0.03	6.5e-04	-5.38	7.52e-08	0.47	FALSE
NAcc	Stac2	mRNA stability	Stac2	0.03	1	0.03	1.1e-04	5.3	1.16e-07	0.23	FALSE
OFC	Pcgf2	isoform ratio	NM_001105836.2	0.33	1	0.1	1.9e-03	-5.22	1.83e-07	0.06	FALSE
PL	Cwc25	alternative polyA	NM_001108295.2	0.09	15	0.11	3.1e-12	5.18	2.22e-07	0.56	FALSE
PL	Cwc25	alternative polyA	XM_039086393.1	0.09	1	0.11	2.0e-12	5.26	1.47e-07	0.71	FALSE
PL	Neurod2	alternative TSS	NM_019326.2	0.08	890	0.02	5.0e-03	5.67	1.39e-08	0.59	FALSE
PL	Neurod2	alternative TSS	XM_039086671.1	0.09	890	0.02	5.0e-03	-5.73	1.02e-08	0.58	TRUE
PL	Stac2	alternative TSS	XM_039086503.1	0.05	923	0.02	1.0e-03	5.22	1.76e-07	0.59	FALSE
PL	Stac2	alternative TSS	XM_039086504.1	0.05	923	0.02	1.0e-03	-5.21	1.88e-07	0.58	FALSE
PL	Stac2	alternative TSS	XM_039086503.1	0.04	923	0.02	2.0e-03	5.21	1.85e-07	0.58	FALSE
PL	Stac2	alternative TSS	XM_039086504.1	0.04	923	0.02	1.8e-03	-5.2	1.99e-07	0.58	FALSE
PL	Arl5c	gene expression	Arl5c	0.14	1	0.15	1.2e-16	5.24	1.57e-07	0.68	FALSE
PL	LOC108352129	gene expression	LOC108352129	0.06	4	0.06	8.2e-07	5.25	1.52e-07	0.42	FALSE
PL	Ormdl3	gene expression	Ormdl3	0.06	1095	0.08	8.5e-09	-5.42	5.80e-08	0.42	FALSE
PL	Rpl23	gene expression	Rpl23	0.03	1	0.02	2.1e-03	-5.26	1.44e-07	0.06	FALSE
PL	Mllt6	isoform ratio	XM_039087725.1	0.05	23	0.02	4.1e-03	5.23	1.71e-07	0.53	FALSE
PL	Rpl19	intron excision ratio	chr10_83018591_83023579	0.21	1	0.17	7.7e-18	-5.27	1.37e-07	0.7	FALSE
pVTA	Cacnb1	gene expression	Cacnb1	0.14	958	0.07	6.5e-04	5.19	2.08e-07	0.53	FALSE
pVTA	Ppp1r1b	gene expression	Ppp1r1b	0.07	25	0.02	4.1e-02	-5.18	2.21e-07	0.42	FALSE