Hub : Genes

Mllt6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr10_83162550_83163404 0.03 0.02 8.6e-03 0.02 0.01 0.01 0.01 1.0e-02 1.7e-02 1.2e-02 1.4e-02
2 Brain intron excision ratio chr10_83162634_83163404 0.03 0.02 2.6e-03 0.02 0.02 0.02 0.02 4.4e-03 3.6e-03 2.2e-03 2.6e-03
3 Brain isoform ratio NM_001427040.1 0.02 0.02 5.4e-03 0.01 0.02 0.01 0.01 1.2e-02 8.0e-03 2.3e-02 2.0e-02
4 Adipose mRNA stability Mllt6 0.03 0.02 5.6e-05 0.03 0.03 0.02 0.02 7.4e-04 2.7e-04 1.5e-03 9.3e-04
5 NAcc isoform ratio XM_039087725.2 0.02 0.01 1.1e-03 0.02 0.02 0 0.02 1.2e-03 6.9e-04 1.1e-01 1.5e-03
6 NAcc isoform ratio NM_001427040.1 0.02 0.01 1.7e-03 0.01 0.02 0.01 0.01 2.2e-03 1.2e-03 3.4e-03 2.8e-03
7 Liver gene expression Mllt6 0.09 0.05 1.3e-14 0.11 0.11 0.12 0.12 2.4e-12 3.9e-12 4.8e-13 1.9e-13
8 Brain alternative TSS XM_039087726.2 0.02 0.02 5.0e-03 0.01 0.01 0 0.01 1.2e-02 6.0e-02 2.2e-01 6.9e-02
9 Brain alternative TSS XM_039087726.2 0.02 0.02 5.5e-03 0.02 0.01 0 0.01 1.2e-02 6.5e-02 2.2e-01 7.2e-02
10 Brain isoform ratio XM_039087725.2 0.02 0.02 7.2e-03 0.02 0.02 0.01 0.01 6.1e-03 8.2e-03 1.7e-02 1.5e-02
11 Brain gene expression Mllt6 0.06 0.04 8.2e-06 0.07 0.05 0.06 0.06 5.2e-07 1.2e-05 3.1e-06 3.9e-06
12 pVTA mRNA stability Mllt6 0.08 0.06 9.9e-03 -0 0.01 0.02 0 5.4e-01 4.8e-02 1.8e-02 2.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.62.73.8-1.91.8-1.8-1.81.8-1.8-1.71.51.51.6-1.6-0.6
Area under the delay curve1.31.54.5-1.11.0-1.0-1.01.0-1.0-1.21.21.21.0-1.0-2.1
BMI with tail2.07.030.22.7-2.42.02.1-2.12.12.4-2.3-2.3-1.91.95.5
BMI without tail1.44.35.32.3-2.22.12.1-2.12.12.0-2.0-2.0-2.02.01.6
Body weight6.829.933.45.7-5.85.75.7-5.75.75.6-5.6-5.6-5.45.43.0
Weight adjusted by age0.10.20.30.5-0.50.50.5-0.50.50.4-0.6-0.6-0.50.5-0.3
Bone surface0.00.10.2-0.0-0.10.10.1-0.10.10.1-0.4-0.4-0.30.30.4
Bone volume0.00.10.2-0.40.3-0.3-0.30.3-0.3-0.2-0.0-0.00.1-0.10.4
Breakpoint value in progressive ratio session1.82.22.91.5-1.51.61.6-1.61.61.3-1.7-1.7-1.41.4-0.2
Number of licking bursts0.40.60.7-0.70.9-0.8-0.80.8-0.8-0.70.80.80.9-0.9-0.8
Context. condit. distance diff. score0.30.40.70.9-0.70.60.6-0.60.60.5-0.6-0.6-0.50.50.8
Locomotion velocity, session 11.21.31.91.1-1.11.11.1-1.11.11.3-1.1-1.1-1.21.21.4
Locomotion distance, session 13.84.86.02.4-2.32.42.4-2.42.42.3-2.0-2.0-2.22.20.1
Locomotion velocity, session 20.81.01.20.9-0.91.11.1-1.11.11.1-0.9-0.9-1.01.0-0.5
Locomotion distance, session 21.21.72.21.2-1.31.51.4-1.41.51.3-1.1-1.1-1.21.2-1.2
Locomotion velocity, session 30.20.20.30.4-0.50.50.5-0.50.50.5-0.4-0.4-0.50.5-0.2
Locomotion distance, session 30.70.81.70.8-0.81.00.9-0.91.00.8-0.6-0.6-0.80.8-1.3
Stereotopy head waving bouts, day 33.23.74.8-2.22.1-2.2-2.22.2-2.2-2.01.71.71.8-1.8-0.2
Stereotopy head waving duration, day 30.60.71.0-1.00.9-1.0-1.01.0-1.0-0.80.60.60.8-0.80.6
Locomotion velocity, session 70.50.61.21.1-0.90.90.9-0.90.90.6-0.5-0.5-0.70.7-0.3
Locomotion distance, session 70.30.44.00.4-0.20.40.4-0.30.4-0.10.10.1-0.10.1-2.0
Stereotopy head waving bouts, day 70.80.91.9-1.41.1-1.2-1.21.2-1.2-0.90.70.70.6-0.60.3
Stereotopy head waving duration, day 70.20.20.7-0.80.4-0.6-0.60.5-0.6-0.30.00.00.0-0.00.8
Locomotion velocity, session 86.17.38.93.0-2.92.82.8-2.82.82.7-2.6-2.6-2.62.62.2
Locomotion distance, session 81.72.53.01.7-1.71.71.7-1.71.71.6-1.5-1.5-1.61.60.2
Degree of sensitization distance0.10.10.20.5-0.30.30.3-0.30.30.2-0.3-0.3-0.20.20.3
Degree of sensitization stereotypy1.21.32.4-1.61.3-1.4-1.41.3-1.4-1.20.90.90.8-0.8-0.2
Conditioned locomotion0.20.20.3-0.60.5-0.5-0.50.5-0.5-0.50.50.50.4-0.4-0.3
Cocaine response after cond. corrected1.82.13.4-1.91.7-1.6-1.61.5-1.5-1.41.41.41.4-1.4-0.5
Cocaine response after cond. not corrected2.73.24.9-2.22.0-1.9-1.91.9-1.8-1.81.71.71.6-1.6-1.4
Cocaine response before conditioning0.81.04.1-0.90.8-0.8-0.80.9-0.8-1.10.90.90.6-0.6-2.0
Saline control response0.10.21.3-0.10.2-0.1-0.20.2-0.2-0.30.40.40.3-0.3-1.2
Bone: connectivity density2.23.54.3-2.12.0-2.0-2.02.0-2.0-2.01.71.71.8-1.8-1.1
Bone: cortical apparent density3.95.37.6-2.82.4-2.4-2.42.4-2.4-2.42.22.21.9-1.9-2.3
Bone: cortical area0.20.30.4-0.60.5-0.5-0.50.5-0.5-0.60.60.60.4-0.4-0.6
Bone: cortical porosity1.31.42.2-1.01.2-1.1-1.11.1-1.1-1.01.51.51.4-1.4-0.7
Bone: cortical porosity1.31.52.2-1.01.2-1.1-1.11.1-1.1-1.11.51.51.4-1.4-0.9
Bone: cortical thickness1.32.14.3-1.71.5-1.3-1.31.3-1.3-1.41.41.41.2-1.2-2.1
Bone: cortical thickness5.05.912.5-2.42.4-2.2-2.22.2-2.2-2.42.52.52.2-2.2-3.5
Bone: cortical tissue density3.85.27.6-2.82.4-2.3-2.42.4-2.3-2.42.12.11.9-1.9-2.3
Condit. Reinf. active minus inactive responses0.30.40.5-0.60.6-0.7-0.70.7-0.7-0.70.50.50.6-0.6-0.3
Condit. Reinf. active-inactive response ratio0.80.81.1-0.70.9-1.0-1.01.0-1.0-1.00.90.91.0-1.0-0.1
Condit. Reinf. active responses0.50.60.9-0.90.9-0.9-0.90.9-0.9-0.80.60.60.8-0.8-0.1
Condit. Reinf. inactive responses0.40.50.9-0.90.9-0.8-0.80.8-0.8-0.60.60.60.7-0.7-0.5
Incentive salience index mean1.11.41.6-1.21.3-1.2-1.21.2-1.2-1.21.21.21.2-1.2-0.8
Condit. Reinf. lever presses1.21.71.9-1.31.4-1.3-1.31.3-1.3-1.31.41.41.4-1.4-1.1
Condit. Reinf. active minus inactive responses0.70.91.8-0.80.9-0.8-0.80.8-0.8-0.81.11.11.0-1.0-1.3
Condit. Reinf. active-inactive response ratio0.30.30.5-0.70.6-0.6-0.60.6-0.6-0.50.60.60.6-0.6-0.0
Condit. Reinf. active responses1.21.63.1-1.01.2-1.1-1.11.1-1.1-1.21.41.41.4-1.4-1.7
Condit. Reinf. inactive responses2.12.74.5-1.41.6-1.5-1.51.5-1.5-1.61.71.71.7-1.7-2.1
Condit. Reinf. lever presses0.10.11.0-0.10.2-0.1-0.10.1-0.1-0.10.30.30.3-0.3-1.0
Condit. Reinf. lever reinforcers received1.21.63.7-1.01.2-1.0-1.11.1-1.1-1.11.41.41.4-1.4-1.9
Conditioned reinforcement - actives0.81.41.8-1.01.1-1.1-1.11.1-1.1-1.31.31.31.3-1.3-0.9
Conditioned reinforcement - inactives0.10.20.60.00.2-0.2-0.20.2-0.2-0.40.80.80.5-0.5-0.6
Conditioned locomotion1.82.43.5-1.31.6-1.5-1.51.5-1.5-1.51.71.71.9-1.9-0.3
Patch foraging indifference point 0 sec1.22.32.6-1.51.6-1.5-1.51.5-1.5-1.41.41.41.6-1.6-1.5
Patch foraging indifference point AUC0.20.30.9-0.1-0.20.20.2-0.20.20.5-0.6-0.6-0.70.71.0
Delay disc. indifference point, 0s delay2.12.35.4-1.41.5-1.4-1.41.4-1.4-1.41.51.51.4-1.4-2.3
Delay disc. indifference point, 16s delay0.50.50.8-0.90.7-0.7-0.80.8-0.8-0.80.50.50.6-0.6-0.9
Delay disc. indifference point, 2s delay3.03.37.0-1.71.8-1.6-1.61.6-1.6-1.71.91.91.8-1.8-2.7
Delay disc. indifference point, 24s delay0.10.10.3-0.4-0.1-0.0-0.00.0-0.00.0-0.3-0.3-0.60.60.0
Delay disc. indifference point, 4s delay1.21.29.8-0.70.7-0.5-0.50.5-0.5-0.80.90.90.6-0.6-3.1
Delay disc. indifference point, 8s delay0.91.01.5-0.90.8-0.9-0.90.9-0.9-1.21.21.21.0-1.0-1.2
Indifference point function ln k0.10.10.60.00.1-0.1-0.10.1-0.1-0.30.40.40.3-0.3-0.8
Indifference point function log k0.10.10.60.00.1-0.1-0.10.1-0.1-0.30.40.40.3-0.3-0.8
Patch foraging total patch changes 0 sec0.71.31.5-1.21.2-1.1-1.11.1-1.1-1.11.11.11.2-1.2-1.2
Patch foraging total patch changes 12 sec3.74.86.3-2.52.4-2.3-2.32.2-2.2-2.12.12.12.2-2.2-1.5
Patch foraging total patch changes 18 sec0.20.20.7-0.80.6-0.6-0.50.5-0.5-0.10.10.10.4-0.40.7
Patch foraging total patch changes 24 sec0.81.42.6-1.61.4-1.4-1.31.3-1.3-1.01.01.01.0-1.0-0.3
Patch foraging total patch changes 6 sec0.71.01.8-1.31.2-1.2-1.11.1-1.1-0.80.80.80.9-0.9-0.2
Patch foraging time to switch 0 sec0.00.10.2-0.10.3-0.2-0.20.2-0.2-0.20.40.40.5-0.5-0.0
Patch foraging water rate 0 sec0.00.00.1-0.1-0.1-0.0-0.00.0-0.0-0.1-0.2-0.2-0.30.30.2
Patch foraging water rate 12 sec0.30.50.70.8-0.80.80.8-0.80.80.7-0.7-0.7-0.80.8-0.5
Patch foraging water rate 18 sec0.81.25.8-0.60.8-0.7-0.80.8-0.8-1.11.11.10.9-0.9-2.4
Patch foraging water rate 24 sec0.30.40.5-0.70.5-0.6-0.60.7-0.6-0.60.60.60.6-0.6-0.6
Patch foraging water rate 6 sec0.71.01.4-1.21.0-1.1-1.11.1-1.1-1.10.90.90.8-0.8-0.7
Seeking ratio, delayed vs. immediate footshock0.40.41.70.7-0.50.40.4-0.40.40.6-0.7-0.7-0.60.61.3
Distance traveled before self-admin0.10.10.70.9-0.40.40.4-0.40.40.1-0.1-0.1-0.00.0-0.3
Distance traveled after self-admin0.70.81.31.1-1.00.90.9-0.90.90.6-1.0-1.0-0.80.81.1
Extensor digitorum longus weight7.931.134.15.7-5.85.75.7-5.75.75.8-5.7-5.7-5.65.63.8
Bone: elastic displacement0.00.00.1-0.20.2-0.2-0.20.2-0.2-0.00.20.20.3-0.30.0
Bone: elastic work0.00.00.3-0.10.00.10.1-0.10.10.10.00.0-0.00.0-0.5
Bone: endosteal estimation1.53.34.32.1-1.91.91.9-1.91.91.8-1.8-1.8-1.61.61.6
Bone: endosteal perimeter1.63.35.02.1-1.91.81.8-1.81.81.8-1.7-1.7-1.51.52.2
Epididymis fat weight0.00.10.30.3-0.40.40.3-0.30.30.3-0.5-0.5-0.40.40.0
Delta time in closed arm before/after self-admin4.23.94.82.2-2.12.02.0-2.02.01.9-2.1-2.1-1.91.91.4
Delta time in open arm before/after self-admin0.10.10.3-0.20.2-0.0-0.10.1-0.1-0.00.30.30.3-0.3-0.5
Diff in mean of infusions in LGA sessions0.00.10.30.6-0.30.30.2-0.20.20.1-0.1-0.1-0.00.00.1
Delay discount exponential model param0.91.04.10.9-0.70.70.8-0.80.81.0-1.0-1.0-0.80.82.0
Extinction: sum of active levers before priming0.80.91.60.9-1.10.80.8-0.70.80.6-1.1-1.1-1.21.20.1
Active lever presses in extinction session 60.10.10.40.0-0.3-0.1-0.00.1-0.1-0.1-0.5-0.5-0.50.50.6
Bone: final force1.21.82.2-1.51.4-1.4-1.41.4-1.4-1.41.31.31.3-1.3-1.3
Bone: final moment1.11.72.2-1.41.4-1.2-1.31.2-1.2-1.31.31.31.3-1.3-1.5
Food consumed during 24 hour testing period0.91.31.61.0-1.11.21.2-1.21.21.3-1.2-1.2-1.31.30.3
Glucose0.40.61.6-1.00.8-0.7-0.70.7-0.7-0.70.60.60.5-0.5-1.2
Heart weight3.24.96.32.5-2.42.12.2-2.22.22.2-2.1-2.1-2.12.12.3
Delay discount hyperbolic model param0.91.04.50.8-0.70.70.7-0.70.70.9-1.0-1.0-0.80.82.1
Intermittent access intake day 1-15 change0.10.21.20.5-0.50.30.3-0.30.30.1-0.2-0.2-0.40.41.1
Intermittent access intake escalation0.10.21.30.4-0.40.20.2-0.20.20.1-0.2-0.2-0.30.31.1
Intermittent access intake escalation 21.01.14.70.9-1.00.70.7-0.70.70.8-1.0-1.0-1.11.12.2
Intermitt. access day 1 inactive lever presses0.20.71.3-0.50.6-0.7-0.70.7-0.7-0.91.11.10.9-0.9-1.1
Intermitt. access day 15 inactive lever presses0.30.71.0-0.70.8-1.0-0.90.9-0.9-0.80.90.90.8-0.80.5
Intermitt. access escalation Index0.81.11.80.9-1.01.21.2-1.21.21.4-1.2-1.2-0.80.80.4
Intermittent access day 1 total infusions0.00.00.1-0.10.0-0.0-0.10.1-0.1-0.20.10.10.1-0.1-0.3
Intermittent access day 15 total infusions0.10.10.30.4-0.40.30.3-0.20.20.0-0.2-0.2-0.30.30.6
Intermittent access terminal intake (last 3 days)0.10.10.6-0.10.0-0.2-0.20.2-0.2-0.2-0.0-0.00.0-0.00.8
Intermittent access total infusions0.10.10.10.2-0.30.30.2-0.20.20.1-0.3-0.3-0.30.30.2
Intermittent access day 1 locomotion0.30.31.0-0.30.5-0.4-0.40.4-0.4-0.50.70.70.7-0.7-1.0
Intermittent access day 15 total locomotion0.40.71.3-0.60.7-0.9-0.90.9-0.9-1.11.11.10.7-0.7-0.1
Intermittent access total locomotion1.31.52.2-1.01.2-1.2-1.21.2-1.2-1.41.51.51.3-1.3-0.7
Intermittent access standard deviation0.10.10.6-0.20.2-0.3-0.30.4-0.4-0.40.20.20.1-0.10.8
Left kidney weight1.35.97.02.4-2.62.62.5-2.52.52.5-2.6-2.6-2.62.6-0.0
Right kidney weight0.20.81.10.7-0.90.90.9-0.90.91.0-1.0-1.0-1.01.0-0.4
Cocaine induced anxiety3.44.85.62.4-2.42.12.2-2.12.12.1-2.1-2.1-2.22.22.2
Post-drug Anxiety0.80.81.81.1-1.00.90.9-0.90.90.8-0.7-0.7-0.80.81.3
Baseline Anxiety3.64.14.8-2.12.1-2.0-2.02.0-2.0-1.92.22.22.0-2.0-1.6
Tail length2.59.717.32.6-3.03.33.2-3.13.22.5-2.8-2.8-3.33.3-4.2
Length with tail5.021.626.14.5-4.95.15.0-5.05.04.6-4.6-4.6-4.94.9-1.7
Length without tail3.210.212.23.3-3.33.43.4-3.33.43.5-3.2-3.2-3.23.21.4
Times rat made contact with spout0.70.81.1-1.01.0-0.9-0.90.9-0.9-0.70.90.90.8-0.8-0.9
Lifetime Intake0.00.00.00.1-0.20.10.1-0.10.1-0.0-0.2-0.2-0.10.10.0
Liver weight, left0.20.40.80.5-0.70.50.5-0.50.50.5-0.8-0.8-0.90.90.4
Liver weight, right0.20.31.9-0.70.4-0.5-0.50.5-0.5-0.60.30.3-0.10.1-1.4
Locomotor activity0.40.71.0-0.90.9-1.0-1.01.0-1.0-0.90.50.50.8-0.80.3
Locomotor testing distance2.54.65.7-2.12.2-2.4-2.42.4-2.4-2.42.02.02.2-2.2-0.2
Locomotor testing rearing2.95.97.4-2.72.5-2.7-2.72.7-2.7-2.72.12.12.2-2.2-1.3
Locomotion in novel chamber2.12.74.3-1.71.7-1.8-1.71.7-1.7-1.51.51.51.3-1.3-2.1
Locomotion in novel chamber post-restriction0.20.40.6-0.60.7-0.6-0.50.5-0.5-0.20.50.50.8-0.80.7
Fecal boli incidents, locomotor time 10.40.63.70.7-0.60.40.4-0.40.40.6-0.7-0.7-0.60.61.9
Change in fecal boli incidents, locomotor task0.50.52.0-0.70.6-0.6-0.60.6-0.6-0.70.70.70.5-0.5-1.4
Time >=10cm from walls, locomotor time 10.91.01.8-1.01.0-0.9-0.90.9-0.9-0.91.31.30.9-0.9-0.7
Bouts of movement, locomotor time 10.20.20.40.6-0.50.60.6-0.60.60.5-0.4-0.4-0.20.2-0.2
Total resting periods, locomotor time 10.30.30.60.7-0.60.80.7-0.70.70.6-0.5-0.5-0.30.3-0.3
Rest time, locomotor task time 10.10.10.60.00.10.10.1-0.20.20.30.20.20.4-0.4-0.8
Distance moved, locomotor task time 10.10.10.4-0.30.2-0.3-0.30.3-0.3-0.60.10.10.0-0.0-0.6
Vertical activity count, locomotor time 10.10.10.30.5-0.50.20.2-0.20.2-0.1-0.3-0.3-0.50.50.5
Time >=10cm from walls, locomotor time 21.42.03.4-1.31.3-1.3-1.31.3-1.3-1.41.61.61.3-1.3-1.9
Bouts of movement, locomotor time 20.10.20.4-0.20.3-0.4-0.40.4-0.4-0.60.40.40.6-0.6-0.2
Total resting periods, locomotor time 20.00.10.20.10.1-0.2-0.20.2-0.2-0.40.30.30.5-0.5-0.0
Rest time, locomotor task time 20.81.01.91.4-1.01.11.1-1.11.11.1-0.9-0.9-0.70.70.5
Distance moved, locomotor task time 20.10.10.9-0.1-0.10.10.1-0.10.1-0.0-0.3-0.3-0.30.3-1.0
Vertical activity count, locomotor time 20.10.10.70.2-0.30.20.2-0.20.2-0.1-0.0-0.0-0.20.2-0.8
Light reinforcement 11.33.14.1-1.71.8-1.7-1.71.7-1.7-1.71.91.92.0-2.0-0.8
Light reinforcement 20.50.81.1-1.00.9-0.9-0.90.9-0.9-0.81.01.00.9-0.9-0.7
Bone: marrow area1.43.14.12.0-1.91.91.8-1.81.81.8-1.7-1.7-1.61.61.5
Bone: maximum diameter0.00.10.5-0.10.1-0.1-0.10.1-0.1-0.10.10.10.2-0.20.7
Bone: maximum force0.00.00.1-0.20.2-0.1-0.20.2-0.2-0.20.20.20.1-0.1-0.4
Bone: maximum moment0.00.00.3-0.10.2-0.0-0.10.1-0.1-0.20.30.30.1-0.1-0.5
Mean time between licks in bursts0.82.02.61.6-1.51.51.5-1.51.51.6-1.3-1.3-1.21.21.2
Mean num. licks in bursts0.00.00.1-0.1-0.10.10.0-0.00.0-0.00.00.0-0.10.1-0.3
Cd content in liver0.80.91.61.3-1.11.00.9-1.00.90.7-0.8-0.8-0.80.81.1
Co content in liver2.22.52.91.6-1.71.61.6-1.61.61.5-1.7-1.7-1.61.61.0
Cu content in liver0.60.81.20.9-0.81.01.0-1.01.01.1-0.8-0.8-0.70.70.4
Fe content in liver2.02.52.91.6-1.61.71.7-1.71.71.7-1.6-1.6-1.51.50.5
K content in liver0.00.00.2-0.20.10.00.0-0.00.00.10.20.20.0-0.0-0.4
Mg content in liver0.20.21.9-0.30.2-0.1-0.10.1-0.0-0.00.20.2-0.00.0-1.4
Mn content in liver0.10.10.5-0.20.2-0.1-0.10.1-0.1-0.10.30.30.3-0.3-0.7
Na content in liver0.20.20.3-0.50.5-0.5-0.40.4-0.4-0.20.50.50.5-0.50.3
Rb content in liver1.41.61.9-1.11.3-1.3-1.31.3-1.3-1.31.31.31.4-1.4-1.1
Se content in liver2.83.34.5-2.12.0-2.0-1.91.9-1.9-1.81.81.81.8-1.8-0.8
Sr content in liver1.21.11.31.0-1.11.11.1-1.11.11.0-1.0-1.0-1.11.1-0.6
Zn content in liver1.71.92.2-1.21.4-1.3-1.31.3-1.3-1.31.51.51.5-1.5-1.3
Bone: minimum diameter0.40.81.01.0-1.01.00.9-0.90.90.8-0.9-0.9-1.01.00.5
Time in familiar zone, hab. session 10.40.40.6-0.50.5-0.7-0.70.7-0.7-0.80.60.60.5-0.50.3
Time in novel zone, hab. session 10.80.81.1-0.91.0-0.9-0.90.9-0.9-0.70.90.91.0-1.0-0.4
Total zone transitions, hab. session 12.33.24.01.8-1.92.02.0-2.02.01.8-1.7-1.7-1.81.8-0.5
Total locomotion distance, hab. session 10.10.21.60.2-0.10.30.2-0.20.20.10.00.00.0-0.0-1.3
Locomotion velocity, hab. session 10.60.81.51.0-0.91.01.0-1.01.00.8-0.7-0.7-0.70.7-1.2
Time in familiar zone, hab. session 20.70.81.0-0.60.8-0.9-0.90.9-0.9-1.00.90.91.0-1.00.4
Time in novel zone, hab. session 20.10.11.0-0.20.1-0.0-0.00.0-0.0-0.00.10.10.0-0.0-1.0
Total zone transitions, hab. session 20.50.70.91.0-0.91.00.9-0.90.90.8-0.7-0.7-0.80.8-0.1
Total locomotion distance, hab. session 20.00.10.20.4-0.30.30.3-0.30.30.2-0.1-0.1-0.10.10.0
Locomotion velocity, hab. session 20.20.20.40.7-0.60.60.5-0.50.50.4-0.4-0.4-0.40.4-0.0
Novel to familiar place preference ratio1.71.92.51.1-1.41.41.4-1.41.41.4-1.6-1.6-1.61.6-0.1
Novelty place preference1.11.21.60.8-1.11.11.1-1.11.11.0-1.3-1.3-1.31.3-0.4
Time in novel zone, NPP test0.40.40.60.4-0.60.60.6-0.60.60.5-0.7-0.7-0.80.8-0.7
Total zone transitions, NPP test0.40.61.70.7-0.70.90.8-0.80.80.7-0.4-0.4-0.60.6-1.3
Total locomotion distance, NPP test0.10.11.3-0.00.10.10.1-0.10.10.00.30.30.2-0.2-1.1
Locomotion velocity, NPP test0.30.40.80.6-0.60.80.7-0.70.70.7-0.4-0.4-0.40.4-0.9
Intraocular pressure1.52.22.91.6-1.71.41.4-1.41.41.1-1.6-1.6-1.71.70.6
Delta distance traveled before/after self-admin0.70.72.00.8-0.80.70.7-0.70.70.7-0.9-0.9-0.90.91.4
Delta ambulatory time before/after self-admin0.20.20.80.2-0.40.40.4-0.40.40.4-0.6-0.6-0.50.50.9
Parametrial fat weight0.51.32.2-1.01.0-1.0-1.11.1-1.1-1.21.11.11.1-1.1-1.5
Pavlov. Cond. lever latency2.43.13.31.8-1.81.81.8-1.81.81.8-1.7-1.7-1.71.71.5
Pavlov. Cond. magazine entry latency8.711.213.0-3.63.5-3.5-3.53.5-3.5-3.43.43.43.2-3.2-2.0
Pavlov. Cond. change in total contacts7.17.510.6-3.32.9-3.0-3.03.0-3.0-2.82.52.52.4-2.4-2.0
Pavlov. Cond. index score8.310.412.0-3.53.4-3.4-3.43.4-3.4-3.43.23.23.1-3.1-2.2
Pavlov. Cond. latency score6.48.09.4-3.13.0-3.0-3.03.0-3.0-2.92.82.82.7-2.7-2.1
Pavlov. Cond. lever contacts3.23.84.0-2.02.0-2.0-2.02.0-2.0-2.02.02.02.0-2.0-1.6
Pavlov. Cond. magazine entry number12.215.418.94.3-4.24.24.2-4.24.24.1-3.9-3.9-3.73.72.2
Pavlov. Cond. intertrial magazine entries1.41.72.11.3-1.31.41.4-1.41.41.4-1.3-1.3-1.21.20.3
Pavlov. Cond. lever-magazine prob. diff.9.711.913.9-3.73.6-3.6-3.63.6-3.6-3.63.43.43.3-3.3-2.3
Pavlov. Cond. response bias9.511.813.8-3.73.6-3.6-3.63.6-3.6-3.63.43.43.3-3.3-2.1
Pavlov. Cond. lever latency0.20.30.30.5-0.60.60.5-0.50.60.5-0.5-0.5-0.60.60.2
Pavlov. Cond. magazine entry latency0.10.10.80.2-0.20.30.3-0.30.30.3-0.1-0.1-0.20.2-0.9
Pavlov. Cond. change in total contacts0.40.60.9-0.60.8-0.7-0.70.7-0.7-0.70.90.90.9-0.9-0.4
Pavlov. Cond. index score0.10.10.3-0.40.4-0.4-0.30.3-0.3-0.30.40.40.4-0.4-0.5
Pavlov. Cond. latency score0.10.10.5-0.30.3-0.3-0.30.3-0.3-0.20.40.40.3-0.3-0.7
Pavlov. Cond. lever contacts0.40.60.7-0.70.8-0.8-0.80.8-0.8-0.70.80.80.8-0.8-0.3
Pavlov. Cond. magazine entry number0.20.31.30.4-0.50.30.4-0.40.30.4-0.6-0.6-0.50.51.1
Pavlov. Cond. intertrial magazine entries1.32.02.31.4-1.51.51.5-1.51.51.5-1.4-1.4-1.41.40.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.20.3-0.2-0.20.2-0.2-0.10.30.30.3-0.3-0.5
Pavlov. Cond. response bias0.70.91.1-1.01.1-1.0-1.01.0-1.0-0.91.01.01.0-1.0-0.5
Time in closed arm before self-admin2.12.63.4-1.71.8-1.6-1.61.6-1.6-1.41.71.71.9-1.9-0.6
Time in closed arm after self-admin0.30.30.60.7-0.60.60.6-0.60.60.7-0.5-0.5-0.50.50.8
Time in open arm before self-admin2.93.24.12.0-1.91.71.8-1.81.81.7-1.9-1.9-1.71.71.4
Time in open arm after self-admin0.40.50.60.7-0.70.70.7-0.70.70.7-0.7-0.7-0.60.60.1
Bone: periosteal estimation0.10.20.30.6-0.50.50.5-0.50.50.4-0.4-0.4-0.40.40.6
Bone: periosteal perimeter0.50.91.71.1-1.01.01.0-1.01.00.9-0.9-0.9-0.80.81.3
Bone: post-yield work0.50.71.31.1-0.90.90.9-0.90.90.8-0.6-0.6-0.70.70.4
Progressive ratio test 1 active lever presses0.50.72.2-0.90.8-0.6-0.70.7-0.7-0.80.60.60.7-0.7-1.5
Progressive ratio test 1 breakpoint0.50.61.9-0.90.8-0.6-0.70.7-0.7-0.80.60.60.7-0.7-1.4
Progressive ratio test 1 inactive lever presses0.10.20.4-0.10.2-0.2-0.20.2-0.2-0.40.60.60.5-0.5-0.7
Progressive ratio test 2 active lever presses0.30.40.6-0.70.6-0.7-0.70.7-0.7-0.80.60.60.4-0.4-0.5
Progressive ratio test 2 breakpoint0.40.50.7-0.70.7-0.7-0.70.7-0.7-0.80.70.70.5-0.5-0.7
Progressive ratio test 2 inactive lever presses0.20.30.50.6-0.60.40.5-0.40.40.3-0.5-0.5-0.70.70.4
Incentive Sensitization - Responses0.30.40.6-0.60.7-0.8-0.80.8-0.8-0.70.70.70.5-0.5-0.3
Incentive Sensitization - Breakpoint0.20.30.4-0.50.6-0.7-0.60.6-0.6-0.60.60.60.3-0.3-0.1
Sum of active levers in priming session hrs 5-60.10.10.4-0.3-0.0-0.2-0.30.3-0.3-0.4-0.1-0.1-0.40.4-0.6
Progressive ratio0.00.00.20.20.00.20.1-0.10.20.10.20.20.2-0.2-0.4
Food seeking constrained by brief footshock0.50.71.2-1.10.8-0.8-0.80.8-0.8-0.81.01.00.7-0.7-0.1
Seeking ratio, punishment vs. effort0.10.20.6-0.80.3-0.5-0.50.5-0.5-0.60.20.2-0.00.00.2
Retroperitoneal fat weight0.20.91.7-0.60.9-0.8-0.80.8-0.8-1.01.01.01.1-1.1-1.3
Reaction time number correct0.40.81.21.1-0.91.01.0-1.01.01.1-0.7-0.7-0.70.70.1
Reaction time mean minus median0.00.00.10.2-0.10.20.2-0.20.20.2-0.0-0.00.0-0.00.2
Reaction time mean minus median AUC0.20.60.9-0.60.8-0.7-0.70.7-0.7-0.60.80.80.9-0.9-0.3
Reaction time num false alarms0.50.71.0-0.90.9-0.9-0.90.9-0.9-1.00.80.80.8-0.8-0.7
Reaction time num false alarms AUC0.30.50.7-0.80.8-0.7-0.70.7-0.7-0.90.60.60.7-0.7-0.8
Reaction time trials correct on left0.40.81.21.1-0.91.01.0-1.01.01.1-0.7-0.7-0.70.70.1
Reaction time trials on left0.40.71.11.0-0.91.01.0-1.01.01.1-0.7-0.7-0.60.60.1
Reaction time mean0.10.10.9-0.10.1-0.2-0.10.1-0.10.00.10.10.2-0.20.9
Reaction time mean AUC0.10.11.00.10.0-0.1-0.10.1-0.10.10.00.00.1-0.11.0
Median of all reaction times0.20.31.0-0.40.5-0.6-0.50.5-0.5-0.30.30.30.4-0.41.0
Reaction time omissions0.40.50.8-0.80.8-0.6-0.70.7-0.7-0.70.70.70.7-0.7-0.9
Reaction time false alarm rate1.01.31.9-1.31.2-1.2-1.21.2-1.2-1.41.01.01.0-1.0-0.8
Reaction time premature initiation rate0.60.83.5-0.70.8-0.5-0.60.6-0.6-0.50.90.90.9-0.9-1.9
Reaction time premature initiations0.10.22.10.2-0.00.30.3-0.30.30.30.20.20.2-0.2-1.5
Std. dev. reaction times0.00.00.1-0.20.2-0.2-0.20.2-0.2-0.10.20.20.3-0.30.0
Reaction time trials completed0.40.71.11.0-0.91.01.0-1.01.01.1-0.7-0.7-0.60.60.1
Reaction time trials AUC0.30.61.00.9-0.80.90.9-0.90.91.0-0.6-0.6-0.50.50.1
Run reversals in cocaine runway, females1.41.41.91.4-1.31.21.2-1.21.20.9-1.1-1.1-1.31.30.4
Run reversals in cocaine runway, males0.40.41.70.00.4-0.7-0.60.6-0.6-0.50.70.70.6-0.61.3
Latency to leave start box in cocaine runway2.62.94.91.9-1.61.61.7-1.71.71.7-1.7-1.7-1.41.42.2
Latency to leave start box in cocaine runway, F2.83.24.12.0-1.71.81.9-1.91.92.0-1.8-1.8-1.31.32.0
Latency to leave start box in cocaine runway, M0.60.51.40.7-0.70.50.5-0.50.50.5-0.8-0.8-0.80.81.2
Std. dev. time between licks in bursts0.40.52.30.6-0.60.50.5-0.60.50.7-0.6-0.6-0.60.61.5
Total sessions with >9 infusions0.00.00.2-0.20.1-0.1-0.10.1-0.1-0.20.30.30.2-0.2-0.4
Short access day 1 total inactive lever presses1.11.43.9-1.01.0-0.9-1.01.0-1.0-1.21.21.21.1-1.1-2.0
Short access day 10 total inactive lever presses0.20.62.71.0-0.60.60.7-0.70.70.7-0.6-0.6-0.20.21.6
Short access day 1 total infusions0.00.00.0-0.10.1-0.1-0.10.2-0.2-0.20.10.10.1-0.1-0.0
Short access day 10 total infusions0.10.10.3-0.60.3-0.5-0.50.5-0.5-0.50.20.20.1-0.10.3
Short access total infusions0.00.00.0-0.0-0.10.10.0-0.00.00.0-0.2-0.2-0.10.10.1
Short access day 1 locomotion0.60.81.3-0.90.9-0.9-0.90.9-0.9-0.81.11.10.9-0.9-0.3
Short access day 10 total locomotion1.93.54.5-1.81.9-2.0-1.92.0-2.0-1.92.12.11.9-1.9-0.6
Short access total locomotion0.40.50.8-0.60.6-0.6-0.60.6-0.6-0.60.90.90.8-0.8-0.2
One hour access (0.3 mA shock)0.00.00.1-0.10.1-0.0-0.00.1-0.0-0.3-0.1-0.10.2-0.2-0.4
Compulsive drug intake0.50.64.6-0.70.6-0.2-0.30.3-0.3-0.40.40.40.6-0.6-2.1
One hour access (shock baseline)0.20.31.90.5-0.50.20.2-0.20.20.1-0.4-0.4-0.30.31.4
Social response proportion0.30.43.2-0.00.20.10.0-0.00.0-0.20.60.60.4-0.4-1.8
Social responses0.20.20.5-0.30.4-0.3-0.30.3-0.3-0.40.70.70.5-0.5-0.7
Social time0.10.11.3-0.0-0.1-0.0-0.00.0-0.00.1-0.0-0.0-0.10.11.2
Soleus weight0.41.22.0-1.41.2-1.2-1.21.2-1.2-1.10.90.91.0-1.0-0.7
Bone: stiffness0.10.10.4-0.20.3-0.1-0.20.2-0.2-0.30.40.40.3-0.3-0.6
Tibialis anterior weight1.34.55.22.1-2.22.22.2-2.22.22.3-2.2-2.2-2.32.30.6
Time to tail flick, vehicle, before self-admin0.30.31.1-0.60.3-0.5-0.50.5-0.5-0.80.40.40.2-0.2-1.1
Time to tail flick, vehicle, after self-admin0.10.10.6-0.30.1-0.3-0.20.2-0.2-0.20.10.10.0-0.00.7
Time to tail flick, test, before self-admin0.40.41.40.5-0.60.50.5-0.50.50.6-0.6-0.6-0.70.71.2
Time to tail flick, test, after self-admin0.10.10.2-0.40.1-0.3-0.30.3-0.3-0.2-0.1-0.1-0.10.10.2
Delta time to tail flick, vehicle, before/after SA0.40.40.6-0.70.7-0.7-0.70.7-0.7-0.40.60.60.6-0.60.8
Delta time to tail flick, test, before/after SA1.71.84.1-1.31.3-1.3-1.31.3-1.3-1.31.21.21.2-1.2-2.0
Tibia length0.72.02.61.3-1.41.51.5-1.51.51.5-1.6-1.6-1.51.50.4
Ambulatory time before self-admin0.30.51.51.2-0.80.80.8-0.80.80.6-0.5-0.5-0.40.40.2
Ambulatory time after self-admin2.12.52.91.7-1.71.61.5-1.51.51.3-1.7-1.7-1.61.61.5
Bone: tissue strength0.50.50.80.4-0.60.60.6-0.70.60.8-0.8-0.8-0.80.80.9
Total heroin consumption0.20.20.4-0.60.5-0.6-0.60.6-0.6-0.6-0.0-0.00.2-0.2-0.2
Bone: trabecular number4.77.79.1-3.03.0-2.9-2.92.9-2.9-2.92.72.72.8-2.8-1.5
Bone: trabecular spacing0.81.01.41.2-1.11.01.0-1.01.01.0-0.8-0.8-0.90.91.1
Bone: trabecular thickness0.00.00.0-0.20.1-0.1-0.10.1-0.10.0-0.2-0.2-0.10.10.1
Bone: trabecular tissue density0.00.00.10.0-0.10.10.1-0.10.10.1-0.1-0.1-0.20.2-0.2
Water consumed over 24 hours0.00.00.0-0.00.00.10.1-0.10.10.20.00.0-0.00.0-0.1
Number of responses in last shaping day0.30.31.40.2-0.40.30.3-0.30.30.4-0.5-0.5-0.60.61.2