Hub : Genes

Cep83os

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Cep83os 0.21 0.08 0.0e+00 0.11 0.15 0.15 0.16 5.8e-12 3.8e-16 1.9e-16 1.7e-17
2 Brain gene expression Cep83os 0.45 0.09 0.0e+00 0.11 0.26 0.28 0.28 2.7e-10 1.1e-23 7.8e-26 5.2e-26
3 LHb gene expression Cep83os 0.45 0.16 6.0e-03 0.02 -0.01 0.05 0.03 1.2e-01 5.8e-01 2.6e-02 8.3e-02
4 OFC gene expression Cep83os 0.56 0.13 4.6e-05 0.05 0.23 0.18 0.25 2.6e-02 3.9e-06 5.7e-05 9.8e-07
5 PL gene expression Cep83os 0.55 0.09 0.0e+00 0.17 0.3 0.31 0.32 1.6e-18 8.8e-33 3.9e-34 4.5e-35
6 Adipose mRNA stability Cep83os 0.09 0.05 1.7e-03 0.03 0.02 0.01 0.03 1.6e-04 6.0e-03 3.1e-02 1.6e-04
7 BLA gene expression Cep83os 0.62 0.1 3.9e-16 0.08 0.26 0.25 0.24 6.5e-05 3.7e-14 1.2e-13 3.4e-13
8 IL gene expression Cep83os 0.81 0.07 7.3e-08 0.14 0.23 0.18 0.3 4.0e-04 3.7e-06 5.0e-05 5.8e-08
9 NAcc gene expression Cep83os 0.64 0.06 2.4e-09 0 0.08 0.08 0.03 3.6e-01 5.3e-12 3.1e-12 4.7e-05
10 pVTA gene expression Cep83os 0.09 0.05 1.4e-05 0.08 0.06 0.06 0.06 1.0e-06 3.0e-05 7.6e-06 1.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.40.61.6-0.5-0.5-1.0-0.8-1.0-1.0-0.9-1.30.00.0
Area under the delay curve7.18.313.0-1.8-3.3-3.6-3.1-2.9-2.9-2.9-2.8-3.1-1.8
BMI with tail0.10.42.11.5-0.1-1.1-0.0-0.0-0.0-0.3-0.60.0-0.5
BMI without tail0.41.27.22.70.5-1.10.2-0.1-0.90.3-0.8-0.21.4
Body weight0.93.824.75.01.1-1.50.60.1-1.40.7-1.1-0.72.4
Weight adjusted by age0.20.30.50.20.70.60.70.60.50.50.60.40.6
Bone surface0.91.73.3-0.4-1.2-1.8-1.4-1.5-1.7-1.1-1.7-1.0-0.3
Bone volume0.71.32.3-0.3-1.0-1.5-1.2-1.3-1.4-1.1-1.5-0.7-0.2
Breakpoint value in progressive ratio session0.60.71.9-1.4-0.9-0.2-0.7-0.60.1-0.8-0.8-0.5-1.3
Number of licking bursts0.10.10.30.50.10.60.20.10.10.4-0.50.20.1
Context. condit. distance diff. score0.30.41.50.60.40.40.60.70.50.51.20.60.3
Locomotion velocity, session 10.20.20.8-0.90.10.70.10.30.5-0.10.20.3-0.4
Locomotion distance, session 10.10.10.3-0.4-0.00.60.10.20.30.3-0.20.0-0.4
Locomotion velocity, session 20.20.21.00.00.41.00.40.30.30.10.6-0.00.5
Locomotion distance, session 20.00.00.10.3-0.10.10.00.00.00.1-0.30.0-0.1
Locomotion velocity, session 30.20.21.0-0.6-0.10.5-0.2-0.2-0.0-1.00.40.4-0.3
Locomotion distance, session 30.00.10.20.1-0.1-0.10.10.10.2-0.20.30.4-0.2
Stereotopy head waving bouts, day 30.20.20.9-1.0-0.1-0.6-0.4-0.3-0.2-0.4-0.70.2-0.4
Stereotopy head waving duration, day 30.40.51.1-0.8-0.4-0.1-0.7-0.8-0.7-1.1-0.8-0.8-0.2
Locomotion velocity, session 73.63.96.01.11.81.62.22.42.41.92.52.30.7
Locomotion distance, session 70.60.82.40.30.60.61.01.01.10.41.21.60.4
Stereotopy head waving bouts, day 70.80.92.20.31.21.51.01.01.10.70.81.00.2
Stereotopy head waving duration, day 70.10.10.5-0.20.60.70.30.20.50.00.10.1-0.2
Locomotion velocity, session 80.10.20.80.30.50.30.30.2-0.10.10.40.40.9
Locomotion distance, session 80.30.51.31.10.50.40.70.80.50.70.90.20.5
Degree of sensitization distance0.10.10.1-0.2-0.3-0.4-0.1-0.2-0.1-0.3-0.10.30.1
Degree of sensitization stereotypy0.91.02.40.11.01.50.90.91.30.41.11.2-0.2
Conditioned locomotion0.20.20.50.10.30.00.40.70.60.30.70.5-0.3
Cocaine response after cond. corrected2.93.56.4-0.5-1.8-2.0-2.0-2.2-2.5-1.8-2.3-2.00.0
Cocaine response after cond. not corrected2.63.05.2-0.3-1.5-2.0-1.7-1.9-2.3-1.6-2.2-2.30.2
Cocaine response before conditioning0.20.20.60.20.50.60.50.60.60.70.3-0.40.1
Saline control response0.50.72.50.90.81.60.70.40.20.20.80.71.0
Bone: connectivity density0.40.71.6-0.6-0.5-0.9-0.7-1.1-1.1-0.8-1.2-0.10.5
Bone: cortical apparent density3.95.48.81.32.41.62.53.02.82.42.72.60.3
Bone: cortical area1.93.05.9-0.0-1.5-2.0-1.8-1.9-2.3-1.2-2.4-2.0-0.1
Bone: cortical porosity2.02.14.0-0.7-1.3-1.7-1.6-1.8-2.0-1.5-1.5-1.30.0
Bone: cortical porosity2.42.74.5-0.8-1.5-1.9-1.8-1.9-2.1-1.6-1.8-1.6-0.2
Bone: cortical thickness1.52.55.5-0.1-1.2-1.5-1.7-1.9-2.3-1.3-2.1-1.80.3
Bone: cortical thickness1.11.31.9-1.3-1.2-1.1-1.4-1.3-1.2-1.2-1.3-0.5-0.6
Bone: cortical tissue density4.25.79.31.42.51.82.63.02.92.52.92.60.4
Condit. Reinf. active minus inactive responses0.20.31.0-1.00.00.8-0.20.20.40.40.30.1-0.8
Condit. Reinf. active-inactive response ratio0.50.51.7-1.3-0.60.0-0.9-0.5-0.2-0.3-0.4-0.5-1.3
Condit. Reinf. active responses0.20.31.6-1.3-0.10.6-0.2-0.10.20.3-0.10.5-0.6
Condit. Reinf. inactive responses0.10.20.9-0.8-0.00.10.1-0.00.30.2-0.10.9-0.0
Incentive salience index mean0.10.20.7-0.40.30.8-0.10.10.10.7-0.20.2-0.2
Condit. Reinf. lever presses0.10.20.70.10.50.50.00.2-0.00.8-0.40.50.1
Condit. Reinf. active minus inactive responses1.21.63.60.11.01.91.21.21.60.81.61.7-0.1
Condit. Reinf. active-inactive response ratio0.20.21.40.00.11.20.0-0.2-0.0-0.60.40.30.2
Condit. Reinf. active responses1.62.24.20.31.21.71.51.72.01.41.61.9-0.3
Condit. Reinf. inactive responses0.60.81.9-0.50.4-0.10.61.11.41.40.60.7-1.0
Condit. Reinf. lever presses2.43.48.50.71.71.72.01.92.21.71.82.90.4
Condit. Reinf. lever reinforcers received1.92.75.50.31.31.81.71.92.41.61.81.9-0.4
Conditioned reinforcement - actives0.20.30.70.70.80.70.40.40.00.40.10.30.8
Conditioned reinforcement - inactives0.00.00.2-0.00.2-0.1-0.1-0.0-0.10.2-0.40.1-0.0
Conditioned locomotion0.10.20.40.60.60.60.40.40.10.40.3-0.10.5
Patch foraging indifference point 0 sec0.10.10.40.50.1-0.30.0-0.1-0.30.3-0.5-0.20.6
Patch foraging indifference point AUC0.20.31.30.90.50.10.2-0.2-0.40.1-0.40.51.1
Delay disc. indifference point, 0s delay0.40.40.8-0.6-0.6-0.9-0.4-0.40.0-0.5-0.9-0.4-0.9
Delay disc. indifference point, 16s delay6.97.512.4-1.8-3.1-3.5-3.0-2.7-2.6-2.7-2.6-2.9-2.2
Delay disc. indifference point, 2s delay0.40.51.2-0.2-0.8-0.8-0.6-0.6-0.7-0.7-0.5-1.1-0.3
Delay disc. indifference point, 24s delay7.07.913.0-1.4-2.9-3.4-3.1-2.8-3.0-2.6-2.8-3.6-1.4
Delay disc. indifference point, 4s delay2.93.04.7-1.0-1.8-2.2-1.8-1.8-2.0-1.7-1.7-2.2-0.4
Delay disc. indifference point, 8s delay9.210.715.4-2.3-3.7-3.9-3.7-3.5-3.4-3.4-3.1-3.1-2.0
Indifference point function ln k0.10.20.8-0.5-0.6-0.3-0.4-0.0-0.00.1-0.2-0.6-0.9
Indifference point function log k0.10.20.8-0.5-0.6-0.3-0.4-0.0-0.00.1-0.2-0.6-0.9
Patch foraging total patch changes 0 sec0.10.10.40.40.1-0.3-0.1-0.2-0.40.2-0.6-0.30.6
Patch foraging total patch changes 12 sec0.81.15.21.70.90.10.5-0.2-0.70.5-0.80.42.3
Patch foraging total patch changes 18 sec1.52.35.42.21.81.41.41.00.41.80.50.92.3
Patch foraging total patch changes 24 sec0.61.04.21.80.70.70.4-0.2-0.70.5-0.30.12.1
Patch foraging total patch changes 6 sec0.10.20.50.60.2-0.30.0-0.3-0.30.3-0.60.10.7
Patch foraging time to switch 0 sec0.40.71.90.20.90.61.01.21.20.71.40.40.1
Patch foraging water rate 0 sec0.20.41.01.0-0.2-0.7-0.3-0.4-0.70.4-1.0-0.50.2
Patch foraging water rate 12 sec0.51.03.61.90.71.50.6-0.0-0.40.2-0.20.71.6
Patch foraging water rate 18 sec0.10.20.8-0.1-0.10.9-0.1-0.20.2-0.60.00.5-0.6
Patch foraging water rate 24 sec0.30.52.71.70.40.50.60.70.20.70.0-0.10.6
Patch foraging water rate 6 sec1.21.75.62.41.21.31.41.30.81.40.40.71.1
Seeking ratio, delayed vs. immediate footshock0.60.82.4-0.3-0.9-0.7-0.9-1.1-1.2-0.3-1.5-0.50.1
Distance traveled before self-admin0.00.10.2-0.1-0.20.1-0.1-0.2-0.1-0.5-0.30.1-0.2
Distance traveled after self-admin0.60.72.2-1.2-1.0-0.7-0.8-0.6-0.1-0.9-0.6-0.4-1.5
Extensor digitorum longus weight0.83.25.1-0.5-1.7-1.8-2.1-2.2-2.3-1.8-2.1-1.9-0.6
Bone: elastic displacement3.64.26.2-2.5-2.3-1.1-2.4-2.4-2.0-2.4-1.6-2.0-1.3
Bone: elastic work5.87.512.1-2.3-3.0-1.8-3.2-3.5-3.3-2.9-2.8-2.7-0.8
Bone: endosteal estimation0.40.83.3-0.7-1.3-1.4-0.7-0.40.1-0.5-0.4-0.0-1.8
Bone: endosteal perimeter0.71.45.30.2-1.3-2.3-1.0-0.7-1.0-0.2-1.3-1.5-0.8
Epididymis fat weight0.41.54.62.21.20.41.41.41.21.50.50.90.5
Delta time in closed arm before/after self-admin0.00.00.10.3-0.0-0.3-0.0-0.1-0.1-0.20.1-0.2-0.0
Delta time in open arm before/after self-admin0.40.41.7-1.3-0.70.0-0.6-0.5-0.1-0.6-0.50.6-0.8
Diff in mean of infusions in LGA sessions0.10.10.4-0.4-0.20.7-0.2-0.3-0.1-0.6-0.1-0.00.0
Delay discount exponential model param7.28.112.51.73.23.53.12.93.02.92.73.21.6
Extinction: sum of active levers before priming0.10.10.5-0.5-0.4-0.1-0.3-0.30.0-0.6-0.00.0-0.7
Active lever presses in extinction session 60.10.10.3-0.4-0.40.1-0.2-0.20.1-0.6-0.2-0.2-0.6
Bone: final force1.52.43.8-0.7-1.9-1.5-1.8-1.9-1.7-1.6-2.0-1.0-0.9
Bone: final moment2.23.66.1-0.9-2.1-1.7-2.1-2.3-2.2-1.9-2.5-1.5-0.8
Food consumed during 24 hour testing period0.91.32.01.21.21.41.11.00.71.30.71.41.1
Glucose0.30.41.90.20.41.00.60.40.70.30.21.40.2
Heart weight1.21.93.4-0.1-1.5-1.7-1.4-1.6-1.6-1.1-1.8-1.2-0.6
Delay discount hyperbolic model param6.87.611.81.53.13.43.02.93.02.72.63.21.3
Intermittent access intake day 1-15 change0.51.02.51.61.40.90.90.60.21.10.20.11.6
Intermittent access intake escalation0.50.92.41.61.30.70.90.60.21.20.1-0.01.5
Intermittent access intake escalation 20.50.61.51.21.00.80.70.50.20.80.3-0.21.2
Intermitt. access day 1 inactive lever presses0.10.41.9-1.4-0.5-0.0-0.5-0.4-0.1-0.5-0.00.4-0.8
Intermitt. access day 15 inactive lever presses0.10.20.7-0.8-0.20.2-0.4-0.20.0-0.50.1-0.2-0.8
Intermitt. access escalation Index0.10.10.3-0.40.20.50.00.20.2-0.10.30.3-0.3
Intermittent access day 1 total infusions0.10.20.90.90.20.30.30.4-0.1-0.10.70.00.5
Intermittent access day 15 total infusions0.50.82.91.70.90.70.80.60.10.60.6-0.11.3
Intermittent access terminal intake (last 3 days)0.30.41.91.40.60.30.60.50.00.40.6-0.30.9
Intermittent access total infusions0.20.31.31.10.40.30.40.40.00.20.6-0.10.6
Intermittent access day 1 locomotion0.10.10.70.40.10.40.10.3-0.0-0.20.8-0.00.1
Intermittent access day 15 total locomotion0.30.61.11.01.10.80.70.60.10.70.7-0.21.1
Intermittent access total locomotion0.20.20.70.80.40.50.40.40.10.10.8-0.20.5
Intermittent access standard deviation0.51.03.11.81.20.90.90.60.00.90.40.11.6
Left kidney weight0.31.68.42.90.9-0.30.3-0.1-1.00.3-0.9-0.91.9
Right kidney weight0.21.06.22.50.4-0.70.3-0.1-0.60.4-0.8-0.61.0
Cocaine induced anxiety0.81.13.8-1.9-1.1-0.3-1.1-0.7-0.1-0.9-0.4-0.1-1.9
Post-drug Anxiety0.50.51.8-1.3-0.60.4-0.7-0.5-0.1-0.9-0.2-0.2-1.2
Baseline Anxiety0.60.72.11.40.80.90.80.40.10.30.50.01.4
Tail length1.76.628.55.32.2-0.41.40.7-1.51.9-0.2-0.74.8
Length with tail1.87.838.16.22.6-0.21.80.9-1.32.0-0.1-0.54.8
Length without tail0.62.011.73.41.4-0.11.10.7-0.20.90.10.11.9
Times rat made contact with spout1.41.65.32.31.31.10.90.3-0.31.0-0.61.22.1
Lifetime Intake0.20.21.21.10.30.10.40.40.00.20.6-0.10.5
Liver weight, left1.11.88.73.01.20.40.70.1-0.90.7-0.4-0.02.5
Liver weight, right0.91.55.42.31.30.40.90.5-0.41.0-0.20.82.2
Locomotor activity0.40.63.41.80.5-0.50.50.3-0.10.7-0.4-0.10.9
Locomotor testing distance0.20.31.41.20.2-0.80.40.50.30.6-0.20.10.0
Locomotor testing rearing0.20.41.60.6-0.2-1.3-0.3-0.2-0.70.2-0.8-0.70.3
Locomotion in novel chamber0.00.10.10.1-0.1-0.1-0.00.20.10.40.3-0.4-0.3
Locomotion in novel chamber post-restriction0.00.00.30.50.2-0.20.10.1-0.1-0.00.1-0.10.2
Fecal boli incidents, locomotor time 10.10.20.50.30.3-0.10.40.50.20.70.20.50.5
Change in fecal boli incidents, locomotor task0.80.72.2-1.0-0.30.70.10.51.1-0.31.4-0.1-1.5
Time >=10cm from walls, locomotor time 11.11.22.3-1.5-1.4-1.1-1.1-0.9-0.5-1.3-0.4-0.5-1.4
Bouts of movement, locomotor time 12.32.64.7-1.3-1.7-2.2-1.7-1.7-1.4-1.4-2.1-0.9-1.1
Total resting periods, locomotor time 11.71.83.2-1.3-1.4-1.8-1.5-1.5-1.1-1.1-1.8-0.8-1.0
Rest time, locomotor task time 10.50.62.3-1.5-0.6-0.7-0.7-0.7-0.3-0.7-0.7-0.3-0.8
Distance moved, locomotor task time 11.21.73.31.71.41.11.41.40.91.80.91.01.2
Vertical activity count, locomotor time 10.61.53.61.91.10.91.41.41.01.51.00.71.0
Time >=10cm from walls, locomotor time 20.00.00.2-0.30.40.20.10.10.10.0-0.20.20.3
Bouts of movement, locomotor time 21.52.43.8-0.9-1.6-1.8-1.7-1.7-1.7-1.3-1.6-1.9-0.7
Total resting periods, locomotor time 21.73.04.3-1.3-1.9-2.1-1.9-1.8-1.7-1.6-1.7-2.1-1.1
Rest time, locomotor task time 20.70.92.6-1.6-1.1-0.8-0.7-0.60.1-1.2-0.3-0.6-1.3
Distance moved, locomotor task time 21.82.23.41.61.81.61.51.30.81.60.61.81.6
Vertical activity count, locomotor time 21.62.25.12.21.71.01.51.10.51.40.21.82.1
Light reinforcement 10.71.83.40.81.61.31.61.51.91.01.21.50.2
Light reinforcement 20.30.51.2-0.60.20.10.30.61.0-0.10.81.1-1.1
Bone: marrow area0.40.83.4-0.7-1.3-1.4-0.6-0.30.2-0.5-0.4-0.0-1.8
Bone: maximum diameter0.40.82.50.5-0.8-1.6-0.7-0.6-0.8-0.1-1.3-1.2-0.5
Bone: maximum force1.72.94.2-1.1-2.1-1.7-1.9-2.0-1.8-1.7-2.0-1.4-1.1
Bone: maximum moment2.64.56.5-1.3-2.4-2.0-2.4-2.6-2.3-2.1-2.6-1.9-1.1
Mean time between licks in bursts0.40.92.6-0.6-1.0-0.9-1.0-0.8-0.8-0.4-1.0-1.6-0.8
Mean num. licks in bursts0.10.20.60.60.50.10.30.2-0.10.20.30.70.8
Cd content in liver0.20.21.0-0.4-0.4-1.0-0.0-0.20.2-0.4-0.30.2-0.4
Co content in liver0.40.42.10.50.5-0.40.60.80.51.40.1-0.40.3
Cu content in liver0.30.41.90.60.60.60.40.30.20.30.11.40.5
Fe content in liver1.51.82.5-1.0-1.6-1.2-1.5-1.4-1.2-1.5-0.9-1.5-1.2
K content in liver3.12.94.71.72.11.41.61.40.72.11.02.22.1
Mg content in liver0.60.61.60.51.00.40.70.70.51.30.41.10.7
Mn content in liver1.21.43.50.91.00.41.31.21.21.61.01.90.6
Na content in liver0.70.81.80.51.10.70.90.90.71.00.71.30.8
Rb content in liver1.01.22.7-0.8-1.1-0.9-1.4-1.4-1.7-1.0-1.1-0.40.0
Se content in liver2.12.56.00.41.11.71.41.72.01.52.02.5-0.5
Sr content in liver0.50.51.4-0.1-0.1-0.9-0.3-0.7-0.7-0.7-1.2-0.60.7
Zn content in liver3.94.36.82.62.52.02.32.01.42.21.61.52.3
Bone: minimum diameter0.61.03.50.9-0.8-1.9-0.7-0.7-1.0-0.4-1.3-1.1-0.4
Time in familiar zone, hab. session 10.20.20.6-0.4-0.10.8-0.10.10.40.30.2-0.6-0.8
Time in novel zone, hab. session 10.40.41.9-0.5-0.6-1.4-0.3-0.3-0.2-0.80.20.8-0.2
Total zone transitions, hab. session 10.40.61.61.10.80.90.80.70.41.2-0.20.10.8
Total locomotion distance, hab. session 11.21.73.81.31.62.01.41.41.21.50.60.60.7
Locomotion velocity, hab. session 11.82.54.81.72.02.21.71.71.32.00.50.61.2
Time in familiar zone, hab. session 20.10.10.2-0.3-0.3-0.2-0.4-0.3-0.2-0.4-0.0-0.0-0.4
Time in novel zone, hab. session 20.40.40.7-0.8-0.8-0.8-0.5-0.4-0.2-0.6-0.3-0.4-0.8
Total zone transitions, hab. session 20.20.21.0-0.5-0.20.2-0.20.10.20.2-0.3-1.0-0.9
Total locomotion distance, hab. session 20.30.30.7-0.20.50.60.40.80.90.80.1-0.2-0.7
Locomotion velocity, hab. session 20.40.51.2-0.10.60.70.61.01.01.10.1-0.2-0.6
Novel to familiar place preference ratio1.81.92.81.01.61.71.61.51.21.51.30.81.5
Novelty place preference1.61.72.40.81.51.61.51.41.21.41.30.81.4
Time in novel zone, NPP test1.31.41.90.71.31.41.41.21.11.21.20.71.2
Total zone transitions, NPP test0.30.51.2-0.2-0.8-0.7-0.7-0.6-0.6-0.2-0.9-1.1-0.5
Total locomotion distance, NPP test0.30.50.90.60.70.70.80.90.81.00.20.40.1
Locomotion velocity, NPP test0.60.81.50.61.01.01.01.21.11.20.50.60.2
Intraocular pressure0.10.10.5-0.7-0.3-0.6-0.1-0.20.1-0.3-0.2-0.0-0.4
Delta distance traveled before/after self-admin0.10.10.4-0.5-0.4-0.5-0.4-0.3-0.1-0.1-0.3-0.2-0.6
Delta ambulatory time before/after self-admin0.40.51.6-1.2-0.8-0.9-0.7-0.4-0.1-0.4-0.3-0.3-1.3
Parametrial fat weight0.40.94.4-1.0-1.0-1.1-0.7-0.20.4-0.5-0.3-0.4-2.1
Pavlov. Cond. lever latency0.20.21.0-0.2-0.6-1.0-0.00.00.1-0.40.4-0.4-0.4
Pavlov. Cond. magazine entry latency1.31.73.60.21.31.11.31.71.91.41.41.3-0.5
Pavlov. Cond. change in total contacts1.41.52.51.01.21.51.31.31.41.40.91.60.2
Pavlov. Cond. index score0.40.51.00.00.90.90.60.81.00.80.41.0-0.4
Pavlov. Cond. latency score0.40.51.1-0.00.91.10.60.70.90.70.31.0-0.2
Pavlov. Cond. lever contacts0.30.41.40.40.81.20.40.30.20.6-0.20.70.6
Pavlov. Cond. magazine entry number0.91.22.8-0.0-1.0-0.7-1.0-1.4-1.7-1.0-1.2-1.10.9
Pavlov. Cond. intertrial magazine entries0.60.81.9-0.4-1.3-0.9-0.9-0.7-0.6-0.7-0.3-1.4-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.6-0.10.60.60.30.60.80.60.10.7-0.6
Pavlov. Cond. response bias1.11.42.20.41.31.41.11.41.51.41.01.3-0.2
Pavlov. Cond. lever latency1.52.04.3-0.4-1.0-1.4-1.4-1.6-2.0-1.3-1.6-2.10.4
Pavlov. Cond. magazine entry latency1.21.52.81.11.31.21.41.41.31.01.70.90.7
Pavlov. Cond. change in total contacts1.32.13.41.41.21.11.61.81.71.81.61.20.3
Pavlov. Cond. index score2.63.55.31.41.81.62.12.32.22.02.21.80.6
Pavlov. Cond. latency score2.93.85.81.31.91.62.22.42.42.12.32.00.5
Pavlov. Cond. lever contacts1.31.83.90.40.91.31.41.51.91.21.42.0-0.5
Pavlov. Cond. magazine entry number3.64.57.3-1.6-2.1-1.7-2.4-2.7-2.7-2.0-2.6-1.9-0.3
Pavlov. Cond. intertrial magazine entries0.50.71.3-0.7-0.8-0.7-0.9-1.1-1.0-0.7-1.1-0.70.0
Pavlov. Cond. lever-magazine prob. diff.2.93.85.61.62.01.72.22.42.22.02.31.80.8
Pavlov. Cond. response bias1.11.52.70.71.01.31.31.51.61.21.41.6-0.2
Time in closed arm before self-admin0.10.20.40.60.40.30.40.30.10.50.3-0.20.7
Time in closed arm after self-admin0.00.00.10.2-0.1-0.30.1-0.10.0-0.30.1-0.2-0.0
Time in open arm before self-admin0.10.10.6-0.4-0.2-0.8-0.3-0.2-0.0-0.2-0.4-0.2-0.5
Time in open arm after self-admin0.50.51.9-1.4-0.8-0.5-0.7-0.5-0.1-0.5-0.50.3-1.0
Bone: periosteal estimation0.91.94.2-0.5-1.7-2.0-1.4-1.2-1.1-1.0-1.5-1.4-1.5
Bone: periosteal perimeter1.52.67.0-0.5-1.7-2.7-1.7-1.5-1.6-1.0-1.9-1.5-0.9
Bone: post-yield work0.20.31.0-0.4-0.50.6-0.4-0.5-0.2-1.0-0.00.3-0.6
Progressive ratio test 1 active lever presses1.11.35.42.31.10.71.00.80.00.60.70.51.7
Progressive ratio test 1 breakpoint1.21.45.72.41.20.81.10.90.00.70.80.51.8
Progressive ratio test 1 inactive lever presses0.00.00.10.10.10.10.00.0-0.10.00.00.30.0
Progressive ratio test 2 active lever presses0.60.72.11.41.00.90.80.60.10.50.70.11.2
Progressive ratio test 2 breakpoint0.70.82.21.51.10.90.80.60.10.60.7-0.01.3
Progressive ratio test 2 inactive lever presses0.10.10.60.20.40.80.20.0-0.0-0.30.40.20.3
Incentive Sensitization - Responses0.40.51.21.11.00.70.60.40.00.70.5-0.11.1
Incentive Sensitization - Breakpoint0.30.40.91.00.90.70.50.40.00.60.5-0.21.0
Sum of active levers in priming session hrs 5-60.60.61.21.11.01.10.70.40.30.6-0.10.51.1
Progressive ratio0.60.92.8-1.3-1.2-0.4-1.0-0.6-0.4-0.50.0-1.7-1.2
Food seeking constrained by brief footshock0.91.12.81.71.01.60.80.60.10.61.10.11.4
Seeking ratio, punishment vs. effort0.60.92.01.41.30.91.00.60.40.40.31.31.2
Retroperitoneal fat weight0.52.26.92.61.70.51.61.61.12.00.60.41.1
Reaction time number correct0.50.91.7-0.6-1.0-0.8-1.0-1.1-0.8-1.3-1.0-0.8-0.8
Reaction time mean minus median0.30.81.8-1.2-0.8-1.3-0.9-1.0-0.7-0.9-0.9-0.6-0.4
Reaction time mean minus median AUC0.41.01.9-1.0-1.0-0.9-1.2-1.4-1.3-0.7-1.3-0.6-0.2
Reaction time num false alarms0.50.71.3-1.0-0.7-0.3-1.0-1.1-1.0-0.9-0.9-0.1-0.3
Reaction time num false alarms AUC0.81.32.1-1.5-1.1-0.4-1.4-1.4-1.1-1.3-1.2-0.3-0.8
Reaction time trials correct on left0.50.91.7-0.6-1.0-0.8-1.0-1.1-0.8-1.3-1.0-0.8-0.8
Reaction time trials on left0.61.01.9-0.7-1.1-0.9-1.1-1.2-0.9-1.4-1.0-0.9-0.9
Reaction time mean0.30.41.9-0.4-0.7-1.4-0.5-0.4-0.3-0.4-0.5-0.6-0.6
Reaction time mean AUC0.30.42.1-0.2-0.6-1.4-0.5-0.5-0.4-0.5-0.5-0.6-0.4
Median of all reaction times0.10.10.80.2-0.3-0.9-0.00.10.10.0-0.0-0.4-0.5
Reaction time omissions1.62.35.7-2.4-1.7-1.5-1.5-1.2-0.7-1.5-1.0-1.0-1.8
Reaction time false alarm rate0.20.20.9-0.9-0.40.2-0.6-0.5-0.4-0.3-0.30.3-0.4
Reaction time premature initiation rate0.20.31.0-0.1-0.00.10.20.30.60.8-0.71.0-0.8
Reaction time premature initiations0.10.21.3-0.1-0.3-0.2-0.2-0.30.00.1-1.10.6-0.6
Std. dev. reaction times0.81.62.7-1.5-1.3-1.6-1.3-1.3-1.0-1.2-1.3-1.0-0.8
Reaction time trials completed0.61.01.9-0.7-1.1-0.9-1.1-1.2-0.9-1.4-1.0-0.9-0.9
Reaction time trials AUC0.50.91.6-0.6-1.0-0.8-1.0-1.1-0.7-1.3-0.9-0.8-0.9
Run reversals in cocaine runway, females1.21.22.1-0.2-0.9-1.3-1.1-1.1-1.4-1.1-1.5-1.4-0.1
Run reversals in cocaine runway, males1.71.73.30.51.41.11.61.51.70.41.81.70.4
Latency to leave start box in cocaine runway0.00.10.10.30.4-0.20.30.10.20.00.20.30.2
Latency to leave start box in cocaine runway, F1.61.84.70.01.20.51.51.72.20.91.81.5-0.4
Latency to leave start box in cocaine runway, M2.52.36.60.6-0.8-0.5-1.5-2.1-2.6-1.1-2.0-1.41.1
Std. dev. time between licks in bursts1.11.52.4-1.3-1.5-1.4-1.4-1.0-0.8-0.4-1.0-1.5-1.4
Total sessions with >9 infusions0.30.41.91.40.50.20.60.50.00.40.30.40.9
Short access day 1 total inactive lever presses0.10.10.3-0.3-0.30.1-0.2-0.3-0.1-0.60.10.4-0.3
Short access day 10 total inactive lever presses0.30.74.2-2.0-0.60.5-0.6-0.40.1-0.70.30.1-1.2
Short access day 1 total infusions0.00.00.2-0.1-0.3-0.1-0.00.00.1-0.40.3-0.1-0.3
Short access day 10 total infusions0.20.21.21.10.30.10.40.4-0.10.20.50.40.6
Short access total infusions0.10.10.40.60.10.00.30.40.10.10.50.10.2
Short access day 1 locomotion0.20.20.70.80.50.50.40.10.0-0.00.10.60.8
Short access day 10 total locomotion0.10.10.4-0.6-0.5-0.1-0.3-0.1-0.0-0.20.40.1-0.6
Short access total locomotion0.50.71.71.20.90.80.70.50.00.70.50.61.3
One hour access (0.3 mA shock)1.82.07.12.71.60.91.31.10.21.40.7-0.42.1
Compulsive drug intake0.10.10.30.30.60.30.20.4-0.00.60.2-0.30.5
One hour access (shock baseline)0.71.14.22.11.10.61.00.60.10.80.5-0.01.6
Social response proportion0.50.61.5-0.1-0.8-0.8-0.8-0.9-0.8-1.2-0.9-0.3-0.6
Social responses0.50.71.9-0.1-0.7-0.8-0.9-1.0-0.9-0.9-1.4-0.7-0.3
Social time0.60.93.00.2-0.40.1-0.7-1.4-1.2-1.7-1.2-0.10.5
Soleus weight1.23.64.8-1.3-2.1-1.7-2.2-2.1-1.8-1.9-2.2-1.7-1.7
Bone: stiffness0.30.52.70.2-0.7-1.6-0.4-0.3-0.2-0.3-0.90.1-0.8
Tibialis anterior weight2.27.410.1-2.0-2.9-3.2-3.1-2.8-2.4-2.7-2.6-2.9-2.5
Time to tail flick, vehicle, before self-admin2.32.37.02.51.70.71.50.90.21.9-0.10.42.7
Time to tail flick, vehicle, after self-admin0.30.41.7-1.3-0.50.0-0.5-0.40.0-0.8-0.00.3-0.9
Time to tail flick, test, before self-admin0.20.20.7-0.1-0.4-0.5-0.4-0.1-0.0-0.30.1-0.7-0.8
Time to tail flick, test, after self-admin0.00.00.10.2-0.1-0.20.00.10.1-0.10.1-0.2-0.1
Delta time to tail flick, vehicle, before/after SA2.01.95.9-2.4-1.4-0.3-1.3-0.8-0.1-1.80.2-0.0-2.4
Delta time to tail flick, test, before/after SA0.10.10.40.10.30.30.30.10.10.1-0.00.50.6
Tibia length1.23.417.14.11.8-0.31.51.1-0.21.70.2-0.62.7
Ambulatory time before self-admin0.10.10.40.20.10.60.1-0.2-0.1-0.4-0.30.60.3
Ambulatory time after self-admin0.50.61.7-0.9-0.8-0.8-0.7-0.5-0.1-0.6-0.7-0.4-1.3
Bone: tissue strength0.70.71.3-0.2-0.9-0.9-0.8-1.1-1.1-1.0-1.1-0.3-0.1
Total heroin consumption0.70.82.3-1.2-1.1-0.9-0.7-0.40.1-0.4-1.0-0.6-1.5
Bone: trabecular number0.30.61.3-0.7-0.5-0.8-0.7-1.0-0.8-0.9-1.1-0.00.0
Bone: trabecular spacing0.10.10.60.1-0.1-0.1-0.2-0.0-0.20.1-0.2-0.80.1
Bone: trabecular thickness0.20.31.20.30.70.80.50.20.3-0.10.31.10.5
Bone: trabecular tissue density3.34.98.41.02.31.82.52.92.92.52.62.00.2
Water consumed over 24 hours0.71.03.21.70.90.20.60.0-0.40.3-0.31.41.8
Number of responses in last shaping day0.10.10.60.10.20.40.20.10.1-0.30.8-0.30.2