Hub : Genes

LOC100362820

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC100362820 0.27 0.16 3.3e-05 0.08 0.14 0.13 0.13 5.7e-03 3.9e-04 5.7e-04 6.5e-04
2 BLA gene expression LOC100362820 0.26 0.13 0.0e+00 0.3 0.32 0.32 0.33 1.5e-16 3.1e-17 1.5e-17 3.4e-18
3 LHb gene expression LOC100362820 0.23 0.13 5.3e-05 0.13 0.14 0.13 0.07 5.7e-04 3.0e-04 6.1e-04 9.2e-03
4 PL gene expression LOC100362820 0.14 0.07 0.0e+00 0.2 0.21 0.2 0.21 2.2e-21 1.2e-22 1.1e-21 2.9e-22
5 IL gene expression LOC100362820 0.11 0.09 7.9e-03 0.04 0.08 0.04 0.07 5.1e-02 6.8e-03 3.9e-02 8.9e-03
6 Brain gene expression LOC100362820 0.25 0.1 0.0e+00 0.38 0.38 0.38 0.38 7.9e-38 1.9e-37 4.6e-37 1.5e-37
7 NAcc gene expression LOC100362820 0.07 0.04 5.6e-17 0.12 0.12 0.12 0.12 7.9e-18 1.7e-17 2.4e-17 2.1e-17
8 IC gene expression LOC100362820 0.22 0.13 4.9e-10 0.22 0.21 0.22 0.21 1.5e-09 3.3e-09 1.9e-09 2.1e-09
9 pVTA gene expression LOC100362820 0.1 0.07 9.7e-10 0.12 0.12 0.12 0.12 4.7e-10 3.6e-10 1.4e-09 8.5e-10
10 Adipose gene expression LOC100362820 0.06 0.04 5.0e-07 0.04 0.04 0.04 0.04 1.6e-05 1.8e-05 7.0e-05 9.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density6.511.113.5-3.7-3.3-3.5-3.5-3.4-3.0-3.2-3.2-3.1-3.3
Area under the delay curve1.11.32.6-1.0-1.1-1.1-1.1-1.1-1.1-1.1-1.0-1.1-1.6
BMI with tail6.321.626.4-4.8-5.1-4.8-4.7-4.7-4.5-4.5-4.7-4.5-4.1
BMI without tail1.75.26.7-2.5-2.6-2.4-2.3-2.3-2.3-2.1-2.2-2.2-1.8
Body weight6.829.834.5-5.9-5.9-5.7-5.5-5.5-5.4-5.3-5.3-5.3-4.7
Weight adjusted by age0.40.71.1-0.6-1.1-0.8-0.9-0.8-0.6-0.8-1.0-0.7-0.6
Bone surface8.715.818.7-4.3-4.0-4.2-4.1-4.0-3.7-3.9-3.7-3.8-3.8
Bone volume8.014.416.6-4.1-3.7-4.0-3.9-3.9-3.7-3.8-3.6-3.7-3.8
Breakpoint value in progressive ratio session0.60.71.0-1.0-1.0-0.9-0.9-0.8-1.0-0.7-1.0-0.7-0.5
Number of licking bursts0.81.31.71.31.21.11.11.10.81.01.31.11.3
Context. condit. distance diff. score0.30.40.8-0.8-0.6-0.7-0.6-0.6-0.9-0.6-0.5-0.5-0.4
Locomotion velocity, session 14.24.55.82.11.92.12.12.12.42.22.12.22.1
Locomotion distance, session 13.24.04.82.12.02.02.02.02.21.91.91.91.9
Locomotion velocity, session 20.40.51.20.60.60.70.60.61.10.70.60.70.6
Locomotion distance, session 23.44.76.22.32.12.22.12.12.52.12.02.12.0
Locomotion velocity, session 34.95.66.12.32.52.42.42.42.42.32.42.32.3
Locomotion distance, session 32.83.14.01.52.01.81.91.81.81.71.71.71.7
Stereotopy head waving bouts, day 30.00.00.10.3-0.2-0.0-0.1-0.10.00.0-0.2-0.0-0.1
Stereotopy head waving duration, day 30.00.00.10.3-0.00.20.10.20.30.30.00.30.1
Locomotion velocity, session 72.72.93.51.41.71.61.71.71.81.91.61.91.8
Locomotion distance, session 73.74.65.01.92.22.12.22.22.22.22.02.22.2
Stereotopy head waving bouts, day 70.70.81.1-0.6-1.0-0.9-0.9-0.9-1.0-0.8-0.8-0.9-1.0
Stereotopy head waving duration, day 71.01.21.5-0.8-1.2-1.1-1.1-1.1-1.1-1.0-1.0-1.1-1.2
Locomotion velocity, session 80.40.50.70.60.60.60.60.70.70.90.60.80.7
Locomotion distance, session 81.11.61.81.21.31.31.31.31.21.21.41.21.3
Degree of sensitization distance0.00.00.00.1-0.2-0.1-0.1-0.1-0.0-0.0-0.1-0.00.0
Degree of sensitization stereotypy0.60.71.0-0.6-0.8-0.7-0.8-0.8-1.0-0.8-0.7-0.9-1.0
Conditioned locomotion0.10.10.20.30.40.30.20.30.30.20.40.30.2
Cocaine response after cond. corrected0.00.00.10.30.00.20.10.10.30.1-0.00.10.0
Cocaine response after cond. not corrected0.30.30.50.70.60.60.60.60.70.50.40.50.5
Cocaine response before conditioning1.92.33.11.31.81.51.61.51.31.51.61.51.5
Saline control response0.00.00.1-0.20.20.00.10.10.20.20.10.20.3
Bone: connectivity density3.14.96.4-2.5-2.3-2.4-2.4-2.3-1.8-2.1-2.1-2.0-2.2
Bone: cortical apparent density0.30.41.11.10.70.70.50.60.90.50.30.50.3
Bone: cortical area6.710.212.4-3.5-3.3-3.4-3.3-3.2-3.4-3.0-2.9-2.9-3.0
Bone: cortical porosity0.10.10.2-0.40.0-0.2-0.2-0.3-0.4-0.40.0-0.3-0.0
Bone: cortical porosity0.00.00.1-0.20.2-0.00.0-0.0-0.1-0.20.2-0.10.1
Bone: cortical thickness2.13.54.4-2.1-2.0-2.0-1.9-1.8-2.1-1.7-1.7-1.7-1.8
Bone: cortical thickness0.20.20.40.10.20.30.40.40.40.60.40.50.6
Bone: cortical tissue density0.40.61.41.20.80.80.60.71.00.60.30.60.4
Condit. Reinf. active minus inactive responses0.10.10.20.20.40.20.30.20.20.20.40.30.4
Condit. Reinf. active-inactive response ratio0.20.20.3-0.6-0.2-0.5-0.5-0.5-0.4-0.5-0.2-0.4-0.3
Condit. Reinf. active responses0.70.91.01.00.90.91.00.90.90.91.00.91.0
Condit. Reinf. inactive responses2.83.54.42.11.72.01.91.91.91.91.61.81.8
Incentive salience index mean0.00.00.0-0.10.0-0.1-0.1-0.1-0.1-0.10.1-0.10.0
Condit. Reinf. lever presses0.30.50.6-0.6-0.7-0.7-0.7-0.7-0.7-0.8-0.7-0.8-0.6
Condit. Reinf. active minus inactive responses0.81.01.5-0.9-0.8-0.9-0.9-1.0-1.2-1.1-0.8-1.1-1.2
Condit. Reinf. active-inactive response ratio0.60.71.1-0.7-0.6-0.7-0.7-0.8-1.0-0.9-0.7-1.0-1.1
Condit. Reinf. active responses0.10.10.3-0.2-0.3-0.2-0.2-0.3-0.5-0.4-0.2-0.4-0.4
Condit. Reinf. inactive responses0.60.81.10.90.80.90.90.90.71.00.80.91.0
Condit. Reinf. lever presses0.00.00.1-0.3-0.1-0.1-0.1-0.1-0.2-0.0-0.3-0.00.0
Condit. Reinf. lever reinforcers received0.00.00.00.10.10.10.10.1-0.20.00.1-0.00.0
Conditioned reinforcement - actives0.50.81.20.90.81.00.90.91.10.80.90.80.8
Conditioned reinforcement - inactives4.05.87.02.32.42.42.52.42.42.42.62.32.3
Conditioned locomotion0.20.30.80.50.60.50.50.50.60.50.90.5-0.0
Patch foraging indifference point 0 sec5.09.310.52.73.23.03.13.12.93.03.23.23.1
Patch foraging indifference point AUC0.71.01.61.31.11.11.11.00.91.00.90.90.7
Delay disc. indifference point, 0s delay1.92.12.3-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.4-1.5-1.3
Delay disc. indifference point, 16s delay0.80.91.7-1.0-1.0-0.9-0.9-0.9-0.8-0.8-0.9-0.9-1.3
Delay disc. indifference point, 2s delay1.82.13.3-1.1-1.4-1.3-1.4-1.4-1.5-1.5-1.4-1.4-1.8
Delay disc. indifference point, 24s delay0.50.61.2-0.7-0.7-0.7-0.7-0.7-0.8-0.8-0.6-0.6-1.1
Delay disc. indifference point, 4s delay1.41.52.9-1.1-1.2-1.1-1.1-1.2-1.2-1.2-1.2-1.2-1.7
Delay disc. indifference point, 8s delay1.21.41.8-1.3-1.2-1.2-1.2-1.1-1.1-1.1-1.1-1.0-1.3
Indifference point function ln k3.86.67.2-2.7-2.6-2.6-2.6-2.6-2.4-2.6-2.5-2.5-2.5
Indifference point function log k3.86.67.2-2.7-2.6-2.6-2.6-2.6-2.4-2.6-2.5-2.5-2.5
Patch foraging total patch changes 0 sec4.68.69.92.63.12.93.03.02.82.93.13.12.9
Patch foraging total patch changes 12 sec6.28.08.42.82.82.92.92.92.72.92.92.92.7
Patch foraging total patch changes 18 sec5.88.910.52.93.23.03.13.02.83.02.93.02.8
Patch foraging total patch changes 24 sec3.25.46.42.22.52.32.42.42.02.32.42.42.3
Patch foraging total patch changes 6 sec6.610.111.13.13.33.23.23.22.93.23.33.33.1
Patch foraging time to switch 0 sec1.93.94.32.01.82.12.12.02.02.11.72.02.1
Patch foraging water rate 0 sec3.16.47.3-2.7-2.5-2.6-2.5-2.6-2.7-2.5-2.2-2.5-2.5
Patch foraging water rate 12 sec2.04.24.8-2.2-2.1-2.1-2.1-2.1-1.8-2.1-1.8-2.0-1.9
Patch foraging water rate 18 sec0.40.60.9-0.6-0.7-0.7-0.8-0.8-0.7-0.9-0.6-0.8-0.9
Patch foraging water rate 24 sec4.56.36.8-2.4-2.6-2.6-2.6-2.6-2.4-2.6-2.4-2.6-2.4
Patch foraging water rate 6 sec6.49.310.0-3.2-3.0-3.1-3.1-3.1-3.1-3.2-2.9-3.0-3.0
Seeking ratio, delayed vs. immediate footshock0.40.40.6-0.7-0.7-0.7-0.7-0.7-0.7-0.8-0.5-0.7-0.3
Distance traveled before self-admin2.02.73.21.61.71.61.61.71.61.61.81.71.3
Distance traveled after self-admin1.21.51.80.91.31.11.21.21.21.31.31.31.2
Extensor digitorum longus weight4.818.822.1-3.9-4.7-4.3-4.3-4.3-4.6-4.2-4.5-4.4-4.2
Bone: elastic displacement6.77.78.72.82.72.82.72.82.92.82.72.82.7
Bone: elastic work0.00.10.20.10.20.20.10.20.50.20.20.30.2
Bone: endosteal estimation7.115.518.4-4.3-4.1-4.1-4.1-4.0-3.8-3.9-3.6-3.8-3.7
Bone: endosteal perimeter6.714.316.5-4.1-3.9-3.9-3.9-3.8-3.8-3.7-3.5-3.6-3.6
Epididymis fat weight0.31.12.6-1.6-1.3-1.2-1.1-1.0-0.9-0.8-0.9-0.8-0.3
Delta time in closed arm before/after self-admin0.00.00.1-0.20.1-0.1-0.1-0.1-0.2-0.3-0.2-0.10.1
Delta time in open arm before/after self-admin1.21.11.50.91.11.11.11.11.21.21.01.10.8
Diff in mean of infusions in LGA sessions0.80.91.4-0.9-1.2-1.0-0.9-0.9-1.0-1.0-0.7-0.8-1.0
Delay discount exponential model param1.11.32.81.01.11.01.01.01.11.11.01.01.7
Extinction: sum of active levers before priming2.32.53.4-1.6-1.7-1.7-1.6-1.6-1.8-1.6-1.5-1.6-0.8
Active lever presses in extinction session 60.10.10.3-0.6-0.5-0.4-0.4-0.3-0.4-0.2-0.3-0.2-0.1
Bone: final force11.618.521.4-4.6-4.4-4.4-4.4-4.3-4.1-4.2-4.1-4.1-4.2
Bone: final moment13.020.824.1-4.9-4.6-4.7-4.7-4.6-4.3-4.5-4.4-4.4-4.5
Food consumed during 24 hour testing period1.52.12.9-1.7-1.2-1.6-1.5-1.5-1.4-1.6-1.3-1.4-1.4
Glucose0.30.50.80.50.40.60.70.70.60.90.90.80.7
Heart weight0.30.40.9-0.9-0.6-0.7-0.6-0.6-0.7-0.7-0.5-0.6-0.3
Delay discount hyperbolic model param1.11.22.70.91.11.01.01.01.11.11.01.01.6
Intermittent access intake day 1-15 change0.10.10.3-0.6-0.4-0.4-0.3-0.4-0.2-0.3-0.5-0.4-0.1
Intermittent access intake escalation0.30.50.8-0.9-0.8-0.7-0.7-0.7-0.6-0.7-0.9-0.8-0.4
Intermittent access intake escalation 20.10.10.2-0.4-0.3-0.3-0.2-0.3-0.3-0.2-0.4-0.30.1
Intermitt. access day 1 inactive lever presses0.00.10.30.60.40.40.40.40.50.30.30.2-0.1
Intermitt. access day 15 inactive lever presses0.00.00.00.10.20.10.1-0.00.2-0.2-0.1-0.20.1
Intermitt. access escalation Index0.00.00.00.2-0.2-0.1-0.2-0.10.1-0.0-0.0-0.1-0.1
Intermittent access day 1 total infusions1.01.72.21.31.51.31.31.31.41.21.51.30.6
Intermittent access day 15 total infusions0.40.60.70.70.80.80.80.80.80.80.80.70.5
Intermittent access terminal intake (last 3 days)0.60.80.90.80.90.91.00.90.90.90.90.80.6
Intermittent access total infusions1.11.31.61.11.21.21.31.21.11.11.31.10.8
Intermittent access day 1 locomotion0.91.11.71.01.11.01.01.11.21.01.31.10.1
Intermittent access day 15 total locomotion0.20.51.00.30.70.60.70.70.70.71.00.7-0.1
Intermittent access total locomotion2.12.53.41.41.71.61.61.61.71.61.91.60.8
Intermittent access standard deviation0.00.10.20.10.20.30.30.30.50.20.20.30.4
Left kidney weight1.57.18.6-2.9-2.9-2.7-2.6-2.7-2.7-2.7-2.6-2.7-2.0
Right kidney weight4.420.024.6-4.8-5.0-4.6-4.5-4.5-4.5-4.3-4.4-4.3-3.7
Cocaine induced anxiety2.02.93.7-1.9-1.9-1.8-1.8-1.7-1.6-1.6-1.8-1.6-1.3
Post-drug Anxiety3.63.95.1-2.3-2.1-2.1-2.0-2.0-2.0-1.9-1.9-1.9-1.3
Baseline Anxiety0.30.30.4-0.5-0.5-0.6-0.6-0.6-0.6-0.7-0.4-0.7-0.3
Tail length0.00.00.2-0.5-0.1-0.2-0.1-0.1-0.3-0.10.2-0.10.1
Length with tail1.66.99.0-3.0-2.7-2.8-2.7-2.7-2.7-2.6-2.4-2.5-2.2
Length without tail5.718.220.4-4.5-4.4-4.4-4.3-4.3-4.2-4.2-4.1-4.1-4.0
Times rat made contact with spout0.00.00.0-0.10.2-0.00.10.0-0.20.10.10.00.0
Lifetime Intake1.92.32.81.51.61.61.61.61.51.51.71.50.9
Liver weight, left10.617.520.6-4.5-4.2-4.3-4.2-4.2-4.3-4.2-3.9-4.0-3.9
Liver weight, right3.35.87.3-2.7-2.4-2.5-2.5-2.5-2.5-2.4-2.4-2.3-1.8
Locomotor activity1.21.93.01.31.31.41.41.41.21.31.51.41.7
Locomotor testing distance2.95.36.52.22.32.32.32.32.12.12.52.32.6
Locomotor testing rearing1.63.34.41.51.81.81.91.81.71.81.81.82.1
Locomotion in novel chamber4.65.96.7-2.4-2.4-2.4-2.4-2.4-2.5-2.3-2.6-2.5-2.4
Locomotion in novel chamber post-restriction0.20.30.5-0.5-0.4-0.5-0.5-0.5-0.4-0.5-0.7-0.5-0.4
Fecal boli incidents, locomotor time 10.71.01.60.91.11.01.11.01.01.01.31.00.6
Change in fecal boli incidents, locomotor task0.10.10.3-0.1-0.3-0.3-0.3-0.3-0.2-0.3-0.5-0.2-0.2
Time >=10cm from walls, locomotor time 10.40.40.60.50.60.60.60.70.70.60.70.80.6
Bouts of movement, locomotor time 10.00.00.10.20.10.10.00.00.0-0.10.20.00.3
Total resting periods, locomotor time 10.50.61.00.90.80.80.70.70.70.50.80.71.0
Rest time, locomotor task time 10.81.01.61.01.11.00.90.90.80.81.00.91.3
Distance moved, locomotor task time 10.00.00.10.2-0.00.10.10.10.10.20.10.0-0.3
Vertical activity count, locomotor time 10.41.01.5-1.0-1.2-1.1-1.1-1.0-0.9-0.9-0.7-1.0-1.1
Time >=10cm from walls, locomotor time 20.30.50.60.70.80.70.70.70.70.60.60.70.7
Bouts of movement, locomotor time 22.64.14.5-2.0-1.9-2.1-2.1-2.1-1.9-2.1-2.1-2.0-2.0
Total resting periods, locomotor time 22.64.55.0-2.1-2.1-2.2-2.2-2.2-2.0-2.2-2.2-2.1-2.0
Rest time, locomotor task time 20.20.30.90.50.50.50.50.50.10.30.80.50.9
Distance moved, locomotor task time 20.10.10.20.40.10.30.30.30.50.40.00.2-0.1
Vertical activity count, locomotor time 20.10.20.3-0.3-0.4-0.3-0.4-0.4-0.1-0.3-0.5-0.4-0.6
Light reinforcement 10.71.82.51.61.51.51.51.40.91.21.41.11.3
Light reinforcement 20.00.00.10.10.10.10.1-0.0-0.2-0.10.0-0.2-0.4
Bone: marrow area6.614.517.4-4.2-3.9-4.0-4.0-3.9-3.6-3.8-3.5-3.6-3.6
Bone: maximum diameter1.83.44.4-2.1-2.1-1.9-1.9-1.8-2.1-1.7-1.5-1.6-1.6
Bone: maximum force14.525.727.8-5.3-5.2-5.2-5.2-5.1-4.9-5.0-4.8-4.9-5.0
Bone: maximum moment16.228.430.8-5.6-5.4-5.5-5.5-5.4-5.1-5.3-5.1-5.1-5.2
Mean time between licks in bursts0.10.20.50.60.50.50.30.40.70.40.20.40.4
Mean num. licks in bursts0.40.61.1-1.0-0.6-0.8-0.7-0.7-0.6-0.6-0.9-0.7-1.0
Cd content in liver0.20.30.40.50.70.50.50.50.50.40.50.40.6
Co content in liver0.20.20.40.50.20.50.60.60.50.60.50.50.4
Cu content in liver0.20.20.6-0.8-0.5-0.5-0.5-0.4-0.3-0.4-0.2-0.2-0.1
Fe content in liver1.61.92.31.41.41.51.51.41.21.51.31.41.3
K content in liver0.20.20.40.30.20.40.40.40.40.50.40.50.6
Mg content in liver0.20.20.20.40.50.40.40.40.40.30.40.40.5
Mn content in liver0.00.00.10.20.10.20.10.2-0.00.00.20.20.3
Na content in liver0.00.00.1-0.3-0.3-0.10.0-0.0-0.10.1-0.1-0.00.0
Rb content in liver1.31.52.20.91.11.11.21.31.01.31.51.41.4
Se content in liver3.64.34.82.02.02.12.12.11.92.12.12.12.2
Sr content in liver0.60.50.8-0.9-0.6-0.8-0.8-0.7-0.6-0.7-0.7-0.6-0.7
Zn content in liver0.80.91.30.91.01.01.01.00.90.81.00.91.1
Bone: minimum diameter8.215.016.3-4.0-3.9-4.0-4.0-3.9-3.9-3.8-3.7-3.7-3.7
Time in familiar zone, hab. session 10.00.00.00.10.1-0.0-0.0-0.0-0.1-0.1-0.2-0.1-0.2
Time in novel zone, hab. session 10.00.00.1-0.1-0.1-0.1-0.2-0.1-0.3-0.20.1-0.1-0.0
Total zone transitions, hab. session 10.10.10.60.80.30.40.30.30.40.20.30.20.2
Total locomotion distance, hab. session 10.40.50.80.80.70.70.60.70.90.60.70.70.7
Locomotion velocity, hab. session 10.20.30.60.70.50.50.40.50.70.50.50.50.5
Time in familiar zone, hab. session 21.61.71.9-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.4-1.3-1.3
Time in novel zone, hab. session 21.81.82.21.41.31.31.31.31.31.31.51.41.4
Total zone transitions, hab. session 20.20.30.40.70.60.60.50.50.60.50.50.50.5
Total locomotion distance, hab. session 20.50.61.00.80.90.70.70.71.00.70.70.80.7
Locomotion velocity, hab. session 20.30.30.60.60.70.50.50.50.80.50.50.60.5
Novel to familiar place preference ratio1.31.51.9-1.1-1.1-1.2-1.2-1.2-1.4-1.2-1.1-1.2-1.2
Novelty place preference0.80.81.3-0.8-0.8-1.0-1.0-0.9-1.1-1.0-0.8-0.9-0.9
Time in novel zone, NPP test0.50.60.9-0.6-0.7-0.8-0.8-0.8-0.9-0.8-0.6-0.7-0.7
Total zone transitions, NPP test2.84.04.52.12.02.02.02.02.02.02.12.02.0
Total locomotion distance, NPP test3.85.15.72.42.42.32.22.22.42.22.22.22.2
Locomotion velocity, NPP test2.43.43.91.92.01.81.81.82.01.81.81.91.8
Intraocular pressure5.78.19.72.83.02.92.92.93.12.72.62.72.8
Delta distance traveled before/after self-admin0.10.10.3-0.6-0.1-0.2-0.2-0.2-0.10.0-0.3-0.10.1
Delta ambulatory time before/after self-admin0.00.00.3-0.40.1-0.00.00.00.10.2-0.10.00.5
Parametrial fat weight0.51.11.61.00.91.11.11.11.31.00.91.00.8
Pavlov. Cond. lever latency0.20.20.40.40.50.40.30.40.60.40.50.60.3
Pavlov. Cond. magazine entry latency1.11.42.3-1.0-1.2-1.1-1.0-1.1-1.5-1.3-1.1-1.3-1.0
Pavlov. Cond. change in total contacts1.41.52.1-1.0-1.3-1.1-1.1-1.2-1.5-1.2-1.2-1.4-1.2
Pavlov. Cond. index score1.01.22.1-1.0-1.2-1.0-0.9-1.0-1.4-1.1-1.1-1.2-0.9
Pavlov. Cond. latency score0.81.01.7-0.9-1.1-0.9-0.8-0.9-1.3-1.0-0.9-1.1-0.8
Pavlov. Cond. lever contacts0.10.20.5-0.3-0.4-0.3-0.2-0.4-0.7-0.4-0.4-0.5-0.3
Pavlov. Cond. magazine entry number0.60.71.50.81.00.80.70.81.20.90.70.90.7
Pavlov. Cond. intertrial magazine entries5.06.08.12.32.22.32.32.42.82.52.42.62.4
Pavlov. Cond. lever-magazine prob. diff.1.31.62.6-1.1-1.4-1.2-1.1-1.2-1.6-1.3-1.2-1.4-1.1
Pavlov. Cond. response bias0.30.40.9-0.5-0.7-0.5-0.5-0.6-0.9-0.7-0.5-0.7-0.5
Pavlov. Cond. lever latency0.81.11.5-0.9-1.0-1.0-1.1-1.1-0.9-1.2-0.9-1.2-1.1
Pavlov. Cond. magazine entry latency0.10.20.30.20.10.30.20.40.60.50.40.50.4
Pavlov. Cond. change in total contacts0.50.81.1-0.8-1.0-0.9-0.9-0.9-1.0-0.8-0.9-0.8-0.8
Pavlov. Cond. index score0.20.30.50.30.30.40.40.50.50.70.40.70.6
Pavlov. Cond. latency score0.30.30.60.40.30.50.50.60.60.80.50.80.7
Pavlov. Cond. lever contacts0.60.81.10.70.80.90.90.90.81.10.71.01.0
Pavlov. Cond. magazine entry number0.00.00.10.20.30.20.20.0-0.1-0.1-0.0-0.2-0.0
Pavlov. Cond. intertrial magazine entries1.82.73.51.31.81.71.91.71.31.61.71.61.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.20.10.30.30.40.40.60.30.60.5
Pavlov. Cond. response bias0.20.30.50.40.40.50.50.60.50.70.40.70.6
Time in closed arm before self-admin1.31.72.7-1.1-1.4-1.3-1.3-1.3-1.2-1.2-1.6-1.2-1.4
Time in closed arm after self-admin0.30.31.1-0.3-0.5-0.5-0.5-0.5-0.7-0.6-1.0-0.5-0.4
Time in open arm before self-admin0.40.40.70.80.60.60.60.60.60.60.80.60.6
Time in open arm after self-admin0.30.30.50.60.50.50.50.50.70.70.70.60.6
Bone: periosteal estimation9.921.025.1-5.0-4.7-4.8-4.7-4.6-4.6-4.5-4.2-4.3-4.3
Bone: periosteal perimeter9.316.118.5-4.3-4.2-4.2-4.1-4.0-4.2-3.9-3.7-3.8-3.8
Bone: post-yield work7.110.411.8-3.4-3.4-3.3-3.3-3.2-3.0-3.2-3.2-3.0-3.1
Progressive ratio test 1 active lever presses7.08.69.42.93.13.03.03.03.02.93.02.92.4
Progressive ratio test 1 breakpoint6.88.39.12.83.03.03.02.92.92.93.02.92.3
Progressive ratio test 1 inactive lever presses0.50.61.01.00.80.90.90.80.90.70.80.60.3
Progressive ratio test 2 active lever presses1.31.61.91.31.21.31.41.31.31.21.41.20.8
Progressive ratio test 2 breakpoint1.21.41.71.21.11.31.31.31.21.21.31.20.7
Progressive ratio test 2 inactive lever presses0.40.61.00.70.80.80.90.81.00.70.80.70.7
Incentive Sensitization - Responses0.60.91.2-0.9-1.1-0.9-0.9-0.9-0.9-1.0-0.8-0.9-1.0
Incentive Sensitization - Breakpoint0.50.70.9-0.8-1.0-0.8-0.8-0.8-0.8-0.9-0.8-0.9-0.9
Sum of active levers in priming session hrs 5-60.10.10.30.30.30.30.20.30.10.30.40.30.6
Progressive ratio1.32.12.31.51.41.51.41.51.51.51.31.51.4
Food seeking constrained by brief footshock3.13.84.32.01.92.01.92.02.12.11.82.01.8
Seeking ratio, punishment vs. effort0.00.10.1-0.3-0.2-0.2-0.2-0.3-0.3-0.2-0.2-0.3-0.2
Retroperitoneal fat weight0.83.24.51.41.61.71.81.82.02.01.71.92.1
Reaction time number correct0.81.62.6-1.6-1.2-1.4-1.3-1.3-1.2-1.3-1.3-1.1-1.2
Reaction time mean minus median3.07.48.62.72.92.82.82.82.62.52.92.62.5
Reaction time mean minus median AUC2.15.36.12.42.42.42.42.32.22.12.52.22.1
Reaction time num false alarms1.42.02.61.61.61.51.41.41.41.21.41.31.5
Reaction time num false alarms AUC1.62.43.31.81.71.61.51.51.51.31.51.41.6
Reaction time trials correct on left0.81.62.6-1.6-1.2-1.4-1.3-1.3-1.2-1.3-1.3-1.1-1.2
Reaction time trials on left0.71.32.1-1.5-1.0-1.2-1.2-1.1-1.0-1.1-1.1-0.9-1.0
Reaction time mean0.61.01.60.81.00.91.00.90.90.91.30.91.0
Reaction time mean AUC0.40.61.10.60.80.70.70.70.70.71.00.70.8
Median of all reaction times0.00.00.2-0.10.10.00.00.10.10.10.40.10.3
Reaction time omissions8.211.912.53.53.53.53.53.53.43.43.43.33.4
Reaction time false alarm rate1.92.74.22.01.71.71.61.61.51.41.61.41.7
Reaction time premature initiation rate3.44.75.72.22.22.32.32.22.12.21.72.12.4
Reaction time premature initiations1.01.82.71.21.41.41.51.41.41.30.91.31.6
Std. dev. reaction times3.87.18.22.72.82.72.72.72.52.52.92.52.6
Reaction time trials completed0.71.32.1-1.5-1.0-1.2-1.2-1.1-1.0-1.1-1.1-0.9-1.0
Reaction time trials AUC1.12.23.3-1.8-1.4-1.6-1.5-1.5-1.4-1.5-1.5-1.3-1.4
Run reversals in cocaine runway, females0.50.50.9-0.7-0.7-0.7-0.7-0.7-0.4-0.5-1.0-0.7-0.8
Run reversals in cocaine runway, males0.60.60.90.90.80.80.80.80.70.70.80.70.5
Latency to leave start box in cocaine runway0.00.00.10.3-0.00.10.00.10.00.10.0-0.00.1
Latency to leave start box in cocaine runway, F1.01.11.81.31.01.11.11.11.11.21.01.00.8
Latency to leave start box in cocaine runway, M1.81.71.9-1.3-1.3-1.3-1.4-1.3-1.4-1.4-1.3-1.3-1.0
Std. dev. time between licks in bursts1.21.61.91.31.41.31.31.31.11.21.31.21.3
Total sessions with >9 infusions2.22.73.21.81.71.81.71.71.71.61.81.60.9
Short access day 1 total inactive lever presses1.51.92.21.51.41.51.51.41.51.41.41.30.8
Short access day 10 total inactive lever presses0.00.10.1-0.2-0.0-0.2-0.2-0.3-0.3-0.3-0.2-0.3-0.0
Short access day 1 total infusions1.01.41.61.01.21.21.21.21.21.31.31.20.6
Short access day 10 total infusions1.82.32.91.61.71.61.61.61.71.51.51.50.6
Short access total infusions3.14.04.71.92.12.12.12.12.12.12.22.01.2
Short access day 1 locomotion0.40.50.60.70.70.70.70.70.80.70.80.7-0.6
Short access day 10 total locomotion0.20.40.60.60.70.70.70.70.80.70.70.70.0
Short access total locomotion1.01.21.61.11.31.11.11.11.21.11.21.10.1
One hour access (0.3 mA shock)0.30.40.7-0.6-0.6-0.5-0.5-0.5-0.7-0.6-0.4-0.7-0.8
Compulsive drug intake0.30.40.6-0.5-0.6-0.6-0.6-0.6-0.8-0.7-0.5-0.7-0.7
One hour access (shock baseline)0.20.30.4-0.6-0.6-0.5-0.4-0.5-0.5-0.5-0.5-0.5-0.6
Social response proportion0.10.10.20.10.40.30.40.30.40.40.40.30.4
Social responses4.76.07.82.52.62.62.62.52.02.22.52.32.8
Social time0.40.50.8-0.9-0.7-0.7-0.7-0.7-0.7-0.7-0.9-0.7-0.2
Soleus weight0.92.83.2-1.7-1.8-1.7-1.6-1.6-1.7-1.6-1.6-1.6-1.7
Bone: stiffness19.631.933.3-5.7-5.7-5.8-5.8-5.7-5.5-5.6-5.6-5.5-5.6
Tibialis anterior weight3.010.214.2-2.5-3.5-3.0-3.0-3.1-3.8-3.1-3.3-3.4-3.1
Time to tail flick, vehicle, before self-admin1.51.54.31.11.21.21.21.11.01.11.01.12.1
Time to tail flick, vehicle, after self-admin0.30.40.7-0.5-0.8-0.5-0.5-0.6-0.7-0.6-0.8-0.6-0.7
Time to tail flick, test, before self-admin0.30.30.60.60.40.50.50.50.60.60.30.50.8
Time to tail flick, test, after self-admin1.11.22.1-1.0-1.0-1.1-1.1-1.1-0.9-1.0-1.4-1.0-1.0
Delta time to tail flick, vehicle, before/after SA0.80.81.9-0.9-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.7-1.4
Delta time to tail flick, test, before/after SA0.60.61.1-0.8-0.6-0.8-0.8-0.8-0.6-0.9-0.9-0.8-1.0
Tibia length4.612.817.8-4.2-3.7-3.9-3.7-3.7-3.2-3.4-3.3-3.4-3.2
Ambulatory time before self-admin2.33.44.21.92.01.91.91.91.71.82.01.91.4
Ambulatory time after self-admin1.92.23.01.21.71.41.51.51.41.61.51.51.5
Bone: tissue strength1.51.51.8-1.1-1.2-1.3-1.3-1.3-1.2-1.3-1.1-1.2-1.3
Total heroin consumption0.50.61.0-1.0-0.9-0.9-0.8-0.8-0.9-0.6-0.7-0.7-0.6
Bone: trabecular number3.55.87.7-2.8-2.4-2.6-2.6-2.5-2.0-2.3-2.2-2.2-2.4
Bone: trabecular spacing1.01.31.81.31.21.21.31.20.71.01.11.01.2
Bone: trabecular thickness0.30.40.7-0.4-0.4-0.5-0.6-0.6-0.6-0.7-0.8-0.7-0.8
Bone: trabecular tissue density0.71.11.7-0.4-0.6-0.8-1.0-1.0-1.1-1.2-1.2-1.3-1.3
Water consumed over 24 hours0.00.00.2-0.40.1-0.2-0.1-0.1-0.1-0.1-0.1-0.0-0.1
Number of responses in last shaping day0.10.10.60.20.20.0-0.0-0.00.10.0-0.2-0.1-0.8