Best TWAS P=2.7768e-07 · Best GWAS P=2.181712e-06 conditioned to 0.01739486
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NAcc | Med20 | mRNA stability | ENSRNOG00000013852 | 0.28 | 0.07 | enet | 45 | 0.14 | 0.00042 | -3.4 | 5.1 | 2.8e-07 | -0.53 | 0.32 | 0.31 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.