Hub : Genes

Gk5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Gk5 0.06 0.04 6.3e-05 0.02 0.03 0.02 0.03 2.2e-03 7.4e-04 1.2e-02 6.8e-04
2 pVTA gene expression Gk5 0.19 0.09 1.3e-07 0.14 0.14 0.12 0.14 1.1e-06 1.8e-06 7.3e-06 1.9e-06
3 Liver gene expression Gk5 0.07 0.04 9.0e-09 0.04 0.06 0.05 0.05 1.4e-05 1.9e-07 1.8e-06 5.2e-06
4 LHb gene expression Gk5 0.16 0.11 8.3e-03 0.07 0.01 0.02 0.05 8.5e-03 2.0e-01 1.1e-01 2.6e-02
5 NAcc gene expression Gk5 0.1 0.06 3.1e-09 0.07 0.08 0.07 0.08 6.0e-09 4.1e-09 6.8e-09 1.6e-09
6 Brain gene expression Gk5 0.12 0.06 4.1e-14 0.17 0.15 0.14 0.15 2.1e-15 8.0e-14 1.4e-12 4.7e-14
7 BLA gene expression Gk5 0.47 0.16 5.6e-10 0.16 0.16 0.21 0.21 7.7e-09 3.8e-09 1.9e-11 2.3e-11
8 PL gene expression Gk5 0.4 0.14 4.4e-15 0.14 0.14 0.13 0.14 1.0e-14 2.2e-15 3.4e-14 7.9e-15
9 NAcc alternative TSS XM_008766574.3 0.02 0.02 6.2e-03 0.01 0.01 0.01 0.01 9.1e-03 9.7e-03 7.4e-03 1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.50.91.3-1.10.71.00.9-1.00.81.1-1.00.6
Area under the delay curve0.60.61.7-0.90.61.30.6-0.50.40.9-0.60.9
BMI with tail5.919.226.05.1-4.7-5.0-4.04.5-4.5-4.04.5-2.6
BMI without tail2.75.515.53.2-1.9-3.9-2.12.0-1.9-2.21.9-0.3
Body weight4.117.227.15.2-4.2-4.8-3.94.3-4.2-3.74.2-2.0
Weight adjusted by age2.63.06.21.5-1.5-1.9-1.02.1-1.6-2.52.0-1.0
Bone surface1.12.04.2-1.71.22.00.9-1.31.11.5-1.51.2
Bone volume0.61.11.8-1.20.91.40.8-1.00.81.2-1.20.7
Breakpoint value in progressive ratio session0.60.71.1-1.00.81.00.8-0.90.90.7-0.70.6
Number of licking bursts0.40.41.5-0.30.40.90.3-0.50.50.7-0.41.2
Context. condit. distance diff. score0.50.62.00.2-0.70.7-0.80.7-0.8-0.60.6-1.4
Locomotion velocity, session 12.12.33.31.8-1.6-1.6-1.41.4-1.4-1.51.4-1.3
Locomotion distance, session 14.86.18.32.9-2.8-2.3-2.52.4-2.4-2.42.3-2.3
Locomotion velocity, session 25.86.89.13.0-2.8-1.8-2.72.8-2.8-2.62.4-2.4
Locomotion distance, session 26.18.611.43.4-3.2-2.4-3.03.2-3.1-3.02.6-2.3
Locomotion velocity, session 31.01.11.60.6-1.21.2-1.11.2-1.2-1.01.10.7
Locomotion distance, session 30.20.20.70.1-0.40.8-0.70.5-0.6-0.3-0.0-0.1
Stereotopy head waving bouts, day 30.80.95.0-0.40.11.40.20.2-0.0-0.30.82.2
Stereotopy head waving duration, day 30.70.82.80.3-0.30.3-0.20.8-0.5-1.01.61.7
Locomotion velocity, session 73.84.15.82.1-2.0-1.8-1.92.3-2.1-2.42.1-1.7
Locomotion distance, session 70.50.62.00.9-0.4-1.4-0.60.6-0.5-0.70.1-1.1
Stereotopy head waving bouts, day 71.31.57.6-1.70.32.80.5-0.20.4-0.30.61.3
Stereotopy head waving duration, day 71.61.97.9-1.90.72.80.8-0.50.80.10.32.0
Locomotion velocity, session 83.03.65.11.8-2.2-0.8-2.22.0-2.0-2.11.9-1.8
Locomotion distance, session 82.94.25.51.9-2.3-0.7-2.32.2-2.2-2.11.8-2.3
Degree of sensitization distance0.60.63.60.8-0.0-1.90.2-0.00.0-0.20.2-1.0
Degree of sensitization stereotypy0.90.94.8-0.9-0.52.2-0.40.5-0.4-0.91.0-0.2
Conditioned locomotion0.50.61.3-0.71.1-0.70.8-0.81.00.2-0.9-0.4
Cocaine response after cond. corrected0.10.20.60.5-0.3-0.5-0.50.10.0-0.20.20.8
Cocaine response after cond. not corrected0.30.30.80.8-0.2-0.8-0.6-0.20.20.3-0.10.9
Cocaine response before conditioning0.10.10.30.30.1-0.5-0.1-0.30.30.4-0.20.5
Saline control response2.33.04.12.0-1.8-1.6-1.51.8-1.6-1.91.8-1.3
Bone: connectivity density0.81.22.2-1.51.01.21.1-1.11.10.9-1.00.5
Bone: cortical apparent density0.10.10.4-0.00.1-0.6-0.0-0.40.50.0-0.1-0.4
Bone: cortical area3.04.66.21.8-2.5-0.4-2.52.4-2.5-2.12.5-1.8
Bone: cortical porosity1.31.43.90.9-1.3-0.3-1.11.2-1.5-0.71.0-2.0
Bone: cortical porosity1.61.75.20.9-1.4-0.3-1.11.3-1.6-0.91.2-2.3
Bone: cortical thickness1.52.43.51.3-1.7-0.2-1.81.7-1.9-1.61.8-1.1
Bone: cortical thickness0.10.10.50.2-0.3-0.4-0.20.1-0.60.40.1-0.7
Bone: cortical tissue density0.10.10.4-0.00.1-0.6-0.0-0.40.40.0-0.1-0.4
Condit. Reinf. active minus inactive responses0.10.10.40.4-0.40.0-0.2-0.1-0.40.60.10.2
Condit. Reinf. active-inactive response ratio2.12.33.92.0-1.9-1.3-1.61.3-1.8-0.71.6-1.1
Condit. Reinf. active responses0.10.10.4-0.10.00.30.2-0.3-0.00.6-0.30.5
Condit. Reinf. inactive responses1.92.22.9-1.71.61.21.5-1.41.51.3-1.71.5
Incentive salience index mean0.50.71.51.0-1.2-0.1-0.90.8-1.2-0.10.7-0.4
Condit. Reinf. lever presses2.12.84.01.8-2.0-0.8-1.81.9-2.0-1.51.6-1.1
Condit. Reinf. active minus inactive responses0.40.52.1-0.40.20.40.4-0.60.41.2-0.51.5
Condit. Reinf. active-inactive response ratio0.50.52.40.7-0.4-0.7-0.4-0.1-0.10.70.11.6
Condit. Reinf. active responses0.81.11.9-1.20.71.30.7-0.80.81.2-0.81.4
Condit. Reinf. inactive responses0.70.82.1-1.40.91.40.8-0.60.70.4-0.80.0
Condit. Reinf. lever presses0.40.62.0-0.3-0.21.2-0.1-0.40.11.2-0.41.4
Condit. Reinf. lever reinforcers received0.50.71.4-1.00.41.20.6-0.70.51.1-0.61.1
Conditioned reinforcement - actives0.10.10.30.00.30.00.1-0.30.30.3-0.50.3
Conditioned reinforcement - inactives0.00.00.20.20.10.0-0.40.10.1-0.4-0.20.1
Conditioned locomotion0.20.30.70.8-0.3-0.4-0.70.2-0.4-0.40.1-0.8
Patch foraging indifference point 0 sec0.10.10.40.30.2-0.6-0.4-0.20.10.2-0.1-0.1
Patch foraging indifference point AUC0.30.41.70.10.1-0.70.30.4-0.2-0.90.4-1.3
Delay disc. indifference point, 0s delay1.71.93.7-1.61.21.91.3-1.11.11.2-1.01.6
Delay disc. indifference point, 16s delay0.20.20.50.1-0.50.6-0.30.6-0.7-0.20.60.5
Delay disc. indifference point, 2s delay0.20.20.50.3-0.40.5-0.70.4-0.60.20.20.6
Delay disc. indifference point, 24s delay0.20.10.3-0.40.30.10.4-0.40.10.5-0.3-0.6
Delay disc. indifference point, 4s delay2.12.24.4-1.51.41.71.1-1.31.31.5-1.42.1
Delay disc. indifference point, 8s delay0.40.41.1-0.80.41.00.6-0.50.20.9-0.50.2
Indifference point function ln k0.20.31.80.00.10.30.0-0.40.20.7-0.11.3
Indifference point function log k0.20.31.80.00.10.30.0-0.40.20.7-0.11.3
Patch foraging total patch changes 0 sec0.10.20.50.5-0.3-0.6-0.70.2-0.3-0.10.3-0.2
Patch foraging total patch changes 12 sec1.31.75.60.8-0.9-1.0-0.41.3-1.2-1.71.1-2.4
Patch foraging total patch changes 18 sec0.20.20.90.20.0-1.00.20.0-0.10.2-0.1-0.9
Patch foraging total patch changes 24 sec0.10.10.5-0.10.2-0.20.7-0.30.10.4-0.1-0.2
Patch foraging total patch changes 6 sec0.10.10.2-0.20.3-0.40.00.10.1-0.40.1-0.4
Patch foraging time to switch 0 sec1.72.64.3-1.61.51.21.6-1.91.71.9-2.10.6
Patch foraging water rate 0 sec0.71.11.91.1-0.9-1.3-1.01.2-1.0-1.21.40.2
Patch foraging water rate 12 sec0.60.91.71.0-1.1-0.4-1.11.1-1.1-0.71.30.5
Patch foraging water rate 18 sec2.23.05.22.3-1.8-1.7-2.01.7-1.7-1.41.7-0.7
Patch foraging water rate 24 sec0.20.30.70.3-0.4-0.3-0.40.7-0.6-0.50.70.8
Patch foraging water rate 6 sec0.71.01.91.2-1.2-0.3-1.41.1-1.2-0.51.10.6
Seeking ratio, delayed vs. immediate footshock0.30.31.7-0.90.10.40.20.1-0.1-0.30.3-1.3
Distance traveled before self-admin2.02.23.71.9-1.5-1.5-1.71.4-1.4-1.21.1-1.3
Distance traveled after self-admin0.10.10.80.2-0.1-0.9-0.0-0.00.10.0-0.3-0.5
Extensor digitorum longus weight2.911.215.13.7-3.7-1.8-3.93.8-3.6-3.53.5-1.8
Bone: elastic displacement2.63.04.21.8-1.8-1.7-1.61.7-1.8-1.41.6-2.0
Bone: elastic work1.52.02.61.5-1.6-1.1-1.31.5-1.6-1.21.4-1.3
Bone: endosteal estimation0.51.11.81.0-1.3-0.3-1.11.3-1.2-1.21.0-0.6
Bone: endosteal perimeter2.04.25.91.9-2.4-0.7-2.42.3-2.2-2.22.1-1.8
Epididymis fat weight0.92.03.61.6-1.2-1.9-1.11.5-1.4-1.51.5-1.0
Delta time in closed arm before/after self-admin0.70.72.2-0.3-0.71.5-0.30.9-0.6-0.90.7-1.0
Delta time in open arm before/after self-admin0.40.40.9-0.20.9-0.50.6-0.50.9-0.2-0.7-0.3
Diff in mean of infusions in LGA sessions0.40.41.6-0.80.41.30.4-0.40.40.3-0.10.9
Delay discount exponential model param0.60.61.10.9-0.7-1.1-0.60.6-0.5-0.90.7-0.8
Extinction: sum of active levers before priming0.70.72.30.2-0.7-0.90.00.7-0.5-1.00.7-1.5
Active lever presses in extinction session 60.20.21.00.2-0.3-0.8-0.20.2-0.2-0.30.2-1.0
Bone: final force0.20.30.60.3-0.80.5-0.40.5-0.8-0.30.70.5
Bone: final moment0.20.40.70.5-0.80.3-0.50.6-0.8-0.30.90.7
Food consumed during 24 hour testing period1.01.21.9-1.10.71.00.8-1.11.01.4-1.11.3
Glucose0.30.40.80.6-0.9-0.1-0.60.7-0.8-0.50.7-0.3
Heart weight0.60.91.81.2-1.1-1.2-1.30.6-0.6-0.40.4-0.9
Delay discount hyperbolic model param0.50.51.20.8-0.6-1.1-0.50.5-0.4-0.90.7-0.9
Intermittent access intake day 1-15 change0.00.00.10.1-0.2-0.3-0.20.1-0.2-0.00.10.1
Intermittent access intake escalation0.10.10.20.2-0.4-0.3-0.20.3-0.4-0.30.3-0.3
Intermittent access intake escalation 20.30.30.8-0.70.40.90.3-0.50.50.7-0.50.5
Intermitt. access day 1 inactive lever presses1.31.43.20.9-0.9-1.1-1.41.1-0.7-1.50.7-1.8
Intermitt. access day 15 inactive lever presses0.50.61.40.4-0.70.6-1.20.8-0.7-0.80.6-0.8
Intermitt. access escalation Index0.50.41.1-0.50.80.10.1-0.70.80.4-0.81.0
Intermittent access day 1 total infusions0.20.20.70.8-0.0-0.3-0.80.1-0.1-0.4-0.0-0.4
Intermittent access day 15 total infusions0.30.30.90.9-0.4-0.3-1.00.5-0.5-0.60.3-0.1
Intermittent access terminal intake (last 3 days)0.30.31.30.9-0.4-0.1-1.10.3-0.4-0.30.2-0.1
Intermittent access total infusions0.20.30.90.8-0.2-0.1-0.90.3-0.4-0.50.1-0.5
Intermittent access day 1 locomotion0.30.30.80.9-0.1-0.8-0.90.2-0.1-0.6-0.0-0.8
Intermittent access day 15 total locomotion0.20.31.20.6-0.3-0.1-1.10.2-0.3-0.40.2-0.6
Intermittent access total locomotion0.40.41.40.8-0.1-0.7-1.20.1-0.1-0.5-0.2-1.1
Intermittent access standard deviation0.70.81.60.2-0.91.3-0.81.0-0.9-0.91.10.1
Left kidney weight3.810.816.74.1-3.3-3.2-3.63.4-3.0-3.22.9-2.5
Right kidney weight3.59.815.53.9-3.1-3.2-3.73.1-2.8-2.92.6-2.6
Cocaine induced anxiety0.30.41.9-0.50.11.40.5-0.50.10.7-0.6-0.2
Post-drug Anxiety0.20.31.6-0.0-0.61.30.20.2-0.6-0.00.3-0.2
Baseline Anxiety0.40.40.80.6-0.6-0.5-0.50.6-0.6-0.60.8-0.9
Tail length0.41.12.90.31.3-1.40.5-0.81.00.6-1.01.7
Length with tail0.10.20.70.9-0.1-0.8-0.30.3-0.3-0.20.30.5
Length without tail1.12.34.01.4-2.0-0.2-1.31.8-2.0-1.11.9-1.2
Times rat made contact with spout0.80.91.50.5-1.20.9-0.91.1-1.1-0.91.1-0.4
Lifetime Intake0.10.10.60.8-0.1-0.2-0.60.0-0.2-0.2-0.0-0.3
Liver weight, left0.10.10.40.2-0.2-0.0-0.60.1-0.0-0.10.10.6
Liver weight, right1.93.16.01.9-1.8-1.2-2.41.7-1.7-1.91.7-1.2
Locomotor activity0.60.95.71.2-0.3-2.4-0.50.40.1-0.30.30.0
Locomotor testing distance0.30.42.40.8-0.3-1.6-0.40.40.0-0.40.30.0
Locomotor testing rearing0.91.33.31.3-1.1-1.3-1.01.3-0.6-1.81.1-0.4
Locomotion in novel chamber1.41.82.5-1.31.31.40.8-1.41.21.4-1.41.6
Locomotion in novel chamber post-restriction1.72.04.8-0.81.50.31.0-1.81.42.2-1.51.3
Fecal boli incidents, locomotor time 10.60.61.21.1-1.0-0.6-0.90.8-1.1-0.30.8-0.1
Change in fecal boli incidents, locomotor task0.50.51.90.7-0.4-1.4-0.00.5-0.3-0.80.3-0.8
Time >=10cm from walls, locomotor time 10.60.61.60.7-1.0-0.4-0.60.8-0.7-0.60.5-1.3
Bouts of movement, locomotor time 10.20.20.9-0.10.20.5-0.1-0.40.00.7-0.40.9
Total resting periods, locomotor time 10.10.10.60.2-0.10.5-0.4-0.1-0.20.4-0.10.8
Rest time, locomotor task time 12.93.35.61.6-2.30.4-1.92.0-2.4-1.52.0-1.2
Distance moved, locomotor task time 10.60.71.4-0.81.1-0.60.8-0.91.20.4-0.90.6
Vertical activity count, locomotor time 10.91.01.5-1.21.10.70.7-1.11.20.8-1.10.5
Time >=10cm from walls, locomotor time 20.30.31.9-0.2-0.31.4-0.50.2-0.20.10.2-0.3
Bouts of movement, locomotor time 20.90.92.00.7-0.8-0.4-0.81.1-1.0-1.41.1-1.0
Total resting periods, locomotor time 20.90.91.70.7-0.9-0.3-0.91.1-1.1-1.31.0-1.1
Rest time, locomotor task time 20.10.10.20.4-0.4-0.1-0.50.2-0.3-0.0-0.1-0.4
Distance moved, locomotor task time 20.60.72.0-1.20.71.40.5-0.60.60.8-0.50.8
Vertical activity count, locomotor time 20.50.51.9-1.10.61.40.7-0.50.50.4-0.30.2
Light reinforcement 10.10.10.5-0.10.00.7-0.4-0.0-0.10.1-0.20.6
Light reinforcement 20.20.20.90.1-0.41.0-0.50.2-0.40.30.30.6
Bone: marrow area0.61.32.01.1-1.4-0.4-1.21.4-1.2-1.31.1-0.7
Bone: maximum diameter5.19.412.02.9-3.3-1.4-3.53.4-3.2-3.43.3-2.7
Bone: maximum force0.20.40.90.6-0.90.3-0.90.6-0.8-0.40.5-0.4
Bone: maximum moment0.40.61.10.8-1.10.1-1.10.8-1.0-0.50.8-0.3
Mean time between licks in bursts0.50.71.30.3-0.90.4-0.80.9-1.1-0.71.1-0.9
Mean num. licks in bursts1.41.72.70.9-1.4-0.5-1.11.5-1.4-1.41.4-1.7
Cd content in liver0.40.53.5-0.6-0.31.9-0.20.1-0.30.30.00.1
Co content in liver0.60.71.60.7-1.1-0.0-0.90.8-0.8-0.70.6-1.3
Cu content in liver1.51.94.9-1.41.02.20.8-1.10.81.5-1.01.7
Fe content in liver0.80.92.3-1.00.61.50.7-0.80.51.1-0.71.3
K content in liver0.30.30.80.6-0.3-0.8-0.40.6-0.3-0.90.2-0.1
Mg content in liver0.20.20.60.4-0.2-0.3-0.40.6-0.3-0.80.1-0.3
Mn content in liver2.52.85.11.5-1.7-0.6-1.62.0-1.7-2.31.8-1.4
Na content in liver0.10.10.3-0.10.5-0.30.4-0.10.4-0.3-0.40.3
Rb content in liver0.10.10.4-0.10.2-0.10.5-0.20.20.3-0.30.6
Se content in liver1.11.42.2-1.31.50.81.5-1.11.11.0-1.21.0
Sr content in liver0.40.40.8-0.70.50.80.4-0.50.50.5-0.50.9
Zn content in liver0.10.10.70.10.1-0.10.1-0.30.30.5-0.8-0.1
Bone: minimum diameter0.50.81.70.3-1.10.7-0.91.0-1.1-0.91.3-0.4
Time in familiar zone, hab. session 15.55.18.1-2.62.70.92.8-2.32.51.7-1.62.4
Time in novel zone, hab. session 14.14.06.22.4-2.2-1.2-2.52.0-2.1-1.61.3-2.2
Total zone transitions, hab. session 14.46.28.82.4-2.6-1.8-2.42.8-2.6-3.02.6-2.1
Total locomotion distance, hab. session 12.63.75.82.1-1.7-2.4-1.61.9-1.8-2.21.7-1.7
Locomotion velocity, hab. session 13.55.07.22.2-2.1-2.4-1.82.3-2.1-2.72.2-2.1
Time in familiar zone, hab. session 20.40.40.7-0.70.8-0.10.8-0.60.80.1-0.7-0.3
Time in novel zone, hab. session 21.81.82.71.6-1.6-0.7-1.71.3-1.5-0.81.5-0.7
Total zone transitions, hab. session 24.05.16.42.5-2.5-1.8-2.32.4-2.4-2.32.1-1.8
Total locomotion distance, hab. session 22.02.65.52.0-1.5-2.4-1.31.5-1.4-1.51.2-1.5
Locomotion velocity, hab. session 22.02.75.22.0-1.6-2.3-1.41.5-1.5-1.71.3-1.6
Novel to familiar place preference ratio0.10.10.6-0.00.0-0.7-0.00.2-0.2-0.20.3-0.8
Novelty place preference0.20.20.70.2-0.2-0.9-0.30.4-0.4-0.30.5-0.7
Time in novel zone, NPP test0.50.51.20.6-0.4-1.1-0.50.6-0.7-0.60.8-0.8
Total zone transitions, NPP test8.311.817.24.1-3.7-3.2-3.63.5-3.5-3.22.9-2.9
Total locomotion distance, NPP test5.27.210.33.2-2.6-3.1-2.52.8-2.6-2.82.4-1.9
Locomotion velocity, NPP test3.75.38.02.8-2.2-2.7-2.12.4-2.2-2.41.9-1.8
Intraocular pressure0.81.11.71.1-1.2-0.6-0.81.3-1.1-1.21.3-0.2
Delta distance traveled before/after self-admin1.21.32.5-1.61.30.31.6-1.11.30.7-1.10.3
Delta ambulatory time before/after self-admin0.91.01.8-1.41.20.01.2-1.11.20.7-1.00.4
Parametrial fat weight0.30.72.0-0.70.61.10.4-0.60.70.5-0.71.4
Pavlov. Cond. lever latency1.21.52.3-1.31.50.61.4-1.21.50.8-0.81.5
Pavlov. Cond. magazine entry latency2.73.44.91.7-2.2-0.3-2.02.0-2.2-1.91.8-1.7
Pavlov. Cond. change in total contacts0.70.71.60.7-1.10.3-1.30.8-1.1-0.50.4-1.0
Pavlov. Cond. index score2.02.53.61.6-1.9-0.5-1.91.6-1.9-1.31.3-1.8
Pavlov. Cond. latency score2.12.73.81.7-1.9-0.8-1.81.7-2.0-1.31.3-1.8
Pavlov. Cond. lever contacts1.61.83.41.4-1.6-0.7-1.51.3-1.6-0.91.0-1.8
Pavlov. Cond. magazine entry number1.21.52.3-1.11.50.01.5-1.21.51.1-1.11.3
Pavlov. Cond. intertrial magazine entries3.34.04.4-2.12.01.72.1-2.12.12.1-1.91.9
Pavlov. Cond. lever-magazine prob. diff.1.72.13.31.4-1.7-0.3-1.81.4-1.7-1.11.0-1.8
Pavlov. Cond. response bias0.70.81.50.7-1.20.6-1.20.9-1.2-0.60.7-0.9
Pavlov. Cond. lever latency0.30.40.8-0.80.90.70.6-0.60.8-0.1-0.20.6
Pavlov. Cond. magazine entry latency1.41.62.41.3-1.5-0.4-1.41.4-1.6-1.01.2-1.3
Pavlov. Cond. change in total contacts1.21.62.51.6-1.5-1.3-1.31.3-1.5-0.81.2-0.7
Pavlov. Cond. index score0.30.40.90.8-0.9-0.3-0.70.7-0.9-0.10.5-0.6
Pavlov. Cond. latency score0.50.61.10.9-1.0-0.4-0.80.8-1.0-0.30.6-0.7
Pavlov. Cond. lever contacts0.40.51.10.8-1.1-0.3-0.80.7-0.9-0.00.3-0.6
Pavlov. Cond. magazine entry number0.81.01.7-0.71.2-0.31.0-1.21.30.8-1.10.8
Pavlov. Cond. intertrial magazine entries4.76.18.6-2.92.71.52.7-2.62.62.5-2.51.8
Pavlov. Cond. lever-magazine prob. diff.0.60.71.31.0-1.1-0.4-0.91.0-1.1-0.40.7-0.8
Pavlov. Cond. response bias0.50.71.50.9-1.2-0.0-1.00.9-1.2-0.30.6-0.7
Time in closed arm before self-admin0.91.03.10.40.9-1.80.5-0.80.80.8-0.71.4
Time in closed arm after self-admin0.30.30.60.7-0.3-0.8-0.60.5-0.4-0.50.5-0.2
Time in open arm before self-admin0.30.31.7-0.8-0.31.30.30.2-0.30.10.20.2
Time in open arm after self-admin0.70.81.8-1.31.01.01.0-0.81.00.3-0.9-0.3
Bone: periosteal estimation1.83.75.21.7-2.3-0.4-2.22.3-2.2-2.02.1-1.3
Bone: periosteal perimeter3.76.28.22.1-2.9-0.6-2.82.8-2.6-2.82.7-2.3
Bone: post-yield work0.30.42.1-0.50.21.5-0.2-0.40.20.8-0.40.8
Progressive ratio test 1 active lever presses0.20.20.80.40.1-0.9-0.1-0.10.2-0.0-0.5-0.6
Progressive ratio test 1 breakpoint0.30.41.40.8-0.2-1.2-0.50.2-0.1-0.3-0.2-0.9
Progressive ratio test 1 inactive lever presses0.20.20.80.30.1-0.9-0.1-0.00.2-0.3-0.4-0.8
Progressive ratio test 2 active lever presses0.30.30.50.7-0.7-0.3-0.40.6-0.7-0.50.5-0.5
Progressive ratio test 2 breakpoint0.10.10.20.5-0.4-0.2-0.20.3-0.3-0.30.2-0.2
Progressive ratio test 2 inactive lever presses0.20.20.3-0.40.40.40.5-0.40.50.3-0.50.4
Incentive Sensitization - Responses1.01.11.80.6-1.31.1-0.91.2-1.2-0.91.2-0.1
Incentive Sensitization - Breakpoint0.90.91.60.7-1.31.1-1.01.0-1.2-0.71.0-0.0
Sum of active levers in priming session hrs 5-61.91.83.71.4-1.4-0.9-1.01.2-1.3-1.41.3-1.9
Progressive ratio1.92.23.21.6-1.6-1.1-1.51.6-1.7-1.11.8-1.2
Food seeking constrained by brief footshock0.50.61.40.6-0.80.8-1.20.7-0.8-0.40.6-0.8
Seeking ratio, punishment vs. effort0.50.62.2-0.90.61.50.2-0.70.70.5-1.00.5
Retroperitoneal fat weight0.62.04.71.9-1.1-2.2-1.51.3-1.0-1.41.40.1
Reaction time number correct0.10.20.70.00.1-0.8-0.20.10.4-0.9-0.10.0
Reaction time mean minus median0.30.41.10.9-0.6-0.6-0.80.3-0.4-0.20.3-1.0
Reaction time mean minus median AUC0.60.81.61.3-1.1-0.6-1.10.8-0.7-0.70.7-0.9
Reaction time num false alarms0.91.21.7-1.21.20.41.2-1.11.21.3-1.20.6
Reaction time num false alarms AUC1.41.92.5-1.51.60.81.4-1.51.51.6-1.60.6
Reaction time trials correct on left0.10.20.70.00.1-0.8-0.20.10.4-0.9-0.10.0
Reaction time trials on left0.10.20.70.00.1-0.8-0.20.10.4-0.8-0.10.0
Reaction time mean0.20.21.2-0.1-0.51.1-0.20.4-0.4-0.10.5-0.2
Reaction time mean AUC0.20.21.5-0.5-0.11.20.2-0.0-0.00.30.20.2
Median of all reaction times0.30.43.0-0.7-0.11.70.30.1-0.20.20.30.4
Reaction time omissions0.10.20.80.00.0-0.30.3-0.60.40.9-0.4-0.2
Reaction time false alarm rate1.11.53.0-1.21.31.01.3-1.31.11.7-1.20.6
Reaction time premature initiation rate0.20.31.5-0.50.41.20.2-0.20.3-0.10.20.8
Reaction time premature initiations0.10.10.3-0.20.20.6-0.1-0.00.4-0.50.20.5
Std. dev. reaction times0.00.10.20.2-0.30.1-0.30.0-0.10.20.2-0.5
Reaction time trials completed0.10.20.70.00.1-0.8-0.20.10.4-0.8-0.10.0
Reaction time trials AUC0.10.10.4-0.10.2-0.6-0.1-0.00.5-0.7-0.20.0
Run reversals in cocaine runway, females0.30.31.20.20.4-1.10.8-0.20.6-0.1-0.40.5
Run reversals in cocaine runway, males1.31.32.20.6-1.31.1-1.51.2-1.3-0.91.1-0.8
Latency to leave start box in cocaine runway2.62.83.8-1.91.71.71.9-1.71.61.7-1.61.2
Latency to leave start box in cocaine runway, F1.61.83.8-1.41.50.41.9-1.41.51.1-1.11.1
Latency to leave start box in cocaine runway, M1.81.75.9-1.40.92.40.8-1.10.91.3-1.31.0
Std. dev. time between licks in bursts0.10.20.5-0.3-0.20.30.00.3-0.4-0.70.4-0.6
Total sessions with >9 infusions0.10.10.30.40.1-0.5-0.1-0.30.10.2-0.30.1
Short access day 1 total inactive lever presses0.30.31.0-0.10.5-0.4-0.0-0.30.7-0.3-0.8-1.0
Short access day 10 total inactive lever presses1.41.63.10.8-1.2-0.3-1.41.4-1.0-1.70.9-1.8
Short access day 1 total infusions0.20.20.40.30.4-0.5-0.3-0.40.5-0.1-0.6-0.5
Short access day 10 total infusions0.40.41.21.1-0.3-0.9-0.80.4-0.5-0.70.2-0.6
Short access total infusions0.10.10.40.60.1-0.6-0.1-0.20.10.1-0.4-0.5
Short access day 1 locomotion0.40.42.20.10.6-1.50.5-0.40.6-0.3-0.5-0.5
Short access day 10 total locomotion1.01.22.91.0-1.0-0.8-1.50.8-0.9-1.00.6-1.7
Short access total locomotion0.80.83.11.1-0.4-1.8-0.70.4-0.4-0.80.2-1.2
One hour access (0.3 mA shock)0.50.50.7-0.60.70.40.8-0.80.80.7-0.80.8
Compulsive drug intake2.12.25.0-1.71.6-0.02.2-1.31.81.0-1.31.3
One hour access (shock baseline)0.20.21.30.1-0.31.1-0.5-0.1-0.20.30.00.4
Social response proportion0.50.61.4-0.70.70.60.2-0.90.61.2-1.1-0.2
Social responses0.20.21.5-0.60.01.2-0.30.1-0.1-0.0-0.00.1
Social time0.20.21.5-0.40.01.2-0.2-0.30.30.3-0.20.0
Soleus weight1.23.55.12.1-1.9-1.2-1.92.2-2.1-1.82.30.1
Bone: stiffness0.20.32.1-0.3-0.31.4-0.5-0.1-0.10.3-0.10.1
Tibialis anterior weight0.93.16.52.6-1.7-2.2-1.91.6-1.6-1.31.5-0.7
Time to tail flick, vehicle, before self-admin0.10.10.5-0.10.00.20.10.3-0.0-0.50.20.7
Time to tail flick, vehicle, after self-admin0.80.91.61.1-0.7-1.3-0.51.0-0.7-1.10.8-1.2
Time to tail flick, test, before self-admin0.80.82.2-0.80.71.30.2-0.80.70.9-0.61.5
Time to tail flick, test, after self-admin0.50.51.10.4-0.5-0.3-0.41.0-0.6-1.00.80.9
Delta time to tail flick, vehicle, before/after SA0.60.62.01.0-0.5-1.2-0.40.4-0.5-0.20.2-1.4
Delta time to tail flick, test, before/after SA0.40.31.10.5-0.2-1.1-0.00.7-0.3-0.80.40.4
Tibia length0.20.62.31.1-0.6-0.9-0.60.2-0.30.50.21.5
Ambulatory time before self-admin1.81.93.01.7-1.5-1.3-1.71.4-1.4-1.11.1-1.0
Ambulatory time after self-admin0.20.21.20.20.1-1.1-0.2-0.10.20.0-0.4-0.5
Bone: tissue strength0.30.31.90.10.20.2-0.0-0.30.30.5-0.31.4
Total heroin consumption0.40.51.30.3-0.81.1-0.30.8-0.7-0.80.9-0.2
Bone: trabecular number0.91.42.6-1.61.01.51.2-1.20.91.3-1.00.6
Bone: trabecular spacing0.10.10.80.20.1-0.90.10.10.1-0.30.20.4
Bone: trabecular thickness0.20.21.90.50.0-1.40.10.10.0-0.20.1-0.0
Bone: trabecular tissue density1.31.83.61.8-1.1-1.9-1.11.2-0.9-1.30.9-1.5
Water consumed over 24 hours0.20.30.9-0.50.10.90.3-0.20.30.4-0.20.9
Number of responses in last shaping day0.30.31.50.40.2-1.2-0.40.20.2-0.7-0.3-0.1