Hub : Genes

Ormdl3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ormdl3 0.06 0.04 7.4e-09 0.06 0.08 0.06 0.07 1.1e-07 8.5e-09 1.3e-07 7.8e-08
2 Brain gene expression Ormdl3 0.05 0.04 5.9e-04 0.02 0.03 0.01 0.03 7.1e-03 1.2e-03 6.5e-02 1.0e-03
3 Adipose isoform ratio NM_001413293.1 0.1 0.12 1.8e-06 0.06 0.04 0.06 0.06 4.7e-07 2.3e-05 2.8e-07 1.0e-06
4 Adipose isoform ratio NM_001413294.1 0.16 0.24 6.9e-07 0.06 0.04 0.06 0.06 5.6e-07 1.2e-05 1.8e-07 5.5e-07
5 Liver mRNA stability Ormdl3 0.04 0.03 8.8e-05 0.04 0.02 0.04 -0 2.8e-05 1.4e-03 8.2e-05 9.7e-01
6 NAcc gene expression Ormdl3 0.04 0.03 8.2e-05 0.04 0.02 0.03 0.03 3.0e-05 9.3e-04 1.1e-04 1.8e-04
7 Brain mRNA stability Ormdl3 0.04 0.03 3.7e-04 0.04 0.03 0.03 0.03 1.0e-04 5.3e-04 7.0e-04 6.5e-04
8 Liver gene expression Ormdl3 0.06 0.04 2.5e-04 0.01 0.01 0.02 0.01 2.3e-02 2.2e-02 1.8e-03 6.9e-02
9 Adipose gene expression Ormdl3 0.37 0.11 0.0e+00 0.22 0.2 0.28 0.24 2.4e-24 6.2e-22 6.7e-31 7.8e-26

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.62.74.81.91.82.2-2.01.6-1.61.5-1.0-0.4
Area under the delay curve0.20.20.40.60.60.5-0.40.7-0.20.4-0.5-0.5
BMI with tail2.89.211.9-3.1-3.2-2.62.7-3.53.2-3.32.82.8
BMI without tail0.10.10.3-0.4-0.40.1-0.0-0.50.3-0.60.00.2
Body weight5.824.230.2-5.4-5.5-4.54.6-5.35.1-5.14.54.0
Weight adjusted by age1.01.12.6-0.7-0.6-1.11.1-0.70.9-0.71.61.4
Bone surface0.20.31.1-0.1-0.20.2-0.1-0.50.4-0.60.71.1
Bone volume0.20.41.70.2-0.00.5-0.4-0.40.3-0.50.81.3
Breakpoint value in progressive ratio session0.20.20.4-0.2-0.3-0.60.60.40.10.50.50.0
Number of licking bursts0.20.21.00.20.0-0.10.1-0.10.4-0.10.81.0
Context. condit. distance diff. score0.50.61.1-0.9-0.6-1.11.0-0.40.5-0.4-0.5-0.9
Locomotion velocity, session 10.80.91.1-0.9-0.9-1.00.9-1.10.7-1.01.00.9
Locomotion distance, session 13.64.65.5-2.2-2.2-2.02.1-2.22.1-2.22.32.0
Locomotion velocity, session 20.10.10.2-0.4-0.4-0.20.2-0.30.1-0.20.1-0.1
Locomotion distance, session 20.81.12.5-0.8-1.0-0.60.8-0.91.0-0.91.61.5
Locomotion velocity, session 30.30.30.80.20.30.6-0.40.6-0.60.7-0.7-0.9
Locomotion distance, session 30.10.10.3-0.5-0.5-0.30.4-0.30.3-0.30.40.2
Stereotopy head waving bouts, day 33.13.64.32.02.12.1-2.01.8-1.91.9-1.9-1.4
Stereotopy head waving duration, day 30.20.20.40.50.50.6-0.60.3-0.40.3-0.6-0.3
Locomotion velocity, session 71.92.12.8-1.3-1.3-1.61.6-1.31.5-1.31.71.3
Locomotion distance, session 70.60.81.7-0.7-0.7-1.31.2-0.80.9-0.80.90.6
Stereotopy head waving bouts, day 70.30.40.90.80.71.0-0.80.5-0.50.5-0.3-0.1
Stereotopy head waving duration, day 70.20.30.70.50.50.8-0.70.4-0.40.4-0.3-0.1
Locomotion velocity, session 85.97.19.8-3.1-3.1-3.03.0-2.72.8-2.71.91.1
Locomotion distance, session 81.42.02.5-1.5-1.5-1.51.6-1.41.5-1.41.30.9
Degree of sensitization distance1.11.12.1-1.0-0.9-1.51.3-1.01.0-1.10.70.4
Degree of sensitization stereotypy0.40.40.90.90.80.9-0.80.6-0.50.6-0.10.1
Conditioned locomotion0.40.40.90.50.50.4-0.40.7-0.70.7-0.7-0.9
Cocaine response after cond. corrected0.30.31.20.70.40.2-0.3-0.00.10.00.81.1
Cocaine response after cond. not corrected0.30.31.20.90.50.1-0.20.10.10.10.81.1
Cocaine response before conditioning0.10.20.30.50.5-0.0-0.00.5-0.40.4-0.3-0.5
Saline control response0.71.01.7-0.5-0.7-1.11.0-0.91.0-0.91.31.2
Bone: connectivity density2.74.26.22.32.32.5-2.42.1-2.12.0-1.5-0.9
Bone: cortical apparent density7.39.711.63.33.42.8-2.93.3-3.43.2-3.0-2.6
Bone: cortical area0.00.00.10.30.20.0-0.00.20.00.20.00.0
Bone: cortical porosity0.20.20.90.2-0.10.1-0.1-0.30.3-0.10.61.0
Bone: cortical porosity0.40.41.70.0-0.3-0.30.2-0.60.5-0.41.01.3
Bone: cortical thickness1.11.82.61.61.50.9-0.91.6-1.21.6-1.2-1.2
Bone: cortical thickness5.76.78.92.82.82.4-2.43.0-2.72.7-2.3-2.0
Bone: cortical tissue density7.49.711.83.33.42.8-2.93.3-3.43.2-3.0-2.6
Condit. Reinf. active minus inactive responses1.61.82.41.21.21.1-1.11.6-1.51.5-1.4-1.5
Condit. Reinf. active-inactive response ratio2.72.94.51.41.61.4-1.31.8-1.81.8-1.9-2.1
Condit. Reinf. active responses1.21.52.11.31.21.0-0.91.5-1.31.4-1.1-1.3
Condit. Reinf. inactive responses0.10.10.30.30.1-0.20.10.10.2-0.00.40.5
Incentive salience index mean2.22.73.31.71.61.6-1.61.8-1.81.7-1.4-1.3
Condit. Reinf. lever presses0.60.81.41.21.00.9-0.91.0-0.90.9-0.5-0.3
Condit. Reinf. active minus inactive responses0.70.81.21.10.91.1-1.11.1-0.90.9-0.4-0.1
Condit. Reinf. active-inactive response ratio0.50.51.20.80.61.1-1.00.7-0.60.5-0.10.3
Condit. Reinf. active responses0.91.32.01.41.21.4-1.41.2-1.11.1-0.30.2
Condit. Reinf. inactive responses1.01.22.11.51.41.2-1.31.2-1.11.1-0.30.2
Condit. Reinf. lever presses0.20.20.40.40.40.4-0.40.6-0.50.7-0.4-0.3
Condit. Reinf. lever reinforcers received1.11.62.21.51.31.5-1.51.4-1.31.4-0.5-0.1
Conditioned reinforcement - actives0.50.51.01.00.90.2-0.31.0-0.61.0-0.4-0.2
Conditioned reinforcement - inactives2.32.63.41.71.71.6-1.71.5-1.91.7-1.7-1.2
Conditioned locomotion0.30.30.60.80.80.2-0.20.8-0.50.80.20.0
Patch foraging indifference point 0 sec2.84.55.32.02.22.2-2.12.1-2.32.2-2.1-1.8
Patch foraging indifference point AUC0.10.10.3-0.2-0.2-0.60.5-0.20.3-0.40.30.3
Delay disc. indifference point, 0s delay0.80.91.41.21.11.0-0.91.2-0.70.9-0.6-0.6
Delay disc. indifference point, 16s delay1.21.22.70.91.00.8-0.91.0-1.20.7-1.6-1.5
Delay disc. indifference point, 2s delay0.30.41.01.00.90.5-0.40.7-0.00.50.30.4
Delay disc. indifference point, 24s delay0.10.10.40.00.10.2-0.20.1-0.3-0.0-0.6-0.5
Delay disc. indifference point, 4s delay0.40.41.00.90.70.4-0.41.0-0.20.8-0.2-0.2
Delay disc. indifference point, 8s delay0.10.10.20.40.40.4-0.30.3-0.20.2-0.3-0.5
Indifference point function ln k0.30.41.20.20.30.4-0.30.5-0.40.6-0.9-1.1
Indifference point function log k0.30.41.20.20.30.4-0.30.5-0.40.6-0.9-1.1
Patch foraging total patch changes 0 sec2.13.44.21.71.91.9-1.81.8-2.01.8-1.9-1.7
Patch foraging total patch changes 12 sec3.74.87.22.72.72.4-2.32.4-2.22.2-1.3-0.7
Patch foraging total patch changes 18 sec0.50.71.00.91.00.8-0.80.9-1.00.9-0.7-0.5
Patch foraging total patch changes 24 sec1.11.42.31.51.50.9-0.91.4-1.11.3-0.8-0.9
Patch foraging total patch changes 6 sec2.33.44.31.92.02.1-2.11.8-2.11.8-1.6-1.0
Patch foraging time to switch 0 sec0.00.10.10.30.30.3-0.30.1-0.30.20.10.1
Patch foraging water rate 0 sec0.10.20.40.20.10.5-0.50.5-0.40.4-0.6-0.4
Patch foraging water rate 12 sec0.10.10.2-0.2-0.3-0.50.50.10.20.30.0-0.4
Patch foraging water rate 18 sec0.20.20.50.70.40.7-0.60.5-0.30.50.00.1
Patch foraging water rate 24 sec0.60.81.50.90.71.2-1.20.9-0.80.8-0.8-0.3
Patch foraging water rate 6 sec1.42.02.81.51.41.5-1.61.7-1.31.6-1.1-0.8
Seeking ratio, delayed vs. immediate footshock1.01.12.30.80.90.1-0.31.3-1.01.2-1.5-1.5
Distance traveled before self-admin0.20.21.2-0.3-0.4-0.10.0-0.30.0-0.20.51.1
Distance traveled after self-admin1.11.22.0-1.4-1.3-0.80.8-1.40.9-1.30.91.0
Extensor digitorum longus weight7.328.838.6-6.2-6.0-6.16.1-5.65.4-5.63.72.1
Bone: elastic displacement0.00.00.00.1-0.00.00.10.1-0.00.1-0.2-0.1
Bone: elastic work0.00.00.20.10.00.1-0.00.10.10.10.30.5
Bone: endosteal estimation3.06.69.0-2.6-2.7-2.02.0-3.02.5-3.02.62.7
Bone: endosteal perimeter1.43.04.1-1.9-1.9-1.51.4-2.01.7-2.01.51.5
Epididymis fat weight0.20.41.0-0.6-0.7-0.60.6-0.40.6-0.40.81.0
Delta time in closed arm before/after self-admin4.14.04.9-2.1-2.1-2.12.2-2.02.2-2.21.71.0
Delta time in open arm before/after self-admin0.00.00.10.1-0.00.1-0.2-0.0-0.20.1-0.30.1
Diff in mean of infusions in LGA sessions0.20.30.7-0.3-0.4-0.70.80.20.50.20.70.1
Delay discount exponential model param0.10.10.3-0.4-0.4-0.30.2-0.50.1-0.30.30.4
Extinction: sum of active levers before priming2.22.22.8-1.5-1.4-1.51.5-1.71.5-1.51.41.1
Active lever presses in extinction session 60.60.62.00.60.40.6-0.60.3-0.50.41.11.4
Bone: final force0.20.41.50.60.50.5-0.50.00.0-0.00.71.2
Bone: final moment0.20.41.90.40.30.3-0.3-0.20.2-0.20.91.4
Food consumed during 24 hour testing period0.70.91.3-1.1-1.0-0.80.8-1.01.1-1.00.70.7
Glucose0.10.10.30.30.2-0.40.2-0.10.1-0.20.40.6
Heart weight3.24.55.6-2.3-2.3-2.32.4-2.31.9-2.31.61.3
Delay discount hyperbolic model param0.20.20.4-0.5-0.5-0.30.3-0.60.1-0.40.30.4
Intermittent access intake day 1-15 change0.50.50.90.70.50.7-0.60.9-0.31.0-0.6-0.8
Intermittent access intake escalation0.40.40.90.70.50.6-0.50.9-0.21.0-0.5-0.7
Intermittent access intake escalation 20.00.00.2-0.0-0.20.1-0.00.10.40.10.1-0.1
Intermitt. access day 1 inactive lever presses2.02.23.81.41.42.0-1.81.5-1.51.5-1.1-1.0
Intermitt. access day 15 inactive lever presses4.75.26.42.42.32.5-2.42.5-2.22.5-1.9-1.7
Intermitt. access escalation Index1.91.72.4-1.4-1.3-1.21.3-1.51.4-1.61.10.7
Intermittent access day 1 total infusions0.10.20.40.40.60.2-0.30.4-0.60.4-0.10.5
Intermittent access day 15 total infusions0.60.61.00.90.90.7-0.71.0-0.71.0-0.8-0.6
Intermittent access terminal intake (last 3 days)0.70.70.90.90.90.9-0.90.9-0.81.0-0.8-0.4
Intermittent access total infusions0.20.20.30.50.50.3-0.40.5-0.50.6-0.40.1
Intermittent access day 1 locomotion0.30.30.80.60.70.4-0.50.5-0.90.5-0.50.0
Intermittent access day 15 total locomotion0.20.30.50.70.70.4-0.40.6-0.60.5-0.30.0
Intermittent access total locomotion0.91.01.31.11.10.9-0.91.2-1.11.1-0.9-0.6
Intermittent access standard deviation2.42.63.61.51.51.6-1.51.9-1.41.9-1.5-1.6
Left kidney weight0.51.33.2-1.8-1.6-1.01.0-1.40.9-1.10.4-0.0
Right kidney weight0.20.71.1-0.9-0.8-0.50.6-0.90.6-0.91.00.9
Cocaine induced anxiety2.93.44.6-1.9-2.0-1.31.4-1.92.0-1.92.21.7
Post-drug Anxiety0.50.50.9-0.6-0.6-0.50.5-0.70.8-0.71.00.9
Baseline Anxiety1.92.02.81.71.71.0-1.11.5-1.41.5-1.5-1.2
Tail length0.10.20.6-0.8-0.7-0.50.5-0.10.3-0.2-0.1-0.4
Length with tail2.17.711.7-3.4-3.4-2.93.0-2.72.8-2.62.11.3
Length without tail4.39.511.9-3.3-3.4-3.13.1-3.13.1-2.93.02.5
Times rat made contact with spout0.50.61.30.90.91.1-1.10.5-0.60.6-0.30.4
Lifetime Intake0.30.30.50.50.60.5-0.50.7-0.60.7-0.5-0.1
Liver weight, left0.00.00.10.10.1-0.20.20.3-0.10.30.2-0.0
Liver weight, right0.40.60.90.80.90.9-0.90.8-1.00.8-0.5-0.4
Locomotor activity0.20.30.80.70.40.4-0.40.4-0.10.40.60.9
Locomotor testing distance1.52.53.71.91.81.8-1.71.8-1.51.8-0.9-0.4
Locomotor testing rearing7.711.914.23.53.63.7-3.73.5-3.83.4-3.2-2.5
Locomotion in novel chamber3.74.57.82.82.71.9-2.02.3-2.22.4-1.3-0.5
Locomotion in novel chamber post-restriction0.40.40.80.80.40.9-0.70.5-0.30.60.60.8
Fecal boli incidents, locomotor time 10.30.40.6-0.6-0.6-0.60.5-0.70.4-0.70.60.7
Change in fecal boli incidents, locomotor task0.10.10.2-0.0-0.0-0.40.4-0.10.3-0.10.2-0.0
Time >=10cm from walls, locomotor time 10.50.51.00.70.80.1-0.20.7-0.60.8-0.8-1.0
Bouts of movement, locomotor time 10.30.40.8-0.9-0.8-0.30.4-0.70.3-0.60.60.6
Total resting periods, locomotor time 11.11.21.8-1.3-1.2-0.80.9-1.20.7-1.21.11.1
Rest time, locomotor task time 10.10.10.3-0.10.00.6-0.5-0.3-0.5-0.20.10.5
Distance moved, locomotor task time 10.10.10.10.40.2-0.40.20.20.40.2-0.1-0.2
Vertical activity count, locomotor time 10.70.81.9-0.3-0.5-1.31.3-0.31.4-0.30.80.5
Time >=10cm from walls, locomotor time 20.60.61.61.21.3-0.0-0.21.0-0.51.1-0.1-0.1
Bouts of movement, locomotor time 20.90.91.70.50.70.9-0.90.8-1.30.9-1.2-1.1
Total resting periods, locomotor time 20.80.81.60.40.60.8-0.80.8-1.30.8-1.2-1.2
Rest time, locomotor task time 20.60.71.2-1.1-1.0-0.80.9-0.90.6-0.90.80.6
Distance moved, locomotor task time 20.30.40.8-0.2-0.4-0.80.7-0.70.9-0.60.60.5
Vertical activity count, locomotor time 20.60.71.7-0.5-0.6-1.21.1-0.71.3-0.50.70.4
Light reinforcement 12.85.17.32.32.42.7-2.62.4-2.32.2-1.8-1.2
Light reinforcement 20.20.30.70.60.60.9-0.80.2-0.3-0.10.20.7
Bone: marrow area2.86.28.5-2.5-2.6-1.91.9-2.92.4-2.92.52.6
Bone: maximum diameter0.00.00.20.1-0.00.1-0.1-0.00.1-0.10.30.5
Bone: maximum force0.30.61.7-0.4-0.4-0.30.3-0.80.7-0.81.01.3
Bone: maximum moment0.40.71.8-0.5-0.6-0.40.5-1.00.9-0.91.11.3
Mean time between licks in bursts1.01.52.1-1.4-1.4-1.01.0-1.41.2-1.40.91.0
Mean num. licks in bursts0.40.50.90.50.60.8-0.80.5-0.80.5-0.9-0.7
Cd content in liver0.20.20.50.30.30.7-0.60.3-0.40.3-0.3-0.2
Co content in liver0.20.30.5-0.7-0.7-0.50.5-0.50.3-0.6-0.0-0.3
Cu content in liver0.20.30.90.00.20.3-0.30.5-0.60.5-0.8-0.9
Fe content in liver1.31.62.0-1.3-1.4-1.11.2-1.21.4-1.31.31.1
K content in liver1.21.21.71.21.21.1-1.21.3-1.11.3-0.8-0.6
Mg content in liver2.92.94.31.41.61.3-1.41.9-1.61.9-2.0-2.1
Mn content in liver3.53.94.71.82.02.0-2.02.2-2.02.2-2.0-1.8
Na content in liver0.30.31.40.20.00.1-0.1-0.20.2-0.10.91.2
Rb content in liver1.72.22.61.51.61.6-1.61.4-1.51.4-1.4-1.0
Se content in liver6.07.48.72.82.72.8-2.92.9-2.92.8-2.4-1.8
Sr content in liver0.60.51.10.40.60.4-0.40.8-0.80.8-0.9-1.1
Zn content in liver3.23.55.12.01.92.3-2.31.8-1.91.8-1.6-0.9
Bone: minimum diameter0.81.41.7-1.1-1.2-1.11.1-1.31.2-1.21.21.2
Time in familiar zone, hab. session 10.60.63.00.1-0.20.2-0.2-0.50.4-0.71.01.7
Time in novel zone, hab. session 12.32.24.71.11.31.1-1.01.5-1.41.6-1.9-2.2
Total zone transitions, hab. session 11.21.72.5-1.6-1.5-1.51.5-1.41.2-1.40.80.4
Total locomotion distance, hab. session 10.00.10.30.00.00.00.10.2-0.00.2-0.3-0.5
Locomotion velocity, hab. session 10.10.20.4-0.6-0.5-0.60.6-0.30.4-0.30.2-0.2
Time in familiar zone, hab. session 20.20.20.40.60.40.6-0.70.3-0.20.20.00.6
Time in novel zone, hab. session 20.60.61.10.50.70.6-0.60.7-0.90.8-0.9-1.1
Total zone transitions, hab. session 21.31.62.1-1.2-1.2-1.51.5-1.31.3-1.31.20.9
Total locomotion distance, hab. session 20.70.91.3-0.7-0.8-0.80.9-0.91.0-0.91.21.0
Locomotion velocity, hab. session 20.91.21.7-0.9-1.1-1.11.2-1.11.3-1.11.31.1
Novel to familiar place preference ratio0.40.40.8-0.9-0.7-0.80.8-0.40.4-0.4-0.1-0.5
Novelty place preference0.30.30.8-0.7-0.4-0.70.6-0.20.2-0.2-0.4-0.9
Time in novel zone, NPP test0.20.20.9-0.3-0.0-0.30.20.1-0.10.1-0.6-1.0
Total zone transitions, NPP test1.52.12.9-1.1-1.1-1.31.3-1.51.4-1.71.71.7
Total locomotion distance, NPP test0.40.51.3-0.3-0.4-0.30.4-0.80.7-0.81.01.1
Locomotion velocity, NPP test0.81.21.6-0.9-0.9-0.91.0-1.21.1-1.21.21.2
Intraocular pressure2.33.24.2-1.9-2.0-1.91.9-1.91.6-2.01.51.0
Delta distance traveled before/after self-admin0.90.91.5-1.2-1.1-1.01.1-1.10.9-1.10.5-0.1
Delta ambulatory time before/after self-admin0.80.91.5-1.2-1.0-0.70.8-1.20.9-1.20.70.2
Parametrial fat weight1.02.04.11.51.32.0-1.91.4-1.31.4-0.50.0
Pavlov. Cond. lever latency1.11.42.7-1.6-1.3-1.51.5-1.01.1-0.90.0-0.7
Pavlov. Cond. magazine entry latency6.68.512.83.63.33.4-3.42.9-3.12.8-1.7-0.6
Pavlov. Cond. change in total contacts9.310.012.03.43.33.4-3.53.2-3.43.1-2.8-2.0
Pavlov. Cond. index score4.55.89.63.12.82.9-2.92.3-2.52.2-1.1-0.1
Pavlov. Cond. latency score3.03.96.82.62.32.4-2.41.8-2.01.7-0.70.3
Pavlov. Cond. lever contacts0.81.01.91.41.01.3-1.30.8-0.80.70.20.8
Pavlov. Cond. magazine entry number9.011.216.2-4.0-3.8-3.93.9-3.33.5-3.22.21.1
Pavlov. Cond. intertrial magazine entries0.70.91.6-1.2-1.1-1.31.3-0.80.8-0.80.2-0.3
Pavlov. Cond. lever-magazine prob. diff.5.56.911.03.33.03.1-3.12.6-2.72.5-1.4-0.4
Pavlov. Cond. response bias6.78.211.83.43.23.3-3.32.9-3.02.8-1.9-1.0
Pavlov. Cond. lever latency0.20.30.5-0.6-0.5-0.60.6-0.60.4-0.70.2-0.2
Pavlov. Cond. magazine entry latency0.30.40.7-0.3-0.4-0.80.8-0.20.8-0.40.80.7
Pavlov. Cond. change in total contacts0.81.01.51.11.20.9-0.91.2-1.01.2-0.9-0.6
Pavlov. Cond. index score0.10.10.30.40.20.2-0.20.30.10.20.20.5
Pavlov. Cond. latency score0.00.10.30.20.10.0-0.00.10.20.10.30.6
Pavlov. Cond. lever contacts0.30.40.80.90.70.8-0.80.7-0.40.70.00.5
Pavlov. Cond. magazine entry number0.10.10.2-0.10.10.3-0.3-0.1-0.4-0.0-0.4-0.4
Pavlov. Cond. intertrial magazine entries0.40.61.1-1.1-0.7-1.01.0-0.40.3-0.5-0.3-1.0
Pavlov. Cond. lever-magazine prob. diff.0.00.10.30.20.00.0-0.00.20.20.10.30.5
Pavlov. Cond. response bias0.50.61.21.10.90.8-0.91.0-0.50.9-0.10.4
Time in closed arm before self-admin2.83.25.11.41.52.1-2.11.3-2.11.4-2.3-1.7
Time in closed arm after self-admin0.30.31.5-0.4-0.1-0.00.1-0.1-0.1-0.2-1.0-1.2
Time in open arm before self-admin2.83.15.2-1.6-1.6-2.32.3-1.31.9-1.41.91.2
Time in open arm after self-admin0.70.71.1-0.7-0.9-1.01.0-0.60.9-0.80.90.8
Bone: periosteal estimation0.71.32.4-1.0-1.1-0.80.7-1.31.1-1.31.31.5
Bone: periosteal perimeter1.32.12.7-1.3-1.5-1.11.1-1.61.6-1.61.51.6
Bone: post-yield work1.31.82.4-1.5-1.5-1.31.3-1.51.5-1.41.10.8
Progressive ratio test 1 active lever presses0.80.81.50.91.11.0-1.10.7-1.20.7-0.9-0.2
Progressive ratio test 1 breakpoint0.70.71.30.81.00.9-1.00.6-1.10.7-0.8-0.1
Progressive ratio test 1 inactive lever presses2.32.53.51.41.51.9-1.81.5-1.71.6-1.6-1.2
Progressive ratio test 2 active lever presses1.51.62.01.41.41.2-1.31.3-1.41.4-1.2-0.5
Progressive ratio test 2 breakpoint1.11.21.61.21.21.1-1.21.1-1.31.2-1.0-0.4
Progressive ratio test 2 inactive lever presses0.60.70.90.90.90.8-0.80.8-1.00.9-0.7-0.4
Incentive Sensitization - Responses1.31.31.81.31.21.1-1.31.2-1.21.2-0.9-0.3
Incentive Sensitization - Breakpoint1.21.21.71.31.21.1-1.31.1-1.21.2-0.8-0.2
Sum of active levers in priming session hrs 5-60.10.10.30.50.40.3-0.30.3-0.60.20.10.2
Progressive ratio0.10.10.50.20.1-0.30.20.20.30.10.60.7
Food seeking constrained by brief footshock0.20.20.70.40.30.8-0.80.2-0.30.2-0.00.2
Seeking ratio, punishment vs. effort0.10.20.30.10.20.6-0.5-0.1-0.4-0.1-0.5-0.5
Retroperitoneal fat weight0.10.20.6-0.5-0.50.1-0.2-0.70.2-0.60.20.8
Reaction time number correct1.52.13.3-1.2-1.3-1.81.8-1.21.6-1.11.71.2
Reaction time mean minus median0.30.40.7-0.6-0.5-0.70.8-0.40.8-0.50.60.0
Reaction time mean minus median AUC0.00.10.2-0.00.0-0.20.30.00.5-0.20.3-0.1
Reaction time num false alarms0.20.20.80.60.50.5-0.50.20.20.00.40.9
Reaction time num false alarms AUC0.20.20.90.50.30.3-0.30.10.4-0.00.60.9
Reaction time trials correct on left1.52.13.3-1.2-1.3-1.81.8-1.21.6-1.11.71.2
Reaction time trials on left1.42.13.2-1.1-1.3-1.81.7-1.21.6-1.11.61.2
Reaction time mean0.70.91.90.70.70.9-0.71.1-0.91.1-1.0-1.4
Reaction time mean AUC0.70.92.00.70.70.9-0.71.1-0.91.1-1.0-1.4
Median of all reaction times1.82.53.01.41.31.6-1.51.7-1.61.7-1.6-1.7
Reaction time omissions0.71.01.61.21.21.3-1.11.1-1.00.9-0.5-0.4
Reaction time false alarm rate0.50.61.41.00.91.2-1.20.7-0.40.5-0.30.2
Reaction time premature initiation rate0.20.20.70.60.50.4-0.30.8-0.20.80.1-0.0
Reaction time premature initiations0.30.41.1-0.3-0.4-0.70.8-0.10.80.01.00.6
Std. dev. reaction times0.00.00.10.0-0.0-0.10.20.20.20.10.2-0.3
Reaction time trials completed1.42.13.2-1.1-1.3-1.81.7-1.21.6-1.11.61.2
Reaction time trials AUC1.31.83.1-1.0-1.1-1.81.7-1.11.5-1.01.51.0
Run reversals in cocaine runway, females1.41.42.8-1.3-1.4-1.71.6-1.11.1-0.7-0.0-0.6
Run reversals in cocaine runway, males0.40.40.60.80.70.8-0.80.6-0.50.6-0.5-0.2
Latency to leave start box in cocaine runway1.21.31.9-1.3-1.3-1.41.3-1.21.0-1.20.60.6
Latency to leave start box in cocaine runway, F1.71.82.7-1.4-1.4-1.61.5-1.31.3-1.31.11.1
Latency to leave start box in cocaine runway, M0.80.81.80.50.50.9-0.90.7-1.00.7-1.3-1.2
Std. dev. time between licks in bursts0.10.10.3-0.4-0.4-0.10.1-0.40.4-0.40.40.6
Total sessions with >9 infusions1.01.11.61.01.11.0-1.01.0-1.01.0-1.3-1.1
Short access day 1 total inactive lever presses2.02.32.91.71.71.6-1.51.6-1.61.6-1.2-0.8
Short access day 10 total inactive lever presses0.10.10.3-0.4-0.5-0.00.2-0.20.6-0.10.2-0.3
Short access day 1 total infusions1.31.42.01.01.01.3-1.31.1-1.31.1-1.4-0.9
Short access day 10 total infusions0.20.30.50.60.70.4-0.40.5-0.60.5-0.10.4
Short access total infusions0.50.60.80.60.70.7-0.70.9-0.80.9-0.9-0.6
Short access day 1 locomotion4.14.45.72.22.22.4-2.32.2-2.12.1-1.9-1.4
Short access day 10 total locomotion1.31.42.11.31.41.4-1.41.2-1.31.1-0.8-0.3
Short access total locomotion1.01.01.60.91.01.0-1.01.0-1.10.9-1.3-1.0
One hour access (0.3 mA shock)0.00.00.10.10.1-0.20.20.2-0.10.3-0.20.0
Compulsive drug intake0.30.31.4-0.2-0.3-0.30.3-0.10.4-0.1-1.0-1.2
One hour access (shock baseline)0.20.20.30.50.50.2-0.30.4-0.50.50.20.6
Social response proportion0.40.40.8-0.6-0.6-0.60.6-0.90.4-0.80.40.6
Social responses0.20.20.9-0.0-0.30.3-0.3-0.40.2-0.50.41.0
Social time0.91.22.9-0.6-0.9-0.50.6-1.10.9-1.01.61.7
Soleus weight0.51.44.0-0.4-0.6-0.50.6-1.31.1-1.21.72.0
Bone: stiffness0.10.20.7-0.2-0.1-0.20.1-0.50.4-0.50.60.8
Tibialis anterior weight1.75.97.4-2.5-2.6-2.42.4-2.72.5-2.72.21.9
Time to tail flick, vehicle, before self-admin0.00.00.10.10.00.4-0.3-0.1-0.1-0.00.00.2
Time to tail flick, vehicle, after self-admin0.10.10.50.1-0.1-0.00.0-0.00.3-0.10.60.7
Time to tail flick, test, before self-admin1.51.52.6-1.3-1.3-1.21.4-1.01.6-1.11.20.5
Time to tail flick, test, after self-admin0.20.20.90.10.10.3-0.3-0.2-0.4-0.40.40.9
Delta time to tail flick, vehicle, before/after SA0.30.31.20.1-0.00.1-0.0-0.00.4-0.21.01.1
Delta time to tail flick, test, before/after SA1.91.73.31.61.51.3-1.51.1-1.81.0-1.0-0.0
Tibia length2.88.09.1-2.6-2.7-2.62.6-3.03.0-3.02.92.9
Ambulatory time before self-admin0.10.10.3-0.3-0.4-0.20.1-0.20.0-0.10.20.5
Ambulatory time after self-admin2.02.23.7-1.9-1.9-0.91.0-1.91.2-1.71.31.2
Bone: tissue strength0.80.81.1-1.0-1.0-1.01.0-1.01.1-0.80.70.5
Total heroin consumption0.80.91.31.10.91.2-1.11.0-1.01.00.50.9
Bone: trabecular number3.35.18.12.82.62.8-2.82.2-2.22.1-1.2-0.3
Bone: trabecular spacing2.93.74.3-1.7-1.8-1.91.8-2.12.0-2.12.01.9
Bone: trabecular thickness0.10.10.40.40.20.6-0.50.3-0.30.2-0.3-0.1
Bone: trabecular tissue density0.81.13.60.40.70.4-0.40.9-1.00.9-1.6-1.9
Water consumed over 24 hours0.10.20.3-0.3-0.3-0.30.3-0.50.6-0.40.50.5
Number of responses in last shaping day1.01.11.70.80.80.9-0.91.0-1.01.0-1.3-1.3