Hub : Traits : Body weight : ← : →

chr3:124,971,696-129,080,200

Trait: Body weight

Best TWAS P = 1.08e-08 · Best GWAS P= 1.60e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ehd4	gene expression	Ehd4	0.07	1486	0.04	3.7e-05	-5.52	3.41e-08	0.58	FALSE
Adipose	Gchfr	gene expression	Gchfr	0.17	10	0.07	1.5e-08	5.28	1.30e-07	0.83	FALSE
BLA	Ehd4	gene expression	Ehd4	0.35	11	0.28	6.0e-15	5.52	3.36e-08	0.81	FALSE
BLA	Mapkbp1	gene expression	Mapkbp1	0.19	34	0.13	2.9e-07	5.62	1.89e-08	0.69	FALSE
BLA	Sptbn5	gene expression	Sptbn5	0.26	90	0.19	1.7e-10	5.25	1.56e-07	0.5	FALSE
BLA	Zfyve19	isoform ratio	XM_039105683.2	0.17	1	0.04	4.1e-03	5.32	1.03e-07	0.12	FALSE
BLA	Bahd1	mRNA stability	Bahd1	0.12	1	0.05	1.0e-03	5.51	3.60e-08	0.12	FALSE
BLA	Ehd4	mRNA stability	Ehd4	0.09	1	0.05	1.2e-03	5.31	1.10e-07	0.06	FALSE
Brain	Ndufaf1	alternative TSS	XM_006234737.4	0.16	1599	0.22	1.0e-20	-5.46	4.80e-08	0.51	FALSE
Brain	Ndufaf1	alternative TSS	XM_006234740.5	0.11	1599	0.14	2.6e-13	5.47	4.41e-08	0.58	FALSE
Brain	Ndufaf1	alternative TSS	XM_006234737.4	0.18	1599	0.24	1.1e-22	-5.4	6.67e-08	0.48	FALSE
Brain	Ndufaf1	alternative TSS	XM_006234738.5	0.18	1599	0.24	1.5e-22	5.4	6.58e-08	0.48	FALSE
Brain	Pla2g4b	alternative TSS	XM_039104945.1	0.02	1	0.02	5.7e-03	5.23	1.65e-07	0.04	FALSE
Brain	Capn3	gene expression	Capn3	0.04	1580	0.05	1.4e-05	5.5	3.82e-08	0.53	FALSE
Brain	Ehd4	gene expression	Ehd4	0.29	1	0.26	1.2e-24	5.33	1.00e-07	0.67	FALSE
Brain	Fsip1	gene expression	Fsip1	0.12	117	0.12	1.7e-11	5.32	1.05e-07	0.68	FALSE
Brain	Jmjd7	gene expression	Jmjd7	0.08	1503	0.1	1.3e-09	5.47	4.43e-08	0.5	FALSE
Brain	LOC134486141	gene expression	LOC134486141	0.04	1	0.01	1.6e-02	-5.39	7.00e-08	0.12	FALSE
Brain	Pla2g4b	gene expression	Pla2g4b	0.15	1	0.21	4.8e-19	5.33	9.92e-08	0.65	FALSE
Brain	Rmdn3	gene expression	Rmdn3	0.08	1649	0.05	2.5e-05	-5.35	8.71e-08	0.76	FALSE
Brain	Sptbn5	gene expression	Sptbn5	0.25	14	0.25	1.9e-23	5.32	1.07e-07	0.72	FALSE
Brain	Cdan1	isoform ratio	XM_008762204.4	0.08	1	0.06	3.2e-06	-5.25	1.52e-07	0.86	FALSE
Brain	Cdan1	isoform ratio	XM_039106816.2	0.06	1	0.04	5.7e-05	5.25	1.52e-07	0.83	FALSE
Brain	Itpka	isoform ratio	NM_031045.2	0.04	1601	0.02	2.7e-03	5.4	6.70e-08	0.58	FALSE
Brain	Ndufaf1	isoform ratio	XM_006234737.4	0.05	1599	0.05	1.7e-05	-5.29	1.22e-07	0.47	FALSE
Brain	Pla2g4b	isoform ratio	XM_006234775.4	0.08	4	0.09	1.1e-08	5.28	1.32e-07	0.5	FALSE
Brain	Cdan1	intron excision ratio	chr3_128142492_128142686	0.07	1	0.05	8.3e-06	-5.25	1.52e-07	0.84	FALSE
Brain	Cdan1	intron excision ratio	chr3_128142495_128142686	0.07	1	0.05	1.2e-05	5.25	1.52e-07	0.83	FALSE
Brain	Sptbn5	intron excision ratio	chr3_127470788_127470871	0.04	1	0.03	1.2e-03	5.26	1.42e-07	0.04	FALSE
Brain	Ehd4	mRNA stability	Ehd4	0.11	27	0.11	4.9e-10	5.6	2.12e-08	0.78	FALSE
Brain	Mapkbp1	mRNA stability	Mapkbp1	0.09	1	0.09	1.8e-08	5.32	1.03e-07	0.64	FALSE
IC	Lrrc57	alternative TSS	XM_006234778.4	0.1	1764	0.04	6.5e-03	-5.46	4.63e-08	0.34	FALSE
IC	Lrrc57	alternative TSS	XM_006234778.4	0.08	6	0.04	9.7e-03	-5.31	1.10e-07	0.24	FALSE
IC	Ehd4	gene expression	Ehd4	0.39	1	0.23	6.5e-10	5.3	1.19e-07	0.63	FALSE
IC	Sptbn5	isoform ratio	XM_039106497.2	0.12	1	0.12	9.2e-06	5.32	1.05e-07	0.13	FALSE
IC	Sptbn5	isoform ratio	XM_039106500.2	0.11	1	0.08	2.4e-04	-5.26	1.42e-07	0.06	FALSE
IC	Cdan1	intron excision ratio	chr3_128142492_128142686	0.15	1	0.11	3.3e-05	-5.45	5.11e-08	0.81	FALSE
IC	Cdan1	intron excision ratio	chr3_128142495_128142686	0.15	1	0.13	5.4e-06	5.45	5.11e-08	0.81	FALSE
IC	Pla2g4b	intron excision ratio	chr3_127458196_127460407	0.08	1	0.05	4.5e-03	-5.58	2.40e-08	0.07	FALSE
IC	Sptbn5	intron excision ratio	chr3_127467945_127470706	0.12	9	0.09	1.9e-04	-5.49	4.13e-08	0.6	FALSE
IC	Sptbn5	intron excision ratio	chr3_127471321_127471833	0.16	11	0.13	5.9e-06	5.49	4.04e-08	0.6	FALSE
IL	Ehd4	gene expression	Ehd4	0.46	15	0.14	2.7e-04	5.42	6.07e-08	0.58	FALSE
IL	Lrrc57	gene expression	Lrrc57	0.39	1	0.13	4.2e-04	5.27	1.40e-07	0.06	FALSE
IL	Sptbn5	gene expression	Sptbn5	0.47	1	0.19	3.3e-05	5.26	1.42e-07	0.1	FALSE
IL	Snap23	intron excision ratio	chr3_127982332_127989968	0.27	1	0.08	7.0e-03	-5.43	5.50e-08	0.06	FALSE
IL	Mapkbp1	mRNA stability	Mapkbp1	0.21	1	0.09	3.2e-03	5.53	3.21e-08	0.06	FALSE
IL	Pak6	mRNA stability	Pak6	0.18	1	0.07	9.7e-03	-5.28	1.33e-07	0.06	FALSE
Liver	Bmf	gene expression	Bmf	0.13	23	0.06	5.2e-07	5.33	1.00e-07	0.64	FALSE
Liver	Disp2	gene expression	Disp2	0.04	1	0.02	4.7e-03	5.31	1.12e-07	0.06	FALSE
Liver	Ehd4	gene expression	Ehd4	0.38	19	0.26	5.8e-29	-5.33	1.00e-07	0.81	FALSE
Liver	Mapkbp1	gene expression	Mapkbp1	0.04	1505	0.01	3.8e-02	-5.26	1.47e-07	0.41	FALSE
Liver	Tmem62	intron excision ratio	chr3_128399842_128402601	0.09	9	0.02	4.7e-03	5.62	1.93e-08	0.82	FALSE
NAcc	Mga	alternative TSS	XM_008762120.4	0.01	1	0	5.0e-02	-5.27	1.39e-07	0.03	FALSE
NAcc	Fsip1	gene expression	Fsip1	0.44	158	0.28	1.7e-42	5.31	1.08e-07	0.6	FALSE
NAcc	Mapkbp1	isoform ratio	NM_001108589.1	0.05	1505	0.06	3.8e-09	5.6	2.14e-08	0.74	FALSE
NAcc	Mapkbp1	isoform ratio	XM_006234781.5	0.05	1505	0.05	1.8e-08	-5.62	1.93e-08	0.73	FALSE
NAcc	Stard9	isoform ratio	NM_001427830.1	0.03	19	0.01	2.4e-03	-5.28	1.31e-07	0.65	FALSE
NAcc	Cdan1	intron excision ratio	chr3_128142492_128142686	0.02	1503	0.02	7.0e-04	-5.32	1.06e-07	0.55	FALSE
NAcc	Ganc	intron excision ratio	chr3_127807634_127809474	0.02	1611	0.01	2.2e-03	-5.32	1.03e-07	0.25	FALSE
NAcc	Sptbn5	intron excision ratio	chr3_127467945_127470706	0.02	4	0.02	7.4e-04	-5.41	6.20e-08	0.62	FALSE
NAcc	Sptbn5	intron excision ratio	chr3_127471321_127471833	0.07	1	0.07	1.7e-11	5.31	1.10e-07	0.64	FALSE
NAcc	Ehd4	mRNA stability	Ehd4	0.04	1	0.04	6.6e-07	5.48	4.33e-08	0.8	FALSE
NAcc	Eif2ak4	mRNA stability	Eif2ak4	0.06	48	0.07	1.8e-10	5.32	1.03e-07	0.66	FALSE
NAcc	Itpka	mRNA stability	Itpka	0.05	12	0.06	8.3e-09	-5.6	2.15e-08	0.59	FALSE
PL	Ehd4	gene expression	Ehd4	0.33	15	0.3	1.2e-33	5.32	1.03e-07	0.82	FALSE
PL	Mapkbp1	gene expression	Mapkbp1	0.09	46	0.11	2.4e-12	5.72	1.08e-08	0.61	TRUE
PL	Rmdn3	gene expression	Rmdn3	0.07	1	0.06	1.9e-07	-5.33	1.00e-07	0.84	FALSE
PL	Pla2g4b	isoform ratio	XM_006234775.4	0.05	1497	0.04	3.0e-05	5.65	1.60e-08	0.47	FALSE
PL	Stard9	isoform ratio	NM_001427830.1	0.22	5	0.19	1.5e-20	-5.38	7.57e-08	0.34	FALSE
PL	Pla2g4b	intron excision ratio	chr3_127458196_127460407	0.04	156	0.04	2.4e-05	-5.22	1.82e-07	0.73	FALSE
PL	Sptbn5	intron excision ratio	chr3_127471321_127471833	0.07	1	0.07	1.7e-08	5.53	3.21e-08	0.85	FALSE
PL	Ivd	mRNA stability	Ivd	0.03	1870	0.01	2.5e-02	-5.25	1.54e-07	0.52	FALSE
pVTA	Exd1	gene expression	Exd1	0.05	1	0.05	6.9e-05	5.32	1.05e-07	0.18	FALSE
pVTA	Mapkbp1	isoform ratio	XM_006234781.5	0.03	1	0.02	4.4e-03	-5.56	2.75e-08	0.07	FALSE
pVTA	Ndufaf1	isoform ratio	NM_001106500.1	0.04	1	0.05	3.4e-05	-5.47	4.51e-08	0.3	FALSE
pVTA	Lrrc57	intron excision ratio	chr3_128006521_128006771	0.08	1	0.04	5.6e-04	5.33	9.87e-08	0.17	FALSE
pVTA	Ganc	mRNA stability	Ganc	0.48	122	0.1	1.6e-08	5.38	7.66e-08	0.41	FALSE
pVTA	Zfyve19	mRNA stability	Zfyve19	0.07	1	0.07	1.8e-06	-5.21	1.92e-07	0.65	FALSE