Hub : Genes

Ormdl3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Ormdl3	0.07	0.04	1.1e-09	0.08	0.08	0.08	0.08	6.8e-09	2.9e-09	6.9e-09	5.2e-09
2	NAcc	intron excision ratio	chr10_84089154_84092182	0.01	0.01	6.8e-03	0.01	0.01	0.01	0	2.3e-02	1.2e-02	2.7e-02	4.6e-02
3	Adipose	isoform ratio	NM_001413294.1	0.2	0.18	1.8e-06	0.06	0.03	0.06	0.04	8.6e-07	1.1e-04	7.4e-07	9.4e-06
4	Brain	gene expression	Ormdl3	0.04	0.03	1.1e-03	0.02	0.03	0.03	0.02	2.3e-03	1.6e-03	8.2e-04	2.2e-03
5	Adipose	isoform ratio	NM_001413293.1	0.15	0.17	3.8e-06	0.05	0.03	0.06	0.04	1.4e-06	1.7e-04	8.2e-07	9.0e-06
6	NAcc	intron excision ratio	chr10_84089149_84092182	0.02	0.01	6.6e-03	0.01	0.01	0	0	2.1e-02	8.4e-03	1.3e-01	7.2e-02
7	NAcc	gene expression	Ormdl3	0.07	0.05	7.1e-05	0.03	0.02	0.02	0.03	2.5e-05	4.6e-04	7.1e-04	7.8e-05
8	Adipose	alternative TSS	NM_001413294.1	0.11	0.08	7.9e-09	0.08	0.07	0.07	0.04	6.5e-09	2.7e-08	2.9e-08	6.9e-05
9	Adipose	alternative TSS	XM_063269423.1	0.11	0.07	1.9e-08	0.07	0.07	0.07	0.03	1.5e-08	5.7e-08	4.7e-08	1.2e-04
10	Brain	mRNA stability	Ormdl3	0.05	0.03	4.6e-04	0.04	0.04	0.03	0.04	1.2e-04	8.7e-05	4.8e-04	1.4e-04
11	Liver	gene expression	Ormdl3	0.06	0.04	7.7e-04	0.01	0.01	0.02	0.02	1.5e-02	4.1e-02	9.9e-04	2.4e-03
12	Adipose	gene expression	Ormdl3	0.35	0.11	0.0e+00	0.21	0.19	0.27	0.23	5.5e-23	3.1e-20	6.3e-30	3.3e-25
13	Liver	mRNA stability	Ormdl3	0.03	0.03	8.9e-05	0.03	0.03	0.04	0.02	4.2e-04	5.1e-04	9.1e-06	1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Bone: apparent density	1.6	2.7	4.2	1.9	2.0	1.9	1.4	-1.9	-2.1	2.0	1.6	-1.6	-1.5	0.6	0.4	-1.5
Area under the delay curve	0.4	0.5	1.4	0.8	0.8	0.6	1.2	-0.6	-0.8	1.2	0.4	-0.4	-0.6	0.7	0.5	-0.0
BMI with tail	2.8	9.8	12.9	-3.4	-2.9	-3.1	-3.6	3.1	2.7	-2.5	-3.5	3.5	3.5	-3.5	-3.3	0.9
BMI without tail	1.5	4.7	7.1	-2.4	-2.1	-1.8	-2.7	1.7	2.0	-2.1	-2.4	2.4	2.3	-2.4	-2.4	0.3
Body weight	7.0	30.8	41.0	-6.2	-5.7	-5.7	-6.4	5.6	5.5	-5.9	-5.8	5.8	5.8	-5.5	-4.9	2.0
Weight adjusted by age	0.6	0.9	2.8	-0.6	-0.2	-1.3	-1.3	1.2	0.1	-0.3	-0.7	0.7	0.8	-1.7	-1.3	0.2
Bone surface	0.2	0.3	1.2	-0.1	0.1	0.0	-0.5	-0.1	-0.2	0.1	-0.2	0.2	0.4	-1.0	-1.1	-1.0
Bone volume	0.3	0.6	2.8	0.2	0.5	0.1	-0.5	-0.2	-0.6	0.5	-0.3	0.3	0.4	-1.2	-1.4	-1.7
Breakpoint value in progressive ratio session	0.4	0.5	2.5	-0.4	-0.5	-0.7	-1.1	0.7	0.5	-1.6	-0.4	0.4	-0.2	-0.7	-0.2	-0.3
Number of licking bursts	0.2	0.4	1.1	0.2	0.5	-0.1	-0.4	0.1	-0.7	0.7	-0.5	0.5	0.3	-1.0	-1.1	-0.9
Context. condit. distance diff. score	0.7	0.9	2.7	-0.9	-1.3	-0.9	0.2	1.0	1.4	-0.9	-0.6	0.6	0.6	0.7	0.9	1.6
Locomotion velocity, session 1	0.8	0.8	1.8	-0.9	-0.8	-1.0	-1.3	0.9	0.7	-0.8	-0.9	0.9	1.0	-1.0	-1.0	-0.2
Locomotion distance, session 1	3.0	3.8	5.8	-2.1	-1.9	-1.9	-2.4	1.8	1.8	-2.1	-2.0	2.0	1.9	-2.1	-2.0	0.3
Locomotion velocity, session 2	0.1	0.2	0.7	-0.5	-0.5	-0.2	-0.6	0.2	0.6	-0.8	0.1	-0.1	0.2	-0.0	0.0	0.4
Locomotion distance, session 2	0.6	0.9	2.3	-0.8	-0.5	-0.6	-1.4	0.5	0.4	-1.1	-0.8	0.8	0.7	-1.5	-1.5	-0.5
Locomotion velocity, session 3	0.2	0.2	0.5	0.1	-0.1	0.4	0.3	-0.4	0.2	-0.3	0.3	-0.3	-0.6	0.7	0.7	0.7
Locomotion distance, session 3	0.3	0.4	0.6	-0.6	-0.6	-0.6	-0.5	0.6	0.6	-0.6	-0.7	0.7	0.4	-0.5	-0.4	0.8
Stereotopy head waving bouts, day 3	2.8	3.3	4.5	2.0	1.8	2.0	2.1	-2.0	-1.7	2.1	1.9	-1.9	-1.7	1.7	1.5	-0.7
Stereotopy head waving duration, day 3	0.3	0.3	0.6	0.5	0.5	0.7	0.6	-0.7	-0.5	0.8	0.5	-0.5	-0.3	0.5	0.3	-0.5
Locomotion velocity, session 7	1.5	1.6	2.4	-1.3	-1.0	-1.4	-1.5	1.4	0.9	-0.9	-1.4	1.4	1.4	-1.6	-1.3	0.3
Locomotion distance, session 7	0.4	0.5	1.0	-0.7	-0.6	-1.0	-0.7	1.0	0.6	-0.6	-0.7	0.7	0.8	-0.8	-0.6	0.2
Stereotopy head waving bouts, day 7	0.6	0.7	2.2	0.9	1.0	0.8	1.0	-0.8	-1.0	1.5	0.6	-0.6	-0.5	0.2	0.2	-0.4
Stereotopy head waving duration, day 7	0.2	0.2	0.8	0.5	0.6	0.6	0.6	-0.6	-0.6	0.9	0.4	-0.4	-0.3	0.2	0.2	-0.0
Locomotion velocity, session 8	5.9	7.1	11.0	-3.1	-3.2	-2.9	-2.6	2.9	3.2	-3.3	-2.6	2.6	2.7	-1.5	-1.2	2.0
Locomotion distance, session 8	1.3	1.9	3.2	-1.6	-1.6	-1.4	-1.4	1.4	1.5	-1.8	-1.4	1.4	1.4	-1.0	-0.9	0.6
Degree of sensitization distance	0.5	0.5	0.9	-0.8	-0.9	-0.9	-0.7	0.9	0.9	-0.7	-0.5	0.5	0.9	-0.4	-0.3	0.2
Degree of sensitization stereotypy	0.6	0.6	2.6	0.9	1.1	0.7	1.0	-0.7	-1.1	1.6	0.4	-0.4	-0.3	-0.0	-0.0	-0.5
Conditioned locomotion	0.4	0.4	0.8	0.6	0.5	0.6	0.7	-0.6	-0.4	0.3	0.9	-0.9	-0.7	0.9	0.8	0.3
Cocaine response after cond. corrected	0.6	0.7	2.9	0.7	1.1	0.3	0.6	-0.4	-1.2	1.7	-0.2	0.2	0.2	-0.9	-1.0	-0.7
Cocaine response after cond. not corrected	0.8	0.9	3.8	0.8	1.2	0.1	0.7	-0.2	-1.4	1.9	-0.4	0.4	0.3	-1.1	-1.2	-0.8
Cocaine response before conditioning	0.1	0.1	0.3	0.3	0.3	-0.0	0.5	0.1	-0.3	0.5	0.1	-0.1	-0.2	0.2	0.3	0.0
Saline control response	0.7	0.9	1.8	-0.8	-0.7	-1.1	-0.6	1.1	0.6	-0.0	-1.3	1.3	1.3	-1.3	-1.1	0.1
Bone: connectivity density	2.6	4.1	5.8	2.3	2.4	2.4	1.9	-2.4	-2.3	2.3	2.1	-2.1	-2.0	1.2	0.9	-1.3
Bone: cortical apparent density	6.4	8.7	11.8	3.3	2.8	2.9	3.4	-2.8	-2.7	2.8	3.2	-3.2	-3.3	3.2	3.1	-0.7
Bone: cortical area	0.1	0.1	0.3	0.4	0.4	0.1	0.4	-0.1	-0.4	0.5	0.1	-0.1	-0.2	-0.1	0.0	-0.6
Bone: cortical porosity	0.3	0.4	1.2	0.5	0.7	0.2	0.0	-0.3	-0.9	1.0	0.0	-0.0	0.1	-0.6	-0.8	-1.1
Bone: cortical porosity	0.4	0.4	1.3	0.1	0.4	-0.2	-0.3	0.1	-0.6	0.9	-0.3	0.3	0.7	-1.0	-1.1	-1.0
Bone: cortical thickness	1.0	1.7	3.0	1.5	1.4	1.1	1.7	-1.0	-1.3	1.7	1.2	-1.2	-1.4	1.2	1.3	-0.3
Bone: cortical thickness	4.5	5.3	7.0	2.7	2.5	2.4	2.4	-2.4	-2.4	2.2	2.5	-2.5	-2.5	2.1	1.8	-1.3
Bone: cortical tissue density	6.4	8.7	11.6	3.3	2.8	2.9	3.4	-2.9	-2.7	2.8	3.3	-3.3	-3.3	3.1	3.0	-0.8
Condit. Reinf. active minus inactive responses	1.3	1.5	2.5	1.3	1.1	1.2	1.4	-1.2	-1.0	0.7	1.4	-1.4	-1.6	1.4	1.4	0.0
Condit. Reinf. active-inactive response ratio	2.1	2.3	4.2	1.5	1.1	1.4	1.9	-1.3	-1.0	1.0	1.7	-1.7	-1.9	1.9	2.0	0.6
Condit. Reinf. active responses	1.1	1.3	2.1	1.3	1.1	1.1	1.3	-1.1	-1.1	0.9	1.3	-1.3	-1.4	1.2	1.2	-0.2
Condit. Reinf. inactive responses	0.1	0.1	0.4	0.3	0.5	0.1	-0.1	-0.1	-0.6	0.6	-0.1	0.1	0.1	-0.4	-0.5	-0.7
Incentive salience index mean	2.0	2.5	3.4	1.8	1.6	1.7	1.5	-1.7	-1.6	1.3	1.8	-1.8	-1.8	1.4	1.3	-0.9
Condit. Reinf. lever presses	1.1	1.5	2.4	1.5	1.5	1.3	0.9	-1.4	-1.5	1.3	1.3	-1.3	-1.2	0.6	0.5	-1.6
Condit. Reinf. active minus inactive responses	0.6	0.8	2.2	1.1	1.2	0.8	0.3	-0.8	-1.2	0.7	0.7	-0.7	-1.0	0.1	0.0	-1.5
Condit. Reinf. active-inactive response ratio	0.6	0.7	2.9	0.9	1.1	0.8	0.1	-0.9	-1.1	0.6	0.5	-0.5	-0.8	-0.1	-0.3	-1.7
Condit. Reinf. active responses	0.9	1.2	3.9	1.3	1.5	1.0	0.2	-1.1	-1.6	1.0	0.8	-0.8	-1.1	-0.0	-0.2	-2.0
Condit. Reinf. inactive responses	0.9	1.1	2.3	1.3	1.5	1.0	0.6	-1.1	-1.5	1.4	0.8	-0.8	-0.9	0.1	-0.1	-1.4
Condit. Reinf. lever presses	0.1	0.1	0.2	0.3	0.3	0.2	0.4	-0.2	-0.3	0.2	0.1	-0.1	-0.5	0.3	0.3	0.2
Condit. Reinf. lever reinforcers received	1.0	1.4	3.1	1.4	1.6	1.2	0.5	-1.2	-1.6	1.0	1.0	-1.0	-1.4	0.3	0.1	-1.8
Conditioned reinforcement - actives	0.1	0.2	0.7	0.4	0.4	-0.2	0.9	0.2	-0.4	0.8	0.3	-0.3	-0.2	0.2	0.4	0.2
Conditioned reinforcement - inactives	0.3	0.4	0.9	0.5	0.3	0.7	0.5	-0.7	-0.3	0.1	0.8	-0.8	-0.7	0.9	0.8	-0.5
Conditioned locomotion	0.5	0.6	2.0	0.9	1.1	0.4	0.8	-0.5	-1.1	1.4	0.8	-0.8	-0.5	0.1	0.1	0.0
Patch foraging indifference point 0 sec	1.9	3.5	7.0	1.9	1.7	2.0	2.7	-2.0	-1.5	1.4	1.9	-1.9	-2.0	2.0	1.9	-0.2
Patch foraging indifference point AUC	0.0	0.0	0.1	-0.1	-0.0	-0.1	0.1	0.1	0.0	-0.1	-0.3	0.3	0.3	-0.3	-0.2	0.4
Delay disc. indifference point, 0s delay	1.5	1.6	2.4	1.5	1.5	1.3	1.4	-1.3	-1.5	1.6	1.1	-1.1	-1.3	0.9	0.7	-0.8
Delay disc. indifference point, 16s delay	1.1	1.2	3.0	0.9	0.5	0.9	1.7	-0.8	-0.4	0.9	1.1	-1.1	-0.9	1.7	1.6	0.5
Delay disc. indifference point, 2s delay	0.8	0.9	3.3	1.1	1.3	0.4	0.9	-0.5	-1.4	1.8	0.3	-0.3	-0.4	-0.2	-0.5	-1.2
Delay disc. indifference point, 24s delay	0.1	0.2	0.9	-0.1	-0.2	0.1	0.6	-0.1	0.2	0.2	0.0	-0.0	0.1	0.7	0.4	0.9
Delay disc. indifference point, 4s delay	0.7	0.7	1.6	1.1	1.2	0.7	0.9	-0.7	-1.2	1.3	0.4	-0.4	-0.9	0.4	0.2	-0.7
Delay disc. indifference point, 8s delay	0.2	0.2	0.7	0.4	0.4	0.5	0.8	-0.5	-0.4	0.8	0.1	-0.1	-0.2	0.5	0.2	0.2
Indifference point function ln k	0.2	0.4	1.2	0.1	-0.1	0.3	0.9	-0.2	0.2	0.2	0.5	-0.5	-0.4	1.1	1.0	1.0
Indifference point function log k	0.2	0.4	1.2	0.1	-0.1	0.3	0.9	-0.2	0.2	0.2	0.5	-0.5	-0.4	1.1	1.0	1.0
Patch foraging total patch changes 0 sec	1.3	2.4	5.5	1.6	1.3	1.7	2.3	-1.6	-1.2	1.0	1.6	-1.6	-1.7	1.8	1.6	-0.0
Patch foraging total patch changes 12 sec	3.3	4.3	6.9	2.5	2.6	2.3	2.0	-2.3	-2.6	2.3	1.9	-1.9	-2.1	1.0	0.7	-1.8
Patch foraging total patch changes 18 sec	0.3	0.4	1.0	0.6	0.6	0.7	1.0	-0.7	-0.6	0.3	0.6	-0.6	-0.6	0.5	0.6	0.1
Patch foraging total patch changes 24 sec	0.6	1.1	2.8	1.2	1.3	0.7	1.3	-0.7	-1.3	1.7	0.9	-0.9	-0.9	0.6	0.7	0.3
Patch foraging total patch changes 6 sec	1.6	2.4	3.6	1.7	1.5	1.8	1.9	-1.8	-1.5	1.3	1.6	-1.6	-1.6	1.4	1.1	-1.0
Patch foraging time to switch 0 sec	0.0	0.1	0.3	0.2	0.3	0.1	-0.2	-0.1	-0.3	0.2	0.4	-0.4	-0.2	-0.2	-0.1	-0.6
Patch foraging water rate 0 sec	0.1	0.2	0.5	0.4	0.3	0.6	0.5	-0.6	-0.2	-0.1	0.2	-0.2	-0.6	0.7	0.4	-0.0
Patch foraging water rate 12 sec	0.1	0.1	0.6	-0.2	-0.3	-0.5	-0.4	0.5	0.3	-0.8	-0.1	0.1	-0.2	0.1	0.4	0.3
Patch foraging water rate 18 sec	0.2	0.4	0.8	0.7	0.9	0.7	0.3	-0.7	-0.9	0.7	0.4	-0.4	-0.6	0.1	-0.1	-0.7
Patch foraging water rate 24 sec	0.6	0.8	1.5	0.9	0.8	1.2	0.5	-1.2	-0.7	0.4	0.9	-0.9	-1.0	0.8	0.5	-1.2
Patch foraging water rate 6 sec	1.2	1.7	2.9	1.5	1.5	1.6	1.1	-1.6	-1.5	1.0	1.2	-1.2	-1.7	1.0	0.7	-1.0
Seeking ratio, delayed vs. immediate footshock	0.4	0.5	2.1	0.4	-0.1	-0.2	0.7	0.3	0.2	-0.5	0.4	-0.4	-0.9	1.3	1.5	0.6
Distance traveled before self-admin	0.3	0.3	2.4	0.0	0.1	-0.1	-0.9	-0.0	-0.2	-0.5	-0.0	0.0	-0.1	-0.5	-0.7	-1.6
Distance traveled after self-admin	0.5	0.6	1.4	-0.9	-0.9	-0.4	-1.2	0.4	0.9	-1.0	-0.8	0.8	0.7	-0.5	-0.8	-0.8
Extensor digitorum longus weight	7.5	29.5	40.6	-6.2	-6.4	-6.2	-5.2	6.3	6.3	-5.6	-5.5	5.5	5.5	-3.5	-2.4	4.4
Bone: elastic displacement	0.0	0.0	0.2	0.1	0.0	-0.0	0.4	0.1	-0.0	0.1	-0.0	0.0	0.0	0.1	0.1	0.5
Bone: elastic work	0.1	0.1	0.6	0.2	0.2	0.0	0.0	-0.0	-0.3	0.2	-0.1	0.1	-0.0	-0.4	-0.5	-0.8
Bone: endosteal estimation	2.4	5.3	7.6	-2.6	-2.2	-2.2	-2.7	2.1	2.1	-2.3	-2.3	2.3	2.8	-2.7	-2.6	0.0
Bone: endosteal perimeter	1.5	3.1	4.5	-2.0	-1.9	-1.6	-2.1	1.6	1.8	-2.1	-1.7	1.7	1.8	-1.7	-1.8	-0.3
Epididymis fat weight	0.3	1.1	2.4	-0.9	-0.7	-1.1	-1.4	1.1	0.5	-0.5	-0.9	0.9	1.1	-1.5	-1.6	-0.6
Delta time in closed arm before/after self-admin	4.3	4.0	5.3	-2.2	-2.2	-2.1	-2.3	2.1	2.1	-2.1	-2.1	2.1	2.1	-1.7	-1.3	1.2
Delta time in open arm before/after self-admin	0.0	0.0	0.1	0.0	-0.0	0.0	0.1	-0.0	0.0	-0.1	-0.2	0.2	-0.0	0.3	0.2	-0.3
Diff in mean of infusions in LGA sessions	0.1	0.2	0.6	-0.1	-0.1	-0.3	-0.8	0.3	0.1	-0.7	-0.2	0.2	-0.2	-0.6	-0.3	-0.3
Delay discount exponential model param	0.3	0.3	1.1	-0.6	-0.6	-0.5	-1.0	0.4	0.5	-1.0	-0.2	0.2	0.4	-0.7	-0.4	-0.1
Extinction: sum of active levers before priming	1.5	1.6	2.6	-1.4	-1.3	-1.4	-1.0	1.4	1.2	-0.8	-1.4	1.4	1.6	-1.3	-1.0	1.0
Active lever presses in extinction session 6	0.9	0.9	4.0	0.0	0.5	0.1	-1.0	-0.3	-0.7	0.1	-0.2	0.2	0.4	-1.7	-2.0	-1.8
Bone: final force	0.4	0.7	2.0	0.7	1.0	0.4	0.2	-0.5	-1.1	1.4	0.2	-0.2	0.1	-0.8	-0.9	-1.4
Bone: final moment	0.4	0.6	1.9	0.5	0.8	0.3	0.1	-0.4	-0.9	1.2	0.0	-0.0	0.3	-0.9	-1.0	-1.4
Food consumed during 24 hour testing period	0.6	0.9	1.2	-1.1	-1.1	-0.9	-1.1	1.0	1.0	-0.6	-1.1	1.1	1.0	-0.8	-0.8	-0.0
Glucose	0.3	0.5	1.3	-0.0	0.2	-0.6	0.0	0.6	-0.3	0.7	-1.0	1.0	0.9	-1.1	-1.2	-0.4
Heart weight	3.1	4.7	6.9	-2.4	-2.4	-2.6	-2.1	2.6	2.4	-2.4	-2.2	2.2	2.2	-1.9	-1.4	0.6
Delay discount hyperbolic model param	0.2	0.3	0.9	-0.6	-0.5	-0.4	-0.9	0.3	0.5	-0.9	-0.1	0.1	0.4	-0.5	-0.3	0.0
Intermittent access intake day 1-15 change	0.1	0.1	0.5	0.1	0.0	0.4	-0.4	-0.4	0.0	-0.7	-0.1	0.1	-0.6	0.1	0.2	-0.2
Intermittent access intake escalation	0.1	0.1	0.5	0.1	-0.0	0.4	-0.3	-0.3	0.1	-0.7	-0.1	0.1	-0.6	0.2	0.2	-0.3
Intermittent access intake escalation 2	0.3	0.3	1.0	-0.6	-0.6	-0.0	-0.9	0.1	0.6	-1.0	-0.7	0.7	0.2	-0.3	-0.4	-0.0
Intermitt. access day 1 inactive lever presses	0.5	1.8	3.2	1.4	1.3	1.7	0.7	-1.6	-1.2	0.4	1.4	-1.4	-1.8	1.3	0.9	-1.5
Intermitt. access day 15 inactive lever presses	1.2	2.5	4.2	1.6	1.4	2.1	1.7	-1.9	-1.3	1.0	1.5	-1.5	-2.0	1.8	1.7	-0.3
Intermitt. access escalation Index	1.5	2.1	3.1	-1.6	-1.5	-1.5	-1.2	1.5	1.4	-0.9	-1.8	1.8	1.7	-1.2	-1.0	1.3
Intermittent access day 1 total infusions	0.1	0.1	0.4	0.2	0.0	0.0	0.2	-0.0	-0.0	0.1	0.5	-0.5	-0.1	0.4	0.2	-0.7
Intermittent access day 15 total infusions	0.1	0.1	0.3	0.1	-0.2	0.2	0.0	-0.1	0.3	-0.5	0.1	-0.1	-0.5	0.6	0.5	-0.4
Intermittent access terminal intake (last 3 days)	0.2	0.3	0.8	0.4	0.2	0.8	0.4	-0.7	-0.1	-0.1	0.5	-0.5	-0.7	0.9	0.6	-0.6
Intermittent access total infusions	0.1	0.2	0.5	0.1	-0.1	0.3	0.2	-0.2	0.2	-0.4	0.4	-0.4	-0.4	0.7	0.6	-0.6
Intermittent access day 1 locomotion	0.1	0.2	0.5	0.3	0.2	0.0	0.5	-0.1	-0.2	0.5	0.7	-0.7	-0.1	0.4	0.3	-0.2
Intermittent access day 15 total locomotion	0.2	0.3	0.8	0.6	0.7	0.3	0.3	-0.4	-0.7	0.9	0.7	-0.7	-0.3	-0.0	-0.2	-0.7
Intermittent access total locomotion	0.9	1.0	1.6	1.1	1.0	0.9	1.2	-0.9	-1.0	1.2	1.3	-1.3	-0.9	0.9	0.7	-0.6
Intermittent access standard deviation	1.0	2.0	4.0	1.3	1.1	1.9	0.8	-1.8	-1.0	-0.0	1.5	-1.5	-2.0	1.5	1.2	-1.4
Left kidney weight	0.4	1.7	5.0	-1.6	-1.7	-0.8	-1.9	0.8	1.7	-2.2	-0.9	0.9	1.0	-0.7	-0.5	0.8
Right kidney weight	0.1	0.5	1.8	-0.5	-0.2	0.1	-1.3	-0.2	0.2	-0.8	-0.4	0.4	0.4	-1.0	-1.1	-0.9
Cocaine induced anxiety	2.7	3.8	5.2	-2.3	-2.1	-1.8	-2.2	1.8	2.1	-2.2	-2.2	2.2	1.8	-1.8	-1.5	1.2
Post-drug Anxiety	0.8	0.8	1.4	-1.1	-1.0	-0.7	-0.7	0.7	1.1	-1.1	-1.1	1.1	0.7	-0.5	-0.3	1.2
Baseline Anxiety	1.8	2.0	4.4	1.7	1.7	1.1	2.1	-1.1	-1.7	2.1	1.3	-1.3	-1.2	1.1	1.0	-0.4
Tail length	0.4	1.7	5.4	-1.5	-1.6	-1.2	-1.3	1.2	1.7	-2.3	-0.8	0.8	0.7	-0.6	-0.2	1.3
Length with tail	2.5	10.8	22.0	-3.7	-3.6	-3.4	-4.0	3.3	3.6	-4.7	-3.0	3.0	2.7	-2.7	-2.2	1.5
Length without tail	3.1	9.9	12.9	-3.5	-3.2	-3.5	-3.6	3.5	3.1	-3.4	-3.2	3.2	3.2	-3.1	-2.6	1.3
Times rat made contact with spout	0.6	0.7	2.0	0.9	1.0	0.9	0.5	-0.9	-1.1	1.4	0.5	-0.5	-0.5	0.1	-0.2	-1.3
Lifetime Intake	0.2	0.3	0.8	0.4	0.1	0.4	0.4	-0.4	-0.0	-0.3	0.6	-0.6	-0.7	0.9	0.8	-0.6
Liver weight, left	0.4	0.7	1.5	-0.8	-0.6	-0.9	-1.0	0.9	0.5	-0.3	-0.8	0.8	1.0	-1.2	-1.1	0.1
Liver weight, right	0.5	0.8	1.4	0.7	0.6	1.2	1.1	-1.2	-0.6	1.0	1.1	-1.1	-0.6	1.0	0.7	0.2
Locomotor activity	0.3	0.5	1.4	0.6	1.0	0.4	0.1	-0.5	-1.1	1.2	0.2	-0.2	-0.2	-0.6	-0.8	-1.2
Locomotor testing distance	1.5	2.7	5.0	1.8	2.0	1.8	1.7	-1.8	-2.0	2.2	1.5	-1.5	-1.4	0.9	0.5	-1.1
Locomotor testing rearing	5.0	10.0	14.0	3.3	3.1	3.7	3.6	-3.7	-2.9	2.8	3.5	-3.5	-3.3	3.1	2.4	-1.2
Locomotion in novel chamber	3.7	4.7	7.4	2.7	2.7	1.8	2.0	-1.9	-2.7	2.6	2.3	-2.3	-2.0	1.0	0.8	-2.3
Locomotion in novel chamber post-restriction	0.3	0.5	2.7	0.4	0.7	0.4	-0.2	-0.5	-0.8	0.4	-0.2	0.2	-0.1	-0.8	-1.2	-1.6
Fecal boli incidents, locomotor time 1	0.2	0.3	0.6	-0.5	-0.5	-0.7	-0.6	0.7	0.4	-0.4	-0.3	0.3	0.7	-0.6	-0.6	0.2
Change in fecal boli incidents, locomotor task	0.1	0.1	0.4	0.3	0.3	-0.1	0.6	0.1	-0.3	0.7	-0.1	0.1	-0.1	-0.0	0.1	-0.2
Time >=10cm from walls, locomotor time 1	0.6	0.6	2.0	0.7	0.5	0.0	1.4	0.0	-0.4	0.9	0.8	-0.8	-0.6	0.8	1.2	1.1
Bouts of movement, locomotor time 1	0.4	0.5	0.9	-0.9	-0.7	-0.4	-0.9	0.4	0.7	-0.9	-0.5	0.5	0.7	-0.5	-0.7	0.6
Total resting periods, locomotor time 1	0.9	1.0	1.7	-1.3	-1.0	-0.9	-1.3	0.8	0.9	-1.1	-0.9	0.9	1.2	-1.0	-1.1	0.5
Rest time, locomotor task time 1	0.1	0.2	0.9	-0.2	-0.0	0.2	-0.4	-0.3	-0.0	-0.1	0.5	-0.5	0.2	-0.2	-0.5	-1.0
Distance moved, locomotor task time 1	0.1	0.1	0.3	0.2	0.1	-0.5	0.4	0.6	-0.1	0.3	-0.5	0.5	0.0	-0.1	0.2	0.5
Vertical activity count, locomotor time 1	0.4	1.0	2.5	-0.4	-0.5	-1.6	-0.3	1.6	0.4	-0.2	-1.5	1.5	0.6	-1.0	-0.4	0.8
Time >=10cm from walls, locomotor time 2	0.6	0.8	2.8	1.2	1.2	-0.1	1.2	-0.0	-1.3	1.7	0.7	-0.7	-0.6	-0.0	0.4	-0.1
Bouts of movement, locomotor time 2	0.6	1.0	1.8	0.6	0.5	1.2	0.7	-1.2	-0.5	0.2	1.4	-1.4	-1.0	1.3	1.2	0.7
Total resting periods, locomotor time 2	0.4	0.8	1.6	0.4	0.3	1.0	0.5	-1.0	-0.2	-0.1	1.2	-1.2	-0.9	1.2	1.2	0.8
Rest time, locomotor task time 2	0.6	0.8	1.3	-1.0	-1.0	-1.1	-1.0	1.1	1.0	-1.1	-0.7	0.7	0.8	-0.8	-0.6	0.4
Distance moved, locomotor task time 2	0.3	0.4	0.8	-0.3	-0.3	-0.8	-0.2	0.8	0.3	0.2	-0.9	0.9	0.8	-0.8	-0.6	0.3
Vertical activity count, locomotor time 2	0.6	0.8	1.9	-0.6	-0.6	-1.4	-0.2	1.4	0.6	-0.2	-1.3	1.3	0.8	-0.8	-0.4	0.9
Light reinforcement 1	1.5	3.7	5.6	2.1	2.1	2.4	1.9	-2.4	-2.0	1.5	2.0	-2.0	-2.1	1.4	0.9	-1.6
Light reinforcement 2	0.3	0.5	2.1	0.6	0.8	0.8	0.1	-0.8	-0.9	0.7	0.3	-0.3	-0.2	-0.3	-0.9	-1.4
Bone: marrow area	2.3	5.0	7.1	-2.5	-2.2	-2.1	-2.6	2.0	2.0	-2.3	-2.1	2.1	2.7	-2.5	-2.5	0.0
Bone: maximum diameter	0.1	0.1	0.8	0.0	0.1	0.0	-0.4	-0.1	-0.2	-0.2	-0.0	0.0	0.1	-0.5	-0.5	-0.9
Bone: maximum force	0.2	0.4	1.2	-0.4	-0.2	-0.5	-0.6	0.4	0.1	0.0	-0.6	0.6	0.8	-1.1	-1.0	-0.6
Bone: maximum moment	0.3	0.5	1.3	-0.6	-0.4	-0.6	-0.6	0.5	0.3	-0.1	-0.7	0.7	0.9	-1.1	-1.1	-0.5
Mean time between licks in bursts	0.8	2.0	2.8	-1.7	-1.6	-1.3	-1.6	1.3	1.5	-1.7	-1.4	1.4	1.5	-1.2	-1.2	0.4
Mean num. licks in bursts	0.3	0.4	1.0	0.5	0.3	0.8	0.7	-0.7	-0.2	0.3	0.8	-0.8	-0.6	1.0	0.8	-0.2
Cd content in liver	1.1	1.3	2.2	-1.3	-1.4	-1.1	-1.1	1.2	1.4	-1.5	-1.0	1.0	1.1	-0.8	-0.7	0.5
Co content in liver	1.1	1.3	2.7	-1.3	-1.6	-1.1	-0.8	1.1	1.6	-1.6	-0.7	0.7	0.8	-0.0	0.3	1.4
Cu content in liver	0.3	0.3	1.0	0.2	-0.1	0.3	0.5	-0.2	0.2	-0.9	0.6	-0.6	-0.9	0.8	1.0	0.3
Fe content in liver	2.0	2.5	3.1	-1.7	-1.5	-1.6	-1.8	1.6	1.4	-1.4	-1.8	1.8	1.7	-1.7	-1.6	0.1
K content in liver	1.1	1.0	1.7	1.0	0.9	1.1	1.2	-1.1	-0.8	0.4	1.2	-1.2	-1.3	1.1	1.1	-0.1
Mg content in liver	2.1	2.2	4.6	1.1	0.8	1.3	1.9	-1.3	-0.6	0.5	1.7	-1.7	-1.6	2.1	2.1	1.0
Mn content in liver	2.1	2.3	4.2	1.4	1.0	1.4	1.9	-1.4	-0.9	0.4	1.8	-1.8	-1.9	2.1	2.0	0.4
Na content in liver	0.6	0.6	2.5	0.1	0.6	-0.0	-0.7	-0.0	-0.7	0.3	-0.4	0.4	0.3	-1.2	-1.4	-1.6
Rb content in liver	1.8	2.1	4.3	1.5	1.3	1.6	2.1	-1.6	-1.3	1.5	1.4	-1.4	-1.4	1.4	1.2	-0.5
Se content in liver	6.9	8.2	11.3	3.2	3.0	3.2	2.9	-3.2	-2.8	2.1	3.2	-3.2	-3.4	2.6	2.3	-1.5
Sr content in liver	0.6	0.5	1.7	-0.1	-0.4	0.0	0.3	0.1	0.6	-1.1	0.7	-0.7	-0.7	1.2	1.3	0.9
Zn content in liver	3.3	3.6	5.3	2.1	1.9	2.3	1.7	-2.3	-1.8	1.3	2.2	-2.2	-2.2	1.7	1.4	-1.2
Bone: minimum diameter	0.6	1.2	1.7	-1.1	-1.1	-1.1	-0.9	1.1	1.0	-1.0	-1.2	1.2	1.3	-1.3	-1.2	-0.3
Time in familiar zone, hab. session 1	0.9	0.8	3.6	0.1	0.4	-0.1	-0.9	0.0	-0.6	0.4	-0.6	0.6	0.6	-1.3	-1.7	-1.9
Time in novel zone, hab. session 1	1.7	1.7	4.1	1.0	0.7	1.0	2.0	-0.9	-0.5	0.7	1.2	-1.2	-1.4	1.8	2.0	1.4
Total zone transitions, hab. session 1	1.5	2.0	2.9	-1.6	-1.7	-1.6	-1.5	1.6	1.7	-1.7	-1.4	1.4	1.3	-0.9	-0.6	1.0
Total locomotion distance, hab. session 1	0.0	0.0	0.1	0.0	-0.1	-0.1	0.1	0.2	0.2	-0.0	-0.1	0.1	-0.3	0.3	0.4	0.1
Locomotion velocity, hab. session 1	0.2	0.3	0.5	-0.6	-0.7	-0.7	-0.6	0.7	0.7	-0.6	-0.5	0.5	0.2	-0.2	0.0	0.3
Time in familiar zone, hab. session 2	0.3	0.3	1.3	0.6	0.7	0.5	0.3	-0.5	-0.8	0.5	0.1	-0.1	-0.3	-0.3	-0.4	-1.1
Time in novel zone, hab. session 2	0.3	0.3	0.7	0.5	0.4	0.5	0.5	-0.5	-0.3	0.3	0.7	-0.7	-0.7	0.8	0.8	0.6
Total zone transitions, hab. session 2	1.1	1.4	2.0	-1.2	-1.2	-1.4	-0.9	1.4	1.1	-0.9	-1.4	1.4	1.3	-1.1	-0.9	0.8
Total locomotion distance, hab. session 2	0.5	0.7	1.3	-0.7	-0.6	-0.9	-0.8	0.9	0.5	-0.3	-1.1	1.1	0.8	-1.1	-1.0	-0.1
Locomotion velocity, hab. session 2	0.8	1.0	1.8	-0.9	-0.8	-1.2	-1.0	1.2	0.7	-0.5	-1.3	1.3	1.0	-1.2	-1.1	0.1
Novel to familiar place preference ratio	0.7	0.7	2.6	-1.0	-1.1	-0.8	-0.6	0.8	1.1	-1.2	-0.3	0.3	0.4	0.2	0.5	1.6
Novelty place preference	0.6	0.7	3.1	-0.8	-1.0	-0.6	-0.3	0.6	1.0	-1.0	-0.1	0.1	0.3	0.5	0.8	1.8
Time in novel zone, NPP test	0.4	0.4	2.5	-0.4	-0.5	-0.4	0.1	0.4	0.6	-0.4	0.1	-0.1	0.0	0.6	0.9	1.6
Total zone transitions, NPP test	1.0	1.5	3.0	-1.0	-0.8	-1.3	-1.3	1.3	0.7	-0.4	-1.5	1.5	1.5	-1.7	-1.7	-0.4
Total locomotion distance, NPP test	0.3	0.4	1.3	-0.3	-0.2	-0.4	-0.4	0.4	0.1	0.3	-0.8	0.8	0.7	-1.1	-1.1	-0.8
Locomotion velocity, NPP test	0.5	0.7	1.2	-0.8	-0.7	-0.7	-0.9	0.7	0.7	-0.4	-0.9	0.9	1.0	-1.0	-1.1	-0.7
Intraocular pressure	1.9	2.7	4.2	-2.0	-2.0	-1.8	-1.5	1.8	2.0	-1.4	-1.5	1.5	2.0	-1.2	-1.0	1.0
Delta distance traveled before/after self-admin	0.9	0.9	1.8	-1.1	-1.2	-0.9	-0.4	1.0	1.3	-0.7	-1.0	1.0	0.9	-0.3	-0.1	1.3
Delta ambulatory time before/after self-admin	1.1	1.4	2.1	-1.4	-1.3	-1.0	-0.7	1.1	1.2	-0.5	-1.4	1.4	1.5	-0.9	-0.8	1.4
Parametrial fat weight	0.3	0.6	2.2	0.7	1.0	0.8	-0.2	-0.9	-1.1	0.5	0.3	-0.3	-0.4	-0.5	-0.9	-1.5
Pavlov. Cond. lever latency	1.5	1.9	4.9	-1.5	-1.8	-1.4	-0.7	1.5	1.9	-1.8	-1.0	1.0	0.8	0.3	0.6	2.2
Pavlov. Cond. magazine entry latency	7.4	9.5	14.9	3.6	3.8	3.3	2.4	-3.4	-3.9	3.7	3.0	-3.0	-2.7	1.3	0.7	-3.5
Pavlov. Cond. change in total contacts	9.1	9.7	12.2	3.5	3.3	3.5	3.2	-3.4	-3.2	3.1	3.4	-3.4	-3.2	2.6	2.2	-1.9
Pavlov. Cond. index score	6.1	7.7	12.9	3.2	3.5	2.9	2.2	-3.0	-3.6	3.5	2.5	-2.5	-2.3	0.8	0.3	-3.4
Pavlov. Cond. latency score	4.5	5.7	10.1	2.7	3.1	2.5	1.8	-2.6	-3.2	3.1	2.1	-2.1	-1.8	0.5	-0.0	-3.1
Pavlov. Cond. lever contacts	2.1	2.5	6.1	1.7	2.1	1.6	0.7	-1.7	-2.2	1.9	1.2	-1.2	-1.0	-0.2	-0.5	-2.5
Pavlov. Cond. magazine entry number	10.5	13.2	19.2	-4.2	-4.3	-4.0	-3.4	4.0	4.3	-4.4	-3.6	3.6	3.3	-2.1	-1.5	3.3
Pavlov. Cond. intertrial magazine entries	1.0	1.2	4.4	-1.2	-1.3	-1.2	-0.6	1.2	1.4	-1.2	-0.7	0.7	0.8	-0.1	0.2	2.1
Pavlov. Cond. lever-magazine prob. diff.	7.5	9.2	14.8	3.5	3.8	3.3	2.4	-3.3	-3.8	3.7	2.8	-2.8	-2.6	1.1	0.6	-3.5
Pavlov. Cond. response bias	8.2	10.1	14.6	3.7	3.8	3.5	2.8	-3.5	-3.8	3.7	3.2	-3.2	-2.9	1.7	1.1	-3.2
Pavlov. Cond. lever latency	0.3	0.4	0.9	-0.7	-0.8	-0.6	-0.3	0.6	0.9	-0.9	-0.2	0.2	0.5	-0.1	0.2	1.0
Pavlov. Cond. magazine entry latency	0.2	0.3	0.6	-0.3	-0.1	-0.7	-0.5	0.7	0.1	-0.2	-0.8	0.8	0.4	-0.7	-0.6	-0.2
Pavlov. Cond. change in total contacts	0.5	0.8	1.2	1.1	1.0	0.9	0.9	-0.9	-0.9	0.8	0.9	-0.9	-1.1	0.9	0.8	-0.6
Pavlov. Cond. index score	0.1	0.1	0.5	0.3	0.5	0.2	0.1	-0.2	-0.5	0.5	-0.2	0.2	-0.1	-0.3	-0.4	-0.7
Pavlov. Cond. latency score	0.1	0.1	0.3	0.3	0.4	0.0	0.0	-0.0	-0.5	0.5	-0.3	0.3	0.0	-0.3	-0.4	-0.6
Pavlov. Cond. lever contacts	0.3	0.4	1.3	0.7	0.8	0.6	0.3	-0.6	-0.9	1.0	0.1	-0.1	-0.4	-0.1	-0.4	-1.1
Pavlov. Cond. magazine entry number	0.0	0.1	0.2	-0.3	-0.3	0.1	-0.1	-0.1	0.4	-0.3	0.3	-0.3	0.0	0.3	0.2	0.3
Pavlov. Cond. intertrial magazine entries	0.8	1.2	4.1	-1.2	-1.5	-1.0	-0.5	1.1	1.6	-1.4	-0.4	0.4	0.4	0.4	0.8	2.0
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.4	0.2	0.3	0.0	-0.1	-0.0	-0.4	0.3	-0.3	0.3	-0.0	-0.3	-0.4	-0.6
Pavlov. Cond. response bias	0.6	0.8	2.3	1.0	1.2	0.8	0.4	-0.8	-1.3	1.1	0.3	-0.3	-0.7	-0.0	-0.3	-1.5
Time in closed arm before self-admin	3.1	4.0	6.4	1.7	1.4	2.5	2.4	-2.5	-1.2	1.5	2.3	-2.3	-1.9	2.5	1.9	-0.4
Time in closed arm after self-admin	0.5	0.6	2.0	-0.1	-0.5	0.5	0.6	-0.4	0.7	-0.5	0.7	-0.7	-0.5	1.4	1.4	0.9
Time in open arm before self-admin	2.3	2.5	5.0	-1.4	-1.3	-2.2	-1.5	2.2	1.2	-1.3	-1.8	1.8	1.3	-1.9	-1.1	0.6
Time in open arm after self-admin	0.4	0.5	1.0	-0.5	-0.5	-0.9	-0.6	0.9	0.4	-0.7	-1.0	1.0	0.5	-0.7	-0.4	-0.1
Bone: periosteal estimation	0.5	1.1	2.3	-1.0	-0.8	-0.9	-1.1	0.9	0.6	-0.8	-1.0	1.0	1.3	-1.5	-1.5	-0.6
Bone: periosteal perimeter	1.3	2.2	3.5	-1.4	-1.2	-1.3	-1.8	1.3	1.0	-1.2	-1.7	1.7	1.6	-1.8	-1.9	-1.0
Bone: post-yield work	0.9	1.3	2.0	-1.4	-1.4	-1.0	-1.3	1.1	1.4	-1.2	-1.1	1.1	1.3	-0.8	-0.7	0.5
Progressive ratio test 1 active lever presses	0.1	0.2	0.6	0.3	0.2	0.3	0.8	-0.4	-0.2	0.6	0.4	-0.4	-0.1	0.4	0.2	0.0
Progressive ratio test 1 breakpoint	0.1	0.1	0.6	0.2	0.1	0.3	0.7	-0.3	-0.1	0.5	0.3	-0.3	-0.0	0.4	0.2	0.1
Progressive ratio test 1 inactive lever presses	0.3	0.4	1.0	0.5	0.3	0.8	0.6	-0.7	-0.2	-0.1	0.7	-0.7	-0.8	1.0	0.8	-0.3
Progressive ratio test 2 active lever presses	0.8	0.9	1.2	1.1	1.0	0.9	0.8	-0.9	-1.0	0.7	1.1	-1.1	-1.1	0.8	0.6	-1.0
Progressive ratio test 2 breakpoint	0.8	0.9	1.3	1.1	1.1	0.9	0.8	-1.0	-1.1	0.7	1.1	-1.1	-1.1	0.8	0.6	-1.1
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.6	0.4	0.3	0.4	0.1	-0.4	-0.3	-0.1	0.6	-0.6	-0.6	0.5	0.4	-0.8
Incentive Sensitization - Responses	1.0	1.4	2.7	1.4	1.4	1.2	0.5	-1.3	-1.5	0.8	1.3	-1.3	-1.3	0.7	0.4	-1.6
Incentive Sensitization - Breakpoint	1.0	1.3	2.7	1.4	1.4	1.1	0.4	-1.2	-1.4	0.7	1.3	-1.3	-1.2	0.6	0.3	-1.6
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.2	0.1	0.2	0.0	0.0	-0.1	-0.3	0.5	0.1	-0.1	0.2	-0.4	-0.5	-0.3
Progressive ratio	0.0	0.1	0.3	0.1	0.2	-0.3	-0.3	0.2	-0.3	-0.1	-0.1	0.1	-0.1	-0.5	-0.3	0.0
Food seeking constrained by brief footshock	0.4	0.4	1.0	0.5	0.7	1.0	0.3	-1.0	-0.7	0.6	0.6	-0.6	-0.4	0.1	-0.3	-1.0
Seeking ratio, punishment vs. effort	0.1	0.1	0.4	0.0	-0.0	0.6	0.5	-0.5	0.0	0.5	0.3	-0.3	0.1	0.6	0.3	-0.0
Retroperitoneal fat weight	0.1	0.2	0.6	0.4	0.4	0.7	0.4	-0.8	-0.4	0.2	0.7	-0.7	-0.3	0.3	0.1	-0.4
Reaction time number correct	0.9	1.7	2.6	-1.1	-1.1	-1.6	-1.6	1.6	1.0	-0.8	-1.5	1.5	1.2	-1.4	-1.2	-0.7
Reaction time mean minus median	0.2	0.4	1.2	-0.6	-0.6	-0.9	-0.6	0.9	0.6	-0.1	-0.7	0.7	0.6	-0.5	-0.2	1.1
Reaction time mean minus median AUC	0.0	0.1	0.5	-0.0	0.1	-0.3	0.0	0.3	-0.1	0.7	-0.4	0.4	0.3	-0.3	-0.1	0.6
Reaction time num false alarms	0.5	0.7	3.9	0.7	0.9	0.4	0.0	-0.5	-1.0	1.1	0.3	-0.3	-0.1	-0.6	-0.8	-2.0
Reaction time num false alarms AUC	0.4	0.6	3.2	0.5	0.8	0.2	-0.2	-0.3	-0.9	0.9	0.0	-0.0	-0.1	-0.7	-0.9	-1.8
Reaction time trials correct on left	0.9	1.7	2.6	-1.1	-1.1	-1.6	-1.6	1.6	1.0	-0.8	-1.5	1.5	1.2	-1.4	-1.2	-0.7
Reaction time trials on left	0.8	1.6	2.5	-1.1	-1.1	-1.5	-1.6	1.6	1.0	-0.8	-1.5	1.5	1.2	-1.4	-1.2	-0.7
Reaction time mean	0.4	0.6	1.4	0.7	0.5	0.7	0.6	-0.6	-0.4	0.1	0.9	-0.9	-1.1	1.1	1.2	0.6
Reaction time mean AUC	0.4	0.6	1.4	0.6	0.5	0.7	0.7	-0.7	-0.4	0.0	1.0	-1.0	-1.1	1.1	1.2	0.7
Median of all reaction times	1.2	1.7	3.1	1.3	1.1	1.4	1.1	-1.3	-1.0	0.4	1.6	-1.6	-1.8	1.6	1.5	0.1
Reaction time omissions	0.3	0.4	0.7	0.8	0.8	0.7	0.4	-0.7	-0.7	0.6	0.8	-0.8	-0.9	0.6	0.4	-0.3
Reaction time false alarm rate	0.7	1.0	1.8	1.0	1.3	1.0	0.6	-1.1	-1.3	1.3	0.8	-0.8	-0.7	0.1	-0.1	-1.3
Reaction time premature initiation rate	0.1	0.2	0.5	0.5	0.7	0.2	0.2	-0.3	-0.7	0.4	0.2	-0.2	-0.6	-0.2	-0.1	-0.6
Reaction time premature initiations	0.2	0.4	0.9	-0.4	-0.2	-0.8	-0.8	0.8	0.2	-0.3	-0.8	0.8	0.3	-0.9	-0.7	-0.7
Std. dev. reaction times	0.0	0.1	0.5	0.0	0.1	-0.2	-0.1	0.2	-0.1	0.2	-0.0	0.0	-0.1	-0.1	0.1	0.7
Reaction time trials completed	0.8	1.6	2.5	-1.1	-1.1	-1.5	-1.6	1.6	1.0	-0.8	-1.5	1.5	1.2	-1.4	-1.2	-0.7
Reaction time trials AUC	0.7	1.4	2.5	-1.0	-1.0	-1.5	-1.4	1.6	0.9	-0.7	-1.4	1.4	1.1	-1.3	-1.0	-0.5
Run reversals in cocaine runway, females	1.3	1.3	2.5	-1.1	-1.5	-1.3	-0.3	1.4	1.6	-1.3	-1.2	1.2	0.7	-0.0	0.7	1.2
Run reversals in cocaine runway, males	0.2	0.2	0.6	0.5	0.5	0.5	0.4	-0.4	-0.5	0.8	0.2	-0.2	-0.3	0.2	0.0	-0.5
Latency to leave start box in cocaine runway	1.0	1.1	2.5	-1.1	-1.4	-1.2	-1.1	1.2	1.5	-1.6	-1.0	1.0	0.8	-0.4	-0.2	0.1
Latency to leave start box in cocaine runway, F	1.8	2.1	3.2	-1.5	-1.7	-1.8	-1.7	1.8	1.6	-1.7	-1.4	1.4	1.3	-1.0	-0.7	-0.1
Latency to leave start box in cocaine runway, M	0.4	0.4	0.9	0.4	0.1	0.7	0.6	-0.7	-0.0	-0.3	0.7	-0.7	-0.8	1.0	0.9	0.1
Std. dev. time between licks in bursts	0.1	0.2	0.5	-0.5	-0.3	-0.2	-0.7	0.2	0.3	-0.4	-0.4	0.4	0.4	-0.6	-0.7	-0.3
Total sessions with >9 infusions	0.6	0.7	2.1	0.6	0.2	0.7	1.2	-0.6	-0.0	-0.1	0.8	-0.8	-1.0	1.5	1.5	0.1
Short access day 1 total inactive lever presses	1.5	2.0	2.8	1.6	1.4	1.6	1.2	-1.6	-1.3	1.0	1.6	-1.6	-1.7	1.4	1.1	-1.2
Short access day 10 total inactive lever presses	0.1	0.2	0.9	-0.1	-0.2	0.0	-0.6	0.0	0.2	-0.9	-0.6	0.6	-0.5	0.0	0.2	0.2
Short access day 1 total infusions	0.7	1.0	2.5	0.8	0.4	1.0	1.2	-0.9	-0.2	0.2	1.1	-1.1	-1.0	1.6	1.5	-0.2
Short access day 10 total infusions	0.5	0.6	1.0	0.7	0.6	0.9	0.9	-0.8	-0.5	0.5	0.9	-0.9	-0.7	0.9	0.6	-1.0
Short access total infusions	0.4	0.5	1.1	0.6	0.4	0.7	0.8	-0.6	-0.3	-0.1	0.9	-0.9	-0.9	1.0	0.9	-0.8
Short access day 1 locomotion	1.3	1.6	2.2	1.3	1.0	1.4	1.5	-1.3	-0.9	0.8	1.5	-1.5	-1.3	1.5	1.3	-1.0
Short access day 10 total locomotion	1.1	2.0	4.1	1.6	1.7	1.5	1.5	-1.5	-1.7	2.0	1.4	-1.4	-1.1	0.8	0.4	-1.1
Short access total locomotion	0.4	0.5	0.8	0.7	0.5	0.7	0.9	-0.7	-0.5	0.5	0.9	-0.9	-0.7	0.9	0.7	-0.6
One hour access (0.3 mA shock)	0.2	0.3	0.7	-0.4	-0.5	-0.8	0.0	0.9	0.5	-0.3	-0.5	0.5	0.4	-0.2	0.2	0.8
Compulsive drug intake	0.9	1.1	4.8	0.0	-0.4	0.0	1.7	0.2	0.5	0.3	-0.2	0.2	-0.3	1.4	1.9	2.2
One hour access (shock baseline)	0.1	0.1	0.4	-0.1	-0.1	-0.2	-0.6	0.1	0.1	-0.5	0.1	-0.1	-0.0	-0.3	-0.3	-0.7
Social response proportion	0.3	0.3	0.8	-0.6	-0.5	-0.7	-0.0	0.7	0.5	-0.2	-0.4	0.4	0.9	-0.5	-0.3	0.9
Social responses	0.1	0.1	0.8	-0.0	0.1	0.1	0.1	-0.1	-0.2	0.1	-0.4	0.4	0.4	-0.7	-0.9	-0.2
Social time	0.8	1.1	3.5	-0.6	-0.1	-0.7	-1.1	0.6	-0.0	-0.3	-1.3	1.3	1.0	-1.9	-1.8	-0.6
Soleus weight	0.4	1.2	3.9	-0.4	0.2	-0.7	-1.0	0.6	-0.4	1.2	-1.0	1.0	1.5	-1.8	-2.0	-0.5
Bone: stiffness	0.1	0.2	0.7	-0.2	-0.1	-0.2	-0.5	0.2	0.0	0.1	-0.3	0.3	0.4	-0.6	-0.7	-0.9
Tibialis anterior weight	1.6	5.3	7.3	-2.6	-2.4	-2.5	-2.7	2.4	2.2	-1.8	-2.5	2.5	2.6	-2.2	-1.9	1.1
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.4	0.1	0.2	0.4	-0.1	-0.4	-0.2	0.4	-0.3	0.3	0.2	-0.2	-0.6	-0.6
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.8	-0.0	0.3	-0.3	-0.4	0.1	-0.4	0.3	-0.4	0.4	0.3	-0.9	-0.8	0.2
Time to tail flick, test, before self-admin	1.1	1.2	1.6	-1.2	-1.0	-1.2	-0.9	1.2	0.9	-0.7	-1.3	1.3	1.2	-1.1	-0.9	1.2
Time to tail flick, test, after self-admin	0.4	0.4	2.1	0.1	0.3	0.4	-0.5	-0.5	-0.3	0.3	-0.0	0.0	0.3	-0.6	-1.1	-1.4
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	1.4	0.3	0.7	-0.1	-0.5	-0.0	-0.9	0.6	-0.1	0.1	0.2	-1.1	-1.2	-0.9
Delta time to tail flick, test, before/after SA	2.2	2.2	4.2	1.7	1.6	1.7	1.1	-1.7	-1.6	1.4	1.6	-1.6	-1.3	0.8	0.4	-2.1
Tibia length	2.1	5.7	9.0	-2.5	-2.1	-2.4	-2.6	2.4	1.9	-1.5	-2.8	2.8	3.0	-2.7	-2.7	0.2
Ambulatory time before self-admin	0.1	0.2	1.4	-0.1	-0.1	-0.0	-0.7	-0.0	0.1	-0.8	0.0	-0.0	-0.2	-0.1	-0.2	-1.2
Ambulatory time after self-admin	1.7	2.0	3.9	-1.7	-1.5	-1.0	-2.0	1.0	1.5	-1.6	-1.5	1.5	1.4	-1.2	-1.5	-0.5
Bone: tissue strength	1.0	1.0	1.4	-1.2	-1.2	-1.1	-0.8	1.2	1.1	-0.8	-1.1	1.1	1.1	-0.6	-0.4	1.1
Total heroin consumption	1.7	2.0	8.8	1.4	1.7	1.1	-0.2	-1.2	-1.8	1.0	1.1	-1.1	-1.0	-0.7	-1.0	-3.0
Bone: trabecular number	3.7	6.1	10.1	2.9	3.1	2.7	2.1	-2.8	-3.2	3.0	2.4	-2.4	-2.1	0.9	0.4	-2.4
Bone: trabecular spacing	2.5	3.3	4.7	-1.8	-1.6	-1.9	-2.1	1.9	1.4	-1.1	-2.2	2.2	2.1	-2.1	-2.0	-0.1
Bone: trabecular thickness	0.0	0.1	0.1	0.3	0.3	0.3	-0.1	-0.3	-0.3	0.2	0.1	-0.1	-0.2	-0.1	-0.1	-0.4
Bone: trabecular tissue density	0.8	1.2	5.0	0.2	-0.2	0.1	1.3	-0.1	0.4	-0.2	0.9	-0.9	-0.8	1.6	2.0	2.2
Water consumed over 24 hours	0.3	0.4	0.8	-0.5	-0.4	-0.5	-0.6	0.5	0.3	0.0	-0.9	0.9	0.6	-0.8	-0.7	-0.6
Number of responses in last shaping day	0.8	0.9	2.5	0.6	0.2	1.1	1.1	-0.9	-0.0	-0.2	1.0	-1.0	-1.1	1.5	1.6	0.0