Hub : Genes

LOC102553253

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC102553253 0.18 0.1 7.1e-04 0.14 0.12 0.12 0.14 3.4e-04 7.9e-04 6.9e-04 3.7e-04
2 LHb gene expression LOC102553253 0.47 0.14 3.8e-05 0.13 0.14 0.16 0.11 5.4e-04 3.9e-04 1.2e-04 1.2e-03
3 Brain mRNA stability LOC102553253 0.23 0.08 2.3e-14 0.14 0.17 0.16 0.1 7.9e-13 1.9e-15 6.3e-15 9.1e-10
4 PL gene expression LOC102553253 0.06 0.03 1.1e-03 0.02 0.03 0.03 0.03 3.2e-03 2.2e-04 1.4e-04 2.5e-04
5 PL mRNA stability LOC102553253 0.09 0.04 3.6e-07 0.06 0.06 0.05 0.06 1.3e-07 1.9e-07 5.0e-06 9.5e-07
6 IC mRNA stability LOC102553253 0.13 0.08 7.7e-03 0.02 0.02 0.01 0.03 3.3e-02 5.8e-02 1.6e-01 2.6e-02
7 pVTA mRNA stability LOC102553253 0.1 0.05 8.1e-04 0 0.04 0.03 0.01 1.7e-01 5.3e-04 1.7e-03 4.3e-02
8 NAcc mRNA stability LOC102553253 0.06 0.03 9.9e-04 0.01 0.02 0.01 0.02 3.1e-03 6.2e-04 3.4e-03 6.8e-04
9 NAcc gene expression LOC102553253 0.07 0.03 1.6e-13 0.08 0.08 0.08 0.08 9.6e-12 1.3e-12 2.3e-12 1.4e-12
10 BLA mRNA stability LOC102553253 0.1 0.05 1.3e-04 0.03 0.06 0.05 0.02 1.1e-02 4.4e-04 1.0e-03 2.4e-02
11 pVTA gene expression LOC102553253 0.12 0.06 3.1e-05 0.06 0.05 0.08 0.06 8.7e-06 1.1e-04 8.3e-07 2.6e-05
12 Adipose mRNA stability LOC102553253 0.04 0.03 1.3e-04 0.02 0.02 0.03 0.02 3.2e-03 1.6e-03 6.8e-04 1.8e-03
13 Brain gene expression LOC102553253 0.08 0.05 5.8e-05 0.06 0.04 0.04 0.05 4.3e-06 5.9e-05 5.9e-05 2.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density6.310.917.44.24.1-3.63.7-4.0-2.5-2.8-3.43.3-2.80.8-3.2-2.9
Area under the delay curve0.91.02.7-1.2-1.71.3-0.51.01.40.91.2-0.80.6-0.10.90.4
BMI with tail1.96.611.23.13.2-2.32.1-3.1-0.2-1.2-1.63.3-2.9-1.3-3.4-3.1
BMI without tail0.20.72.10.60.3-0.81.4-0.7-1.0-1.5-0.9-0.1-0.11.00.10.2
Body weight6.729.147.46.86.1-6.76.9-6.4-5.7-5.8-5.54.0-4.63.7-3.5-2.0
Weight adjusted by age0.20.32.00.30.3-0.50.6-0.4-0.6-0.5-1.40.3-0.00.6-0.20.3
Bone surface4.58.213.63.53.2-3.13.7-3.6-2.5-2.6-3.02.7-2.51.1-2.7-2.1
Bone volume5.19.215.33.93.6-2.83.6-3.8-1.8-1.9-2.73.4-3.20.2-3.3-3.0
Breakpoint value in progressive ratio session0.30.30.9-0.2-1.0-0.00.50.0-0.8-0.70.0-0.60.00.80.50.8
Number of licking bursts0.81.33.60.90.4-1.41.1-1.1-1.8-1.5-1.90.3-0.21.6-0.3-0.3
Context. condit. distance diff. score0.80.92.61.31.3-0.61.6-1.0-0.8-0.0-0.11.1-1.60.4-0.5-0.6
Locomotion velocity, session 10.20.20.8-0.4-0.60.0-0.00.2-0.5-0.1-0.4-0.50.30.60.90.8
Locomotion distance, session 10.30.31.1-0.5-0.60.1-0.50.3-0.0-0.5-0.9-0.61.10.50.50.4
Locomotion velocity, session 20.91.14.60.50.5-1.10.9-0.9-1.3-1.5-2.20.00.51.4-0.20.2
Locomotion distance, session 21.21.74.5-0.4-0.6-0.60.20.2-1.2-1.6-1.7-1.41.72.11.31.6
Locomotion velocity, session 30.30.41.90.6-0.3-0.10.4-0.7-0.10.4-0.10.9-1.4-0.5-0.6-0.7
Locomotion distance, session 30.30.30.8-0.5-0.80.1-0.20.6-0.0-0.30.4-0.90.50.80.90.7
Stereotopy head waving bouts, day 31.11.33.40.71.0-1.01.7-1.1-1.7-1.0-1.80.3-0.21.40.30.9
Stereotopy head waving duration, day 30.10.20.9-0.20.00.50.5-0.2-0.20.9-0.20.5-0.3-0.30.20.5
Locomotion velocity, session 71.11.23.3-1.0-0.81.8-0.31.31.11.71.8-0.60.2-0.60.90.4
Locomotion distance, session 71.51.84.7-1.5-1.01.8-0.71.81.01.52.2-1.30.9-0.31.50.9
Stereotopy head waving bouts, day 71.92.14.8-1.6-2.00.8-0.91.5-0.3-0.20.5-2.11.70.92.02.2
Stereotopy head waving duration, day 70.50.71.9-1.0-1.40.4-0.60.7-0.3-0.1-0.0-1.00.90.50.91.2
Locomotion velocity, session 80.50.61.4-0.6-0.70.2-0.50.7-0.5-0.2-0.4-1.00.90.91.21.2
Locomotion distance, session 81.01.43.71.01.1-1.21.6-0.9-1.8-1.3-1.50.1-0.21.90.30.6
Degree of sensitization distance0.60.61.5-0.8-0.11.2-0.31.00.81.01.0-0.50.7-0.50.60.4
Degree of sensitization stereotypy0.60.62.2-1.0-1.50.6-0.90.90.20.00.4-1.00.90.10.80.8
Conditioned locomotion0.30.41.0-0.9-0.40.5-0.50.70.10.50.2-0.71.00.30.70.9
Cocaine response after cond. corrected0.70.92.9-0.1-0.20.6-1.10.21.50.60.70.5-0.3-1.7-0.8-1.6
Cocaine response after cond. not corrected0.70.93.0-0.1-0.40.5-1.10.01.20.60.70.5-0.5-1.7-1.0-1.7
Cocaine response before conditioning0.10.10.40.0-0.60.00.3-0.0-0.60.10.4-0.1-0.50.3-0.10.3
Saline control response1.92.57.4-0.8-0.4-0.20.50.9-1.9-1.1-0.6-2.01.92.32.32.7
Bone: connectivity density4.67.213.13.13.3-3.13.6-3.1-3.0-2.9-3.11.9-1.61.9-1.6-1.1
Bone: cortical apparent density0.20.31.30.51.2-0.5-0.2-0.30.40.1-0.00.7-0.3-0.7-0.5-0.6
Bone: cortical area1.93.05.22.11.4-1.72.0-2.3-1.9-1.4-1.61.8-1.90.2-1.7-1.5
Bone: cortical porosity0.20.20.7-0.4-0.70.7-0.30.3-0.30.1-0.6-0.50.80.60.20.3
Bone: cortical porosity0.40.51.1-0.8-0.91.1-0.50.7-0.10.6-0.1-0.70.90.50.60.6
Bone: cortical thickness1.62.64.41.91.7-1.71.7-2.1-1.8-1.2-1.61.7-1.60.1-1.7-1.3
Bone: cortical thickness1.01.22.4-1.5-1.10.8-0.91.2-0.10.20.9-1.51.50.21.31.5
Bone: cortical tissue density0.20.31.30.41.2-0.4-0.3-0.20.50.2-0.00.7-0.2-0.8-0.5-0.6
Condit. Reinf. active minus inactive responses0.91.02.41.41.5-0.90.7-1.1-0.7-0.0-0.71.3-1.3-0.2-0.9-0.7
Condit. Reinf. active-inactive response ratio0.80.82.30.91.5-0.10.2-0.50.21.00.31.4-1.3-1.1-1.0-0.8
Condit. Reinf. active responses0.40.51.01.00.9-0.70.3-0.8-0.6-0.3-0.80.8-0.8-0.0-0.6-0.4
Condit. Reinf. inactive responses0.10.21.2-0.4-1.10.4-0.40.10.1-0.1-0.3-0.30.20.00.20.2
Incentive salience index mean0.10.20.70.70.2-0.20.1-0.4-0.4-0.0-0.10.5-0.8-0.1-0.5-0.3
Condit. Reinf. lever presses0.20.31.5-0.2-1.20.9-0.40.20.70.70.30.1-0.3-0.5-0.5-0.5
Condit. Reinf. active minus inactive responses1.01.33.8-1.2-1.20.6-0.21.2-0.40.20.6-1.51.21.21.82.0
Condit. Reinf. active-inactive response ratio1.11.33.1-1.3-1.40.8-0.31.3-0.30.30.5-1.61.20.91.81.6
Condit. Reinf. active responses0.81.14.1-0.7-0.80.10.10.9-0.6-0.30.3-1.51.01.51.62.0
Condit. Reinf. inactive responses0.20.31.10.20.3-0.50.10.1-0.4-0.70.0-0.60.30.90.41.0
Condit. Reinf. lever presses0.10.10.60.0-0.60.20.40.20.10.00.8-0.3-0.30.30.00.2
Condit. Reinf. lever reinforcers received0.71.03.8-0.6-0.60.00.20.8-0.6-0.40.4-1.40.91.61.51.9
Conditioned reinforcement - actives1.83.16.31.81.6-2.22.2-1.9-1.9-2.4-2.50.7-0.62.0-0.70.1
Conditioned reinforcement - inactives1.21.73.01.51.2-1.71.4-1.6-1.2-1.7-1.60.9-0.81.1-1.2-0.4
Conditioned locomotion0.20.20.60.8-0.3-0.50.3-0.3-0.5-0.8-0.4-0.2-0.20.6-0.00.4
Patch foraging indifference point 0 sec0.50.92.61.61.0-1.01.1-1.0-0.6-0.4-0.51.0-1.40.1-0.8-0.5
Patch foraging indifference point AUC0.20.20.50.30.3-0.30.7-0.7-0.3-0.3-0.70.5-0.30.3-0.7-0.4
Delay disc. indifference point, 0s delay0.10.10.40.0-0.2-0.20.6-0.40.2-0.1-0.10.3-0.40.30.5-0.2
Delay disc. indifference point, 16s delay0.40.41.5-0.3-0.80.70.10.11.20.80.80.3-0.5-0.7-0.0-0.6
Delay disc. indifference point, 2s delay1.92.14.8-2.0-2.21.6-1.31.61.10.81.7-1.71.3-0.11.21.1
Delay disc. indifference point, 24s delay0.50.61.7-0.4-1.21.1-0.10.41.31.10.80.0-0.2-0.60.2-0.3
Delay disc. indifference point, 4s delay0.50.62.2-0.5-1.01.1-0.30.41.50.90.9-0.0-0.0-0.70.1-0.5
Delay disc. indifference point, 8s delay0.91.01.9-1.2-1.31.0-1.01.01.40.81.2-1.00.9-0.11.00.7
Indifference point function ln k0.30.61.50.80.6-1.00.5-0.5-1.2-0.9-0.8-0.2-0.11.20.20.7
Indifference point function log k0.30.61.50.80.6-1.00.5-0.5-1.2-0.9-0.8-0.2-0.11.20.20.7
Patch foraging total patch changes 0 sec0.30.62.01.40.8-0.81.0-0.8-0.6-0.2-0.40.8-1.30.2-0.6-0.3
Patch foraging total patch changes 12 sec1.01.33.11.41.0-0.81.4-1.3-0.2-0.1-0.41.5-1.8-0.5-1.3-1.2
Patch foraging total patch changes 18 sec0.30.51.20.60.80.10.3-0.50.50.9-0.11.1-0.8-0.7-0.8-0.8
Patch foraging total patch changes 24 sec0.00.10.30.3-0.10.10.3-0.10.10.30.20.3-0.50.3-0.4-0.3
Patch foraging total patch changes 6 sec0.00.10.20.1-0.40.00.10.2-0.10.10.4-0.1-0.40.20.10.3
Patch foraging time to switch 0 sec0.71.43.8-1.2-1.41.4-1.10.91.91.41.6-0.10.0-1.5-0.0-0.5
Patch foraging water rate 0 sec1.12.35.11.92.2-1.81.7-1.4-2.3-1.4-1.60.7-0.81.6-0.40.2
Patch foraging water rate 12 sec0.61.34.61.01.3-1.31.3-0.8-2.1-1.3-1.20.1-0.21.20.40.4
Patch foraging water rate 18 sec0.60.91.7-0.8-1.31.1-0.61.3-0.10.70.6-1.20.80.31.31.3
Patch foraging water rate 24 sec1.41.94.50.51.5-1.50.6-0.3-2.1-1.8-1.5-0.81.02.11.11.7
Patch foraging water rate 6 sec0.81.13.21.41.8-0.81.7-1.0-1.0-0.1-0.51.1-1.30.5-0.5-0.4
Seeking ratio, delayed vs. immediate footshock1.31.64.5-1.7-1.40.6-2.11.40.60.31.5-1.51.3-0.41.40.6
Distance traveled before self-admin0.71.03.20.5-0.10.6-0.7-0.21.21.30.61.0-0.9-1.8-1.4-0.9
Distance traveled after self-admin0.40.51.7-0.5-0.91.2-0.60.70.61.30.4-0.10.2-0.5-0.2-0.3
Extensor digitorum longus weight1.14.510.42.82.3-2.03.2-2.5-2.2-1.4-2.12.0-2.41.2-1.4-1.0
Bone: elastic displacement0.30.41.40.10.9-0.3-0.10.2-0.3-0.6-0.8-0.51.20.70.40.6
Bone: elastic work1.52.05.51.11.6-2.00.9-0.9-2.1-2.4-1.7-0.30.51.70.10.6
Bone: endosteal estimation0.71.54.00.60.7-1.51.1-0.7-1.9-2.0-1.3-0.50.31.90.50.9
Bone: endosteal perimeter0.71.62.81.51.1-1.61.6-1.4-1.7-1.6-1.30.6-1.01.2-0.4-0.1
Epididymis fat weight1.86.312.32.92.5-1.72.9-3.1-0.5-0.3-1.33.5-3.5-0.4-3.4-3.1
Delta time in closed arm before/after self-admin0.20.10.40.60.2-0.20.6-0.3-0.4-0.2-0.20.1-0.50.3-0.40.2
Delta time in open arm before/after self-admin2.62.64.8-2.2-1.81.7-2.01.91.81.21.5-1.31.6-0.81.80.2
Diff in mean of infusions in LGA sessions0.81.02.8-0.8-1.31.3-0.60.70.91.41.7-0.2-0.5-1.30.50.2
Delay discount exponential model param1.21.33.51.31.9-1.50.7-1.1-1.7-1.1-1.40.9-0.60.3-0.8-0.4
Extinction: sum of active levers before priming0.91.03.01.40.7-0.50.6-1.00.8-0.2-0.31.2-1.3-0.4-1.4-1.7
Active lever presses in extinction session 60.90.92.01.10.6-0.81.4-1.2-0.6-0.3-0.41.1-1.3-0.4-1.3-0.6
Bone: final force0.20.31.00.40.1-0.70.6-0.4-1.0-1.0-0.8-0.20.10.80.10.1
Bone: final moment0.20.30.80.50.1-0.60.5-0.5-0.8-0.9-0.8-0.00.10.6-0.1-0.1
Food consumed during 24 hour testing period1.01.43.6-1.3-1.91.1-1.91.30.30.40.6-1.41.30.01.31.0
Glucose0.30.51.40.3-0.1-0.60.0-0.90.2-0.1-0.30.9-0.9-0.9-1.2-1.1
Heart weight1.42.15.91.41.4-2.11.1-1.5-1.9-2.4-1.70.3-0.21.5-0.50.5
Delay discount hyperbolic model param1.31.43.81.51.9-1.50.8-1.2-1.6-1.1-1.51.0-0.70.3-0.9-0.5
Intermittent access intake day 1-15 change0.71.43.21.11.3-1.01.8-1.2-1.7-0.8-1.60.7-0.31.4-1.00.2
Intermittent access intake escalation0.61.32.51.11.4-1.01.5-1.2-1.4-0.8-1.60.8-0.41.1-1.1-0.0
Intermittent access intake escalation 20.40.51.70.81.3-0.40.9-0.7-0.30.1-0.90.9-0.30.3-0.8-0.2
Intermitt. access day 1 inactive lever presses0.41.42.51.61.5-1.51.1-1.2-1.3-1.2-1.10.9-0.90.5-1.5-0.5
Intermitt. access day 15 inactive lever presses0.30.51.1-0.6-1.00.8-0.40.30.90.81.00.3-0.3-1.1-0.7-0.4
Intermitt. access escalation Index0.10.10.4-0.20.10.3-0.60.40.30.30.5-0.20.3-0.5-0.3-0.1
Intermittent access day 1 total infusions0.61.02.6-0.9-0.90.1-0.40.8-0.1-0.8-0.1-1.51.61.31.31.3
Intermittent access day 15 total infusions0.81.13.90.30.4-0.91.0-0.4-1.5-1.5-1.3-0.50.82.00.21.1
Intermittent access terminal intake (last 3 days)0.20.31.20.20.0-0.30.5-0.1-0.6-0.7-0.7-0.40.71.10.10.8
Intermittent access total infusions0.30.41.1-0.1-0.3-0.30.00.1-0.3-1.0-0.5-0.81.01.00.30.8
Intermittent access day 1 locomotion0.40.51.2-0.6-0.70.1-0.80.70.0-0.40.2-1.01.10.10.91.0
Intermittent access day 15 total locomotion0.91.73.8-1.3-1.70.8-1.21.60.2-0.30.5-2.01.91.11.21.7
Intermittent access total locomotion1.01.22.9-0.8-1.30.5-1.51.30.8-0.50.5-1.61.70.30.91.1
Intermittent access standard deviation0.81.63.11.71.3-1.11.8-1.6-1.1-0.8-1.31.3-1.10.4-1.6-0.7
Left kidney weight4.119.232.95.64.8-5.75.1-5.1-5.0-5.0-4.03.0-3.93.4-2.5-1.2
Right kidney weight5.123.238.26.25.1-6.25.4-5.9-5.3-5.4-4.73.7-4.52.9-3.3-2.0
Cocaine induced anxiety0.60.81.5-0.8-1.21.2-0.90.90.71.01.2-0.80.4-0.50.41.1
Post-drug Anxiety1.51.63.5-1.1-1.61.8-1.21.21.81.41.9-0.70.4-1.10.50.4
Baseline Anxiety0.30.32.20.2-0.10.0-0.1-0.10.8-0.10.50.4-0.5-0.6-0.4-1.5
Tail length2.710.732.41.91.0-3.33.5-1.5-5.4-4.6-3.1-1.50.45.71.93.1
Length with tail5.624.556.75.14.0-6.16.4-4.6-7.5-6.3-5.41.2-2.56.5-0.41.2
Length without tail6.922.137.66.15.8-5.95.5-5.6-4.9-4.7-4.53.7-4.23.0-3.1-1.9
Times rat made contact with spout0.60.72.0-0.2-0.1-0.1-0.00.4-1.1-0.4-0.5-0.90.91.41.21.3
Lifetime Intake0.30.31.1-0.1-0.2-0.4-0.10.0-0.2-1.1-0.5-0.60.90.90.30.8
Liver weight, left2.84.69.62.21.7-2.53.0-2.5-3.1-2.2-2.41.3-1.72.2-1.1-0.4
Liver weight, right1.93.36.32.41.3-2.22.1-2.0-2.4-2.5-2.00.7-1.31.9-0.9-0.5
Locomotor activity0.81.33.31.41.2-1.11.8-1.2-1.3-1.1-1.20.6-0.81.5-0.4-0.1
Locomotor testing distance0.71.32.71.51.6-1.11.5-1.2-0.7-0.5-1.01.2-1.10.8-1.1-0.7
Locomotor testing rearing0.10.10.60.40.80.20.7-0.10.10.5-0.00.4-0.10.2-0.20.0
Locomotion in novel chamber2.63.38.3-1.3-1.4-0.1-1.01.3-0.9-1.7-1.0-2.72.92.22.12.5
Locomotion in novel chamber post-restriction1.21.96.60.70.2-1.30.7-0.5-1.1-2.6-2.0-1.11.42.30.81.0
Fecal boli incidents, locomotor time 11.11.52.81.01.0-1.51.7-1.5-1.6-1.1-1.51.0-1.20.8-0.8-0.9
Change in fecal boli incidents, locomotor task0.60.61.4-0.3-0.80.7-1.20.90.50.41.1-0.80.6-0.90.40.6
Time >=10cm from walls, locomotor time 10.30.31.6-0.10.2-0.8-0.70.2-0.2-1.3-0.1-0.60.80.3-0.10.7
Bouts of movement, locomotor time 10.20.20.70.10.1-0.00.8-0.3-0.80.4-0.30.4-0.50.4-0.4-0.0
Total resting periods, locomotor time 10.10.10.40.00.00.10.4-0.1-0.40.5-0.10.4-0.50.1-0.7-0.3
Rest time, locomotor task time 10.30.30.8-0.2-0.60.5-0.90.80.10.20.1-0.80.80.20.40.6
Distance moved, locomotor task time 10.10.20.40.00.2-0.00.6-0.60.40.1-0.30.7-0.6-0.00.1-0.7
Vertical activity count, locomotor time 10.51.12.11.21.1-0.91.3-1.5-0.4-0.4-0.91.4-1.3-0.1-0.8-1.3
Time >=10cm from walls, locomotor time 20.10.10.50.30.3-0.50.40.0-0.3-0.7-0.1-0.2-0.10.70.10.2
Bouts of movement, locomotor time 21.72.87.01.91.7-1.82.6-2.1-1.8-1.6-1.91.2-1.31.1-1.1-0.4
Total resting periods, locomotor time 21.73.06.52.01.7-1.92.5-2.3-1.7-1.6-1.81.5-1.60.7-1.5-0.8
Rest time, locomotor task time 20.50.72.1-0.5-1.10.6-1.51.00.20.30.9-0.90.6-0.70.60.8
Distance moved, locomotor task time 20.70.82.50.80.9-0.51.6-1.0-0.1-0.2-1.40.9-0.61.3-0.3-0.7
Vertical activity count, locomotor time 22.43.36.42.12.0-1.82.5-2.4-1.2-1.0-2.22.0-1.60.9-1.4-1.4
Light reinforcement 10.41.13.2-0.5-0.91.5-1.31.01.81.51.0-0.10.3-1.3-0.10.1
Light reinforcement 20.60.82.20.80.30.3-0.0-0.60.61.1-0.31.4-1.2-1.1-1.2-1.5
Bone: marrow area0.61.43.90.60.7-1.51.0-0.6-1.8-2.0-1.3-0.50.41.80.50.9
Bone: maximum diameter1.93.65.72.31.7-2.12.3-2.4-2.3-1.9-2.11.5-1.70.9-1.4-1.0
Bone: maximum force0.20.41.40.50.0-0.80.6-0.6-1.2-1.1-0.7-0.0-0.20.8-0.10.0
Bone: maximum moment0.20.41.20.60.1-0.80.6-0.7-1.1-1.0-0.80.1-0.20.6-0.2-0.2
Mean time between licks in bursts0.00.10.5-0.50.00.1-0.10.2-0.20.1-0.0-0.30.60.1-0.00.7
Mean num. licks in bursts0.71.21.9-1.1-0.31.3-1.01.30.81.31.2-0.91.0-0.61.31.4
Cd content in liver0.30.30.90.10.4-0.30.20.2-0.5-0.5-0.7-0.50.71.00.70.7
Co content in liver0.60.71.7-1.1-1.31.0-0.90.90.70.7-0.1-0.71.2-0.30.50.3
Cu content in liver1.61.94.01.61.6-0.51.6-1.6-0.20.3-0.82.0-1.8-0.4-1.8-1.6
Fe content in liver5.46.612.23.33.5-1.93.0-3.0-1.2-0.3-1.53.4-3.3-0.1-2.7-2.6
K content in liver0.10.10.40.2-0.60.40.10.10.50.10.1-0.1-0.10.30.1-0.2
Mg content in liver0.70.81.8-0.7-1.11.3-0.61.00.81.11.0-0.70.4-0.21.00.6
Mn content in liver0.20.21.00.10.3-0.10.10.1-0.6-0.2-0.5-0.40.50.71.00.7
Na content in liver0.20.21.30.2-0.2-0.60.3-0.1-0.0-1.1-0.2-0.40.11.1-0.0-0.2
Rb content in liver2.93.38.7-1.6-0.72.6-1.41.82.42.93.0-0.30.4-2.30.50.2
Se content in liver2.22.69.21.71.1-0.40.6-1.40.70.4-0.12.3-2.2-1.2-2.5-3.0
Sr content in liver1.91.63.91.41.0-1.41.7-1.3-1.8-1.6-2.00.5-0.41.3-0.4-0.4
Zn content in liver3.03.35.12.21.8-2.11.9-2.2-2.2-1.7-2.31.5-1.51.2-1.5-0.9
Bone: minimum diameter0.00.10.20.1-0.30.00.3-0.3-0.4-0.1-0.20.2-0.3-0.2-0.3-0.3
Time in familiar zone, hab. session 10.40.41.01.01.0-0.60.1-0.6-0.1-0.4-0.70.7-0.5-0.3-0.7-0.8
Time in novel zone, hab. session 10.20.20.60.10.7-0.30.8-0.2-0.7-0.2-0.00.1-0.10.50.10.1
Total zone transitions, hab. session 12.73.78.6-1.6-1.90.3-0.61.7-1.1-1.20.1-2.92.42.72.52.8
Total locomotion distance, hab. session 11.21.73.4-1.6-1.40.9-0.81.5-0.10.10.9-1.81.61.21.71.8
Locomotion velocity, hab. session 11.92.75.1-2.2-2.31.5-1.42.00.70.71.4-2.01.80.71.81.8
Time in familiar zone, hab. session 20.70.82.00.71.10.30.0-0.40.41.10.71.2-1.3-1.4-0.6-0.9
Time in novel zone, hab. session 20.30.31.0-0.8-1.0-0.1-0.30.3-0.2-0.5-0.3-0.70.90.50.30.4
Total zone transitions, hab. session 21.21.63.8-0.4-0.3-0.7-0.40.2-0.9-1.9-1.7-1.41.91.91.11.2
Total locomotion distance, hab. session 21.01.34.1-1.2-0.90.1-1.20.9-0.0-0.8-0.6-1.52.01.21.31.3
Locomotion velocity, hab. session 21.01.44.5-1.2-0.9-0.0-1.10.8-0.1-0.9-0.7-1.62.11.31.21.3
Novel to familiar place preference ratio0.10.10.4-0.00.4-0.50.4-0.2-0.2-0.6-0.3-0.10.40.3-0.2-0.1
Novelty place preference0.10.10.30.00.5-0.50.4-0.3-0.2-0.6-0.30.00.20.2-0.2-0.3
Time in novel zone, NPP test0.20.20.50.20.7-0.70.4-0.4-0.4-0.7-0.40.10.10.2-0.2-0.3
Total zone transitions, NPP test0.91.34.50.1-0.2-0.80.5-0.1-1.5-1.4-1.6-1.00.92.11.11.2
Total locomotion distance, NPP test0.81.02.2-1.1-1.50.7-0.71.0-0.1-0.10.2-1.51.21.21.31.1
Locomotion velocity, NPP test1.11.53.2-1.4-1.80.8-0.61.2-0.3-0.20.1-1.81.61.51.51.5
Intraocular pressure0.20.30.70.50.9-0.40.7-0.5-0.8-0.00.20.5-0.8-0.0-0.10.0
Delta distance traveled before/after self-admin1.21.23.4-1.3-0.90.8-0.31.2-0.60.1-0.1-1.51.51.21.91.3
Delta ambulatory time before/after self-admin0.60.81.7-1.3-1.21.1-0.31.1-0.20.70.1-0.91.00.51.30.6
Parametrial fat weight0.81.83.61.81.5-1.61.9-1.6-0.5-1.3-0.71.1-1.60.7-1.1-0.9
Pavlov. Cond. lever latency2.73.48.72.33.0-2.71.6-2.1-1.5-1.7-1.51.7-1.50.5-1.4-1.2
Pavlov. Cond. magazine entry latency1.92.45.2-1.4-2.01.0-0.81.6-0.8-0.20.4-2.21.71.82.22.3
Pavlov. Cond. change in total contacts1.11.13.6-1.0-1.91.7-0.51.20.71.31.2-0.80.2-0.30.70.6
Pavlov. Cond. index score1.92.46.8-1.8-2.61.8-1.11.80.20.71.1-1.91.40.61.71.7
Pavlov. Cond. latency score2.22.87.7-2.0-2.81.9-1.31.90.40.81.0-2.11.70.61.81.8
Pavlov. Cond. lever contacts3.74.511.4-2.6-3.43.0-1.82.51.71.92.0-2.01.6-0.41.61.4
Pavlov. Cond. magazine entry number2.02.55.31.52.0-1.30.7-1.80.5-0.2-1.02.2-1.5-1.5-2.3-2.3
Pavlov. Cond. intertrial magazine entries0.20.20.50.40.6-0.3-0.2-0.20.60.10.00.5-0.3-0.7-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.62.06.2-1.6-2.51.8-1.01.60.30.81.0-1.61.20.41.41.4
Pavlov. Cond. response bias1.92.45.8-1.7-2.41.7-0.91.7-0.00.71.1-2.01.30.81.91.9
Pavlov. Cond. lever latency0.40.51.40.70.8-1.00.2-1.0-0.9-0.8-1.20.7-0.40.0-0.6-0.4
Pavlov. Cond. magazine entry latency0.10.10.30.30.3-0.10.5-0.2-0.2-0.2-0.10.1-0.10.5-0.3-0.3
Pavlov. Cond. change in total contacts0.10.20.70.10.3-0.10.80.2-0.4-0.30.1-0.40.20.80.50.5
Pavlov. Cond. index score0.10.20.5-0.3-0.30.30.20.60.0-0.10.5-0.70.50.70.50.5
Pavlov. Cond. latency score0.10.20.5-0.3-0.30.30.10.6-0.1-0.00.5-0.70.40.70.50.5
Pavlov. Cond. lever contacts0.50.72.0-0.7-0.81.2-0.31.01.21.01.4-0.60.3-0.30.40.1
Pavlov. Cond. magazine entry number0.10.10.5-0.1-0.10.0-0.4-0.1-0.20.1-0.30.2-0.1-0.70.00.1
Pavlov. Cond. intertrial magazine entries0.50.82.2-0.9-0.90.2-0.91.0-0.2-0.20.3-1.21.10.51.31.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.7-0.2-0.20.20.40.4-0.1-0.10.4-0.60.40.80.40.4
Pavlov. Cond. response bias0.60.82.4-0.8-0.91.2-0.31.11.20.91.6-0.80.4-0.10.50.2
Time in closed arm before self-admin1.72.25.81.31.6-1.81.5-1.6-2.0-1.6-2.40.8-0.41.5-0.6-0.1
Time in closed arm after self-admin2.62.86.31.61.4-1.91.9-1.4-2.3-2.0-2.50.4-0.42.4-0.40.5
Time in open arm before self-admin0.10.10.60.10.3-0.30.30.0-0.7-0.30.2-0.30.10.20.20.8
Time in open arm after self-admin2.02.23.6-1.6-1.41.8-1.61.71.81.41.9-1.01.1-1.31.40.1
Bone: periosteal estimation1.02.04.61.51.1-1.81.7-1.6-2.2-2.0-1.70.6-0.71.2-0.6-0.2
Bone: periosteal perimeter1.01.83.11.71.2-1.41.6-1.7-1.6-1.2-1.21.2-1.60.4-1.0-0.8
Bone: post-yield work0.30.51.10.4-0.40.10.2-0.70.00.5-0.51.0-1.0-0.9-1.0-1.0
Progressive ratio test 1 active lever presses0.70.92.50.3-0.0-0.91.0-0.5-1.5-1.5-1.2-0.50.51.60.11.0
Progressive ratio test 1 breakpoint0.70.92.40.3-0.0-0.81.0-0.5-1.5-1.4-1.1-0.50.51.60.11.0
Progressive ratio test 1 inactive lever presses0.50.82.20.50.6-1.10.9-0.7-1.5-1.3-1.00.1-0.01.0-0.60.6
Progressive ratio test 2 active lever presses2.22.59.51.11.1-2.20.9-0.8-1.9-3.1-1.7-0.70.92.4-0.01.0
Progressive ratio test 2 breakpoint2.12.49.21.11.1-2.20.8-0.8-1.8-3.0-1.7-0.70.92.3-0.11.0
Progressive ratio test 2 inactive lever presses1.42.27.80.91.2-2.01.5-1.1-1.8-2.8-1.5-0.30.32.1-0.80.8
Incentive Sensitization - Responses1.31.88.51.11.3-2.20.4-0.8-1.1-2.9-1.2-0.50.61.7-0.50.3
Incentive Sensitization - Breakpoint1.31.78.11.11.2-2.10.3-0.7-1.0-2.8-1.1-0.50.71.6-0.50.4
Sum of active levers in priming session hrs 5-60.80.81.90.91.0-1.21.0-1.0-1.0-1.4-0.90.2-0.40.8-0.3-0.0
Progressive ratio0.40.72.3-0.7-1.50.2-0.60.5-0.3-0.50.2-1.20.70.70.51.5
Food seeking constrained by brief footshock0.70.92.51.11.6-0.80.6-1.1-0.0-0.1-1.11.2-0.80.1-1.3-0.7
Seeking ratio, punishment vs. effort0.81.15.21.12.3-1.00.9-1.0-0.5-0.3-1.31.2-0.50.2-0.7-1.1
Retroperitoneal fat weight1.77.113.23.32.8-2.33.3-3.3-0.9-1.3-1.23.2-3.60.3-3.2-3.0
Reaction time number correct0.61.23.21.41.1-1.50.6-0.9-1.8-1.8-1.40.0-0.11.0-0.10.4
Reaction time mean minus median2.15.29.1-3.0-2.82.4-1.42.80.81.22.2-2.92.30.72.92.5
Reaction time mean minus median AUC2.66.511.1-3.3-3.22.4-1.83.10.81.22.6-3.22.60.63.22.8
Reaction time num false alarms0.10.10.5-0.1-0.7-0.1-0.70.1-0.2-0.3-0.3-0.30.20.3-0.00.0
Reaction time num false alarms AUC0.00.10.30.2-0.50.0-0.4-0.1-0.1-0.0-0.10.1-0.4-0.1-0.4-0.4
Reaction time trials correct on left0.61.23.21.41.1-1.50.6-0.9-1.8-1.8-1.40.0-0.11.0-0.10.4
Reaction time trials on left0.61.13.11.31.0-1.40.6-0.8-1.7-1.7-1.3-0.00.01.0-0.00.4
Reaction time mean3.45.59.2-3.0-2.43.0-2.42.63.02.72.9-1.51.6-1.81.30.2
Reaction time mean AUC3.25.18.5-2.9-2.12.9-2.22.52.92.72.9-1.41.5-1.81.30.2
Median of all reaction times3.24.510.9-2.4-1.72.7-2.22.03.32.92.6-0.60.9-2.50.4-0.7
Reaction time omissions1.31.93.1-1.8-1.21.5-1.31.70.81.21.5-1.31.3-0.71.61.4
Reaction time false alarm rate0.20.20.6-0.2-0.80.4-0.40.10.60.70.30.3-0.5-0.5-0.4-0.6
Reaction time premature initiation rate6.89.516.5-3.8-4.12.8-3.53.71.51.32.4-3.83.50.23.33.3
Reaction time premature initiations3.66.412.0-2.8-3.11.8-2.73.00.30.31.4-3.53.20.83.13.3
Std. dev. reaction times2.85.210.1-3.2-2.92.6-1.72.81.61.62.7-2.52.0-0.22.41.7
Reaction time trials completed0.61.13.11.31.0-1.40.6-0.8-1.7-1.7-1.3-0.00.01.0-0.00.4
Reaction time trials AUC0.61.12.71.31.0-1.40.6-0.9-1.6-1.7-1.30.1-0.20.8-0.20.2
Run reversals in cocaine runway, females0.30.30.6-0.6-0.40.8-0.70.60.60.80.5-0.20.6-0.70.2-0.0
Run reversals in cocaine runway, males1.31.32.51.31.2-0.91.6-1.4-1.0-0.3-1.31.2-1.00.6-1.4-0.6
Latency to leave start box in cocaine runway0.60.72.80.20.00.7-0.00.30.61.51.70.6-1.3-0.70.10.3
Latency to leave start box in cocaine runway, F0.81.03.91.01.0-0.21.1-0.8-0.10.80.71.4-2.0-0.6-1.1-0.3
Latency to leave start box in cocaine runway, M0.90.92.8-0.6-0.60.8-1.11.20.40.81.0-1.00.70.41.71.1
Std. dev. time between licks in bursts0.10.20.4-0.3-0.7-0.3-0.40.1-0.1-0.50.0-0.50.40.3-0.30.5
Total sessions with >9 infusions1.31.63.51.41.2-1.51.6-1.7-1.4-1.3-1.91.0-0.70.9-0.9-0.1
Short access day 1 total inactive lever presses1.72.27.61.11.5-1.91.7-1.2-2.8-2.2-1.30.2-0.41.7-0.50.6
Short access day 10 total inactive lever presses0.10.20.70.60.8-0.40.3-0.4-0.1-0.40.30.4-0.6-0.2-0.60.0
Short access day 1 total infusions1.01.43.10.91.3-1.41.4-1.5-1.3-1.4-1.80.9-0.40.9-0.9-0.2
Short access day 10 total infusions0.30.41.10.2-0.1-0.50.5-0.3-0.6-0.9-0.9-0.30.41.10.00.9
Short access total infusions0.20.31.10.30.2-0.70.3-0.5-0.3-1.1-0.90.00.40.6-0.20.2
Short access day 1 locomotion0.50.72.20.70.6-0.91.0-1.0-0.7-0.9-1.50.7-0.40.5-1.0-0.1
Short access day 10 total locomotion0.61.11.81.30.9-1.11.4-1.3-1.2-1.0-1.10.9-0.90.3-1.3-0.5
Short access total locomotion0.10.10.30.30.1-0.30.3-0.2-0.5-0.4-0.5-0.00.00.1-0.30.5
One hour access (0.3 mA shock)0.80.92.5-0.4-0.4-0.50.00.2-0.4-1.4-0.9-1.11.41.60.41.4
Compulsive drug intake2.12.54.8-2.0-1.61.9-2.21.91.61.81.6-1.11.3-1.11.20.6
One hour access (shock baseline)0.50.82.90.60.2-1.01.0-0.6-0.9-1.7-1.1-0.30.31.5-0.20.8
Social response proportion1.01.12.70.21.0-0.61.4-0.0-1.7-1.0-0.8-0.60.61.61.21.4
Social responses2.02.67.8-1.6-1.61.10.21.7-0.40.31.0-2.21.51.62.52.8
Social time0.60.82.1-0.8-0.91.40.10.61.31.41.20.00.0-1.10.0-0.1
Soleus weight0.72.25.42.01.9-1.32.3-1.7-1.6-0.9-1.21.3-1.50.7-0.9-0.7
Bone: stiffness0.20.31.9-0.5-1.40.1-0.30.3-0.5-0.40.4-0.80.10.40.50.5
Tibialis anterior weight1.55.210.02.42.8-2.73.2-2.3-3.0-2.5-2.71.1-1.22.4-0.40.0
Time to tail flick, vehicle, before self-admin0.30.40.90.20.20.5-0.20.31.00.80.90.4-0.5-0.8-0.0-1.0
Time to tail flick, vehicle, after self-admin0.10.10.50.60.0-0.50.4-0.50.1-0.40.00.3-0.70.40.2-0.1
Time to tail flick, test, before self-admin2.12.24.51.51.0-1.91.6-1.5-1.9-2.1-1.90.6-0.71.9-1.0-0.1
Time to tail flick, test, after self-admin0.60.62.1-0.4-0.50.9-1.00.51.41.01.00.1-0.1-1.10.0-0.3
Delta time to tail flick, vehicle, before/after SA0.30.30.90.70.1-0.30.2-0.70.4-0.10.10.7-0.9-0.5-0.9-0.6
Delta time to tail flick, test, before/after SA2.22.24.7-1.4-1.11.9-1.91.52.21.91.8-0.70.8-1.80.80.1
Tibia length1.64.59.92.32.1-2.92.5-2.0-3.1-3.0-2.00.6-1.02.3-0.60.2
Ambulatory time before self-admin0.40.61.80.3-0.10.5-0.5-0.21.21.00.30.8-0.7-1.3-1.0-0.8
Ambulatory time after self-admin0.40.41.9-0.6-1.01.2-0.20.40.51.40.10.2-0.0-0.5-0.2-0.5
Bone: tissue strength1.41.43.61.61.9-1.60.5-1.3-0.8-1.1-1.41.1-0.90.1-0.8-1.0
Total heroin consumption1.11.34.5-1.2-2.11.5-0.90.91.41.21.2-0.60.2-0.81.0-0.0
Bone: trabecular number3.86.311.23.13.3-2.83.1-3.0-2.3-2.3-2.72.2-2.01.0-1.9-1.7
Bone: trabecular spacing0.91.22.8-1.1-1.31.2-1.71.01.31.21.6-0.50.2-1.40.40.0
Bone: trabecular thickness5.06.210.23.23.0-2.72.9-3.1-1.6-2.1-2.52.5-2.20.8-2.6-2.3
Bone: trabecular tissue density0.20.31.50.0-0.80.1-0.50.30.30.01.2-0.2-0.7-0.3-0.1-0.3
Water consumed over 24 hours0.81.14.30.40.2-0.80.3-0.1-1.7-1.5-1.2-0.90.92.10.60.8
Number of responses in last shaping day0.60.61.31.00.9-0.41.0-1.0-0.10.1-0.81.1-0.9-0.4-0.9-0.8