Hub : Genes

LOC102553253

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC102553253 0.21 0.11 4.2e-04 0.18 0.14 0.16 0.17 4.9e-05 2.6e-04 1.3e-04 5.6e-05
2 PL mRNA stability LOC102553253 0.1 0.05 7.2e-07 0.05 0.07 0.06 0.06 8.4e-06 5.7e-08 1.3e-07 4.7e-07
3 LHb gene expression LOC102553253 0.44 0.15 2.6e-04 0.07 0.07 0 0.05 1.0e-02 9.7e-03 2.6e-01 2.6e-02
4 Adipose gene expression LOC102553253 0.02 0.02 6.3e-03 0.01 0 0 0 4.4e-02 1.5e-01 1.6e-01 1.5e-01
5 Brain mRNA stability LOC102553253 0.23 0.08 7.3e-14 0.11 0.18 0.17 0.09 1.1e-10 2.5e-16 1.8e-15 1.9e-08
6 PL gene expression LOC102553253 0.04 0.03 1.1e-03 0.03 0.04 0.04 0.04 9.9e-05 9.2e-05 4.2e-05 3.1e-05
7 BLA mRNA stability LOC102553253 0.08 0.05 1.5e-03 0.03 0.05 0.02 0.02 9.7e-03 1.0e-03 1.8e-02 2.6e-02
8 NAcc mRNA stability LOC102553253 0.09 0.05 6.8e-04 0.01 0.04 0.02 0.01 5.7e-02 5.9e-05 3.4e-03 2.4e-02
9 NAcc gene expression LOC102553253 0.09 0.05 1.6e-13 0.1 0.12 0.11 0.11 3.3e-12 1.4e-13 5.5e-13 5.1e-13
10 Adipose mRNA stability LOC102553253 0.04 0.03 1.6e-05 0.02 0.03 0.03 0.02 1.7e-03 1.9e-04 4.2e-04 9.0e-04
11 Brain gene expression LOC102553253 0.04 0.03 5.5e-03 0.04 0.03 0.03 0.02 1.6e-04 2.1e-03 3.7e-04 3.0e-03
12 pVTA mRNA stability LOC102553253 0.24 0.12 8.8e-05 0.08 0.1 0.1 0.09 1.9e-04 5.9e-05 6.4e-05 7.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density6.811.319.0-3.4-3.94.0-4.4-3.43.9-2.9-3.03.4-3.12.9-0.7
Area under the delay curve1.41.53.01.71.6-1.71.21.4-0.90.71.5-0.91.0-0.50.4
BMI with tail2.06.510.7-2.9-2.32.5-2.9-1.63.2-2.7-1.43.3-2.92.80.6
BMI without tail0.10.31.0-0.0-0.30.1-0.1-0.60.80.3-0.4-0.30.8-0.6-1.0
Body weight6.828.546.9-6.8-6.56.1-6.5-6.66.8-5.2-4.34.0-3.31.9-2.7
Weight adjusted by age0.60.74.1-0.2-1.01.2-0.7-0.80.4-0.1-2.00.1-0.1-0.7-0.1
Bone surface5.18.915.3-3.1-3.53.6-3.9-3.13.6-2.7-2.72.9-2.52.2-0.7
Bone volume6.010.317.4-3.4-3.33.4-4.2-2.73.7-3.3-2.43.6-3.33.20.1
Breakpoint value in progressive ratio session0.30.30.80.60.4-0.50.2-0.00.10.20.7-0.60.9-0.9-0.6
Number of licking bursts0.80.93.6-0.5-1.01.0-1.0-1.31.0-0.4-1.90.1-0.10.1-0.9
Context. condit. distance diff. score1.01.23.3-1.7-0.81.0-1.0-0.51.4-1.80.21.1-0.80.51.1
Locomotion velocity, session 10.20.20.50.2-0.10.10.1-0.2-0.10.3-0.6-0.60.6-0.7-0.3
Locomotion distance, session 10.40.51.50.80.1-0.10.1-0.2-0.31.2-1.2-0.60.6-0.1-1.1
Locomotion velocity, session 20.91.05.3-0.2-1.01.0-1.0-1.20.70.4-2.3-0.00.10.2-1.3
Locomotion distance, session 21.21.75.30.8-0.60.40.1-1.2-0.11.8-1.7-1.51.6-1.3-2.3
Locomotion velocity, session 30.40.41.4-1.0-0.10.2-0.60.00.7-1.2-0.10.8-0.80.40.8
Locomotion distance, session 30.40.51.00.30.3-0.60.7-0.2-0.70.60.5-1.00.9-0.9-1.0
Stereotopy head waving bouts, day 31.11.34.0-0.7-1.51.8-1.2-1.21.5-0.2-2.00.10.1-0.8-0.1
Stereotopy head waving duration, day 30.40.53.0-0.1-0.10.7-0.30.50.8-0.5-0.60.4-0.3-0.31.7
Locomotion velocity, session 71.11.22.80.51.5-1.21.11.7-0.3-0.01.6-0.40.5-0.41.6
Locomotion distance, session 71.41.74.60.91.5-1.41.71.5-1.10.82.1-1.01.2-0.90.9
Stereotopy head waving bouts, day 72.12.44.41.91.4-1.51.40.8-1.11.70.9-2.02.1-2.1-0.7
Stereotopy head waving duration, day 70.50.61.61.20.6-0.60.40.2-0.40.8-0.1-1.01.0-1.3-0.6
Locomotion velocity, session 80.40.51.50.50.2-0.20.4-0.1-0.60.7-0.5-1.11.0-1.2-0.6
Locomotion distance, session 80.60.92.1-0.9-1.41.4-0.8-1.51.1-0.3-1.3-0.00.3-0.5-0.8
Degree of sensitization distance0.50.51.30.70.9-0.60.81.1-0.40.50.9-0.30.5-0.21.0
Degree of sensitization stereotypy0.70.71.71.30.9-1.10.60.5-0.50.90.5-1.01.0-0.9-0.6
Conditioned locomotion0.30.41.61.30.00.10.60.2-0.61.0-0.2-0.70.5-0.60.1
Cocaine response after cond. corrected0.70.71.90.81.2-1.20.21.2-0.4-0.11.00.5-0.61.40.7
Cocaine response after cond. not corrected0.70.82.30.71.2-1.20.11.1-0.4-0.31.00.6-0.71.50.7
Cocaine response before conditioning0.10.10.3-0.50.1-0.30.1-0.10.2-0.60.5-0.00.2-0.10.0
Saline control response1.92.48.61.0-0.30.10.9-0.8-0.51.8-0.5-2.32.4-2.9-1.7
Bone: connectivity density4.57.112.9-2.7-3.63.6-3.3-3.43.3-1.8-2.61.9-1.51.5-1.3
Bone: cortical apparent density0.30.41.0-0.8-0.90.9-0.4-0.6-0.0-0.2-0.40.6-1.00.9-0.0
Bone: cortical area2.63.97.5-2.1-2.02.0-2.7-1.82.5-2.3-1.52.0-1.61.5-0.1
Bone: cortical porosity0.40.51.01.00.9-0.70.30.9-0.50.7-0.8-0.40.6-0.50.4
Bone: cortical porosity0.70.71.51.21.1-0.80.71.1-0.70.9-0.4-0.70.8-0.80.6
Bone: cortical thickness2.03.25.7-1.8-2.02.1-2.4-1.72.1-1.8-1.51.8-1.61.3-0.1
Bone: cortical thickness1.41.62.91.50.6-0.71.40.3-1.41.70.9-1.61.6-1.7-0.9
Bone: cortical tissue density0.30.41.0-0.7-0.80.9-0.3-0.5-0.1-0.2-0.40.6-1.00.90.1
Condit. Reinf. active minus inactive responses1.11.31.9-1.3-1.21.4-1.1-0.71.0-1.4-0.71.2-1.40.90.7
Condit. Reinf. active-inactive response ratio1.01.02.5-1.0-0.81.1-0.50.10.5-1.20.21.3-1.61.11.6
Condit. Reinf. active responses0.50.60.9-0.9-0.80.9-0.8-0.60.8-0.8-0.90.8-0.90.90.2
Condit. Reinf. inactive responses0.10.10.50.40.7-0.70.20.40.00.3-0.4-0.20.40.2-0.2
Incentive salience index mean0.20.20.7-0.6-0.20.2-0.5-0.10.5-0.8-0.00.6-0.60.70.3
Condit. Reinf. lever presses0.30.41.00.21.0-0.9-0.00.90.2-0.30.10.4-0.21.00.5
Condit. Reinf. active minus inactive responses1.11.33.81.40.5-0.61.20.1-0.91.10.5-1.71.6-2.0-0.7
Condit. Reinf. active-inactive response ratio1.41.52.81.51.0-1.11.30.5-1.01.20.5-1.71.7-1.7-0.5
Condit. Reinf. active responses0.71.03.50.80.1-0.40.8-0.4-0.70.80.3-1.51.4-1.9-1.1
Condit. Reinf. inactive responses0.20.31.1-0.4-0.40.10.1-0.7-0.20.10.1-0.50.5-0.8-1.1
Condit. Reinf. lever presses0.10.10.60.00.2-0.5-0.1-0.1-0.0-0.40.7-0.10.2-0.3-0.3
Condit. Reinf. lever reinforcers received0.71.03.40.80.1-0.40.7-0.5-0.70.80.4-1.51.4-1.8-1.3
Conditioned reinforcement - actives2.42.46.2-1.2-1.91.8-1.7-2.12.0-0.9-2.50.8-0.50.3-1.3
Conditioned reinforcement - inactives0.80.91.8-0.9-1.01.0-1.1-1.11.1-0.6-1.40.8-0.80.6-0.7
Conditioned locomotion0.10.10.3-0.30.2-0.30.1-0.00.3-0.5-0.4-0.20.2-0.5-0.0
Patch foraging indifference point 0 sec0.50.81.9-1.3-0.80.8-0.8-0.70.9-1.4-0.40.9-1.00.60.3
Patch foraging indifference point AUC0.20.31.2-0.5-0.30.4-0.3-0.31.1-0.2-0.80.4-0.20.6-0.1
Delay disc. indifference point, 0s delay0.00.10.20.40.1-0.1-0.00.10.4-0.30.30.2-0.10.10.2
Delay disc. indifference point, 16s delay0.50.51.10.50.9-0.90.21.0-0.1-0.41.10.3-0.20.50.9
Delay disc. indifference point, 2s delay2.32.64.11.91.8-2.01.81.4-1.41.52.0-1.51.7-1.2-0.3
Delay disc. indifference point, 24s delay0.60.61.51.01.1-1.00.41.2-0.0-0.10.80.10.10.21.1
Delay disc. indifference point, 4s delay0.60.61.51.11.2-1.10.51.2-0.30.10.90.10.00.40.8
Delay disc. indifference point, 8s delay1.31.42.71.61.4-1.41.31.1-1.31.01.3-1.11.0-0.60.1
Indifference point function ln k0.30.51.4-0.4-1.00.9-0.3-1.20.2-0.2-0.7-0.20.1-0.9-0.9
Indifference point function log k0.30.51.4-0.4-1.00.9-0.3-1.20.2-0.2-0.7-0.20.1-0.9-0.9
Patch foraging total patch changes 0 sec0.30.51.4-1.1-0.70.7-0.5-0.60.7-1.2-0.20.7-0.70.40.3
Patch foraging total patch changes 12 sec1.01.22.5-1.5-0.70.7-0.8-0.41.4-1.6-0.31.3-1.41.50.7
Patch foraging total patch changes 18 sec0.40.52.0-0.6-0.10.4-0.20.50.5-0.7-0.40.9-1.01.01.4
Patch foraging total patch changes 24 sec0.10.10.3-0.00.3-0.30.10.30.1-0.40.20.2-0.20.50.4
Patch foraging total patch changes 6 sec0.10.10.40.40.3-0.40.30.1-0.3-0.20.6-0.30.3-0.2-0.0
Patch foraging time to switch 0 sec0.71.22.80.81.6-1.50.81.6-1.00.11.70.1-0.10.61.1
Patch foraging water rate 0 sec1.01.64.2-1.3-2.02.0-1.1-1.81.1-0.6-1.30.5-0.4-0.2-0.8
Patch foraging water rate 12 sec0.61.02.4-0.7-1.51.5-1.0-1.50.8-0.4-1.2-0.00.1-0.6-0.9
Patch foraging water rate 18 sec0.70.92.00.81.0-0.91.10.9-0.90.70.6-1.11.1-1.40.4
Patch foraging water rate 24 sec1.21.74.00.3-1.81.6-0.3-1.90.11.0-1.2-1.01.0-1.6-2.0
Patch foraging water rate 6 sec0.71.01.8-1.1-1.21.4-1.0-0.71.1-1.3-0.50.9-0.90.20.7
Seeking ratio, delayed vs. immediate footshock1.71.95.21.21.1-1.51.30.7-2.31.41.8-1.61.3-1.0-0.7
Distance traveled before self-admin0.50.51.8-0.60.3-0.20.10.7-0.0-0.90.30.8-1.00.91.3
Distance traveled after self-admin0.30.31.20.50.7-0.50.10.9-0.4-0.1-0.20.1-0.10.51.1
Extensor digitorum longus weight1.24.79.3-3.0-2.22.4-2.6-1.93.1-2.6-1.92.0-1.61.20.3
Bone: elastic displacement0.30.41.20.3-0.60.60.1-0.5-0.01.0-1.1-0.40.3-0.5-0.8
Bone: elastic work1.21.64.6-0.8-1.91.6-0.9-2.10.70.3-1.2-0.40.3-0.8-2.1
Bone: endosteal estimation0.61.33.6-0.4-1.51.2-0.9-1.90.90.0-1.2-0.40.6-0.9-1.8
Bone: endosteal perimeter0.81.73.3-1.3-1.61.4-1.8-1.81.7-1.3-1.30.7-0.40.1-1.0
Epididymis fat weight3.27.513.5-2.8-1.82.1-3.2-1.23.6-3.5-1.13.7-3.43.21.3
Delta time in closed arm before/after self-admin0.40.41.3-1.1-0.70.8-0.5-0.60.8-0.7-0.70.5-0.40.20.1
Delta time in open arm before/after self-admin3.53.47.22.72.2-2.32.02.0-2.31.92.0-1.21.1-0.50.1
Diff in mean of infusions in LGA sessions1.31.53.50.91.7-1.40.91.9-0.8-0.21.7-0.20.2-0.31.9
Delay discount exponential model param1.71.83.4-1.8-1.81.8-1.3-1.61.0-0.8-1.80.9-1.00.4-0.6
Extinction: sum of active levers before priming0.80.82.4-1.2-0.30.2-1.0-0.30.7-1.20.01.3-1.21.60.1
Active lever presses in extinction session 61.81.73.4-1.3-1.11.2-1.6-0.71.8-1.8-0.41.6-1.51.10.8
Bone: final force0.30.40.9-0.5-0.80.7-0.8-0.90.9-0.4-0.80.20.00.4-0.7
Bone: final moment0.30.50.8-0.6-0.80.8-0.9-0.90.9-0.4-0.80.3-0.10.4-0.5
Food consumed during 24 hour testing period1.41.72.91.71.5-1.61.51.1-1.51.50.6-1.41.4-1.0-0.3
Glucose0.60.81.6-0.5-1.00.9-1.3-0.90.9-1.0-1.00.9-1.01.0-0.2
Heart weight1.11.56.3-0.3-1.10.50.5-1.6-0.10.8-0.2-1.11.3-2.0-2.5
Delay discount hyperbolic model param1.71.83.4-1.8-1.81.8-1.3-1.51.0-0.8-1.71.0-1.10.6-0.5
Intermittent access intake day 1-15 change0.40.30.90.2-0.70.90.1-0.50.40.6-0.9-0.30.4-0.9-0.3
Intermittent access intake escalation0.40.41.10.0-0.91.1-0.0-0.70.50.6-1.0-0.30.4-0.8-0.4
Intermittent access intake escalation 20.30.31.10.3-0.81.10.3-0.40.20.7-0.6-0.20.2-0.60.1
Intermitt. access day 1 inactive lever presses0.20.20.8-0.9-0.20.2-0.3-0.10.3-0.60.00.5-0.50.50.2
Intermitt. access day 15 inactive lever presses0.40.51.20.01.1-1.00.11.00.3-0.51.00.6-0.30.70.7
Intermitt. access escalation Index0.00.00.1-0.10.00.10.20.2-0.00.00.20.1-0.10.20.4
Intermittent access day 1 total infusions0.81.02.31.50.5-0.70.8-0.0-0.41.5-0.0-1.11.4-0.9-1.3
Intermittent access day 15 total infusions1.21.33.21.3-0.20.10.8-0.6-0.01.8-0.6-1.31.6-1.7-1.7
Intermittent access terminal intake (last 3 days)0.70.82.21.50.3-0.20.90.1-0.11.5-0.3-0.91.1-1.2-0.8
Intermittent access total infusions1.61.84.22.00.8-1.01.20.2-0.82.00.1-1.51.8-1.5-1.6
Intermittent access day 1 locomotion0.90.91.81.40.9-1.01.10.7-1.01.20.5-1.01.0-0.9-0.4
Intermittent access day 15 total locomotion2.72.94.72.01.5-1.71.70.9-1.72.01.0-2.02.2-2.0-1.0
Intermittent access total locomotion2.62.94.72.21.7-2.01.81.0-1.72.01.0-1.92.0-1.5-1.2
Intermittent access standard deviation0.30.31.60.1-0.60.8-0.2-0.41.3-0.2-0.60.5-0.20.00.2
Left kidney weight3.710.521.2-4.1-4.13.5-3.8-4.63.8-3.1-2.51.9-1.50.5-2.7
Right kidney weight6.417.928.2-5.3-4.94.5-5.2-5.25.0-4.4-4.13.3-2.81.9-2.2
Cocaine induced anxiety0.10.10.20.10.3-0.40.20.2-0.3-0.10.10.2-0.30.2-0.1
Post-drug Anxiety1.51.72.71.61.4-1.61.60.9-1.61.51.1-1.11.1-0.7-0.8
Baseline Anxiety0.40.51.40.51.0-1.00.61.0-0.40.21.2-0.10.20.30.6
Tail length1.33.912.1-0.6-1.50.9-0.6-2.81.20.5-1.6-1.92.5-2.9-3.5
Length with tail4.014.636.8-4.7-4.94.1-4.1-6.14.2-2.9-3.40.7-0.0-1.4-4.3
Length without tail8.117.834.0-5.8-5.04.6-5.2-4.84.9-4.9-2.63.6-3.31.9-1.3
Times rat made contact with spout0.40.51.90.4-0.0-0.00.5-0.2-0.30.8-0.6-1.01.0-1.4-0.6
Lifetime Intake0.80.92.51.60.4-0.60.8-0.1-0.31.5-0.3-0.91.2-1.0-1.5
Liver weight, left2.74.27.8-2.3-2.32.5-2.5-2.02.8-2.4-1.81.9-1.61.00.4
Liver weight, right2.74.510.1-2.6-2.32.4-2.6-2.23.2-2.3-2.11.6-1.20.7-0.2
Locomotor activity0.61.02.7-1.3-1.21.2-0.9-1.21.6-0.9-1.00.5-0.30.0-0.2
Locomotor testing distance0.61.02.0-1.3-1.11.3-0.9-0.71.4-1.0-1.01.0-1.00.60.5
Locomotor testing rearing0.10.10.60.2-0.10.30.10.30.50.0-0.00.3-0.2-0.00.8
Locomotion in novel chamber2.22.75.61.40.7-1.01.1-0.1-1.62.4-0.5-2.22.2-2.3-2.2
Locomotion in novel chamber post-restriction1.31.67.10.0-1.00.7-0.4-1.60.61.1-1.6-0.81.2-1.3-2.7
Fecal boli incidents, locomotor time 11.11.22.0-0.9-1.41.4-1.4-1.31.3-1.2-1.30.7-0.70.4-0.1
Change in fecal boli incidents, locomotor task1.01.02.40.81.2-1.41.11.1-1.10.81.5-0.60.5-0.40.0
Time >=10cm from walls, locomotor time 10.50.53.40.1-0.4-0.0-0.2-0.9-0.60.70.3-0.40.30.0-1.8
Bouts of movement, locomotor time 10.20.20.5-0.4-0.30.4-0.5-0.00.7-0.6-0.40.5-0.50.20.7
Total resting periods, locomotor time 10.10.20.5-0.30.10.0-0.30.30.3-0.5-0.20.5-0.50.40.7
Rest time, locomotor task time 10.40.41.00.80.7-0.80.70.4-1.00.8-0.2-0.70.5-0.3-0.5
Distance moved, locomotor task time 10.30.30.6-0.3-0.40.6-0.6-0.30.8-0.6-0.70.7-0.60.60.4
Vertical activity count, locomotor time 11.41.52.2-1.3-1.21.3-1.5-0.91.4-1.3-1.11.3-1.31.20.3
Time >=10cm from walls, locomotor time 20.20.20.7-0.6-0.60.4-0.3-0.80.4-0.30.10.10.1-0.0-0.8
Bouts of movement, locomotor time 22.42.56.0-2.1-1.81.9-1.7-1.82.4-1.4-1.71.1-0.80.5-0.5
Total resting periods, locomotor time 22.62.86.2-2.2-1.81.8-1.9-1.82.5-1.6-1.61.4-1.10.8-0.4
Rest time, locomotor task time 20.60.72.00.61.0-1.30.80.6-1.40.50.9-0.80.7-0.7-0.4
Distance moved, locomotor task time 20.80.92.6-0.5-0.81.2-0.9-0.51.4-0.7-1.60.9-0.80.90.6
Vertical activity count, locomotor time 24.14.46.9-2.0-2.32.6-2.3-1.82.6-1.9-2.62.1-2.01.70.4
Light reinforcement 10.50.92.70.51.6-1.40.81.7-0.70.10.40.0-0.10.41.2
Light reinforcement 20.91.23.0-0.70.30.1-0.80.80.4-1.2-1.11.3-1.61.61.7
Bone: marrow area0.61.33.6-0.4-1.51.2-0.9-1.90.80.1-1.1-0.50.6-1.0-1.9
Bone: maximum diameter2.24.07.4-1.7-2.42.4-2.7-2.32.6-2.0-2.11.6-1.21.1-0.6
Bone: maximum force0.40.71.3-0.8-1.00.9-1.1-1.11.1-0.8-0.70.4-0.10.4-0.6
Bone: maximum moment0.40.81.6-0.9-1.00.9-1.3-1.11.1-0.9-0.80.5-0.30.4-0.5
Mean time between licks in bursts0.10.20.60.4-0.50.60.2-0.3-0.10.7-0.2-0.40.4-0.7-0.2
Mean num. licks in bursts0.81.01.70.90.9-0.81.31.1-1.21.01.1-0.80.7-1.10.6
Cd content in liver0.10.20.50.20.1-0.10.70.2-0.70.60.3-0.30.1-0.4-0.0
Co content in liver0.91.12.21.11.2-1.21.20.9-1.41.50.0-1.21.1-0.6-0.2
Cu content in liver2.63.15.0-1.8-1.61.9-2.0-0.71.9-2.2-1.02.2-2.11.61.5
Fe content in liver9.110.916.3-3.5-3.23.7-3.6-2.03.6-4.0-2.03.9-3.93.01.9
K content in liver0.60.61.41.01.1-1.20.80.7-0.90.60.2-0.70.8-0.7-0.2
Mg content in liver1.61.62.31.41.4-1.51.51.1-1.50.91.0-1.51.4-1.40.0
Mn content in liver0.10.10.4-0.3-0.40.40.0-0.3-0.20.2-0.6-0.40.4-0.6-0.0
Na content in liver0.60.62.41.00.3-0.70.4-0.4-0.50.60.4-0.90.9-0.7-1.5
Rb content in liver1.92.37.90.71.7-1.51.62.3-1.20.12.80.0-0.10.02.2
Se content in liver1.41.75.8-1.1-0.30.3-1.20.00.7-1.7-0.11.9-2.02.41.0
Sr content in liver1.11.03.0-1.0-1.11.0-1.2-1.41.3-0.4-1.70.2-0.00.2-1.1
Zn content in liver2.62.94.6-2.0-2.12.0-2.1-2.21.4-1.7-1.91.3-1.30.9-0.8
Bone: minimum diameter0.10.10.40.0-0.00.1-0.60.00.3-0.6-0.10.4-0.20.10.3
Time in familiar zone, hab. session 10.30.30.6-0.7-0.50.5-0.6-0.40.4-0.3-0.70.6-0.70.8-0.2
Time in novel zone, hab. session 10.10.10.3-0.4-0.50.6-0.3-0.40.4-0.40.10.2-0.0-0.10.1
Total zone transitions, hab. session 12.63.79.51.10.6-1.11.4-0.4-1.32.30.5-2.83.1-3.0-2.5
Total locomotion distance, hab. session 11.21.73.91.10.8-1.01.30.4-1.01.51.2-1.72.0-1.8-0.7
Locomotion velocity, hab. session 11.92.64.41.71.5-1.71.81.1-1.51.81.6-1.92.1-1.8-0.4
Time in familiar zone, hab. session 21.11.12.9-1.4-0.50.7-0.50.30.6-1.30.61.4-1.31.11.7
Time in novel zone, hab. session 20.50.51.41.20.4-0.60.4-0.0-0.60.9-0.3-0.90.8-0.7-0.9
Total zone transitions, hab. session 21.31.66.11.0-0.40.2-0.0-1.0-0.51.9-1.7-1.31.5-1.0-2.5
Total locomotion distance, hab. session 21.11.44.11.70.3-0.50.7-0.1-1.12.0-0.6-1.51.5-1.0-1.6
Locomotion velocity, hab. session 21.21.64.51.70.2-0.40.7-0.3-1.12.1-0.7-1.61.6-1.1-1.8
Novel to familiar place preference ratio0.10.10.30.2-0.20.2-0.0-0.3-0.10.3-0.3-0.20.1-0.1-0.6
Novelty place preference0.10.10.30.0-0.30.3-0.1-0.40.00.2-0.2-0.1-0.0-0.0-0.5
Time in novel zone, NPP test0.10.10.3-0.2-0.50.4-0.2-0.60.10.1-0.3-0.1-0.1-0.0-0.6
Total zone transitions, NPP test0.60.92.60.1-0.60.5-0.3-1.10.30.8-1.5-0.91.1-1.1-1.6
Total locomotion distance, NPP test0.81.02.41.20.9-1.10.80.4-0.81.30.3-1.31.6-1.1-0.8
Locomotion velocity, NPP test1.11.53.71.50.9-1.11.00.4-0.81.60.3-1.61.9-1.5-1.1
Intraocular pressure0.20.30.6-0.6-0.70.8-0.6-0.40.3-0.80.30.6-0.50.30.4
Delta distance traveled before/after self-admin0.60.71.81.30.4-0.30.60.3-0.71.2-0.3-1.11.2-0.8-0.2
Delta ambulatory time before/after self-admin0.40.41.61.30.7-0.40.10.8-0.40.7-0.3-0.60.7-0.20.6
Parametrial fat weight1.01.94.9-1.8-1.81.4-1.2-2.21.4-0.8-1.20.4-0.40.1-1.8
Pavlov. Cond. lever latency3.24.18.1-2.5-2.92.7-2.2-2.51.6-1.9-1.41.7-1.90.9-0.7
Pavlov. Cond. magazine entry latency2.02.66.11.61.2-1.41.60.4-1.41.90.6-2.32.5-2.1-1.3
Pavlov. Cond. change in total contacts1.21.33.50.81.9-1.71.11.7-0.60.31.2-0.60.9-0.11.0
Pavlov. Cond. index score2.12.74.41.82.0-2.11.81.5-1.21.51.2-1.82.1-1.3-0.2
Pavlov. Cond. latency score2.53.24.92.22.2-2.22.01.6-1.41.81.1-2.02.2-1.3-0.3
Pavlov. Cond. lever contacts3.74.39.32.33.1-2.92.32.7-1.71.61.8-1.61.8-0.70.9
Pavlov. Cond. magazine entry number2.02.56.0-1.1-1.31.6-1.7-0.71.2-1.5-1.22.1-2.52.20.8
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.4-0.30.3-0.1-0.10.0-0.3-0.10.5-0.80.70.3
Pavlov. Cond. lever-magazine prob. diff.1.62.03.61.61.9-1.91.61.4-1.11.31.1-1.51.8-1.0-0.0
Pavlov. Cond. response bias1.82.23.91.41.8-1.91.71.3-1.21.31.2-1.72.0-1.4-0.1
Pavlov. Cond. lever latency0.30.40.8-0.6-0.80.9-0.7-0.70.5-0.3-0.90.5-0.60.4-0.2
Pavlov. Cond. magazine entry latency0.00.00.1-0.10.00.0-0.00.00.2-0.20.20.2-0.10.30.2
Pavlov. Cond. change in total contacts0.10.10.1-0.4-0.20.20.1-0.30.2-0.10.3-0.30.3-0.4-0.3
Pavlov. Cond. index score0.10.20.40.30.3-0.50.40.1-0.30.30.6-0.50.6-0.4-0.3
Pavlov. Cond. latency score0.10.20.40.30.3-0.40.40.1-0.40.20.6-0.50.5-0.4-0.2
Pavlov. Cond. lever contacts0.50.72.10.81.2-1.30.81.1-0.70.21.4-0.30.30.10.5
Pavlov. Cond. magazine entry number0.00.00.30.2-0.10.2-0.2-0.0-0.00.1-0.60.0-0.1-0.10.0
Pavlov. Cond. intertrial magazine entries0.91.23.31.00.4-0.70.9-0.1-1.11.30.4-1.51.4-1.8-1.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.30.3-0.40.30.1-0.20.20.5-0.40.5-0.3-0.2
Pavlov. Cond. response bias0.70.93.00.71.3-1.41.11.1-0.80.41.7-0.50.6-0.10.3
Time in closed arm before self-admin0.50.61.6-0.2-1.11.1-0.6-1.10.6-0.1-1.30.1-0.1-0.3-0.7
Time in closed arm after self-admin1.61.64.5-1.3-1.81.8-1.0-1.81.2-0.6-2.10.2-0.1-0.4-0.8
Time in open arm before self-admin0.91.02.0-1.3-1.41.4-1.1-1.31.2-0.7-0.80.5-0.50.1-0.3
Time in open arm after self-admin0.70.71.51.11.2-1.10.81.2-0.70.71.2-0.30.30.10.4
Bone: periosteal estimation1.22.54.9-1.4-2.11.9-2.1-2.22.0-1.2-1.60.9-0.50.2-1.2
Bone: periosteal perimeter1.42.44.6-1.8-1.61.6-2.2-1.62.0-2.0-1.01.4-1.00.9-0.1
Bone: post-yield work0.40.61.9-0.20.00.3-0.70.30.6-0.8-0.60.9-0.91.41.0
Progressive ratio test 1 active lever presses0.40.41.60.3-0.30.3-0.4-0.70.80.3-1.2-0.20.5-0.5-1.0
Progressive ratio test 1 breakpoint0.40.51.40.7-0.20.1-0.1-0.60.50.6-1.2-0.50.7-0.7-1.1
Progressive ratio test 1 inactive lever presses0.60.71.8-0.4-1.01.0-0.8-1.11.3-0.4-1.30.3-0.0-0.3-0.7
Progressive ratio test 2 active lever presses2.22.311.80.3-1.40.8-0.0-2.20.21.4-0.9-1.21.5-1.6-3.4
Progressive ratio test 2 breakpoint2.12.411.00.6-1.20.70.1-2.00.01.6-1.0-1.41.6-1.7-3.3
Progressive ratio test 2 inactive lever presses1.31.57.6-0.6-1.30.7-0.3-2.00.80.5-0.5-0.50.8-1.2-2.8
Incentive Sensitization - Responses2.22.312.5-0.1-1.40.60.1-2.2-0.31.3-0.1-1.31.4-1.5-3.5
Incentive Sensitization - Breakpoint2.22.212.2-0.0-1.30.50.2-2.1-0.41.4-0.0-1.31.4-1.5-3.5
Sum of active levers in priming session hrs 5-60.20.20.6-0.4-0.60.5-0.7-0.70.6-0.2-0.10.10.10.2-0.7
Progressive ratio0.60.72.40.30.6-0.90.6-0.1-0.40.70.3-1.11.2-1.5-1.3
Food seeking constrained by brief footshock0.91.13.1-1.4-1.21.4-0.7-0.80.9-0.7-1.80.9-1.10.70.3
Seeking ratio, punishment vs. effort1.31.63.5-1.0-1.51.9-1.0-0.91.0-0.7-1.71.2-1.41.50.7
Retroperitoneal fat weight2.16.715.0-3.0-1.21.2-2.7-0.73.1-3.90.23.6-3.13.41.5
Reaction time number correct0.71.12.9-1.0-1.41.1-1.0-1.70.4-0.1-1.3-0.00.0-0.5-1.7
Reaction time mean minus median4.55.99.42.62.5-2.62.71.9-1.92.22.7-2.73.1-2.8-0.0
Reaction time mean minus median AUC5.47.110.52.82.5-2.73.01.9-2.42.43.1-3.03.2-3.0-0.2
Reaction time num false alarms0.10.10.50.30.4-0.40.10.1-0.70.1-0.6-0.20.20.0-0.3
Reaction time num false alarms AUC0.10.10.3-0.20.4-0.4-0.20.3-0.4-0.5-0.40.3-0.30.40.3
Reaction time trials correct on left0.71.12.9-1.0-1.41.1-1.0-1.70.4-0.1-1.3-0.00.0-0.5-1.7
Reaction time trials on left0.71.02.8-1.0-1.31.0-0.9-1.60.3-0.0-1.2-0.10.1-0.6-1.7
Reaction time mean3.65.09.12.62.9-2.72.43.0-2.31.73.0-1.31.3-0.31.6
Reaction time mean AUC3.44.58.62.42.7-2.52.32.9-2.11.62.9-1.21.2-0.21.7
Median of all reaction times2.73.78.82.12.6-2.21.83.0-2.01.12.5-0.40.20.82.1
Reaction time omissions1.31.82.51.61.4-1.41.31.5-1.41.41.5-1.31.3-1.30.5
Reaction time false alarm rate0.20.31.00.00.7-0.60.00.7-0.2-0.70.10.4-0.40.81.0
Reaction time premature initiation rate8.010.715.03.93.3-3.63.82.4-3.63.52.4-3.73.7-3.3-0.9
Reaction time premature initiations5.67.912.13.22.3-2.73.01.3-3.13.31.5-3.53.5-3.5-1.7
Std. dev. reaction times3.95.59.92.52.7-2.72.62.2-2.02.03.1-2.32.6-2.00.4
Reaction time trials completed0.71.02.8-1.0-1.31.0-0.9-1.60.3-0.0-1.2-0.10.1-0.6-1.7
Reaction time trials AUC0.71.02.4-1.1-1.31.0-1.0-1.60.4-0.2-1.20.1-0.1-0.4-1.5
Run reversals in cocaine runway, females0.20.20.90.90.2-0.10.30.3-0.30.70.0-0.30.2-0.10.1
Run reversals in cocaine runway, males1.91.93.4-1.4-1.31.6-1.8-0.91.7-1.3-1.71.3-1.31.00.6
Latency to leave start box in cocaine runway0.70.82.6-1.00.6-0.50.80.8-0.3-1.11.60.4-0.5-0.21.5
Latency to leave start box in cocaine runway, F1.11.23.6-1.7-0.40.5-0.50.10.9-1.90.91.4-1.40.41.5
Latency to leave start box in cocaine runway, M1.61.53.40.71.1-1.21.80.8-1.81.20.9-1.61.3-1.1-0.0
Std. dev. time between licks in bursts0.10.10.90.1-0.2-0.10.0-0.6-0.00.20.1-0.40.4-0.3-1.0
Total sessions with >9 infusions0.50.62.30.2-0.91.0-0.5-0.81.5-0.3-1.10.3-0.0-0.7-0.3
Short access day 1 total inactive lever presses1.21.33.1-1.2-1.51.3-0.9-1.81.4-0.5-1.10.00.3-0.9-1.3
Short access day 10 total inactive lever presses0.50.61.60.10.7-0.91.00.5-0.80.51.3-0.70.8-0.9-0.2
Short access day 1 total infusions0.80.82.4-0.1-0.91.0-0.9-0.71.5-0.5-1.50.9-0.70.5-0.1
Short access day 10 total infusions0.40.51.71.20.1-0.10.1-0.20.30.7-1.3-0.50.7-0.7-0.8
Short access total infusions0.20.31.10.8-0.20.2-0.1-0.40.60.4-1.10.00.1-0.1-0.8
Short access day 1 locomotion0.20.21.60.3-0.10.3-0.20.00.6-0.1-1.30.3-0.30.30.3
Short access day 10 total locomotion0.60.61.5-0.5-0.60.8-0.9-0.31.2-0.8-1.10.9-0.80.50.5
Short access total locomotion0.30.30.70.90.6-0.40.60.7-0.10.4-0.3-0.30.4-0.70.6
One hour access (0.3 mA shock)1.11.33.51.90.3-0.51.0-0.1-0.61.7-0.2-1.21.4-1.3-1.5
Compulsive drug intake0.50.51.00.80.7-0.50.71.0-0.90.50.8-0.40.2-0.10.9
One hour access (shock baseline)0.50.62.61.00.1-0.40.5-0.40.01.0-0.3-0.71.0-0.9-1.6
Social response proportion0.70.72.80.1-1.01.0-0.1-1.00.60.5-0.5-0.71.0-1.7-0.8
Social responses1.82.38.01.50.9-0.91.70.5-0.71.21.1-2.12.3-2.8-0.4
Social time0.50.62.00.61.1-0.90.41.40.2-0.11.00.4-0.10.11.4
Soleus weight0.72.15.2-1.9-1.21.4-1.7-1.02.3-2.0-1.01.5-1.11.00.6
Bone: stiffness0.10.10.6-0.10.0-0.3-0.1-0.50.1-0.30.2-0.30.6-0.1-0.8
Tibialis anterior weight1.55.19.5-2.9-3.13.0-2.6-3.02.5-1.6-2.31.1-0.70.3-1.3
Time to tail flick, vehicle, before self-admin0.40.41.10.40.7-0.60.81.0-0.6-0.01.00.00.00.51.0
Time to tail flick, vehicle, after self-admin0.20.30.6-0.50.4-0.70.8-0.0-0.3-0.20.8-0.40.5-0.5-0.5
Time to tail flick, test, before self-admin0.70.71.4-0.8-0.90.7-1.2-1.10.9-0.8-1.00.4-0.20.2-0.8
Time to tail flick, test, after self-admin0.20.20.4-0.30.5-0.60.30.6-0.6-0.00.70.1-0.1-0.10.3
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.50.3-0.50.20.1-0.1-0.30.50.2-0.30.1-0.3
Delta time to tail flick, test, before/after SA0.80.81.40.51.1-1.11.11.1-1.20.71.1-0.50.3-0.50.5
Tibia length1.23.59.0-2.5-2.62.2-2.0-3.02.0-1.3-1.10.5-0.2-0.4-2.0
Ambulatory time before self-admin0.30.31.2-0.40.6-0.40.30.8-0.2-0.60.10.5-0.60.61.1
Ambulatory time after self-admin0.40.52.00.80.8-0.5-0.11.1-0.1-0.2-0.30.2-0.20.71.4
Bone: tissue strength1.41.42.6-1.6-1.51.5-1.4-1.30.8-0.9-1.10.9-1.11.0-0.3
Total heroin consumption1.31.53.81.51.9-1.70.72.0-0.80.11.3-0.10.10.21.6
Bone: trabecular number4.06.310.1-2.7-3.13.1-3.2-2.73.0-2.1-2.22.2-2.01.9-0.7
Bone: trabecular spacing0.81.02.00.61.3-1.41.31.2-1.40.41.4-0.50.4-0.20.4
Bone: trabecular thickness5.46.510.4-2.6-2.82.8-3.2-2.43.2-2.4-2.22.7-2.52.3-0.4
Bone: trabecular tissue density0.30.41.6-1.00.3-0.60.1-0.2-0.3-0.91.30.1-0.10.2-0.3
Water consumed over 24 hours0.50.62.90.3-0.40.1-0.1-0.90.00.7-0.7-0.81.0-1.0-1.7
Number of responses in last shaping day0.60.63.20.20.20.3-0.10.80.9-0.5-0.80.7-0.60.51.8