Rnf7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	OFC	gene expression	Rnf7	0.46	0.15	7.7e-04	0.07	0.1	0.1	0.11	7.9e-03	2.2e-03	1.9e-03	1.2e-03
2	BLA	gene expression	Rnf7	0.08	0.06	9.3e-03	0.07	0.01	0.04	0.04	1.2e-04	5.5e-02	2.6e-03	2.5e-03
3	Liver	mRNA stability	Rnf7	0.05	0.03	1.0e-03	0.03	0.02	0.03	0.03	1.3e-04	2.3e-03	4.5e-04	5.4e-04
4	Brain	mRNA stability	Rnf7	0.17	0.07	1.1e-09	0.08	0.09	0.1	0.11	7.6e-08	4.4e-09	1.7e-09	3.2e-10
5	Liver	gene expression	Rnf7	0.05	0.03	1.7e-05	0.04	0.02	0.02	0.01	7.2e-05	4.8e-03	4.0e-03	9.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5
Bone: apparent density	0.3	0.5	1.6	-0.5	0.4	-1.3	0.6	0.0
Area under the delay curve	0.4	0.4	1.0	0.4	-0.3	-0.2	1.0	-0.9
BMI with tail	2.4	7.9	21.7	4.7	-2.5	1.7	-2.6	1.3
BMI without tail	3.3	6.8	22.3	4.7	-3.2	0.9	-0.2	-0.9
Body weight	3.1	12.8	27.6	5.3	-4.3	3.5	-2.3	0.3
Weight adjusted by age	1.2	1.4	3.8	0.8	-0.9	2.0	-1.3	0.2
Bone surface	0.4	0.6	1.3	-0.5	-0.2	-1.0	1.1	-0.7
Bone volume	0.2	0.3	0.7	-0.5	-0.0	-0.8	0.7	-0.3
Breakpoint value in progressive ratio session	1.5	1.7	3.1	-1.8	1.4	-1.7	0.6	-0.2
Number of licking bursts	1.0	1.1	1.9	0.7	-1.3	-0.4	1.2	-1.4
Context. condit. distance diff. score	1.5	1.8	2.9	-1.6	1.7	-0.3	-1.3	1.4
Locomotion velocity, session 1	0.4	0.4	0.9	0.5	0.2	-0.5	-1.0	0.8
Locomotion distance, session 1	1.3	1.6	4.2	0.9	-0.0	0.1	-2.1	1.7
Locomotion velocity, session 2	1.6	1.9	4.7	1.4	-0.5	-0.7	-2.2	1.5
Locomotion distance, session 2	2.0	2.7	4.6	2.2	-1.5	0.1	-2.1	1.5
Locomotion velocity, session 3	1.6	1.9	5.2	2.3	-1.5	-0.4	1.0	-0.9
Locomotion distance, session 3	0.2	0.2	1.0	0.2	-1.0	-0.3	-0.2	0.0
Stereotopy head waving bouts, day 3	4.8	5.6	9.9	2.2	-2.5	1.7	2.1	-3.1
Stereotopy head waving duration, day 3	3.3	3.9	6.1	2.4	-1.9	1.1	1.7	-2.5
Locomotion velocity, session 7	1.1	1.2	2.5	1.4	0.2	0.1	-1.3	1.6
Locomotion distance, session 7	0.4	0.5	1.3	-0.1	0.1	0.2	-1.1	1.1
Stereotopy head waving bouts, day 7	2.2	2.5	4.4	-1.0	1.6	-2.1	1.6	-1.3
Stereotopy head waving duration, day 7	2.2	2.6	5.4	-0.3	0.9	-1.9	2.3	-1.8
Locomotion velocity, session 8	1.7	2.0	5.1	0.6	1.1	-2.2	-1.0	1.6
Locomotion distance, session 8	1.1	1.6	3.9	-0.1	0.7	-0.2	-2.0	1.9
Degree of sensitization distance	0.8	0.8	1.5	-0.5	1.1	0.2	-0.9	1.2
Degree of sensitization stereotypy	3.2	3.5	7.4	-1.9	2.7	-2.5	0.1	0.4
Conditioned locomotion	2.3	2.7	5.7	-1.7	2.0	-2.4	-0.1	0.9
Cocaine response after cond. corrected	1.3	1.4	2.8	1.7	-1.4	0.5	0.9	-1.2
Cocaine response after cond. not corrected	2.3	2.5	4.3	2.1	-2.0	1.0	1.0	-1.6
Cocaine response before conditioning	0.6	0.8	1.2	0.7	-1.1	1.0	0.5	-0.9
Saline control response	0.8	1.0	1.9	1.2	-0.7	0.4	-1.4	1.0
Bone: connectivity density	0.8	1.2	2.5	-1.3	1.3	-1.6	0.6	0.1
Bone: cortical apparent density	0.6	0.7	2.5	-0.7	1.6	-0.6	-0.1	0.6
Bone: cortical area	1.0	1.5	4.2	0.7	0.5	-0.4	-1.5	2.1
Bone: cortical porosity	2.1	2.3	5.4	-0.9	1.3	-0.3	-1.9	2.3
Bone: cortical porosity	3.4	3.7	8.3	-1.3	1.9	-0.2	-2.2	2.9
Bone: cortical thickness	0.5	0.8	2.5	0.8	0.3	0.1	-0.9	1.6
Bone: cortical thickness	0.5	0.6	1.5	0.1	0.5	-1.2	-0.6	0.9
Bone: cortical tissue density	0.5	0.7	2.4	-0.7	1.5	-0.5	-0.1	0.6
Condit. Reinf. active minus inactive responses	0.3	0.4	0.8	0.9	-0.8	-0.4	0.2	-0.4
Condit. Reinf. active-inactive response ratio	1.0	1.0	3.0	1.7	-0.8	-0.2	-0.9	0.8
Condit. Reinf. active responses	0.3	0.3	0.4	0.6	-0.6	-0.6	0.6	-0.5
Condit. Reinf. inactive responses	0.7	0.8	2.2	-0.5	-0.1	-0.5	1.5	-1.1
Incentive salience index mean	0.5	0.6	1.4	1.2	-1.1	0.0	-0.4	0.0
Condit. Reinf. lever presses	0.8	1.1	2.5	1.6	-1.1	0.7	-1.0	0.4
Condit. Reinf. active minus inactive responses	1.4	1.8	2.8	1.4	-1.4	-0.1	1.7	-1.4
Condit. Reinf. active-inactive response ratio	4.8	5.0	9.8	3.1	-2.7	0.9	1.9	-1.9
Condit. Reinf. active responses	0.6	0.8	2.4	0.3	-0.5	-0.2	1.6	-1.2
Condit. Reinf. inactive responses	0.9	1.1	2.9	-1.7	1.5	-0.5	0.0	0.5
Condit. Reinf. lever presses	1.5	2.1	2.6	1.4	-1.6	1.1	1.6	-1.4
Condit. Reinf. lever reinforcers received	0.4	0.5	1.6	0.2	-0.3	0.1	1.3	-0.9
Conditioned reinforcement - actives	0.4	0.4	1.2	0.1	-0.5	1.1	0.3	-0.6
Conditioned reinforcement - inactives	0.7	0.8	3.0	-0.8	-0.3	1.7	0.1	-0.5
Conditioned locomotion	0.3	0.3	0.8	-0.1	0.0	0.0	-0.8	0.9
Patch foraging indifference point 0 sec	0.1	0.1	0.2	0.3	-0.4	-0.5	-0.1	0.4
Patch foraging indifference point AUC	2.0	2.3	5.8	-1.5	2.4	0.1	-1.0	1.5
Delay disc. indifference point, 0s delay	0.9	0.9	2.5	-0.3	-0.1	0.0	1.6	-1.4
Delay disc. indifference point, 16s delay	0.8	0.8	2.4	1.5	-0.9	-0.4	0.8	-0.5
Delay disc. indifference point, 2s delay	1.5	1.6	3.2	1.8	-1.7	0.5	0.7	-1.1
Delay disc. indifference point, 24s delay	0.7	0.7	1.5	-1.1	1.2	-0.4	-0.6	0.5
Delay disc. indifference point, 4s delay	2.2	2.3	5.8	0.5	-0.8	-0.7	2.4	-2.1
Delay disc. indifference point, 8s delay	0.1	0.1	0.1	-0.3	0.3	0.3	0.3	-0.2
Indifference point function ln k	1.7	2.4	5.7	1.5	-2.4	-0.2	1.0	-1.7
Indifference point function log k	1.7	2.4	5.7	1.5	-2.4	-0.2	1.0	-1.7
Patch foraging total patch changes 0 sec	0.1	0.1	0.2	0.5	-0.5	-0.2	-0.2	0.4
Patch foraging total patch changes 12 sec	3.2	4.2	6.1	-2.0	2.4	0.7	-2.2	2.5
Patch foraging total patch changes 18 sec	0.5	0.7	1.4	-0.4	1.0	-0.6	-0.8	1.2
Patch foraging total patch changes 24 sec	0.3	0.4	0.9	-0.6	0.9	0.6	-0.1	0.6
Patch foraging total patch changes 6 sec	0.7	1.0	1.7	-0.7	1.3	-1.2	-0.4	1.2
Patch foraging time to switch 0 sec	1.2	1.8	4.3	-1.7	1.2	-2.1	0.8	-0.1
Patch foraging water rate 0 sec	1.2	2.0	4.1	2.0	-1.5	1.8	0.1	-0.6
Patch foraging water rate 12 sec	1.9	3.0	5.8	2.4	-2.4	1.7	0.1	-0.7
Patch foraging water rate 18 sec	2.9	3.8	7.1	2.6	-2.1	2.7	-0.7	0.0
Patch foraging water rate 24 sec	1.6	2.3	4.6	2.1	-2.0	1.1	0.8	-1.1
Patch foraging water rate 6 sec	3.3	4.8	8.1	2.8	-2.8	2.5	0.6	-1.1
Seeking ratio, delayed vs. immediate footshock	5.8	6.7	13.2	-1.9	3.6	-3.0	-1.1	2.5
Distance traveled before self-admin	0.9	1.0	2.2	0.9	-0.5	0.2	-1.5	1.3
Distance traveled after self-admin	0.2	0.3	0.7	0.0	-0.0	0.2	-0.7	0.8
Extensor digitorum longus weight	1.0	3.9	9.7	3.1	-2.1	1.4	-1.7	0.9
Bone: elastic displacement	1.6	1.8	4.7	0.2	0.3	0.3	-2.2	2.0
Bone: elastic work	0.6	0.8	1.9	0.5	-0.1	-0.3	-1.3	1.4
Bone: endosteal estimation	0.3	0.6	1.5	1.2	-0.9	-0.7	-0.5	0.2
Bone: endosteal perimeter	0.6	1.2	3.0	0.5	0.0	-0.4	-1.7	1.5
Epididymis fat weight	0.4	0.9	1.7	1.0	-0.6	1.3	-0.9	0.6
Delta time in closed arm before/after self-admin	1.9	1.9	3.3	-1.6	1.8	-0.4	-1.0	1.5
Delta time in open arm before/after self-admin	0.5	0.4	0.6	-0.7	0.4	-0.8	-0.6	0.8
Diff in mean of infusions in LGA sessions	0.4	0.5	0.8	-0.5	0.2	-0.9	0.9	-0.7
Delay discount exponential model param	0.4	0.4	1.0	-0.4	0.3	0.3	-1.0	0.9
Extinction: sum of active levers before priming	2.8	2.8	4.4	-2.1	1.9	0.2	-1.6	1.8
Active lever presses in extinction session 6	1.4	1.4	2.7	-1.6	1.3	-0.1	-0.9	1.3
Bone: final force	0.6	0.9	2.3	1.5	-1.1	-0.5	0.8	-0.5
Bone: final moment	0.9	1.5	3.9	2.0	-1.4	-0.4	0.9	-0.7
Food consumed during 24 hour testing period	0.8	1.0	1.6	0.0	-0.8	1.3	1.2	-1.1
Glucose	0.1	0.2	0.5	0.7	-0.1	-0.3	-0.0	0.6
Heart weight	1.3	1.8	7.0	0.5	-0.5	2.6	-1.0	0.6
Delay discount hyperbolic model param	0.6	0.6	1.2	-0.6	0.6	0.2	-1.1	1.1
Intermittent access intake day 1-15 change	0.8	0.8	3.3	0.3	-0.3	1.8	0.1	-0.5
Intermittent access intake escalation	0.5	0.5	2.3	0.1	0.1	1.5	-0.2	-0.1
Intermittent access intake escalation 2	0.3	0.3	0.5	-0.6	0.2	0.1	0.7	-0.7
Intermitt. access day 1 inactive lever presses	2.1	2.2	3.5	-1.4	1.7	0.2	-1.9	1.7
Intermitt. access day 15 inactive lever presses	0.4	0.5	1.3	-1.1	0.5	-0.4	-0.7	0.2
Intermitt. access escalation Index	0.8	0.7	2.1	-0.2	-0.3	-0.1	1.2	-1.4
Intermittent access day 1 total infusions	0.1	0.2	0.4	-0.1	-0.3	0.6	-0.6	-0.0
Intermittent access day 15 total infusions	1.2	1.4	5.1	0.8	-0.9	2.3	-0.3	-0.4
Intermittent access terminal intake (last 3 days)	1.1	1.3	4.7	0.5	-1.0	2.2	-0.2	-0.5
Intermittent access total infusions	0.4	0.5	2.1	-0.2	-0.2	1.4	-0.6	0.1
Intermittent access day 1 locomotion	0.2	0.3	1.0	0.0	-0.2	0.2	-1.0	0.4
Intermittent access day 15 total locomotion	0.1	0.1	0.1	-0.0	0.2	-0.0	-0.4	0.4
Intermittent access total locomotion	0.6	0.7	1.1	-1.0	0.8	0.1	-1.0	0.8
Intermittent access standard deviation	0.2	0.2	0.6	0.8	-0.4	0.3	0.2	-0.3
Left kidney weight	1.6	4.6	7.0	2.4	-2.3	1.5	-2.6	1.7
Right kidney weight	1.8	5.1	7.9	2.2	-2.2	2.3	-2.8	1.6
Cocaine induced anxiety	0.9	1.0	2.9	-1.7	1.1	-0.6	-0.3	0.6
Post-drug Anxiety	0.3	0.4	0.9	-1.0	0.4	0.6	-0.4	0.5
Baseline Anxiety	0.7	0.8	2.5	0.0	0.1	1.6	-0.8	0.9
Tail length	2.0	6.1	11.0	2.7	-3.3	1.7	1.6	-2.5
Length with tail	1.0	3.8	7.6	1.7	-2.8	2.6	0.1	-1.2
Length without tail	1.0	2.2	5.6	0.2	-1.3	2.4	-1.7	0.8
Times rat made contact with spout	0.8	0.9	4.1	-0.3	-0.5	2.0	-0.6	0.2
Lifetime Intake	0.3	0.3	1.3	-0.1	-0.3	1.1	-0.4	0.0
Liver weight, left	0.6	1.0	1.8	1.2	-1.3	-0.2	0.8	-1.0
Liver weight, right	0.4	0.6	1.0	1.0	-0.7	-0.9	-0.7	0.1
Locomotor activity	1.1	1.7	3.3	1.8	-1.5	1.7	-0.3	-0.3
Locomotor testing distance	0.4	0.7	1.9	1.4	-0.9	0.8	-0.2	-0.2
Locomotor testing rearing	0.4	0.6	1.3	1.0	-0.6	1.1	-0.6	0.1
Locomotion in novel chamber	1.3	1.6	3.8	0.8	0.1	-1.8	1.9	-0.6
Locomotion in novel chamber post-restriction	0.8	0.9	2.3	0.3	-0.3	0.4	1.5	-1.4
Fecal boli incidents, locomotor time 1	1.1	1.3	3.3	1.8	-1.2	1.1	0.2	0.4
Change in fecal boli incidents, locomotor task	0.6	0.5	1.4	0.5	-0.3	-0.5	-1.2	0.7
Time >=10cm from walls, locomotor time 1	0.5	0.5	1.2	-0.9	0.2	0.5	-1.1	0.5
Bouts of movement, locomotor time 1	1.0	1.1	2.2	0.4	-1.5	-0.5	1.0	-1.3
Total resting periods, locomotor time 1	1.0	1.1	2.7	0.7	-1.7	-0.2	0.8	-1.2
Rest time, locomotor task time 1	0.4	0.5	1.1	0.5	-0.4	0.5	-1.1	0.8
Distance moved, locomotor task time 1	0.3	0.3	0.6	0.3	0.4	-0.7	0.8	-0.3
Vertical activity count, locomotor time 1	0.5	0.6	1.0	-0.6	1.0	-0.9	0.7	-0.1
Time >=10cm from walls, locomotor time 2	0.4	0.4	1.1	-0.6	0.8	-1.0	0.0	-0.1
Bouts of movement, locomotor time 2	0.4	0.5	1.0	-0.4	0.3	0.8	-1.0	0.6
Total resting periods, locomotor time 2	0.5	0.5	1.1	-0.5	-0.0	1.0	-1.0	0.5
Rest time, locomotor task time 2	0.1	0.2	0.2	-0.5	-0.5	0.3	-0.4	0.3
Distance moved, locomotor task time 2	0.7	0.9	2.1	0.5	0.3	-1.4	1.2	-0.7
Vertical activity count, locomotor time 2	0.7	0.8	2.4	-0.7	1.5	-0.8	0.2	0.6
Light reinforcement 1	1.2	2.2	6.3	1.2	-1.4	2.5	0.5	-1.2
Light reinforcement 2	0.6	0.8	1.2	1.0	-1.1	0.4	0.6	-1.1
Bone: marrow area	0.3	0.7	1.7	1.3	-0.9	-0.6	-0.6	0.2
Bone: maximum diameter	1.5	2.8	7.1	0.8	0.5	-0.6	-2.4	2.7
Bone: maximum force	0.2	0.3	0.5	0.7	-0.5	-0.6	-0.2	0.5
Bone: maximum moment	0.3	0.5	1.3	1.1	-0.8	-0.5	-0.2	0.4
Mean time between licks in bursts	0.5	0.7	1.0	-0.5	1.0	-0.8	-1.0	0.9
Mean num. licks in bursts	1.8	2.1	3.8	-0.6	0.8	2.0	-1.7	1.7
Cd content in liver	0.1	0.1	0.2	-0.3	0.0	-0.4	0.2	0.1
Co content in liver	0.7	0.9	1.7	-0.6	1.3	-0.6	-1.0	0.9
Cu content in liver	1.2	1.5	3.7	0.3	-0.9	0.3	1.6	-1.9
Fe content in liver	1.0	1.3	2.1	0.3	-1.3	1.0	1.2	-1.5
K content in liver	0.8	0.8	2.6	0.9	-0.5	-1.6	0.2	-0.3
Mg content in liver	0.3	0.3	1.3	0.3	-0.4	-1.1	-0.3	0.1
Mn content in liver	0.5	0.6	1.4	0.1	0.5	-0.3	-1.1	1.2
Na content in liver	0.6	0.6	2.9	-0.0	-0.2	-1.7	0.4	0.2
Rb content in liver	0.7	0.8	1.6	0.8	-1.3	1.0	0.6	-0.8
Se content in liver	0.4	0.4	0.9	-0.3	-0.2	-0.7	0.8	-1.0
Sr content in liver	0.5	0.5	0.9	0.3	-0.5	0.1	1.0	-1.0
Zn content in liver	0.3	0.3	0.9	0.0	-0.7	0.9	-0.2	-0.0
Bone: minimum diameter	0.1	0.2	0.7	0.2	0.3	-0.2	-0.5	0.8
Time in familiar zone, hab. session 1	2.4	2.2	5.6	-0.8	0.9	-0.8	2.4	-1.9
Time in novel zone, hab. session 1	2.5	2.4	5.4	1.0	-1.3	1.2	-2.3	1.6
Total zone transitions, hab. session 1	1.0	1.4	2.8	1.1	0.4	0.2	-1.7	1.6
Total locomotion distance, hab. session 1	0.7	1.0	2.4	0.8	0.1	-0.1	-1.6	1.4
Locomotion velocity, hab. session 1	1.0	1.5	3.4	0.5	0.7	-0.4	-1.7	1.8
Time in familiar zone, hab. session 2	1.2	1.3	2.4	-1.5	1.1	1.5	-0.4	0.5
Time in novel zone, hab. session 2	0.9	0.9	2.3	1.5	-0.7	-1.2	-0.5	0.4
Total zone transitions, hab. session 2	1.1	1.4	2.5	1.6	-0.6	0.7	-1.5	1.2
Total locomotion distance, hab. session 2	0.5	0.7	1.7	0.9	-0.4	0.5	-1.3	0.8
Locomotion velocity, hab. session 2	0.5	0.7	1.8	0.8	-0.3	0.4	-1.3	0.9
Novel to familiar place preference ratio	1.4	1.4	2.3	-0.9	1.1	-1.5	-0.9	1.5
Novelty place preference	0.9	1.0	1.7	-0.5	0.7	-1.3	-0.8	1.3
Time in novel zone, NPP test	0.8	0.9	1.8	-0.2	0.5	-1.1	-1.0	1.3
Total zone transitions, NPP test	2.9	4.2	7.2	2.2	-1.5	1.8	-2.7	1.9
Total locomotion distance, NPP test	1.6	2.2	3.6	1.9	-1.3	1.3	-1.8	0.8
Locomotion velocity, NPP test	1.2	1.8	2.6	1.6	-1.3	1.1	-1.6	0.8
Intraocular pressure	0.7	1.0	2.0	1.4	-1.1	1.1	-0.5	-0.3
Delta distance traveled before/after self-admin	0.6	0.6	1.6	-1.3	1.1	-0.3	0.3	0.1
Delta ambulatory time before/after self-admin	0.4	0.4	0.8	-0.9	0.9	-0.4	0.4	-0.3
Parametrial fat weight	0.9	1.7	2.6	1.0	-1.2	1.0	1.6	-1.6
Pavlov. Cond. lever latency	0.9	1.1	2.2	-0.5	0.3	1.1	1.5	-1.3
Pavlov. Cond. magazine entry latency	0.8	1.0	3.0	0.6	-0.2	0.0	-1.7	1.2
Pavlov. Cond. change in total contacts	0.3	0.3	0.9	0.0	-0.3	0.0	-1.0	0.7
Pavlov. Cond. index score	0.9	1.1	3.1	0.4	-0.1	-0.5	-1.8	1.5
Pavlov. Cond. latency score	0.9	1.2	3.3	0.5	-0.3	-0.3	-1.8	1.4
Pavlov. Cond. lever contacts	1.1	1.3	3.1	-0.1	0.3	-0.8	-1.8	1.6
Pavlov. Cond. magazine entry number	0.4	0.5	1.6	0.1	-0.2	0.5	1.3	-0.9
Pavlov. Cond. intertrial magazine entries	1.0	1.2	3.0	-0.9	0.0	-1.0	1.7	-1.2
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.1	3.1	0.2	-0.0	-0.5	-1.8	1.5
Pavlov. Cond. response bias	0.3	0.3	0.7	0.2	-0.0	-0.8	-0.8	0.6
Pavlov. Cond. lever latency	0.5	0.7	1.0	-0.9	0.8	-1.0	0.6	-0.9
Pavlov. Cond. magazine entry latency	1.3	1.5	3.2	0.1	-0.5	1.8	-1.6	1.2
Pavlov. Cond. change in total contacts	1.7	2.3	5.9	1.5	-1.5	2.4	-0.7	0.6
Pavlov. Cond. index score	0.7	0.9	2.6	0.5	-0.9	1.6	-0.7	0.5
Pavlov. Cond. latency score	0.7	0.9	2.5	0.4	-0.8	1.6	-0.9	0.7
Pavlov. Cond. lever contacts	0.6	0.8	1.4	0.8	-1.0	1.2	-0.6	0.7
Pavlov. Cond. magazine entry number	0.5	0.7	2.0	-0.1	0.2	-1.4	0.9	-0.7
Pavlov. Cond. intertrial magazine entries	2.9	3.8	9.6	-1.7	1.6	-3.1	1.8	-0.8
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.1	3.1	0.4	-0.8	1.8	-1.0	0.7
Pavlov. Cond. response bias	0.6	0.8	1.9	0.6	-0.8	1.4	-0.6	0.9
Time in closed arm before self-admin	2.2	2.5	3.7	1.9	-1.9	-0.3	1.3	-1.8
Time in closed arm after self-admin	0.0	0.0	0.1	0.2	-0.1	0.3	-0.0	-0.2
Time in open arm before self-admin	0.1	0.2	0.4	-0.3	0.4	0.7	0.3	0.0
Time in open arm after self-admin	1.5	1.7	3.4	-1.8	1.6	-1.0	-0.5	1.0
Bone: periosteal estimation	0.5	1.1	2.2	1.5	-0.4	-0.7	-1.1	1.2
Bone: periosteal perimeter	1.4	2.3	6.0	0.0	1.1	-0.4	-2.1	2.4
Bone: post-yield work	0.4	0.6	0.8	0.8	-0.7	-0.2	0.9	-0.9
Progressive ratio test 1 active lever presses	0.2	0.2	0.5	-0.3	0.1	0.5	-0.7	0.4
Progressive ratio test 1 breakpoint	0.4	0.4	1.0	-0.3	0.2	0.5	-1.0	0.8
Progressive ratio test 1 inactive lever presses	1.0	1.1	2.7	-1.6	0.8	0.9	-1.0	0.6
Progressive ratio test 2 active lever presses	0.3	0.3	1.2	0.1	-0.1	1.1	-0.5	0.2
Progressive ratio test 2 breakpoint	0.2	0.2	0.9	0.0	-0.1	1.0	-0.2	-0.0
Progressive ratio test 2 inactive lever presses	0.6	0.7	2.0	-0.9	0.1	1.4	0.1	-0.7
Incentive Sensitization - Responses	0.7	0.7	3.0	0.5	-0.7	1.7	0.0	-0.3
Incentive Sensitization - Breakpoint	0.7	0.7	2.6	0.6	-0.7	1.6	0.1	-0.4
Sum of active levers in priming session hrs 5-6	2.0	2.0	3.5	-1.5	1.0	0.8	-1.9	1.6
Progressive ratio	0.9	1.0	2.3	1.5	-0.3	-0.9	-1.0	1.0
Food seeking constrained by brief footshock	0.3	0.4	0.9	-0.4	0.7	-0.9	-0.2	0.5
Seeking ratio, punishment vs. effort	0.5	0.6	2.0	-1.4	0.3	0.3	0.7	-0.7
Retroperitoneal fat weight	1.0	3.3	7.0	2.6	-2.4	1.5	0.3	-1.2
Reaction time number correct	0.0	0.1	0.1	-0.3	-0.1	0.4	-0.0	0.0
Reaction time mean minus median	0.5	0.7	1.4	-0.6	0.5	1.0	-1.2	0.8
Reaction time mean minus median AUC	0.4	0.5	1.5	0.1	-0.1	1.2	-1.0	0.4
Reaction time num false alarms	0.1	0.1	0.3	-0.6	0.3	-0.2	0.4	-0.2
Reaction time num false alarms AUC	0.3	0.4	1.0	-1.0	0.7	-0.4	0.5	-0.2
Reaction time trials correct on left	0.0	0.1	0.1	-0.3	-0.1	0.4	-0.0	0.0
Reaction time trials on left	0.0	0.1	0.2	-0.3	-0.1	0.5	-0.0	0.0
Reaction time mean	0.4	0.5	2.2	-0.3	0.1	1.5	-0.4	0.1
Reaction time mean AUC	0.2	0.3	1.3	-0.2	0.1	1.2	-0.0	-0.3
Median of all reaction times	0.3	0.4	1.7	-0.2	0.0	1.3	0.1	-0.4
Reaction time omissions	0.3	0.5	1.4	-0.2	0.7	1.2	-0.3	0.5
Reaction time false alarm rate	0.1	0.2	0.3	-0.3	0.3	-0.5	0.6	-0.4
Reaction time premature initiation rate	0.4	0.6	1.3	-0.6	0.3	-0.3	1.0	-1.1
Reaction time premature initiations	0.2	0.4	0.7	-0.8	0.4	-0.2	0.6	-0.7
Std. dev. reaction times	0.3	0.4	1.0	-0.4	0.4	1.0	-0.7	0.5
Reaction time trials completed	0.0	0.1	0.2	-0.3	-0.1	0.5	-0.0	0.0
Reaction time trials AUC	0.1	0.1	0.3	-0.5	-0.1	0.5	-0.0	0.0
Run reversals in cocaine runway, females	0.6	0.6	1.1	0.5	-0.9	-0.7	0.7	-1.0
Run reversals in cocaine runway, males	0.4	0.4	1.2	-0.0	-0.7	0.4	-1.1	0.2
Latency to leave start box in cocaine runway	1.2	1.2	2.5	-1.6	1.2	-0.5	1.3	-0.7
Latency to leave start box in cocaine runway, F	0.7	0.8	1.2	-1.1	0.8	0.4	1.1	-0.9
Latency to leave start box in cocaine runway, M	1.2	1.2	2.7	-0.6	0.7	-1.7	1.4	-0.6
Std. dev. time between licks in bursts	1.7	2.0	4.1	-1.0	1.7	-2.0	-0.4	1.3
Total sessions with >9 infusions	0.3	0.4	1.0	0.4	-0.7	1.0	-0.1	-0.2
Short access day 1 total inactive lever presses	2.2	2.4	5.4	-2.3	2.0	-0.9	-0.9	1.1
Short access day 10 total inactive lever presses	2.2	2.5	3.4	-1.4	1.6	-1.2	-1.7	1.8
Short access day 1 total infusions	0.3	0.3	1.1	-1.0	0.4	0.5	-0.4	0.3
Short access day 10 total infusions	0.7	0.8	3.2	-0.0	-0.4	1.8	-0.8	0.3
Short access total infusions	0.2	0.2	0.4	-0.6	0.2	0.4	-0.6	0.5
Short access day 1 locomotion	0.5	0.5	1.6	-0.7	1.2	-0.3	-0.2	0.8
Short access day 10 total locomotion	1.9	2.1	3.1	-1.1	1.6	-1.0	-1.5	1.8
Short access total locomotion	0.6	0.7	1.3	-0.5	0.7	0.2	-1.1	1.1
One hour access (0.3 mA shock)	0.5	0.6	1.6	-0.5	-0.2	1.3	0.7	-0.7
Compulsive drug intake	0.5	0.5	1.7	-0.1	0.4	-0.3	1.3	-0.7
One hour access (shock baseline)	0.4	0.5	1.3	-0.5	-0.6	1.1	0.2	-0.7
Social response proportion	0.2	0.2	0.6	-0.8	0.4	-0.2	-0.3	0.3
Social responses	0.2	0.2	0.8	-0.3	0.2	0.9	0.3	-0.4
Social time	0.3	0.4	1.4	-0.7	0.2	1.2	-0.2	-0.0
Soleus weight	1.6	4.6	14.1	3.7	-2.8	0.3	0.3	-0.7
Bone: stiffness	0.1	0.2	0.5	-0.4	0.1	-0.7	0.4	-0.0
Tibialis anterior weight	0.9	2.9	8.0	2.8	-2.3	0.8	-0.9	0.1
Time to tail flick, vehicle, before self-admin	1.0	1.0	2.4	0.8	-0.7	1.5	0.7	-1.1
Time to tail flick, vehicle, after self-admin	0.8	0.9	2.3	-0.3	-0.4	1.5	-1.4	0.2
Time to tail flick, test, before self-admin	1.2	1.2	2.8	0.7	-0.7	0.3	1.5	-1.7
Time to tail flick, test, after self-admin	3.5	3.7	6.6	2.1	-2.6	2.0	0.6	-1.7
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	1.9	-0.5	0.1	-0.5	-1.4	0.8
Delta time to tail flick, test, before/after SA	2.0	1.8	3.8	1.4	-1.9	1.6	0.1	-0.8
Tibia length	2.7	7.6	14.5	3.8	-3.7	1.0	1.5	-2.5
Ambulatory time before self-admin	0.7	0.7	1.1	1.0	-0.6	-0.1	-1.0	1.1
Ambulatory time after self-admin	0.3	0.3	0.7	-0.0	0.2	-0.5	-0.7	0.8
Bone: tissue strength	5.0	4.9	8.0	2.2	-2.4	2.8	1.4	-1.9
Total heroin consumption	1.1	1.3	4.4	-1.1	-0.7	2.1	-0.7	-0.2
Bone: trabecular number	0.9	1.3	3.3	-1.1	1.3	-1.8	0.7	-0.1
Bone: trabecular spacing	0.4	0.5	1.4	0.9	-0.2	1.2	0.6	-0.2
Bone: trabecular thickness	0.2	0.3	0.7	0.8	-0.7	-0.3	-0.1	-0.3
Bone: trabecular tissue density	0.7	1.0	2.7	0.1	-0.3	0.4	-1.6	1.5
Water consumed over 24 hours	0.6	0.7	1.4	0.5	-1.2	0.6	0.8	-1.0
Number of responses in last shaping day	0.1	0.1	0.3	0.3	-0.5	0.3	-0.2	-0.2