Hub : Genes

Pds5b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr12_5174339_5174441 0.05 0.03 1.7e-03 0.04 0.02 0.01 0.03 3.3e-04 4.7e-03 2.4e-02 3.3e-03
2 OFC isoform ratio XM_039089328.1 0.29 0.15 2.6e-03 0.04 0.07 0.07 0.05 3.8e-02 8.3e-03 8.8e-03 2.7e-02
3 Brain mRNA stability Pds5b 0.09 0.05 4.8e-08 0.07 0.09 0.09 0.09 6.3e-07 6.9e-09 5.5e-09 2.1e-08
4 pVTA isoform ratio XM_039089328.1 0.04 0.03 6.1e-03 0 0.01 0.01 0.01 2.0e-01 2.1e-02 4.4e-02 6.1e-02
5 OFC intron excision ratio chr12_5174339_5176775 0.21 0.12 7.1e-03 0.04 0.04 0.04 0.04 4.4e-02 3.2e-02 3.3e-02 3.5e-02
6 Brain gene expression Pds5b 0.55 0.15 0.0e+00 0.4 0.43 0.44 0.43 3.9e-40 4.5e-44 2.7e-44 5.5e-44
7 PL gene expression Pds5b 0.49 0.14 0.0e+00 0.38 0.41 0.41 0.41 5.1e-44 6.2e-48 1.3e-47 5.8e-48
8 OFC gene expression Pds5b 0.79 0.1 2.8e-16 0.38 0.45 0.46 0.44 4.4e-10 3.6e-12 2.1e-12 8.8e-12
9 BLA gene expression Pds5b 0.44 0.15 4.8e-15 0.22 0.28 0.27 0.28 4.4e-12 6.7e-15 9.9e-15 4.1e-15
10 pVTA intron excision ratio chr12_5174339_5176775 0.05 0.04 1.7e-03 0.02 0.02 0.01 0.02 1.1e-02 1.4e-02 5.1e-02 1.2e-02
11 OFC isoform ratio XM_039089321.1 0.25 0.14 4.5e-03 0.1 0.04 0.04 0.07 2.1e-03 3.3e-02 3.3e-02 1.1e-02
12 Adipose mRNA stability Pds5b 0.05 0.03 1.6e-03 0.02 0.01 0.01 0.01 2.5e-03 1.4e-02 1.7e-02 1.1e-02
13 IL gene expression Pds5b 0.59 0.15 2.4e-11 0.41 0.49 0.51 0.49 4.3e-11 1.3e-13 3.1e-14 1.3e-13
14 NAcc intron excision ratio chr12_5174339_5176775 0.04 0.03 9.0e-05 0.03 0.03 0.03 0.03 9.0e-06 2.7e-05 3.9e-05 2.5e-05
15 LHb gene expression Pds5b 0.2 0.12 5.7e-03 0.1 0.04 0.01 0.07 2.7e-03 3.4e-02 1.5e-01 8.5e-03
16 NAcc isoform ratio XM_039089328.1 0.03 0.02 1.9e-03 0.02 0.02 0.02 0.02 1.6e-04 8.9e-04 8.1e-04 6.2e-04
17 NAcc gene expression Pds5b 0.43 0.14 0.0e+00 0.25 0.34 0.34 0.34 8.2e-38 1.4e-53 1.7e-53 1.9e-53
18 pVTA gene expression Pds5b 0.34 0.13 0.0e+00 0.26 0.24 0.25 0.25 1.6e-20 1.4e-19 2.2e-20 8.7e-20
19 IC gene expression Pds5b 0.62 0.12 0.0e+00 0.42 0.41 0.41 0.39 4.6e-19 2.6e-18 2.2e-18 2.3e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.11.86.3-2.32.50.71.71.81.41.31.31.11.1-1.2-1.21.3-0.80.8-0.81.30.70.7
Area under the delay curve1.41.75.71.1-2.41.1-1.6-2.1-0.4-0.3-0.5-0.1-2.22.22.2-0.7-0.30.3-0.3-0.70.30.3
BMI with tail1.44.88.1-1.90.72.5-0.3-0.42.82.72.62.7-1.11.11.12.4-2.62.6-2.62.42.72.7
BMI without tail1.34.012.3-3.20.73.50.5-0.12.22.11.82.1-1.61.61.61.4-2.22.2-2.21.32.22.2
Body weight4.318.955.0-7.42.67.21.90.65.04.64.24.7-2.62.62.63.4-4.74.7-4.73.24.74.7
Weight adjusted by age0.30.41.6-0.71.20.00.91.00.50.40.50.40.9-0.9-0.90.5-0.20.2-0.20.50.20.2
Bone surface1.22.25.7-2.41.61.91.00.81.91.71.71.7-0.10.10.11.5-1.51.5-1.51.51.51.5
Bone volume0.91.73.1-1.51.61.00.70.81.81.71.71.60.3-0.3-0.31.6-1.31.3-1.31.61.31.3
Breakpoint value in progressive ratio session0.30.41.2-0.1-1.00.9-0.3-0.7-0.4-0.3-0.5-0.2-1.11.11.1-0.6-0.00.0-0.0-0.7-0.0-0.0
Number of licking bursts0.40.72.6-1.21.6-0.31.41.40.10.10.1-0.01.1-1.1-1.10.20.2-0.20.20.2-0.2-0.2
Context. condit. distance diff. score0.60.74.5-2.10.21.81.00.2-0.1-0.4-0.4-0.3-1.00.90.9-0.70.1-0.10.1-0.70.10.1
Locomotion velocity, session 10.40.40.90.9-1.0-0.1-0.5-0.6-0.8-0.6-0.8-0.5-0.60.60.6-0.80.4-0.40.4-0.8-0.5-0.5
Locomotion distance, session 10.81.01.81.3-0.8-1.1-0.3-0.2-1.3-1.3-1.2-1.30.0-0.0-0.0-1.11.2-1.21.2-1.1-1.1-1.1
Locomotion velocity, session 20.30.30.80.4-0.6-0.0-0.1-0.3-0.8-0.7-0.8-0.6-0.40.40.4-0.90.5-0.50.5-0.9-0.6-0.6
Locomotion distance, session 22.43.45.70.8-0.2-1.70.80.7-2.4-2.4-2.3-2.40.8-0.8-0.8-2.12.3-2.32.3-2.1-2.3-2.3
Locomotion velocity, session 30.10.10.3-0.5-0.20.60.1-0.2-0.1-0.2-0.2-0.1-0.50.50.5-0.30.0-0.00.0-0.30.00.0
Locomotion distance, session 30.50.61.0-0.30.8-0.90.80.9-0.5-0.6-0.5-0.71.0-1.0-1.0-0.40.8-0.80.8-0.3-0.8-0.8
Stereotopy head waving bouts, day 30.70.83.0-1.71.60.91.21.10.90.90.80.80.5-0.5-0.50.8-0.60.6-0.60.70.60.6
Stereotopy head waving duration, day 30.20.20.50.20.20.1-0.2-0.00.60.70.70.70.1-0.1-0.10.7-0.60.6-0.60.70.50.5
Locomotion velocity, session 71.11.24.31.2-2.10.9-1.4-1.8-0.4-0.2-0.4-0.1-1.71.71.7-0.6-0.30.3-0.3-0.60.20.2
Locomotion distance, session 70.91.12.60.4-1.10.20.0-0.4-1.4-1.4-1.5-1.3-0.70.70.7-1.61.1-1.11.1-1.6-1.0-1.0
Stereotopy head waving bouts, day 70.30.30.60.3-0.3-0.40.10.0-0.8-0.8-0.8-0.70.1-0.1-0.1-0.70.7-0.70.7-0.7-0.7-0.7
Stereotopy head waving duration, day 70.20.20.50.7-0.6-0.5-0.4-0.4-0.5-0.4-0.5-0.4-0.10.10.1-0.40.4-0.40.4-0.4-0.4-0.4
Locomotion velocity, session 80.30.31.2-0.1-0.70.9-0.4-0.70.0-0.1-0.1-0.0-1.11.11.1-0.2-0.10.1-0.1-0.20.40.4
Locomotion distance, session 80.20.41.4-1.2-0.11.20.5-0.0-0.2-0.5-0.4-0.4-0.90.80.8-0.60.3-0.30.3-0.60.00.0
Degree of sensitization distance0.70.72.01.1-1.40.1-0.7-0.9-1.0-0.9-1.0-0.8-0.80.90.9-1.10.5-0.50.5-1.1-0.6-0.6
Degree of sensitization stereotypy0.20.20.60.7-0.8-0.3-0.4-0.5-0.6-0.5-0.6-0.5-0.30.30.3-0.60.4-0.40.4-0.6-0.4-0.4
Conditioned locomotion0.20.20.4-0.10.6-0.40.20.40.40.40.50.40.6-0.6-0.60.5-0.20.2-0.20.60.20.2
Cocaine response after cond. corrected4.14.98.10.4-0.31.0-1.9-1.42.82.82.82.8-0.80.80.82.8-2.72.7-2.72.82.72.7
Cocaine response after cond. not corrected3.13.65.30.4-0.71.2-1.8-1.62.22.32.22.3-1.21.21.22.1-2.32.3-2.32.12.32.3
Cocaine response before conditioning1.31.53.7-0.4-0.60.30.70.1-1.7-1.7-1.8-1.6-0.50.50.5-1.91.3-1.31.3-1.9-1.3-1.3
Saline control response2.53.49.5-2.82.10.03.12.6-1.4-1.6-1.6-1.61.4-1.4-1.4-1.71.7-1.71.7-1.7-1.7-1.7
Bone: connectivity density1.21.89.0-3.02.41.52.11.81.21.11.01.00.6-0.6-0.60.8-0.70.7-0.70.80.70.7
Bone: cortical apparent density0.40.51.60.7-1.30.4-1.2-1.20.10.10.10.2-1.11.11.10.1-0.40.4-0.40.10.50.5
Bone: cortical area0.81.25.4-1.3-0.62.3-0.1-0.70.60.50.30.6-1.71.71.70.0-0.90.9-0.9-0.11.01.0
Bone: cortical porosity0.20.20.4-0.40.6-0.40.50.6-0.1-0.3-0.1-0.40.6-0.6-0.6-0.10.5-0.50.5-0.0-0.3-0.3
Bone: cortical porosity0.40.40.70.10.1-0.60.40.4-0.7-0.8-0.7-0.80.5-0.4-0.4-0.60.9-0.90.9-0.6-0.7-0.7
Bone: cortical thickness0.60.94.3-1.3-0.32.10.0-0.50.60.50.40.6-1.41.41.40.1-0.80.8-0.80.10.90.9
Bone: cortical thickness0.30.41.9-1.40.21.00.90.4-0.4-0.5-0.6-0.5-0.40.40.4-0.70.3-0.30.3-0.8-0.2-0.2
Bone: cortical tissue density0.30.41.30.8-1.20.3-1.1-1.10.10.10.10.2-0.91.01.00.1-0.40.4-0.40.10.40.4
Condit. Reinf. active minus inactive responses0.30.41.40.7-1.20.0-1.1-1.1-0.0-0.0-0.00.0-0.80.80.8-0.0-0.10.1-0.1-0.00.30.3
Condit. Reinf. active-inactive response ratio0.60.71.90.5-1.30.6-1.3-1.40.30.30.30.4-1.21.21.20.2-0.50.5-0.50.20.70.7
Condit. Reinf. active responses0.50.61.20.3-0.8-0.4-0.2-0.4-1.0-1.1-1.0-1.0-0.30.30.3-1.00.9-0.90.9-1.0-0.7-0.7
Condit. Reinf. inactive responses1.92.34.20.3-0.2-1.10.70.6-2.0-2.0-1.9-2.00.5-0.5-0.5-1.91.9-1.91.9-1.8-1.9-1.9
Incentive salience index mean0.30.40.70.5-0.8-0.4-0.4-0.5-0.7-0.8-0.7-0.8-0.30.30.3-0.70.7-0.70.7-0.7-0.5-0.5
Condit. Reinf. lever presses0.50.71.30.4-0.4-0.70.10.0-1.1-1.2-1.1-1.10.1-0.1-0.1-1.01.0-1.01.0-1.0-1.0-1.0
Condit. Reinf. active minus inactive responses0.70.92.2-1.2-0.61.50.6-0.2-0.9-0.9-1.1-0.7-1.31.31.3-1.40.4-0.40.4-1.4-0.4-0.4
Condit. Reinf. active-inactive response ratio0.70.81.8-0.6-0.81.10.3-0.4-1.0-0.9-1.1-0.8-1.21.11.1-1.30.5-0.50.5-1.4-0.5-0.5
Condit. Reinf. active responses0.81.12.6-1.3-0.61.60.7-0.2-1.0-1.0-1.3-0.9-1.31.31.3-1.50.6-0.60.6-1.6-0.6-0.6
Condit. Reinf. inactive responses0.10.20.5-0.70.20.50.60.3-0.4-0.5-0.5-0.4-0.10.10.1-0.60.4-0.40.4-0.7-0.4-0.4
Condit. Reinf. lever presses0.20.30.8-0.2-0.50.50.2-0.2-0.7-0.7-0.8-0.6-0.60.60.6-0.90.4-0.40.4-0.9-0.4-0.4
Condit. Reinf. lever reinforcers received0.91.33.3-0.9-0.81.30.6-0.2-1.3-1.3-1.5-1.2-1.21.21.2-1.80.8-0.80.8-1.8-0.8-0.8
Conditioned reinforcement - actives0.50.86.4-2.51.21.21.71.2-0.1-0.2-0.3-0.20.2-0.2-0.2-0.50.2-0.20.2-0.6-0.2-0.2
Conditioned reinforcement - inactives0.50.71.9-1.01.4-0.61.31.4-0.2-0.3-0.2-0.41.3-1.3-1.3-0.10.6-0.60.6-0.1-0.6-0.6
Conditioned locomotion0.50.75.1-2.30.81.31.50.9-0.3-0.4-0.5-0.4-0.20.20.2-0.70.3-0.30.3-0.8-0.3-0.3
Patch foraging indifference point 0 sec0.71.44.5-0.32.0-1.51.21.70.20.10.4-0.02.1-2.1-2.10.60.5-0.50.50.7-0.5-0.5
Patch foraging indifference point AUC0.40.52.4-1.61.30.21.41.2-0.0-0.1-0.1-0.20.7-0.7-0.7-0.10.3-0.30.3-0.1-0.3-0.3
Delay disc. indifference point, 0s delay6.87.510.40.3-2.43.1-2.7-3.12.42.52.22.7-3.23.23.21.8-3.13.1-3.11.63.13.1
Delay disc. indifference point, 16s delay0.50.61.20.5-1.10.2-0.4-0.7-0.9-0.8-0.9-0.7-0.90.90.9-1.00.5-0.50.5-1.0-0.5-0.5
Delay disc. indifference point, 2s delay3.23.610.91.9-3.31.4-2.8-3.20.20.40.20.6-3.03.03.0-0.0-1.21.2-1.2-0.11.21.2
Delay disc. indifference point, 24s delay0.30.41.40.9-1.20.1-0.8-0.9-0.5-0.4-0.5-0.4-0.80.80.8-0.50.2-0.20.2-0.5-0.2-0.2
Delay disc. indifference point, 4s delay1.92.05.21.2-2.31.2-2.0-2.30.40.60.30.7-2.22.22.20.2-1.11.1-1.10.11.11.1
Delay disc. indifference point, 8s delay0.70.81.60.5-1.10.1-0.2-0.6-1.2-1.1-1.2-1.0-0.90.90.9-1.30.8-0.80.8-1.3-0.8-0.8
Indifference point function ln k0.71.21.8-0.30.6-0.81.11.0-1.2-1.2-1.2-1.30.9-0.9-0.9-1.11.3-1.31.3-1.1-1.3-1.3
Indifference point function log k0.71.21.8-0.30.6-0.81.11.0-1.2-1.2-1.2-1.30.9-0.9-0.9-1.11.3-1.31.3-1.1-1.3-1.3
Patch foraging total patch changes 0 sec1.12.06.6-0.42.3-1.91.52.10.0-0.10.2-0.32.5-2.6-2.60.50.8-0.80.80.6-0.8-0.8
Patch foraging total patch changes 12 sec0.50.72.3-0.61.5-0.50.81.20.70.60.70.51.2-1.2-1.20.8-0.20.2-0.20.90.20.2
Patch foraging total patch changes 18 sec1.01.54.7-0.62.2-1.31.31.80.50.40.60.22.1-2.1-2.10.80.2-0.20.20.9-0.2-0.2
Patch foraging total patch changes 24 sec2.13.66.4-0.72.2-1.92.32.5-1.4-1.5-1.2-1.62.5-2.5-2.5-1.01.9-1.91.9-0.9-1.9-1.9
Patch foraging total patch changes 6 sec1.11.65.1-1.02.3-1.31.62.00.20.00.3-0.12.2-2.2-2.20.40.5-0.50.50.5-0.5-0.5
Patch foraging time to switch 0 sec5.511.318.92.5-2.91.8-4.3-3.93.23.43.23.5-3.03.03.03.1-3.73.7-3.73.13.73.7
Patch foraging water rate 0 sec3.77.717.9-2.93.6-1.44.24.1-1.9-2.1-1.9-2.33.2-3.2-3.2-1.82.7-2.72.7-1.7-2.7-2.7
Patch foraging water rate 12 sec1.53.24.7-1.01.4-1.02.22.0-1.8-1.9-1.8-1.91.6-1.6-1.6-1.72.0-2.02.0-1.7-2.0-2.0
Patch foraging water rate 18 sec2.13.25.8-0.3-0.0-0.71.30.9-2.3-2.3-2.4-2.30.5-0.4-0.4-2.42.2-2.22.2-2.4-2.2-2.2
Patch foraging water rate 24 sec1.72.46.9-2.21.90.02.62.2-1.1-1.3-1.3-1.31.3-1.3-1.3-1.31.5-1.51.5-1.3-1.5-1.5
Patch foraging water rate 6 sec1.31.93.7-1.11.4-0.71.91.8-1.3-1.3-1.3-1.41.3-1.3-1.3-1.21.5-1.51.5-1.2-1.5-1.5
Seeking ratio, delayed vs. immediate footshock0.60.83.21.50.5-1.8-0.50.30.50.50.70.41.3-1.3-1.31.0-0.10.1-0.11.00.10.1
Distance traveled before self-admin0.30.31.30.8-1.10.2-0.9-1.0-0.3-0.2-0.3-0.1-0.90.90.9-0.3-0.10.1-0.1-0.3-0.0-0.0
Distance traveled after self-admin1.01.22.1-0.0-0.1-0.60.70.5-1.4-1.4-1.4-1.40.4-0.3-0.3-1.41.3-1.31.3-1.5-1.3-1.3
Extensor digitorum longus weight0.83.325.1-5.01.83.82.41.31.21.00.71.1-1.01.01.00.2-1.21.2-1.2-0.01.11.1
Bone: elastic displacement0.10.10.5-0.70.60.00.60.6-0.0-0.3-0.1-0.30.3-0.3-0.3-0.10.4-0.40.4-0.1-0.1-0.1
Bone: elastic work0.60.85.9-2.41.61.11.61.30.50.30.40.30.3-0.3-0.30.2-0.20.2-0.20.20.30.3
Bone: endosteal estimation0.51.14.0-1.52.0-0.21.91.90.0-0.10.0-0.21.5-1.4-1.40.00.4-0.40.40.0-0.5-0.5
Bone: endosteal perimeter0.30.72.3-1.41.00.41.51.2-0.6-0.6-0.7-0.60.5-0.5-0.5-0.80.7-0.70.7-0.8-0.7-0.7
Epididymis fat weight0.00.20.3-0.2-0.0-0.00.30.2-0.5-0.5-0.5-0.5-0.0-0.0-0.0-0.60.4-0.40.4-0.6-0.5-0.5
Delta time in closed arm before/after self-admin0.30.31.1-0.5-0.61.00.0-0.4-0.3-0.3-0.4-0.2-1.00.90.9-0.6-0.00.0-0.0-0.60.10.1
Delta time in open arm before/after self-admin0.70.74.32.1-0.7-1.7-0.9-0.5-0.7-0.6-0.5-0.60.5-0.5-0.5-0.30.6-0.60.6-0.2-0.7-0.7
Diff in mean of infusions in LGA sessions0.20.20.4-0.50.3-0.00.70.5-0.5-0.5-0.5-0.50.3-0.3-0.3-0.60.5-0.50.5-0.6-0.6-0.6
Delay discount exponential model param1.61.86.3-1.32.5-0.81.62.00.80.70.90.52.2-2.2-2.21.0-0.00.0-0.01.10.00.0
Extinction: sum of active levers before priming0.20.20.60.6-0.8-0.1-0.5-0.6-0.5-0.5-0.5-0.4-0.40.40.4-0.50.3-0.30.3-0.5-0.3-0.3
Active lever presses in extinction session 60.10.10.3-0.30.4-0.20.50.5-0.2-0.2-0.2-0.20.5-0.5-0.5-0.20.3-0.30.3-0.2-0.3-0.3
Bone: final force0.50.84.0-2.00.52.00.80.20.70.60.50.6-0.80.80.80.2-0.70.7-0.70.10.80.8
Bone: final moment0.40.63.0-1.70.51.70.70.30.60.50.40.5-0.60.60.60.2-0.60.6-0.60.20.70.7
Food consumed during 24 hour testing period0.50.72.1-0.71.5-0.70.91.20.40.40.50.21.4-1.4-1.40.60.1-0.10.10.6-0.1-0.1
Glucose0.60.95.12.3-1.8-0.3-1.6-1.5-0.5-0.4-0.4-0.3-0.91.01.0-0.40.1-0.10.1-0.30.00.0
Heart weight1.01.53.0-1.10.20.21.30.8-1.5-1.5-1.6-1.50.1-0.1-0.1-1.71.4-1.41.4-1.7-1.4-1.4
Delay discount hyperbolic model param1.61.76.2-1.32.5-1.01.62.10.60.40.70.32.2-2.2-2.20.80.2-0.20.20.9-0.2-0.2
Intermittent access intake day 1-15 change0.51.03.3-1.41.8-0.41.61.7-0.0-0.10.0-0.21.5-1.5-1.50.00.5-0.50.50.1-0.5-0.5
Intermittent access intake escalation0.40.82.9-1.41.7-0.31.41.50.10.00.1-0.11.3-1.3-1.30.20.3-0.30.30.2-0.3-0.3
Intermittent access intake escalation 20.40.51.4-0.20.9-0.90.71.0-0.2-0.3-0.1-0.31.2-1.2-1.2-0.00.5-0.50.50.0-0.5-0.5
Intermitt. access day 1 inactive lever presses0.10.51.5-0.71.2-0.60.91.10.10.00.2-0.01.2-1.2-1.20.20.3-0.30.30.3-0.3-0.3
Intermitt. access day 15 inactive lever presses1.43.06.00.8-0.10.2-1.6-1.02.22.22.32.2-0.40.40.42.4-2.02.0-2.02.52.02.0
Intermitt. access escalation Index0.20.30.80.2-0.4-0.10.1-0.0-0.8-0.8-0.9-0.8-0.20.20.2-0.90.6-0.60.6-0.9-0.6-0.6
Intermittent access day 1 total infusions0.50.92.00.4-0.9-0.2-0.0-0.3-1.3-1.2-1.3-1.2-0.40.40.4-1.41.0-1.01.0-1.4-1.0-1.0
Intermittent access day 15 total infusions0.50.81.3-0.60.3-0.30.90.7-1.1-1.1-1.1-1.10.4-0.4-0.4-1.11.0-1.01.0-1.1-1.0-1.0
Intermittent access terminal intake (last 3 days)0.20.30.6-0.2-0.1-0.20.40.2-0.7-0.7-0.7-0.70.1-0.1-0.1-0.70.6-0.60.6-0.8-0.6-0.6
Intermittent access total infusions0.30.30.90.2-0.90.5-0.4-0.7-0.5-0.5-0.6-0.4-0.80.80.8-0.70.2-0.20.2-0.7-0.2-0.2
Intermittent access day 1 locomotion0.50.61.80.7-1.30.2-0.6-0.9-0.8-0.8-0.9-0.7-0.90.90.9-0.90.4-0.40.4-1.0-0.4-0.4
Intermittent access day 15 total locomotion0.81.52.5-1.00.4-0.11.41.0-1.4-1.5-1.5-1.40.5-0.5-0.5-1.61.4-1.41.4-1.6-1.4-1.4
Intermittent access total locomotion0.50.61.50.1-0.80.10.0-0.3-1.1-1.0-1.1-1.0-0.50.50.5-1.20.7-0.70.7-1.2-0.7-0.7
Intermittent access standard deviation0.71.43.6-0.10.9-0.0-0.40.11.71.61.71.50.5-0.5-0.51.8-1.31.3-1.31.91.31.3
Left kidney weight2.310.745.9-6.83.74.93.02.13.73.43.23.3-0.50.50.52.6-3.13.1-3.12.53.03.0
Right kidney weight2.210.134.9-5.93.14.72.21.53.83.53.33.5-0.80.80.82.8-3.33.3-3.32.63.23.2
Cocaine induced anxiety0.20.31.20.3-1.10.5-0.6-0.9-0.3-0.2-0.3-0.1-1.01.01.0-0.4-0.10.1-0.1-0.50.10.1
Post-drug Anxiety4.44.712.32.5-3.41.2-3.5-3.50.91.10.91.3-3.03.03.00.8-1.71.7-1.70.81.71.7
Baseline Anxiety3.44.010.12.5-2.40.6-3.2-2.91.41.61.51.7-2.12.12.11.5-1.91.9-1.91.61.91.9
Tail length1.55.736.9-6.12.05.02.61.31.81.71.21.7-1.51.51.50.6-1.91.9-1.90.41.71.7
Length with tail3.415.081.7-9.03.47.33.72.03.73.32.83.4-2.12.12.11.9-3.53.5-3.51.63.33.3
Length without tail3.310.537.4-6.13.34.62.31.73.93.63.43.5-0.60.60.62.9-3.33.3-3.32.83.23.2
Times rat made contact with spout0.10.21.2-1.10.20.90.60.2-0.0-0.1-0.2-0.1-0.40.40.4-0.3-0.00.0-0.0-0.40.00.0
Lifetime Intake0.20.31.10.5-1.10.3-0.7-0.9-0.2-0.2-0.2-0.1-0.90.90.9-0.3-0.10.1-0.1-0.30.10.1
Liver weight, left1.82.911.7-2.73.4-0.02.52.71.20.91.20.82.2-2.2-2.21.3-0.30.3-0.31.30.30.3
Liver weight, right1.12.04.8-2.21.41.60.70.61.81.71.71.6-0.10.10.11.5-1.51.5-1.51.51.51.5
Locomotor activity1.93.05.9-2.40.71.02.31.4-1.9-2.0-2.1-1.9-0.10.10.1-2.41.7-1.71.7-2.4-1.7-1.7
Locomotor testing distance0.71.33.4-1.51.3-0.11.81.6-0.9-1.0-0.9-1.01.0-0.9-0.9-1.01.1-1.11.1-0.9-1.1-1.1
Locomotor testing rearing0.30.71.9-0.01.1-1.10.91.2-0.3-0.3-0.2-0.41.4-1.3-1.3-0.10.6-0.60.6-0.0-0.7-0.7
Locomotion in novel chamber0.60.83.3-1.81.10.31.61.3-0.6-0.7-0.7-0.70.6-0.6-0.6-0.80.8-0.80.8-0.7-0.7-0.7
Locomotion in novel chamber post-restriction1.42.24.4-2.10.90.52.11.4-1.6-1.6-1.7-1.60.3-0.3-0.3-1.91.6-1.61.6-1.9-1.6-1.6
Fecal boli incidents, locomotor time 10.40.62.7-1.60.41.01.20.7-0.6-0.6-0.8-0.6-0.30.30.3-0.90.5-0.50.5-0.9-0.5-0.5
Change in fecal boli incidents, locomotor task0.90.91.50.6-0.30.1-1.0-0.71.21.21.21.2-0.20.20.21.2-1.11.1-1.11.21.11.1
Time >=10cm from walls, locomotor time 11.41.54.41.7-2.10.4-2.1-2.10.30.40.30.5-1.61.61.60.3-0.80.8-0.80.20.80.8
Bouts of movement, locomotor time 10.30.42.5-1.60.80.71.20.9-0.2-0.3-0.3-0.30.1-0.1-0.1-0.40.3-0.30.3-0.4-0.3-0.3
Total resting periods, locomotor time 10.30.42.3-1.50.70.71.10.8-0.3-0.4-0.4-0.4-0.00.00.0-0.60.3-0.30.3-0.6-0.3-0.3
Rest time, locomotor task time 10.30.41.6-1.30.41.20.40.10.70.60.50.6-0.40.40.40.4-0.70.7-0.70.30.70.7
Distance moved, locomotor task time 10.50.71.40.7-0.7-0.5-0.1-0.2-1.2-1.1-1.1-1.1-0.20.20.2-1.11.0-1.01.0-1.1-1.0-1.0
Vertical activity count, locomotor time 10.71.73.0-0.40.1-0.41.10.7-1.7-1.7-1.7-1.70.3-0.3-0.3-1.71.6-1.61.6-1.7-1.6-1.6
Time >=10cm from walls, locomotor time 22.13.04.10.0-1.42.0-1.7-1.91.61.71.41.8-2.02.02.01.2-2.02.0-2.01.12.02.0
Bouts of movement, locomotor time 20.20.31.9-1.40.70.61.00.7-0.2-0.2-0.3-0.30.1-0.1-0.1-0.40.3-0.30.3-0.4-0.3-0.3
Total resting periods, locomotor time 20.10.21.7-1.30.80.50.90.70.10.10.00.00.2-0.2-0.2-0.0-0.00.0-0.0-0.00.00.0
Rest time, locomotor task time 20.00.00.30.5-0.3-0.2-0.4-0.30.00.00.00.0-0.10.10.10.1-0.10.1-0.10.10.10.1
Distance moved, locomotor task time 20.20.20.4-0.50.6-0.20.70.6-0.3-0.3-0.3-0.30.5-0.5-0.5-0.30.4-0.40.4-0.3-0.4-0.4
Vertical activity count, locomotor time 20.71.03.5-1.91.40.21.81.5-0.5-0.6-0.6-0.70.9-0.9-0.9-0.70.8-0.80.8-0.6-0.8-0.8
Light reinforcement 10.51.34.21.6-2.00.0-1.2-1.5-1.2-1.1-1.2-1.0-1.31.31.3-1.20.6-0.60.6-1.2-0.5-0.5
Light reinforcement 20.10.10.40.60.0-0.6-0.10.1-0.2-0.2-0.1-0.20.3-0.3-0.3-0.00.3-0.30.30.0-0.2-0.2
Bone: marrow area0.51.14.1-1.42.0-0.31.91.9-0.0-0.1-0.0-0.21.5-1.5-1.50.00.5-0.50.50.0-0.5-0.5
Bone: maximum diameter0.30.62.3-1.50.61.40.60.30.90.80.70.8-0.40.40.40.5-0.80.8-0.80.50.80.8
Bone: maximum force0.30.53.6-1.90.81.51.10.70.30.20.10.2-0.30.30.3-0.1-0.20.2-0.2-0.10.30.3
Bone: maximum moment0.20.42.8-1.70.91.21.10.70.20.10.10.1-0.10.10.1-0.1-0.10.1-0.1-0.10.20.2
Mean time between licks in bursts0.40.92.61.4-0.2-1.6-0.20.1-1.0-1.0-0.8-1.00.9-0.9-0.9-0.61.1-1.11.1-0.6-1.1-1.1
Mean num. licks in bursts0.10.20.60.3-0.80.5-0.6-0.70.00.1-0.00.1-0.70.80.8-0.1-0.30.3-0.3-0.10.30.3
Cd content in liver2.93.26.2-0.2-0.2-0.61.30.8-2.4-2.4-2.4-2.30.4-0.3-0.3-2.52.2-2.22.2-2.5-2.2-2.2
Co content in liver1.61.95.8-1.02.4-1.41.82.20.1-0.10.2-0.22.4-2.4-2.40.40.7-0.70.70.4-0.7-0.7
Cu content in liver0.20.20.40.50.2-0.60.30.4-0.5-0.4-0.4-0.50.5-0.5-0.5-0.30.5-0.50.5-0.3-0.5-0.5
Fe content in liver0.60.81.9-0.70.00.41.00.5-1.1-1.1-1.2-1.0-0.10.10.1-1.30.9-0.90.9-1.4-0.9-0.9
K content in liver0.70.60.80.3-0.60.7-0.9-0.90.80.80.70.8-0.90.90.90.7-0.90.9-0.90.70.90.9
Mg content in liver0.60.61.1-0.60.20.8-0.2-0.21.01.01.01.0-0.40.40.40.9-1.01.0-1.00.91.01.0
Mn content in liver0.10.10.40.40.1-0.4-0.4-0.10.40.40.50.40.3-0.3-0.30.6-0.30.3-0.30.60.30.3
Na content in liver0.60.61.3-0.80.01.2-0.1-0.30.80.70.70.8-0.90.90.90.6-0.90.9-0.90.60.90.9
Rb content in liver0.70.83.71.9-1.3-1.2-1.1-0.9-0.9-0.8-0.8-0.8-0.0-0.0-0.0-0.60.7-0.70.7-0.6-0.7-0.7
Se content in liver3.03.66.70.1-1.72.5-1.7-2.11.51.51.31.7-2.62.62.61.0-2.02.0-2.00.92.02.0
Sr content in liver0.40.41.5-0.61.2-0.40.81.00.30.30.40.21.0-1.0-1.00.40.0-0.00.00.5-0.0-0.0
Zn content in liver1.21.35.4-2.22.30.51.81.80.90.70.80.61.2-1.2-1.20.8-0.30.3-0.30.80.30.3
Bone: minimum diameter0.00.10.10.30.1-0.20.20.2-0.3-0.3-0.3-0.30.2-0.2-0.2-0.30.3-0.30.3-0.3-0.3-0.3
Time in familiar zone, hab. session 11.01.02.40.60.6-0.6-0.50.11.31.31.41.20.8-0.8-0.81.5-0.90.9-0.91.60.90.9
Time in novel zone, hab. session 10.20.20.8-0.7-0.40.90.1-0.3-0.3-0.3-0.4-0.2-0.80.80.8-0.50.0-0.00.0-0.5-0.0-0.0
Total zone transitions, hab. session 11.42.03.71.1-1.2-0.9-0.2-0.4-1.9-1.9-1.9-1.8-0.30.20.2-1.91.6-1.61.6-1.8-1.6-1.6
Total locomotion distance, hab. session 10.40.61.71.0-1.3-0.1-0.8-0.9-0.8-0.8-0.8-0.7-0.80.80.8-0.80.5-0.50.5-0.8-0.4-0.4
Locomotion velocity, hab. session 10.81.22.71.5-1.6-0.4-0.9-1.0-1.3-1.3-1.3-1.2-0.80.80.8-1.30.9-0.90.9-1.2-0.8-0.8
Time in familiar zone, hab. session 21.21.21.90.5-0.40.6-1.1-0.91.31.41.31.4-0.60.50.51.3-1.31.3-1.31.31.31.3
Time in novel zone, hab. session 21.11.22.10.1-0.2-0.70.50.4-1.4-1.5-1.4-1.40.3-0.2-0.2-1.41.3-1.31.3-1.4-1.3-1.3
Total zone transitions, hab. session 20.30.30.6-0.60.20.10.70.4-0.7-0.7-0.8-0.70.0-0.0-0.0-0.80.6-0.60.6-0.8-0.6-0.6
Total locomotion distance, hab. session 20.40.50.90.3-0.3-0.30.20.0-1.0-0.9-1.0-0.9-0.10.10.1-1.00.8-0.80.8-0.9-0.8-0.8
Locomotion velocity, hab. session 20.40.51.00.2-0.3-0.40.30.1-1.0-1.0-1.0-1.0-0.0-0.0-0.0-1.00.9-0.90.9-1.0-0.9-0.9
Novel to familiar place preference ratio0.20.20.40.0-0.2-0.10.20.0-0.6-0.6-0.6-0.5-0.10.10.1-0.60.5-0.50.5-0.6-0.5-0.5
Novelty place preference0.20.20.50.3-0.4-0.30.0-0.1-0.7-0.7-0.7-0.6-0.10.10.1-0.70.5-0.50.5-0.7-0.6-0.6
Time in novel zone, NPP test0.10.20.30.1-0.3-0.10.0-0.1-0.6-0.5-0.6-0.5-0.10.10.1-0.60.4-0.40.4-0.6-0.5-0.5
Total zone transitions, NPP test0.30.40.9-0.3-0.20.10.40.1-0.8-0.8-0.9-0.8-0.20.20.2-0.90.7-0.70.7-0.9-0.7-0.7
Total locomotion distance, NPP test0.50.71.50.2-1.20.5-0.4-0.8-0.9-0.9-1.0-0.8-1.11.11.1-1.10.5-0.50.5-1.2-0.5-0.5
Locomotion velocity, NPP test0.91.22.9-0.1-0.90.30.2-0.3-1.5-1.5-1.6-1.4-0.80.80.8-1.71.1-1.11.1-1.7-1.1-1.1
Intraocular pressure0.40.63.0-1.71.30.51.51.3-0.2-0.4-0.3-0.40.4-0.4-0.4-0.40.4-0.40.4-0.3-0.3-0.3
Delta distance traveled before/after self-admin1.51.52.5-0.71.3-1.11.51.6-1.0-1.1-0.9-1.21.6-1.5-1.5-0.91.3-1.31.3-0.8-1.2-1.2
Delta ambulatory time before/after self-admin1.01.22.20.20.8-1.40.91.1-1.0-1.0-0.9-1.11.5-1.4-1.4-0.71.3-1.31.3-0.7-1.1-1.1
Parametrial fat weight1.73.96.50.3-0.81.3-1.9-1.62.32.22.32.3-1.41.41.42.2-2.42.4-2.42.22.52.5
Pavlov. Cond. lever latency0.81.03.1-1.71.41.01.00.91.21.11.11.00.3-0.3-0.31.0-0.90.9-0.90.90.80.8
Pavlov. Cond. magazine entry latency0.20.20.5-0.5-0.20.60.4-0.0-0.5-0.6-0.6-0.5-0.40.40.4-0.70.4-0.40.4-0.7-0.2-0.2
Pavlov. Cond. change in total contacts1.01.13.51.0-1.90.8-1.6-1.80.0-0.0-0.00.1-1.61.61.6-0.1-0.40.4-0.4-0.10.60.6
Pavlov. Cond. index score0.20.20.90.5-0.90.2-0.5-0.7-0.4-0.4-0.4-0.4-0.70.70.7-0.50.2-0.20.2-0.5-0.1-0.1
Pavlov. Cond. latency score0.30.41.50.8-1.20.1-0.7-0.9-0.6-0.6-0.6-0.5-0.80.80.8-0.60.3-0.30.3-0.6-0.2-0.2
Pavlov. Cond. lever contacts0.60.72.91.7-1.5-0.6-1.2-1.2-0.8-0.7-0.7-0.7-0.60.60.6-0.60.5-0.50.5-0.6-0.4-0.4
Pavlov. Cond. magazine entry number0.30.40.90.40.4-0.6-0.40.10.70.80.80.70.5-0.5-0.50.9-0.60.6-0.61.00.40.4
Pavlov. Cond. intertrial magazine entries0.60.71.90.80.0-1.40.10.3-0.9-0.9-0.7-1.00.8-0.8-0.8-0.61.0-1.01.0-0.5-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.90.5-0.90.3-0.7-0.8-0.1-0.1-0.2-0.1-0.70.70.7-0.2-0.10.1-0.1-0.20.20.2
Pavlov. Cond. response bias0.20.30.7-0.1-0.50.40.1-0.2-0.7-0.7-0.7-0.7-0.50.50.5-0.80.5-0.50.5-0.8-0.4-0.4
Pavlov. Cond. lever latency0.71.02.0-0.51.2-0.30.20.61.21.21.31.11.0-1.0-1.01.4-0.80.8-0.81.40.80.8
Pavlov. Cond. magazine entry latency1.21.55.51.6-2.30.3-1.5-1.8-0.9-0.8-1.0-0.7-1.71.71.7-1.00.3-0.30.3-1.1-0.3-0.3
Pavlov. Cond. change in total contacts1.01.53.40.4-0.8-0.10.3-0.1-1.7-1.7-1.8-1.6-0.50.50.5-1.81.4-1.41.4-1.8-1.4-1.4
Pavlov. Cond. index score1.31.73.31.1-1.6-0.1-0.5-0.9-1.7-1.6-1.8-1.5-1.01.01.0-1.81.2-1.21.2-1.8-1.2-1.2
Pavlov. Cond. latency score1.01.42.91.1-1.70.0-0.6-1.0-1.5-1.4-1.5-1.2-1.11.11.1-1.60.9-0.90.9-1.6-0.9-0.9
Pavlov. Cond. lever contacts0.81.22.30.6-1.40.4-0.4-0.8-1.3-1.2-1.4-1.1-1.21.21.2-1.50.8-0.80.8-1.5-0.8-0.8
Pavlov. Cond. magazine entry number1.11.43.1-1.41.80.20.81.11.51.41.51.31.0-1.0-1.01.5-1.01.0-1.01.51.01.0
Pavlov. Cond. intertrial magazine entries0.20.41.4-1.11.00.11.21.0-0.2-0.3-0.3-0.30.5-0.5-0.5-0.30.4-0.40.4-0.4-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.1.41.93.71.1-1.7-0.1-0.5-0.9-1.8-1.7-1.9-1.6-1.11.11.1-1.91.2-1.21.2-1.9-1.2-1.2
Pavlov. Cond. response bias1.62.24.51.0-1.80.1-0.4-1.0-2.0-1.8-2.0-1.7-1.31.31.3-2.11.3-1.31.3-2.1-1.3-1.3
Time in closed arm before self-admin1.11.44.2-2.01.60.02.11.8-0.7-0.8-0.8-0.81.2-1.2-1.2-0.81.0-1.01.0-0.8-1.0-1.0
Time in closed arm after self-admin1.41.54.4-2.11.10.62.01.4-1.1-1.2-1.2-1.20.5-0.5-0.5-1.41.1-1.11.1-1.4-1.1-1.1
Time in open arm before self-admin0.20.30.80.0-0.80.7-0.2-0.6-0.4-0.3-0.4-0.2-0.90.90.9-0.60.1-0.10.1-0.6-0.1-0.1
Time in open arm after self-admin0.30.42.71.6-1.0-0.7-1.2-0.9-0.00.00.10.1-0.30.30.30.2-0.10.1-0.10.20.10.1
Bone: periosteal estimation0.20.42.9-1.70.91.31.20.80.30.20.20.2-0.10.10.1-0.0-0.20.2-0.2-0.10.20.2
Bone: periosteal perimeter0.30.41.1-0.9-0.21.10.60.1-0.6-0.6-0.8-0.6-0.70.70.7-1.00.4-0.40.4-1.1-0.4-0.4
Bone: post-yield work0.10.20.6-0.50.50.00.70.6-0.3-0.3-0.3-0.30.4-0.4-0.4-0.30.4-0.40.4-0.4-0.4-0.4
Progressive ratio test 1 active lever presses0.20.21.7-1.30.31.20.60.20.20.10.00.2-0.50.50.5-0.1-0.20.2-0.2-0.20.20.2
Progressive ratio test 1 breakpoint0.20.21.7-1.30.31.20.60.20.20.10.00.2-0.50.50.5-0.1-0.20.2-0.2-0.20.20.2
Progressive ratio test 1 inactive lever presses0.60.92.7-1.51.6-0.21.61.6-0.2-0.3-0.3-0.41.2-1.2-1.2-0.30.6-0.60.6-0.2-0.6-0.6
Progressive ratio test 2 active lever presses0.60.72.6-1.60.80.41.41.0-0.7-0.8-0.8-0.80.4-0.4-0.4-0.90.8-0.80.8-1.0-0.8-0.8
Progressive ratio test 2 breakpoint0.70.82.4-1.50.80.41.41.0-0.8-0.8-0.9-0.80.4-0.4-0.4-1.00.8-0.80.8-1.0-0.8-0.8
Progressive ratio test 2 inactive lever presses1.11.86.6-2.62.30.12.52.3-0.3-0.4-0.3-0.51.6-1.6-1.6-0.40.8-0.80.8-0.4-0.8-0.8
Incentive Sensitization - Responses0.20.30.4-0.20.3-0.50.50.5-0.6-0.6-0.6-0.60.6-0.6-0.6-0.50.7-0.70.7-0.5-0.7-0.7
Incentive Sensitization - Breakpoint0.30.40.6-0.10.3-0.60.50.5-0.7-0.7-0.7-0.70.6-0.6-0.6-0.60.8-0.80.8-0.6-0.8-0.8
Sum of active levers in priming session hrs 5-61.31.21.90.4-0.70.8-1.2-1.11.11.21.11.2-1.11.11.11.1-1.31.3-1.31.11.41.4
Progressive ratio0.30.51.21.0-0.6-0.2-1.1-0.80.70.80.80.8-0.20.20.20.8-0.80.8-0.80.80.80.8
Food seeking constrained by brief footshock1.01.24.70.91.2-2.20.10.90.40.40.70.22.0-2.0-2.01.00.2-0.20.21.1-0.2-0.2
Seeking ratio, punishment vs. effort0.30.51.4-1.01.2-0.31.21.2-0.2-0.3-0.2-0.30.9-0.9-0.9-0.20.5-0.50.5-0.1-0.5-0.5
Retroperitoneal fat weight1.14.76.81.0-1.91.6-2.6-2.62.02.11.92.2-2.32.32.31.8-2.42.4-2.41.72.52.5
Reaction time number correct1.12.24.7-1.31.9-1.02.12.2-0.9-1.0-0.9-1.11.9-1.9-1.9-0.81.4-1.41.4-0.8-1.4-1.4
Reaction time mean minus median1.02.56.80.0-2.41.8-0.7-1.7-1.3-1.2-1.6-1.0-2.62.62.6-1.90.4-0.40.4-2.0-0.4-0.4
Reaction time mean minus median AUC0.82.14.90.6-1.50.20.0-0.6-2.0-1.9-2.1-1.7-1.01.01.0-2.21.3-1.31.3-2.2-1.4-1.4
Reaction time num false alarms1.21.74.00.2-1.0-0.10.3-0.2-1.8-1.7-1.9-1.6-0.50.50.5-1.91.4-1.41.4-2.0-1.4-1.4
Reaction time num false alarms AUC0.71.12.60.0-0.7-0.00.4-0.1-1.4-1.4-1.5-1.3-0.40.40.4-1.61.2-1.21.2-1.6-1.2-1.2
Reaction time trials correct on left1.12.24.7-1.31.9-1.02.12.2-0.9-1.0-0.9-1.11.9-1.9-1.9-0.81.4-1.41.4-0.8-1.4-1.4
Reaction time trials on left1.12.14.4-1.21.8-0.92.12.1-0.9-1.0-0.9-1.11.8-1.8-1.8-0.81.3-1.31.3-0.8-1.4-1.4
Reaction time mean1.42.38.82.2-3.00.4-2.3-2.5-0.7-0.4-0.7-0.3-2.22.32.3-0.8-0.20.2-0.2-0.80.10.1
Reaction time mean AUC1.32.08.02.2-2.80.2-2.1-2.3-0.9-0.7-0.9-0.5-2.02.02.0-0.90.1-0.10.1-1.0-0.2-0.2
Median of all reaction times1.42.07.32.7-2.7-0.1-2.5-2.5-0.20.0-0.10.1-1.81.81.8-0.1-0.50.5-0.5-0.10.40.4
Reaction time omissions0.60.82.81.0-1.70.5-1.0-1.3-0.6-0.5-0.6-0.3-1.41.41.4-0.70.0-0.00.0-0.7-0.0-0.0
Reaction time false alarm rate0.60.92.40.5-1.60.5-0.6-1.1-0.9-0.9-1.0-0.7-1.31.31.3-1.10.4-0.40.4-1.2-0.4-0.4
Reaction time premature initiation rate0.30.41.10.1-1.00.8-0.3-0.7-0.6-0.6-0.7-0.5-1.01.01.0-0.80.2-0.20.2-0.9-0.2-0.2
Reaction time premature initiations0.30.51.1-0.4-0.10.20.60.3-0.9-0.9-1.0-0.9-0.10.10.1-1.00.8-0.80.8-1.1-0.7-0.7
Std. dev. reaction times1.12.16.61.0-2.61.2-1.4-2.0-1.0-0.8-1.1-0.6-2.42.42.4-1.30.1-0.10.1-1.4-0.1-0.1
Reaction time trials completed1.12.14.4-1.21.8-0.92.12.1-0.9-1.0-0.9-1.11.8-1.8-1.8-0.81.3-1.31.3-0.8-1.4-1.4
Reaction time trials AUC1.22.34.4-1.11.8-1.12.12.1-1.1-1.2-1.1-1.31.9-1.9-1.9-1.01.5-1.51.5-0.9-1.6-1.6
Run reversals in cocaine runway, females0.20.21.11.1-0.3-0.8-0.7-0.30.10.10.20.10.3-0.3-0.30.4-0.10.1-0.10.40.10.1
Run reversals in cocaine runway, males2.82.84.1-0.41.0-1.41.71.6-1.8-1.9-1.7-1.91.4-1.4-1.4-1.62.0-2.02.0-1.5-2.0-2.0
Latency to leave start box in cocaine runway0.50.60.90.4-0.60.6-0.9-0.90.80.80.70.8-0.70.70.70.7-0.90.9-0.90.60.90.9
Latency to leave start box in cocaine runway, F1.41.62.6-0.1-0.10.9-0.9-0.71.61.61.61.6-0.50.50.51.5-1.61.6-1.61.51.61.6
Latency to leave start box in cocaine runway, M0.40.40.70.4-0.4-0.30.0-0.1-0.8-0.8-0.8-0.8-0.10.10.1-0.80.7-0.70.7-0.8-0.7-0.7
Std. dev. time between licks in bursts0.81.12.0-0.60.2-0.11.00.6-1.3-1.3-1.4-1.30.1-0.1-0.1-1.41.2-1.21.2-1.4-1.2-1.2
Total sessions with >9 infusions0.60.71.00.5-0.50.3-1.0-0.80.90.90.90.9-0.50.50.50.9-0.90.9-0.91.00.90.9
Short access day 1 total inactive lever presses0.70.92.3-0.30.80.0-0.10.21.31.31.41.20.4-0.4-0.41.4-1.01.0-1.01.51.01.0
Short access day 10 total inactive lever presses1.43.47.4-1.32.00.40.30.92.52.42.62.21.0-1.0-1.02.6-1.81.8-1.82.71.81.8
Short access day 1 total infusions0.60.71.81.3-0.5-0.4-1.3-0.90.80.91.00.9-0.20.20.21.1-0.80.8-0.81.10.80.8
Short access day 10 total infusions0.10.10.50.7-0.4-0.4-0.6-0.4-0.00.00.00.0-0.10.10.10.1-0.00.0-0.00.10.00.0
Short access total infusions1.11.43.21.4-1.20.3-1.8-1.51.01.11.01.1-1.01.01.01.1-1.21.2-1.21.11.21.2
Short access day 1 locomotion0.50.62.10.6-1.50.6-0.8-1.1-0.5-0.5-0.6-0.4-1.31.31.3-0.70.1-0.10.1-0.8-0.1-0.1
Short access day 10 total locomotion0.10.20.5-0.20.7-0.30.20.50.50.50.60.40.6-0.6-0.60.7-0.30.3-0.30.70.30.3
Short access total locomotion0.50.61.61.0-1.20.3-1.3-1.30.20.30.20.4-1.01.01.00.2-0.50.5-0.50.20.50.5
One hour access (0.3 mA shock)4.75.49.3-1.92.0-1.23.02.7-2.2-2.3-2.2-2.42.2-2.2-2.2-2.12.5-2.52.5-2.2-2.5-2.5
Compulsive drug intake0.70.82.91.4-0.2-1.7-0.20.1-0.9-0.9-0.7-0.90.8-0.8-0.8-0.61.0-1.01.0-0.5-1.0-1.0
One hour access (shock baseline)0.91.44.0-2.00.70.81.81.1-1.1-1.2-1.3-1.20.2-0.2-0.2-1.51.1-1.11.1-1.6-1.1-1.1
Social response proportion1.31.48.5-2.3-0.32.90.6-0.30.20.2-0.20.3-1.81.81.8-0.5-0.60.6-0.6-0.70.60.6
Social responses1.01.33.2-1.80.60.91.71.0-1.1-1.2-1.3-1.20.00.00.0-1.51.1-1.11.1-1.5-1.0-1.0
Social time1.62.13.81.8-1.6-1.0-0.6-0.8-1.9-1.9-1.9-1.8-0.50.50.5-1.81.6-1.61.6-1.8-1.4-1.4
Soleus weight0.30.75.3-2.31.51.01.71.40.20.10.00.10.3-0.3-0.3-0.10.0-0.00.0-0.1-0.1-0.1
Bone: stiffness0.30.51.5-1.0-0.21.00.70.1-0.8-0.8-1.0-0.7-0.60.60.6-1.10.5-0.50.5-1.2-0.5-0.5
Tibialis anterior weight1.55.024.6-5.01.34.71.80.61.91.71.31.8-1.91.91.90.7-2.02.0-2.00.51.91.9
Time to tail flick, vehicle, before self-admin1.92.04.91.2-2.21.1-2.0-2.20.50.60.40.7-2.22.22.20.3-1.11.1-1.10.31.11.1
Time to tail flick, vehicle, after self-admin0.20.30.8-0.1-0.40.10.2-0.1-0.7-0.7-0.8-0.7-0.30.30.3-0.90.6-0.60.6-0.9-0.5-0.5
Time to tail flick, test, before self-admin0.20.21.7-1.30.90.61.00.80.20.20.10.10.3-0.3-0.30.0-0.10.1-0.10.0-0.0-0.0
Time to tail flick, test, after self-admin0.80.81.50.7-1.00.7-1.2-1.20.70.70.70.8-1.11.11.10.6-0.90.9-0.90.60.90.9
Delta time to tail flick, vehicle, before/after SA1.51.41.9-0.20.7-1.01.21.1-1.2-1.2-1.2-1.31.2-1.2-1.2-1.11.4-1.41.4-1.1-1.4-1.4
Delta time to tail flick, test, before/after SA0.30.31.61.3-0.7-0.5-1.1-0.80.20.30.30.3-0.20.20.20.4-0.30.3-0.30.40.30.3
Tibia length1.95.310.8-3.11.33.30.50.12.92.72.62.7-1.31.21.22.2-2.62.6-2.62.22.72.7
Ambulatory time before self-admin0.20.30.70.2-0.80.4-0.3-0.6-0.5-0.5-0.6-0.4-0.80.80.8-0.60.2-0.20.2-0.7-0.2-0.2
Ambulatory time after self-admin0.91.11.90.3-0.2-0.70.50.4-1.4-1.3-1.3-1.30.4-0.4-0.4-1.31.3-1.31.3-1.3-1.2-1.2
Bone: tissue strength0.70.71.9-0.11.4-0.90.51.00.70.60.90.51.4-1.4-1.41.0-0.20.2-0.21.10.20.2
Total heroin consumption1.61.93.91.9-2.0-0.9-1.0-1.2-1.8-1.6-1.7-1.5-0.70.70.7-1.71.2-1.21.2-1.7-1.1-1.1
Bone: trabecular number0.81.35.6-2.41.71.31.31.21.21.21.11.10.3-0.4-0.40.9-0.90.9-0.90.90.80.8
Bone: trabecular spacing0.50.64.82.2-1.0-1.5-1.1-0.7-0.6-0.5-0.4-0.50.2-0.2-0.2-0.20.5-0.50.5-0.1-0.4-0.4
Bone: trabecular thickness0.70.94.5-2.11.31.51.10.81.00.90.90.9-0.0-0.0-0.00.7-0.80.8-0.80.60.80.8
Bone: trabecular tissue density2.02.99.70.1-2.82.3-1.4-2.4-0.5-0.4-0.8-0.1-3.13.13.1-1.1-0.50.5-0.5-1.30.50.5
Water consumed over 24 hours0.70.95.0-2.21.90.51.81.60.40.30.30.20.9-0.8-0.80.2-0.00.0-0.00.20.00.0
Number of responses in last shaping day0.20.20.50.6-0.50.0-0.7-0.60.30.30.30.4-0.30.30.30.4-0.40.4-0.40.40.40.4