Hub : Traits

Total heroin consumption

(sum of all infusions from LGA sessions 1-12) * 20

Tags: Behavior · Heroin

Project: u01_peter_kalivas

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr5	170075070	170847497	1	1	5.38e-09	2.53e-01	1.00e+00	Arhgef16
2	chr8	41432021	42517271	1	1	6.21e-08	1.33e-03	9.25e-01	Foxred1
3	chr9	83390749	84777604	1	1	4.46e-248	1.39e-01	1.00e+00	Retreg2
4	chr17	61510864	62906219	1	1	7.07e-36	1.44e-01	3.56e-10	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1281.17	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
BMI without tail	72013.97	2	2	50	0	1.00e+00	Ccny Retreg2
Body weight	3.91	1	0	0	0	1.00e+00	Retreg2
Epididymis fat weight	54253.01	2	2	50	0	1.00e+00	Ccny Retreg2
Glucose	2366.35	1	1	25	0	1.00e+00	Retreg2
Heart weight	6763.89	2	2	50	0	1.00e+00	Ccny Retreg2
Left kidney weight	47087.73	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Right kidney weight	38954.96	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Tail length	30711.47	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Length with tail	3070.34	2	1	25	0	1.00e+00	Foxred1 Retreg2
Length without tail	64667	2	2	50	0	1.00e+00	Ccny Retreg2
Liver weight, left	7265.45	2	2	50	0	1.00e+00	Ccny Retreg2
Liver weight, right	129.69	2	1	25	0	1.00e+00	Ccny Retreg2
Parametrial fat weight	157.49	4	1	25	0.93	7.21e-02	Arhgef16 Ccny Foxred1 Retreg2
Retroperitoneal fat weight	8029.31	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Intraocular pressure	40071.91	1	1	25	0	1.00e+00	Retreg2
Extensor digitorum longus weight	2344.57	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Soleus weight	43.14	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Tibialis anterior weight	2448.56	2	2	50	0	1.00e+00	Arhgef16 Retreg2
Tibia length	1633.98	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Number of licking bursts	78561.42	2	1	25	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	35414.72	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Times rat made contact with spout	158.98	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Mean time between licks in bursts	66504.91	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Mean num. licks in bursts	47536.44	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Std. dev. time between licks in bursts	47024.76	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Water consumed over 24 hours	51711.02	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	66593.63	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function ln k	71038.09	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function log k	71038.09	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 0 sec	60133.23	2	1	25	0	1.00e+00	Foxred1 Retreg2
Patch foraging total patch changes 12 sec	3670.27	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Patch foraging total patch changes 18 sec	58887.78	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 24 sec	55704.02	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Patch foraging total patch changes 6 sec	16352.42	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging time to switch 0 sec	156618.53	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	80953.12	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	34430.36	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Patch foraging water rate 24 sec	2357.13	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 6 sec	2028.63	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotor activity	26.33	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Locomotor testing distance	22392.02	4	2	50	-0.88	1.21e-01	Arhgef16 Ccny Foxred1 Retreg2
Locomotor testing rearing	76209.02	2	1	25	0	1.00e+00	Foxred1 Retreg2
Light reinforcement 1	77669.42	2	2	50	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	54020.7	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time number correct	76747.74	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	102906.71	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median AUC	104199.98	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Reaction time num false alarms	28557.11	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time num false alarms AUC	53265.52	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	76747.74	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	75015.72	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean	31463.75	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Reaction time mean AUC	37784.15	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Median of all reaction times	15718.31	2	2	50	0	1.00e+00	Arhgef16 Retreg2
Reaction time omissions	34267.91	1	1	25	0	1.00e+00	Retreg2
Reaction time false alarm rate	891.26	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiation rate	12301.54	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Reaction time premature initiations	46243.53	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Std. dev. reaction times	74744.81	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time trials completed	75015.72	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	75869.15	2	2	50	0	1.00e+00	Ccny Retreg2
Social response proportion	35302.65	1	1	25	0	1.00e+00	Retreg2
Social responses	2856.43	2	2	50	0	1.00e+00	Ccny Retreg2
Social time	14750.11	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Conditioned locomotion	2039.45	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Cocaine response after cond. corrected	21944.59	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Cocaine response after cond. not corrected	21421.93	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Cocaine response before conditioning	1409.02	2	1	25	0	1.00e+00	Ccny Retreg2
Saline control response	12962.78	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	9691.24	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	7938.93	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	16478.18	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Pavlov. Cond. change in total contacts	114781.94	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	16002.06	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Pavlov. Cond. latency score	19496.6	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Pavlov. Cond. lever contacts	11037.36	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	104933.78	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	14962.82	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Pavlov. Cond. response bias	1726.57	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Conditioned reinforcement - actives	63835.96	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Conditioned reinforcement - inactives	51686.28	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Conditioned locomotion	13824.85	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access intake day 1-15 change	70209.02	3	3	75	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access intake escalation	104787.33	2	2	50	0	1.00e+00	Foxred1 Retreg2
Intermittent access intake escalation 2	36059.12	3	3	75	0	1.00e+00	Ccny Foxred1 Retreg2
Intermitt. access day 1 inactive lever presses	118272.07	2	1	25	0	1.00e+00	Ccny Retreg2
Intermitt. access day 15 inactive lever presses	104128.18	2	2	50	0	1.00e+00	Foxred1 Retreg2
Intermitt. access escalation Index	92502.05	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 total infusions	51844.35	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access day 15 total infusions	43843.3	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access terminal intake (last 3 days)	27748.25	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access total infusions	234.73	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access day 1 locomotion	34833.31	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access day 15 total locomotion	88947.95	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	711.59	1	1	25	0	1.00e+00	Retreg2
Intermittent access standard deviation	67320.25	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Cocaine induced anxiety	40077.47	4	2	50	-0.9	9.94e-02	Arhgef16 Ccny Foxred1 Retreg2
Post-drug Anxiety	10234.75	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Baseline Anxiety	34515.07	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Lifetime Intake	2296.41	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Incentive Sensitization - Responses	81797.54	2	2	50	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Breakpoint	47604.1	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Progressive ratio test 1 active lever presses	49966.26	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 breakpoint	48151.76	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 inactive lever presses	50372.64	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Progressive ratio test 2 active lever presses	28633.56	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 breakpoint	17520.06	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 inactive lever presses	54708.99	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Total sessions with >9 infusions	2683.34	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Short access day 1 total inactive lever presses	38138.92	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Short access day 10 total inactive lever presses	108624.06	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 total infusions	27934.97	4	2	50	-0.91	8.75e-02	Arhgef16 Ccny Foxred1 Retreg2
Short access day 10 total infusions	38150.26	2	1	25	0	1.00e+00	Ccny Retreg2
Short access total infusions	17026.24	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	21032.9	4	2	50	0.89	1.12e-01	Arhgef16 Ccny Foxred1 Retreg2
Short access day 10 total locomotion	60541.98	3	3	75	0	1.00e+00	Ccny Foxred1 Retreg2
Short access total locomotion	17076.34	4	2	50	0.9	9.68e-02	Arhgef16 Ccny Foxred1 Retreg2
Compulsive drug intake	21823.26	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
One hour access (0.3 mA shock)	3259.74	3	3	75	0	1.00e+00	Ccny Foxred1 Retreg2
One hour access (shock baseline)	46760.13	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Number of responses in last shaping day	17140.43	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Context. condit. distance diff. score	488.1	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	7310.5	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 1	2213.01	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	9358	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 2	1206.44	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	2332.53	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 7	3744.54	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 8	950.4	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	8496.38	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	2066.34	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	3894.77	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Condit. Reinf. inactive responses	19375.3	1	1	25	0	1.00e+00	Retreg2
Incentive salience index mean	4934.52	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Condit. Reinf. lever presses	7149.29	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	35522.88	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	25	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	24924.95	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	280.53	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	77.91	2	1	25	0	1.00e+00	Ccny Retreg2
Novel to familiar place preference ratio	27759.88	2	1	25	0	1.00e+00	Ccny Retreg2
Novelty place preference	27195.73	2	1	25	0	1.00e+00	Ccny Retreg2
Time in novel zone, NPP test	20425.08	2	1	25	0	1.00e+00	Ccny Retreg2
Total zone transitions, NPP test	4119.86	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Total locomotion distance, NPP test	3566.83	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion velocity, NPP test	2031.76	2	2	50	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	1101.48	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Pavlov. Cond. magazine entry latency	8.88	2	0	0	0	1.00e+00	Arhgef16 Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	889.17	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Pavlov. Cond. latency score	924.69	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Pavlov. Cond. lever contacts	1519.32	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Pavlov. Cond. magazine entry number	726.77	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Pavlov. Cond. intertrial magazine entries	265.87	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	973.83	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Pavlov. Cond. response bias	1309.22	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: apparent density	22268.03	1	1	25	0	1.00e+00	Retreg2
Bone surface	25125.6	1	1	25	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	25	0	1.00e+00	Retreg2
Bone: connectivity density	7098.55	1	1	25	0	1.00e+00	Retreg2
Bone: cortical apparent density	22635.68	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: cortical area	18930.98	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	923.42	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: cortical porosity	4807.78	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	816.94	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: cortical thickness	6098.48	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: cortical tissue density	24229.43	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: elastic displacement	14815.6	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: elastic work	1494.59	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal estimation	35257.61	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal perimeter	22351.12	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: final force	7031.22	1	1	25	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	25	0	1.00e+00	Retreg2
Bone: marrow area	37067.95	1	1	25	0	1.00e+00	Retreg2
Bone: maximum diameter	24401.62	1	1	25	0	1.00e+00	Retreg2
Bone: maximum force	34553.99	1	1	25	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	25	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal perimeter	43183.28	1	1	25	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	25	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	25	0	1.00e+00	Retreg2
Bone: tissue strength	6137.24	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: trabecular number	20571.52	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Bone: trabecular spacing	31287.85	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular thickness	33264.33	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular tissue density	17881.44	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Breakpoint value in progressive ratio session	56221.29	2	1	25	0	1.00e+00	Ccny Retreg2
Distance traveled before self-admin	44695.61	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Distance traveled after self-admin	33650.45	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Delta time in closed arm before/after self-admin	524.76	4	2	50	0.99	8.42e-03	Arhgef16 Ccny Foxred1 Retreg2
Delta time in open arm before/after self-admin	27441.91	2	2	50	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	108490.77	1	1	25	0	1.00e+00	Retreg2
Extinction: sum of active levers before priming	22954.71	4	4	100	0.91	8.80e-02	Arhgef16 Ccny Foxred1 Retreg2
Active lever presses in extinction session 6	1120.26	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Delta distance traveled before/after self-admin	4197.63	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Delta ambulatory time before/after self-admin	32038.95	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Time in closed arm before self-admin	29430.48	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Time in closed arm after self-admin	9901.19	2	2	50	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	17365.6	2	2	50	0	1.00e+00	Ccny Retreg2
Time in open arm after self-admin	657.22	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Sum of active levers in priming session hrs 5-6	3877.89	1	1	25	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	17290.32	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Time to tail flick, vehicle, after self-admin	39441.03	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Time to tail flick, test, before self-admin	8219.48	4	2	50	-0.88	1.22e-01	Arhgef16 Ccny Foxred1 Retreg2
Time to tail flick, test, after self-admin	1504.87	4	2	50	0.95	4.90e-02	Arhgef16 Ccny Foxred1 Retreg2
Delta time to tail flick, vehicle, before/after SA	18449.53	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time to tail flick, test, before/after SA	28423.85	2	1	25	0	1.00e+00	Ccny Retreg2
Ambulatory time before self-admin	57052.95	3	3	75	0	1.00e+00	Ccny Foxred1 Retreg2
Ambulatory time after self-admin	44153.3	2	2	50	0	1.00e+00	Ccny Retreg2
Area under the delay curve	27218.3	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Delay disc. indifference point, 0s delay	3163.92	3	1	25	0	1.00e+00	Arhgef16 Ccny Retreg2
Delay disc. indifference point, 16s delay	24963.81	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Delay disc. indifference point, 2s delay	286.06	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	50	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	1298.29	2	2	50	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 8s delay	50743.74	2	2	50	0	1.00e+00	Arhgef16 Retreg2
Delay discount exponential model param	20089.53	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Delay discount hyperbolic model param	22878.48	2	2	50	0	1.00e+00	Arhgef16 Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	25	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	11821.21	2	2	50	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	24655.43	2	2	50	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 1	20842.46	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	5936.78	2	2	50	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	37983.55	2	1	25	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 1	79651.82	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 1	219061.96	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	80995.71	2	1	25	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	58110.85	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Total resting periods, locomotor time 2	63368.4	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Rest time, locomotor task time 2	41900.71	2	2	50	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	69238.05	2	2	50	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	81026.62	2	2	50	0	1.00e+00	Ccny Retreg2
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	8161.06	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber post-restriction	77324.49	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio	78975.01	2	2	50	0	1.00e+00	Ccny Retreg2
Food seeking constrained by brief footshock	7338.76	1	1	25	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	59148.59	2	2	50	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, females	12403.43	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Run reversals in cocaine runway, males	9965.89	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Latency to leave start box in cocaine runway	19547.12	3	2	50	0	1.00e+00	Arhgef16 Ccny Retreg2
Latency to leave start box in cocaine runway, F	14200.04	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Latency to leave start box in cocaine runway, M	2453.48	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Co content in liver	4721.74	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	92.59	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Fe content in liver	2832.41	2	1	25	0	1.00e+00	Arhgef16 Retreg2
K content in liver	3343.42	2	2	50	0	1.00e+00	Arhgef16 Retreg2
Mg content in liver	12257.29	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Mn content in liver	2192.23	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Na content in liver	8336.38	2	2	50	0	1.00e+00	Arhgef16 Retreg2
Rb content in liver	219.6	2	1	25	0	1.00e+00	Arhgef16 Retreg2
Se content in liver	7.68	1	0	0	0	1.00e+00	Arhgef16
Sr content in liver	37.52	1	1	25	0	1.00e+00	Arhgef16
Zn content in liver	7881.92	2	1	25	0	1.00e+00	Arhgef16 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.13
Adipose	alternative TSS	0	0	1.12
Adipose	gene expression	0	0	1.18
Adipose	isoform ratio	0	0	1.11
Adipose	intron excision ratio	0	0	1.07
Adipose	mRNA stability	0	0	1.18
BLA	alternative polyA	0	0	1.19
BLA	alternative TSS	0	0	1.15
BLA	gene expression	0	0	1.17
BLA	isoform ratio	0	0	1.17
BLA	intron excision ratio	0	0	1.1
BLA	mRNA stability	0	0	1.21
Brain	alternative polyA	0	0	1.17
Brain	alternative TSS	0	0	1.18
Brain	gene expression	0	0	1.2
Brain	isoform ratio	0	0	1.18
Brain	intron excision ratio	0	0	1.15
Brain	mRNA stability	0	0	1.2
Eye	alternative polyA	0	0	1.09
Eye	alternative TSS	0	0	1.01
Eye	gene expression	0	0	1.19
Eye	isoform ratio	0	0	1.11
Eye	intron excision ratio	0	0	1.12
Eye	mRNA stability	0	0	1.14
IC	alternative polyA	0	0	1.26
IC	alternative TSS	0	0	1.19
IC	gene expression	0	0	1.2
IC	isoform ratio	0	0	1.22
IC	intron excision ratio	0	0	1.14
IC	mRNA stability	0	0	1.2
IL	alternative polyA	0	0	1.23
IL	alternative TSS	0	0	1.17
IL	gene expression	0	0	1.16
IL	isoform ratio	0	0	1.21
IL	intron excision ratio	0	0	1.08
IL	mRNA stability	0	0	1.14
LHb	alternative polyA	0	0	1.36
LHb	alternative TSS	0	0	1.15
LHb	gene expression	0	0	1.18
LHb	isoform ratio	0	0	1.21
LHb	intron excision ratio	0	0	1.03
LHb	mRNA stability	0	0	1.25
Liver	alternative polyA	0	0	1.19
Liver	alternative TSS	0	0	1.18
Liver	gene expression	1	0	1.18
Liver	isoform ratio	0	0	1.19
Liver	intron excision ratio	0	0	1.1
Liver	mRNA stability	0	0	1.18
NAcc	alternative polyA	1	0	1.55
NAcc	alternative TSS	0	0	1.18
NAcc	gene expression	0	0	1.2
NAcc	isoform ratio	0	0	1.19
NAcc	intron excision ratio	1	0	1.16
NAcc	mRNA stability	0	0	1.23
OFC	alternative polyA	0	0	1.3
OFC	alternative TSS	0	0	1.09
OFC	gene expression	0	0	1.17
OFC	isoform ratio	0	0	1.19
OFC	intron excision ratio	0	0	1.09
OFC	mRNA stability	0	0	1.16
PL	alternative polyA	0	0	1.24
PL	alternative TSS	0	0	1.16
PL	gene expression	0	0	1.19
PL	isoform ratio	0	0	1.17
PL	intron excision ratio	0	0	1.17
PL	mRNA stability	0	0	1.17
pVTA	alternative polyA	0	0	1.25
pVTA	alternative TSS	0	0	1.16
pVTA	gene expression	1	0	1.19
pVTA	isoform ratio	0	0	1.24
pVTA	intron excision ratio	0	0	1.15
pVTA	mRNA stability	0	0	1.23
RMTg	alternative polyA	0	0	1.13
RMTg	alternative TSS	0	0	1.11
RMTg	gene expression	0	0	1.18
RMTg	isoform ratio	0	0	1.23
RMTg	intron excision ratio	0	0	1
RMTg	mRNA stability	0	0	1.24