Hub : Genes

Eno4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Eno4 0.09 0.06 2.4e-09 0.06 0.06 0.07 0.06 9.1e-08 1.1e-07 1.7e-08 1.7e-07
2 NAcc gene expression Eno4 0.1 0.1 5.8e-03 0 0 -0 0 1.3e-01 1.6e-01 7.1e-01 3.3e-01
3 IC intron excision ratio chr1_268094929_268095751 0.12 0.08 6.9e-03 -0 0.01 -0.01 -0 6.2e-01 1.1e-01 7.2e-01 5.7e-01
4 IC intron excision ratio chr1_268082758_268084457 0.15 0.08 6.4e-04 0.06 0.07 0.05 0.06 1.1e-03 7.9e-04 3.2e-03 1.7e-03
5 Brain isoform ratio XR_005500392.2 0.04 0.03 7.0e-03 0.03 0.02 0.01 0.02 1.7e-03 3.3e-03 3.3e-02 5.1e-03
6 Adipose isoform ratio NM_001134505.1 0.03 0.03 5.3e-03 0.01 0.01 0.01 0.01 2.7e-02 1.2e-02 2.0e-02 2.9e-02
7 Adipose alternative TSS XM_006231669.5 0.06 0.04 7.3e-07 0.05 0.04 0.04 0.04 4.9e-06 1.2e-05 3.9e-05 2.2e-05
8 Adipose isoform ratio XR_005500392.2 0.07 0.04 5.5e-07 0.05 0.04 0.05 0.04 5.6e-06 9.8e-06 7.5e-06 8.0e-06
9 NAcc isoform ratio XM_039103299.2 0.13 0.12 1.3e-04 0.01 0.03 0.02 0.02 3.6e-03 9.7e-05 1.9e-04 1.3e-04
10 Adipose alternative TSS XM_039103299.2 0.06 0.04 9.6e-07 0.05 0.04 0.04 0.04 6.5e-06 1.6e-05 5.0e-05 2.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.71.24.3-1.00.9-1.21.4-2.10.60.40.4-0.11.5
Area under the delay curve2.22.54.4-2.1-0.6-1.61.4-0.51.7-2.0-2.01.7-1.4
BMI with tail4.214.447.1-6.95.2-4.54.0-3.63.0-2.3-2.30.90.4
BMI without tail2.67.826.7-5.24.8-3.02.6-2.41.8-1.4-1.40.10.5
Body weight4.017.648.9-7.04.9-5.34.9-4.93.6-2.2-2.21.31.6
Weight adjusted by age0.91.35.9-2.32.4-0.80.6-0.40.4-0.7-0.70.1-0.2
Bone surface0.40.82.3-0.61.2-0.70.8-1.50.10.60.6-0.41.4
Bone volume0.81.53.3-1.71.1-1.61.6-1.81.1-0.4-0.40.40.7
Breakpoint value in progressive ratio session2.42.94.5-1.1-2.0-2.12.1-1.72.0-1.6-1.61.90.4
Number of licking bursts0.71.13.41.10.20.30.0-1.0-0.71.51.5-1.01.9
Context. condit. distance diff. score0.91.11.80.61.31.2-1.10.7-1.31.11.1-1.30.4
Locomotion velocity, session 10.10.10.20.4-0.10.4-0.40.3-0.30.20.2-0.20.2
Locomotion distance, session 11.01.22.41.10.41.5-1.61.5-1.30.80.8-1.0-0.3
Locomotion velocity, session 22.02.44.41.80.42.1-2.11.8-1.81.21.2-1.4-0.0
Locomotion distance, session 21.01.42.50.41.61.4-1.51.3-1.40.80.8-1.4-0.2
Locomotion velocity, session 30.70.81.51.10.21.2-1.21.1-1.10.70.7-0.8-0.2
Locomotion distance, session 31.31.42.90.81.01.5-1.71.7-1.40.70.7-1.1-0.7
Stereotopy head waving bouts, day 30.20.21.10.4-1.10.1-0.10.40.2-0.4-0.40.5-0.6
Stereotopy head waving duration, day 30.20.32.10.6-1.4-0.10.2-0.20.3-0.2-0.20.5-0.1
Locomotion velocity, session 70.80.82.00.31.40.8-0.80.4-1.01.01.0-1.20.5
Locomotion distance, session 70.91.22.80.31.71.2-1.31.0-1.30.90.9-1.3-0.0
Stereotopy head waving bouts, day 70.10.20.3-0.5-0.2-0.50.5-0.30.5-0.4-0.40.4-0.1
Stereotopy head waving duration, day 71.11.42.0-0.9-1.2-1.41.4-1.01.4-1.1-1.11.4-0.2
Locomotion velocity, session 82.32.84.41.90.81.8-1.50.5-1.92.12.1-1.91.5
Locomotion distance, session 85.07.311.02.22.53.0-2.91.6-3.33.03.0-3.31.4
Degree of sensitization distance0.30.30.9-0.50.4-0.60.7-1.00.40.10.10.00.7
Degree of sensitization stereotypy0.40.51.1-1.00.5-0.90.9-1.00.7-0.3-0.30.30.4
Conditioned locomotion0.20.30.6-0.3-0.7-0.60.5-0.20.7-0.5-0.50.6-0.4
Cocaine response after cond. corrected2.73.28.61.9-0.12.4-2.62.9-1.80.70.7-1.1-1.4
Cocaine response after cond. not corrected2.52.96.62.2-0.62.3-2.32.6-1.70.90.9-1.0-0.9
Cocaine response before conditioning0.40.51.50.4-0.9-0.50.8-1.20.40.30.30.41.2
Saline control response0.20.20.80.20.20.6-0.70.9-0.5-0.0-0.0-0.2-0.6
Bone: connectivity density0.40.61.9-0.10.6-0.40.6-1.3-0.00.80.8-0.41.4
Bone: cortical apparent density2.33.17.62.1-0.52.4-2.52.8-1.80.80.8-1.0-1.1
Bone: cortical area1.42.28.1-1.82.8-1.11.2-2.00.30.40.4-0.81.7
Bone: cortical porosity0.30.30.6-0.4-0.4-0.80.8-0.80.7-0.4-0.40.50.3
Bone: cortical porosity0.80.92.3-1.0-0.1-1.31.3-1.51.0-0.4-0.40.60.7
Bone: cortical thickness1.62.614.2-1.03.80.3-0.4-0.5-1.11.31.3-2.01.4
Bone: cortical thickness0.60.74.8-1.42.2-0.2-0.10.1-0.1-0.3-0.3-0.5-0.3
Bone: cortical tissue density2.33.17.52.2-0.72.4-2.52.7-1.80.80.8-1.0-1.1
Condit. Reinf. active minus inactive responses1.21.32.21.20.71.2-1.00.3-1.31.51.5-1.31.0
Condit. Reinf. active-inactive response ratio0.60.61.51.2-0.40.8-0.50.0-0.71.01.0-0.60.7
Condit. Reinf. active responses1.51.84.70.32.20.8-0.6-0.3-1.31.61.6-1.71.5
Condit. Reinf. inactive responses1.41.77.4-0.62.70.2-0.1-0.7-0.81.31.3-1.61.5
Incentive salience index mean1.41.72.51.01.31.4-1.30.7-1.61.51.5-1.60.7
Condit. Reinf. lever presses0.50.71.20.31.10.9-0.90.7-1.00.80.8-1.00.0
Condit. Reinf. active minus inactive responses0.81.13.0-0.8-0.5-1.31.5-1.71.1-0.4-0.40.80.8
Condit. Reinf. active-inactive response ratio0.40.51.2-0.8-0.1-1.01.0-1.10.7-0.3-0.30.50.4
Condit. Reinf. active responses1.21.74.9-1.3-0.1-1.71.9-2.21.3-0.5-0.50.91.0
Condit. Reinf. inactive responses0.60.82.0-0.9-0.1-1.21.3-1.40.9-0.4-0.40.70.6
Condit. Reinf. lever presses0.40.61.6-1.00.4-1.01.1-1.30.7-0.3-0.30.40.6
Condit. Reinf. lever reinforcers received0.71.03.6-0.8-0.0-1.21.5-1.90.9-0.1-0.10.51.2
Conditioned reinforcement - actives0.91.52.81.5-0.71.7-1.71.6-1.30.70.7-0.8-0.9
Conditioned reinforcement - inactives0.30.42.00.5-1.4-0.40.6-0.70.5-0.3-0.30.6-0.1
Conditioned locomotion1.82.44.71.7-0.22.2-2.22.0-1.81.01.0-1.2-1.0
Patch foraging indifference point 0 sec0.61.15.4-1.62.3-0.70.6-0.90.10.10.1-0.60.9
Patch foraging indifference point AUC0.40.51.2-0.90.3-1.11.0-1.00.8-0.3-0.30.30.5
Delay disc. indifference point, 0s delay0.30.31.2-0.61.10.1-0.30.6-0.1-0.3-0.3-0.2-0.7
Delay disc. indifference point, 16s delay1.71.83.0-1.7-0.7-1.41.2-0.51.4-1.7-1.71.5-1.2
Delay disc. indifference point, 2s delay1.31.43.1-1.2-0.4-0.60.30.80.9-1.7-1.71.3-1.7
Delay disc. indifference point, 24s delay1.21.32.6-1.6-0.2-1.41.3-1.01.3-1.2-1.21.1-0.3
Delay disc. indifference point, 4s delay1.81.83.1-1.7-0.7-1.31.1-0.21.4-1.8-1.81.5-1.4
Delay disc. indifference point, 8s delay1.72.03.1-1.7-1.0-1.51.3-0.51.6-1.8-1.81.6-1.2
Indifference point function ln k0.20.40.60.30.60.8-0.80.5-0.80.60.6-0.70.1
Indifference point function log k0.20.40.60.30.60.8-0.80.5-0.80.60.6-0.70.1
Patch foraging total patch changes 0 sec0.71.46.4-1.92.5-0.80.8-1.10.20.10.1-0.61.0
Patch foraging total patch changes 12 sec0.81.13.4-1.51.8-1.00.9-1.30.40.10.1-0.41.1
Patch foraging total patch changes 18 sec1.21.83.6-1.90.7-1.91.9-1.81.4-0.6-0.60.60.8
Patch foraging total patch changes 24 sec0.50.92.2-1.10.7-1.31.3-1.50.9-0.1-0.10.21.0
Patch foraging total patch changes 6 sec1.01.65.1-1.52.3-1.01.1-1.70.40.30.3-0.51.7
Patch foraging time to switch 0 sec0.51.05.41.2-2.30.2-0.10.60.4-0.6-0.61.1-1.0
Patch foraging water rate 0 sec0.71.48.1-1.82.8-0.50.3-0.7-0.10.30.3-0.90.9
Patch foraging water rate 12 sec0.51.13.9-1.42.0-0.80.9-1.30.20.30.3-0.61.3
Patch foraging water rate 18 sec0.20.42.0-0.61.40.4-0.50.6-0.50.10.1-0.6-0.2
Patch foraging water rate 24 sec0.50.72.7-1.61.6-0.40.10.30.3-0.7-0.70.1-0.8
Patch foraging water rate 6 sec0.30.42.1-1.31.5-0.30.20.10.1-0.4-0.4-0.1-0.2
Seeking ratio, delayed vs. immediate footshock1.92.44.42.1-0.22.0-1.91.3-1.71.61.6-1.30.4
Distance traveled before self-admin1.72.27.81.10.41.5-1.92.8-1.0-0.3-0.3-0.3-2.5
Distance traveled after self-admin0.91.13.70.6-0.90.8-1.11.8-0.3-0.6-0.60.3-1.9
Extensor digitorum longus weight1.14.511.1-3.31.0-2.72.5-2.02.3-1.9-1.91.5-0.4
Bone: elastic displacement0.50.61.3-0.6-0.7-0.40.20.50.6-1.0-1.00.8-1.1
Bone: elastic work0.50.72.0-1.10.90.0-0.41.10.1-0.9-0.90.1-1.4
Bone: endosteal estimation0.40.81.7-1.00.1-1.21.3-1.31.0-0.5-0.50.60.4
Bone: endosteal perimeter1.22.54.3-2.0-0.2-2.11.9-1.51.9-1.6-1.61.5-0.3
Epididymis fat weight6.321.551.6-7.24.2-6.05.9-6.14.2-2.3-2.31.92.3
Delta time in closed arm before/after self-admin0.70.71.30.70.41.1-1.10.9-1.00.70.7-0.8-0.1
Delta time in open arm before/after self-admin1.71.74.5-0.5-1.3-1.51.9-2.11.3-0.3-0.31.11.4
Diff in mean of infusions in LGA sessions0.70.91.6-0.6-0.7-1.31.3-1.11.2-0.8-0.80.90.4
Delay discount exponential model param2.62.94.82.20.81.7-1.50.5-1.82.12.1-1.81.5
Extinction: sum of active levers before priming2.32.63.8-1.8-0.9-1.81.8-1.21.7-1.9-1.91.9-0.3
Active lever presses in extinction session 60.90.91.6-1.3-0.2-1.01.0-0.61.0-1.1-1.11.1-0.0
Bone: final force0.91.47.8-1.22.8-0.30.3-0.9-0.40.70.7-1.11.1
Bone: final moment0.81.26.5-1.22.5-0.40.4-1.0-0.20.60.6-1.01.1
Food consumed during 24 hour testing period0.60.81.21.10.11.0-0.90.4-1.01.01.0-1.00.7
Glucose1.72.65.1-2.30.1-2.22.0-1.71.9-1.4-1.41.4-0.2
Heart weight1.42.18.4-2.12.9-1.01.0-1.70.20.40.4-0.71.6
Delay discount hyperbolic model param2.83.15.12.30.81.7-1.50.4-1.92.32.3-1.91.7
Intermittent access intake day 1-15 change0.40.81.3-0.3-1.1-0.50.30.70.9-1.1-1.11.1-1.1
Intermittent access intake escalation0.30.51.40.0-1.2-0.50.30.50.8-0.9-0.90.9-0.7
Intermittent access intake escalation 20.10.10.30.3-0.40.1-0.10.50.1-0.3-0.30.3-0.5
Intermitt. access day 1 inactive lever presses0.62.45.1-0.8-1.9-1.92.1-2.31.7-0.7-0.71.31.0
Intermitt. access day 15 inactive lever presses0.30.61.2-1.0-0.1-1.11.1-0.90.9-0.6-0.60.70.0
Intermitt. access escalation Index0.20.21.40.7-1.20.10.0-0.20.10.10.10.30.6
Intermittent access day 1 total infusions0.10.20.60.0-0.6-0.0-0.00.30.2-0.5-0.50.4-0.8
Intermittent access day 15 total infusions0.61.02.50.0-1.6-0.60.40.50.9-1.2-1.21.2-1.1
Intermittent access terminal intake (last 3 days)0.70.91.7-0.2-1.3-0.70.60.21.0-1.2-1.21.2-1.0
Intermittent access total infusions0.30.30.90.2-0.9-0.30.20.30.5-0.6-0.60.6-0.7
Intermittent access day 1 locomotion0.81.14.1-0.4-0.80.1-0.41.30.4-1.2-1.20.8-2.0
Intermittent access day 15 total locomotion1.01.82.6-1.1-1.1-1.51.4-0.61.6-1.6-1.61.5-0.8
Intermittent access total locomotion0.60.73.1-0.4-0.30.1-0.31.10.3-1.1-1.10.6-1.8
Intermittent access standard deviation1.32.84.3-1.5-1.6-1.81.7-0.61.9-1.9-1.92.1-1.1
Left kidney weight0.94.228.2-3.25.3-0.60.3-0.6-0.40.30.3-1.60.6
Right kidney weight0.94.024.8-3.65.0-0.80.4-0.30.0-0.4-0.4-1.0-0.1
Cocaine induced anxiety2.23.24.82.20.62.2-2.21.7-2.01.81.8-1.90.5
Post-drug Anxiety1.41.52.30.71.50.9-0.80.0-1.21.51.5-1.51.5
Baseline Anxiety1.61.94.6-1.60.1-1.82.0-2.11.4-0.6-0.61.01.0
Tail length0.20.81.6-0.8-0.6-1.21.2-1.01.1-0.8-0.81.00.3
Length with tail0.41.94.4-1.71.0-1.81.9-2.11.3-0.4-0.40.51.3
Length without tail1.13.59.4-2.21.2-2.42.6-3.11.6-0.3-0.30.61.8
Times rat made contact with spout0.00.00.1-0.10.30.0-0.1-0.0-0.10.10.1-0.20.0
Lifetime Intake0.10.10.30.5-0.60.2-0.20.50.0-0.2-0.20.1-0.6
Liver weight, left2.03.39.7-3.12.5-2.22.0-2.01.5-1.0-1.00.30.6
Liver weight, right0.71.14.7-2.02.2-0.80.5-0.30.5-0.8-0.8-0.0-0.2
Locomotor activity0.00.10.2-0.2-0.2-0.0-0.00.10.2-0.4-0.40.4-0.4
Locomotor testing distance0.30.51.80.40.10.8-1.01.3-0.5-0.1-0.1-0.1-1.1
Locomotor testing rearing0.40.93.0-0.5-0.7-0.3-0.00.90.6-1.2-1.20.9-1.7
Locomotion in novel chamber1.11.42.60.70.91.5-1.61.4-1.41.01.0-1.4-0.2
Locomotion in novel chamber post-restriction0.81.33.50.41.01.3-1.61.9-1.20.60.6-1.2-0.9
Fecal boli incidents, locomotor time 10.10.10.40.10.40.1-0.1-0.2-0.20.40.4-0.30.6
Change in fecal boli incidents, locomotor task0.60.61.9-0.11.40.3-0.3-0.2-0.61.01.0-1.00.6
Time >=10cm from walls, locomotor time 10.40.50.80.9-0.00.7-0.60.1-0.80.90.9-0.70.5
Bouts of movement, locomotor time 11.61.82.9-1.1-1.4-1.71.7-1.31.7-1.2-1.21.5-0.3
Total resting periods, locomotor time 10.91.11.6-0.9-1.0-1.31.2-0.91.3-0.9-0.91.1-0.3
Rest time, locomotor task time 10.70.92.10.21.51.0-1.10.8-1.10.90.9-1.20.1
Distance moved, locomotor task time 10.40.61.3-0.5-0.8-0.60.6-0.10.8-1.2-1.21.0-0.6
Vertical activity count, locomotor time 10.10.30.6-0.60.0-0.20.10.30.3-0.8-0.80.5-0.7
Time >=10cm from walls, locomotor time 21.01.44.00.12.00.9-0.80.1-1.21.31.3-1.61.1
Bouts of movement, locomotor time 20.81.35.50.2-2.3-0.50.50.20.9-1.2-1.21.3-1.2
Total resting periods, locomotor time 21.01.76.00.0-2.4-0.70.60.21.2-1.5-1.51.6-1.5
Rest time, locomotor task time 20.30.31.1-0.1-0.6-0.20.10.50.5-0.7-0.70.7-1.1
Distance moved, locomotor task time 20.50.51.20.41.10.7-0.60.1-0.90.70.7-1.00.7
Vertical activity count, locomotor time 20.50.61.80.21.30.6-0.60.1-0.80.90.9-1.10.7
Light reinforcement 10.30.71.30.61.00.9-1.01.1-0.90.50.5-1.0-0.4
Light reinforcement 20.91.32.21.30.61.5-1.51.2-1.41.01.0-1.30.1
Bone: marrow area0.40.81.7-1.00.2-1.21.2-1.30.9-0.5-0.50.60.5
Bone: maximum diameter1.73.27.0-2.10.4-2.42.5-2.61.9-1.0-1.01.21.0
Bone: maximum force0.91.68.3-0.72.90.1-0.1-0.7-0.81.11.1-1.51.4
Bone: maximum moment0.81.46.9-0.72.60.00.0-0.8-0.71.01.0-1.41.4
Mean time between licks in bursts0.30.71.90.9-1.4-0.30.7-1.20.30.60.60.31.3
Mean num. licks in bursts0.81.24.1-1.10.1-0.2-0.21.20.5-1.4-1.40.8-2.0
Cd content in liver4.44.98.02.21.52.8-2.82.4-2.62.02.0-2.30.1
Co content in liver1.82.03.50.41.91.8-1.81.5-1.81.11.1-1.70.2
Cu content in liver0.20.20.80.4-0.20.6-0.70.9-0.50.10.1-0.2-0.4
Fe content in liver0.81.03.7-0.40.6-0.81.1-1.90.30.70.7-0.21.8
K content in liver0.80.82.0-0.4-1.4-0.60.5-0.00.9-1.1-1.11.2-0.8
Mg content in liver2.12.23.5-0.8-1.9-0.90.70.41.4-1.9-1.91.8-1.9
Mn content in liver0.50.51.1-1.1-0.2-0.60.4-0.00.7-1.0-1.00.7-0.7
Na content in liver2.22.34.1-1.3-1.5-1.31.1-0.31.6-2.0-2.01.9-1.5
Rb content in liver0.80.91.6-0.7-1.1-0.90.9-0.61.1-1.0-1.01.3-0.5
Se content in liver0.30.41.10.60.40.5-0.4-0.1-0.60.80.8-0.71.0
Sr content in liver0.90.82.51.0-0.51.1-1.21.6-0.70.20.2-0.4-0.6
Zn content in liver1.01.14.10.2-0.90.5-0.81.90.0-0.9-0.90.6-2.0
Bone: minimum diameter0.81.43.2-1.81.8-1.41.4-1.70.8-0.2-0.20.00.9
Time in familiar zone, hab. session 11.11.02.5-1.60.5-0.80.50.30.9-1.4-1.40.7-1.3
Time in novel zone, hab. session 10.80.82.41.2-0.80.10.3-1.1-0.21.01.0-0.21.5
Total zone transitions, hab. session 10.20.31.3-1.01.2-0.1-0.10.40.1-0.4-0.4-0.1-0.7
Total locomotion distance, hab. session 10.81.12.20.80.80.7-0.4-0.5-1.01.51.5-1.21.5
Locomotion velocity, hab. session 10.81.12.10.80.90.8-0.6-0.3-1.11.51.5-1.31.3
Time in familiar zone, hab. session 20.70.82.3-0.2-0.9-1.11.3-1.50.9-0.2-0.20.60.9
Time in novel zone, hab. session 20.60.61.70.20.80.9-1.11.3-0.80.20.2-0.6-0.8
Total zone transitions, hab. session 20.30.31.0-0.70.1-0.20.00.50.4-0.8-0.80.4-1.0
Total locomotion distance, hab. session 20.10.10.6-0.40.8-0.0-0.0-0.2-0.20.20.2-0.40.2
Locomotion velocity, hab. session 20.10.10.3-0.50.6-0.10.1-0.10.0-0.1-0.1-0.1-0.1
Novel to familiar place preference ratio0.90.92.70.70.60.3-0.1-0.8-0.71.41.4-0.91.7
Novelty place preference0.60.62.00.60.40.20.0-0.8-0.51.11.1-0.71.4
Time in novel zone, NPP test0.70.82.90.30.5-0.10.4-1.3-0.21.11.1-0.61.7
Total zone transitions, NPP test0.10.10.4-0.50.60.0-0.20.3-0.1-0.1-0.1-0.2-0.4
Total locomotion distance, NPP test1.01.32.30.61.41.0-0.90.2-1.31.41.4-1.50.9
Locomotion velocity, NPP test1.41.93.20.91.41.5-1.40.8-1.71.51.5-1.80.7
Intraocular pressure0.71.03.6-0.90.3-1.01.3-1.90.60.10.10.31.6
Delta distance traveled before/after self-admin0.91.01.8-1.1-1.3-0.90.8-0.41.0-1.1-1.11.2-0.4
Delta ambulatory time before/after self-admin0.81.01.4-1.1-1.2-1.01.0-0.81.1-1.0-1.01.0-0.1
Parametrial fat weight6.314.834.0-5.82.7-5.15.0-4.93.8-2.4-2.42.01.4
Pavlov. Cond. lever latency0.40.41.80.4-1.3-0.60.7-0.70.7-0.2-0.20.70.4
Pavlov. Cond. magazine entry latency0.00.10.2-0.50.4-0.10.00.10.1-0.2-0.20.0-0.2
Pavlov. Cond. change in total contacts0.30.41.3-1.10.6-0.50.30.00.4-0.7-0.70.3-0.6
Pavlov. Cond. index score0.20.20.8-0.90.7-0.30.10.10.2-0.4-0.40.1-0.5
Pavlov. Cond. latency score0.10.10.5-0.70.7-0.1-0.00.20.0-0.3-0.3-0.0-0.5
Pavlov. Cond. lever contacts0.20.20.7-0.80.7-0.20.00.20.1-0.4-0.40.1-0.6
Pavlov. Cond. magazine entry number0.20.30.70.8-0.00.5-0.40.0-0.50.70.7-0.50.6
Pavlov. Cond. intertrial magazine entries1.41.76.8-0.12.60.8-0.80.2-1.21.31.3-1.71.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.90.7-0.30.20.00.2-0.4-0.40.1-0.4
Pavlov. Cond. response bias0.10.10.5-0.60.3-0.1-0.10.30.1-0.4-0.40.2-0.7
Pavlov. Cond. lever latency0.50.72.50.50.31.0-1.21.6-0.70.00.0-0.5-1.0
Pavlov. Cond. magazine entry latency1.11.32.1-0.7-1.3-1.31.4-1.21.4-0.9-0.91.4-0.0
Pavlov. Cond. change in total contacts0.40.61.6-0.3-0.8-0.91.1-1.30.8-0.3-0.30.70.6
Pavlov. Cond. index score0.71.02.3-0.7-0.7-1.31.4-1.51.1-0.5-0.50.90.6
Pavlov. Cond. latency score0.60.82.0-0.6-0.7-1.21.3-1.41.0-0.4-0.40.90.5
Pavlov. Cond. lever contacts0.20.31.3-0.50.1-0.70.8-1.10.40.00.00.20.8
Pavlov. Cond. magazine entry number0.70.91.50.80.81.2-1.21.0-1.10.80.8-1.10.1
Pavlov. Cond. intertrial magazine entries0.20.31.8-0.71.3-0.20.1-0.1-0.10.00.0-0.50.1
Pavlov. Cond. lever-magazine prob. diff.0.60.81.8-0.7-0.7-1.21.3-1.31.0-0.6-0.60.90.4
Pavlov. Cond. response bias0.60.82.7-0.5-0.4-1.01.3-1.60.8-0.1-0.10.61.0
Time in closed arm before self-admin0.40.61.5-1.2-0.1-0.40.20.30.5-1.1-1.10.7-0.9
Time in closed arm after self-admin0.70.82.5-0.5-0.30.8-0.91.4-0.4-0.8-0.80.3-1.6
Time in open arm before self-admin1.71.85.32.30.01.3-1.20.5-1.31.71.7-1.40.5
Time in open arm after self-admin0.80.82.01.0-0.9-0.71.0-1.40.50.60.60.11.4
Bone: periosteal estimation0.71.54.5-1.72.1-1.31.3-1.70.60.00.0-0.31.2
Bone: periosteal perimeter2.03.47.8-2.81.1-2.42.3-2.11.9-1.5-1.51.20.1
Bone: post-yield work1.42.15.30.71.70.5-0.2-1.0-1.11.81.8-1.72.3
Progressive ratio test 1 active lever presses0.70.82.50.1-1.60.0-0.10.80.4-1.0-1.01.0-1.5
Progressive ratio test 1 breakpoint0.60.82.30.1-1.50.1-0.10.80.4-1.0-1.00.9-1.4
Progressive ratio test 1 inactive lever presses0.30.40.7-0.4-0.8-0.60.7-0.60.7-0.6-0.60.7-0.3
Progressive ratio test 2 active lever presses0.81.01.8-0.8-0.9-0.90.70.11.0-1.3-1.31.1-1.1
Progressive ratio test 2 breakpoint0.91.01.7-0.8-0.9-0.90.70.11.1-1.3-1.31.1-1.0
Progressive ratio test 2 inactive lever presses0.10.20.40.6-0.30.10.1-0.6-0.20.50.5-0.30.6
Incentive Sensitization - Responses1.11.52.2-1.4-0.6-1.51.3-0.51.5-1.5-1.51.3-0.6
Incentive Sensitization - Breakpoint1.21.52.3-1.4-0.7-1.51.4-0.61.5-1.4-1.41.3-0.5
Sum of active levers in priming session hrs 5-62.01.92.9-0.8-1.5-1.61.6-1.11.7-1.4-1.41.7-0.0
Progressive ratio0.81.23.51.9-1.11.3-1.00.3-1.11.21.2-0.70.5
Food seeking constrained by brief footshock0.10.10.20.4-0.30.4-0.30.3-0.30.30.3-0.00.1
Seeking ratio, punishment vs. effort0.81.22.9-1.70.7-0.80.50.50.9-1.5-1.50.9-1.2
Retroperitoneal fat weight6.628.072.9-8.56.0-6.66.4-6.84.4-2.4-2.41.52.8
Reaction time number correct1.12.23.6-1.0-1.7-1.51.4-0.61.7-1.7-1.71.9-1.2
Reaction time mean minus median1.22.94.6-1.7-1.2-1.71.5-0.41.9-2.1-2.12.1-1.5
Reaction time mean minus median AUC2.15.39.5-2.0-2.0-1.71.40.42.2-3.1-3.12.8-2.9
Reaction time num false alarms0.50.82.5-0.01.60.9-1.00.7-1.10.60.6-1.00.0
Reaction time num false alarms AUC0.40.61.9-0.21.40.9-1.00.9-0.90.30.3-0.8-0.4
Reaction time trials correct on left1.12.23.6-1.0-1.7-1.51.4-0.61.7-1.7-1.71.9-1.2
Reaction time trials on left1.32.54.1-1.1-1.8-1.61.5-0.71.8-1.8-1.82.0-1.2
Reaction time mean3.04.88.0-1.4-2.5-1.61.30.32.2-2.8-2.82.8-2.5
Reaction time mean AUC3.55.69.4-1.4-2.8-1.71.40.42.3-3.1-3.13.0-2.8
Median of all reaction times3.14.57.6-1.1-2.6-1.31.00.62.0-2.8-2.82.7-2.7
Reaction time omissions3.34.87.2-1.8-1.8-2.52.4-1.42.6-2.4-2.42.7-1.0
Reaction time false alarm rate1.52.15.00.42.21.5-1.50.8-1.71.31.3-1.80.6
Reaction time premature initiation rate0.30.41.8-0.41.30.6-0.70.8-0.60.10.1-0.5-0.4
Reaction time premature initiations0.30.51.1-1.00.3-0.30.20.40.4-0.9-0.90.6-1.1
Std. dev. reaction times2.44.57.0-2.2-1.4-2.21.9-0.62.3-2.6-2.62.6-1.8
Reaction time trials completed1.32.54.1-1.1-1.8-1.61.5-0.71.8-1.8-1.82.0-1.2
Reaction time trials AUC1.22.23.7-1.2-1.6-1.51.4-0.71.7-1.7-1.71.9-1.1
Run reversals in cocaine runway, females0.20.20.3-0.4-0.5-0.50.5-0.50.5-0.4-0.40.60.0
Run reversals in cocaine runway, males0.30.31.0-0.10.50.5-0.61.0-0.3-0.3-0.30.1-1.0
Latency to leave start box in cocaine runway2.12.46.9-0.6-2.6-1.01.0-0.21.5-1.8-1.82.1-1.3
Latency to leave start box in cocaine runway, F1.11.22.3-0.6-1.5-1.01.0-0.51.2-1.3-1.31.5-0.6
Latency to leave start box in cocaine runway, M1.21.12.6-0.6-1.6-0.40.30.40.8-1.3-1.31.3-1.4
Std. dev. time between licks in bursts1.31.83.31.80.01.1-0.7-0.3-1.31.81.8-1.31.7
Total sessions with >9 infusions0.30.40.80.70.00.9-0.90.7-0.80.30.3-0.5-0.5
Short access day 1 total inactive lever presses0.60.81.51.2-0.10.8-0.4-0.7-1.01.21.2-0.81.1
Short access day 10 total inactive lever presses0.20.52.0-1.40.6-0.60.5-0.50.5-0.7-0.70.4-0.2
Short access day 1 total infusions0.10.10.40.10.00.4-0.40.4-0.3-0.4-0.40.2-0.6
Short access day 10 total infusions0.81.02.31.2-0.81.2-1.31.5-0.80.00.0-0.1-1.2
Short access total infusions0.60.71.41.1-0.31.2-1.21.1-0.90.40.4-0.4-0.6
Short access day 1 locomotion0.70.91.9-0.5-1.3-0.30.30.20.6-1.3-1.31.2-1.4
Short access day 10 total locomotion0.50.93.6-0.7-0.50.3-0.41.00.2-1.2-1.20.9-1.9
Short access total locomotion0.91.13.80.5-0.51.1-1.31.8-0.6-0.5-0.50.2-2.0
One hour access (0.3 mA shock)1.01.22.80.1-1.7-1.31.4-1.01.4-0.7-0.71.20.0
Compulsive drug intake0.70.81.7-1.0-0.0-1.11.2-1.30.9-0.6-0.60.70.6
One hour access (shock baseline)0.20.41.61.1-1.30.1-0.10.50.1-0.0-0.00.2-0.5
Social response proportion0.50.62.0-1.21.40.0-0.30.6-0.0-0.6-0.6-0.1-1.0
Social responses0.60.82.7-1.61.5-1.00.9-0.90.6-0.4-0.40.10.2
Social time1.72.34.7-1.3-1.1-1.10.80.51.5-2.0-2.01.7-2.2
Soleus weight3.510.318.1-4.1-0.5-3.12.3-0.23.4-4.3-4.33.3-3.6
Bone: stiffness1.01.55.5-0.22.40.3-0.2-0.7-0.91.31.3-1.51.6
Tibialis anterior weight1.55.27.9-2.4-1.3-2.82.5-1.52.8-2.5-2.52.5-1.3
Time to tail flick, vehicle, before self-admin1.21.22.40.91.00.8-0.6-0.2-1.11.51.5-1.51.2
Time to tail flick, vehicle, after self-admin0.10.21.0-0.11.0-0.20.2-0.40.00.20.2-0.30.6
Time to tail flick, test, before self-admin1.11.23.80.50.11.2-1.41.9-0.8-0.4-0.4-0.1-1.8
Time to tail flick, test, after self-admin0.50.51.50.8-1.0-0.20.4-0.90.10.60.6-0.01.2
Delta time to tail flick, vehicle, before/after SA1.61.62.6-1.2-0.6-1.61.5-1.01.6-1.3-1.31.40.0
Delta time to tail flick, test, before/after SA0.80.83.30.4-0.3-0.40.7-1.30.11.01.0-0.41.8
Tibia length0.10.31.9-0.41.40.2-0.30.0-0.50.40.4-0.70.3
Ambulatory time before self-admin1.11.75.31.00.61.5-1.72.3-1.10.00.0-0.5-1.8
Ambulatory time after self-admin0.60.72.50.2-0.70.4-0.61.30.0-0.8-0.80.5-1.6
Bone: tissue strength0.10.10.20.5-0.50.10.0-0.2-0.00.30.30.00.5
Total heroin consumption2.52.94.9-2.1-0.3-2.22.2-1.71.9-1.7-1.71.70.3
Bone: trabecular number0.81.34.6-0.80.9-1.11.4-2.20.50.50.5-0.21.8
Bone: trabecular spacing0.30.41.81.2-1.40.6-0.50.6-0.30.20.20.2-0.3
Bone: trabecular thickness1.72.14.9-2.21.3-1.91.8-2.01.3-0.7-0.70.50.7
Bone: trabecular tissue density0.71.02.60.5-1.40.4-0.61.50.2-0.9-0.90.8-1.6
Water consumed over 24 hours0.10.10.40.3-0.10.5-0.50.6-0.30.00.0-0.2-0.4
Number of responses in last shaping day0.10.10.20.4-0.20.2-0.30.5-0.1-0.2-0.20.0-0.4