Ccdc186

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_039101455.1 0.07 0.04 7.4e-08 0.08 0.08 0.07 0.08 9.5e-08 4.3e-08 4.1e-07 7.1e-08
2 LHb isoform ratio XM_039101449.1 0.24 0.16 2.6e-03 0.06 0.09 0.05 0.08 1.7e-02 4.8e-03 2.8e-02 6.1e-03
3 Brain isoform ratio XM_039101449.1 0.07 0.05 1.5e-05 0.06 0.05 0.05 0.05 3.7e-06 1.1e-05 3.9e-05 3.0e-05
4 PL alternative TSS XM_039101450.1 0.03 0.03 8.0e-03 0 0.01 0.01 0.01 2.2e-01 1.9e-02 1.7e-02 5.9e-02
5 pVTA mRNA stability Ccdc186 0.39 0.11 2.3e-15 0.32 0.33 0.34 0.34 2.3e-14 4.2e-15 1.1e-15 1.4e-15
6 LHb mRNA stability Ccdc186 0.39 0.18 1.1e-05 0.13 0.2 0.09 0.16 6.0e-04 2.0e-05 4.9e-03 1.0e-04
7 OFC mRNA stability Ccdc186 0.33 0.17 8.5e-05 0.16 0.13 0.16 0.02 1.3e-04 5.9e-04 1.2e-04 1.1e-01
8 IL mRNA stability Ccdc186 0.39 0.17 1.1e-05 0.25 0.22 0.17 0.25 1.2e-06 5.2e-06 6.0e-05 8.7e-07
9 PL isoform ratio XM_039101455.1 0.07 0.04 3.2e-08 0.06 0.06 0.06 0.06 1.5e-07 5.5e-07 7.4e-07 5.0e-07
10 BLA mRNA stability Ccdc186 0.35 0.13 7.6e-15 0.24 0.23 0.2 0.23 3.1e-13 9.4e-13 3.6e-11 9.8e-13
11 Brain gene expression Ccdc186 0.05 0.03 9.7e-04 0.01 0.01 0.01 0.01 4.7e-02 1.4e-02 5.8e-02 3.3e-02
12 PL gene expression Ccdc186 0.08 0.05 2.9e-06 0.06 0.06 0.06 0.05 5.9e-07 2.0e-07 2.9e-07 1.4e-06
13 Brain mRNA stability Ccdc186 0.52 0.14 0.0e+00 0.52 0.52 0.52 0.52 2.7e-55 1.5e-55 7.0e-56 2.9e-56
14 NAcc mRNA stability Ccdc186 0.3 0.08 0.0e+00 0.26 0.26 0.26 0.27 1.8e-29 1.3e-30 3.7e-30 1.1e-30
15 Liver gene expression Ccdc186 0.06 0.04 3.6e-04 0.03 0.03 0.03 0.03 1.1e-04 3.2e-04 4.4e-04 1.5e-04
16 IL gene expression Ccdc186 0.2 0.13 3.3e-03 0.14 0.11 0.06 0.13 2.7e-04 1.4e-03 1.8e-02 5.6e-04
17 PL mRNA stability Ccdc186 0.53 0.13 0.0e+00 0.28 0.28 0.27 0.27 4.3e-31 1.9e-31 3.3e-30 1.0e-29
18 Adipose mRNA stability Ccdc186 0.06 0.05 3.4e-04 0.01 0.03 0.03 0.01 2.2e-02 2.9e-04 5.8e-04 8.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.01.75.61.4-2.00.9-1.80.7-0.30.1-0.1-0.10.12.42.1-0.0-0.32.2-2.1-0.20.5
Area under the delay curve0.50.52.10.9-0.80.9-1.50.0-0.30.3-0.00.1-0.20.71.3-0.00.30.9-0.60.80.7
BMI with tail4.313.832.15.7-5.44.8-4.24.1-4.13.9-3.5-3.33.33.33.4-3.2-3.42.6-1.9-2.4-1.8
BMI without tail1.63.49.03.0-2.92.0-2.41.7-1.91.9-1.5-1.21.22.02.3-1.2-1.41.9-1.3-0.7-0.4
Body weight4.518.843.26.6-6.35.8-4.44.9-4.74.5-4.2-4.04.03.73.9-3.9-4.02.7-2.4-2.9-2.2
Weight adjusted by age5.25.911.43.4-3.02.9-2.82.9-2.92.7-2.7-2.72.71.21.2-2.6-2.20.5-0.4-2.0-1.8
Bone surface0.40.71.81.0-1.20.5-1.20.7-0.40.2-0.2-0.40.41.31.2-0.3-0.51.3-1.2-0.20.3
Bone volume1.22.15.42.1-2.31.4-1.91.3-1.00.8-0.8-0.80.82.22.0-0.7-0.91.9-1.8-0.6-0.0
Breakpoint value in progressive ratio session0.80.92.9-0.30.2-0.3-0.3-1.01.0-0.81.01.0-1.00.51.11.11.21.0-0.61.71.5
Number of licking bursts0.50.61.80.3-0.70.6-0.4-0.50.5-0.20.50.7-0.71.21.30.60.71.3-1.10.90.8
Context. condit. distance diff. score1.11.32.9-1.41.6-1.41.7-1.31.3-0.70.91.1-1.1-1.1-0.71.01.3-0.70.81.20.7
Locomotion velocity, session 10.10.10.4-0.30.3-0.4-0.20.1-0.2-0.3-0.0-0.20.2-0.3-0.6-0.2-0.4-0.50.3-0.7-0.3
Locomotion distance, session 11.11.42.90.4-0.10.10.50.9-1.21.3-1.4-1.11.1-1.0-1.3-1.2-1.3-1.31.7-1.4-1.7
Locomotion velocity, session 21.61.93.8-0.00.4-0.11.70.9-1.01.2-1.3-1.21.2-1.5-1.9-1.4-1.3-1.92.0-1.7-1.9
Locomotion distance, session 21.82.64.21.3-0.81.10.31.8-1.92.0-2.0-1.91.9-0.7-0.9-2.0-2.0-1.21.4-2.0-2.1
Locomotion velocity, session 30.91.12.30.20.10.31.30.8-0.81.3-1.2-1.01.0-1.0-1.2-1.1-0.9-1.11.4-1.1-1.5
Locomotion distance, session 31.21.43.30.10.40.11.70.6-0.81.4-1.2-0.90.9-1.4-1.5-1.0-0.7-1.51.8-1.0-1.6
Stereotopy head waving bouts, day 30.10.10.60.2-0.50.8-0.00.2-0.10.3-0.2-0.10.10.50.1-0.0-0.20.4-0.2-0.4-0.4
Stereotopy head waving duration, day 30.20.20.7-0.2-0.30.3-0.5-0.30.4-0.60.50.4-0.40.80.40.50.40.7-0.80.10.3
Locomotion velocity, session 70.10.20.60.5-0.40.1-0.70.6-0.40.0-0.3-0.50.50.20.4-0.4-0.20.2-0.4-0.10.2
Locomotion distance, session 70.10.10.4-0.20.5-0.60.2-0.00.0-0.20.1-0.10.1-0.5-0.2-0.10.1-0.30.50.10.2
Stereotopy head waving bouts, day 70.10.10.30.1-0.10.4-0.00.4-0.1-0.1-0.0-0.30.30.20.1-0.3-0.10.0-0.6-0.20.0
Stereotopy head waving duration, day 70.60.71.91.1-1.11.3-1.41.0-0.80.3-0.5-0.80.80.80.8-0.7-0.80.5-1.1-0.5-0.1
Locomotion velocity, session 81.62.03.9-2.02.0-2.01.6-1.71.5-1.31.41.4-1.4-1.2-1.11.31.1-0.80.81.10.8
Locomotion distance, session 80.91.35.6-1.31.6-1.22.4-0.60.50.10.10.3-0.3-1.7-1.70.10.4-1.61.80.0-0.5
Degree of sensitization distance2.22.25.0-0.90.7-1.1-0.8-1.51.5-2.01.91.7-1.70.61.21.61.61.2-1.21.82.2
Degree of sensitization stereotypy0.10.10.50.1-0.10.1-0.60.3-0.1-0.30.1-0.30.30.10.3-0.2-0.10.0-0.70.00.3
Conditioned locomotion0.10.10.4-0.30.4-0.20.30.0-0.00.0-0.0-0.10.1-0.6-0.6-0.2-0.0-0.60.3-0.2-0.2
Cocaine response after cond. corrected1.61.85.6-1.31.8-1.31.7-0.3-0.10.1-0.2-0.10.1-2.3-2.4-0.3-0.4-2.32.3-0.5-0.9
Cocaine response after cond. not corrected1.51.64.4-1.61.9-1.51.7-0.60.4-0.40.20.3-0.3-2.0-2.10.20.1-2.11.9-0.1-0.5
Cocaine response before conditioning1.01.22.2-0.60.1-0.2-0.2-0.91.3-1.31.21.1-1.11.11.11.31.41.2-1.51.21.4
Saline control response0.40.61.20.2-0.10.30.50.8-0.70.7-0.9-0.90.9-0.5-0.9-0.9-0.8-0.90.7-1.0-1.1
Bone: connectivity density0.30.51.3-0.1-0.3-0.4-0.8-0.30.5-0.80.70.6-0.61.00.90.60.41.1-1.00.40.8
Bone: cortical apparent density2.12.86.9-0.10.80.01.90.8-1.21.6-1.5-1.31.3-2.3-2.4-1.5-1.4-2.62.6-1.4-2.1
Bone: cortical area5.68.518.64.2-4.34.0-3.13.2-2.92.7-2.7-2.72.72.92.6-2.5-2.52.1-2.1-2.0-1.5
Bone: cortical porosity0.20.20.7-0.1-0.3-0.10.1-0.30.5-0.30.50.5-0.50.80.50.50.30.8-0.70.20.3
Bone: cortical porosity0.50.61.4-0.1-0.3-0.2-0.0-0.60.8-0.50.80.8-0.81.10.90.80.71.2-1.10.70.8
Bone: cortical thickness3.15.210.63.1-3.13.3-1.62.7-2.42.5-2.5-2.32.31.71.4-2.3-2.30.9-1.0-2.0-1.8
Bone: cortical thickness1.31.52.71.6-1.41.6-0.21.4-1.51.6-1.5-1.31.30.30.2-1.4-1.5-0.10.2-1.2-1.3
Bone: cortical tissue density2.02.77.2-0.31.0-0.22.10.6-1.01.5-1.3-1.11.1-2.4-2.5-1.3-1.3-2.72.6-1.3-2.0
Condit. Reinf. active minus inactive responses0.20.21.4-0.20.00.11.2-0.00.00.5-0.4-0.10.1-0.1-0.6-0.1-0.0-0.50.6-0.6-0.8
Condit. Reinf. active-inactive response ratio0.10.10.5-0.30.1-0.40.7-0.30.30.10.00.2-0.20.1-0.30.30.3-0.10.2-0.2-0.4
Condit. Reinf. active responses0.70.92.30.9-1.21.20.01.1-0.90.9-1.1-1.01.00.80.0-0.9-1.00.2-0.1-1.5-1.3
Condit. Reinf. inactive responses1.41.73.31.4-1.81.8-1.11.6-1.20.8-1.2-1.31.31.40.6-1.2-1.40.8-0.8-1.8-1.2
Incentive salience index mean0.40.51.4-0.30.2-0.21.20.3-0.20.5-0.6-0.40.4-0.5-1.1-0.5-0.4-0.91.0-1.1-1.2
Condit. Reinf. lever presses0.30.41.5-0.0-0.0-0.10.30.6-0.50.4-0.6-0.70.7-0.3-0.9-0.6-0.7-0.70.6-1.2-1.1
Condit. Reinf. active minus inactive responses1.82.37.71.5-2.31.5-2.50.9-0.40.1-0.4-0.40.42.82.2-0.10.12.5-2.2-0.20.3
Condit. Reinf. active-inactive response ratio0.80.83.40.6-1.10.2-1.80.5-0.0-0.40.0-0.20.21.61.20.00.31.6-1.40.10.5
Condit. Reinf. active responses2.83.810.72.3-3.02.5-3.11.2-0.80.5-0.7-0.60.63.32.8-0.2-0.32.8-2.9-0.30.2
Condit. Reinf. inactive responses1.21.44.41.5-1.92.1-1.50.5-0.50.6-0.5-0.20.21.81.8-0.0-0.31.4-1.8-0.10.0
Condit. Reinf. lever presses0.60.82.30.8-1.10.8-1.2-0.10.1-0.10.20.3-0.31.41.50.40.31.5-1.50.50.6
Condit. Reinf. lever reinforcers received1.92.78.01.9-2.62.1-2.61.0-0.60.4-0.6-0.60.62.82.4-0.2-0.22.4-2.5-0.30.1
Conditioned reinforcement - actives1.71.73.5-0.10.60.11.50.9-0.91.0-1.2-1.31.3-1.6-1.8-1.3-1.2-1.91.7-1.4-1.6
Conditioned reinforcement - inactives0.40.51.80.8-0.71.3-0.10.8-0.80.8-0.8-0.80.80.20.1-0.7-0.6-0.2-0.1-0.8-0.8
Conditioned locomotion1.11.43.3-0.30.7-0.41.40.8-0.70.9-1.0-1.11.1-1.5-1.8-1.1-0.8-1.51.8-1.2-1.4
Patch foraging indifference point 0 sec2.33.78.32.7-2.82.9-2.62.0-1.91.1-1.3-1.41.42.12.1-1.3-1.61.5-2.0-1.2-0.5
Patch foraging indifference point AUC0.50.63.10.7-0.90.6-1.80.5-0.4-0.20.0-0.20.21.11.0-0.1-0.41.1-1.2-0.20.4
Delay disc. indifference point, 0s delay0.20.21.50.7-0.41.2-0.30.3-0.40.6-0.4-0.40.4-0.10.4-0.5-0.1-0.10.20.20.0
Delay disc. indifference point, 16s delay0.60.61.50.1-0.1-0.2-1.0-0.60.4-0.40.60.8-1.00.51.00.70.80.9-0.51.21.1
Delay disc. indifference point, 2s delay0.20.20.9-0.30.7-0.30.1-0.60.4-0.20.40.3-0.4-0.60.10.20.6-0.30.31.00.7
Delay disc. indifference point, 24s delay1.21.23.20.5-0.70.3-1.4-0.40.5-0.60.70.9-1.01.51.81.00.91.6-1.61.11.3
Delay disc. indifference point, 4s delay0.50.51.9-0.40.6-0.3-0.4-1.00.7-0.60.80.8-0.8-0.30.40.71.00.1-0.31.41.2
Delay disc. indifference point, 8s delay2.92.98.12.6-2.42.3-2.81.7-1.91.5-1.5-1.51.41.51.8-1.4-1.21.1-0.8-0.8-0.5
Indifference point function ln k0.10.20.5-0.10.0-0.20.70.2-0.10.3-0.3-0.40.4-0.3-0.6-0.4-0.3-0.60.3-0.7-0.7
Indifference point function log k0.10.20.5-0.10.0-0.20.70.2-0.10.3-0.3-0.40.4-0.3-0.6-0.4-0.3-0.60.3-0.7-0.7
Patch foraging total patch changes 0 sec2.23.68.02.7-2.82.8-2.81.8-1.71.0-1.2-1.31.32.22.2-1.1-1.51.7-2.2-1.1-0.3
Patch foraging total patch changes 12 sec1.01.34.61.2-1.31.2-2.10.4-0.4-0.30.10.00.01.61.90.1-0.11.7-2.00.30.9
Patch foraging total patch changes 18 sec2.33.09.92.1-2.52.3-3.11.2-1.10.4-0.5-0.50.52.52.4-0.4-0.82.4-2.3-0.40.4
Patch foraging total patch changes 24 sec1.92.38.91.7-1.91.6-3.00.7-0.7-0.0-0.0-0.30.32.22.4-0.1-0.42.2-2.20.31.0
Patch foraging total patch changes 6 sec3.04.510.33.0-3.23.2-3.12.0-1.81.3-1.4-1.21.22.62.6-1.1-1.42.2-2.2-1.0-0.3
Patch foraging time to switch 0 sec0.40.61.5-0.91.1-0.71.2-0.90.7-0.30.50.7-0.7-1.0-0.60.50.8-0.50.90.90.5
Patch foraging water rate 0 sec0.50.81.71.2-1.31.0-1.31.0-0.90.6-0.7-0.80.81.00.7-0.6-0.90.6-0.8-0.9-0.5
Patch foraging water rate 12 sec1.21.86.81.4-1.81.2-2.60.9-0.5-0.2-0.1-0.40.42.22.0-0.1-0.42.0-2.1-0.30.6
Patch foraging water rate 18 sec0.71.01.71.1-0.90.7-0.31.2-1.21.1-1.2-1.31.30.1-0.1-1.2-1.2-0.40.1-1.3-1.1
Patch foraging water rate 24 sec0.71.01.81.3-1.01.1-0.41.3-1.31.3-1.3-1.21.20.10.1-1.2-1.2-0.00.2-1.0-1.0
Patch foraging water rate 6 sec0.40.61.10.9-0.60.8-0.50.8-1.00.9-0.9-0.90.9-0.1-0.1-0.9-1.0-0.20.6-0.8-0.8
Seeking ratio, delayed vs. immediate footshock0.40.52.5-0.81.0-0.71.6-0.10.3-0.10.0-0.10.1-1.0-1.1-0.10.1-1.00.7-0.3-0.3
Distance traveled before self-admin0.50.52.6-0.51.0-0.21.0-0.3-0.10.2-0.1-0.00.0-1.5-1.1-0.1-0.2-1.60.80.0-0.4
Distance traveled after self-admin1.21.43.8-0.00.7-0.01.90.4-0.71.3-0.9-0.80.8-1.7-1.6-1.0-0.9-1.91.7-0.8-1.4
Extensor digitorum longus weight0.31.13.51.2-1.40.8-1.70.3-0.2-0.00.0-0.00.01.71.90.00.01.8-1.70.40.8
Bone: elastic displacement0.30.30.8-0.40.3-0.20.0-0.80.7-0.50.70.8-0.80.10.30.80.80.2-0.40.90.7
Bone: elastic work0.91.12.31.1-0.81.00.21.2-1.21.5-1.3-1.21.2-0.2-0.3-1.3-1.3-0.60.5-1.0-1.2
Bone: endosteal estimation0.81.63.51.9-1.81.5-1.71.4-1.21.0-1.0-1.21.21.41.4-1.0-1.11.2-1.0-0.7-0.3
Bone: endosteal perimeter3.16.413.63.7-3.53.2-2.83.0-2.82.6-2.6-2.62.62.01.9-2.4-2.41.4-1.2-1.9-1.4
Epididymis fat weight6.515.134.35.9-5.85.7-3.84.2-3.93.8-3.6-3.23.33.83.9-3.2-3.32.8-2.7-2.5-1.8
Delta time in closed arm before/after self-admin0.40.42.5-0.40.50.11.6-0.20.10.4-0.20.0-0.0-0.8-0.9-0.0-0.1-0.80.8-0.3-0.6
Delta time in open arm before/after self-admin0.30.31.20.4-0.70.2-1.00.20.1-0.20.20.0-0.01.00.90.10.21.1-0.80.20.4
Diff in mean of infusions in LGA sessions3.74.17.4-2.11.8-2.20.3-2.42.5-2.52.42.3-2.3-0.00.52.22.51.0-0.52.72.7
Delay discount exponential model param0.50.52.1-1.00.8-0.81.5-0.00.3-0.30.0-0.00.2-0.8-1.30.0-0.3-0.90.7-0.8-0.7
Extinction: sum of active levers before priming1.41.43.2-0.90.8-0.90.5-1.61.4-1.01.31.6-1.60.10.51.51.60.7-0.11.81.4
Active lever presses in extinction session 60.40.41.40.1-0.20.30.8-0.90.50.50.21.0-1.00.20.50.60.70.4-0.01.20.3
Bone: final force2.54.07.02.6-2.51.9-1.62.6-2.42.2-2.2-2.32.31.10.8-2.3-2.40.6-0.4-2.0-1.6
Bone: final moment2.33.87.02.6-2.51.9-1.62.5-2.32.1-2.1-2.22.21.21.0-2.2-2.20.7-0.6-1.8-1.5
Food consumed during 24 hour testing period0.40.52.7-0.70.4-0.31.6-0.90.9-0.00.41.0-1.0-0.1-0.20.71.0-0.10.30.60.0
Glucose2.84.213.02.9-3.03.6-1.52.2-2.02.2-2.0-1.81.81.81.7-1.7-1.71.3-1.3-1.4-1.2
Heart weight1.92.75.42.3-2.12.2-1.52.0-1.91.8-1.8-1.71.70.90.9-1.7-1.60.3-0.6-1.4-1.3
Delay discount hyperbolic model param0.30.41.5-0.70.5-0.61.20.10.1-0.1-0.0-0.10.3-0.5-1.1-0.0-0.4-0.70.5-0.8-0.7
Intermittent access intake day 1-15 change1.41.45.41.8-1.72.3-1.31.0-1.21.2-1.0-0.80.91.01.2-0.9-0.70.5-0.8-0.4-0.5
Intermittent access intake escalation2.52.56.22.1-1.72.5-0.61.7-1.92.1-1.9-1.61.60.20.4-1.8-1.6-0.50.2-1.2-1.6
Intermittent access intake escalation 21.41.43.01.3-0.91.70.21.2-1.41.7-1.6-1.21.3-0.4-0.2-1.4-1.2-0.90.6-1.0-1.4
Intermitt. access day 1 inactive lever presses1.11.24.21.3-1.51.2-2.00.6-0.50.1-0.1-0.20.21.61.8-0.0-0.11.5-1.50.20.6
Intermitt. access day 15 inactive lever presses0.10.10.20.5-0.40.5-0.40.3-0.30.4-0.3-0.20.20.10.2-0.1-0.2-0.0-0.10.1-0.1
Intermitt. access escalation Index0.20.21.1-0.30.40.11.1-0.60.30.10.20.5-0.4-0.5-0.30.20.2-0.70.10.3-0.1
Intermittent access day 1 total infusions0.10.20.40.3-0.00.10.10.5-0.50.5-0.5-0.60.6-0.4-0.3-0.6-0.4-0.30.5-0.3-0.4
Intermittent access day 15 total infusions0.91.02.11.3-0.81.4-0.11.0-1.21.4-1.2-1.11.1-0.40.0-1.3-1.0-0.70.4-0.6-1.0
Intermittent access terminal intake (last 3 days)0.50.61.20.9-0.40.90.00.8-1.01.0-1.0-1.01.0-0.4-0.1-1.1-0.8-0.60.4-0.5-0.7
Intermittent access total infusions1.31.42.61.2-0.81.2-0.41.5-1.51.3-1.5-1.61.6-0.4-0.3-1.6-1.4-0.90.5-1.2-1.3
Intermittent access day 1 locomotion0.70.71.90.00.6-0.40.40.6-0.70.7-0.8-0.90.8-1.4-1.1-0.9-0.7-1.21.4-0.4-0.7
Intermittent access day 15 total locomotion1.92.04.42.1-1.92.0-1.91.6-1.61.4-1.5-1.51.51.01.1-1.5-1.10.6-0.6-0.8-0.8
Intermittent access total locomotion1.82.13.81.0-0.30.6-0.31.7-1.81.5-1.7-1.91.9-1.1-1.0-1.9-1.7-1.41.3-1.5-1.6
Intermittent access standard deviation0.40.51.50.8-0.91.2-1.10.2-0.2-0.0-0.0-0.00.10.91.20.10.10.7-1.10.30.4
Left kidney weight3.49.717.02.5-1.32.31.73.4-3.54.1-3.9-3.63.6-1.8-1.8-3.9-3.6-2.72.7-3.3-3.9
Right kidney weight5.214.724.04.1-3.03.5-0.64.7-4.84.7-4.7-4.74.7-0.5-0.7-4.8-4.9-2.01.6-4.5-4.3
Cocaine induced anxiety3.64.19.7-3.03.0-2.73.1-2.12.0-1.41.51.6-1.6-2.3-2.31.41.4-1.71.81.20.6
Post-drug Anxiety1.01.13.3-1.41.5-1.31.8-1.21.0-0.40.70.9-0.9-1.3-1.20.70.6-0.91.30.70.2
Baseline Anxiety3.53.79.22.9-3.02.7-2.71.7-1.71.6-1.4-1.21.22.42.4-1.1-1.21.9-1.7-0.7-0.4
Tail length0.10.30.80.5-0.70.9-0.20.00.10.20.00.2-0.20.80.90.20.20.9-0.80.30.3
Length with tail1.14.08.52.9-2.72.9-1.12.4-2.12.2-2.2-2.12.11.41.3-2.1-1.90.8-0.9-1.6-1.4
Length without tail3.27.114.13.5-3.43.8-1.53.3-2.92.8-3.0-2.92.91.61.3-2.9-2.80.6-0.8-2.6-2.3
Times rat made contact with spout0.30.41.00.5-0.30.60.70.5-0.61.0-0.8-0.50.5-0.4-0.3-0.7-0.6-0.60.7-0.5-0.8
Lifetime Intake1.51.73.01.3-0.81.3-0.31.6-1.61.5-1.6-1.71.7-0.5-0.4-1.7-1.5-1.00.7-1.4-1.5
Liver weight, left1.72.86.82.6-2.62.4-1.91.7-1.51.5-1.3-1.11.21.92.1-1.1-1.01.4-1.7-0.7-0.4
Liver weight, right3.45.713.33.6-3.43.5-2.22.8-2.62.6-2.4-2.22.21.92.1-2.2-2.11.3-1.3-1.5-1.2
Locomotor activity1.11.72.81.7-1.51.6-0.01.5-1.51.6-1.6-1.51.50.30.3-1.5-1.5-0.3-0.1-1.4-1.4
Locomotor testing distance2.13.45.51.9-1.52.20.22.1-2.22.3-2.3-2.22.2-0.3-0.4-2.2-2.2-1.10.7-2.1-2.3
Locomotor testing rearing0.71.12.41.2-0.91.50.31.2-1.21.4-1.4-1.21.2-0.2-0.0-1.2-1.0-0.70.2-0.8-1.2
Locomotion in novel chamber0.81.03.0-0.20.7-0.41.50.3-0.50.9-0.7-0.30.3-1.5-1.5-0.6-0.7-1.71.6-0.6-1.1
Locomotion in novel chamber post-restriction1.51.95.3-0.81.0-1.21.80.6-0.50.5-0.8-0.90.9-1.7-2.3-1.0-1.0-2.12.0-1.6-1.6
Fecal boli incidents, locomotor time 11.41.54.41.3-1.71.7-2.11.4-1.10.3-0.8-1.11.11.50.9-0.7-0.90.7-1.3-1.5-0.6
Change in fecal boli incidents, locomotor task2.82.64.5-1.91.7-2.12.1-2.01.9-1.11.52.0-2.0-0.8-0.61.71.7-0.20.61.81.2
Time >=10cm from walls, locomotor time 11.51.53.7-1.81.5-1.91.5-1.51.5-1.21.31.3-1.3-0.5-0.71.21.2-0.10.10.90.8
Bouts of movement, locomotor time 10.70.74.00.9-1.00.8-2.00.4-0.4-0.2-0.1-0.20.31.11.3-0.1-0.21.1-1.40.20.6
Total resting periods, locomotor time 10.40.52.70.9-0.80.6-1.60.5-0.50.0-0.2-0.40.40.70.9-0.3-0.40.7-1.0-0.10.4
Rest time, locomotor task time 11.11.22.20.7-0.30.3-0.41.3-1.31.0-1.3-1.41.3-0.7-0.8-1.3-1.5-0.91.0-1.4-1.2
Distance moved, locomotor task time 10.70.82.3-0.30.0-0.40.4-1.11.0-0.40.91.2-1.20.50.91.01.20.8-0.71.51.0
Vertical activity count, locomotor time 11.01.12.1-1.11.0-0.91.5-1.51.3-0.51.01.4-1.4-0.4-0.21.11.2-0.10.21.40.7
Time >=10cm from walls, locomotor time 20.50.60.9-0.3-0.1-0.20.4-0.70.9-0.70.80.8-0.80.80.80.80.81.0-1.00.80.8
Bouts of movement, locomotor time 21.71.84.5-1.72.0-2.11.0-1.51.4-1.41.41.1-1.1-1.2-0.61.11.2-0.30.71.51.4
Total resting periods, locomotor time 21.11.22.9-1.31.6-1.70.6-1.21.0-1.01.10.9-0.9-1.1-0.40.81.0-0.20.71.51.3
Rest time, locomotor task time 20.20.20.50.5-0.20.3-0.30.3-0.70.7-0.7-0.50.5-0.3-0.1-0.5-0.5-0.50.4-0.3-0.5
Distance moved, locomotor task time 20.20.30.80.4-0.60.2-0.70.00.1-0.10.20.2-0.20.90.90.20.20.9-0.80.20.4
Vertical activity count, locomotor time 20.20.20.60.3-0.60.8-0.40.3-0.0-0.10.00.1-0.00.80.50.1-0.20.6-0.7-0.2-0.0
Light reinforcement 11.12.04.0-2.01.9-2.01.5-1.71.6-1.31.41.4-1.4-1.2-1.01.31.4-0.50.81.30.9
Light reinforcement 21.52.05.0-2.12.2-2.02.0-1.31.3-1.11.20.8-0.8-1.7-1.60.81.0-1.21.40.70.5
Bone: marrow area0.81.73.61.9-1.91.5-1.71.4-1.21.0-1.0-1.21.21.41.4-1.1-1.11.3-1.0-0.7-0.3
Bone: maximum diameter4.48.119.24.1-4.44.1-3.42.9-2.52.3-2.2-2.22.23.43.2-2.0-2.12.7-2.7-1.5-0.9
Bone: maximum force2.23.76.32.5-2.42.0-1.22.4-2.22.2-2.2-2.22.21.20.8-2.1-2.20.6-0.5-2.0-1.7
Bone: maximum moment2.03.46.12.5-2.42.0-1.22.3-2.12.1-2.1-2.12.11.30.9-2.0-2.10.7-0.6-1.9-1.6
Mean time between licks in bursts0.30.40.6-0.3-0.1-0.10.3-0.60.8-0.50.60.7-0.70.80.60.80.80.8-0.70.50.6
Mean num. licks in bursts1.51.83.40.40.10.20.91.2-1.31.3-1.4-1.41.4-1.4-1.6-1.4-1.5-1.81.6-1.7-1.8
Cd content in liver1.61.84.4-2.01.7-2.10.9-1.51.6-1.71.51.3-1.3-0.5-0.81.31.4-0.30.20.91.0
Co content in liver0.30.41.0-0.20.3-0.50.00.7-0.50.0-0.4-0.70.7-0.6-0.9-0.7-0.8-0.80.7-1.0-0.7
Cu content in liver0.30.40.70.5-0.3-0.1-0.20.7-0.80.6-0.7-0.70.7-0.3-0.4-0.7-0.9-0.50.4-0.8-0.7
Fe content in liver0.00.00.2-0.0-0.30.20.10.20.1-0.2-0.1-0.10.10.50.1-0.0-0.00.4-0.2-0.2-0.1
K content in liver0.30.31.2-0.70.8-1.1-0.1-0.50.5-0.90.80.5-0.5-0.3-0.10.50.4-0.1-0.10.50.7
Mg content in liver0.50.51.1-0.30.3-0.9-0.6-0.60.6-0.90.80.7-0.70.30.60.70.60.6-0.70.91.1
Mn content in liver0.91.02.0-1.21.4-1.31.1-1.21.0-0.91.01.1-1.1-1.0-0.50.90.9-0.60.51.10.8
Na content in liver0.80.82.0-0.60.5-0.5-0.7-0.90.9-1.31.10.9-0.90.30.60.90.90.6-0.91.31.4
Rb content in liver1.72.13.6-1.61.4-1.20.4-1.81.7-1.91.91.8-1.8-0.20.11.81.70.3-0.41.71.7
Se content in liver0.10.20.3-0.20.1-0.4-0.4-0.30.4-0.60.50.3-0.30.40.30.40.30.5-0.50.40.6
Sr content in liver1.81.64.0-1.62.0-1.91.5-0.90.7-0.80.80.7-0.7-2.0-1.70.50.6-1.81.80.40.1
Zn content in liver1.41.56.0-1.51.9-2.41.4-1.10.8-0.70.80.8-0.8-1.6-1.40.70.6-1.31.40.50.3
Bone: minimum diameter1.83.37.72.6-2.82.5-2.31.8-1.51.4-1.3-1.41.42.22.2-1.2-1.32.0-1.8-0.8-0.3
Time in familiar zone, hab. session 10.20.20.40.1-0.1-0.2-0.10.6-0.40.3-0.5-0.60.6-0.2-0.5-0.5-0.5-0.50.4-0.7-0.6
Time in novel zone, hab. session 10.50.51.50.5-0.60.8-0.7-0.30.2-0.20.40.5-0.51.01.20.40.41.2-1.00.70.8
Total zone transitions, hab. session 11.31.83.21.6-1.01.4-0.31.6-1.81.7-1.8-1.61.6-0.4-0.2-1.7-1.7-0.70.7-1.2-1.4
Total locomotion distance, hab. session 10.20.21.5-0.40.40.31.2-0.60.50.00.20.5-0.5-0.3-0.20.40.6-0.20.40.50.0
Locomotion velocity, hab. session 10.20.32.0-0.60.60.11.4-0.70.6-0.00.20.5-0.5-0.6-0.50.40.6-0.40.60.5-0.0
Time in familiar zone, hab. session 21.31.44.11.0-1.40.8-1.9-0.10.2-0.20.30.5-0.52.02.00.50.72.0-1.70.70.9
Time in novel zone, hab. session 21.41.43.1-0.20.6-0.11.40.9-0.80.8-1.0-1.21.2-1.5-1.7-1.1-1.2-1.81.4-1.4-1.4
Total zone transitions, hab. session 21.41.83.21.7-1.21.5-0.61.6-1.71.8-1.8-1.51.5-0.10.1-1.7-1.5-0.40.7-1.1-1.3
Total locomotion distance, hab. session 20.20.31.20.5-0.30.80.80.3-0.41.1-0.8-0.30.3-0.2-0.2-0.4-0.1-0.20.8-0.2-0.7
Locomotion velocity, hab. session 20.20.20.90.3-0.10.60.90.1-0.30.9-0.6-0.20.2-0.4-0.3-0.3-0.1-0.30.8-0.1-0.6
Novel to familiar place preference ratio0.30.30.8-0.2-0.30.20.1-0.30.6-0.60.60.4-0.40.90.60.60.50.8-0.90.10.4
Novelty place preference0.20.20.9-0.0-0.40.30.1-0.10.4-0.40.40.2-0.20.90.60.40.30.7-0.9-0.10.3
Time in novel zone, NPP test0.50.52.00.3-0.80.6-0.4-0.00.4-0.40.40.2-0.21.31.10.40.41.1-1.40.10.5
Total zone transitions, NPP test0.30.51.30.9-0.40.50.00.6-0.91.2-1.0-0.60.6-0.4-0.0-0.8-0.8-0.50.7-0.4-0.6
Total locomotion distance, NPP test0.10.21.4-0.00.10.31.2-0.40.20.6-0.20.4-0.4-0.3-0.10.10.3-0.20.60.3-0.2
Locomotion velocity, NPP test0.30.53.1-0.40.6-0.21.8-0.60.30.6-0.10.4-0.4-0.9-0.70.20.3-0.71.20.3-0.4
Intraocular pressure2.83.99.32.7-3.12.9-2.82.0-1.71.4-1.5-1.41.42.52.1-1.2-1.21.9-1.8-1.1-0.7
Delta distance traveled before/after self-admin0.50.51.60.6-0.30.20.90.6-0.71.3-0.9-0.70.7-0.5-0.3-0.8-0.6-0.41.0-0.5-0.8
Delta ambulatory time before/after self-admin0.10.10.50.5-0.40.20.40.4-0.30.7-0.5-0.40.40.10.2-0.4-0.20.10.2-0.2-0.3
Parametrial fat weight4.58.820.74.2-4.63.9-4.42.7-2.21.7-1.7-1.81.74.04.0-1.5-1.43.6-3.4-0.9-0.0
Pavlov. Cond. lever latency0.40.51.20.1-0.40.2-0.6-0.50.4-0.40.50.6-0.60.81.00.70.70.9-1.10.90.8
Pavlov. Cond. magazine entry latency0.10.10.60.2-0.10.50.80.1-0.10.6-0.4-0.10.1-0.3-0.2-0.2-0.0-0.40.5-0.1-0.4
Pavlov. Cond. change in total contacts0.10.10.20.10.1-0.00.30.2-0.20.3-0.2-0.20.2-0.3-0.3-0.3-0.3-0.40.5-0.2-0.3
Pavlov. Cond. index score0.10.20.50.4-0.20.40.40.4-0.40.7-0.6-0.40.4-0.2-0.2-0.5-0.4-0.40.4-0.4-0.6
Pavlov. Cond. latency score0.20.20.40.3-0.20.30.30.5-0.50.7-0.6-0.50.5-0.3-0.3-0.5-0.5-0.40.5-0.6-0.6
Pavlov. Cond. lever contacts0.10.10.30.1-0.0-0.0-0.10.4-0.40.3-0.4-0.50.5-0.2-0.4-0.4-0.4-0.30.4-0.6-0.4
Pavlov. Cond. magazine entry number0.50.71.7-1.00.9-1.3-0.3-0.80.8-1.31.10.8-0.8-0.2-0.10.80.60.2-0.30.81.0
Pavlov. Cond. intertrial magazine entries0.40.41.50.4-0.50.50.30.8-0.60.5-0.7-0.80.80.3-0.4-0.7-0.8-0.1-0.1-1.2-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.3-0.30.40.30.3-0.20.6-0.4-0.30.3-0.0-0.0-0.3-0.2-0.20.3-0.3-0.4
Pavlov. Cond. response bias0.30.40.90.4-0.30.70.70.5-0.51.0-0.8-0.60.6-0.3-0.4-0.7-0.5-0.60.7-0.7-0.9
Pavlov. Cond. lever latency0.50.61.8-0.50.8-0.61.20.1-0.20.4-0.4-0.40.4-1.3-1.3-0.4-0.2-1.31.4-0.3-0.7
Pavlov. Cond. magazine entry latency0.30.41.50.8-0.81.0-0.40.0-0.00.3-0.10.1-0.10.81.20.00.30.9-0.90.60.5
Pavlov. Cond. change in total contacts0.60.92.71.1-1.51.2-1.30.4-0.30.2-0.2-0.10.11.61.50.0-0.11.4-1.5-0.00.2
Pavlov. Cond. index score0.60.81.91.2-1.41.4-1.00.5-0.40.5-0.4-0.20.21.31.4-0.2-0.21.2-1.2-0.00.1
Pavlov. Cond. latency score0.50.71.91.1-1.31.2-0.90.3-0.30.4-0.2-0.10.11.31.4-0.1-0.11.2-1.20.10.2
Pavlov. Cond. lever contacts0.20.30.90.7-0.80.9-0.70.1-0.20.2-0.00.0-0.00.90.90.0-0.10.9-0.80.10.2
Pavlov. Cond. magazine entry number0.30.41.3-0.80.8-0.90.30.00.1-0.40.1-0.10.1-0.8-1.1-0.0-0.2-0.80.8-0.5-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.40.2-0.20.2-0.5-0.10.1-0.10.10.2-0.20.40.60.30.40.5-0.50.50.4
Pavlov. Cond. lever-magazine prob. diff.0.50.72.01.2-1.41.4-0.90.6-0.60.7-0.5-0.40.41.21.2-0.4-0.40.9-1.0-0.2-0.1
Pavlov. Cond. response bias0.40.61.71.0-1.11.3-0.80.2-0.20.3-0.10.0-0.01.21.3-0.0-0.01.1-1.10.20.3
Time in closed arm before self-admin0.00.10.30.10.2-0.5-0.3-0.0-0.10.00.0-0.00.0-0.4-0.0-0.0-0.0-0.4-0.10.30.2
Time in closed arm after self-admin0.50.51.7-0.81.1-1.01.3-0.50.3-0.10.30.3-0.3-1.3-0.90.20.1-1.20.70.30.0
Time in open arm before self-admin1.51.73.1-1.71.3-0.91.7-1.71.8-1.21.41.6-1.6-0.2-0.41.61.50.30.31.30.9
Time in open arm after self-admin0.40.40.9-0.60.1-0.1-0.2-0.60.8-1.00.80.7-0.70.70.40.70.70.9-0.60.50.7
Bone: periosteal estimation3.16.513.63.7-3.73.3-2.72.9-2.62.4-2.4-2.42.42.52.3-2.3-2.31.9-1.8-1.7-1.2
Bone: periosteal perimeter6.911.423.84.9-4.74.3-3.93.9-3.73.3-3.3-3.33.32.82.7-3.1-3.22.0-1.9-2.4-1.8
Bone: post-yield work0.20.20.5-0.40.1-0.3-0.0-0.40.7-0.60.60.5-0.50.50.40.50.60.6-0.60.50.6
Progressive ratio test 1 active lever presses1.51.63.41.1-0.61.20.51.3-1.41.8-1.7-1.51.4-0.7-0.7-1.5-1.2-1.01.2-1.0-1.6
Progressive ratio test 1 breakpoint0.80.81.50.7-0.40.80.41.0-1.01.2-1.2-1.21.1-0.5-0.5-1.1-0.8-0.60.9-0.7-1.1
Progressive ratio test 1 inactive lever presses0.10.10.80.1-0.00.70.9-0.1-0.00.6-0.3-0.00.0-0.3-0.2-0.10.1-0.60.30.1-0.4
Progressive ratio test 2 active lever presses2.52.74.72.0-1.41.9-0.82.0-2.22.1-2.1-2.02.0-0.30.0-2.1-1.8-0.70.8-1.3-1.6
Progressive ratio test 2 breakpoint2.12.44.22.0-1.41.8-1.01.9-2.12.0-1.9-1.91.8-0.20.1-1.9-1.7-0.60.6-1.1-1.4
Progressive ratio test 2 inactive lever presses0.60.71.91.2-1.11.4-0.90.9-0.80.6-0.7-0.80.80.60.7-0.8-0.60.3-0.7-0.5-0.3
Incentive Sensitization - Responses1.31.33.01.7-1.31.6-1.51.4-1.51.1-1.2-1.31.30.40.7-1.2-1.20.1-0.2-0.7-0.6
Incentive Sensitization - Breakpoint1.41.43.21.8-1.51.7-1.71.4-1.51.1-1.2-1.21.20.60.9-1.2-1.20.2-0.3-0.6-0.6
Sum of active levers in priming session hrs 5-61.71.63.3-1.61.4-1.80.8-1.61.6-1.41.41.4-1.4-0.3-0.21.41.50.3-0.01.51.3
Progressive ratio0.50.61.1-1.00.7-0.51.0-1.01.0-0.50.71.0-1.0-0.2-0.30.90.9-0.00.20.80.4
Food seeking constrained by brief footshock1.72.14.1-1.00.8-1.00.2-2.01.7-1.21.71.9-1.90.40.81.91.80.9-0.92.01.7
Seeking ratio, punishment vs. effort0.00.00.20.10.1-0.3-0.4-0.1-0.0-0.20.20.0-0.0-0.00.30.00.1-0.0-0.40.20.4
Retroperitoneal fat weight6.220.346.76.8-6.66.3-5.05.1-4.84.3-4.2-4.04.04.14.4-3.8-3.83.1-2.9-2.8-2.0
Reaction time number correct0.50.72.11.1-1.11.2-1.50.6-0.60.2-0.3-0.50.51.01.2-0.2-0.40.8-1.0-0.00.3
Reaction time mean minus median0.60.82.21.2-1.00.7-0.40.9-1.21.5-1.2-0.90.90.10.1-1.0-0.9-0.10.3-0.7-1.1
Reaction time mean minus median AUC0.91.23.01.2-0.60.70.11.1-1.41.7-1.4-1.21.2-0.7-0.5-1.4-1.2-0.91.0-0.9-1.3
Reaction time num false alarms0.00.10.4-0.10.2-0.60.10.1-0.1-0.20.0-0.00.0-0.2-0.2-0.1-0.3-0.20.2-0.3-0.0
Reaction time num false alarms AUC0.10.20.40.10.1-0.30.20.3-0.40.2-0.3-0.30.3-0.5-0.5-0.4-0.6-0.50.6-0.5-0.4
Reaction time trials correct on left0.50.72.11.1-1.11.2-1.50.6-0.60.2-0.3-0.50.51.01.2-0.2-0.40.8-1.0-0.00.3
Reaction time trials on left0.50.72.31.2-1.21.2-1.50.7-0.60.2-0.4-0.60.51.01.2-0.3-0.40.8-1.0-0.00.3
Reaction time mean0.50.71.61.1-0.81.0-0.41.0-1.21.3-1.0-0.80.9-0.0-0.0-1.0-1.0-0.30.3-0.8-1.0
Reaction time mean AUC0.20.30.70.6-0.40.6-0.20.6-0.80.8-0.6-0.50.5-0.2-0.1-0.7-0.7-0.40.3-0.5-0.7
Median of all reaction times0.50.71.30.9-0.61.0-0.31.0-1.11.1-1.0-0.90.9-0.3-0.2-1.0-1.1-0.50.4-0.9-1.0
Reaction time omissions0.20.30.80.8-0.70.2-0.90.7-0.60.3-0.4-0.50.50.40.5-0.5-0.50.5-0.2-0.2-0.0
Reaction time false alarm rate0.20.20.9-0.60.7-0.90.7-0.20.1-0.20.10.2-0.2-0.7-0.8-0.0-0.1-0.60.7-0.2-0.2
Reaction time premature initiation rate1.41.93.10.8-0.31.20.61.5-1.51.6-1.6-1.71.7-1.0-1.1-1.8-1.4-1.41.3-1.6-1.7
Reaction time premature initiations1.82.54.41.5-1.01.9-0.21.9-1.91.9-2.0-2.12.1-0.5-0.5-2.0-1.8-1.00.8-1.7-1.7
Std. dev. reaction times1.62.24.32.1-1.81.8-1.01.7-1.92.0-1.8-1.51.50.50.5-1.6-1.60.10.1-1.3-1.5
Reaction time trials completed0.50.72.31.2-1.21.2-1.50.7-0.60.2-0.4-0.60.51.01.2-0.3-0.40.8-1.0-0.00.3
Reaction time trials AUC0.50.82.41.2-1.21.3-1.60.8-0.70.3-0.4-0.60.61.01.2-0.4-0.50.8-1.1-0.20.2
Run reversals in cocaine runway, females1.21.22.31.1-0.90.7-0.31.5-1.31.2-1.3-1.41.40.0-0.3-1.3-1.3-0.40.3-1.5-1.3
Run reversals in cocaine runway, males2.32.33.6-1.81.7-1.50.9-1.91.8-1.71.81.8-1.8-0.7-0.21.71.7-0.1-0.11.81.6
Latency to leave start box in cocaine runway0.91.02.4-0.80.9-1.10.5-1.41.1-0.51.01.3-1.3-0.30.11.21.30.50.61.51.0
Latency to leave start box in cocaine runway, F1.01.12.2-1.11.0-1.40.7-1.51.2-0.61.01.4-1.4-0.4-0.11.21.40.30.51.40.9
Latency to leave start box in cocaine runway, M0.10.10.30.6-0.20.4-0.40.3-0.50.4-0.4-0.30.3-0.20.2-0.3-0.3-0.10.30.1-0.0
Std. dev. time between licks in bursts0.20.20.7-0.70.5-0.80.3-0.40.7-0.80.60.4-0.40.1-0.00.50.50.3-0.00.20.5
Total sessions with >9 infusions6.87.412.02.8-2.23.0-0.63.3-3.33.2-3.3-3.53.3-0.3-0.6-3.2-3.1-1.31.3-3.2-3.2
Short access day 1 total inactive lever presses0.10.21.30.1-0.10.71.2-0.30.20.6-0.20.2-0.2-0.10.00.20.3-0.30.10.3-0.3
Short access day 10 total inactive lever presses0.40.51.51.0-1.11.0-1.20.6-0.60.3-0.3-0.40.40.90.9-0.3-0.40.6-0.8-0.5-0.1
Short access day 1 total infusions1.31.32.30.7-0.20.90.91.1-1.21.4-1.4-1.31.3-1.0-0.9-1.3-1.2-1.41.2-1.2-1.5
Short access day 10 total infusions0.80.91.60.40.00.50.70.8-1.01.1-1.1-1.11.1-1.0-1.0-1.0-0.9-1.21.1-0.9-1.3
Short access total infusions1.41.62.60.8-0.30.90.51.3-1.41.5-1.5-1.61.5-0.9-0.9-1.6-1.4-1.31.2-1.3-1.6
Short access day 1 locomotion0.80.91.91.0-0.61.0-0.01.0-1.21.4-1.3-1.11.1-0.5-0.3-1.1-0.9-0.70.8-0.7-1.1
Short access day 10 total locomotion0.60.61.20.9-0.50.8-0.40.9-1.01.1-1.0-1.01.0-0.4-0.2-0.9-0.9-0.40.7-0.5-0.8
Short access total locomotion2.83.05.01.1-0.20.80.11.9-2.01.9-2.1-2.22.2-1.5-1.3-2.2-2.0-1.71.9-1.7-1.9
One hour access (0.3 mA shock)0.60.72.91.2-1.21.7-0.80.5-0.50.6-0.5-0.40.40.91.2-0.3-0.20.5-1.10.1-0.1
Compulsive drug intake0.80.81.6-0.70.3-0.50.0-1.11.1-0.91.11.2-1.20.50.51.31.10.7-0.70.90.9
One hour access (shock baseline)1.82.03.51.8-1.31.9-0.71.8-1.81.6-1.7-1.81.80.00.2-1.8-1.5-0.50.1-1.3-1.3
Social response proportion3.23.45.91.7-1.01.20.62.1-2.22.4-2.3-2.22.2-0.8-0.9-2.3-2.3-1.41.4-2.1-2.3
Social responses3.03.98.73.0-2.82.6-2.02.3-2.32.2-2.2-1.91.91.41.4-1.8-1.90.9-0.7-1.4-1.4
Social time1.62.13.71.8-1.21.5-0.31.8-1.91.9-1.9-1.71.8-0.3-0.1-1.8-1.8-0.70.4-1.4-1.5
Soleus weight2.47.013.53.7-2.83.1-1.53.3-3.43.2-3.1-3.13.10.50.9-3.1-3.2-0.1-0.1-2.5-2.1
Bone: stiffness1.72.74.32.0-1.91.7-0.82.1-1.91.9-2.0-2.02.00.70.4-1.9-2.00.2-0.1-1.9-1.6
Tibialis anterior weight0.20.63.00.5-0.7-0.2-1.70.3-0.1-0.50.2-0.10.11.21.10.1-0.11.4-1.1-0.00.7
Time to tail flick, vehicle, before self-admin1.61.64.01.7-2.01.9-1.71.2-1.00.7-0.9-0.80.81.71.4-0.6-0.71.1-1.4-0.8-0.5
Time to tail flick, vehicle, after self-admin0.30.40.80.6-0.70.7-0.30.7-0.70.7-0.8-0.70.70.2-0.2-0.7-0.7-0.10.1-0.8-0.9
Time to tail flick, test, before self-admin3.63.56.30.9-0.20.81.21.8-2.02.3-2.1-2.12.1-1.6-1.8-2.3-2.1-2.12.0-2.3-2.5
Time to tail flick, test, after self-admin1.31.33.41.8-1.81.5-1.31.2-1.11.2-0.9-0.80.81.41.2-0.8-0.91.1-0.7-0.7-0.5
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.10.2-0.10.1-0.30.10.10.10.1-0.1-0.2-0.10.00.10.00.30.30.1
Delta time to tail flick, test, before/after SA1.81.65.11.3-1.91.3-2.00.6-0.30.0-0.1-0.10.02.32.00.2-0.12.0-1.9-0.10.4
Tibia length1.43.96.22.4-1.92.1-0.82.5-2.42.5-2.4-2.42.40.20.1-2.4-2.4-0.30.3-2.0-2.0
Ambulatory time before self-admin0.30.31.30.20.20.60.60.2-0.50.7-0.5-0.40.4-0.9-0.6-0.4-0.5-1.20.5-0.2-0.7
Ambulatory time after self-admin0.91.03.20.10.50.21.80.3-0.61.3-0.9-0.60.7-1.5-1.2-0.7-0.6-1.61.4-0.4-1.1
Bone: tissue strength0.40.40.7-0.50.4-0.7-0.1-0.70.7-0.60.80.7-0.70.10.20.70.80.4-0.40.80.8
Total heroin consumption0.50.62.00.8-0.90.7-1.30.1-0.1-0.10.20.1-0.11.11.40.20.21.2-1.00.60.7
Bone: trabecular number0.71.13.60.6-1.0-0.1-1.7-0.00.3-0.70.60.5-0.51.81.70.50.31.9-1.80.51.1
Bone: trabecular spacing0.10.10.4-0.30.20.10.2-0.50.5-0.30.40.5-0.50.00.20.50.60.1-0.10.50.4
Bone: trabecular thickness2.63.17.72.6-2.82.4-2.41.6-1.41.1-1.1-1.11.12.32.3-1.0-1.21.9-2.0-0.7-0.2
Bone: trabecular tissue density1.11.63.11.1-0.81.00.51.3-1.51.8-1.7-1.41.4-0.4-0.7-1.5-1.5-0.90.8-1.5-1.7
Water consumed over 24 hours0.40.51.20.4-0.10.61.10.3-0.51.1-0.8-0.40.4-0.7-0.6-0.6-0.6-0.81.0-0.4-0.9
Number of responses in last shaping day0.60.61.30.30.10.30.20.8-0.80.6-0.7-1.11.0-0.7-0.7-1.1-0.8-1.10.5-1.0-0.9