Hub : Genes

Mllt6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr10_83162550_83163404 0.03 0.02 8.6e-03 0.02 0.01 0.01 0.01 1.0e-02 1.7e-02 1.2e-02 1.5e-02
2 Brain intron excision ratio chr10_83162634_83163404 0.03 0.02 2.6e-03 0.02 0.02 0.02 0.02 4.4e-03 3.6e-03 2.3e-03 2.5e-03
3 Brain isoform ratio NM_001427040.1 0.02 0.02 5.4e-03 0.01 0.02 0.01 0.01 1.2e-02 8.0e-03 2.3e-02 2.1e-02
4 Adipose mRNA stability Mllt6 0.03 0.02 5.6e-05 0.03 0.03 0.02 0.03 7.4e-04 2.7e-04 1.5e-03 8.6e-04
5 NAcc isoform ratio XM_039087725.2 0.02 0.01 1.1e-03 0.02 0.02 0 0.02 1.2e-03 6.9e-04 1.1e-01 1.5e-03
6 NAcc isoform ratio NM_001427040.1 0.02 0.01 1.7e-03 0.01 0.02 0.01 0.01 2.2e-03 1.2e-03 3.4e-03 2.6e-03
7 Liver gene expression Mllt6 0.09 0.05 1.3e-14 0.11 0.11 0.12 0.12 2.4e-12 3.9e-12 4.9e-13 2.1e-13
8 Brain alternative TSS NM_001427040.1 0.02 0.02 9.9e-03 0.01 0 0 0 3.0e-02 1.5e-01 3.2e-01 1.8e-01
9 Brain alternative TSS XM_039087726.2 0.02 0.02 5.0e-03 0.01 0.01 0 0.01 1.2e-02 6.0e-02 2.2e-01 6.3e-02
10 Brain alternative TSS XM_039087726.2 0.02 0.02 5.5e-03 0.02 0.01 0 0.01 1.2e-02 6.5e-02 2.2e-01 7.1e-02
11 Brain isoform ratio XM_039087725.2 0.02 0.02 7.2e-03 0.02 0.02 0.01 0.01 6.1e-03 8.2e-03 1.7e-02 1.3e-02
12 Brain gene expression Mllt6 0.06 0.04 8.2e-06 0.07 0.05 0.06 0.06 5.2e-07 1.2e-05 3.1e-06 3.8e-06
13 pVTA mRNA stability Mllt6 0.08 0.06 9.9e-03 -0 0.01 0.02 0 5.4e-01 4.8e-02 1.9e-02 2.8e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.42.73.81.9-1.8-1.8-1.81.8-1.8-1.71.5-1.5-1.5-1.61.60.6
Area under the delay curve1.01.54.51.1-1.0-1.0-1.01.0-1.0-1.21.2-1.2-1.2-1.01.02.1
BMI with tail2.06.930.2-2.72.42.02.1-2.12.12.4-2.32.32.31.9-1.9-5.5
BMI without tail0.84.35.3-2.32.22.12.1-2.12.12.0-2.02.02.02.0-2.0-1.6
Body weight6.930.033.4-5.75.85.75.7-5.75.75.6-5.65.65.65.4-5.4-3.0
Weight adjusted by age0.10.20.3-0.50.50.50.5-0.50.50.4-0.60.60.60.5-0.50.3
Bone surface0.00.10.20.00.10.10.1-0.10.10.1-0.40.40.40.3-0.3-0.4
Bone volume0.00.10.20.4-0.3-0.3-0.30.3-0.3-0.2-0.00.00.0-0.10.1-0.4
Breakpoint value in progressive ratio session1.22.22.9-1.51.51.61.6-1.61.61.3-1.71.71.71.4-1.40.2
Number of licking bursts0.20.70.70.7-0.9-0.8-0.80.8-0.8-0.70.8-0.8-0.8-0.90.90.8
Context. condit. distance diff. score0.30.40.7-0.90.70.60.6-0.60.60.5-0.60.60.60.5-0.5-0.8
Locomotion velocity, session 11.21.31.9-1.11.11.11.1-1.11.11.3-1.11.11.11.2-1.2-1.4
Locomotion distance, session 13.74.76.0-2.42.32.42.4-2.42.42.3-2.02.02.02.2-2.2-0.1
Locomotion velocity, session 20.80.91.2-0.90.91.11.1-1.11.11.1-0.90.90.91.0-1.00.5
Locomotion distance, session 21.21.62.2-1.21.31.51.4-1.41.51.3-1.11.11.11.2-1.21.2
Locomotion velocity, session 30.20.20.3-0.40.50.50.5-0.50.50.5-0.40.40.40.5-0.50.2
Locomotion distance, session 30.60.71.7-0.80.81.00.9-0.91.00.8-0.60.60.60.8-0.81.3
Stereotopy head waving bouts, day 33.13.74.82.2-2.1-2.2-2.22.2-2.2-2.01.7-1.7-1.7-1.81.80.2
Stereotopy head waving duration, day 30.60.71.01.0-0.9-1.0-1.01.0-1.0-0.80.6-0.6-0.6-0.80.8-0.6
Locomotion velocity, session 70.50.61.2-1.10.90.90.9-0.90.90.6-0.50.50.50.7-0.70.3
Locomotion distance, session 70.30.44.0-0.40.20.40.4-0.30.4-0.10.1-0.1-0.10.1-0.12.0
Stereotopy head waving bouts, day 70.80.91.91.4-1.1-1.2-1.21.2-1.2-0.90.7-0.7-0.7-0.60.6-0.3
Stereotopy head waving duration, day 70.20.20.70.8-0.4-0.6-0.60.5-0.6-0.30.0-0.0-0.0-0.00.0-0.8
Locomotion velocity, session 86.07.38.9-3.02.92.82.8-2.82.82.7-2.62.62.62.6-2.6-2.2
Locomotion distance, session 81.72.53.0-1.71.71.71.7-1.71.71.6-1.51.51.51.6-1.6-0.2
Degree of sensitization distance0.10.10.2-0.50.30.30.3-0.30.30.2-0.30.30.30.2-0.2-0.3
Degree of sensitization stereotypy1.21.32.41.6-1.3-1.4-1.41.3-1.4-1.20.9-0.9-0.9-0.80.80.2
Conditioned locomotion0.20.20.30.6-0.5-0.5-0.50.5-0.5-0.50.5-0.5-0.5-0.40.40.3
Cocaine response after cond. corrected1.42.13.41.9-1.7-1.6-1.61.5-1.5-1.41.4-1.4-1.4-1.41.40.5
Cocaine response after cond. not corrected2.23.24.92.2-2.0-1.9-1.91.9-1.8-1.81.7-1.7-1.7-1.61.61.4
Cocaine response before conditioning0.81.04.10.9-0.8-0.8-0.80.9-0.8-1.10.9-0.9-0.9-0.60.62.0
Saline control response0.10.21.30.1-0.2-0.1-0.20.2-0.2-0.30.4-0.4-0.4-0.30.31.2
Bone: connectivity density2.13.44.32.1-2.0-2.0-2.02.0-2.0-2.01.7-1.7-1.7-1.81.81.1
Bone: cortical apparent density3.35.27.62.8-2.4-2.4-2.42.4-2.4-2.42.2-2.2-2.2-1.91.92.3
Bone: cortical area0.20.30.40.6-0.5-0.5-0.50.5-0.5-0.60.6-0.6-0.6-0.40.40.6
Bone: cortical porosity1.31.42.21.0-1.2-1.1-1.11.1-1.1-1.01.5-1.5-1.5-1.41.40.7
Bone: cortical porosity1.41.52.21.0-1.2-1.1-1.11.1-1.1-1.11.5-1.5-1.5-1.41.40.9
Bone: cortical thickness1.32.14.31.7-1.5-1.3-1.31.3-1.3-1.41.4-1.4-1.4-1.21.22.1
Bone: cortical thickness4.85.912.52.4-2.4-2.2-2.22.2-2.2-2.42.5-2.5-2.5-2.22.23.5
Bone: cortical tissue density3.35.27.62.8-2.4-2.3-2.42.4-2.3-2.42.1-2.1-2.1-1.91.92.3
Condit. Reinf. active minus inactive responses0.30.40.50.6-0.6-0.7-0.70.7-0.7-0.70.5-0.5-0.5-0.60.60.3
Condit. Reinf. active-inactive response ratio0.80.81.10.7-0.9-1.0-1.01.0-1.0-1.00.9-0.9-0.9-1.01.00.1
Condit. Reinf. active responses0.50.60.90.9-0.9-0.9-0.90.9-0.9-0.80.6-0.6-0.6-0.80.80.1
Condit. Reinf. inactive responses0.40.50.90.9-0.9-0.8-0.80.8-0.8-0.60.6-0.6-0.6-0.70.70.5
Incentive salience index mean1.11.41.61.2-1.3-1.2-1.21.2-1.2-1.21.2-1.2-1.2-1.21.20.8
Condit. Reinf. lever presses1.21.71.91.3-1.4-1.3-1.31.3-1.3-1.31.4-1.4-1.4-1.41.41.1
Condit. Reinf. active minus inactive responses0.60.91.80.8-0.9-0.8-0.80.8-0.8-0.81.1-1.1-1.1-1.01.01.3
Condit. Reinf. active-inactive response ratio0.20.30.50.7-0.6-0.6-0.60.6-0.6-0.50.6-0.6-0.6-0.60.60.0
Condit. Reinf. active responses1.11.63.11.0-1.2-1.1-1.11.1-1.1-1.21.4-1.4-1.4-1.41.41.7
Condit. Reinf. inactive responses1.82.74.51.4-1.6-1.5-1.51.5-1.5-1.61.7-1.7-1.7-1.71.72.1
Condit. Reinf. lever presses0.10.11.00.1-0.2-0.1-0.10.1-0.1-0.10.3-0.3-0.3-0.30.31.0
Condit. Reinf. lever reinforcers received1.21.63.71.0-1.2-1.0-1.11.1-1.1-1.11.4-1.4-1.4-1.41.41.9
Conditioned reinforcement - actives0.41.41.81.0-1.1-1.1-1.11.1-1.1-1.31.3-1.3-1.3-1.31.30.9
Conditioned reinforcement - inactives0.10.20.6-0.0-0.2-0.2-0.20.2-0.2-0.40.8-0.8-0.8-0.50.50.6
Conditioned locomotion1.62.43.51.3-1.6-1.5-1.51.5-1.5-1.51.7-1.7-1.7-1.91.90.3
Patch foraging indifference point 0 sec0.82.22.61.5-1.6-1.5-1.51.5-1.5-1.41.4-1.4-1.4-1.61.61.5
Patch foraging indifference point AUC0.10.30.90.10.20.20.2-0.20.20.5-0.60.60.60.7-0.7-1.0
Delay disc. indifference point, 0s delay2.02.35.41.4-1.5-1.4-1.41.4-1.4-1.41.5-1.5-1.5-1.41.42.3
Delay disc. indifference point, 16s delay0.40.50.80.9-0.7-0.7-0.80.8-0.8-0.80.5-0.5-0.5-0.60.60.9
Delay disc. indifference point, 2s delay3.03.47.01.7-1.8-1.6-1.61.6-1.6-1.71.9-1.9-1.9-1.81.82.7
Delay disc. indifference point, 24s delay0.10.10.30.40.1-0.0-0.00.0-0.00.0-0.30.30.30.6-0.6-0.0
Delay disc. indifference point, 4s delay1.11.29.80.7-0.7-0.5-0.50.5-0.5-0.80.9-0.9-0.9-0.60.63.1
Delay disc. indifference point, 8s delay0.61.11.50.9-0.8-0.9-0.90.9-0.9-1.21.2-1.2-1.2-1.01.01.2
Indifference point function ln k0.00.10.6-0.0-0.1-0.1-0.10.1-0.1-0.30.4-0.4-0.4-0.30.30.8
Indifference point function log k0.00.10.6-0.0-0.1-0.1-0.10.1-0.1-0.30.4-0.4-0.4-0.30.30.8
Patch foraging total patch changes 0 sec0.41.31.51.2-1.2-1.1-1.11.1-1.1-1.11.1-1.1-1.1-1.21.21.2
Patch foraging total patch changes 12 sec3.54.76.32.5-2.4-2.3-2.32.2-2.2-2.12.1-2.1-2.1-2.22.21.5
Patch foraging total patch changes 18 sec0.10.20.70.8-0.6-0.6-0.50.5-0.5-0.10.1-0.1-0.1-0.40.4-0.7
Patch foraging total patch changes 24 sec0.41.42.61.6-1.4-1.4-1.31.3-1.3-1.01.0-1.0-1.0-1.01.00.3
Patch foraging total patch changes 6 sec0.61.01.81.3-1.2-1.2-1.11.1-1.1-0.80.8-0.8-0.8-0.90.90.2
Patch foraging time to switch 0 sec0.00.10.20.1-0.3-0.2-0.20.2-0.2-0.20.4-0.4-0.4-0.50.50.0
Patch foraging water rate 0 sec0.00.00.10.10.1-0.0-0.00.0-0.0-0.1-0.20.20.20.3-0.3-0.2
Patch foraging water rate 12 sec0.10.50.7-0.80.80.80.8-0.80.80.7-0.70.70.70.8-0.80.5
Patch foraging water rate 18 sec0.51.25.80.6-0.8-0.7-0.80.8-0.8-1.11.1-1.1-1.1-0.90.92.4
Patch foraging water rate 24 sec0.30.40.50.7-0.5-0.6-0.60.7-0.6-0.60.6-0.6-0.6-0.60.60.6
Patch foraging water rate 6 sec0.71.01.41.2-1.0-1.1-1.11.1-1.1-1.10.9-0.9-0.9-0.80.80.7
Seeking ratio, delayed vs. immediate footshock0.30.41.7-0.70.50.40.4-0.40.40.6-0.70.70.70.6-0.6-1.3
Distance traveled before self-admin0.10.10.7-0.90.40.40.4-0.40.40.1-0.10.10.10.0-0.00.3
Distance traveled after self-admin0.50.91.3-1.11.00.90.9-0.90.90.6-1.01.01.00.8-0.8-1.1
Extensor digitorum longus weight7.831.234.1-5.75.85.75.7-5.75.75.8-5.75.75.75.6-5.6-3.8
Bone: elastic displacement0.00.00.10.2-0.2-0.2-0.20.2-0.2-0.00.2-0.2-0.2-0.30.3-0.0
Bone: elastic work0.00.00.30.1-0.00.10.1-0.10.10.10.0-0.0-0.00.0-0.00.5
Bone: endosteal estimation1.43.34.3-2.11.91.91.9-1.91.91.8-1.81.81.81.6-1.6-1.6
Bone: endosteal perimeter1.33.35.0-2.11.91.81.8-1.81.81.8-1.71.71.71.5-1.5-2.2
Epididymis fat weight0.00.10.3-0.30.40.40.3-0.30.30.3-0.50.50.50.4-0.4-0.0
Delta time in closed arm before/after self-admin4.23.94.8-2.22.12.02.0-2.02.01.9-2.12.12.11.9-1.9-1.4
Delta time in open arm before/after self-admin0.10.10.30.2-0.2-0.0-0.10.1-0.1-0.00.3-0.3-0.3-0.30.30.5
Diff in mean of infusions in LGA sessions0.00.10.3-0.60.30.30.2-0.20.20.1-0.10.10.10.0-0.0-0.1
Delay discount exponential model param0.71.04.1-0.90.70.70.8-0.80.81.0-1.01.01.00.8-0.8-2.0
Extinction: sum of active levers before priming0.60.91.6-0.91.10.80.8-0.70.80.6-1.11.11.11.2-1.2-0.1
Active lever presses in extinction session 60.10.10.4-0.00.3-0.1-0.00.1-0.1-0.1-0.50.50.50.5-0.5-0.6
Bone: final force1.11.82.21.5-1.4-1.4-1.41.4-1.4-1.41.3-1.3-1.3-1.31.31.3
Bone: final moment1.11.72.21.4-1.4-1.2-1.31.2-1.2-1.31.3-1.3-1.3-1.31.31.5
Food consumed during 24 hour testing period0.61.31.6-1.01.11.21.2-1.21.21.3-1.21.21.21.3-1.3-0.3
Glucose0.40.61.61.0-0.8-0.7-0.70.7-0.7-0.70.6-0.6-0.6-0.50.51.2
Heart weight3.04.96.3-2.52.42.12.2-2.22.22.2-2.12.12.12.1-2.1-2.3
Delay discount hyperbolic model param0.71.04.5-0.80.70.70.7-0.70.70.9-1.01.01.00.8-0.8-2.1
Intermittent access intake day 1-15 change0.00.21.2-0.50.50.30.3-0.30.30.1-0.20.20.20.4-0.4-1.1
Intermittent access intake escalation0.00.21.3-0.40.40.20.2-0.20.20.1-0.20.20.20.3-0.3-1.1
Intermittent access intake escalation 20.71.14.7-0.91.00.70.7-0.70.70.8-1.01.01.01.1-1.1-2.2
Intermitt. access day 1 inactive lever presses0.10.81.30.5-0.6-0.7-0.70.7-0.7-0.91.1-1.1-1.1-0.90.91.1
Intermitt. access day 15 inactive lever presses0.10.71.00.7-0.8-1.0-0.90.9-0.9-0.80.9-0.9-0.9-0.80.8-0.5
Intermitt. access escalation Index0.41.11.8-0.91.01.21.2-1.21.21.4-1.21.21.20.8-0.8-0.4
Intermittent access day 1 total infusions0.00.00.10.1-0.0-0.0-0.10.1-0.1-0.20.1-0.1-0.1-0.10.10.3
Intermittent access day 15 total infusions0.00.10.3-0.40.40.30.3-0.20.20.0-0.20.20.20.3-0.3-0.6
Intermittent access terminal intake (last 3 days)0.00.10.60.1-0.0-0.2-0.20.2-0.2-0.2-0.00.00.0-0.00.0-0.8
Intermittent access total infusions0.10.10.1-0.20.30.30.2-0.20.20.1-0.30.30.30.3-0.3-0.2
Intermittent access day 1 locomotion0.20.31.00.3-0.5-0.4-0.40.4-0.4-0.50.7-0.7-0.7-0.70.71.0
Intermittent access day 15 total locomotion0.20.81.30.6-0.7-0.9-0.90.9-0.9-1.11.1-1.1-1.1-0.70.70.1
Intermittent access total locomotion1.31.62.21.0-1.2-1.2-1.21.2-1.2-1.41.5-1.5-1.5-1.31.30.7
Intermittent access standard deviation0.00.10.60.2-0.2-0.3-0.30.4-0.4-0.40.2-0.2-0.2-0.10.1-0.8
Left kidney weight0.76.07.0-2.42.62.62.5-2.52.52.5-2.62.62.62.6-2.60.0
Right kidney weight0.10.81.1-0.70.90.90.9-0.90.91.0-1.01.01.01.0-1.00.4
Cocaine induced anxiety1.84.85.6-2.42.42.12.2-2.12.12.1-2.12.12.12.2-2.2-2.2
Post-drug Anxiety0.70.81.8-1.11.00.90.9-0.90.90.8-0.70.70.70.8-0.8-1.3
Baseline Anxiety2.54.24.82.1-2.1-2.0-2.02.0-2.0-1.92.2-2.2-2.2-2.02.01.6
Tail length1.89.617.3-2.63.03.33.2-3.13.22.5-2.82.82.83.3-3.34.2
Length with tail4.921.626.1-4.54.95.15.0-5.05.04.6-4.64.64.64.9-4.91.7
Length without tail1.910.212.2-3.33.33.43.4-3.33.43.5-3.23.23.23.2-3.2-1.4
Times rat made contact with spout0.70.81.11.0-1.0-0.9-0.90.9-0.9-0.70.9-0.9-0.9-0.80.80.9
Lifetime Intake0.00.00.0-0.10.20.10.1-0.10.1-0.0-0.20.20.20.1-0.1-0.0
Liver weight, left0.20.40.8-0.50.70.50.5-0.50.50.5-0.80.80.80.9-0.9-0.4
Liver weight, right0.20.31.90.7-0.4-0.5-0.50.5-0.5-0.60.3-0.3-0.30.1-0.11.4
Locomotor activity0.40.71.00.9-0.9-1.0-1.01.0-1.0-0.90.5-0.5-0.5-0.80.8-0.3
Locomotor testing distance1.84.55.72.1-2.2-2.4-2.42.4-2.4-2.42.0-2.0-2.0-2.22.20.2
Locomotor testing rearing1.65.87.42.7-2.5-2.7-2.72.7-2.7-2.72.1-2.1-2.1-2.22.21.3
Locomotion in novel chamber2.02.64.31.7-1.7-1.8-1.71.7-1.7-1.51.5-1.5-1.5-1.31.32.1
Locomotion in novel chamber post-restriction0.10.30.60.6-0.7-0.6-0.50.5-0.5-0.20.5-0.5-0.5-0.80.8-0.7
Fecal boli incidents, locomotor time 10.20.63.7-0.70.60.40.4-0.40.40.6-0.70.70.70.6-0.6-1.9
Change in fecal boli incidents, locomotor task0.50.52.00.7-0.6-0.6-0.60.6-0.6-0.70.7-0.7-0.7-0.50.51.4
Time >=10cm from walls, locomotor time 10.81.01.81.0-1.0-0.9-0.90.9-0.9-0.91.3-1.3-1.3-0.90.90.7
Bouts of movement, locomotor time 10.20.20.4-0.60.50.60.6-0.60.60.5-0.40.40.40.2-0.20.2
Total resting periods, locomotor time 10.30.30.6-0.70.60.80.7-0.70.70.6-0.50.50.50.3-0.30.3
Rest time, locomotor task time 10.10.10.6-0.0-0.10.10.1-0.20.20.30.2-0.2-0.2-0.40.40.8
Distance moved, locomotor task time 10.00.10.40.3-0.2-0.3-0.30.3-0.3-0.60.1-0.1-0.1-0.00.00.6
Vertical activity count, locomotor time 10.00.10.3-0.50.50.20.2-0.20.2-0.1-0.30.30.30.5-0.5-0.5
Time >=10cm from walls, locomotor time 20.72.13.41.3-1.3-1.3-1.31.3-1.3-1.41.6-1.6-1.6-1.31.31.9
Bouts of movement, locomotor time 20.10.20.40.2-0.3-0.4-0.40.4-0.4-0.60.4-0.4-0.4-0.60.60.2
Total resting periods, locomotor time 20.00.10.2-0.1-0.1-0.2-0.20.2-0.2-0.40.3-0.3-0.3-0.50.50.0
Rest time, locomotor task time 20.60.91.9-1.41.01.11.1-1.11.11.1-0.90.90.90.7-0.7-0.5
Distance moved, locomotor task time 20.10.10.90.10.10.10.1-0.10.1-0.0-0.30.30.30.3-0.31.0
Vertical activity count, locomotor time 20.00.10.7-0.20.30.20.2-0.20.2-0.1-0.00.00.00.2-0.20.8
Light reinforcement 10.73.24.11.7-1.8-1.7-1.71.7-1.7-1.71.9-1.9-1.9-2.02.00.8
Light reinforcement 20.40.81.11.0-0.9-0.9-0.90.9-0.9-0.81.0-1.0-1.0-0.90.90.7
Bone: marrow area1.33.14.1-2.01.91.91.8-1.81.81.8-1.71.71.71.6-1.6-1.5
Bone: maximum diameter0.00.10.50.1-0.1-0.1-0.10.1-0.1-0.10.1-0.1-0.1-0.20.2-0.7
Bone: maximum force0.00.00.10.2-0.2-0.1-0.20.2-0.2-0.20.2-0.2-0.2-0.10.10.4
Bone: maximum moment0.00.00.30.1-0.2-0.0-0.10.1-0.1-0.20.3-0.3-0.3-0.10.10.5
Mean time between licks in bursts0.32.02.6-1.61.51.51.5-1.51.51.6-1.31.31.31.2-1.2-1.2
Mean num. licks in bursts0.00.00.10.10.10.10.0-0.00.0-0.00.0-0.0-0.00.1-0.10.3
Cd content in liver0.80.91.6-1.31.11.00.9-1.00.90.7-0.80.80.80.8-0.8-1.1
Co content in liver2.22.62.9-1.61.71.61.6-1.61.61.5-1.71.71.71.6-1.6-1.0
Cu content in liver0.60.81.2-0.90.81.01.0-1.01.01.1-0.80.80.80.7-0.7-0.4
Fe content in liver2.02.52.9-1.61.61.71.7-1.71.71.7-1.61.61.61.5-1.5-0.5
K content in liver0.00.00.20.2-0.10.00.0-0.00.00.10.2-0.2-0.2-0.00.00.4
Mg content in liver0.10.21.90.3-0.2-0.1-0.10.1-0.0-0.00.2-0.2-0.20.0-0.01.4
Mn content in liver0.10.10.50.2-0.2-0.1-0.10.1-0.1-0.10.3-0.3-0.3-0.30.30.7
Na content in liver0.20.20.30.5-0.5-0.5-0.40.4-0.4-0.20.5-0.5-0.5-0.50.5-0.3
Rb content in liver1.41.71.91.1-1.3-1.3-1.31.3-1.3-1.31.3-1.3-1.3-1.41.41.1
Se content in liver2.83.34.52.1-2.0-2.0-1.91.9-1.9-1.81.8-1.8-1.8-1.81.80.8
Sr content in liver1.21.11.3-1.01.11.11.1-1.11.11.0-1.01.01.01.1-1.10.6
Zn content in liver1.61.92.21.2-1.4-1.3-1.31.3-1.3-1.31.5-1.5-1.5-1.51.51.3
Bone: minimum diameter0.40.81.0-1.01.01.00.9-0.90.90.8-0.90.90.91.0-1.0-0.5
Time in familiar zone, hab. session 10.40.40.60.5-0.5-0.7-0.70.7-0.7-0.80.6-0.6-0.6-0.50.5-0.3
Time in novel zone, hab. session 10.70.81.10.9-1.0-0.9-0.90.9-0.9-0.70.9-0.9-0.9-1.01.00.4
Total zone transitions, hab. session 12.23.14.0-1.81.92.02.0-2.02.01.8-1.71.71.71.8-1.80.5
Total locomotion distance, hab. session 10.10.11.6-0.20.10.30.2-0.20.20.10.0-0.0-0.0-0.00.01.3
Locomotion velocity, hab. session 10.60.81.5-1.00.91.01.0-1.01.00.8-0.70.70.70.7-0.71.2
Time in familiar zone, hab. session 20.70.81.00.6-0.8-0.9-0.90.9-0.9-1.00.9-0.9-0.9-1.01.0-0.4
Time in novel zone, hab. session 20.10.11.00.2-0.1-0.0-0.00.0-0.0-0.00.1-0.1-0.1-0.00.01.0
Total zone transitions, hab. session 20.50.60.9-1.00.91.00.9-0.90.90.8-0.70.70.70.8-0.80.1
Total locomotion distance, hab. session 20.00.10.2-0.40.30.30.3-0.30.30.2-0.10.10.10.1-0.1-0.0
Locomotion velocity, hab. session 20.20.20.4-0.70.60.60.5-0.50.50.4-0.40.40.40.4-0.40.0
Novel to familiar place preference ratio1.51.92.5-1.11.41.41.4-1.41.41.4-1.61.61.61.6-1.60.1
Novelty place preference0.91.21.6-0.81.11.11.1-1.11.11.0-1.31.31.31.3-1.30.4
Time in novel zone, NPP test0.30.40.6-0.40.60.60.6-0.60.60.5-0.70.70.70.8-0.80.7
Total zone transitions, NPP test0.40.61.7-0.70.70.90.8-0.80.80.7-0.40.40.40.6-0.61.3
Total locomotion distance, NPP test0.10.11.30.0-0.10.10.1-0.10.10.00.3-0.3-0.3-0.20.21.1
Locomotion velocity, NPP test0.30.40.8-0.60.60.80.7-0.70.70.7-0.40.40.40.4-0.40.9
Intraocular pressure1.42.22.9-1.61.71.41.4-1.41.41.1-1.61.61.61.7-1.7-0.6
Delta distance traveled before/after self-admin0.70.72.0-0.80.80.70.7-0.70.70.7-0.90.90.90.9-0.9-1.4
Delta ambulatory time before/after self-admin0.10.30.8-0.20.40.40.4-0.40.40.4-0.60.60.60.5-0.5-0.9
Parametrial fat weight0.51.32.21.0-1.0-1.0-1.11.1-1.1-1.21.1-1.1-1.1-1.11.11.5
Pavlov. Cond. lever latency2.43.13.3-1.81.81.81.8-1.81.81.8-1.71.71.71.7-1.7-1.5
Pavlov. Cond. magazine entry latency8.711.213.03.6-3.5-3.5-3.53.5-3.5-3.43.4-3.4-3.4-3.23.22.0
Pavlov. Cond. change in total contacts6.97.410.63.3-2.9-3.0-3.03.0-3.0-2.82.5-2.5-2.5-2.42.42.0
Pavlov. Cond. index score8.210.412.03.5-3.4-3.4-3.43.4-3.4-3.43.2-3.2-3.2-3.13.12.2
Pavlov. Cond. latency score6.38.09.43.1-3.0-3.0-3.03.0-3.0-2.92.8-2.8-2.8-2.72.72.1
Pavlov. Cond. lever contacts3.23.84.02.0-2.0-2.0-2.02.0-2.0-2.02.0-2.0-2.0-2.02.01.6
Pavlov. Cond. magazine entry number12.115.418.9-4.34.24.24.2-4.24.24.1-3.93.93.93.7-3.7-2.2
Pavlov. Cond. intertrial magazine entries1.41.72.1-1.31.31.41.4-1.41.41.4-1.31.31.31.2-1.2-0.3
Pavlov. Cond. lever-magazine prob. diff.9.611.913.93.7-3.6-3.6-3.63.6-3.6-3.63.4-3.4-3.4-3.33.32.3
Pavlov. Cond. response bias9.411.713.83.7-3.6-3.6-3.63.6-3.6-3.63.4-3.4-3.4-3.33.32.1
Pavlov. Cond. lever latency0.20.30.3-0.50.60.60.5-0.50.60.5-0.50.50.50.6-0.6-0.2
Pavlov. Cond. magazine entry latency0.10.10.8-0.20.20.30.3-0.30.30.3-0.10.10.10.2-0.20.9
Pavlov. Cond. change in total contacts0.30.60.90.6-0.8-0.7-0.70.7-0.7-0.70.9-0.9-0.9-0.90.90.4
Pavlov. Cond. index score0.10.20.30.4-0.4-0.4-0.30.3-0.3-0.30.4-0.4-0.4-0.40.40.5
Pavlov. Cond. latency score0.10.10.50.3-0.3-0.3-0.30.3-0.3-0.20.4-0.4-0.4-0.30.30.7
Pavlov. Cond. lever contacts0.40.60.70.7-0.8-0.8-0.80.8-0.8-0.70.8-0.8-0.8-0.80.80.3
Pavlov. Cond. magazine entry number0.20.31.3-0.40.50.30.4-0.40.30.4-0.60.60.60.5-0.5-1.1
Pavlov. Cond. intertrial magazine entries0.92.02.3-1.41.51.51.5-1.51.51.5-1.41.41.41.4-1.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.00.10.20.2-0.3-0.2-0.20.2-0.2-0.10.3-0.3-0.3-0.30.30.5
Pavlov. Cond. response bias0.70.91.11.0-1.1-1.0-1.01.0-1.0-0.91.0-1.0-1.0-1.01.00.5
Time in closed arm before self-admin1.52.73.41.7-1.8-1.6-1.61.6-1.6-1.41.7-1.7-1.7-1.91.90.6
Time in closed arm after self-admin0.30.30.6-0.70.60.60.6-0.60.60.7-0.50.50.50.5-0.5-0.8
Time in open arm before self-admin2.73.24.1-2.01.91.71.8-1.81.81.7-1.91.91.91.7-1.7-1.4
Time in open arm after self-admin0.40.50.6-0.70.70.70.7-0.70.70.7-0.70.70.70.6-0.6-0.1
Bone: periosteal estimation0.10.20.3-0.60.50.50.5-0.50.50.4-0.40.40.40.4-0.4-0.6
Bone: periosteal perimeter0.50.91.7-1.11.01.01.0-1.01.00.9-0.90.90.90.8-0.8-1.3
Bone: post-yield work0.40.71.3-1.10.90.90.9-0.90.90.8-0.60.60.60.7-0.7-0.4
Progressive ratio test 1 active lever presses0.40.62.20.9-0.8-0.6-0.70.7-0.7-0.80.6-0.6-0.6-0.70.71.5
Progressive ratio test 1 breakpoint0.40.61.90.9-0.8-0.6-0.70.7-0.7-0.80.6-0.6-0.6-0.70.71.4
Progressive ratio test 1 inactive lever presses0.10.20.40.1-0.2-0.2-0.20.2-0.2-0.40.6-0.6-0.6-0.50.50.7
Progressive ratio test 2 active lever presses0.30.40.60.7-0.6-0.7-0.70.7-0.7-0.80.6-0.6-0.6-0.40.40.5
Progressive ratio test 2 breakpoint0.40.50.70.7-0.7-0.7-0.70.7-0.7-0.80.7-0.7-0.7-0.50.50.7
Progressive ratio test 2 inactive lever presses0.10.30.5-0.60.60.40.5-0.40.40.3-0.50.50.50.7-0.7-0.4
Incentive Sensitization - Responses0.20.40.60.6-0.7-0.8-0.80.8-0.8-0.70.7-0.7-0.7-0.50.50.3
Incentive Sensitization - Breakpoint0.10.30.40.5-0.6-0.7-0.60.6-0.6-0.60.6-0.6-0.6-0.30.30.1
Sum of active levers in priming session hrs 5-60.10.10.40.30.0-0.2-0.30.3-0.3-0.4-0.10.10.10.4-0.40.6
Progressive ratio0.00.00.2-0.2-0.00.20.1-0.10.20.10.2-0.2-0.2-0.20.20.4
Food seeking constrained by brief footshock0.60.71.21.1-0.8-0.8-0.80.8-0.8-0.81.0-1.0-1.0-0.70.70.1
Seeking ratio, punishment vs. effort0.10.20.60.8-0.3-0.5-0.50.5-0.5-0.60.2-0.2-0.20.0-0.0-0.2
Retroperitoneal fat weight0.20.91.70.6-0.9-0.8-0.80.8-0.8-1.01.0-1.0-1.0-1.11.11.3
Reaction time number correct0.20.81.2-1.10.91.01.0-1.01.01.1-0.70.70.70.7-0.7-0.1
Reaction time mean minus median0.00.00.1-0.20.10.20.2-0.20.20.2-0.00.00.0-0.00.0-0.2
Reaction time mean minus median AUC0.10.60.90.6-0.8-0.7-0.70.7-0.7-0.60.8-0.8-0.8-0.90.90.3
Reaction time num false alarms0.40.71.00.9-0.9-0.9-0.90.9-0.9-1.00.8-0.8-0.8-0.80.80.7
Reaction time num false alarms AUC0.20.50.70.8-0.8-0.7-0.70.7-0.7-0.90.6-0.6-0.6-0.70.70.8
Reaction time trials correct on left0.20.81.2-1.10.91.01.0-1.01.01.1-0.70.70.70.7-0.7-0.1
Reaction time trials on left0.20.71.1-1.00.91.01.0-1.01.01.1-0.70.70.70.6-0.6-0.1
Reaction time mean0.00.10.90.1-0.1-0.2-0.10.1-0.10.00.1-0.1-0.1-0.20.2-0.9
Reaction time mean AUC0.00.11.0-0.1-0.1-0.1-0.10.1-0.10.10.0-0.0-0.0-0.10.1-1.0
Median of all reaction times0.20.31.00.4-0.5-0.6-0.50.5-0.5-0.30.3-0.3-0.3-0.40.4-1.0
Reaction time omissions0.30.50.80.8-0.8-0.6-0.70.7-0.7-0.70.7-0.7-0.7-0.70.70.9
Reaction time false alarm rate0.91.31.91.3-1.2-1.2-1.21.2-1.2-1.41.0-1.0-1.0-1.01.00.8
Reaction time premature initiation rate0.50.83.50.7-0.8-0.5-0.60.6-0.6-0.50.9-0.9-0.9-0.90.91.9
Reaction time premature initiations0.10.22.1-0.20.00.30.3-0.30.30.30.2-0.2-0.2-0.20.21.5
Std. dev. reaction times0.00.00.10.2-0.2-0.2-0.20.2-0.2-0.10.2-0.2-0.2-0.30.3-0.0
Reaction time trials completed0.20.71.1-1.00.91.01.0-1.01.01.1-0.70.70.70.6-0.6-0.1
Reaction time trials AUC0.20.61.0-0.90.80.90.9-0.90.91.0-0.60.60.60.5-0.5-0.1
Run reversals in cocaine runway, females1.21.31.9-1.41.31.21.2-1.21.20.9-1.11.11.11.3-1.3-0.4
Run reversals in cocaine runway, males0.40.41.7-0.0-0.4-0.7-0.60.6-0.6-0.50.7-0.7-0.7-0.60.6-1.3
Latency to leave start box in cocaine runway2.12.94.9-1.91.61.61.7-1.71.71.7-1.71.71.71.4-1.4-2.2
Latency to leave start box in cocaine runway, F2.53.24.1-2.01.71.81.9-1.91.92.0-1.81.81.81.3-1.3-2.0
Latency to leave start box in cocaine runway, M0.60.51.4-0.70.70.50.5-0.50.50.5-0.80.80.80.8-0.8-1.2
Std. dev. time between licks in bursts0.30.52.3-0.60.60.50.5-0.60.50.7-0.60.60.60.6-0.6-1.5
Total sessions with >9 infusions0.00.00.20.2-0.1-0.1-0.10.1-0.1-0.20.3-0.3-0.3-0.20.20.4
Short access day 1 total inactive lever presses0.71.43.91.0-1.0-0.9-1.01.0-1.0-1.21.2-1.2-1.2-1.11.12.0
Short access day 10 total inactive lever presses0.10.62.7-1.00.60.60.7-0.70.70.7-0.60.60.60.2-0.2-1.6
Short access day 1 total infusions0.00.00.00.1-0.1-0.1-0.10.2-0.2-0.20.1-0.1-0.1-0.10.10.0
Short access day 10 total infusions0.10.10.30.6-0.3-0.5-0.50.5-0.5-0.50.2-0.2-0.2-0.10.1-0.3
Short access total infusions0.00.00.00.00.10.10.0-0.00.00.0-0.20.20.20.1-0.1-0.1
Short access day 1 locomotion0.50.81.30.9-0.9-0.9-0.90.9-0.9-0.81.1-1.1-1.1-0.90.90.3
Short access day 10 total locomotion0.93.64.51.8-1.9-2.0-1.92.0-2.0-1.92.1-2.1-2.1-1.91.90.6
Short access total locomotion0.30.50.80.6-0.6-0.6-0.60.6-0.6-0.60.9-0.9-0.9-0.80.80.2
One hour access (0.3 mA shock)0.00.00.10.1-0.1-0.0-0.00.1-0.0-0.3-0.10.10.1-0.20.20.4
Compulsive drug intake0.40.64.60.7-0.6-0.2-0.30.3-0.3-0.40.4-0.4-0.4-0.60.62.1
One hour access (shock baseline)0.10.21.9-0.50.50.20.2-0.20.20.1-0.40.40.40.3-0.3-1.4
Social response proportion0.30.43.20.0-0.20.10.0-0.00.0-0.20.6-0.6-0.6-0.40.41.8
Social responses0.20.20.50.3-0.4-0.3-0.30.3-0.3-0.40.7-0.7-0.7-0.50.50.7
Social time0.10.11.30.00.1-0.0-0.00.0-0.00.1-0.00.00.00.1-0.1-1.2
Soleus weight0.41.22.01.4-1.2-1.2-1.21.2-1.2-1.10.9-0.9-0.9-1.01.00.7
Bone: stiffness0.10.10.40.2-0.3-0.1-0.20.2-0.2-0.30.4-0.4-0.4-0.30.30.6
Tibialis anterior weight1.34.55.2-2.12.22.22.2-2.22.22.3-2.22.22.22.3-2.3-0.6
Time to tail flick, vehicle, before self-admin0.20.31.10.6-0.3-0.5-0.50.5-0.5-0.80.4-0.4-0.4-0.20.21.1
Time to tail flick, vehicle, after self-admin0.00.10.60.3-0.1-0.3-0.20.2-0.2-0.20.1-0.1-0.1-0.00.0-0.7
Time to tail flick, test, before self-admin0.40.41.4-0.50.60.50.5-0.50.50.6-0.60.60.60.7-0.7-1.2
Time to tail flick, test, after self-admin0.10.10.20.4-0.1-0.3-0.30.3-0.3-0.2-0.10.10.10.1-0.1-0.2
Delta time to tail flick, vehicle, before/after SA0.40.40.60.7-0.7-0.7-0.70.7-0.7-0.40.6-0.6-0.6-0.60.6-0.8
Delta time to tail flick, test, before/after SA1.41.84.11.3-1.3-1.3-1.31.3-1.3-1.31.2-1.2-1.2-1.21.22.0
Tibia length0.72.12.6-1.31.41.51.5-1.51.51.5-1.61.61.61.5-1.5-0.4
Ambulatory time before self-admin0.10.51.5-1.20.80.80.8-0.80.80.6-0.50.50.50.4-0.4-0.2
Ambulatory time after self-admin1.62.52.9-1.71.71.61.5-1.51.51.3-1.71.71.71.6-1.6-1.5
Bone: tissue strength0.50.50.8-0.40.60.60.6-0.70.60.8-0.80.80.80.8-0.8-0.9
Total heroin consumption0.20.20.40.6-0.5-0.6-0.60.6-0.6-0.6-0.00.00.0-0.20.20.2
Bone: trabecular number4.17.79.13.0-3.0-2.9-2.92.9-2.9-2.92.7-2.7-2.7-2.82.81.5
Bone: trabecular spacing0.71.01.4-1.21.11.01.0-1.01.01.0-0.80.80.80.9-0.9-1.1
Bone: trabecular thickness0.00.00.00.2-0.1-0.1-0.10.1-0.10.0-0.20.20.20.1-0.1-0.1
Bone: trabecular tissue density0.00.00.1-0.00.10.10.1-0.10.10.1-0.10.10.10.2-0.20.2
Water consumed over 24 hours0.00.00.00.0-0.00.10.1-0.10.10.20.0-0.0-0.00.0-0.00.1
Number of responses in last shaping day0.20.31.4-0.20.40.30.3-0.30.30.4-0.50.50.50.6-0.6-1.2