Hub : Genes

Eno4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Eno4 0.09 0.06 2.4e-09 0.06 0.06 0.07 0.06 9.1e-08 1.1e-07 1.7e-08 1.7e-07
2 NAcc gene expression Eno4 0.1 0.1 5.8e-03 0 0 -0 0 1.3e-01 1.6e-01 7.1e-01 3.3e-01
3 IC intron excision ratio chr1_268094929_268095751 0.12 0.08 6.9e-03 -0 0.01 -0.01 -0 6.2e-01 1.1e-01 7.3e-01 6.0e-01
4 IC intron excision ratio chr1_268082758_268084457 0.15 0.08 6.4e-04 0.06 0.07 0.05 0.06 1.1e-03 7.9e-04 3.2e-03 1.8e-03
5 Brain isoform ratio XR_005500392.2 0.04 0.03 7.0e-03 0.03 0.02 0.01 0.02 1.7e-03 3.3e-03 3.3e-02 5.1e-03
6 Adipose isoform ratio NM_001134505.1 0.03 0.03 5.3e-03 0.01 0.01 0.01 0.01 2.7e-02 1.2e-02 2.0e-02 3.2e-02
7 Adipose alternative TSS XM_006231669.5 0.06 0.04 7.3e-07 0.05 0.04 0.04 0.04 4.9e-06 1.2e-05 3.9e-05 2.1e-05
8 Adipose isoform ratio XR_005500392.2 0.07 0.04 5.5e-07 0.05 0.04 0.05 0.04 5.6e-06 9.8e-06 7.5e-06 7.9e-06
9 NAcc isoform ratio XM_039103299.2 0.13 0.12 1.3e-04 0.01 0.03 0.02 0.02 3.6e-03 9.7e-05 1.9e-04 1.3e-04
10 Adipose alternative TSS XM_039103299.2 0.06 0.04 9.6e-07 0.05 0.04 0.04 0.04 6.5e-06 1.6e-05 5.0e-05 2.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.71.24.31.0-0.9-1.21.42.10.6-0.4-0.4-0.1-1.5
Area under the delay curve1.62.54.42.10.6-1.61.40.51.72.02.01.71.4
BMI with tail4.114.547.66.9-5.2-4.54.03.63.02.32.30.9-0.4
BMI without tail1.57.827.05.2-4.8-3.02.62.41.81.41.40.1-0.5
Body weight4.017.749.57.0-4.9-5.34.94.93.62.22.21.3-1.6
Weight adjusted by age0.51.35.92.3-2.4-0.80.60.40.40.70.70.10.2
Bone surface0.40.82.30.6-1.2-0.70.81.50.1-0.6-0.6-0.4-1.4
Bone volume0.71.53.31.7-1.1-1.61.61.81.10.40.40.4-0.7
Breakpoint value in progressive ratio session1.62.94.51.12.0-2.12.11.72.01.61.61.9-0.4
Number of licking bursts0.41.13.4-1.1-0.20.30.01.0-0.7-1.5-1.5-1.0-1.9
Context. condit. distance diff. score0.91.11.8-0.6-1.31.2-1.1-0.7-1.3-1.1-1.1-1.3-0.4
Locomotion velocity, session 10.10.10.2-0.40.10.4-0.4-0.3-0.3-0.2-0.2-0.2-0.2
Locomotion distance, session 11.01.22.4-1.1-0.41.5-1.6-1.5-1.3-0.8-0.8-1.00.3
Locomotion velocity, session 22.02.44.4-1.8-0.42.1-2.1-1.8-1.8-1.2-1.2-1.40.0
Locomotion distance, session 21.01.42.5-0.4-1.61.4-1.5-1.3-1.4-0.8-0.8-1.40.2
Locomotion velocity, session 30.70.81.5-1.1-0.21.2-1.2-1.1-1.1-0.7-0.7-0.80.2
Locomotion distance, session 31.21.42.9-0.8-1.01.5-1.7-1.7-1.4-0.7-0.7-1.10.7
Stereotopy head waving bouts, day 30.20.21.1-0.41.10.1-0.1-0.40.20.40.40.50.6
Stereotopy head waving duration, day 30.20.32.1-0.61.4-0.10.20.20.30.20.20.50.1
Locomotion velocity, session 70.70.82.0-0.3-1.40.8-0.8-0.4-1.0-1.0-1.0-1.2-0.5
Locomotion distance, session 70.91.22.8-0.3-1.71.2-1.3-1.0-1.3-0.9-0.9-1.30.0
Stereotopy head waving bouts, day 70.10.20.30.50.2-0.50.50.30.50.40.40.40.1
Stereotopy head waving duration, day 71.11.42.00.91.2-1.41.41.01.41.11.11.40.2
Locomotion velocity, session 82.32.84.4-1.9-0.81.8-1.5-0.5-1.9-2.1-2.1-1.9-1.5
Locomotion distance, session 85.07.311.0-2.2-2.53.0-2.9-1.6-3.3-3.0-3.0-3.3-1.4
Degree of sensitization distance0.30.30.90.5-0.4-0.60.71.00.4-0.1-0.10.0-0.7
Degree of sensitization stereotypy0.40.51.11.0-0.5-0.90.91.00.70.30.30.3-0.4
Conditioned locomotion0.20.30.60.30.7-0.60.50.20.70.50.50.60.4
Cocaine response after cond. corrected2.13.28.6-1.90.12.4-2.6-2.9-1.8-0.7-0.7-1.11.4
Cocaine response after cond. not corrected2.02.96.6-2.20.62.3-2.3-2.6-1.7-0.9-0.9-1.00.9
Cocaine response before conditioning0.40.51.5-0.40.9-0.50.81.20.4-0.3-0.30.4-1.2
Saline control response0.20.20.8-0.2-0.20.6-0.7-0.9-0.50.00.0-0.20.6
Bone: connectivity density0.40.61.90.1-0.6-0.40.61.3-0.0-0.8-0.8-0.4-1.4
Bone: cortical apparent density2.03.17.6-2.20.52.4-2.5-2.8-1.8-0.8-0.8-1.01.1
Bone: cortical area1.32.28.11.8-2.8-1.11.22.00.3-0.4-0.4-0.8-1.7
Bone: cortical porosity0.30.30.60.40.4-0.80.80.80.70.40.40.5-0.3
Bone: cortical porosity0.80.92.31.00.1-1.31.31.51.00.40.40.6-0.7
Bone: cortical thickness1.52.614.21.0-3.80.3-0.40.5-1.1-1.3-1.3-2.0-1.4
Bone: cortical thickness0.60.74.81.4-2.2-0.2-0.1-0.1-0.10.30.3-0.50.3
Bone: cortical tissue density2.03.17.5-2.20.72.4-2.5-2.7-1.8-0.8-0.8-1.01.1
Condit. Reinf. active minus inactive responses1.21.32.2-1.1-0.71.2-1.0-0.3-1.3-1.5-1.5-1.3-1.0
Condit. Reinf. active-inactive response ratio0.60.61.5-1.20.40.8-0.5-0.0-0.7-1.0-1.0-0.6-0.7
Condit. Reinf. active responses1.41.84.7-0.2-2.20.8-0.60.3-1.3-1.6-1.6-1.7-1.5
Condit. Reinf. inactive responses1.31.77.40.6-2.70.2-0.10.7-0.8-1.3-1.3-1.6-1.5
Incentive salience index mean1.31.72.5-0.9-1.31.4-1.3-0.7-1.6-1.5-1.5-1.6-0.7
Condit. Reinf. lever presses0.40.71.2-0.3-1.10.9-0.9-0.7-1.0-0.8-0.8-1.0-0.0
Condit. Reinf. active minus inactive responses0.71.03.00.80.5-1.31.51.71.10.40.40.8-0.8
Condit. Reinf. active-inactive response ratio0.30.51.20.80.1-1.01.01.10.70.30.30.5-0.4
Condit. Reinf. active responses1.21.74.91.30.1-1.71.92.21.30.50.50.9-1.0
Condit. Reinf. inactive responses0.50.82.00.90.1-1.21.31.40.90.40.40.7-0.6
Condit. Reinf. lever presses0.40.61.61.0-0.4-1.01.11.30.70.30.30.4-0.6
Condit. Reinf. lever reinforcers received0.71.03.60.80.0-1.21.51.90.90.10.10.5-1.2
Conditioned reinforcement - actives0.41.52.8-1.50.71.7-1.7-1.6-1.3-0.7-0.7-0.80.9
Conditioned reinforcement - inactives0.10.42.0-0.51.4-0.40.60.70.50.30.30.60.1
Conditioned locomotion1.62.44.7-1.70.22.2-2.2-2.0-1.8-1.0-1.0-1.21.0
Patch foraging indifference point 0 sec0.41.15.41.6-2.3-0.70.60.90.1-0.1-0.1-0.6-0.9
Patch foraging indifference point AUC0.20.51.20.9-0.3-1.11.01.00.80.30.30.3-0.5
Delay disc. indifference point, 0s delay0.30.31.20.6-1.10.1-0.3-0.6-0.10.30.3-0.20.7
Delay disc. indifference point, 16s delay1.31.83.01.70.7-1.41.20.51.41.71.71.51.2
Delay disc. indifference point, 2s delay1.31.43.11.20.4-0.60.3-0.80.91.71.71.31.7
Delay disc. indifference point, 24s delay0.81.32.61.60.2-1.41.31.01.31.21.21.10.3
Delay disc. indifference point, 4s delay1.71.83.11.70.7-1.31.10.21.41.81.81.51.4
Delay disc. indifference point, 8s delay1.22.03.11.71.0-1.51.30.51.61.81.81.61.2
Indifference point function ln k0.10.40.6-0.3-0.60.8-0.8-0.5-0.8-0.6-0.6-0.7-0.1
Indifference point function log k0.10.40.6-0.3-0.60.8-0.8-0.5-0.8-0.6-0.6-0.7-0.1
Patch foraging total patch changes 0 sec0.51.46.41.9-2.5-0.80.81.10.2-0.1-0.1-0.6-1.0
Patch foraging total patch changes 12 sec0.81.13.41.5-1.8-1.00.91.30.4-0.1-0.1-0.4-1.1
Patch foraging total patch changes 18 sec0.81.83.61.9-0.7-1.91.91.81.40.60.60.6-0.8
Patch foraging total patch changes 24 sec0.30.92.21.1-0.7-1.31.31.50.90.10.10.2-1.0
Patch foraging total patch changes 6 sec0.91.65.11.5-2.3-1.01.11.70.4-0.3-0.3-0.5-1.7
Patch foraging time to switch 0 sec0.31.05.4-1.22.30.2-0.1-0.60.40.60.61.11.0
Patch foraging water rate 0 sec0.41.48.11.8-2.8-0.50.30.7-0.1-0.3-0.3-0.9-0.9
Patch foraging water rate 12 sec0.31.13.91.4-2.0-0.80.91.30.2-0.3-0.3-0.6-1.3
Patch foraging water rate 18 sec0.20.42.00.6-1.40.4-0.5-0.6-0.5-0.1-0.1-0.60.2
Patch foraging water rate 24 sec0.50.72.71.6-1.6-0.40.1-0.30.30.70.70.10.8
Patch foraging water rate 6 sec0.30.42.11.3-1.5-0.30.2-0.10.10.40.4-0.10.2
Seeking ratio, delayed vs. immediate footshock1.72.44.4-2.10.22.0-1.9-1.3-1.7-1.6-1.6-1.3-0.4
Distance traveled before self-admin1.02.27.8-1.1-0.41.5-1.9-2.8-1.00.30.3-0.32.5
Distance traveled after self-admin0.61.13.7-0.60.90.8-1.1-1.8-0.30.60.60.31.9
Extensor digitorum longus weight1.14.511.23.3-1.0-2.72.52.02.31.91.91.50.4
Bone: elastic displacement0.50.61.30.60.7-0.40.2-0.50.61.01.00.81.1
Bone: elastic work0.50.72.01.1-0.90.0-0.4-1.10.10.90.90.11.4
Bone: endosteal estimation0.30.81.71.0-0.1-1.21.31.31.00.50.50.6-0.4
Bone: endosteal perimeter1.02.54.32.00.2-2.11.91.51.91.61.61.50.3
Epididymis fat weight4.321.552.07.2-4.2-6.05.96.14.22.32.31.9-2.3
Delta time in closed arm before/after self-admin0.70.71.3-0.7-0.41.1-1.1-0.9-1.0-0.7-0.7-0.80.1
Delta time in open arm before/after self-admin1.51.74.50.51.3-1.51.92.11.30.30.31.1-1.4
Diff in mean of infusions in LGA sessions0.50.91.60.60.7-1.31.31.11.20.80.80.9-0.4
Delay discount exponential model param2.22.94.7-2.2-0.81.7-1.5-0.5-1.8-2.1-2.1-1.8-1.5
Extinction: sum of active levers before priming1.72.63.81.80.9-1.81.81.21.71.91.91.90.3
Active lever presses in extinction session 60.90.91.61.30.2-1.01.00.61.01.11.11.10.0
Bone: final force0.81.47.81.2-2.8-0.30.30.9-0.4-0.7-0.7-1.1-1.1
Bone: final moment0.81.26.51.2-2.5-0.40.41.0-0.2-0.6-0.6-1.0-1.1
Food consumed during 24 hour testing period0.40.81.2-1.1-0.11.0-0.9-0.4-1.0-1.0-1.0-1.0-0.7
Glucose1.72.65.12.3-0.1-2.22.01.71.91.41.41.40.2
Heart weight1.32.18.42.1-2.9-1.01.01.70.2-0.4-0.4-0.7-1.6
Delay discount hyperbolic model param2.43.15.1-2.2-0.81.7-1.5-0.4-1.9-2.3-2.3-1.9-1.7
Intermittent access intake day 1-15 change0.10.81.30.31.1-0.50.3-0.70.91.11.11.11.1
Intermittent access intake escalation0.10.51.4-0.01.2-0.50.3-0.50.80.90.90.90.7
Intermittent access intake escalation 20.10.10.3-0.40.40.1-0.1-0.50.10.30.30.30.5
Intermitt. access day 1 inactive lever presses0.22.45.10.81.9-1.92.12.31.70.70.71.3-1.0
Intermitt. access day 15 inactive lever presses0.10.61.21.00.1-1.11.10.90.90.60.60.7-0.0
Intermitt. access escalation Index0.10.21.4-0.71.20.10.00.20.1-0.1-0.10.3-0.6
Intermittent access day 1 total infusions0.10.20.6-0.00.6-0.0-0.0-0.30.20.50.50.40.8
Intermittent access day 15 total infusions0.41.02.5-0.01.6-0.60.4-0.50.91.21.21.21.1
Intermittent access terminal intake (last 3 days)0.50.91.70.21.3-0.70.6-0.21.01.21.21.21.0
Intermittent access total infusions0.30.30.9-0.20.9-0.30.2-0.30.50.60.60.60.7
Intermittent access day 1 locomotion0.61.14.10.40.80.1-0.4-1.30.41.21.20.82.0
Intermittent access day 15 total locomotion0.51.82.61.11.1-1.51.40.61.61.61.61.50.8
Intermittent access total locomotion0.60.73.10.40.30.1-0.3-1.10.31.11.10.61.8
Intermittent access standard deviation0.52.84.31.51.6-1.81.70.61.91.91.92.11.1
Left kidney weight0.54.228.23.2-5.3-0.60.30.6-0.4-0.3-0.3-1.6-0.6
Right kidney weight0.64.024.83.6-5.0-0.80.40.30.00.40.4-1.00.1
Cocaine induced anxiety1.23.24.8-2.1-0.62.2-2.2-1.7-2.0-1.8-1.8-1.9-0.5
Post-drug Anxiety1.31.52.3-0.7-1.50.9-0.8-0.0-1.2-1.5-1.5-1.5-1.5
Baseline Anxiety1.11.94.61.6-0.1-1.82.02.11.40.60.61.0-1.0
Tail length0.20.81.60.80.6-1.21.21.01.10.80.81.0-0.3
Length with tail0.41.94.41.7-1.0-1.81.92.11.30.40.40.5-1.3
Length without tail0.73.59.42.2-1.2-2.42.63.11.60.30.30.6-1.8
Times rat made contact with spout0.00.00.10.1-0.30.0-0.10.0-0.1-0.1-0.1-0.2-0.0
Lifetime Intake0.10.10.3-0.50.60.2-0.2-0.50.00.20.20.10.6
Liver weight, left1.93.39.83.1-2.5-2.22.02.01.51.01.00.3-0.6
Liver weight, right0.71.14.72.0-2.2-0.80.50.30.50.80.8-0.00.2
Locomotor activity0.00.10.20.20.2-0.0-0.0-0.10.20.40.40.40.4
Locomotor testing distance0.20.51.8-0.4-0.10.8-1.0-1.3-0.50.10.1-0.11.1
Locomotor testing rearing0.20.93.00.50.7-0.3-0.0-0.90.61.21.20.91.7
Locomotion in novel chamber1.11.42.6-0.7-0.91.5-1.6-1.4-1.4-1.0-1.0-1.40.2
Locomotion in novel chamber post-restriction0.41.33.5-0.4-1.01.3-1.6-1.9-1.2-0.6-0.6-1.20.9
Fecal boli incidents, locomotor time 10.00.10.4-0.1-0.40.1-0.10.2-0.2-0.4-0.4-0.3-0.6
Change in fecal boli incidents, locomotor task0.60.61.90.1-1.40.3-0.30.2-0.6-1.0-1.0-1.0-0.6
Time >=10cm from walls, locomotor time 10.40.50.8-0.90.00.7-0.6-0.1-0.8-0.9-0.9-0.7-0.5
Bouts of movement, locomotor time 11.41.82.91.11.4-1.71.71.31.71.21.21.50.3
Total resting periods, locomotor time 10.91.11.60.91.0-1.31.20.91.30.90.91.10.3
Rest time, locomotor task time 10.60.92.1-0.2-1.51.0-1.1-0.8-1.1-0.9-0.9-1.2-0.1
Distance moved, locomotor task time 10.20.61.30.50.8-0.60.60.10.81.21.21.00.6
Vertical activity count, locomotor time 10.00.30.60.6-0.0-0.20.1-0.30.30.80.80.50.7
Time >=10cm from walls, locomotor time 20.51.44.0-0.1-2.00.9-0.8-0.1-1.2-1.3-1.3-1.6-1.1
Bouts of movement, locomotor time 20.41.35.5-0.22.3-0.50.5-0.20.91.21.21.31.2
Total resting periods, locomotor time 20.41.76.0-0.02.4-0.70.6-0.21.21.51.51.61.5
Rest time, locomotor task time 20.20.31.10.10.6-0.20.1-0.50.50.70.70.71.1
Distance moved, locomotor task time 20.40.51.2-0.4-1.10.7-0.6-0.1-0.9-0.7-0.7-1.0-0.7
Vertical activity count, locomotor time 20.30.61.8-0.2-1.30.6-0.6-0.1-0.8-0.9-0.9-1.1-0.7
Light reinforcement 10.20.71.3-0.6-1.00.9-1.0-1.1-0.9-0.5-0.5-1.00.4
Light reinforcement 20.61.32.2-1.3-0.61.5-1.5-1.2-1.4-1.0-1.0-1.3-0.1
Bone: marrow area0.30.81.71.0-0.2-1.21.21.30.90.50.50.6-0.5
Bone: maximum diameter1.63.27.02.1-0.4-2.42.52.61.91.01.01.2-1.0
Bone: maximum force0.81.68.30.7-2.90.1-0.10.7-0.8-1.1-1.1-1.5-1.4
Bone: maximum moment0.81.46.90.7-2.60.00.00.8-0.7-1.0-1.0-1.4-1.4
Mean time between licks in bursts0.10.71.9-0.91.4-0.30.71.20.3-0.6-0.60.3-1.3
Mean num. licks in bursts0.41.24.11.1-0.1-0.2-0.2-1.20.51.41.40.82.0
Cd content in liver4.44.98.0-2.2-1.52.8-2.8-2.4-2.6-2.0-2.0-2.3-0.1
Co content in liver1.72.03.5-0.4-1.91.8-1.8-1.5-1.8-1.1-1.1-1.7-0.2
Cu content in liver0.20.20.8-0.40.20.6-0.7-0.9-0.5-0.1-0.1-0.20.4
Fe content in liver0.81.03.70.4-0.6-0.81.11.90.3-0.7-0.7-0.2-1.8
K content in liver0.80.82.00.41.4-0.60.50.00.91.11.11.20.8
Mg content in liver2.02.23.50.81.9-0.90.7-0.41.41.91.91.81.9
Mn content in liver0.50.51.11.10.2-0.60.40.00.71.01.00.70.7
Na content in liver2.12.34.11.31.5-1.31.10.31.62.02.01.91.5
Rb content in liver0.80.91.60.71.1-0.90.90.61.11.01.01.30.5
Se content in liver0.30.41.1-0.6-0.40.5-0.40.1-0.6-0.8-0.8-0.7-1.0
Sr content in liver0.90.82.5-1.10.51.1-1.2-1.6-0.7-0.2-0.2-0.40.6
Zn content in liver1.01.14.1-0.20.90.5-0.8-1.90.00.90.90.62.0
Bone: minimum diameter0.81.43.21.8-1.8-1.41.41.70.80.20.20.0-0.9
Time in familiar zone, hab. session 10.91.02.51.6-0.5-0.80.5-0.30.91.41.40.71.3
Time in novel zone, hab. session 10.70.82.4-1.20.80.10.31.1-0.2-1.0-1.0-0.2-1.5
Total zone transitions, hab. session 10.20.31.31.0-1.2-0.1-0.1-0.40.10.40.4-0.10.7
Total locomotion distance, hab. session 10.81.12.2-0.8-0.80.7-0.40.5-1.0-1.5-1.5-1.2-1.5
Locomotion velocity, hab. session 10.81.12.1-0.8-0.90.8-0.60.3-1.1-1.5-1.5-1.3-1.3
Time in familiar zone, hab. session 20.70.82.30.30.9-1.11.31.50.90.20.20.6-0.9
Time in novel zone, hab. session 20.50.61.7-0.2-0.80.9-1.1-1.3-0.8-0.2-0.2-0.60.8
Total zone transitions, hab. session 20.30.31.00.7-0.1-0.20.0-0.50.40.80.80.41.0
Total locomotion distance, hab. session 20.10.10.60.4-0.8-0.0-0.00.2-0.2-0.2-0.2-0.4-0.2
Locomotion velocity, hab. session 20.10.10.30.5-0.6-0.10.10.10.00.10.1-0.10.1
Novel to familiar place preference ratio0.70.92.7-0.7-0.60.3-0.10.8-0.7-1.4-1.4-0.9-1.7
Novelty place preference0.50.62.0-0.6-0.40.20.00.8-0.5-1.1-1.1-0.7-1.4
Time in novel zone, NPP test0.60.82.9-0.3-0.5-0.10.41.3-0.2-1.1-1.1-0.6-1.7
Total zone transitions, NPP test0.10.10.40.5-0.60.0-0.2-0.3-0.10.10.1-0.20.4
Total locomotion distance, NPP test0.91.32.3-0.6-1.41.0-0.9-0.2-1.3-1.4-1.4-1.5-0.9
Locomotion velocity, NPP test1.31.93.2-0.9-1.41.5-1.4-0.8-1.7-1.5-1.5-1.8-0.7
Intraocular pressure0.61.03.60.9-0.3-1.01.31.90.6-0.1-0.10.3-1.6
Delta distance traveled before/after self-admin0.91.01.81.11.3-0.90.80.41.01.11.11.20.4
Delta ambulatory time before/after self-admin0.61.01.41.11.2-1.01.00.81.11.01.01.00.1
Parametrial fat weight6.314.934.25.9-2.7-5.15.04.93.82.42.42.0-1.4
Pavlov. Cond. lever latency0.40.41.8-0.41.3-0.60.70.70.70.20.20.7-0.4
Pavlov. Cond. magazine entry latency0.00.10.20.4-0.4-0.10.0-0.10.10.20.20.00.2
Pavlov. Cond. change in total contacts0.30.41.31.1-0.6-0.50.3-0.00.40.70.70.30.6
Pavlov. Cond. index score0.20.20.80.9-0.7-0.30.1-0.10.20.40.40.10.5
Pavlov. Cond. latency score0.10.10.50.7-0.7-0.1-0.0-0.20.00.30.3-0.00.5
Pavlov. Cond. lever contacts0.20.20.70.9-0.7-0.20.0-0.20.10.40.40.10.6
Pavlov. Cond. magazine entry number0.20.30.7-0.80.00.5-0.4-0.0-0.5-0.7-0.7-0.5-0.6
Pavlov. Cond. intertrial magazine entries1.41.76.80.1-2.60.8-0.8-0.2-1.2-1.3-1.3-1.7-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.90.9-0.7-0.30.2-0.00.20.40.40.10.4
Pavlov. Cond. response bias0.10.10.50.6-0.3-0.1-0.1-0.30.10.40.40.20.7
Pavlov. Cond. lever latency0.50.72.5-0.5-0.31.0-1.2-1.6-0.7-0.0-0.0-0.51.0
Pavlov. Cond. magazine entry latency0.91.32.10.71.3-1.31.41.21.40.90.91.40.0
Pavlov. Cond. change in total contacts0.20.61.60.30.8-0.91.11.30.80.30.30.7-0.6
Pavlov. Cond. index score0.61.02.30.70.7-1.31.41.51.10.50.50.9-0.6
Pavlov. Cond. latency score0.50.82.00.60.7-1.21.31.41.00.40.40.9-0.5
Pavlov. Cond. lever contacts0.20.31.30.5-0.1-0.70.81.10.4-0.0-0.00.2-0.8
Pavlov. Cond. magazine entry number0.70.91.5-0.8-0.81.2-1.2-1.0-1.1-0.8-0.8-1.1-0.1
Pavlov. Cond. intertrial magazine entries0.10.31.80.7-1.3-0.20.10.1-0.1-0.0-0.0-0.5-0.1
Pavlov. Cond. lever-magazine prob. diff.0.50.81.80.70.7-1.21.31.31.00.60.60.9-0.4
Pavlov. Cond. response bias0.60.82.70.50.4-1.01.31.60.80.10.10.6-1.0
Time in closed arm before self-admin0.30.61.51.20.1-0.40.2-0.30.51.11.10.70.9
Time in closed arm after self-admin0.70.82.50.40.30.8-0.9-1.4-0.40.80.80.31.6
Time in open arm before self-admin1.51.85.2-2.3-0.01.3-1.2-0.5-1.3-1.7-1.7-1.4-0.5
Time in open arm after self-admin0.70.82.0-0.90.9-0.71.01.40.5-0.6-0.60.1-1.4
Bone: periosteal estimation0.61.54.51.7-2.1-1.31.31.70.6-0.0-0.0-0.3-1.2
Bone: periosteal perimeter1.73.47.82.8-1.1-2.42.32.11.91.51.51.2-0.1
Bone: post-yield work1.22.15.3-0.7-1.70.5-0.21.0-1.1-1.8-1.8-1.7-2.3
Progressive ratio test 1 active lever presses0.50.82.5-0.11.60.0-0.1-0.80.41.01.01.01.5
Progressive ratio test 1 breakpoint0.50.82.3-0.11.50.1-0.1-0.80.41.01.00.91.4
Progressive ratio test 1 inactive lever presses0.10.40.70.40.8-0.60.70.60.70.60.60.70.3
Progressive ratio test 2 active lever presses0.71.01.80.80.9-0.90.7-0.11.01.31.31.11.1
Progressive ratio test 2 breakpoint0.81.01.70.70.9-0.90.7-0.11.11.31.31.11.0
Progressive ratio test 2 inactive lever presses0.10.20.4-0.60.30.10.10.6-0.2-0.5-0.5-0.3-0.6
Incentive Sensitization - Responses0.51.52.21.40.6-1.51.30.51.51.51.51.30.6
Incentive Sensitization - Breakpoint0.71.52.31.40.7-1.51.40.61.51.41.41.30.5
Sum of active levers in priming session hrs 5-62.01.92.90.81.5-1.61.61.11.71.41.41.70.0
Progressive ratio0.41.23.5-1.91.11.3-1.0-0.3-1.1-1.2-1.2-0.7-0.5
Food seeking constrained by brief footshock0.10.10.2-0.50.30.4-0.3-0.3-0.3-0.3-0.3-0.0-0.1
Seeking ratio, punishment vs. effort0.51.22.91.7-0.7-0.80.5-0.50.91.51.50.91.2
Retroperitoneal fat weight6.328.173.78.6-6.0-6.66.46.84.42.42.41.5-2.8
Reaction time number correct0.62.23.61.01.7-1.51.40.61.71.71.71.91.2
Reaction time mean minus median0.42.94.61.71.2-1.71.50.41.92.12.12.11.5
Reaction time mean minus median AUC0.85.39.51.92.0-1.71.4-0.42.23.13.12.82.9
Reaction time num false alarms0.50.82.50.1-1.60.9-1.0-0.7-1.1-0.6-0.6-1.0-0.0
Reaction time num false alarms AUC0.30.61.90.2-1.40.9-1.0-0.9-0.9-0.3-0.3-0.80.4
Reaction time trials correct on left0.62.23.61.01.7-1.51.40.61.71.71.71.91.2
Reaction time trials on left0.72.54.11.11.8-1.61.50.71.81.81.82.01.2
Reaction time mean2.14.78.01.32.5-1.61.3-0.32.22.82.82.82.5
Reaction time mean AUC2.35.69.41.42.8-1.71.4-0.42.33.13.13.02.8
Median of all reaction times2.84.57.61.02.6-1.31.0-0.62.02.82.82.72.7
Reaction time omissions2.94.87.21.81.8-2.52.41.42.62.42.42.71.0
Reaction time false alarm rate1.52.15.0-0.4-2.21.5-1.5-0.8-1.7-1.3-1.3-1.8-0.6
Reaction time premature initiation rate0.30.41.80.4-1.30.6-0.7-0.8-0.6-0.1-0.1-0.50.4
Reaction time premature initiations0.20.51.11.0-0.3-0.30.2-0.40.40.90.90.61.1
Std. dev. reaction times1.34.57.02.21.4-2.21.90.62.32.62.62.61.8
Reaction time trials completed0.72.54.11.11.8-1.61.50.71.81.81.82.01.2
Reaction time trials AUC0.62.23.71.11.6-1.51.40.71.71.71.71.91.1
Run reversals in cocaine runway, females0.20.20.30.40.5-0.50.50.50.50.40.40.6-0.0
Run reversals in cocaine runway, males0.30.31.00.1-0.50.5-0.6-1.0-0.30.30.30.11.0
Latency to leave start box in cocaine runway1.82.46.90.62.6-1.01.00.21.51.81.82.11.3
Latency to leave start box in cocaine runway, F1.01.22.30.61.5-1.01.00.51.21.31.31.50.6
Latency to leave start box in cocaine runway, M1.21.12.60.61.6-0.40.3-0.40.81.31.31.31.4
Std. dev. time between licks in bursts1.01.83.3-1.8-0.01.1-0.70.3-1.3-1.8-1.8-1.3-1.7
Total sessions with >9 infusions0.30.40.8-0.7-0.00.9-0.9-0.7-0.8-0.3-0.3-0.50.5
Short access day 1 total inactive lever presses0.40.91.5-1.20.10.8-0.40.7-1.0-1.2-1.2-0.8-1.1
Short access day 10 total inactive lever presses0.10.52.01.4-0.6-0.60.50.50.50.70.70.40.2
Short access day 1 total infusions0.10.10.4-0.1-0.00.4-0.4-0.4-0.30.40.40.20.6
Short access day 10 total infusions0.61.02.3-1.20.81.2-1.3-1.5-0.8-0.0-0.0-0.11.2
Short access total infusions0.50.71.4-1.10.31.2-1.2-1.1-0.9-0.4-0.4-0.40.6
Short access day 1 locomotion0.50.91.90.51.3-0.30.3-0.20.61.31.31.21.4
Short access day 10 total locomotion0.20.93.60.70.50.3-0.4-1.00.21.21.20.91.9
Short access total locomotion0.81.13.8-0.60.51.1-1.3-1.8-0.60.50.50.22.0
One hour access (0.3 mA shock)1.01.22.8-0.11.7-1.31.41.01.40.70.71.2-0.0
Compulsive drug intake0.50.81.71.00.0-1.11.21.30.90.60.60.7-0.6
One hour access (shock baseline)0.10.41.6-1.11.30.1-0.1-0.50.10.00.00.20.5
Social response proportion0.50.62.01.2-1.40.0-0.3-0.6-0.00.60.6-0.11.0
Social responses0.60.82.71.6-1.5-1.00.90.90.60.40.40.1-0.2
Social time1.52.34.71.21.1-1.10.8-0.51.52.02.01.72.2
Soleus weight3.510.318.14.10.5-3.12.30.23.44.34.33.33.6
Bone: stiffness0.91.55.50.2-2.40.3-0.20.7-0.9-1.3-1.3-1.5-1.6
Tibialis anterior weight1.55.27.92.41.3-2.82.51.52.82.52.52.51.3
Time to tail flick, vehicle, before self-admin1.01.22.4-0.9-1.00.8-0.60.2-1.1-1.5-1.5-1.5-1.2
Time to tail flick, vehicle, after self-admin0.10.21.00.1-1.0-0.20.20.40.0-0.2-0.2-0.3-0.6
Time to tail flick, test, before self-admin1.01.23.8-0.5-0.11.2-1.4-1.9-0.80.40.4-0.11.8
Time to tail flick, test, after self-admin0.50.51.5-0.81.0-0.20.40.90.1-0.6-0.6-0.0-1.2
Delta time to tail flick, vehicle, before/after SA1.51.62.61.20.6-1.61.51.01.61.31.31.4-0.0
Delta time to tail flick, test, before/after SA0.60.83.3-0.40.3-0.40.71.30.1-1.0-1.0-0.4-1.8
Tibia length0.10.31.90.4-1.40.2-0.3-0.0-0.5-0.4-0.4-0.7-0.3
Ambulatory time before self-admin0.51.75.3-1.1-0.61.5-1.7-2.3-1.1-0.0-0.0-0.51.8
Ambulatory time after self-admin0.40.72.5-0.20.70.4-0.6-1.30.00.80.80.51.6
Bone: tissue strength0.10.10.2-0.50.50.10.00.2-0.0-0.3-0.30.0-0.5
Total heroin consumption2.52.94.92.00.3-2.22.21.71.91.71.71.7-0.3
Bone: trabecular number0.71.34.60.8-0.9-1.11.42.20.5-0.5-0.5-0.2-1.8
Bone: trabecular spacing0.30.51.8-1.21.40.6-0.5-0.6-0.3-0.2-0.20.20.3
Bone: trabecular thickness1.52.15.02.2-1.3-1.91.82.01.30.70.70.5-0.7
Bone: trabecular tissue density0.61.02.6-0.51.40.4-0.6-1.50.20.90.90.81.6
Water consumed over 24 hours0.10.10.4-0.30.10.5-0.5-0.6-0.3-0.0-0.0-0.20.4
Number of responses in last shaping day0.10.10.2-0.40.20.2-0.3-0.5-0.10.20.20.00.4