Dtd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Dtd1 0.32 0.1 2.0e-14 0.33 0.35 0.34 0.35 1.1e-14 2.9e-15 5.6e-15 1.5e-15
2 Brain gene expression Dtd1 0.21 0.08 0.0e+00 0.19 0.19 0.19 0.2 8.5e-18 4.0e-17 1.6e-17 2.6e-18
3 PL gene expression Dtd1 0.16 0.07 5.6e-17 0.17 0.14 0.16 0.17 1.4e-18 4.0e-15 1.3e-17 6.2e-18
4 Liver gene expression Dtd1 0.21 0.09 2.8e-15 0.1 0.1 0.1 0.1 3.1e-11 1.6e-11 3.0e-11 4.3e-11
5 NAcc mRNA stability Dtd1 0.04 0.02 1.6e-04 0.03 0.01 0.01 -0 1.0e-05 8.3e-03 1.8e-03 5.9e-01
6 pVTA gene expression Dtd1 0.11 0.05 2.1e-11 0.11 0.13 0.12 0.11 5.8e-09 2.3e-10 8.9e-10 2.3e-09
7 Brain mRNA stability Dtd1 0.11 0.06 3.5e-09 0.08 0.07 0.09 0.09 8.0e-08 4.3e-07 2.4e-08 1.1e-08
8 Adipose gene expression Dtd1 0.33 0.12 0.0e+00 0.18 0.17 0.18 0.18 1.2e-19 6.5e-19 3.9e-19 1.1e-19
9 IL gene expression Dtd1 0.2 0.12 7.4e-03 0.09 0.01 0.05 -0 3.8e-03 1.5e-01 2.3e-02 3.7e-01
10 Liver mRNA stability Dtd1 0.06 0.05 1.2e-03 0.04 0.01 0.03 0.02 7.6e-05 6.7e-03 2.4e-04 1.2e-03
11 BLA gene expression Dtd1 0.26 0.13 3.1e-10 0.15 0.15 0.16 0.1 3.0e-08 2.7e-08 6.0e-09 7.5e-06
12 Brain intron excision ratio chr3_152449315_152453196 0.08 0.05 1.1e-04 0.05 0.02 0.03 0.04 3.4e-05 2.8e-03 1.5e-03 9.6e-05
13 IL mRNA stability Dtd1 0.24 0.12 1.7e-04 0.18 0.15 0.12 0.13 4.5e-05 2.3e-04 9.4e-04 4.3e-04
14 NAcc gene expression Dtd1 0.45 0.1 0.0e+00 0.22 0.27 0.28 0.22 7.3e-32 3.7e-40 3.4e-43 1.0e-32
15 RMTg gene expression Dtd1 0.17 0.09 4.7e-04 0.08 0.06 0.08 0.04 3.6e-03 1.1e-02 3.5e-03 2.4e-02
16 LHb mRNA stability Dtd1 0.63 0.19 1.1e-03 0.13 0.17 0.21 0.17 4.9e-04 6.1e-05 9.7e-06 6.6e-05
17 Brain intron excision ratio chr3_152453286_152466614 0.04 0.04 7.6e-03 0 0 0.01 0.01 2.4e-01 1.5e-01 7.9e-02 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.10.21.2-0.4-0.40.0-0.10.0-0.3-0.3-0.30.10.10.50.10.50.00.60.31.1
Area under the delay curve0.71.13.2-1.4-1.31.2-0.81.2-1.1-1.5-1.00.90.91.5-0.10.41.8-0.10.9-0.4
BMI with tail8.931.237.25.96.1-5.96.1-5.76.05.95.7-6.0-6.0-5.3-5.9-5.9-3.6-5.2-5.2-3.7
BMI without tail4.524.029.35.35.4-5.35.4-4.95.25.15.2-5.3-5.3-4.8-5.4-4.9-3.6-4.2-4.0-3.3
Body weight10.043.855.87.27.5-7.57.2-7.26.96.96.9-7.3-7.3-6.4-6.8-6.5-5.5-5.5-5.2-3.4
Weight adjusted by age0.10.42.0-0.6-0.40.0-0.60.0-0.8-0.3-0.70.40.40.50.50.9-1.00.9-0.21.4
Bone surface0.30.61.11.00.8-0.90.9-0.91.01.00.8-0.6-0.6-1.0-0.6-0.3-0.4-0.1-0.40.4
Bone volume0.10.21.10.30.3-0.60.3-0.60.30.30.3-0.2-0.2-0.3-0.20.4-0.50.50.11.1
Breakpoint value in progressive ratio session0.40.82.21.00.9-0.80.8-0.81.11.11.1-0.6-0.6-1.5-0.6-0.9-0.9-0.8-0.6-0.8
Number of licking bursts0.00.21.0-0.20.0-0.40.2-0.3-0.2-0.10.3-0.5-0.50.4-0.4-0.1-0.2-0.5-0.1-1.0
Context. condit. distance diff. score0.10.10.50.20.3-0.40.2-0.40.20.30.2-0.2-0.2-0.3-0.0-0.2-0.7-0.0-0.40.4
Locomotion velocity, session 11.01.12.8-0.7-1.01.2-1.11.2-0.6-0.6-0.91.31.30.21.41.70.41.10.91.0
Locomotion distance, session 14.35.47.4-2.4-2.52.5-2.52.5-2.4-2.4-2.32.42.42.22.22.72.32.12.41.1
Locomotion velocity, session 22.42.95.5-1.7-2.02.1-1.52.1-1.4-1.9-1.61.71.71.61.11.72.31.12.10.5
Locomotion distance, session 25.07.012.2-2.4-2.52.5-2.82.5-2.5-2.4-2.42.82.82.12.83.51.43.23.42.5
Locomotion velocity, session 32.93.34.4-2.1-2.11.9-2.01.9-2.0-2.0-2.01.81.81.81.82.01.41.61.11.0
Locomotion distance, session 31.01.21.9-1.4-1.41.2-1.11.1-1.2-1.3-1.21.01.01.21.00.91.20.80.70.4
Stereotopy head waving bouts, day 30.00.00.50.10.00.0-0.10.00.10.30.00.20.2-0.20.10.7-0.10.30.00.2
Stereotopy head waving duration, day 30.10.10.40.50.4-0.30.2-0.30.40.60.3-0.2-0.2-0.6-0.10.3-0.50.0-0.40.2
Locomotion velocity, session 71.41.52.2-1.4-1.31.1-1.41.2-1.5-1.4-1.31.21.21.31.31.30.81.11.10.9
Locomotion distance, session 70.20.30.7-0.6-0.40.2-0.70.3-0.8-0.7-0.40.50.50.60.60.80.10.70.50.5
Stereotopy head waving bouts, day 70.10.10.30.10.1-0.30.4-0.30.30.20.3-0.4-0.4-0.1-0.50.20.4-0.1-0.3-0.5
Stereotopy head waving duration, day 70.10.10.4-0.3-0.40.3-0.20.3-0.1-0.2-0.30.20.20.20.20.60.40.40.00.3
Locomotion velocity, session 80.81.01.7-0.7-0.91.1-1.11.1-0.7-0.7-0.81.21.20.31.31.30.51.21.11.1
Locomotion distance, session 82.33.35.4-1.7-1.71.6-2.01.7-1.9-1.7-1.71.91.91.52.02.30.82.22.01.8
Degree of sensitization distance0.30.40.80.80.9-0.90.5-0.80.40.60.8-0.6-0.6-0.5-0.4-0.1-0.9-0.0-0.10.1
Degree of sensitization stereotypy0.40.40.70.60.5-0.80.7-0.80.70.60.6-0.8-0.8-0.6-0.7-0.2-0.3-0.2-0.8-0.3
Conditioned locomotion0.20.21.20.10.0-0.0-0.3-0.0-0.10.1-0.20.30.3-0.30.70.4-1.00.80.11.1
Cocaine response after cond. corrected1.32.03.2-1.4-1.31.1-1.51.1-1.7-1.6-1.21.31.31.61.61.70.71.61.81.2
Cocaine response after cond. not corrected2.53.65.1-2.0-1.81.4-2.01.4-2.3-2.1-1.81.81.82.22.02.20.82.02.22.1
Cocaine response before conditioning0.30.31.6-0.6-0.60.5-0.40.3-0.5-0.6-0.70.60.60.60.30.30.20.30.51.3
Saline control response0.81.14.21.31.2-1.10.5-1.10.71.10.9-0.4-0.4-1.3-0.10.5-2.11.00.11.6
Bone: connectivity density0.10.20.7-0.4-0.50.5-0.30.5-0.2-0.3-0.50.50.50.40.30.20.60.50.40.8
Bone: cortical apparent density0.20.41.1-0.5-0.50.9-0.50.7-0.4-0.4-0.80.60.60.60.3-0.41.0-0.4-1.0-0.5
Bone: cortical area0.20.31.00.30.4-0.20.5-0.30.50.40.2-0.3-0.3-0.2-0.8-0.90.1-0.7-1.0-0.4
Bone: cortical porosity0.40.40.80.70.6-0.40.6-0.30.80.80.7-0.6-0.6-0.7-0.7-0.7-0.4-0.7-0.6-0.9
Bone: cortical porosity0.60.71.11.00.9-0.70.8-0.61.01.00.9-0.7-0.7-0.9-0.9-0.9-0.6-0.8-0.9-0.8
Bone: cortical thickness0.40.63.20.20.20.30.50.20.60.3-0.2-0.3-0.3-0.1-1.0-1.50.7-1.4-1.8-1.0
Bone: cortical thickness0.91.12.1-1.4-1.31.3-1.01.3-1.1-1.4-1.40.80.81.40.50.31.40.3-0.40.2
Bone: cortical tissue density0.20.30.9-0.5-0.40.8-0.50.7-0.4-0.4-0.80.50.50.50.3-0.30.9-0.2-1.0-0.4
Condit. Reinf. active minus inactive responses0.10.10.7-0.10.0-0.20.0-0.3-0.2-0.20.1-0.2-0.20.20.20.3-0.20.40.90.5
Condit. Reinf. active-inactive response ratio0.10.10.6-0.3-0.2-0.1-0.1-0.2-0.4-0.3-0.0-0.1-0.10.40.30.2-0.30.40.80.5
Condit. Reinf. active responses0.10.10.7-0.2-0.20.1-0.20.0-0.3-0.4-0.1-0.0-0.00.50.20.60.10.40.90.5
Condit. Reinf. inactive responses0.00.00.10.1-0.00.2-0.10.20.1-0.00.00.20.2-0.0-0.10.20.4-0.20.1-0.2
Incentive salience index mean0.40.51.8-0.8-0.80.6-0.40.6-0.7-1.0-0.50.20.21.10.30.51.00.31.30.3
Condit. Reinf. lever presses0.40.73.0-0.9-0.90.7-0.20.7-0.6-1.2-0.50.00.01.3-0.30.01.7-0.61.0-0.6
Condit. Reinf. active minus inactive responses1.11.73.01.61.6-1.41.2-1.41.51.61.3-1.2-1.2-1.7-0.9-1.2-1.5-0.8-0.90.3
Condit. Reinf. active-inactive response ratio0.91.52.21.51.4-1.41.2-1.41.31.41.5-1.2-1.2-1.4-0.9-1.0-1.2-0.8-0.2-0.1
Condit. Reinf. active responses0.91.33.11.31.2-0.91.1-0.91.31.30.8-1.1-1.1-1.4-1.0-1.5-0.7-1.3-1.8-0.4
Condit. Reinf. inactive responses0.30.54.00.10.10.20.30.20.40.3-0.3-0.3-0.3-0.3-0.7-0.90.5-0.9-2.0-0.8
Condit. Reinf. lever presses3.55.07.12.72.6-2.42.3-2.52.52.62.3-2.3-2.3-2.6-1.9-2.1-2.4-1.6-1.6-0.3
Condit. Reinf. lever reinforcers received1.31.82.91.51.4-1.11.3-1.21.61.61.1-1.2-1.2-1.7-1.1-1.6-1.0-1.3-1.7-0.4
Conditioned reinforcement - actives0.41.44.5-0.6-0.60.7-1.20.5-1.0-0.7-0.51.31.30.31.61.6-0.21.82.11.8
Conditioned reinforcement - inactives0.61.54.5-0.7-0.60.7-1.50.5-1.3-0.7-0.81.51.50.32.11.3-0.71.61.61.8
Conditioned locomotion0.20.31.0-0.5-0.70.8-0.60.6-0.4-0.6-0.50.70.70.20.60.20.50.31.00.5
Patch foraging indifference point 0 sec0.20.62.9-0.4-0.10.0-0.80.0-0.8-0.1-0.50.60.60.11.11.0-0.71.3-0.01.7
Patch foraging indifference point AUC0.40.91.7-1.1-1.21.3-0.91.0-0.8-1.1-1.20.90.90.80.70.51.20.30.3-0.3
Delay disc. indifference point, 0s delay0.40.51.90.30.2-0.20.7-0.30.50.00.7-0.6-0.60.0-1.1-1.00.9-1.30.2-1.4
Delay disc. indifference point, 16s delay1.21.72.8-1.6-1.61.4-1.21.4-1.4-1.6-1.31.31.31.70.61.11.70.71.10.2
Delay disc. indifference point, 2s delay0.50.51.70.20.2-0.50.8-0.40.50.00.8-0.8-0.80.0-1.3-0.70.6-1.00.3-1.3
Delay disc. indifference point, 24s delay3.35.38.4-2.9-2.72.4-2.32.4-2.7-2.9-2.42.32.32.91.41.82.51.31.80.6
Delay disc. indifference point, 4s delay0.30.31.8-0.2-0.1-0.10.40.2-0.0-0.40.2-0.5-0.50.6-1.1-0.40.9-0.8-0.2-1.3
Delay disc. indifference point, 8s delay0.71.22.1-1.4-1.41.5-1.11.4-1.1-1.3-1.21.21.21.10.60.81.30.40.70.2
Indifference point function ln k0.10.21.6-0.00.1-0.2-0.3-0.1-0.30.1-0.10.30.30.00.50.3-0.50.50.21.3
Indifference point function log k0.10.21.6-0.00.1-0.2-0.3-0.1-0.30.1-0.10.30.30.00.50.3-0.50.50.21.3
Patch foraging total patch changes 0 sec0.30.83.3-0.6-0.30.2-1.00.3-0.9-0.3-0.70.80.80.21.31.2-0.61.50.11.8
Patch foraging total patch changes 12 sec0.10.10.90.00.2-0.10.1-0.30.10.0-0.1-0.1-0.1-0.2-0.5-0.10.2-0.3-0.9-0.4
Patch foraging total patch changes 18 sec0.61.32.1-1.2-1.11.1-1.40.8-1.4-1.0-1.41.31.30.91.41.20.11.50.41.2
Patch foraging total patch changes 24 sec0.00.10.4-0.4-0.30.2-0.30.1-0.4-0.3-0.30.20.20.20.30.6-0.40.60.30.3
Patch foraging total patch changes 6 sec0.20.30.7-0.6-0.30.1-0.6-0.1-0.8-0.5-0.50.30.30.50.60.8-0.10.80.00.8
Patch foraging time to switch 0 sec0.62.43.61.51.6-1.51.8-1.41.61.41.8-1.7-1.7-1.1-1.9-1.6-0.5-1.6-0.8-1.8
Patch foraging water rate 0 sec0.82.94.0-1.9-1.81.7-1.91.8-1.9-1.7-2.01.91.91.42.01.60.91.60.81.5
Patch foraging water rate 12 sec1.25.07.2-2.5-2.52.4-2.32.4-2.5-2.7-2.72.22.22.62.01.81.81.61.61.3
Patch foraging water rate 18 sec6.314.117.6-4.0-3.93.6-3.93.7-4.2-4.2-3.63.93.93.93.73.92.73.83.82.7
Patch foraging water rate 24 sec3.55.07.2-2.4-2.21.9-2.51.9-2.7-2.5-2.12.52.52.12.62.40.92.32.11.7
Patch foraging water rate 6 sec4.36.48.1-2.8-2.72.7-2.82.7-2.8-2.8-2.92.72.72.52.52.61.52.51.41.9
Seeking ratio, delayed vs. immediate footshock0.20.30.80.80.7-0.60.5-0.40.70.80.9-0.4-0.4-0.8-0.0-0.2-0.1-0.20.0-0.7
Distance traveled before self-admin0.20.32.40.20.1-0.30.5-0.20.40.20.5-0.6-0.6-0.1-0.9-0.40.5-0.8-0.3-1.5
Distance traveled after self-admin0.20.31.2-0.6-0.60.6-0.40.6-0.2-0.2-0.60.30.30.00.20.20.6-0.2-1.1-0.9
Extensor digitorum longus weight0.10.20.60.60.6-0.70.5-0.50.50.60.6-0.3-0.3-0.7-0.3-0.4-0.80.1-0.10.4
Bone: elastic displacement0.50.62.00.70.5-0.30.7-0.20.90.60.5-0.6-0.6-0.8-0.9-0.90.6-1.0-1.1-1.4
Bone: elastic work2.63.55.51.91.8-1.72.1-1.62.11.71.9-1.9-1.9-1.7-2.3-1.8-0.3-2.0-1.9-2.0
Bone: endosteal estimation1.43.47.22.12.2-2.71.9-2.51.71.82.5-1.8-1.8-1.8-1.5-0.3-2.4-0.30.60.4
Bone: endosteal perimeter0.30.83.01.01.0-1.30.6-1.20.50.91.1-0.5-0.5-0.9-0.10.5-1.70.70.71.0
Epididymis fat weight5.829.337.06.16.1-6.15.8-6.05.85.85.9-5.8-5.8-5.4-5.3-5.0-5.1-4.6-3.8-2.5
Delta time in closed arm before/after self-admin0.20.20.4-0.4-0.40.4-0.50.1-0.5-0.5-0.40.50.50.40.60.30.20.40.70.4
Delta time in open arm before/after self-admin2.42.93.91.81.8-1.91.7-1.91.71.81.7-1.9-1.9-1.6-1.7-1.6-2.0-1.5-1.4-0.9
Diff in mean of infusions in LGA sessions0.20.42.3-0.1-0.20.10.40.10.2-0.30.1-0.4-0.40.5-0.8-0.61.3-1.0-0.1-1.5
Delay discount exponential model param1.11.43.51.61.5-1.30.9-1.41.31.61.1-1.0-1.0-1.7-0.1-0.6-1.9-0.1-1.00.3
Extinction: sum of active levers before priming0.20.21.1-0.3-0.40.5-0.50.4-0.4-0.4-0.20.60.60.10.70.40.10.41.10.1
Active lever presses in extinction session 62.22.24.61.71.6-1.31.4-1.51.81.91.5-1.0-1.0-2.1-1.2-1.5-1.2-1.3-1.6-0.9
Bone: final force0.20.41.00.50.6-0.70.7-0.70.60.40.7-0.7-0.7-0.3-1.0-0.1-0.4-0.6-0.7-0.4
Bone: final moment0.20.30.80.40.5-0.70.7-0.60.50.40.6-0.7-0.7-0.3-0.90.0-0.4-0.4-0.7-0.2
Food consumed during 24 hour testing period0.10.10.5-0.10.1-0.10.2-0.1-0.0-0.20.5-0.3-0.30.4-0.6-0.00.70.10.7-0.4
Glucose0.81.22.41.51.4-1.21.0-1.41.21.31.2-0.9-0.9-1.6-0.7-1.0-1.1-0.6-0.50.3
Heart weight1.11.83.11.51.6-1.51.4-1.41.61.71.5-1.2-1.2-1.8-1.2-0.9-1.4-0.9-1.0-0.4
Delay discount hyperbolic model param0.60.82.41.21.1-0.90.6-1.00.91.20.8-0.6-0.6-1.30.2-0.3-1.60.2-0.80.5
Intermittent access intake day 1-15 change0.21.32.01.21.2-1.41.1-1.41.21.31.4-1.2-1.2-1.2-0.6-1.3-1.3-0.9-0.1-0.2
Intermittent access intake escalation0.10.81.40.90.9-1.00.9-1.10.91.01.1-0.9-0.9-0.9-0.4-1.2-1.0-0.80.0-0.2
Intermittent access intake escalation 20.81.42.51.11.3-1.41.1-1.61.01.21.4-1.3-1.3-0.9-0.8-1.6-1.3-1.2-0.0-0.7
Intermitt. access day 1 inactive lever presses0.11.24.3-0.8-0.80.7-1.00.6-1.0-0.8-1.01.11.10.81.31.10.21.51.42.1
Intermitt. access day 15 inactive lever presses0.10.62.40.80.9-0.8-0.0-0.90.20.80.40.00.0-0.70.60.0-1.40.60.31.5
Intermitt. access escalation Index0.30.92.41.10.8-0.70.9-0.51.21.30.6-0.8-0.8-1.3-0.7-0.5-1.4-0.6-1.60.3
Intermittent access day 1 total infusions0.00.10.20.1-0.00.20.0-0.10.20.0-0.20.10.1-0.5-0.4-0.10.0-0.1-0.40.3
Intermittent access day 15 total infusions0.30.71.50.90.9-0.80.8-1.01.01.00.7-0.7-0.7-1.2-0.8-1.1-0.8-0.8-0.70.1
Intermittent access terminal intake (last 3 days)0.71.22.01.11.1-1.01.1-1.21.21.20.9-1.0-1.0-1.4-1.2-1.3-1.0-1.3-0.9-0.5
Intermittent access total infusions0.70.82.21.11.0-0.80.8-1.11.11.10.9-0.7-0.7-1.5-0.7-0.8-1.0-0.7-0.6-0.1
Intermittent access day 1 locomotion0.20.31.0-0.5-0.71.0-0.40.8-0.3-0.7-0.80.60.60.3-0.10.30.90.10.20.3
Intermittent access day 15 total locomotion0.20.71.21.10.9-0.70.8-1.11.00.90.7-0.7-0.7-1.0-0.7-1.1-1.1-0.7-0.10.2
Intermittent access total locomotion0.00.00.10.1-0.10.30.00.00.2-0.1-0.10.00.0-0.3-0.2-0.30.0-0.30.30.1
Intermittent access standard deviation0.00.10.5-0.1-0.00.0-0.1-0.20.00.10.30.00.0-0.30.3-0.3-0.1-0.30.7-0.2
Left kidney weight0.75.58.12.82.7-2.52.7-2.42.82.72.5-2.4-2.4-2.7-2.2-2.1-2.1-1.6-1.5-0.7
Right kidney weight0.21.72.91.71.6-1.51.5-1.21.61.71.6-1.3-1.3-1.6-0.9-0.9-1.5-0.5-0.20.1
Cocaine induced anxiety0.10.31.0-0.2-0.40.5-0.50.5-0.2-0.1-0.60.70.7-0.00.80.7-0.10.7-0.11.0
Post-drug Anxiety0.40.51.00.80.8-0.80.6-1.00.70.70.5-0.6-0.6-0.7-0.4-0.7-0.7-0.7-0.9-0.3
Baseline Anxiety2.03.35.71.61.8-2.01.9-2.21.51.41.8-2.0-2.0-1.2-1.9-2.4-0.9-2.2-1.2-2.1
Tail length0.31.72.71.41.6-1.61.3-1.51.21.31.4-1.5-1.5-1.3-1.4-0.9-1.6-0.7-0.6-0.5
Length with tail1.87.912.03.23.3-3.53.0-3.42.73.03.0-3.1-3.1-2.9-2.5-2.0-3.4-1.6-1.4-0.6
Length without tail1.05.49.72.62.7-2.72.5-3.12.32.62.3-2.5-2.5-2.3-1.9-2.0-2.6-1.5-1.60.0
Times rat made contact with spout3.23.75.32.32.1-2.12.1-2.12.22.12.3-1.9-1.9-2.1-1.9-1.9-1.2-1.6-0.6-0.9
Lifetime Intake0.50.71.80.90.8-0.80.7-1.01.01.00.9-0.7-0.7-1.3-0.6-0.7-0.9-0.6-0.4-0.1
Liver weight, left1.52.65.11.71.9-2.21.6-2.11.51.81.7-1.8-1.8-1.6-1.3-0.9-2.3-0.6-1.30.0
Liver weight, right1.62.74.42.02.1-2.11.8-1.91.61.81.9-1.8-1.8-1.6-1.3-1.7-1.6-0.9-0.8-0.4
Locomotor activity0.10.20.40.60.5-0.40.5-0.60.60.50.5-0.3-0.3-0.6-0.6-0.6-0.2-0.4-0.0-0.5
Locomotor testing distance0.00.10.2-0.1-0.10.4-0.20.2-0.0-0.1-0.10.30.30.0-0.1-0.20.3-0.20.5-0.2
Locomotor testing rearing0.10.40.70.70.7-0.50.5-0.60.70.70.8-0.4-0.4-0.8-0.4-0.7-0.6-0.60.3-0.5
Locomotion in novel chamber1.21.64.7-0.9-0.91.0-1.40.8-1.1-0.7-1.31.31.30.42.11.7-0.41.80.72.2
Locomotion in novel chamber post-restriction0.82.44.7-1.5-1.41.5-1.71.3-1.6-1.3-1.71.61.61.11.72.20.32.01.11.7
Fecal boli incidents, locomotor time 10.71.73.8-1.2-1.11.0-1.41.2-1.4-1.3-0.91.21.21.11.21.9-0.41.81.81.3
Change in fecal boli incidents, locomotor task0.10.10.70.20.00.0-0.00.20.30.4-0.20.20.2-0.40.30.10.20.1-0.80.7
Time >=10cm from walls, locomotor time 10.30.41.1-0.6-0.60.4-0.50.4-0.5-0.5-0.60.60.60.50.70.70.71.00.41.0
Bouts of movement, locomotor time 12.12.87.5-1.7-1.61.4-1.61.6-1.9-1.9-1.21.41.42.01.21.91.21.72.70.6
Total resting periods, locomotor time 13.13.69.2-1.9-1.91.5-1.91.9-2.1-2.2-1.51.71.72.21.62.21.22.03.00.8
Rest time, locomotor task time 10.71.27.0-0.8-0.80.3-0.90.6-1.2-1.2-0.30.60.61.21.01.4-0.01.42.60.6
Distance moved, locomotor task time 10.30.94.7-1.0-1.01.3-0.61.2-0.4-0.7-1.11.01.00.80.1-0.02.2-0.3-0.7-0.5
Vertical activity count, locomotor time 10.10.41.10.60.6-0.40.9-0.30.80.70.5-0.7-0.7-0.5-1.0-0.80.3-0.6-0.8-0.2
Time >=10cm from walls, locomotor time 20.41.32.41.31.2-1.41.2-1.51.31.21.3-1.1-1.1-1.2-1.0-1.2-1.0-0.8-0.4-0.2
Bouts of movement, locomotor time 20.10.21.20.40.30.00.3-0.30.50.50.4-0.1-0.1-0.6-0.5-0.20.2-0.6-0.1-1.1
Total resting periods, locomotor time 20.10.20.90.50.4-0.10.4-0.40.60.70.5-0.2-0.2-0.7-0.4-0.2-0.0-0.6-0.2-1.0
Rest time, locomotor task time 20.10.10.3-0.4-0.30.1-0.40.2-0.5-0.3-0.00.30.30.50.50.60.40.40.4-0.4
Distance moved, locomotor task time 20.60.82.2-0.9-1.01.2-0.71.0-0.8-1.1-1.00.90.91.10.50.11.50.11.1-0.1
Vertical activity count, locomotor time 20.00.10.30.10.00.10.20.00.2-0.10.0-0.1-0.10.0-0.2-0.50.4-0.20.50.1
Light reinforcement 10.10.31.7-0.10.00.0-0.40.0-0.5-0.2-0.00.30.30.20.51.1-0.61.01.30.8
Light reinforcement 20.30.62.80.50.3-0.0-0.40.20.00.60.10.50.5-0.91.11.3-1.71.20.31.0
Bone: marrow area1.43.37.02.12.2-2.71.9-2.51.71.82.4-1.8-1.8-1.8-1.4-0.3-2.4-0.30.60.5
Bone: maximum diameter0.51.02.11.11.3-1.51.0-1.40.81.01.2-1.0-1.0-0.8-0.9-0.8-1.4-0.2-0.30.3
Bone: maximum force0.10.20.80.40.5-0.70.6-0.60.40.40.5-0.6-0.6-0.2-0.90.1-0.3-0.2-0.30.0
Bone: maximum moment0.10.20.70.30.4-0.70.6-0.60.40.30.5-0.6-0.6-0.1-0.90.2-0.2-0.2-0.40.0
Mean time between licks in bursts0.10.41.9-0.5-0.50.5-0.50.6-0.5-0.4-0.70.40.40.40.71.4-0.11.1-0.60.9
Mean num. licks in bursts0.30.81.71.31.1-0.70.9-0.91.31.10.9-0.5-0.5-1.3-0.7-1.0-0.3-0.3-0.10.6
Cd content in liver0.20.20.8-0.4-0.1-0.40.0-0.4-0.6-0.70.2-0.4-0.40.9-0.20.3-0.10.20.9-0.1
Co content in liver0.50.60.9-0.8-0.80.8-0.90.7-0.8-0.8-0.90.80.80.60.80.60.30.70.70.9
Cu content in liver0.70.91.4-1.1-1.01.0-1.00.9-1.1-1.2-0.91.01.01.10.60.71.20.50.80.0
Fe content in liver1.11.42.41.21.2-0.91.3-1.11.31.21.4-1.0-1.0-1.0-1.4-1.5-0.3-1.5-0.6-1.5
K content in liver1.51.54.1-1.4-1.51.6-1.11.7-1.0-1.4-1.51.11.11.30.60.42.0-0.1-0.2-0.7
Mg content in liver0.10.11.10.10.10.10.00.20.10.2-0.20.00.0-0.20.0-0.40.2-0.3-1.1-0.5
Mn content in liver1.11.24.1-0.5-0.70.7-1.10.8-0.6-0.3-1.11.21.2-0.21.61.6-0.61.6-0.52.0
Na content in liver0.50.62.70.50.30.10.60.01.00.70.3-0.2-0.2-0.7-0.7-1.60.7-1.4-0.9-1.1
Rb content in liver0.10.10.4-0.10.2-0.30.3-0.3-0.0-0.00.1-0.3-0.30.4-0.6-0.30.5-0.4-0.3-0.6
Se content in liver0.30.31.00.10.1-0.10.50.10.3-0.10.2-0.5-0.50.1-0.9-0.80.9-1.0-0.7-0.9
Sr content in liver0.80.71.5-0.8-0.80.6-0.90.8-0.8-0.6-0.80.90.90.60.91.2-0.11.20.61.2
Zn content in liver0.50.51.3-0.8-0.81.0-0.51.1-0.6-0.9-0.60.60.61.00.2-0.11.20.00.9-0.4
Bone: minimum diameter0.40.81.21.11.0-1.01.0-0.91.11.00.9-0.8-0.8-1.0-0.9-0.8-0.8-0.5-0.80.1
Time in familiar zone, hab. session 10.20.30.70.20.2-0.20.6-0.20.3-0.00.3-0.7-0.70.3-0.8-0.50.9-0.80.3-0.6
Time in novel zone, hab. session 10.30.32.20.50.5-0.50.2-0.60.40.70.5-0.2-0.2-0.90.2-0.3-1.50.3-0.40.3
Total zone transitions, hab. session 11.11.53.5-1.2-1.31.3-1.31.4-1.2-1.2-1.01.21.21.21.11.81.20.91.90.1
Total locomotion distance, hab. session 11.92.85.3-1.6-1.61.9-1.72.0-1.6-1.6-1.51.91.91.61.51.61.71.22.30.4
Locomotion velocity, hab. session 12.43.44.7-1.8-1.92.1-1.92.2-1.8-1.8-1.82.02.01.91.71.91.91.52.10.6
Time in familiar zone, hab. session 20.10.20.90.1-0.10.3-0.30.4-0.00.0-0.20.40.4-0.10.60.3-0.10.50.90.7
Time in novel zone, hab. session 20.60.61.30.70.7-1.00.8-1.10.60.70.8-0.9-0.9-0.7-0.9-0.6-0.8-0.7-0.8-0.6
Total zone transitions, hab. session 20.30.31.50.0-0.1-0.0-0.20.1-0.10.00.10.30.3-0.00.51.2-0.61.01.21.0
Total locomotion distance, hab. session 21.01.34.7-0.3-0.50.6-0.90.7-0.5-0.3-0.51.21.20.11.41.6-0.61.91.92.2
Locomotion velocity, hab. session 21.51.95.1-0.7-0.91.1-1.31.2-0.9-0.7-1.01.61.60.51.71.9-0.12.12.02.2
Novel to familiar place preference ratio0.10.20.70.20.4-0.60.2-0.7-0.00.10.4-0.5-0.50.1-0.3-0.2-0.8-0.1-0.1-0.4
Novelty place preference0.10.20.70.20.4-0.60.3-0.7-0.00.20.4-0.5-0.50.1-0.4-0.2-0.8-0.2-0.3-0.4
Time in novel zone, NPP test0.50.61.60.60.8-1.10.7-1.10.40.60.9-0.9-0.9-0.3-0.7-0.4-1.2-0.5-0.3-0.6
Total zone transitions, NPP test0.81.22.9-1.0-1.11.0-1.01.0-1.0-1.0-0.81.11.11.01.01.70.71.11.70.7
Total locomotion distance, NPP test1.72.45.5-1.1-1.31.2-1.51.3-1.3-1.1-1.21.61.61.01.72.00.12.02.32.1
Locomotion velocity, NPP test2.23.25.6-1.5-1.61.6-1.81.7-1.6-1.5-1.61.91.91.41.92.20.62.22.42.2
Intraocular pressure1.42.24.7-1.4-1.30.8-1.51.1-1.8-1.7-1.21.21.21.61.62.10.02.21.51.7
Delta distance traveled before/after self-admin0.30.42.0-0.6-0.50.7-0.60.5-0.4-0.1-0.90.60.60.00.70.30.20.5-1.40.5
Delta ambulatory time before/after self-admin0.10.31.4-0.5-0.40.5-0.60.3-0.4-0.1-0.70.50.5-0.10.70.3-0.20.4-1.20.2
Parametrial fat weight19.746.459.37.77.6-7.47.3-7.37.37.37.4-7.4-7.4-7.1-6.6-6.3-5.8-5.5-5.0-4.1
Pavlov. Cond. lever latency1.72.16.81.91.8-1.51.0-1.61.42.01.5-0.8-0.8-2.2-0.4-0.7-2.6-0.1-1.00.1
Pavlov. Cond. magazine entry latency0.30.41.20.20.2-0.10.5-0.10.50.20.1-0.5-0.5-0.1-0.7-0.90.8-1.1-1.0-0.9
Pavlov. Cond. change in total contacts1.71.86.2-1.8-1.61.4-1.01.5-1.4-1.8-1.60.60.62.20.30.32.5-0.10.1-0.2
Pavlov. Cond. index score0.70.95.0-1.1-1.01.0-0.31.1-0.6-1.1-0.90.20.21.4-0.2-0.32.2-0.8-0.0-0.7
Pavlov. Cond. latency score1.11.45.7-1.5-1.51.3-0.81.4-1.0-1.5-1.30.60.61.80.20.12.4-0.30.4-0.3
Pavlov. Cond. lever contacts0.91.15.3-1.3-1.21.0-0.51.1-0.8-1.5-0.90.30.31.7-0.10.02.3-0.50.8-0.4
Pavlov. Cond. magazine entry number0.30.41.40.10.1-0.0-0.4-0.1-0.20.10.10.50.5-0.40.70.8-1.21.00.81.0
Pavlov. Cond. intertrial magazine entries1.11.35.6-0.2-0.20.3-1.00.3-0.7-0.1-0.51.11.1-0.11.71.7-1.41.91.02.4
Pavlov. Cond. lever-magazine prob. diff.0.70.95.5-1.0-0.90.9-0.21.0-0.5-1.0-0.80.10.11.4-0.4-0.62.4-1.0-0.2-0.9
Pavlov. Cond. response bias0.40.52.9-0.5-0.40.30.20.3-0.1-0.6-0.3-0.4-0.41.0-0.8-0.71.7-1.1-0.4-1.1
Pavlov. Cond. lever latency3.95.57.1-2.6-2.62.6-2.62.6-2.4-2.4-2.52.72.72.22.62.21.81.91.61.2
Pavlov. Cond. magazine entry latency2.02.85.62.12.1-2.01.6-2.21.72.02.0-1.5-1.5-1.9-1.1-0.9-2.4-0.3-0.50.6
Pavlov. Cond. change in total contacts2.97.29.43.12.9-2.93.0-2.93.12.92.9-2.8-2.8-2.8-2.8-2.5-1.8-2.2-2.0-1.2
Pavlov. Cond. index score4.36.79.43.03.0-3.02.8-3.12.72.82.9-2.8-2.8-2.7-2.5-2.1-2.5-1.7-1.6-0.8
Pavlov. Cond. latency score3.35.37.42.62.6-2.62.5-2.72.42.52.6-2.5-2.5-2.3-2.3-2.0-2.1-1.6-1.5-0.8
Pavlov. Cond. lever contacts4.26.17.92.82.8-2.82.7-2.82.62.62.8-2.8-2.8-2.4-2.6-2.2-2.1-1.9-1.6-1.1
Pavlov. Cond. magazine entry number3.03.95.7-2.4-2.42.3-2.12.4-2.1-2.3-2.32.02.02.21.81.52.11.10.90.2
Pavlov. Cond. intertrial magazine entries0.61.42.5-1.5-1.41.3-1.21.3-1.3-1.4-1.61.01.01.41.00.81.20.70.40.6
Pavlov. Cond. lever-magazine prob. diff.4.77.29.43.13.0-2.92.9-3.12.92.93.0-2.9-2.9-2.8-2.7-2.3-2.3-2.0-1.8-1.0
Pavlov. Cond. response bias4.66.49.23.03.0-2.92.7-3.02.62.82.8-2.7-2.7-2.7-2.4-2.0-2.6-1.6-1.6-0.5
Time in closed arm before self-admin0.10.10.3-0.2-0.20.2-0.20.4-0.2-0.0-0.50.40.40.20.00.30.30.4-0.40.5
Time in closed arm after self-admin0.80.91.3-0.9-0.80.8-1.00.7-0.9-0.8-1.01.11.10.81.00.90.91.10.71.1
Time in open arm before self-admin0.10.10.30.40.20.00.30.00.50.30.4-0.2-0.2-0.5-0.1-0.40.2-0.4-0.0-0.5
Time in open arm after self-admin2.22.43.51.61.4-1.21.6-1.21.81.51.5-1.6-1.6-1.7-1.5-1.6-1.3-1.9-1.5-1.5
Bone: periosteal estimation0.81.93.51.61.6-1.91.5-1.81.41.41.7-1.4-1.4-1.3-1.3-0.7-1.6-0.5-0.20.2
Bone: periosteal perimeter0.30.51.70.90.9-1.00.6-0.90.70.90.9-0.4-0.4-0.8-0.4-0.2-1.30.1-0.00.5
Bone: post-yield work0.10.21.3-0.00.0-0.3-0.0-0.3-0.1-0.00.3-0.0-0.00.10.30.6-0.50.41.20.4
Progressive ratio test 1 active lever presses0.30.41.20.80.7-0.50.7-0.60.90.70.8-0.6-0.6-1.1-0.6-0.6-0.1-0.5-0.2-0.7
Progressive ratio test 1 breakpoint0.30.51.10.80.7-0.60.8-0.70.90.70.9-0.7-0.7-1.1-0.7-0.6-0.1-0.6-0.3-0.8
Progressive ratio test 1 inactive lever presses0.10.31.00.30.5-0.6-0.1-0.8-0.10.10.4-0.0-0.0-0.40.60.3-1.00.70.90.9
Progressive ratio test 2 active lever presses0.20.30.60.70.6-0.60.4-0.70.60.50.6-0.5-0.5-0.8-0.4-0.5-0.8-0.40.10.0
Progressive ratio test 2 breakpoint0.30.40.80.80.7-0.60.5-0.80.60.60.7-0.5-0.5-0.9-0.4-0.6-0.9-0.4-0.00.0
Progressive ratio test 2 inactive lever presses0.61.87.51.61.7-1.60.8-1.71.01.51.3-1.0-1.0-1.8-0.3-0.6-2.7-0.20.10.9
Incentive Sensitization - Responses0.10.42.90.60.6-0.60.2-0.60.30.60.4-0.3-0.3-0.80.20.1-1.70.20.11.0
Incentive Sensitization - Breakpoint0.20.63.30.90.8-0.70.3-0.80.50.80.5-0.4-0.4-1.00.1-0.1-1.80.0-0.00.9
Sum of active levers in priming session hrs 5-60.40.40.7-0.6-0.70.7-0.70.6-0.6-0.6-0.40.80.80.30.70.70.70.60.7-0.3
Progressive ratio0.61.94.6-0.9-1.01.0-1.41.2-1.2-1.1-0.81.51.50.71.82.10.02.21.81.3
Food seeking constrained by brief footshock1.21.53.1-1.3-1.61.7-1.21.7-0.9-1.2-1.21.31.30.90.91.21.60.60.7-0.3
Seeking ratio, punishment vs. effort0.71.54.20.80.7-0.61.2-0.71.21.00.8-1.2-1.2-0.6-1.7-1.80.5-2.0-1.4-1.6
Retroperitoneal fat weight18.582.9101.09.910.1-9.910.0-9.89.69.59.6-10.0-10.0-8.6-9.7-8.8-7.0-8.0-7.0-5.6
Reaction time number correct0.51.84.9-1.3-1.11.0-1.60.9-1.6-1.0-0.91.31.30.81.92.2-0.72.01.01.0
Reaction time mean minus median0.42.84.32.01.8-1.91.9-1.72.01.82.1-1.8-1.8-1.9-1.7-1.3-1.1-0.9-1.0-0.7
Reaction time mean minus median AUC0.42.74.22.01.8-2.01.8-1.91.91.72.0-1.7-1.7-2.0-1.6-1.3-1.5-0.7-0.8-0.4
Reaction time num false alarms2.13.54.9-2.0-1.92.2-2.12.1-2.0-1.9-2.22.12.11.91.81.51.61.51.11.2
Reaction time num false alarms AUC1.32.94.0-1.8-1.72.0-1.91.9-1.9-1.8-2.01.91.91.81.61.31.51.31.11.0
Reaction time trials correct on left0.51.84.9-1.3-1.11.0-1.60.9-1.6-1.0-0.91.31.30.81.92.2-0.72.01.01.0
Reaction time trials on left0.51.74.8-1.2-1.00.9-1.50.8-1.5-0.9-0.81.21.20.71.82.2-0.82.00.91.1
Reaction time mean2.14.67.42.62.4-2.52.5-2.22.52.22.7-2.4-2.4-2.1-2.2-1.6-1.6-1.3-0.7-0.9
Reaction time mean AUC1.53.65.72.32.1-2.22.3-1.92.32.02.4-2.1-2.1-2.0-2.0-1.5-1.3-1.1-0.7-0.7
Median of all reaction times2.33.76.02.32.2-2.32.3-2.02.22.02.5-2.2-2.2-1.8-2.0-1.5-1.4-1.2-0.5-0.8
Reaction time omissions0.81.32.91.31.3-1.41.1-1.31.21.31.3-1.2-1.2-1.5-0.8-0.2-1.70.3-0.50.7
Reaction time false alarm rate0.81.12.4-1.0-1.01.3-1.01.3-1.0-1.1-1.41.21.21.20.60.31.50.30.60.6
Reaction time premature initiation rate0.10.10.3-0.4-0.30.2-0.40.2-0.5-0.4-0.50.30.30.40.20.50.20.30.20.4
Reaction time premature initiations0.41.12.5-1.1-0.90.8-1.30.7-1.3-1.0-1.01.11.10.81.21.6-0.01.30.80.8
Std. dev. reaction times1.03.45.12.22.0-2.12.2-1.92.21.82.3-2.1-2.1-1.9-2.0-1.6-1.5-1.0-0.8-0.5
Reaction time trials completed0.51.74.8-1.2-1.00.9-1.50.8-1.5-0.9-0.81.21.20.71.82.2-0.82.00.91.1
Reaction time trials AUC0.51.95.2-1.2-1.00.8-1.60.7-1.6-0.9-0.81.31.30.81.92.3-0.92.21.11.3
Run reversals in cocaine runway, females2.73.14.52.12.0-1.82.0-1.72.12.02.0-1.8-1.8-2.0-1.6-1.8-1.2-1.4-1.1-0.8
Run reversals in cocaine runway, males1.71.94.11.01.1-1.01.5-1.01.41.01.1-1.3-1.3-0.9-2.0-2.00.5-1.9-1.6-1.8
Latency to leave start box in cocaine runway0.30.52.5-0.3-0.30.6-0.70.4-0.20.2-0.60.80.8-0.20.90.9-0.41.0-0.41.6
Latency to leave start box in cocaine runway, F0.10.10.80.10.2-0.2-0.1-0.30.10.40.2-0.0-0.0-0.30.00.2-0.50.5-0.10.9
Latency to leave start box in cocaine runway, M1.21.23.3-0.5-0.71.2-1.11.0-0.5-0.1-1.21.41.4-0.11.51.4-0.41.2-0.71.8
Std. dev. time between licks in bursts0.40.81.3-1.1-1.00.9-0.91.0-1.1-1.1-1.00.60.61.10.91.10.30.80.30.7
Total sessions with >9 infusions0.70.92.41.11.0-0.90.9-1.01.21.01.2-0.8-0.8-1.5-0.8-0.8-0.7-0.7-0.3-0.7
Short access day 1 total inactive lever presses0.40.93.8-0.4-0.20.2-0.8-0.1-0.6-0.3-0.31.01.0-0.21.31.0-0.91.31.41.9
Short access day 10 total inactive lever presses0.10.84.30.40.5-0.6-0.3-0.7-0.30.30.20.30.3-0.41.10.6-1.71.31.12.1
Short access day 1 total infusions0.30.51.7-0.7-0.60.5-0.80.4-0.7-0.7-0.30.80.80.30.80.80.20.91.30.6
Short access day 10 total infusions0.20.31.10.60.5-0.50.4-0.70.60.50.7-0.3-0.3-1.1-0.5-0.3-0.6-0.2-0.0-0.1
Short access total infusions0.40.61.70.90.8-0.90.7-0.90.90.81.0-0.6-0.6-1.3-0.6-0.7-0.8-0.5-0.0-0.3
Short access day 1 locomotion0.20.31.00.70.6-0.30.4-0.60.70.70.5-0.2-0.2-1.0-0.3-0.7-0.3-0.5-0.5-0.1
Short access day 10 total locomotion0.10.62.6-0.6-0.70.6-0.70.5-0.8-0.9-0.50.60.60.70.60.60.20.91.61.0
Short access total locomotion0.00.10.2-0.1-0.30.4-0.10.30.1-0.3-0.20.20.2-0.2-0.10.00.50.10.20.0
One hour access (0.3 mA shock)0.10.10.70.30.1-0.0-0.1-0.20.20.30.30.10.1-0.50.4-0.1-0.60.00.80.5
Compulsive drug intake1.62.35.9-1.3-1.61.5-1.41.7-1.4-1.7-1.31.41.41.71.41.51.41.32.41.1
One hour access (shock baseline)0.41.11.81.01.1-0.90.9-1.31.01.21.0-0.9-0.9-1.2-0.9-1.4-0.9-1.3-0.9-0.5
Social response proportion4.45.58.02.72.5-2.32.5-2.22.72.62.5-2.4-2.4-2.8-2.0-2.4-1.6-2.1-2.2-1.5
Social responses0.20.30.70.40.5-0.30.5-0.30.40.20.6-0.6-0.6-0.4-0.7-0.80.0-0.5-0.4-0.8
Social time1.01.63.31.31.3-1.21.3-1.11.41.41.2-1.3-1.3-1.4-1.3-1.1-0.7-0.9-1.8-1.1
Soleus weight0.00.10.80.10.2-0.30.1-0.30.00.10.20.00.0-0.0-0.0-0.1-0.30.40.70.9
Bone: stiffness0.10.10.50.10.3-0.40.2-0.30.10.30.1-0.1-0.1-0.0-0.30.4-0.60.3-0.30.7
Tibialis anterior weight0.62.13.51.71.7-1.91.6-1.71.41.51.7-1.6-1.6-1.3-1.4-1.6-1.3-1.0-0.6-0.4
Time to tail flick, vehicle, before self-admin1.01.22.71.61.5-1.20.9-1.21.21.51.1-0.7-0.7-1.7-0.5-0.5-1.6-0.5-0.80.2
Time to tail flick, vehicle, after self-admin0.30.51.5-0.9-0.80.6-0.60.8-0.8-1.0-0.70.60.61.20.30.21.00.30.80.3
Time to tail flick, test, before self-admin0.20.30.8-0.6-0.70.5-0.40.5-0.4-0.7-0.30.40.40.40.20.40.80.20.9-0.3
Time to tail flick, test, after self-admin0.80.93.6-0.5-0.30.2-0.90.2-1.0-0.6-0.30.80.80.81.11.0-0.51.51.91.5
Delta time to tail flick, vehicle, before/after SA1.51.74.3-1.7-1.41.1-1.21.3-1.6-1.6-1.30.90.92.10.90.81.21.01.10.7
Delta time to tail flick, test, before/after SA0.20.31.7-0.00.1-0.1-0.40.0-0.5-0.1-0.10.30.30.30.60.5-0.80.90.81.3
Tibia length1.85.17.02.42.3-2.32.5-2.42.52.22.3-2.5-2.5-2.3-2.6-1.8-1.2-1.9-2.1-1.9
Ambulatory time before self-admin0.20.62.50.50.5-0.70.8-0.50.70.60.8-0.8-0.8-0.4-1.1-0.70.2-1.0-0.7-1.6
Ambulatory time after self-admin0.20.31.9-0.5-0.40.4-0.20.4-0.2-0.1-0.40.10.10.00.00.00.5-0.3-1.4-1.2
Bone: tissue strength0.80.81.31.00.9-1.11.1-1.01.00.81.1-1.0-1.0-0.8-1.0-0.5-0.6-0.80.1-0.6
Total heroin consumption0.30.31.20.50.4-0.3-0.0-0.30.40.60.50.30.3-1.10.50.3-1.00.50.40.7
Bone: trabecular number0.10.20.8-0.6-0.60.4-0.30.4-0.3-0.5-0.60.40.40.50.20.10.50.40.20.9
Bone: trabecular spacing1.42.03.71.41.6-1.21.3-1.21.21.21.3-1.3-1.3-1.0-1.5-1.9-0.7-1.8-1.7-1.9
Bone: trabecular thickness0.20.20.6-0.5-0.60.4-0.30.4-0.3-0.5-0.50.30.30.50.20.70.60.40.40.5
Bone: trabecular tissue density0.30.61.60.70.6-0.40.9-0.50.80.50.6-0.8-0.8-0.3-1.1-1.00.1-1.3-0.8-1.1
Water consumed over 24 hours0.10.21.70.40.3-0.50.1-0.50.10.20.50.10.1-0.20.10.1-0.40.51.30.6
Number of responses in last shaping day0.70.93.8-0.8-0.70.5-1.00.4-1.1-1.0-0.51.01.00.81.10.70.31.02.00.8