Dtd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Dtd1 0.32 0.1 2.0e-14 0.33 0.35 0.34 0.35 1.1e-14 2.9e-15 5.6e-15 1.5e-15
2 Brain gene expression Dtd1 0.21 0.08 0.0e+00 0.19 0.19 0.19 0.2 8.5e-18 4.0e-17 1.9e-17 2.5e-18
3 PL gene expression Dtd1 0.16 0.07 5.6e-17 0.17 0.14 0.16 0.17 1.4e-18 4.0e-15 1.3e-17 6.2e-18
4 Liver gene expression Dtd1 0.21 0.09 2.8e-15 0.1 0.1 0.1 0.1 3.1e-11 1.6e-11 3.0e-11 4.4e-11
5 NAcc mRNA stability Dtd1 0.04 0.02 1.6e-04 0.03 0.01 0.01 -0 1.0e-05 8.3e-03 1.8e-03 6.2e-01
6 pVTA gene expression Dtd1 0.11 0.05 2.1e-11 0.11 0.13 0.12 0.11 5.8e-09 2.3e-10 8.9e-10 2.4e-09
7 Brain mRNA stability Dtd1 0.11 0.06 3.5e-09 0.08 0.07 0.09 0.09 8.0e-08 4.3e-07 2.4e-08 1.1e-08
8 Adipose gene expression Dtd1 0.33 0.12 0.0e+00 0.18 0.17 0.18 0.18 1.2e-19 6.5e-19 4.1e-19 1.1e-19
9 IL gene expression Dtd1 0.2 0.12 7.4e-03 0.09 0.01 0.05 -0 3.8e-03 1.5e-01 2.3e-02 3.6e-01
10 Liver mRNA stability Dtd1 0.06 0.05 1.2e-03 0.04 0.01 0.03 0.02 7.6e-05 6.7e-03 2.4e-04 1.4e-03
11 BLA gene expression Dtd1 0.26 0.13 3.1e-10 0.15 0.15 0.16 0.1 3.0e-08 2.7e-08 6.0e-09 7.7e-06
12 Brain intron excision ratio chr3_152449315_152453196 0.08 0.05 1.1e-04 0.05 0.02 0.03 0.04 3.4e-05 2.8e-03 1.5e-03 9.9e-05
13 IL mRNA stability Dtd1 0.24 0.12 1.7e-04 0.18 0.15 0.12 0.13 4.5e-05 2.3e-04 9.4e-04 4.4e-04
14 NAcc gene expression Dtd1 0.45 0.1 0.0e+00 0.22 0.27 0.28 0.22 7.3e-32 3.7e-40 3.4e-43 1.1e-32
15 RMTg gene expression Dtd1 0.17 0.09 4.7e-04 0.08 0.06 0.08 0.04 3.6e-03 1.1e-02 3.5e-03 2.5e-02
16 LHb mRNA stability Dtd1 0.63 0.19 1.1e-03 0.13 0.17 0.21 0.17 4.9e-04 6.1e-05 9.7e-06 7.1e-05
17 Brain intron excision ratio chr3_152453286_152466614 0.04 0.04 7.6e-03 0 0 0.01 0.01 2.4e-01 1.5e-01 7.9e-02 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.10.21.3-0.4-0.4-0.0-0.1-0.0-0.3-0.3-0.3-0.1-0.1-0.5-0.1-0.5-0.0-0.6-0.31.1
Area under the delay curve1.01.13.2-1.4-1.3-1.2-0.8-1.2-1.1-1.5-1.0-0.9-0.9-1.50.1-0.4-1.80.1-0.9-0.4
BMI with tail9.031.237.25.96.15.96.15.76.05.95.76.06.05.35.95.93.65.25.2-3.7
BMI without tail7.924.029.35.35.45.35.44.95.25.15.25.35.34.85.44.93.54.24.0-3.3
Body weight10.043.855.87.27.57.57.27.26.96.96.97.37.36.46.86.55.45.55.3-3.4
Weight adjusted by age0.30.42.0-0.6-0.4-0.0-0.6-0.0-0.8-0.3-0.7-0.4-0.4-0.5-0.5-0.91.0-0.90.11.4
Bone surface0.30.61.11.00.80.90.90.91.01.00.80.60.61.00.60.30.40.10.50.4
Bone volume0.10.21.10.30.30.60.30.60.30.30.30.20.20.30.2-0.40.5-0.5-0.01.1
Breakpoint value in progressive ratio session0.70.82.21.00.90.80.80.81.11.11.10.60.61.50.60.90.90.80.6-0.8
Number of licking bursts0.10.21.0-0.20.00.40.20.3-0.2-0.10.30.50.5-0.40.40.10.30.50.1-1.0
Context. condit. distance diff. score0.10.10.50.20.30.40.20.40.20.30.20.20.20.30.00.20.70.00.30.4
Locomotion velocity, session 11.01.12.8-0.7-1.0-1.2-1.1-1.2-0.6-0.6-0.9-1.3-1.3-0.2-1.4-1.7-0.4-1.1-0.81.0
Locomotion distance, session 14.35.47.4-2.4-2.5-2.5-2.5-2.5-2.4-2.4-2.3-2.4-2.4-2.2-2.2-2.7-2.3-2.1-2.41.1
Locomotion velocity, session 22.52.95.5-1.7-2.0-2.1-1.5-2.1-1.4-1.9-1.6-1.7-1.7-1.6-1.1-1.7-2.4-1.1-2.00.5
Locomotion distance, session 25.07.012.2-2.4-2.5-2.5-2.8-2.5-2.5-2.4-2.4-2.8-2.8-2.1-2.8-3.5-1.4-3.2-3.42.5
Locomotion velocity, session 32.93.34.4-2.1-2.1-1.9-2.0-1.9-2.0-2.0-2.0-1.8-1.8-1.8-1.8-2.0-1.4-1.6-1.11.0
Locomotion distance, session 31.11.21.9-1.4-1.4-1.2-1.1-1.1-1.2-1.3-1.2-1.0-1.0-1.2-1.0-0.9-1.2-0.8-0.70.4
Stereotopy head waving bouts, day 30.00.00.50.10.0-0.0-0.1-0.00.10.30.0-0.2-0.20.2-0.1-0.70.1-0.30.00.2
Stereotopy head waving duration, day 30.10.10.40.50.40.30.20.30.40.60.30.20.20.60.1-0.30.5-0.00.40.2
Locomotion velocity, session 71.41.52.2-1.4-1.3-1.1-1.4-1.2-1.5-1.4-1.3-1.2-1.2-1.3-1.3-1.3-0.8-1.1-1.20.9
Locomotion distance, session 70.20.30.7-0.6-0.4-0.2-0.7-0.3-0.8-0.7-0.4-0.5-0.5-0.6-0.6-0.8-0.1-0.7-0.50.5
Stereotopy head waving bouts, day 70.10.10.30.10.10.30.40.30.30.20.30.40.40.10.5-0.2-0.40.10.3-0.5
Stereotopy head waving duration, day 70.10.10.4-0.3-0.4-0.3-0.2-0.3-0.1-0.2-0.3-0.2-0.2-0.2-0.2-0.6-0.4-0.4-0.00.3
Locomotion velocity, session 80.81.01.7-0.7-0.9-1.1-1.1-1.1-0.7-0.7-0.8-1.2-1.2-0.3-1.3-1.3-0.5-1.2-1.11.1
Locomotion distance, session 82.33.35.4-1.7-1.7-1.6-2.0-1.7-1.9-1.7-1.7-1.9-1.9-1.5-2.0-2.3-0.8-2.2-2.01.8
Degree of sensitization distance0.40.40.80.80.90.90.50.80.40.60.80.60.60.50.40.10.90.00.10.1
Degree of sensitization stereotypy0.40.40.70.60.50.80.70.80.70.60.60.80.80.60.70.20.20.20.8-0.3
Conditioned locomotion0.20.21.20.10.00.0-0.30.0-0.10.1-0.2-0.3-0.30.3-0.7-0.41.0-0.8-0.11.1
Cocaine response after cond. corrected1.72.03.3-1.4-1.3-1.1-1.5-1.1-1.7-1.6-1.2-1.3-1.3-1.6-1.6-1.7-0.7-1.6-1.81.2
Cocaine response after cond. not corrected3.13.65.1-2.0-1.8-1.4-2.0-1.4-2.3-2.1-1.8-1.8-1.8-2.2-2.0-2.2-0.8-2.0-2.22.1
Cocaine response before conditioning0.30.31.6-0.6-0.6-0.5-0.4-0.3-0.5-0.6-0.7-0.6-0.6-0.6-0.3-0.3-0.2-0.3-0.51.3
Saline control response0.81.14.11.31.21.10.51.10.71.10.90.40.41.30.1-0.52.0-1.0-0.01.6
Bone: connectivity density0.10.20.7-0.4-0.5-0.5-0.3-0.5-0.2-0.3-0.5-0.5-0.5-0.4-0.3-0.2-0.7-0.5-0.40.8
Bone: cortical apparent density0.30.41.0-0.5-0.5-0.9-0.5-0.7-0.4-0.4-0.8-0.6-0.6-0.6-0.30.4-1.00.41.0-0.5
Bone: cortical area0.20.31.10.30.40.20.50.30.50.40.20.30.30.20.80.9-0.10.71.0-0.4
Bone: cortical porosity0.40.40.80.70.60.40.60.30.80.80.70.60.60.70.70.70.40.70.6-0.9
Bone: cortical porosity0.70.71.11.00.90.70.80.61.01.00.90.70.70.90.90.90.60.81.0-0.8
Bone: cortical thickness0.40.63.20.20.2-0.30.5-0.20.60.3-0.20.30.30.11.01.5-0.71.41.8-1.0
Bone: cortical thickness0.91.12.1-1.4-1.3-1.3-1.0-1.3-1.1-1.4-1.4-0.8-0.8-1.4-0.5-0.3-1.4-0.30.30.2
Bone: cortical tissue density0.20.30.9-0.5-0.4-0.8-0.5-0.7-0.4-0.4-0.8-0.5-0.5-0.5-0.30.3-0.90.20.9-0.4
Condit. Reinf. active minus inactive responses0.10.10.8-0.1-0.00.20.00.3-0.2-0.20.10.20.2-0.2-0.2-0.30.2-0.4-0.90.5
Condit. Reinf. active-inactive response ratio0.10.10.6-0.3-0.20.1-0.10.2-0.4-0.3-0.00.10.1-0.4-0.3-0.20.3-0.4-0.80.5
Condit. Reinf. active responses0.10.10.7-0.2-0.2-0.1-0.2-0.0-0.3-0.4-0.10.00.0-0.5-0.2-0.6-0.1-0.4-0.90.5
Condit. Reinf. inactive responses0.00.00.10.1-0.0-0.2-0.1-0.20.1-0.00.0-0.2-0.20.00.1-0.2-0.40.2-0.0-0.2
Incentive salience index mean0.40.51.8-0.8-0.8-0.6-0.4-0.6-0.7-1.0-0.5-0.2-0.2-1.1-0.3-0.5-1.0-0.3-1.30.3
Condit. Reinf. lever presses0.50.73.0-0.9-0.9-0.7-0.2-0.7-0.6-1.2-0.5-0.0-0.0-1.30.3-0.0-1.70.6-1.0-0.6
Condit. Reinf. active minus inactive responses1.31.73.01.61.61.41.21.41.51.61.31.21.21.70.91.21.50.80.90.3
Condit. Reinf. active-inactive response ratio1.31.52.21.51.41.41.21.41.31.41.51.21.21.50.91.01.20.80.2-0.1
Condit. Reinf. active responses1.01.43.21.31.20.91.10.91.31.30.81.11.11.41.01.50.71.31.8-0.4
Condit. Reinf. inactive responses0.30.53.90.10.1-0.20.3-0.20.40.3-0.30.30.30.30.70.9-0.50.92.0-0.8
Condit. Reinf. lever presses3.65.07.12.72.62.42.32.52.52.62.32.32.32.61.92.12.31.61.7-0.3
Condit. Reinf. lever reinforcers received1.31.83.01.51.41.11.31.21.61.61.11.21.21.71.11.61.01.31.7-0.4
Conditioned reinforcement - actives0.81.44.4-0.6-0.6-0.7-1.2-0.5-1.0-0.7-0.5-1.3-1.3-0.3-1.6-1.60.2-1.8-2.11.7
Conditioned reinforcement - inactives1.01.54.5-0.7-0.6-0.7-1.5-0.5-1.3-0.7-0.8-1.5-1.5-0.3-2.1-1.30.7-1.6-1.61.8
Conditioned locomotion0.30.31.0-0.5-0.7-0.8-0.6-0.6-0.4-0.6-0.4-0.7-0.7-0.2-0.6-0.2-0.5-0.3-1.00.5
Patch foraging indifference point 0 sec0.30.62.9-0.4-0.1-0.0-0.8-0.0-0.8-0.1-0.5-0.6-0.6-0.1-1.1-1.00.7-1.3-0.01.7
Patch foraging indifference point AUC0.60.91.7-1.1-1.2-1.3-0.9-1.0-0.8-1.1-1.2-0.9-0.9-0.8-0.7-0.5-1.2-0.3-0.3-0.3
Delay disc. indifference point, 0s delay0.50.51.90.30.20.20.70.30.50.00.70.60.6-0.01.11.0-0.91.3-0.2-1.4
Delay disc. indifference point, 16s delay1.61.72.8-1.6-1.6-1.4-1.2-1.4-1.4-1.6-1.3-1.3-1.3-1.7-0.6-1.1-1.7-0.7-1.20.2
Delay disc. indifference point, 2s delay0.50.51.80.20.20.50.80.40.50.00.80.80.8-0.01.30.7-0.61.0-0.3-1.3
Delay disc. indifference point, 24s delay4.75.38.4-2.9-2.7-2.4-2.3-2.4-2.7-2.9-2.4-2.3-2.3-2.9-1.4-1.8-2.5-1.3-1.80.6
Delay disc. indifference point, 4s delay0.30.31.8-0.2-0.10.10.4-0.2-0.0-0.40.20.50.5-0.61.10.4-0.90.80.1-1.3
Delay disc. indifference point, 8s delay1.11.22.1-1.4-1.4-1.5-1.1-1.4-1.1-1.3-1.2-1.2-1.2-1.1-0.6-0.8-1.3-0.4-0.70.2
Indifference point function ln k0.10.21.6-0.00.10.2-0.30.1-0.30.1-0.1-0.3-0.3-0.0-0.5-0.30.5-0.5-0.21.3
Indifference point function log k0.10.21.6-0.00.10.2-0.30.1-0.30.1-0.1-0.3-0.3-0.0-0.5-0.30.5-0.5-0.21.3
Patch foraging total patch changes 0 sec0.40.83.3-0.6-0.3-0.2-1.0-0.3-0.9-0.3-0.7-0.8-0.8-0.2-1.3-1.20.6-1.5-0.21.8
Patch foraging total patch changes 12 sec0.10.10.90.00.20.10.10.30.10.0-0.10.10.10.20.50.1-0.20.30.9-0.4
Patch foraging total patch changes 18 sec0.91.32.1-1.2-1.1-1.1-1.4-0.8-1.4-1.0-1.4-1.3-1.3-0.9-1.4-1.2-0.1-1.5-0.51.2
Patch foraging total patch changes 24 sec0.10.10.4-0.4-0.3-0.2-0.3-0.1-0.4-0.3-0.3-0.2-0.2-0.2-0.3-0.60.4-0.6-0.30.3
Patch foraging total patch changes 6 sec0.20.30.7-0.6-0.3-0.1-0.60.1-0.8-0.5-0.5-0.3-0.3-0.5-0.6-0.80.1-0.8-0.10.8
Patch foraging time to switch 0 sec1.22.43.61.51.61.51.81.41.61.41.81.71.71.11.91.60.51.60.9-1.8
Patch foraging water rate 0 sec1.42.94.0-1.9-1.8-1.7-1.9-1.8-1.9-1.7-2.0-1.9-1.9-1.4-2.0-1.6-0.9-1.6-0.91.5
Patch foraging water rate 12 sec2.45.07.2-2.5-2.5-2.4-2.3-2.4-2.5-2.7-2.7-2.2-2.2-2.6-2.0-1.8-1.8-1.6-1.61.3
Patch foraging water rate 18 sec9.214.217.6-4.0-3.9-3.6-3.9-3.7-4.2-4.2-3.6-3.9-3.9-3.9-3.7-3.9-2.7-3.8-3.92.7
Patch foraging water rate 24 sec3.65.07.2-2.4-2.2-1.9-2.5-1.9-2.7-2.5-2.1-2.5-2.5-2.1-2.6-2.4-0.9-2.3-2.11.7
Patch foraging water rate 6 sec4.46.48.1-2.8-2.7-2.7-2.8-2.7-2.8-2.8-2.9-2.7-2.7-2.5-2.5-2.6-1.5-2.5-1.41.9
Seeking ratio, delayed vs. immediate footshock0.30.30.80.80.70.60.50.40.70.80.90.40.40.80.00.20.10.20.0-0.7
Distance traveled before self-admin0.30.32.40.20.10.30.50.20.40.20.50.60.60.10.90.4-0.50.80.3-1.5
Distance traveled after self-admin0.20.31.1-0.6-0.6-0.6-0.4-0.6-0.2-0.2-0.6-0.3-0.3-0.0-0.2-0.2-0.60.21.0-0.9
Extensor digitorum longus weight0.10.20.60.60.60.70.50.50.50.60.60.30.30.70.30.40.8-0.10.10.4
Bone: elastic displacement0.60.62.00.70.50.30.70.20.90.60.50.60.60.80.90.9-0.61.01.1-1.4
Bone: elastic work2.73.55.51.91.81.72.11.62.11.71.91.91.91.72.31.80.32.01.9-2.0
Bone: endosteal estimation1.53.47.22.12.22.71.92.51.71.82.51.81.81.81.50.32.40.3-0.60.4
Bone: endosteal perimeter0.40.83.01.01.01.30.61.20.50.91.10.50.50.90.1-0.51.7-0.7-0.71.0
Epididymis fat weight8.629.337.06.16.06.15.86.05.85.85.95.85.85.45.35.05.04.63.9-2.5
Delta time in closed arm before/after self-admin0.20.20.4-0.4-0.4-0.4-0.5-0.1-0.5-0.5-0.4-0.5-0.5-0.4-0.6-0.3-0.2-0.4-0.70.4
Delta time in open arm before/after self-admin2.92.93.91.81.81.91.71.91.71.81.71.91.91.61.71.62.01.51.4-0.9
Diff in mean of infusions in LGA sessions0.30.42.3-0.1-0.2-0.10.4-0.10.2-0.30.10.40.4-0.50.80.6-1.31.00.2-1.5
Delay discount exponential model param1.31.43.41.61.51.30.91.41.31.61.11.01.01.70.10.61.90.11.00.3
Extinction: sum of active levers before priming0.20.21.1-0.3-0.4-0.5-0.5-0.4-0.4-0.4-0.2-0.6-0.6-0.1-0.7-0.4-0.1-0.4-1.00.1
Active lever presses in extinction session 62.22.24.61.71.61.31.41.51.81.91.51.01.02.11.21.51.21.31.6-0.9
Bone: final force0.20.41.00.50.60.70.70.70.60.40.70.70.70.31.00.10.40.60.7-0.4
Bone: final moment0.20.30.80.40.50.70.70.60.50.40.60.70.70.30.9-0.00.40.40.7-0.2
Food consumed during 24 hour testing period0.10.10.5-0.10.00.10.20.1-0.0-0.20.50.30.3-0.40.60.0-0.7-0.1-0.7-0.4
Glucose0.81.22.41.51.41.21.01.41.21.31.20.90.91.60.71.01.10.60.50.3
Heart weight1.21.83.11.51.61.51.41.41.61.71.51.21.21.81.20.91.40.91.1-0.4
Delay discount hyperbolic model param0.70.82.41.21.10.90.61.00.91.20.80.60.61.3-0.20.31.6-0.20.80.5
Intermittent access intake day 1-15 change0.61.32.01.21.21.41.11.41.21.31.41.21.21.20.61.31.30.90.1-0.2
Intermittent access intake escalation0.40.81.40.90.91.00.91.10.91.01.10.90.90.90.41.21.00.80.0-0.2
Intermittent access intake escalation 21.21.42.51.11.31.41.11.61.01.21.41.31.30.90.81.61.31.20.1-0.7
Intermitt. access day 1 inactive lever presses0.31.24.3-0.8-0.8-0.7-1.0-0.6-1.0-0.8-1.0-1.1-1.1-0.8-1.3-1.1-0.2-1.5-1.32.1
Intermitt. access day 15 inactive lever presses0.30.62.40.80.90.8-0.00.90.20.80.4-0.0-0.00.7-0.6-0.01.4-0.6-0.31.5
Intermitt. access escalation Index0.60.92.51.10.80.70.90.51.21.30.60.80.81.30.70.51.40.61.60.3
Intermittent access day 1 total infusions0.00.10.20.1-0.0-0.20.00.10.20.0-0.2-0.1-0.10.50.40.1-0.00.10.40.3
Intermittent access day 15 total infusions0.50.71.50.90.90.80.81.01.01.00.70.70.71.20.81.10.80.80.70.1
Intermittent access terminal intake (last 3 days)0.91.22.01.11.11.01.11.21.21.20.91.01.01.41.21.31.01.30.9-0.5
Intermittent access total infusions0.70.82.21.11.00.80.81.11.11.10.90.70.71.50.70.81.00.70.7-0.1
Intermittent access day 1 locomotion0.30.31.0-0.5-0.7-1.0-0.4-0.8-0.3-0.7-0.8-0.6-0.6-0.30.1-0.3-0.9-0.1-0.20.3
Intermittent access day 15 total locomotion0.40.71.21.10.90.70.81.11.00.90.70.70.71.00.71.11.10.70.10.2
Intermittent access total locomotion0.00.00.10.1-0.1-0.30.0-0.00.2-0.1-0.1-0.0-0.00.30.20.3-0.00.3-0.30.1
Intermittent access standard deviation0.00.10.5-0.1-0.0-0.0-0.10.20.00.10.3-0.0-0.00.3-0.30.30.20.3-0.7-0.2
Left kidney weight1.25.68.12.82.72.52.72.42.82.72.52.42.42.72.22.12.11.61.5-0.7
Right kidney weight0.41.72.91.71.61.51.51.21.61.71.61.31.31.60.90.91.50.50.30.1
Cocaine induced anxiety0.20.31.0-0.2-0.4-0.5-0.5-0.5-0.2-0.1-0.6-0.7-0.70.0-0.8-0.70.1-0.70.11.0
Post-drug Anxiety0.50.51.00.80.80.80.61.00.70.70.50.60.60.70.40.70.70.70.9-0.3
Baseline Anxiety2.83.35.71.61.82.01.92.21.51.41.82.02.01.21.92.40.92.21.2-2.1
Tail length0.41.72.71.41.61.61.31.51.21.31.41.51.51.31.40.91.60.70.6-0.5
Length with tail1.87.912.03.23.33.53.03.42.73.03.03.13.12.92.52.03.41.61.4-0.6
Length without tail1.75.49.72.62.72.72.53.12.32.62.32.52.52.31.92.02.61.51.60.0
Times rat made contact with spout3.23.75.32.32.12.12.12.12.22.12.31.91.92.11.91.91.21.60.7-0.9
Lifetime Intake0.50.71.80.90.80.80.71.01.01.00.90.70.71.30.60.70.90.60.4-0.1
Liver weight, left1.62.65.11.71.92.21.62.11.51.81.71.81.81.61.30.92.30.61.30.0
Liver weight, right1.62.74.42.02.12.11.81.91.61.81.91.81.81.61.31.71.60.90.8-0.4
Locomotor activity0.10.20.40.60.50.40.50.60.60.50.50.30.30.60.60.60.20.40.0-0.5
Locomotor testing distance0.00.10.2-0.1-0.1-0.4-0.2-0.2-0.0-0.1-0.1-0.3-0.3-0.00.10.2-0.30.2-0.5-0.2
Locomotor testing rearing0.20.40.70.70.70.50.50.60.70.70.80.40.40.80.40.70.60.6-0.3-0.5
Locomotion in novel chamber1.31.64.7-0.9-0.9-1.0-1.4-0.8-1.1-0.7-1.3-1.3-1.3-0.4-2.1-1.70.4-1.8-0.72.2
Locomotion in novel chamber post-restriction1.52.44.7-1.5-1.4-1.5-1.7-1.3-1.6-1.3-1.7-1.6-1.6-1.1-1.7-2.2-0.3-2.0-1.21.7
Fecal boli incidents, locomotor time 11.21.73.8-1.2-1.1-1.0-1.4-1.2-1.4-1.3-0.9-1.2-1.2-1.1-1.2-1.90.4-1.8-1.81.3
Change in fecal boli incidents, locomotor task0.10.10.70.20.0-0.0-0.0-0.20.30.4-0.2-0.2-0.20.4-0.3-0.1-0.2-0.10.90.7
Time >=10cm from walls, locomotor time 10.40.41.1-0.6-0.6-0.4-0.5-0.4-0.5-0.5-0.6-0.6-0.6-0.5-0.7-0.7-0.7-1.0-0.41.0
Bouts of movement, locomotor time 12.42.87.5-1.7-1.6-1.4-1.6-1.6-1.9-1.9-1.2-1.4-1.4-2.0-1.2-1.9-1.2-1.7-2.70.6
Total resting periods, locomotor time 13.33.69.3-1.9-1.9-1.5-1.9-1.9-2.1-2.2-1.5-1.7-1.7-2.2-1.6-2.2-1.2-2.0-3.00.8
Rest time, locomotor task time 10.91.26.9-0.8-0.8-0.3-0.9-0.6-1.2-1.2-0.3-0.6-0.6-1.2-1.0-1.40.0-1.4-2.60.6
Distance moved, locomotor task time 10.60.94.7-1.0-1.0-1.3-0.6-1.2-0.4-0.7-1.1-1.0-1.0-0.8-0.10.0-2.20.30.7-0.5
Vertical activity count, locomotor time 10.20.41.10.60.60.40.90.30.80.70.50.70.70.51.00.8-0.30.60.8-0.2
Time >=10cm from walls, locomotor time 20.91.32.41.31.21.41.21.51.31.21.31.11.11.21.01.21.00.80.4-0.2
Bouts of movement, locomotor time 20.10.21.20.40.3-0.00.30.30.50.50.40.10.10.60.50.2-0.20.60.1-1.1
Total resting periods, locomotor time 20.10.20.90.50.40.10.40.40.60.70.50.20.20.70.40.20.00.60.2-1.0
Rest time, locomotor task time 20.10.10.3-0.4-0.3-0.1-0.4-0.2-0.5-0.3-0.0-0.3-0.3-0.5-0.5-0.6-0.4-0.4-0.4-0.4
Distance moved, locomotor task time 20.70.82.2-0.9-1.0-1.2-0.7-1.0-0.8-1.1-1.0-0.9-0.9-1.1-0.5-0.1-1.5-0.1-1.1-0.1
Vertical activity count, locomotor time 20.00.10.30.1-0.0-0.10.2-0.00.2-0.10.00.10.1-0.00.20.5-0.40.2-0.50.1
Light reinforcement 10.10.31.7-0.10.0-0.0-0.4-0.0-0.5-0.2-0.0-0.3-0.3-0.2-0.5-1.10.6-1.0-1.30.8
Light reinforcement 20.40.62.70.50.30.0-0.4-0.20.00.60.1-0.5-0.50.9-1.1-1.31.7-1.2-0.31.0
Bone: marrow area1.53.37.02.12.22.71.92.51.71.82.41.81.81.81.40.32.40.3-0.60.5
Bone: maximum diameter0.51.02.11.11.31.51.01.40.81.01.21.01.00.80.90.81.40.20.30.3
Bone: maximum force0.10.20.80.40.50.70.60.60.40.40.50.60.60.20.9-0.10.30.20.30.0
Bone: maximum moment0.10.20.70.30.40.70.60.60.40.30.50.60.60.10.9-0.20.20.20.40.0
Mean time between licks in bursts0.20.41.9-0.5-0.5-0.5-0.5-0.6-0.5-0.4-0.7-0.4-0.4-0.4-0.7-1.40.1-1.10.50.9
Mean num. licks in bursts0.50.81.71.31.10.70.90.91.31.10.90.50.51.30.71.00.20.30.10.6
Cd content in liver0.20.20.8-0.4-0.10.40.00.4-0.6-0.70.10.40.4-0.90.2-0.30.1-0.2-0.9-0.1
Co content in liver0.50.60.9-0.8-0.8-0.8-0.9-0.7-0.8-0.8-0.9-0.8-0.8-0.6-0.8-0.6-0.3-0.7-0.70.9
Cu content in liver0.70.91.4-1.1-1.0-1.0-1.0-0.9-1.1-1.2-0.9-1.0-1.0-1.1-0.6-0.7-1.2-0.5-0.80.0
Fe content in liver1.21.42.41.21.20.91.31.11.31.21.41.01.01.01.41.50.31.50.6-1.5
K content in liver1.51.54.1-1.4-1.5-1.6-1.1-1.7-1.0-1.4-1.5-1.1-1.1-1.3-0.6-0.4-2.00.10.2-0.7
Mg content in liver0.10.11.10.10.1-0.10.0-0.20.10.2-0.2-0.0-0.00.2-0.00.4-0.20.31.0-0.5
Mn content in liver1.11.24.1-0.5-0.7-0.7-1.1-0.8-0.6-0.3-1.1-1.2-1.20.2-1.6-1.60.6-1.60.52.0
Na content in liver0.60.62.70.50.3-0.10.6-0.01.00.70.30.20.20.70.71.6-0.71.40.9-1.1
Rb content in liver0.10.10.4-0.10.20.30.30.3-0.0-0.00.10.30.3-0.40.60.3-0.50.40.3-0.6
Se content in liver0.30.31.00.10.10.10.5-0.10.3-0.10.20.50.5-0.10.90.8-0.91.00.7-0.9
Sr content in liver0.80.71.5-0.8-0.8-0.6-0.9-0.8-0.8-0.6-0.8-0.9-0.9-0.6-0.9-1.20.1-1.2-0.61.2
Zn content in liver0.50.51.3-0.8-0.8-1.0-0.5-1.1-0.6-0.9-0.6-0.6-0.6-1.0-0.20.1-1.1-0.0-0.9-0.4
Bone: minimum diameter0.40.81.21.11.01.01.00.91.11.00.90.80.81.00.90.80.80.50.80.1
Time in familiar zone, hab. session 10.30.30.70.20.20.20.60.20.3-0.00.30.70.7-0.30.80.5-0.90.8-0.3-0.6
Time in novel zone, hab. session 10.30.32.20.50.50.50.20.60.40.70.50.20.20.9-0.20.31.5-0.30.40.3
Total zone transitions, hab. session 11.11.53.4-1.2-1.3-1.3-1.3-1.4-1.2-1.2-1.0-1.2-1.2-1.2-1.1-1.8-1.2-0.9-1.80.1
Total locomotion distance, hab. session 11.92.85.1-1.6-1.6-1.9-1.7-2.0-1.6-1.6-1.5-1.9-1.9-1.6-1.5-1.6-1.6-1.2-2.30.4
Locomotion velocity, hab. session 12.43.44.7-1.8-1.9-2.1-1.9-2.2-1.8-1.8-1.8-2.0-2.0-1.9-1.7-1.9-1.9-1.5-2.00.6
Time in familiar zone, hab. session 20.20.20.80.1-0.1-0.3-0.3-0.4-0.00.0-0.2-0.4-0.40.1-0.6-0.30.1-0.5-0.90.7
Time in novel zone, hab. session 20.60.61.30.70.71.00.81.10.60.70.80.90.90.70.90.60.80.70.8-0.6
Total zone transitions, hab. session 20.30.31.40.0-0.10.0-0.2-0.1-0.10.00.1-0.3-0.30.0-0.5-1.20.6-1.0-1.21.0
Total locomotion distance, hab. session 21.01.34.7-0.3-0.5-0.6-0.9-0.7-0.5-0.3-0.5-1.2-1.2-0.1-1.4-1.60.6-1.9-1.82.2
Locomotion velocity, hab. session 21.41.95.1-0.7-0.9-1.1-1.3-1.2-0.9-0.7-1.0-1.6-1.6-0.5-1.7-1.90.1-2.1-2.02.2
Novel to familiar place preference ratio0.10.20.70.20.40.60.20.7-0.00.10.40.50.5-0.10.30.20.80.10.1-0.4
Novelty place preference0.20.20.70.20.40.60.30.7-0.00.20.40.50.5-0.10.40.20.80.20.2-0.4
Time in novel zone, NPP test0.50.61.60.60.81.10.71.10.40.60.90.90.90.30.70.41.30.50.3-0.6
Total zone transitions, NPP test0.81.22.8-1.0-1.1-1.0-1.0-1.0-1.0-1.0-0.8-1.1-1.1-1.0-1.0-1.7-0.7-1.1-1.70.7
Total locomotion distance, NPP test1.72.45.4-1.1-1.3-1.2-1.5-1.3-1.3-1.1-1.2-1.6-1.6-1.0-1.7-2.0-0.1-2.0-2.32.1
Locomotion velocity, NPP test2.33.25.5-1.5-1.6-1.6-1.8-1.7-1.6-1.5-1.6-1.9-1.9-1.4-1.9-2.2-0.6-2.2-2.42.2
Intraocular pressure1.62.24.7-1.4-1.3-0.8-1.5-1.1-1.8-1.7-1.2-1.2-1.2-1.6-1.6-2.1-0.0-2.2-1.51.7
Delta distance traveled before/after self-admin0.30.41.8-0.6-0.5-0.7-0.6-0.5-0.4-0.1-0.9-0.6-0.6-0.0-0.7-0.3-0.2-0.51.40.5
Delta ambulatory time before/after self-admin0.20.21.2-0.5-0.4-0.5-0.6-0.3-0.4-0.1-0.7-0.5-0.50.1-0.7-0.30.2-0.41.10.2
Parametrial fat weight19.846.559.27.77.67.47.37.37.37.37.47.47.47.16.66.35.85.55.1-4.1
Pavlov. Cond. lever latency1.72.16.81.91.81.51.01.61.42.01.50.80.82.20.40.72.60.11.10.1
Pavlov. Cond. magazine entry latency0.30.41.20.20.20.10.50.10.50.20.10.50.50.10.70.9-0.81.11.0-0.9
Pavlov. Cond. change in total contacts1.71.86.2-1.8-1.6-1.4-1.0-1.5-1.4-1.8-1.6-0.6-0.6-2.2-0.3-0.3-2.50.1-0.1-0.2
Pavlov. Cond. index score0.70.95.0-1.1-1.0-1.0-0.3-1.1-0.6-1.1-0.9-0.2-0.2-1.40.20.3-2.20.8-0.0-0.7
Pavlov. Cond. latency score1.11.45.7-1.5-1.5-1.3-0.8-1.4-1.0-1.5-1.3-0.6-0.6-1.8-0.2-0.1-2.40.3-0.4-0.3
Pavlov. Cond. lever contacts0.91.15.3-1.3-1.2-1.0-0.5-1.1-0.8-1.5-0.9-0.3-0.3-1.70.1-0.0-2.30.5-0.8-0.4
Pavlov. Cond. magazine entry number0.30.41.40.10.10.0-0.40.1-0.20.10.1-0.5-0.50.4-0.7-0.81.2-1.0-0.71.0
Pavlov. Cond. intertrial magazine entries1.11.35.6-0.2-0.2-0.3-1.0-0.3-0.7-0.1-0.5-1.1-1.10.1-1.7-1.71.4-1.9-1.02.4
Pavlov. Cond. lever-magazine prob. diff.0.70.95.5-1.0-0.9-0.9-0.2-1.0-0.5-1.0-0.8-0.1-0.1-1.40.40.6-2.31.00.2-0.9
Pavlov. Cond. response bias0.40.52.9-0.5-0.4-0.30.2-0.3-0.1-0.6-0.30.40.4-1.00.80.7-1.71.10.3-1.1
Pavlov. Cond. lever latency4.05.57.1-2.6-2.6-2.6-2.6-2.6-2.4-2.4-2.5-2.7-2.7-2.2-2.6-2.2-1.8-1.9-1.61.2
Pavlov. Cond. magazine entry latency2.32.85.52.12.12.01.62.21.72.02.01.51.51.91.10.92.40.30.50.6
Pavlov. Cond. change in total contacts4.57.29.43.12.92.93.02.93.12.92.92.82.82.82.82.51.82.22.0-1.2
Pavlov. Cond. index score5.06.79.43.03.03.02.83.12.72.82.92.82.82.72.52.12.51.71.7-0.7
Pavlov. Cond. latency score4.05.37.42.62.62.62.52.72.42.52.62.52.52.32.32.02.11.61.6-0.8
Pavlov. Cond. lever contacts4.56.17.92.82.82.82.72.82.62.62.82.82.82.42.62.22.01.91.6-1.1
Pavlov. Cond. magazine entry number3.23.95.7-2.4-2.4-2.3-2.1-2.4-2.1-2.3-2.3-2.0-2.0-2.2-1.8-1.5-2.1-1.1-0.90.2
Pavlov. Cond. intertrial magazine entries0.91.42.5-1.5-1.4-1.3-1.2-1.3-1.3-1.4-1.6-1.0-1.0-1.4-1.0-0.8-1.2-0.7-0.50.6
Pavlov. Cond. lever-magazine prob. diff.5.47.29.43.13.02.92.93.12.92.93.02.92.92.82.72.32.32.01.9-1.0
Pavlov. Cond. response bias4.76.49.23.03.02.92.73.02.62.82.82.72.72.72.42.02.61.61.7-0.5
Time in closed arm before self-admin0.10.10.3-0.2-0.2-0.2-0.2-0.4-0.2-0.0-0.5-0.4-0.4-0.2-0.0-0.3-0.3-0.40.50.5
Time in closed arm after self-admin0.80.91.3-0.9-0.8-0.8-1.0-0.7-0.9-0.8-1.0-1.1-1.1-0.8-1.0-0.9-0.9-1.1-0.71.1
Time in open arm before self-admin0.10.10.30.40.2-0.00.3-0.00.50.30.40.20.20.50.10.4-0.20.40.0-0.5
Time in open arm after self-admin2.22.43.51.61.41.21.61.21.81.51.51.61.61.71.51.61.31.91.6-1.5
Bone: periosteal estimation0.91.93.51.61.61.91.51.81.41.41.71.41.41.31.30.71.60.50.20.2
Bone: periosteal perimeter0.30.51.70.90.91.00.60.90.70.90.90.40.40.80.40.21.3-0.10.00.5
Bone: post-yield work0.10.21.3-0.00.00.3-0.00.3-0.1-0.00.30.00.0-0.1-0.3-0.60.5-0.4-1.20.4
Progressive ratio test 1 active lever presses0.40.41.20.80.70.50.70.60.90.70.80.60.61.10.60.60.10.50.3-0.7
Progressive ratio test 1 breakpoint0.40.51.10.80.70.60.80.70.90.70.90.70.71.10.70.60.10.60.3-0.8
Progressive ratio test 1 inactive lever presses0.20.30.90.30.50.6-0.10.8-0.10.10.40.00.00.4-0.6-0.31.0-0.7-1.00.9
Progressive ratio test 2 active lever presses0.30.30.60.70.60.60.40.70.60.50.60.50.50.80.40.50.80.4-0.10.0
Progressive ratio test 2 breakpoint0.30.40.80.80.70.60.50.80.60.60.70.50.50.90.40.60.90.40.00.0
Progressive ratio test 2 inactive lever presses1.11.87.51.61.71.60.81.71.01.51.31.01.01.80.30.62.70.2-0.10.9
Incentive Sensitization - Responses0.30.42.90.60.60.60.20.60.30.60.40.30.30.8-0.2-0.11.7-0.2-0.11.0
Incentive Sensitization - Breakpoint0.40.63.30.90.80.70.30.80.50.80.50.40.41.0-0.10.11.8-0.00.00.9
Sum of active levers in priming session hrs 5-60.40.40.7-0.6-0.7-0.7-0.7-0.6-0.6-0.6-0.4-0.8-0.8-0.3-0.7-0.7-0.7-0.6-0.6-0.3
Progressive ratio1.21.94.6-0.9-1.0-1.0-1.4-1.2-1.2-1.1-0.8-1.5-1.5-0.7-1.8-2.1-0.0-2.2-1.81.3
Food seeking constrained by brief footshock1.21.53.1-1.3-1.6-1.7-1.2-1.7-0.9-1.2-1.2-1.3-1.3-0.9-0.9-1.2-1.6-0.6-0.7-0.3
Seeking ratio, punishment vs. effort1.01.54.20.80.70.61.20.71.21.00.81.21.20.61.71.8-0.52.01.4-1.6
Retroperitoneal fat weight19.482.9101.09.910.09.910.09.89.69.59.610.010.08.69.78.86.98.07.1-5.6
Reaction time number correct0.91.84.9-1.3-1.1-1.0-1.6-0.9-1.6-1.0-0.9-1.3-1.3-0.8-1.9-2.20.7-2.0-1.01.0
Reaction time mean minus median1.12.84.32.01.81.91.91.72.01.82.11.81.81.91.71.31.10.91.0-0.7
Reaction time mean minus median AUC1.12.74.22.01.82.01.81.91.91.72.01.71.72.01.61.31.40.70.8-0.4
Reaction time num false alarms2.53.54.9-2.0-1.9-2.2-2.1-2.1-2.0-1.9-2.2-2.1-2.1-1.9-1.8-1.5-1.6-1.5-1.11.2
Reaction time num false alarms AUC1.92.94.0-1.8-1.7-2.0-1.9-1.9-1.9-1.8-2.0-1.9-1.9-1.8-1.6-1.3-1.5-1.3-1.11.0
Reaction time trials correct on left0.91.84.9-1.3-1.1-1.0-1.6-0.9-1.6-1.0-0.9-1.3-1.3-0.8-1.9-2.20.7-2.0-1.01.0
Reaction time trials on left0.91.74.8-1.2-1.0-0.9-1.5-0.8-1.5-0.9-0.8-1.2-1.2-0.7-1.8-2.20.8-2.0-1.01.1
Reaction time mean2.94.67.42.62.42.52.52.22.52.22.72.42.42.12.21.61.61.30.7-0.9
Reaction time mean AUC2.33.65.72.32.12.22.31.92.32.02.42.12.12.02.01.51.31.10.8-0.7
Median of all reaction times2.63.76.02.32.22.32.32.02.22.02.52.22.21.82.01.51.41.20.5-0.8
Reaction time omissions0.91.32.81.31.31.41.11.31.21.31.31.21.21.50.80.21.7-0.30.50.7
Reaction time false alarm rate0.81.12.4-1.0-1.0-1.3-1.0-1.3-1.0-1.1-1.4-1.2-1.2-1.2-0.6-0.3-1.5-0.3-0.60.6
Reaction time premature initiation rate0.10.10.3-0.4-0.3-0.2-0.4-0.2-0.5-0.4-0.5-0.3-0.3-0.4-0.2-0.5-0.2-0.3-0.20.4
Reaction time premature initiations0.61.12.5-1.1-0.9-0.8-1.3-0.7-1.3-1.0-1.0-1.1-1.1-0.8-1.2-1.60.0-1.3-0.80.8
Std. dev. reaction times1.83.45.12.22.02.12.21.92.21.82.32.12.11.92.01.61.41.00.8-0.5
Reaction time trials completed0.91.74.8-1.2-1.0-0.9-1.5-0.8-1.5-0.9-0.8-1.2-1.2-0.7-1.8-2.20.8-2.0-1.01.1
Reaction time trials AUC1.01.95.2-1.2-1.0-0.8-1.6-0.7-1.6-0.9-0.8-1.3-1.3-0.8-1.9-2.30.9-2.2-1.21.3
Run reversals in cocaine runway, females3.13.14.52.12.01.82.01.72.12.02.01.81.82.01.61.81.11.41.1-0.8
Run reversals in cocaine runway, males1.91.94.11.01.11.01.51.01.41.01.11.31.30.92.02.0-0.51.91.6-1.8
Latency to leave start box in cocaine runway0.40.52.5-0.3-0.3-0.6-0.7-0.4-0.20.2-0.6-0.8-0.80.2-0.9-0.90.4-1.00.41.6
Latency to leave start box in cocaine runway, F0.10.10.80.10.20.2-0.10.30.10.40.20.00.00.3-0.0-0.20.5-0.50.10.9
Latency to leave start box in cocaine runway, M1.21.23.3-0.5-0.7-1.2-1.1-1.0-0.5-0.1-1.2-1.4-1.40.1-1.5-1.40.4-1.20.71.8
Std. dev. time between licks in bursts0.60.81.3-1.1-1.0-0.9-0.9-1.0-1.1-1.1-1.0-0.6-0.6-1.1-0.9-1.1-0.3-0.8-0.40.7
Total sessions with >9 infusions0.70.92.41.11.00.90.91.01.21.01.20.80.81.50.80.80.70.70.3-0.7
Short access day 1 total inactive lever presses0.70.93.8-0.4-0.2-0.2-0.80.1-0.6-0.3-0.3-1.0-1.00.2-1.3-1.00.9-1.3-1.42.0
Short access day 10 total inactive lever presses0.30.84.30.40.50.6-0.30.7-0.30.30.2-0.3-0.30.4-1.1-0.61.7-1.3-1.12.1
Short access day 1 total infusions0.40.51.7-0.7-0.6-0.5-0.8-0.4-0.7-0.7-0.3-0.8-0.8-0.3-0.8-0.8-0.2-0.9-1.30.6
Short access day 10 total infusions0.20.31.10.60.50.50.40.70.60.50.70.30.31.10.50.30.50.20.0-0.1
Short access total infusions0.50.61.70.90.80.90.70.90.90.91.00.60.61.30.60.70.80.50.1-0.3
Short access day 1 locomotion0.20.31.00.70.60.30.40.60.70.70.50.20.21.00.30.70.30.50.5-0.1
Short access day 10 total locomotion0.30.62.7-0.6-0.7-0.6-0.7-0.5-0.8-0.9-0.5-0.6-0.6-0.7-0.6-0.6-0.2-0.9-1.61.0
Short access total locomotion0.00.10.2-0.1-0.3-0.4-0.1-0.30.1-0.3-0.2-0.2-0.20.20.1-0.0-0.5-0.1-0.20.0
One hour access (0.3 mA shock)0.10.10.60.30.10.0-0.10.20.20.30.3-0.1-0.10.5-0.40.10.6-0.0-0.80.5
Compulsive drug intake1.92.35.7-1.3-1.6-1.5-1.4-1.7-1.4-1.7-1.3-1.4-1.4-1.7-1.4-1.5-1.4-1.3-2.41.1
One hour access (shock baseline)0.71.11.81.01.10.90.91.31.01.21.00.90.91.20.91.40.91.30.9-0.5
Social response proportion4.95.68.02.72.52.32.52.22.72.62.52.42.42.82.02.41.62.12.2-1.5
Social responses0.20.30.70.40.50.30.50.30.40.20.60.60.60.40.70.8-0.00.50.3-0.8
Social time1.21.63.31.31.31.21.31.11.41.41.21.31.31.41.31.10.70.91.8-1.1
Soleus weight0.00.10.80.10.20.30.10.30.00.10.2-0.0-0.00.00.00.10.2-0.4-0.70.9
Bone: stiffness0.10.10.50.10.30.40.20.30.10.30.10.10.10.00.3-0.40.6-0.30.30.7
Tibialis anterior weight0.62.13.51.71.71.91.61.71.41.51.71.61.61.31.41.61.31.00.6-0.4
Time to tail flick, vehicle, before self-admin1.21.22.71.61.51.20.91.21.21.51.10.70.71.70.50.51.60.50.80.2
Time to tail flick, vehicle, after self-admin0.40.51.5-0.9-0.8-0.6-0.6-0.8-0.8-1.0-0.7-0.6-0.6-1.2-0.3-0.2-1.0-0.3-0.80.3
Time to tail flick, test, before self-admin0.20.30.8-0.6-0.7-0.5-0.4-0.5-0.4-0.7-0.3-0.4-0.4-0.4-0.2-0.4-0.8-0.2-0.9-0.3
Time to tail flick, test, after self-admin0.80.93.5-0.5-0.3-0.2-0.9-0.2-1.0-0.6-0.3-0.8-0.8-0.8-1.1-1.00.5-1.5-1.91.5
Delta time to tail flick, vehicle, before/after SA1.71.74.3-1.7-1.4-1.1-1.2-1.3-1.6-1.6-1.3-0.9-0.9-2.1-0.9-0.8-1.2-1.0-1.10.7
Delta time to tail flick, test, before/after SA0.30.31.7-0.00.10.1-0.4-0.0-0.5-0.1-0.1-0.3-0.3-0.3-0.6-0.50.8-0.9-0.91.3
Tibia length1.85.17.02.42.32.32.52.42.52.22.32.52.52.32.61.81.21.92.1-1.9
Ambulatory time before self-admin0.40.62.50.50.50.70.80.50.70.60.80.80.80.41.10.7-0.21.00.7-1.6
Ambulatory time after self-admin0.20.31.8-0.5-0.4-0.4-0.2-0.4-0.2-0.1-0.4-0.1-0.1-0.0-0.0-0.0-0.40.31.3-1.2
Bone: tissue strength0.80.81.31.00.91.11.11.01.00.81.11.01.00.81.00.50.60.8-0.0-0.6
Total heroin consumption0.30.31.20.50.40.3-0.00.30.40.60.5-0.3-0.31.1-0.5-0.31.0-0.5-0.40.7
Bone: trabecular number0.10.20.8-0.6-0.6-0.4-0.3-0.4-0.3-0.5-0.6-0.4-0.4-0.5-0.2-0.1-0.5-0.4-0.20.9
Bone: trabecular spacing1.52.03.71.41.61.21.31.21.21.21.31.31.31.01.51.90.71.81.7-1.9
Bone: trabecular thickness0.20.20.6-0.5-0.6-0.4-0.3-0.4-0.3-0.5-0.5-0.3-0.3-0.5-0.2-0.7-0.6-0.4-0.40.5
Bone: trabecular tissue density0.40.61.60.70.60.40.90.50.80.50.60.80.80.31.11.0-0.11.30.8-1.1
Water consumed over 24 hours0.20.21.60.40.30.50.10.50.10.20.5-0.1-0.10.2-0.1-0.10.4-0.5-1.30.6
Number of responses in last shaping day0.80.93.8-0.8-0.7-0.5-1.0-0.4-1.1-1.0-0.5-1.0-1.0-0.8-1.1-0.7-0.3-1.0-2.00.8