Cep83os

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Cep83os 0.15 0.06 2.1e-15 0.1 0.12 0.12 0.12 2.9e-11 1.8e-13 1.2e-13 1.3e-13
2 LHb gene expression Cep83os 0.4 0.15 7.8e-03 0.02 -0.01 0.01 0.05 1.2e-01 8.1e-01 2.0e-01 2.8e-02
3 OFC gene expression Cep83os 0.54 0.12 2.7e-05 0.16 0.22 0.26 0.26 1.6e-04 7.6e-06 7.9e-07 8.8e-07
4 Brain gene expression Cep83os 0.39 0.09 0.0e+00 0.09 0.22 0.26 0.26 1.7e-08 2.1e-20 2.6e-24 5.2e-24
5 BLA gene expression Cep83os 0.61 0.11 7.8e-16 0.1 0.25 0.24 0.24 8.2e-06 1.0e-13 5.2e-13 5.4e-13
6 Adipose mRNA stability Cep83os 0.08 0.04 1.2e-03 0.04 0.01 0.03 0.03 9.5e-06 1.3e-02 6.9e-04 2.8e-04
7 IL gene expression Cep83os 0.78 0.07 1.6e-08 0.18 0.21 0.27 0.26 5.3e-05 9.2e-06 3.3e-07 5.8e-07
8 PL gene expression Cep83os 0.5 0.09 0.0e+00 0.18 0.3 0.32 0.32 4.0e-19 2.1e-33 1.8e-35 2.8e-36
9 NAcc gene expression Cep83os 0.69 0.05 3.2e-12 0.13 0.12 0.11 0.12 8.0e-15 2.9e-13 7.9e-13 7.0e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.51.1-0.2-0.50.50.5-0.90.91.0-1.00.7
Area under the delay curve7.27.611.10.5-3.32.73.1-3.02.92.7-2.72.9
BMI with tail0.41.48.8-3.0-1.4-0.00.30.5-0.6-0.00.6-0.8
BMI without tail0.51.07.4-2.7-0.6-0.3-0.30.90.3-0.20.20.1
Body weight1.35.642.4-6.5-0.9-1.2-1.21.40.9-0.80.20.6
Weight adjusted by age0.30.40.6-0.30.8-0.5-0.80.5-0.6-0.70.6-0.6
Bone surface0.81.32.2-0.6-1.51.01.1-0.91.41.3-1.31.1
Bone volume0.81.42.0-0.6-1.30.91.0-1.11.41.4-1.41.2
Breakpoint value in progressive ratio session0.50.51.10.9-0.70.61.0-0.7-0.11.1-0.3-0.1
Number of licking bursts0.20.20.8-0.9-0.1-0.4-0.20.6-0.50.00.4-0.5
Context. condit. distance diff. score0.20.21.3-1.2-0.40.1-0.0-0.00.1-0.70.2-0.1
Locomotion velocity, session 10.20.20.50.60.5-0.1-0.5-0.2-0.7-0.10.5-0.6
Locomotion distance, session 10.10.20.5-0.6-0.0-0.4-0.30.3-0.5-0.20.3-0.7
Locomotion velocity, session 20.20.20.70.40.8-0.5-0.50.1-0.3-0.60.1-0.7
Locomotion distance, session 20.10.10.6-0.8-0.2-0.20.10.20.00.1-0.1-0.2
Locomotion velocity, session 30.20.20.90.6-0.10.7-0.0-0.90.10.1-0.30.0
Locomotion distance, session 30.10.10.3-0.6-0.40.50.2-0.1-0.20.10.2-0.0
Stereotopy head waving bouts, day 30.30.32.01.40.40.10.0-0.30.20.7-0.40.3
Stereotopy head waving duration, day 30.30.41.11.00.10.40.1-1.00.50.6-0.80.5
Locomotion velocity, session 72.83.04.7-1.31.4-1.4-1.31.6-2.1-1.92.2-2.0
Locomotion distance, session 70.30.30.8-0.60.4-0.1-0.20.4-0.9-0.60.9-0.5
Stereotopy head waving bouts, day 70.91.02.1-0.11.2-0.9-1.40.6-1.0-1.00.8-1.4
Stereotopy head waving duration, day 70.10.20.70.30.4-0.2-0.60.0-0.4-0.20.1-0.9
Locomotion velocity, session 80.10.10.3-0.10.4-0.2-0.3-0.20.6-0.3-0.40.2
Locomotion distance, session 80.50.75.2-2.3-0.4-0.3-0.20.40.1-0.80.3-0.3
Degree of sensitization distance0.10.10.30.3-0.10.40.4-0.40.10.3-0.20.5
Degree of sensitization stereotypy0.91.02.7-0.00.9-0.6-1.00.4-1.3-1.01.0-1.7
Conditioned locomotion0.30.30.7-0.50.1-0.7-0.30.4-0.7-0.80.8-0.5
Cocaine response after cond. corrected3.94.37.80.3-1.71.71.9-2.02.82.1-2.52.6
Cocaine response after cond. not corrected3.94.37.80.3-1.71.71.8-1.92.82.1-2.52.8
Cocaine response before conditioning0.20.20.50.30.4-0.4-0.70.7-0.5-0.30.5-0.2
Saline control response0.20.20.5-0.70.5-0.3-0.70.1-0.3-0.60.30.3
Bone: connectivity density0.30.51.10.7-0.00.40.3-0.60.91.0-1.10.7
Bone: cortical apparent density2.02.73.8-1.21.0-1.8-1.41.8-1.7-1.82.0-1.7
Bone: cortical area2.53.87.2-0.6-1.81.21.7-1.52.72.0-2.42.7
Bone: cortical porosity2.83.15.31.2-0.91.71.3-1.82.31.6-2.32.1
Bone: cortical porosity2.93.15.30.8-1.31.71.4-1.72.31.8-2.22.2
Bone: cortical thickness2.23.58.20.2-0.91.11.3-1.62.91.8-2.62.7
Bone: cortical thickness1.51.82.61.5-0.71.21.2-1.21.31.6-1.51.6
Bone: cortical tissue density2.22.94.3-1.21.0-1.9-1.51.9-1.8-1.92.1-1.8
Condit. Reinf. active minus inactive responses0.60.61.61.30.4-0.5-0.50.8-1.0-0.40.8-1.1
Condit. Reinf. active-inactive response ratio0.20.21.21.1-0.40.40.3-0.1-0.10.2-0.1-0.4
Condit. Reinf. active responses0.70.83.71.90.7-0.6-0.40.7-1.0-0.10.7-0.8
Condit. Reinf. inactive responses0.40.42.61.60.6-0.4-0.00.3-0.70.20.4-0.2
Incentive salience index mean0.50.71.10.70.8-1.0-0.81.0-0.8-0.40.7-0.8
Condit. Reinf. lever presses0.40.51.2-0.00.8-1.1-0.71.0-0.7-0.30.7-0.3
Condit. Reinf. active minus inactive responses1.21.53.20.21.3-0.8-0.90.9-1.8-1.11.4-1.7
Condit. Reinf. active-inactive response ratio0.10.10.50.30.70.1-0.2-0.4-0.1-0.0-0.1-0.3
Condit. Reinf. active responses1.72.45.3-0.11.2-1.1-1.11.6-2.3-1.42.0-2.0
Condit. Reinf. inactive responses0.81.02.40.5-0.0-0.6-0.31.3-1.5-0.71.4-1.1
Condit. Reinf. lever presses2.23.05.5-0.61.6-1.5-1.41.7-2.3-1.62.0-2.2
Condit. Reinf. lever reinforcers received2.33.27.1-0.41.2-1.3-1.21.8-2.7-1.62.3-2.3
Conditioned reinforcement - actives0.50.51.1-1.00.9-0.8-1.10.6-0.0-0.50.3-0.0
Conditioned reinforcement - inactives0.30.30.8-0.40.5-0.9-0.80.9-0.0-0.20.1-0.0
Conditioned locomotion0.50.51.3-1.01.1-0.8-1.10.6-0.0-0.60.3-0.0
Patch foraging indifference point 0 sec0.00.10.30.1-0.20.20.2-0.00.30.2-0.20.5
Patch foraging indifference point AUC0.10.20.4-0.10.3-0.3-0.30.10.60.5-0.70.4
Delay disc. indifference point, 0s delay0.10.10.5-0.2-0.60.20.4-0.3-0.10.7-0.1-0.1
Delay disc. indifference point, 16s delay7.47.513.6-0.2-3.72.73.3-2.82.62.8-2.52.6
Delay disc. indifference point, 2s delay0.30.30.5-0.6-0.70.20.5-0.70.60.3-0.50.6
Delay disc. indifference point, 24s delay7.26.99.30.4-3.02.42.6-2.73.02.6-2.83.0
Delay disc. indifference point, 4s delay2.72.84.00.5-1.61.61.5-1.82.01.6-1.82.0
Delay disc. indifference point, 8s delay10.611.014.21.4-3.83.53.6-3.63.43.3-3.33.4
Indifference point function ln k0.10.10.2-0.1-0.50.30.50.1-0.2-0.10.30.0
Indifference point function log k0.10.10.2-0.1-0.50.30.50.1-0.2-0.10.30.0
Patch foraging total patch changes 0 sec0.10.10.30.2-0.30.30.2-0.10.30.3-0.20.6
Patch foraging total patch changes 12 sec0.30.40.9-0.50.9-0.7-0.70.40.50.1-0.40.6
Patch foraging total patch changes 18 sec1.82.34.1-1.21.8-2.0-1.91.7-1.0-1.61.2-1.0
Patch foraging total patch changes 24 sec0.30.41.0-0.81.0-0.8-0.90.30.3-0.5-0.10.3
Patch foraging total patch changes 6 sec0.00.00.1-0.1-0.1-0.3-0.00.30.10.2-0.20.2
Patch foraging time to switch 0 sec0.40.51.2-0.20.6-0.9-0.60.6-0.7-1.10.8-0.7
Patch foraging water rate 0 sec0.30.54.1-2.0-0.60.0-0.00.60.20.20.10.1
Patch foraging water rate 12 sec0.40.64.0-2.00.8-0.5-0.70.3-0.0-0.40.20.1
Patch foraging water rate 18 sec0.20.30.7-0.8-0.20.40.1-0.2-0.8-0.10.5-0.8
Patch foraging water rate 24 sec1.11.59.2-3.0-0.1-1.0-0.60.8-0.6-1.01.1-0.5
Patch foraging water rate 6 sec2.13.113.7-3.70.6-1.4-1.21.6-1.3-1.41.7-1.1
Seeking ratio, delayed vs. immediate footshock0.70.81.50.7-0.50.30.8-0.61.21.2-1.21.2
Distance traveled before self-admin0.00.00.1-0.3-0.1-0.10.1-0.10.10.1-0.10.1
Distance traveled after self-admin0.20.20.7-0.5-0.9-0.10.6-0.20.10.5-0.20.1
Extensor digitorum longus weight1.03.85.4-0.3-2.32.02.0-1.82.12.1-2.12.1
Bone: elastic displacement4.65.210.73.3-1.22.32.0-2.32.12.3-2.42.0
Bone: elastic work6.38.210.83.2-1.82.72.5-2.83.13.0-3.33.0
Bone: endosteal estimation0.71.56.7-1.1-2.61.41.7-0.5-0.30.80.10.0
Bone: endosteal perimeter0.81.64.7-2.0-2.20.51.4-0.20.90.8-0.51.1
Epididymis fat weight2.55.812.0-3.51.1-2.0-2.02.4-2.5-2.32.7-2.6
Delta time in closed arm before/after self-admin0.10.10.4-0.7-0.30.20.1-0.30.10.1-0.20.1
Delta time in open arm before/after self-admin0.50.53.21.8-0.10.50.7-0.50.10.5-0.30.1
Diff in mean of infusions in LGA sessions0.20.31.01.0-0.10.50.4-0.8-0.00.4-0.3-0.0
Delay discount exponential model param7.17.510.4-0.53.2-2.6-3.02.9-3.0-2.62.8-3.0
Extinction: sum of active levers before priming0.20.20.90.4-0.50.90.4-0.60.00.6-0.20.0
Active lever presses in extinction session 60.30.30.7-0.4-0.80.50.7-0.6-0.10.5-0.1-0.1
Bone: final force2.54.05.4-0.4-2.32.02.2-2.02.02.2-2.02.1
Bone: final moment3.15.16.4-0.2-2.42.22.3-2.32.42.5-2.42.5
Food consumed during 24 hour testing period1.51.83.0-1.11.4-1.7-1.41.3-1.2-1.51.3-1.2
Glucose0.20.30.5-0.60.6-0.7-0.50.4-0.6-0.50.5-0.6
Heart weight4.15.97.91.0-2.72.62.6-2.32.42.8-2.62.2
Delay discount hyperbolic model param6.67.09.3-0.43.1-2.5-2.82.8-2.9-2.52.7-2.9
Intermittent access intake day 1-15 change0.80.81.8-0.61.3-1.1-1.31.2-0.2-0.60.3-0.2
Intermittent access intake escalation0.90.92.2-0.51.4-1.2-1.51.3-0.2-0.60.3-0.2
Intermittent access intake escalation 20.20.20.60.10.7-0.4-0.80.6-0.1-0.40.2-0.1
Intermitt. access day 1 inactive lever presses0.30.42.51.60.10.30.3-0.40.10.4-0.40.1
Intermitt. access day 15 inactive lever presses0.30.31.61.3-0.30.50.3-0.5-0.10.3-0.3-0.1
Intermitt. access escalation Index0.20.21.01.00.20.40.1-0.2-0.3-0.00.1-0.3
Intermittent access day 1 total infusions0.50.62.9-1.70.5-0.6-0.80.3-0.0-1.00.5-0.0
Intermittent access day 15 total infusions1.01.23.6-1.91.0-1.1-1.41.0-0.1-1.10.5-0.1
Intermittent access terminal intake (last 3 days)0.80.93.2-1.80.7-0.9-1.20.9-0.1-1.10.6-0.1
Intermittent access total infusions0.91.04.4-2.10.6-0.9-1.00.8-0.1-1.10.6-0.1
Intermittent access day 1 locomotion0.30.31.6-1.30.3-0.3-0.60.1-0.0-0.70.3-0.0
Intermittent access day 15 total locomotion1.71.84.4-1.21.9-1.6-2.11.4-0.2-1.30.6-0.2
Intermittent access total locomotion0.80.92.8-1.70.9-1.0-1.20.7-0.1-1.10.5-0.1
Intermittent access standard deviation1.11.22.6-1.61.2-1.3-1.51.3-0.0-1.00.4-0.0
Left kidney weight0.41.05.6-2.40.2-1.1-1.20.90.4-0.2-0.10.3
Right kidney weight0.20.64.0-2.0-0.6-0.3-0.30.40.50.2-0.30.4
Cocaine induced anxiety0.80.92.51.6-1.11.11.3-1.10.10.5-0.40.1
Post-drug Anxiety0.60.72.61.6-0.51.10.7-1.20.10.2-0.30.1
Baseline Anxiety0.40.41.4-0.51.2-0.6-1.10.3-0.2-0.60.3-0.2
Tail length1.13.214.2-3.81.0-1.6-2.01.61.2-1.30.01.1
Length with tail1.65.829.4-5.41.1-2.3-2.72.01.0-1.90.40.9
Length without tail0.61.37.4-2.70.1-0.7-1.00.21.0-0.3-0.41.0
Times rat made contact with spout1.21.44.0-2.01.3-1.7-1.51.10.0-0.60.20.0
Lifetime Intake0.70.73.9-2.00.2-0.7-0.70.6-0.1-1.00.6-0.1
Liver weight, left0.30.51.8-1.30.2-0.9-0.30.6-0.5-0.80.6-0.5
Liver weight, right0.81.31.9-1.41.0-1.3-1.01.2-1.0-1.11.1-1.1
Locomotor activity0.50.97.0-2.6-0.5-0.1-0.40.60.2-0.10.10.1
Locomotor testing distance0.40.64.4-2.1-1.0-0.10.20.30.00.00.20.2
Locomotor testing rearing0.40.61.8-0.4-0.90.50.3-0.21.00.7-0.71.3
Locomotion in novel chamber0.00.10.30.3-0.50.20.20.2-0.1-0.10.2-0.1
Locomotion in novel chamber post-restriction0.10.10.3-0.50.1-0.2-0.4-0.00.3-0.3-0.10.0
Fecal boli incidents, locomotor time 10.10.10.30.10.1-0.5-0.10.5-0.2-0.40.4-0.2
Change in fecal boli incidents, locomotor task0.40.41.1-0.1-0.30.40.1-0.1-1.1-0.70.9-1.1
Time >=10cm from walls, locomotor time 11.11.22.20.9-1.51.51.4-1.20.51.0-0.70.5
Bouts of movement, locomotor time 12.52.74.71.2-1.81.61.7-1.31.52.2-1.71.5
Total resting periods, locomotor time 11.92.13.91.4-1.51.61.3-1.11.22.0-1.51.2
Rest time, locomotor task time 10.60.62.21.5-0.61.00.4-0.70.31.0-0.60.3
Distance moved, locomotor task time 11.81.94.3-1.11.6-2.1-1.21.7-0.9-1.51.1-0.9
Vertical activity count, locomotor time 12.02.14.8-2.21.0-2.1-1.01.5-0.9-1.51.3-0.9
Time >=10cm from walls, locomotor time 20.10.10.60.70.60.0-0.40.1-0.10.1-0.0-0.1
Bouts of movement, locomotor time 22.22.33.30.4-1.81.71.4-1.41.71.5-1.61.7
Total resting periods, locomotor time 22.62.74.40.5-2.11.91.6-1.61.71.7-1.61.7
Rest time, locomotor task time 20.70.82.40.4-1.51.31.1-1.1-0.00.8-0.3-0.0
Distance moved, locomotor task time 21.82.15.0-0.52.2-2.1-1.71.6-0.9-1.21.0-0.9
Vertical activity count, locomotor time 22.12.35.3-2.11.9-2.3-1.51.5-0.5-1.20.8-0.5
Light reinforcement 11.32.44.6-1.11.2-1.2-1.41.4-1.9-1.41.7-2.1
Light reinforcement 20.20.31.00.3-0.10.30.30.1-0.9-0.30.6-1.0
Bone: marrow area0.71.56.4-1.1-2.51.31.7-0.4-0.30.80.2-0.0
Bone: maximum diameter0.61.14.3-2.1-1.60.20.9-0.20.80.6-0.50.9
Bone: maximum force2.95.06.30.3-2.52.42.4-2.22.32.5-2.32.3
Bone: maximum moment3.66.38.00.6-2.62.62.6-2.52.72.8-2.82.7
Mean time between licks in bursts0.40.51.1-0.1-1.10.40.7-0.50.90.7-0.70.9
Mean num. licks in bursts0.20.20.6-0.10.8-0.6-0.60.10.2-0.4-0.10.2
Cd content in liver0.30.31.0-0.7-1.00.60.8-0.40.20.5-0.20.2
Co content in liver1.41.62.9-1.61.5-1.7-1.51.3-0.3-1.30.8-0.3
Cu content in liver0.50.61.9-1.40.8-0.9-0.70.8-0.4-0.60.5-0.4
Fe content in liver0.40.51.2-0.8-1.10.80.9-0.80.40.2-0.30.4
K content in liver2.42.35.30.22.3-1.9-1.91.8-0.9-1.41.1-0.9
Mg content in liver1.41.42.50.11.2-1.2-1.31.6-1.2-1.11.2-1.2
Mn content in liver0.60.71.7-0.30.7-0.9-0.71.3-0.8-0.80.9-0.8
Na content in liver1.11.22.3-0.31.5-1.3-1.21.0-0.9-1.21.1-0.9
Rb content in liver0.50.62.01.40.10.40.4-0.61.00.5-0.91.0
Se content in liver4.25.18.7-1.61.1-1.7-1.52.1-3.0-2.52.9-3.0
Sr content in liver1.61.52.70.5-0.40.80.8-1.41.51.5-1.71.5
Zn content in liver0.10.10.4-0.40.3-0.4-0.60.5-0.1-0.40.2-0.1
Bone: minimum diameter0.91.76.0-2.4-1.80.61.1-0.41.20.9-0.81.3
Time in familiar zone, hab. session 10.20.21.20.10.2-0.3-0.10.4-0.4-0.40.3-1.1
Time in novel zone, hab. session 10.70.71.60.6-1.01.31.0-1.00.20.6-0.20.9
Total zone transitions, hab. session 10.91.24.4-2.10.7-1.4-1.01.2-0.5-0.80.6-0.8
Total locomotion distance, hab. session 12.23.16.1-2.51.1-2.1-1.91.6-1.4-1.51.4-1.8
Locomotion velocity, hab. session 12.94.17.3-2.71.5-2.6-2.32.1-1.4-1.71.5-1.9
Time in familiar zone, hab. session 20.10.10.30.50.00.40.2-0.3-0.10.30.00.3
Time in novel zone, hab. session 20.50.51.40.3-1.20.80.9-0.70.50.6-0.60.2
Total zone transitions, hab. session 20.20.20.6-0.8-0.6-0.20.10.5-0.30.10.3-0.5
Total locomotion distance, hab. session 20.60.81.7-1.3-0.2-0.8-0.61.1-0.9-0.40.9-1.1
Locomotion velocity, hab. session 20.71.01.9-1.4-0.1-1.0-0.71.4-1.0-0.51.0-1.2
Novel to familiar place preference ratio1.71.74.10.52.0-1.5-1.61.3-1.0-1.31.1-1.0
Novelty place preference1.51.64.00.82.0-1.3-1.51.1-0.9-1.10.9-0.9
Time in novel zone, NPP test1.21.23.10.71.7-1.1-1.31.0-0.8-1.00.9-0.8
Total zone transitions, NPP test0.30.40.9-0.7-0.90.40.8-0.20.70.7-0.60.7
Total locomotion distance, NPP test0.60.82.1-1.40.3-1.1-0.71.1-0.8-0.60.8-0.7
Locomotion velocity, NPP test0.81.11.8-1.30.5-1.3-1.01.3-1.0-0.81.1-0.9
Intraocular pressure0.10.21.31.20.20.30.3-0.20.00.4-0.20.0
Delta distance traveled before/after self-admin0.10.10.1-0.3-0.4-0.20.30.10.10.3-0.10.1
Delta ambulatory time before/after self-admin0.20.20.60.3-0.80.10.7-0.30.00.5-0.20.0
Parametrial fat weight0.20.51.7-0.1-1.30.31.1-0.2-0.60.20.4-0.8
Pavlov. Cond. lever latency0.50.61.6-0.8-1.31.01.0-0.70.20.3-0.10.5
Pavlov. Cond. magazine entry latency0.81.02.20.00.6-1.1-0.71.2-1.3-0.71.2-1.5
Pavlov. Cond. change in total contacts1.51.62.6-0.51.1-1.4-1.11.5-1.4-1.11.3-1.6
Pavlov. Cond. index score0.50.61.20.40.9-1.1-0.80.9-0.8-0.40.6-1.0
Pavlov. Cond. latency score0.50.61.30.41.0-1.1-0.90.9-0.7-0.30.5-0.9
Pavlov. Cond. lever contacts0.60.82.10.11.5-1.3-1.20.9-0.3-0.50.3-0.5
Pavlov. Cond. magazine entry number0.81.01.90.2-0.41.00.7-1.11.30.8-1.31.4
Pavlov. Cond. intertrial magazine entries0.70.93.8-0.4-1.91.21.3-0.60.40.3-0.40.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.70.40.5-0.9-0.50.7-0.6-0.10.4-0.8
Pavlov. Cond. response bias1.51.92.9-0.31.2-1.7-1.41.6-1.4-1.21.4-1.6
Pavlov. Cond. lever latency1.62.24.90.6-0.80.91.0-1.42.21.4-2.02.0
Pavlov. Cond. magazine entry latency1.11.31.9-0.81.1-1.1-1.31.1-1.0-1.41.2-1.1
Pavlov. Cond. change in total contacts1.62.24.2-2.00.3-1.2-0.91.7-1.5-1.51.8-1.4
Pavlov. Cond. index score2.93.75.5-1.71.2-1.7-1.62.0-2.2-2.12.4-2.2
Pavlov. Cond. latency score3.13.85.7-1.51.3-1.8-1.62.1-2.2-2.22.4-2.3
Pavlov. Cond. lever contacts1.52.04.6-1.30.3-0.7-0.71.3-2.1-1.21.9-2.0
Pavlov. Cond. magazine entry number3.84.66.61.9-1.22.01.8-2.22.42.3-2.62.5
Pavlov. Cond. intertrial magazine entries0.60.81.21.1-0.20.90.7-0.81.01.0-1.11.1
Pavlov. Cond. lever-magazine prob. diff.2.93.65.0-1.81.3-1.8-1.72.0-2.0-2.12.2-2.0
Pavlov. Cond. response bias1.41.93.6-1.50.4-0.8-0.91.3-1.9-1.31.8-1.8
Time in closed arm before self-admin0.10.10.3-0.30.20.0-0.60.5-0.0-0.20.1-0.0
Time in closed arm after self-admin0.10.10.3-0.5-0.40.40.2-0.40.10.2-0.20.1
Time in open arm before self-admin0.00.00.0-0.2-0.2-0.10.10.1-0.10.10.1-0.1
Time in open arm after self-admin0.20.21.31.2-0.00.20.4-0.10.10.2-0.10.1
Bone: periosteal estimation1.42.87.8-1.2-2.81.62.1-1.21.31.5-1.21.5
Bone: periosteal perimeter1.52.44.8-1.2-2.21.01.8-1.01.71.5-1.51.9
Bone: post-yield work0.10.20.5-0.7-0.40.60.2-0.6-0.00.0-0.1-0.1
Progressive ratio test 1 active lever presses1.81.910.2-3.20.9-1.2-1.40.7-0.0-1.30.6-0.0
Progressive ratio test 1 breakpoint1.61.79.7-3.10.8-1.1-1.30.6-0.0-1.20.5-0.0
Progressive ratio test 1 inactive lever presses0.10.10.3-0.50.3-0.5-0.40.1-0.0-0.2-0.0-0.0
Progressive ratio test 2 active lever presses1.11.23.3-1.81.0-1.1-1.50.9-0.2-1.20.6-0.2
Progressive ratio test 2 breakpoint1.31.54.9-2.21.1-1.2-1.61.1-0.2-1.30.7-0.2
Progressive ratio test 2 inactive lever presses0.20.20.6-0.70.7-0.4-0.7-0.0-0.1-0.50.1-0.1
Incentive Sensitization - Responses1.21.22.5-1.11.3-1.3-1.61.4-0.1-1.10.5-0.1
Incentive Sensitization - Breakpoint1.11.12.4-1.01.4-1.2-1.51.3-0.1-1.10.5-0.1
Sum of active levers in priming session hrs 5-60.10.10.4-0.40.6-0.6-0.40.3-0.30.10.2-0.3
Progressive ratio0.50.62.71.6-1.00.80.8-0.40.50.1-0.40.2
Food seeking constrained by brief footshock0.40.51.1-0.90.9-0.8-1.00.5-0.0-1.00.40.1
Seeking ratio, punishment vs. effort0.50.62.2-1.51.1-0.8-0.90.4-0.3-0.40.4-0.1
Retroperitoneal fat weight1.65.410.4-3.20.8-2.5-1.92.6-2.1-2.32.5-2.2
Reaction time number correct0.30.50.90.1-0.90.90.7-1.00.40.8-0.60.3
Reaction time mean minus median1.31.74.52.1-0.61.30.8-1.11.21.5-1.41.3
Reaction time mean minus median AUC0.91.14.42.1-0.10.90.3-0.80.91.1-1.10.9
Reaction time num false alarms0.60.81.81.3-0.20.80.7-0.90.80.9-1.00.8
Reaction time num false alarms AUC1.01.42.51.6-0.61.31.1-1.31.01.3-1.31.0
Reaction time trials correct on left0.30.50.90.1-0.90.90.7-1.00.40.8-0.60.3
Reaction time trials on left0.40.61.10.2-1.01.00.8-1.00.40.9-0.60.4
Reaction time mean0.30.41.3-0.0-1.10.50.7-0.50.60.6-0.50.6
Reaction time mean AUC0.40.51.0-0.0-1.00.50.6-0.60.80.6-0.80.9
Median of all reaction times0.20.31.3-1.1-1.00.00.3-0.1-0.0-0.10.10.0
Reaction time omissions1.72.34.32.1-1.51.71.8-1.70.91.6-1.20.6
Reaction time false alarm rate0.30.41.51.20.00.50.5-0.50.40.5-0.50.5
Reaction time premature initiation rate0.30.40.8-0.9-0.4-0.70.10.9-0.90.10.6-0.8
Reaction time premature initiations0.10.20.7-0.8-0.6-0.30.20.3-0.40.50.2-0.4
Std. dev. reaction times1.72.44.12.0-1.11.51.1-1.31.51.7-1.71.6
Reaction time trials completed0.40.61.10.2-1.01.00.8-1.00.40.9-0.60.4
Reaction time trials AUC0.30.51.1-0.0-1.00.90.8-1.00.30.8-0.50.3
Run reversals in cocaine runway, females1.31.31.9-0.5-1.11.00.8-1.31.41.2-1.21.4
Run reversals in cocaine runway, males0.90.92.7-0.31.0-0.2-0.80.5-1.6-0.71.4-0.9
Latency to leave start box in cocaine runway0.10.10.5-0.6-0.1-0.2-0.40.2-0.2-0.30.1-0.7
Latency to leave start box in cocaine runway, F2.02.14.7-0.70.9-0.9-1.11.2-2.2-1.31.9-2.2
Latency to leave start box in cocaine runway, M1.61.55.9-0.5-0.50.40.1-0.82.40.6-2.11.3
Std. dev. time between licks in bursts0.91.02.61.1-1.61.01.4-0.50.71.0-0.70.7
Total sessions with >9 infusions0.30.42.5-1.6-0.3-0.3-0.20.1-0.0-0.80.4-0.0
Short access day 1 total inactive lever presses0.00.00.1-0.1-0.00.10.0-0.2-0.1-0.2-0.0-0.1
Short access day 10 total inactive lever presses0.70.86.02.50.40.60.1-0.8-0.10.2-0.3-0.1
Short access day 1 total infusions0.40.52.7-1.6-0.1-0.6-0.30.3-0.1-0.90.5-0.1
Short access day 10 total infusions0.80.94.4-2.10.3-1.0-0.60.8-0.0-1.00.5-0.0
Short access total infusions0.70.84.8-2.2-0.0-0.7-0.50.5-0.1-0.90.6-0.1
Short access day 1 locomotion0.50.52.4-1.50.6-0.8-0.80.4-0.0-0.60.2-0.0
Short access day 10 total locomotion0.00.10.2-0.30.2-0.3-0.10.3-0.0-0.40.2-0.0
Short access total locomotion0.70.72.1-1.50.9-1.1-1.00.8-0.1-0.90.4-0.1
One hour access (0.3 mA shock)1.21.32.5-1.60.9-1.4-1.61.4-0.2-1.30.8-0.2
Compulsive drug intake0.30.32.11.4-0.20.20.3-0.2-0.00.3-0.1-0.0
One hour access (shock baseline)1.31.64.1-2.01.2-1.4-1.61.4-0.1-1.30.6-0.1
Social response proportion1.21.32.9-1.2-1.71.61.0-1.10.71.0-0.80.6
Social responses0.60.81.3-0.9-1.11.00.5-0.70.81.1-0.90.7
Social time0.91.32.0-1.0-0.61.20.3-1.41.11.3-1.41.2
Soleus weight0.92.64.3-0.2-2.11.52.0-1.51.52.0-1.61.5
Bone: stiffness1.01.63.5-1.5-1.91.21.4-1.00.91.3-0.90.8
Tibialis anterior weight2.06.711.31.1-3.42.93.0-2.42.32.9-2.52.2
Time to tail flick, vehicle, before self-admin2.32.35.3-1.41.9-2.3-2.02.0-0.2-1.20.7-0.2
Time to tail flick, vehicle, after self-admin0.30.41.11.0-0.40.60.8-0.9-0.20.4-0.1-0.2
Time to tail flick, test, before self-admin0.10.10.3-0.2-0.6-0.10.3-0.30.0-0.10.00.0
Time to tail flick, test, after self-admin0.00.00.1-0.30.10.2-0.2-0.1-0.1-0.10.1-0.1
Delta time to tail flick, vehicle, before/after SA1.61.63.51.4-1.41.81.7-1.90.00.9-0.50.0
Delta time to tail flick, test, before/after SA0.10.10.40.10.60.4-0.50.2-0.1-0.00.1-0.1
Tibia length1.33.721.8-4.70.4-1.9-1.61.80.4-1.30.60.2
Ambulatory time before self-admin0.00.00.1-0.40.20.0-0.1-0.20.10.1-0.20.1
Ambulatory time after self-admin0.20.20.7-0.7-0.8-0.10.6-0.00.00.5-0.10.0
Bone: tissue strength0.40.30.5-0.5-0.50.70.6-0.60.60.6-0.60.5
Total heroin consumption0.10.20.50.5-0.5-0.00.7-0.2-0.20.70.0-0.2
Bone: trabecular number0.20.30.70.6-0.20.50.3-0.60.70.8-0.90.4
Bone: trabecular spacing0.10.20.80.90.2-0.00.0-0.10.50.1-0.40.7
Bone: trabecular thickness0.10.10.5-0.70.1-0.1-0.1-0.2-0.00.1-0.1-0.2
Bone: trabecular tissue density2.12.94.5-0.91.0-1.6-1.51.7-2.1-1.92.1-2.1
Water consumed over 24 hours0.20.21.1-1.00.4-0.5-0.50.50.0-0.20.00.0
Number of responses in last shaping day0.30.31.3-1.10.4-0.1-0.70.1-0.0-0.80.2-0.0