Hub : Genes

Ormdl3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ormdl3 0.07 0.04 1.1e-09 0.08 0.08 0.08 0.08 6.8e-09 2.9e-09 6.9e-09 6.0e-09
2 NAcc intron excision ratio chr10_84089154_84092182 0.01 0.01 6.8e-03 0.01 0.01 0.01 0 2.3e-02 1.2e-02 2.7e-02 4.8e-02
3 Adipose isoform ratio NM_001413294.1 0.2 0.18 1.8e-06 0.06 0.03 0.06 0.04 8.6e-07 1.1e-04 7.4e-07 9.8e-06
4 Brain gene expression Ormdl3 0.04 0.03 1.1e-03 0.02 0.03 0.03 0.02 2.3e-03 1.6e-03 8.2e-04 2.3e-03
5 Adipose isoform ratio NM_001413293.1 0.15 0.17 3.8e-06 0.05 0.03 0.06 0.04 1.4e-06 1.7e-04 8.2e-07 9.1e-06
6 NAcc intron excision ratio chr10_84089149_84092182 0.02 0.01 6.6e-03 0.01 0.01 0 0 2.1e-02 8.4e-03 1.3e-01 7.4e-02
7 NAcc gene expression Ormdl3 0.07 0.05 7.1e-05 0.03 0.02 0.02 0.03 2.5e-05 4.6e-04 7.1e-04 7.9e-05
8 Adipose alternative TSS NM_001413294.1 0.11 0.08 7.9e-09 0.08 0.07 0.07 0.04 6.5e-09 2.7e-08 2.9e-08 6.9e-05
9 Adipose alternative TSS XM_063269423.1 0.11 0.07 1.9e-08 0.07 0.07 0.07 0.03 1.5e-08 5.7e-08 4.5e-08 1.2e-04
10 Brain mRNA stability Ormdl3 0.05 0.03 4.6e-04 0.04 0.04 0.03 0.04 1.2e-04 8.7e-05 4.1e-04 1.3e-04
11 Liver gene expression Ormdl3 0.06 0.04 7.7e-04 0.01 0.01 0.02 0.02 1.5e-02 4.1e-02 9.9e-04 2.3e-03
12 Adipose gene expression Ormdl3 0.35 0.11 0.0e+00 0.21 0.19 0.27 0.23 5.5e-23 3.1e-20 6.1e-30 2.9e-25
13 Liver mRNA stability Ormdl3 0.03 0.03 8.9e-05 0.03 0.03 0.04 0.02 4.2e-04 5.1e-04 9.1e-06 1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.52.74.21.92.0-1.9-1.41.9-2.1-2.0-1.61.6-1.5-0.6-0.41.5
Area under the delay curve0.30.51.40.80.8-0.6-1.20.6-0.8-1.2-0.40.4-0.6-0.7-0.50.0
BMI with tail2.89.812.9-3.4-2.93.13.6-3.12.72.53.5-3.53.53.53.3-0.9
BMI without tail0.94.67.1-2.4-2.11.82.7-1.72.02.12.4-2.42.32.42.4-0.3
Body weight7.030.841.0-6.2-5.75.76.4-5.65.55.95.8-5.85.85.54.9-2.0
Weight adjusted by age0.30.92.8-0.6-0.21.31.3-1.20.10.30.7-0.70.81.71.3-0.2
Bone surface0.20.31.2-0.10.1-0.00.50.1-0.2-0.10.2-0.20.41.01.11.1
Bone volume0.30.62.90.20.5-0.10.50.2-0.6-0.50.3-0.30.41.21.41.7
Breakpoint value in progressive ratio session0.30.52.5-0.4-0.50.71.1-0.70.51.60.4-0.4-0.20.70.20.4
Number of licking bursts0.10.41.10.20.50.10.4-0.1-0.7-0.70.5-0.50.31.01.10.9
Context. condit. distance diff. score0.80.92.8-0.9-1.30.9-0.2-1.01.40.90.6-0.60.6-0.7-0.9-1.7
Locomotion velocity, session 10.70.81.8-0.9-0.81.01.3-0.90.70.80.9-0.91.01.01.00.2
Locomotion distance, session 12.93.85.8-2.1-1.91.92.4-1.81.82.12.0-2.01.92.12.0-0.3
Locomotion velocity, session 20.10.20.7-0.5-0.50.20.6-0.20.60.8-0.10.10.20.0-0.0-0.3
Locomotion distance, session 20.60.92.3-0.8-0.50.61.4-0.50.41.10.8-0.80.71.51.50.5
Locomotion velocity, session 30.20.20.50.1-0.1-0.4-0.30.40.20.3-0.30.3-0.6-0.7-0.7-0.7
Locomotion distance, session 30.30.40.6-0.6-0.60.60.5-0.60.60.60.7-0.70.40.50.4-0.8
Stereotopy head waving bouts, day 32.73.34.52.01.8-2.0-2.12.0-1.7-2.1-1.91.9-1.7-1.7-1.50.7
Stereotopy head waving duration, day 30.20.30.60.50.5-0.7-0.60.7-0.5-0.8-0.50.5-0.3-0.5-0.30.5
Locomotion velocity, session 71.51.62.4-1.3-1.01.41.5-1.40.90.91.4-1.41.41.61.3-0.2
Locomotion distance, session 70.40.51.0-0.7-0.61.00.7-1.00.60.60.7-0.70.80.80.6-0.2
Stereotopy head waving bouts, day 70.60.62.20.91.0-0.8-1.00.8-1.0-1.5-0.60.6-0.5-0.2-0.20.3
Stereotopy head waving duration, day 70.20.20.80.50.6-0.6-0.60.6-0.6-0.9-0.40.4-0.3-0.2-0.20.0
Locomotion velocity, session 85.97.111.0-3.1-3.22.92.6-2.93.23.32.6-2.62.71.51.2-2.0
Locomotion distance, session 81.31.93.2-1.6-1.61.41.4-1.41.51.81.4-1.41.41.00.9-0.6
Degree of sensitization distance0.50.50.9-0.8-0.90.90.7-0.90.90.70.5-0.50.90.40.3-0.2
Degree of sensitization stereotypy0.60.62.60.91.1-0.7-1.00.7-1.1-1.6-0.40.4-0.30.00.00.4
Conditioned locomotion0.40.40.80.60.5-0.6-0.70.6-0.4-0.3-0.90.9-0.7-0.9-0.8-0.3
Cocaine response after cond. corrected0.50.72.90.71.1-0.3-0.60.4-1.2-1.70.2-0.20.20.91.00.6
Cocaine response after cond. not corrected0.60.93.80.81.2-0.1-0.70.2-1.4-1.90.4-0.40.31.11.20.8
Cocaine response before conditioning0.10.10.30.30.30.0-0.5-0.1-0.3-0.5-0.10.1-0.2-0.2-0.3-0.0
Saline control response0.70.91.8-0.8-0.71.10.6-1.10.60.01.3-1.31.31.31.1-0.1
Bone: connectivity density2.64.15.82.32.4-2.4-1.92.4-2.3-2.3-2.12.1-2.0-1.2-0.91.3
Bone: cortical apparent density5.58.711.83.32.8-2.9-3.42.8-2.7-2.8-3.23.2-3.3-3.2-3.10.7
Bone: cortical area0.10.10.30.40.4-0.1-0.40.1-0.4-0.5-0.10.1-0.20.1-0.00.6
Bone: cortical porosity0.30.41.20.50.7-0.2-0.00.3-0.9-1.0-0.00.00.10.60.81.1
Bone: cortical porosity0.40.41.30.10.40.20.3-0.1-0.6-0.90.3-0.30.71.01.11.0
Bone: cortical thickness1.01.73.01.51.4-1.1-1.71.0-1.3-1.7-1.21.2-1.4-1.2-1.30.3
Bone: cortical thickness4.45.37.02.72.5-2.4-2.42.4-2.4-2.2-2.52.5-2.5-2.1-1.81.3
Bone: cortical tissue density5.58.711.63.32.8-2.9-3.42.9-2.7-2.8-3.33.3-3.3-3.1-3.00.7
Condit. Reinf. active minus inactive responses1.31.52.51.31.1-1.2-1.41.2-1.0-0.7-1.41.4-1.6-1.4-1.4-0.0
Condit. Reinf. active-inactive response ratio2.12.34.11.51.1-1.4-1.91.3-1.0-1.0-1.71.7-1.9-1.9-2.0-0.6
Condit. Reinf. active responses1.01.32.11.31.1-1.1-1.31.1-1.1-0.9-1.31.3-1.4-1.2-1.20.2
Condit. Reinf. inactive responses0.10.10.40.30.5-0.10.10.1-0.6-0.60.1-0.10.10.40.50.6
Incentive salience index mean1.92.53.41.81.6-1.7-1.51.7-1.6-1.3-1.81.8-1.8-1.4-1.30.9
Condit. Reinf. lever presses1.01.52.41.51.5-1.3-0.91.4-1.5-1.3-1.31.3-1.2-0.6-0.51.6
Condit. Reinf. active minus inactive responses0.50.82.21.11.2-0.8-0.30.8-1.2-0.7-0.70.7-1.0-0.1-0.01.5
Condit. Reinf. active-inactive response ratio0.40.73.00.91.1-0.8-0.10.9-1.1-0.6-0.50.5-0.80.10.31.7
Condit. Reinf. active responses0.91.23.91.31.5-1.0-0.21.1-1.6-1.0-0.80.8-1.10.00.22.0
Condit. Reinf. inactive responses0.81.12.31.31.5-1.0-0.61.1-1.5-1.4-0.80.8-0.9-0.10.11.3
Condit. Reinf. lever presses0.00.10.20.30.3-0.2-0.40.2-0.3-0.2-0.10.1-0.5-0.3-0.3-0.1
Condit. Reinf. lever reinforcers received1.01.43.21.41.6-1.2-0.51.2-1.6-1.0-1.01.0-1.4-0.3-0.11.8
Conditioned reinforcement - actives0.00.20.70.40.40.2-0.9-0.2-0.4-0.8-0.30.3-0.2-0.2-0.4-0.2
Conditioned reinforcement - inactives0.10.40.90.50.3-0.7-0.50.7-0.3-0.1-0.80.8-0.7-0.9-0.80.5
Conditioned locomotion0.40.62.00.91.1-0.4-0.80.5-1.1-1.4-0.80.8-0.5-0.1-0.1-0.0
Patch foraging indifference point 0 sec1.23.57.01.91.7-2.0-2.72.0-1.5-1.4-1.91.9-2.0-2.0-1.90.2
Patch foraging indifference point AUC0.00.00.1-0.1-0.00.1-0.1-0.10.00.10.3-0.30.30.30.2-0.4
Delay disc. indifference point, 0s delay1.41.62.41.51.5-1.3-1.41.3-1.5-1.6-1.11.1-1.3-0.9-0.70.7
Delay disc. indifference point, 16s delay0.81.23.00.90.5-0.9-1.70.8-0.4-0.9-1.11.1-0.9-1.7-1.6-0.5
Delay disc. indifference point, 2s delay0.80.93.31.11.3-0.4-0.90.5-1.4-1.8-0.30.3-0.40.20.51.2
Delay disc. indifference point, 24s delay0.10.20.9-0.1-0.2-0.1-0.60.10.2-0.2-0.00.00.1-0.7-0.4-0.9
Delay disc. indifference point, 4s delay0.70.71.61.11.2-0.7-0.90.7-1.2-1.3-0.40.4-0.9-0.4-0.20.7
Delay disc. indifference point, 8s delay0.10.20.70.40.4-0.5-0.80.5-0.4-0.8-0.10.1-0.2-0.5-0.2-0.2
Indifference point function ln k0.10.41.20.1-0.1-0.3-0.90.20.2-0.2-0.50.5-0.4-1.1-1.0-1.0
Indifference point function log k0.10.41.20.1-0.1-0.3-0.90.20.2-0.2-0.50.5-0.4-1.1-1.0-1.0
Patch foraging total patch changes 0 sec0.82.45.51.61.3-1.7-2.31.6-1.2-1.0-1.61.6-1.7-1.8-1.60.0
Patch foraging total patch changes 12 sec3.24.36.92.52.6-2.3-2.02.3-2.6-2.3-1.91.9-2.1-1.0-0.71.8
Patch foraging total patch changes 18 sec0.20.41.00.60.6-0.7-1.00.7-0.6-0.3-0.60.6-0.6-0.5-0.6-0.1
Patch foraging total patch changes 24 sec0.31.12.81.21.3-0.7-1.30.7-1.3-1.7-0.90.9-0.9-0.6-0.7-0.4
Patch foraging total patch changes 6 sec1.42.43.61.71.5-1.8-1.91.8-1.5-1.3-1.61.6-1.6-1.4-1.11.0
Patch foraging time to switch 0 sec0.00.10.30.20.3-0.10.20.1-0.3-0.2-0.40.4-0.20.20.10.6
Patch foraging water rate 0 sec0.10.20.50.40.3-0.6-0.50.6-0.20.1-0.20.2-0.6-0.7-0.40.0
Patch foraging water rate 12 sec0.00.10.6-0.2-0.30.50.4-0.50.30.80.1-0.1-0.2-0.1-0.4-0.3
Patch foraging water rate 18 sec0.20.40.80.70.9-0.7-0.30.7-0.9-0.7-0.40.4-0.6-0.10.10.7
Patch foraging water rate 24 sec0.60.81.50.90.8-1.2-0.51.2-0.7-0.4-0.90.9-1.0-0.8-0.51.2
Patch foraging water rate 6 sec1.21.72.91.51.5-1.6-1.11.6-1.5-1.0-1.21.2-1.7-1.0-0.71.0
Seeking ratio, delayed vs. immediate footshock0.30.52.10.4-0.10.2-0.7-0.30.20.5-0.40.4-0.9-1.3-1.5-0.6
Distance traveled before self-admin0.20.32.50.00.10.10.90.0-0.20.50.0-0.0-0.10.50.71.6
Distance traveled after self-admin0.40.61.4-0.9-0.90.41.2-0.40.91.00.8-0.80.70.50.80.8
Extensor digitorum longus weight7.429.540.6-6.2-6.46.25.2-6.36.35.65.5-5.55.53.52.4-4.4
Bone: elastic displacement0.00.00.20.10.00.0-0.4-0.1-0.0-0.10.0-0.00.0-0.1-0.1-0.5
Bone: elastic work0.10.10.60.20.2-0.0-0.00.0-0.3-0.20.1-0.1-0.00.40.50.8
Bone: endosteal estimation2.25.37.6-2.6-2.22.22.7-2.12.12.32.3-2.32.82.72.6-0.0
Bone: endosteal perimeter1.33.14.5-2.0-1.91.62.1-1.61.82.11.7-1.71.81.71.80.4
Epididymis fat weight0.21.12.4-0.9-0.71.11.4-1.10.50.50.9-0.91.11.51.60.6
Delta time in closed arm before/after self-admin4.34.05.4-2.2-2.22.12.3-2.12.12.12.1-2.12.11.71.3-1.2
Delta time in open arm before/after self-admin0.00.00.10.0-0.0-0.0-0.10.00.00.10.2-0.2-0.0-0.3-0.20.3
Diff in mean of infusions in LGA sessions0.10.20.6-0.1-0.10.30.8-0.30.10.70.2-0.2-0.20.60.30.4
Delay discount exponential model param0.20.31.1-0.6-0.60.51.0-0.40.51.00.2-0.20.40.70.40.1
Extinction: sum of active levers before priming1.11.62.6-1.4-1.31.41.0-1.41.20.81.4-1.41.61.31.0-1.0
Active lever presses in extinction session 60.90.94.00.00.5-0.11.00.3-0.7-0.10.2-0.20.41.72.01.8
Bone: final force0.40.72.00.71.0-0.4-0.30.5-1.1-1.4-0.20.20.10.80.91.4
Bone: final moment0.30.61.90.50.8-0.3-0.10.4-0.9-1.2-0.00.00.30.91.01.4
Food consumed during 24 hour testing period0.40.91.2-1.1-1.10.91.1-1.01.00.61.1-1.11.00.80.80.1
Glucose0.30.51.3-0.00.20.6-0.0-0.6-0.3-0.71.0-1.00.91.11.20.3
Heart weight2.94.76.9-2.4-2.42.62.1-2.62.42.42.2-2.22.21.91.4-0.6
Delay discount hyperbolic model param0.20.30.9-0.6-0.50.40.9-0.30.50.90.1-0.10.40.50.3-0.0
Intermittent access intake day 1-15 change0.00.10.50.10.0-0.40.40.40.00.70.1-0.1-0.6-0.1-0.20.3
Intermittent access intake escalation0.00.10.50.1-0.0-0.40.30.30.10.70.1-0.1-0.6-0.2-0.20.4
Intermittent access intake escalation 20.20.31.0-0.6-0.60.00.9-0.10.61.00.7-0.70.20.30.40.1
Intermitt. access day 1 inactive lever presses0.11.83.21.41.3-1.7-0.71.6-1.2-0.4-1.41.4-1.8-1.3-0.91.6
Intermitt. access day 15 inactive lever presses0.52.54.21.61.4-2.1-1.71.9-1.3-1.0-1.51.5-2.0-1.8-1.70.3
Intermitt. access escalation Index0.72.13.1-1.6-1.51.51.2-1.51.40.91.8-1.81.71.21.0-1.3
Intermittent access day 1 total infusions0.00.10.50.20.0-0.0-0.20.0-0.0-0.1-0.50.5-0.1-0.4-0.20.7
Intermittent access day 15 total infusions0.00.10.30.1-0.2-0.2-0.00.10.30.5-0.10.1-0.5-0.6-0.50.5
Intermittent access terminal intake (last 3 days)0.20.30.80.40.2-0.8-0.40.7-0.10.1-0.50.5-0.7-0.9-0.60.6
Intermittent access total infusions0.10.20.50.1-0.1-0.3-0.20.20.20.4-0.40.4-0.4-0.7-0.60.6
Intermittent access day 1 locomotion0.10.20.50.30.2-0.0-0.50.1-0.2-0.5-0.70.7-0.1-0.4-0.30.2
Intermittent access day 15 total locomotion0.10.30.80.60.7-0.3-0.30.4-0.7-0.9-0.70.7-0.30.00.20.7
Intermittent access total locomotion0.91.01.61.11.0-0.9-1.20.9-1.0-1.2-1.31.3-0.9-0.9-0.70.6
Intermittent access standard deviation0.42.04.01.31.1-1.9-0.81.8-1.00.0-1.51.5-2.0-1.5-1.21.4
Left kidney weight0.21.75.0-1.6-1.70.81.9-0.81.72.20.9-0.91.00.70.5-0.7
Right kidney weight0.10.51.8-0.5-0.2-0.11.30.20.20.80.4-0.40.41.01.10.9
Cocaine induced anxiety1.43.85.2-2.3-2.11.82.2-1.82.12.22.2-2.21.81.81.5-1.2
Post-drug Anxiety0.70.81.4-1.1-1.00.70.7-0.71.11.11.1-1.10.70.50.3-1.2
Baseline Anxiety1.22.04.41.71.7-1.1-2.11.1-1.7-2.1-1.31.3-1.2-1.1-1.00.4
Tail length0.31.75.4-1.5-1.61.21.3-1.21.72.30.8-0.80.70.60.2-1.2
Length with tail2.410.822.0-3.7-3.63.44.0-3.33.64.73.0-3.02.72.72.2-1.5
Length without tail1.99.912.9-3.5-3.23.53.6-3.53.13.43.2-3.23.23.12.6-1.2
Times rat made contact with spout0.60.72.00.91.0-0.9-0.50.9-1.1-1.4-0.50.5-0.5-0.10.21.3
Lifetime Intake0.20.30.80.40.1-0.4-0.40.4-0.00.3-0.60.6-0.7-0.9-0.80.7
Liver weight, left0.40.71.5-0.8-0.60.91.0-0.90.50.30.8-0.81.01.21.1-0.1
Liver weight, right0.50.81.40.70.6-1.2-1.11.2-0.6-1.0-1.11.1-0.6-1.0-0.7-0.2
Locomotor activity0.30.51.40.61.0-0.4-0.10.5-1.1-1.2-0.20.2-0.20.60.81.2
Locomotor testing distance1.12.75.01.82.0-1.8-1.71.8-2.0-2.2-1.51.5-1.4-0.9-0.51.1
Locomotor testing rearing2.710.014.03.33.1-3.7-3.63.7-2.9-2.8-3.53.5-3.3-3.1-2.41.2
Locomotion in novel chamber3.54.77.42.72.7-1.8-2.11.9-2.7-2.6-2.32.3-2.0-1.0-0.82.2
Locomotion in novel chamber post-restriction0.20.52.70.40.7-0.40.20.5-0.8-0.40.2-0.2-0.10.81.21.6
Fecal boli incidents, locomotor time 10.10.30.6-0.5-0.50.70.6-0.70.40.40.3-0.30.70.60.6-0.2
Change in fecal boli incidents, locomotor task0.10.10.40.30.30.1-0.6-0.1-0.3-0.70.1-0.1-0.10.0-0.10.2
Time >=10cm from walls, locomotor time 10.50.62.00.70.5-0.0-1.4-0.0-0.4-0.9-0.80.8-0.6-0.8-1.2-1.1
Bouts of movement, locomotor time 10.40.50.9-0.9-0.70.40.9-0.40.70.90.5-0.50.70.50.7-0.6
Total resting periods, locomotor time 10.91.01.7-1.3-1.00.91.3-0.80.91.10.9-0.91.21.01.1-0.5
Rest time, locomotor task time 10.10.20.9-0.2-0.0-0.20.40.3-0.00.1-0.50.50.20.20.51.0
Distance moved, locomotor task time 10.00.10.30.20.10.5-0.4-0.6-0.1-0.30.5-0.50.00.1-0.2-0.5
Vertical activity count, locomotor time 10.11.02.5-0.4-0.51.60.3-1.60.40.21.5-1.50.61.00.4-0.8
Time >=10cm from walls, locomotor time 20.30.82.81.21.20.1-1.20.0-1.3-1.7-0.70.7-0.60.0-0.40.1
Bouts of movement, locomotor time 20.31.01.80.60.5-1.2-0.71.2-0.5-0.2-1.41.4-1.0-1.3-1.2-0.7
Total resting periods, locomotor time 20.20.81.60.40.3-1.0-0.51.0-0.20.1-1.21.2-0.9-1.2-1.3-0.8
Rest time, locomotor task time 20.50.81.3-1.0-1.01.11.0-1.11.01.10.7-0.70.80.80.6-0.4
Distance moved, locomotor task time 20.30.40.8-0.3-0.30.80.2-0.80.3-0.20.9-0.90.80.80.6-0.3
Vertical activity count, locomotor time 20.40.81.9-0.6-0.61.40.2-1.40.60.21.3-1.30.80.80.4-0.9
Light reinforcement 10.83.75.62.12.1-2.4-1.92.4-2.0-1.5-2.02.0-2.1-1.4-0.91.6
Light reinforcement 20.20.52.10.60.8-0.8-0.10.8-0.9-0.7-0.30.3-0.20.30.91.4
Bone: marrow area2.05.07.1-2.5-2.22.12.6-2.02.02.32.1-2.12.72.52.50.0
Bone: maximum diameter0.10.10.90.00.1-0.00.40.1-0.20.20.0-0.00.10.50.50.9
Bone: maximum force0.20.41.2-0.4-0.20.50.6-0.40.1-0.00.6-0.60.81.11.00.6
Bone: maximum moment0.20.51.3-0.6-0.40.60.6-0.50.30.10.7-0.70.91.11.10.5
Mean time between licks in bursts0.32.02.8-1.7-1.61.31.6-1.31.51.71.4-1.41.51.21.2-0.4
Mean num. licks in bursts0.10.41.00.50.3-0.8-0.70.7-0.2-0.3-0.80.8-0.6-1.0-0.80.2
Cd content in liver1.11.32.2-1.3-1.41.11.1-1.21.41.51.0-1.01.10.80.7-0.5
Co content in liver1.11.32.7-1.3-1.61.10.8-1.11.61.60.7-0.70.80.0-0.3-1.4
Cu content in liver0.30.31.00.2-0.1-0.3-0.50.20.20.9-0.60.6-0.9-0.8-1.0-0.3
Fe content in liver2.02.53.1-1.7-1.51.61.8-1.61.41.41.8-1.81.71.71.6-0.1
K content in liver1.01.01.71.00.9-1.1-1.21.1-0.8-0.4-1.21.2-1.3-1.1-1.10.1
Mg content in liver2.02.24.61.10.8-1.3-1.91.3-0.6-0.5-1.71.7-1.6-2.1-2.1-1.0
Mn content in liver2.12.34.21.41.0-1.4-1.91.4-0.9-0.4-1.81.8-1.9-2.1-2.0-0.4
Na content in liver0.50.62.50.10.60.00.70.0-0.7-0.30.4-0.40.31.21.41.6
Rb content in liver1.82.14.31.51.3-1.6-2.11.6-1.3-1.5-1.41.4-1.4-1.4-1.20.5
Se content in liver6.98.211.33.23.0-3.2-2.93.2-2.8-2.1-3.23.2-3.4-2.6-2.31.5
Sr content in liver0.60.51.7-0.1-0.4-0.0-0.3-0.10.61.1-0.70.7-0.7-1.2-1.3-0.9
Zn content in liver3.13.65.32.11.9-2.3-1.72.3-1.8-1.3-2.22.2-2.2-1.7-1.41.2
Bone: minimum diameter0.61.21.7-1.1-1.11.10.9-1.11.01.01.2-1.21.31.31.20.3
Time in familiar zone, hab. session 10.80.83.60.10.40.10.9-0.0-0.6-0.40.6-0.60.61.31.71.9
Time in novel zone, hab. session 11.61.74.11.00.7-1.0-2.00.9-0.5-0.7-1.21.2-1.4-1.8-2.0-1.4
Total zone transitions, hab. session 11.42.02.9-1.6-1.71.61.5-1.61.71.71.4-1.41.30.90.6-1.0
Total locomotion distance, hab. session 10.00.00.10.0-0.10.1-0.1-0.20.20.00.1-0.1-0.3-0.3-0.4-0.0
Locomotion velocity, hab. session 10.20.30.5-0.6-0.70.70.6-0.70.70.60.5-0.50.20.2-0.0-0.3
Time in familiar zone, hab. session 20.30.31.30.60.7-0.5-0.30.5-0.8-0.5-0.10.1-0.30.30.41.1
Time in novel zone, hab. session 20.30.30.70.50.4-0.5-0.50.5-0.3-0.3-0.70.7-0.7-0.8-0.8-0.6
Total zone transitions, hab. session 21.11.42.0-1.2-1.21.40.9-1.41.10.91.4-1.41.31.10.9-0.8
Total locomotion distance, hab. session 20.50.71.3-0.7-0.60.90.8-0.90.50.31.1-1.10.81.11.00.1
Locomotion velocity, hab. session 20.81.01.8-0.9-0.81.21.0-1.20.70.51.3-1.31.01.21.1-0.1
Novel to familiar place preference ratio0.60.72.6-1.0-1.10.80.6-0.81.11.20.3-0.30.4-0.2-0.5-1.6
Novelty place preference0.50.73.1-0.8-1.00.60.3-0.61.01.00.1-0.10.3-0.5-0.8-1.8
Time in novel zone, NPP test0.30.42.6-0.4-0.50.4-0.1-0.40.60.4-0.10.10.0-0.6-0.9-1.6
Total zone transitions, NPP test1.01.53.0-1.0-0.81.31.3-1.30.70.41.5-1.51.51.71.70.4
Total locomotion distance, NPP test0.30.41.3-0.3-0.20.40.4-0.40.1-0.30.8-0.80.71.11.10.8
Locomotion velocity, NPP test0.50.71.2-0.8-0.70.70.9-0.70.70.40.9-0.91.01.01.10.7
Intraocular pressure1.72.74.2-2.0-2.01.81.5-1.82.01.41.5-1.52.01.21.0-1.0
Delta distance traveled before/after self-admin0.80.91.8-1.1-1.20.90.4-1.01.30.71.0-1.00.90.30.1-1.3
Delta ambulatory time before/after self-admin0.81.42.1-1.4-1.31.00.7-1.11.20.51.4-1.41.50.90.8-1.4
Parametrial fat weight0.30.62.20.71.0-0.80.20.9-1.1-0.5-0.30.3-0.40.50.91.5
Pavlov. Cond. lever latency1.51.95.0-1.5-1.81.40.7-1.51.91.81.0-1.00.8-0.3-0.6-2.2
Pavlov. Cond. magazine entry latency7.49.514.93.63.8-3.3-2.43.4-3.9-3.7-3.03.0-2.7-1.3-0.73.5
Pavlov. Cond. change in total contacts9.09.712.23.53.3-3.5-3.23.4-3.2-3.1-3.43.4-3.2-2.6-2.21.9
Pavlov. Cond. index score6.17.712.93.23.5-2.9-2.23.0-3.6-3.5-2.52.5-2.3-0.8-0.33.4
Pavlov. Cond. latency score4.55.710.12.73.1-2.5-1.82.6-3.2-3.1-2.12.1-1.8-0.50.03.1
Pavlov. Cond. lever contacts2.12.56.21.72.1-1.6-0.71.7-2.2-1.9-1.21.2-1.00.20.52.5
Pavlov. Cond. magazine entry number10.413.219.2-4.2-4.34.03.4-4.04.34.43.6-3.63.32.11.5-3.3
Pavlov. Cond. intertrial magazine entries1.01.24.3-1.2-1.31.20.6-1.21.41.20.7-0.70.80.1-0.2-2.1
Pavlov. Cond. lever-magazine prob. diff.7.49.214.83.53.8-3.3-2.43.3-3.8-3.7-2.82.8-2.6-1.1-0.63.5
Pavlov. Cond. response bias8.110.114.63.73.8-3.5-2.83.5-3.8-3.7-3.23.2-2.9-1.7-1.13.2
Pavlov. Cond. lever latency0.30.41.0-0.7-0.80.60.3-0.60.90.90.2-0.20.50.1-0.2-1.0
Pavlov. Cond. magazine entry latency0.20.30.6-0.3-0.10.70.5-0.70.10.20.8-0.80.40.70.60.2
Pavlov. Cond. change in total contacts0.30.81.21.11.0-0.9-0.90.9-0.9-0.8-0.90.9-1.1-0.9-0.80.6
Pavlov. Cond. index score0.10.10.50.30.5-0.2-0.10.2-0.5-0.50.2-0.2-0.10.30.40.7
Pavlov. Cond. latency score0.10.10.30.30.4-0.0-0.00.0-0.5-0.50.3-0.30.00.30.40.6
Pavlov. Cond. lever contacts0.30.41.30.70.8-0.6-0.30.6-0.9-1.0-0.10.1-0.40.10.41.2
Pavlov. Cond. magazine entry number0.00.10.2-0.3-0.3-0.10.10.10.40.3-0.30.30.0-0.3-0.2-0.3
Pavlov. Cond. intertrial magazine entries0.61.24.1-1.2-1.51.00.5-1.11.61.40.4-0.40.4-0.4-0.8-2.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.20.3-0.00.10.0-0.4-0.30.3-0.3-0.00.30.40.6
Pavlov. Cond. response bias0.60.82.41.01.2-0.8-0.40.8-1.3-1.1-0.30.3-0.70.00.31.5
Time in closed arm before self-admin2.34.06.41.71.4-2.5-2.42.5-1.2-1.5-2.32.3-1.9-2.5-1.90.4
Time in closed arm after self-admin0.50.62.0-0.1-0.5-0.5-0.60.40.70.5-0.70.7-0.5-1.4-1.4-0.9
Time in open arm before self-admin2.02.55.0-1.4-1.32.21.5-2.21.21.31.8-1.81.31.91.1-0.6
Time in open arm after self-admin0.40.51.0-0.5-0.50.90.6-0.90.40.71.0-1.00.50.70.40.1
Bone: periosteal estimation0.51.12.3-1.0-0.80.91.1-0.90.60.81.0-1.01.31.51.50.7
Bone: periosteal perimeter1.12.23.5-1.4-1.21.31.8-1.31.01.21.7-1.71.61.81.91.0
Bone: post-yield work0.71.32.0-1.4-1.41.01.3-1.11.41.21.1-1.11.30.80.7-0.5
Progressive ratio test 1 active lever presses0.10.20.60.30.2-0.3-0.80.4-0.2-0.6-0.40.4-0.1-0.4-0.2-0.0
Progressive ratio test 1 breakpoint0.10.10.60.20.1-0.3-0.70.3-0.1-0.5-0.30.3-0.0-0.4-0.2-0.1
Progressive ratio test 1 inactive lever presses0.20.41.00.50.3-0.8-0.60.7-0.20.1-0.70.7-0.8-1.0-0.80.3
Progressive ratio test 2 active lever presses0.60.91.21.11.0-0.9-0.80.9-1.0-0.7-1.11.1-1.1-0.8-0.61.0
Progressive ratio test 2 breakpoint0.70.91.31.11.1-0.9-0.81.0-1.1-0.7-1.11.1-1.1-0.8-0.61.1
Progressive ratio test 2 inactive lever presses0.10.20.60.40.3-0.4-0.10.4-0.30.1-0.60.6-0.6-0.5-0.40.8
Incentive Sensitization - Responses0.51.52.71.41.4-1.2-0.51.3-1.5-0.8-1.31.3-1.3-0.7-0.41.6
Incentive Sensitization - Breakpoint0.61.32.71.41.4-1.1-0.41.2-1.4-0.7-1.31.3-1.2-0.6-0.31.6
Sum of active levers in priming session hrs 5-60.10.10.20.10.2-0.0-0.00.1-0.3-0.5-0.10.10.20.40.50.3
Progressive ratio0.00.10.30.10.20.30.3-0.2-0.30.10.1-0.1-0.10.50.30.0
Food seeking constrained by brief footshock0.40.41.00.50.7-1.0-0.31.0-0.7-0.6-0.60.6-0.4-0.10.31.0
Seeking ratio, punishment vs. effort0.10.10.40.0-0.0-0.6-0.50.50.0-0.5-0.30.30.1-0.6-0.3-0.0
Retroperitoneal fat weight0.10.20.60.40.4-0.7-0.40.8-0.4-0.2-0.70.7-0.3-0.3-0.10.4
Reaction time number correct0.51.72.6-1.1-1.11.61.6-1.61.00.81.5-1.51.21.41.20.7
Reaction time mean minus median0.10.41.2-0.6-0.60.90.6-0.90.60.10.7-0.70.60.50.2-1.1
Reaction time mean minus median AUC0.00.10.5-0.00.10.3-0.0-0.3-0.1-0.70.4-0.40.30.30.1-0.6
Reaction time num false alarms0.40.74.00.70.9-0.4-0.00.5-1.0-1.1-0.30.3-0.10.60.82.0
Reaction time num false alarms AUC0.20.63.20.50.8-0.20.20.3-0.9-0.9-0.00.0-0.10.70.91.8
Reaction time trials correct on left0.51.72.6-1.1-1.11.61.6-1.61.00.81.5-1.51.21.41.20.7
Reaction time trials on left0.51.62.5-1.1-1.11.51.6-1.61.00.81.5-1.51.21.41.20.7
Reaction time mean0.30.61.40.70.5-0.7-0.60.6-0.4-0.1-0.90.9-1.1-1.1-1.2-0.6
Reaction time mean AUC0.30.61.40.60.5-0.7-0.70.7-0.4-0.0-1.01.0-1.1-1.1-1.2-0.7
Median of all reaction times1.11.73.11.31.1-1.4-1.11.3-1.0-0.4-1.61.6-1.8-1.6-1.5-0.1
Reaction time omissions0.30.40.70.80.8-0.7-0.40.7-0.7-0.6-0.80.8-0.9-0.6-0.40.3
Reaction time false alarm rate0.71.01.81.01.3-1.0-0.61.1-1.3-1.3-0.80.8-0.7-0.10.11.3
Reaction time premature initiation rate0.10.20.50.50.7-0.2-0.20.3-0.7-0.4-0.20.2-0.60.20.10.6
Reaction time premature initiations0.10.40.9-0.4-0.20.80.8-0.80.20.30.8-0.80.30.90.70.7
Std. dev. reaction times0.00.10.50.00.10.20.1-0.2-0.1-0.20.0-0.0-0.10.1-0.1-0.7
Reaction time trials completed0.51.62.5-1.1-1.11.51.6-1.61.00.81.5-1.51.21.41.20.7
Reaction time trials AUC0.41.42.5-1.0-1.01.51.4-1.60.90.71.4-1.41.11.31.00.5
Run reversals in cocaine runway, females1.11.32.5-1.1-1.51.30.3-1.41.61.31.2-1.20.70.0-0.7-1.2
Run reversals in cocaine runway, males0.20.20.60.50.5-0.5-0.40.4-0.5-0.8-0.20.2-0.3-0.2-0.00.5
Latency to leave start box in cocaine runway0.81.12.5-1.1-1.41.21.1-1.21.51.61.0-1.00.80.40.2-0.1
Latency to leave start box in cocaine runway, F1.72.13.2-1.5-1.71.81.7-1.81.61.71.4-1.41.31.00.70.1
Latency to leave start box in cocaine runway, M0.40.40.90.40.1-0.7-0.60.7-0.00.3-0.70.7-0.8-1.0-0.9-0.1
Std. dev. time between licks in bursts0.10.20.5-0.5-0.30.20.7-0.20.30.40.4-0.40.40.60.70.3
Total sessions with >9 infusions0.60.72.10.60.2-0.7-1.20.6-0.00.1-0.80.8-1.0-1.5-1.5-0.1
Short access day 1 total inactive lever presses1.02.02.81.61.4-1.6-1.21.6-1.3-1.0-1.61.6-1.7-1.4-1.11.2
Short access day 10 total inactive lever presses0.00.20.9-0.1-0.2-0.00.6-0.00.20.90.6-0.6-0.5-0.0-0.2-0.2
Short access day 1 total infusions0.51.02.50.80.4-1.0-1.20.9-0.2-0.2-1.11.1-1.0-1.6-1.50.2
Short access day 10 total infusions0.40.61.00.70.6-0.9-0.90.8-0.5-0.5-0.90.9-0.7-0.9-0.61.0
Short access total infusions0.40.51.10.60.4-0.7-0.80.6-0.30.1-0.90.9-0.9-1.0-0.90.8
Short access day 1 locomotion1.01.62.21.31.0-1.4-1.51.3-0.9-0.8-1.51.5-1.3-1.5-1.31.0
Short access day 10 total locomotion0.52.04.11.61.7-1.5-1.51.5-1.7-2.0-1.41.4-1.1-0.8-0.41.0
Short access total locomotion0.30.50.80.70.5-0.7-0.90.7-0.5-0.5-0.90.9-0.7-0.9-0.70.6
One hour access (0.3 mA shock)0.20.30.7-0.4-0.50.8-0.0-0.90.50.30.5-0.50.40.2-0.2-0.8
Compulsive drug intake0.71.14.90.0-0.4-0.0-1.7-0.20.5-0.30.2-0.2-0.3-1.4-1.9-2.2
One hour access (shock baseline)0.00.10.5-0.1-0.10.20.6-0.10.10.5-0.10.1-0.00.30.30.7
Social response proportion0.30.30.9-0.6-0.50.70.0-0.70.50.20.4-0.40.90.50.3-0.9
Social responses0.10.10.8-0.00.1-0.1-0.10.1-0.2-0.10.4-0.40.40.70.90.2
Social time0.71.13.5-0.6-0.10.71.1-0.6-0.00.31.3-1.31.01.91.80.6
Soleus weight0.41.23.9-0.40.20.71.0-0.6-0.4-1.21.0-1.01.51.82.00.4
Bone: stiffness0.10.20.7-0.2-0.10.20.5-0.20.0-0.10.3-0.30.40.60.70.8
Tibialis anterior weight1.65.47.3-2.6-2.42.52.7-2.42.21.82.5-2.52.62.21.9-1.2
Time to tail flick, vehicle, before self-admin0.10.10.40.10.2-0.40.10.4-0.2-0.40.3-0.30.20.20.60.6
Time to tail flick, vehicle, after self-admin0.10.20.8-0.00.30.30.4-0.1-0.4-0.30.4-0.40.30.90.8-0.2
Time to tail flick, test, before self-admin1.01.21.6-1.2-1.01.20.9-1.20.90.71.3-1.31.21.10.9-1.2
Time to tail flick, test, after self-admin0.30.42.00.10.3-0.40.50.5-0.3-0.30.0-0.00.30.61.11.4
Delta time to tail flick, vehicle, before/after SA0.40.41.40.30.70.10.50.0-0.9-0.60.1-0.10.21.11.20.9
Delta time to tail flick, test, before/after SA1.82.24.11.71.6-1.7-1.11.7-1.6-1.4-1.61.6-1.3-0.8-0.42.0
Tibia length2.05.79.0-2.5-2.12.42.6-2.41.91.52.8-2.83.02.72.7-0.2
Ambulatory time before self-admin0.10.21.5-0.1-0.10.00.70.00.10.8-0.00.0-0.20.10.21.2
Ambulatory time after self-admin1.32.03.9-1.7-1.51.02.0-1.01.51.61.5-1.51.41.21.50.6
Bone: tissue strength1.01.01.4-1.2-1.21.10.8-1.21.10.81.1-1.11.10.60.4-1.1
Total heroin consumption1.72.09.01.41.7-1.10.21.2-1.8-1.0-1.11.1-1.00.71.03.0
Bone: trabecular number3.36.110.12.93.1-2.7-2.12.8-3.2-3.0-2.42.4-2.1-0.9-0.42.4
Bone: trabecular spacing2.33.34.7-1.8-1.61.92.1-1.91.41.12.2-2.22.12.12.00.1
Bone: trabecular thickness0.00.10.10.30.3-0.30.10.3-0.3-0.2-0.10.1-0.20.10.10.4
Bone: trabecular tissue density0.71.25.00.2-0.2-0.1-1.30.10.40.2-0.90.9-0.8-1.6-2.0-2.2
Water consumed over 24 hours0.20.40.8-0.5-0.40.50.6-0.50.3-0.00.9-0.90.60.80.70.6
Number of responses in last shaping day0.70.92.50.60.2-1.1-1.10.9-0.00.2-1.01.0-1.1-1.5-1.6-0.0