Hub : Genes

Rnf7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Rnf7 0.05 0.04 5.1e-03 0.01 0.02 0.01 0.01 2.2e-02 4.0e-03 3.1e-02 5.3e-02
2 NAcc gene expression Rnf7 0.04 0.02 3.1e-04 0.01 0.02 0.02 0.02 3.1e-03 3.9e-04 1.1e-03 2.7e-04
3 RMTg alternative polyA NM_001106848.1 0.25 0.13 3.2e-03 0 0.06 0.05 0.02 2.6e-01 1.1e-02 2.2e-02 1.1e-01
4 IC gene expression Rnf7 0.14 0.06 2.0e-04 0.09 0.08 0.08 0.09 9.2e-05 2.1e-04 2.1e-04 1.4e-04
5 pVTA isoform ratio XM_063265223.1 0.06 0.04 3.0e-03 0.01 0.02 0.01 0.02 5.6e-02 5.7e-03 7.3e-02 1.7e-02
6 Liver mRNA stability Rnf7 0.06 0.03 1.2e-03 0.04 0.02 0.02 0.03 6.9e-05 2.9e-03 2.1e-03 3.7e-04
7 Brain mRNA stability Rnf7 0.18 0.07 5.6e-09 0.08 0.08 0.1 0.1 4.4e-08 1.5e-07 2.5e-09 1.1e-09
8 IL mRNA stability Rnf7 0.17 0.1 5.5e-03 0.01 0.06 0.04 0.02 2.2e-01 1.4e-02 5.0e-02 8.6e-02
9 Liver gene expression Rnf7 0.04 0.02 1.2e-04 0.01 0.01 0 0.01 1.4e-02 1.9e-02 1.9e-01 5.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.13.4-1.1-1.31.2-0.61.31.80.50.40.2
Area under the delay curve0.20.20.5-0.6-0.30.60.00.60.20.70.20.6
BMI with tail4.816.440.06.35.4-4.93.5-4.2-2.6-2.4-2.9-1.9
BMI without tail4.112.628.15.34.8-4.14.3-4.5-2.4-0.4-0.90.0
Body weight3.917.230.75.55.4-4.94.6-5.5-4.2-1.0-1.1-0.3
Weight adjusted by age1.01.53.71.61.2-0.91.0-1.9-1.9-0.40.2-0.2
Bone surface0.91.64.1-1.2-1.21.7-0.61.02.01.31.01.1
Bone volume0.71.23.4-1.1-1.31.3-0.61.11.80.80.70.6
Breakpoint value in progressive ratio session0.70.81.7-0.5-1.20.9-1.31.11.3-0.1-0.3-0.3
Number of licking bursts0.50.81.90.30.40.51.4-0.40.51.40.91.3
Context. condit. distance diff. score1.21.42.6-0.8-1.20.0-1.51.1-0.1-1.5-1.5-1.6
Locomotion velocity, session 10.90.94.02.00.60.20.30.20.7-1.1-1.1-0.9
Locomotion distance, session 11.82.35.42.31.2-1.40.1-0.5-0.3-2.0-2.1-1.8
Locomotion velocity, session 22.73.210.93.32.5-0.20.5-0.00.7-2.1-2.1-1.5
Locomotion distance, session 23.14.314.73.82.8-1.41.3-1.0-0.3-2.0-2.2-1.6
Locomotion velocity, session 31.11.23.51.51.5-0.21.9-0.50.41.0-0.51.1
Locomotion distance, session 30.10.10.50.60.70.20.1-0.20.20.0-0.30.1
Stereotopy head waving bouts, day 34.75.512.31.21.70.13.5-2.6-1.42.92.13.3
Stereotopy head waving duration, day 33.23.810.41.81.30.13.2-2.1-0.72.21.42.6
Locomotion velocity, session 72.22.45.62.01.4-1.90.7-0.10.1-1.6-2.4-1.9
Locomotion distance, session 70.60.71.61.01.2-0.60.20.10.4-1.3-0.8-1.2
Stereotopy head waving bouts, day 72.02.36.4-1.1-2.52.3-0.91.41.41.40.21.1
Stereotopy head waving duration, day 72.12.56.1-1.1-2.52.0-0.51.11.52.10.61.6
Locomotion velocity, session 81.92.36.41.60.4-0.1-0.41.41.9-1.6-2.5-1.8
Locomotion distance, session 81.42.06.11.10.5-1.2-0.40.3-0.2-2.1-2.5-2.1
Degree of sensitization distance0.60.62.00.10.2-1.0-0.20.40.3-1.3-0.8-1.4
Degree of sensitization stereotypy3.43.79.3-1.2-3.02.1-2.42.42.0-0.3-1.3-0.7
Conditioned locomotion2.32.67.8-0.5-1.81.5-2.02.12.8-0.9-0.4-0.9
Cocaine response after cond. corrected0.81.02.90.61.1-0.81.7-1.1-0.41.00.61.1
Cocaine response after cond. not corrected1.61.94.50.81.6-0.72.1-1.5-1.01.21.21.5
Cocaine response before conditioning0.70.82.40.30.60.00.8-1.0-1.60.81.11.1
Saline control response0.91.22.11.51.1-1.30.7-0.9-0.3-1.2-1.1-1.1
Bone: connectivity density1.32.14.5-1.5-1.91.8-1.31.82.10.30.30.0
Bone: cortical apparent density0.60.81.7-0.5-1.30.6-1.11.00.3-1.0-0.4-1.0
Bone: cortical area1.21.86.11.50.1-1.0-0.20.21.0-1.6-2.5-1.8
Bone: cortical porosity1.71.84.50.6-0.1-0.0-1.21.20.6-2.0-2.1-2.1
Bone: cortical porosity2.93.17.50.1-0.6-0.2-1.91.60.6-2.6-2.6-2.7
Bone: cortical thickness0.61.03.21.20.3-1.20.2-0.20.3-1.0-1.8-1.1
Bone: cortical thickness0.60.72.20.5-0.40.6-0.61.01.5-0.8-0.8-0.7
Bone: cortical tissue density0.50.71.6-0.6-1.30.6-1.11.00.2-1.0-0.3-1.0
Condit. Reinf. active minus inactive responses0.30.41.60.91.0-0.11.3-0.10.20.2-0.2-0.1
Condit. Reinf. active-inactive response ratio1.71.85.62.41.7-0.91.5-0.50.3-1.0-1.5-1.0
Condit. Reinf. active responses0.20.20.90.50.60.10.90.30.60.5-0.10.2
Condit. Reinf. inactive responses0.80.92.1-1.3-0.60.8-0.20.70.51.41.21.1
Incentive salience index mean0.70.92.81.61.7-0.21.3-0.2-0.1-0.4-0.8-0.4
Condit. Reinf. lever presses1.21.64.92.22.0-0.71.0-0.6-0.4-1.1-1.3-0.7
Condit. Reinf. active minus inactive responses0.91.23.00.20.5-0.41.6-0.9-0.41.71.01.6
Condit. Reinf. active-inactive response ratio3.13.610.01.31.8-1.53.2-2.0-1.22.11.12.0
Condit. Reinf. active responses0.50.62.1-0.9-0.5-0.10.3-0.3-0.31.50.91.2
Condit. Reinf. inactive responses1.01.33.9-1.9-1.50.6-2.01.00.3-0.30.0-0.4
Condit. Reinf. lever presses1.31.83.1-0.41.0-1.81.5-1.5-1.51.70.61.4
Condit. Reinf. lever reinforcers received0.30.51.3-0.9-0.4-0.30.3-0.3-0.51.20.60.9
Conditioned reinforcement - actives0.40.72.0-0.00.40.11.0-0.6-0.11.41.01.4
Conditioned reinforcement - inactives0.10.10.5-0.20.1-0.40.0-0.5-0.70.10.10.3
Conditioned locomotion0.30.41.4-0.2-0.51.0-0.31.01.2-0.00.0-0.1
Patch foraging indifference point 0 sec0.10.10.40.40.4-0.60.3-0.10.6-0.0-0.1-0.3
Patch foraging indifference point AUC0.60.91.9-0.9-1.1-0.4-1.40.7-0.2-1.2-0.8-1.1
Delay disc. indifference point, 0s delay0.80.92.0-1.4-1.00.7-0.00.4-0.31.40.91.2
Delay disc. indifference point, 16s delay0.40.41.70.70.7-0.41.3-0.20.30.6-0.40.4
Delay disc. indifference point, 2s delay0.91.02.40.91.5-0.91.4-1.1-0.60.90.11.0
Delay disc. indifference point, 24s delay0.70.81.5-0.9-1.00.8-1.11.20.6-0.9-0.4-0.7
Delay disc. indifference point, 4s delay1.31.44.3-0.8-0.51.00.30.50.62.11.31.9
Delay disc. indifference point, 8s delay0.20.30.9-1.0-0.60.4-0.70.6-0.30.00.10.0
Indifference point function ln k0.91.63.51.51.60.11.9-1.4-0.21.21.11.4
Indifference point function log k0.91.63.51.51.60.11.9-1.4-0.21.21.11.4
Patch foraging total patch changes 0 sec0.10.31.00.60.6-1.00.4-0.40.3-0.1-0.4-0.4
Patch foraging total patch changes 12 sec1.82.35.5-1.0-1.2-0.2-2.01.1-0.5-2.3-1.5-2.3
Patch foraging total patch changes 18 sec0.30.40.9-0.2-0.3-0.7-0.70.40.8-0.9-0.6-1.0
Patch foraging total patch changes 24 sec0.30.51.8-1.3-0.6-1.2-0.5-0.0-0.6-0.1-0.1-0.4
Patch foraging total patch changes 6 sec0.40.52.0-0.5-0.9-0.1-0.50.91.4-0.4-0.5-0.7
Patch foraging time to switch 0 sec1.42.96.1-1.8-2.02.4-1.82.51.80.20.5-0.0
Patch foraging water rate 0 sec1.42.96.31.61.9-2.51.9-2.5-1.70.50.00.6
Patch foraging water rate 12 sec1.63.46.81.82.5-2.12.4-2.6-1.90.70.20.7
Patch foraging water rate 18 sec3.35.010.11.92.6-3.22.3-2.9-3.2-0.4-0.5-0.3
Patch foraging water rate 24 sec1.92.75.91.11.7-2.12.4-2.2-1.41.20.41.0
Patch foraging water rate 6 sec3.44.99.71.52.6-2.82.6-3.1-2.81.20.41.2
Seeking ratio, delayed vs. immediate footshock4.85.910.3-0.9-2.71.6-2.93.23.1-1.8-2.2-2.4
Distance traveled before self-admin0.60.82.40.50.3-0.6-0.40.30.2-1.5-1.2-1.4
Distance traveled after self-admin0.20.20.5-0.2-0.10.7-0.50.4-0.2-0.70.2-0.6
Extensor digitorum longus weight1.45.713.83.73.2-3.02.0-2.3-1.0-1.1-2.2-1.1
Bone: elastic displacement1.41.64.01.30.7-1.30.2-0.6-0.9-2.0-1.6-1.8
Bone: elastic work0.71.02.01.40.6-1.00.5-0.40.1-1.3-1.4-1.2
Bone: endosteal estimation0.20.52.01.41.0-0.00.4-0.21.0-0.2-0.60.0
Bone: endosteal perimeter0.61.33.71.60.7-0.8-0.1-0.00.7-1.4-1.9-1.4
Epididymis fat weight0.41.43.71.71.2-1.90.9-1.2-0.5-0.7-1.0-0.8
Delta time in closed arm before/after self-admin1.31.22.9-1.1-1.10.2-1.71.20.3-1.0-1.3-1.1
Delta time in open arm before/after self-admin0.50.41.2-0.5-0.61.1-0.60.80.6-0.50.3-0.6
Diff in mean of infusions in LGA sessions0.50.61.4-0.5-1.21.1-0.50.70.90.60.00.6
Delay discount exponential model param0.20.20.40.50.1-0.50.0-0.5-0.3-0.6-0.2-0.6
Extinction: sum of active levers before priming1.31.44.0-0.3-0.8-1.0-1.50.1-0.4-1.8-1.2-2.0
Active lever presses in extinction session 61.11.13.2-0.5-1.20.4-1.81.00.2-1.3-0.8-1.3
Bone: final force0.50.81.91.20.7-0.11.4-0.61.20.9-0.11.1
Bone: final moment0.81.33.11.51.1-0.41.8-0.91.21.0-0.01.2
Food consumed during 24 hour testing period0.81.22.2-1.5-0.2-1.20.7-0.9-1.31.31.01.0
Glucose0.50.83.01.11.1-1.70.7-0.8-0.20.0-0.9-0.3
Heart weight1.01.54.60.81.0-1.81.0-1.8-2.1-0.2-0.00.2
Delay discount hyperbolic model param0.20.30.80.4-0.1-0.5-0.2-0.3-0.2-0.9-0.5-0.9
Intermittent access intake day 1-15 change0.10.20.7-0.9-0.70.1-0.60.3-0.5-0.00.1-0.1
Intermittent access intake escalation0.10.20.8-0.9-0.60.1-0.50.2-0.70.00.3-0.0
Intermittent access intake escalation 20.80.91.8-1.3-1.31.2-0.90.90.70.40.60.3
Intermitt. access day 1 inactive lever presses0.20.71.7-0.1-0.70.5-1.30.7-0.2-1.3-0.6-1.1
Intermitt. access day 15 inactive lever presses0.81.75.5-0.7-1.32.3-1.51.81.4-0.4-0.2-0.1
Intermitt. access escalation Index0.91.23.2-0.8-0.70.80.2-0.10.11.71.71.8
Intermittent access day 1 total infusions0.30.41.20.60.7-0.11.1-0.7-0.50.50.40.8
Intermittent access day 15 total infusions0.81.33.10.10.9-0.81.4-1.4-1.81.00.81.1
Intermittent access terminal intake (last 3 days)0.91.22.70.20.9-0.81.4-1.5-1.60.90.71.1
Intermittent access total infusions0.60.81.60.40.9-0.71.2-1.2-1.20.50.30.8
Intermittent access day 1 locomotion0.20.31.11.00.80.10.5-0.2-0.1-0.6-0.3-0.4
Intermittent access day 15 total locomotion0.10.20.60.60.4-0.00.20.10.0-0.4-0.8-0.4
Intermittent access total locomotion0.10.20.50.50.20.1-0.10.0-0.2-0.7-0.4-0.6
Intermittent access standard deviation0.00.10.30.40.10.50.20.10.10.2-0.50.1
Left kidney weight1.67.522.74.84.0-2.42.2-2.5-1.0-2.3-1.7-1.6
Right kidney weight1.88.117.54.23.9-3.32.1-3.0-2.1-2.3-1.7-1.6
Cocaine induced anxiety0.40.51.0-0.9-0.81.0-1.00.80.40.30.50.2
Post-drug Anxiety0.30.31.4-1.2-0.7-0.1-0.60.1-0.50.60.30.4
Baseline Anxiety0.60.72.5-0.20.3-1.60.1-0.6-1.4-0.5-1.0-0.7
Tail length1.03.97.51.01.8-0.72.7-2.7-1.61.72.42.2
Length with tail0.83.37.31.31.8-1.12.3-2.7-2.50.81.31.4
Length without tail0.82.76.41.61.8-1.32.1-2.5-2.30.50.30.9
Times rat made contact with spout0.81.03.30.00.6-1.40.9-1.2-1.8-0.2-0.7-0.4
Lifetime Intake0.60.81.90.61.0-0.51.4-1.1-0.90.70.40.9
Liver weight, left0.81.32.51.21.3-1.51.1-1.6-1.4-0.6-0.5-0.1
Liver weight, right0.50.92.81.71.4-0.91.0-1.1-0.5-0.3-0.20.1
Locomotor activity1.52.34.61.02.0-2.11.8-2.1-1.60.00.70.5
Locomotor testing distance0.40.71.50.51.1-1.21.2-1.1-0.60.20.60.4
Locomotor testing rearing0.40.82.10.80.9-1.41.0-1.3-1.1-0.3-0.1-0.1
Locomotion in novel chamber1.51.94.0-1.2-1.01.30.11.32.02.01.11.4
Locomotion in novel chamber post-restriction0.50.92.5-0.9-0.40.50.2-0.2-0.31.51.61.4
Fecal boli incidents, locomotor time 10.81.24.50.61.5-2.11.0-1.1-1.10.3-0.6-0.1
Change in fecal boli incidents, locomotor task0.60.62.41.50.50.30.2-0.10.7-1.0-0.2-0.8
Time >=10cm from walls, locomotor time 10.30.41.30.4-0.00.3-0.60.4-0.2-1.1-0.8-0.7
Bouts of movement, locomotor time 10.70.71.80.70.80.31.2-0.60.31.10.71.3
Total resting periods, locomotor time 10.80.92.21.01.00.21.5-0.80.11.00.61.2
Rest time, locomotor task time 10.81.02.41.41.3-0.90.5-0.7-0.6-0.8-1.5-0.6
Distance moved, locomotor task time 10.20.40.9-0.4-0.50.60.00.61.00.60.80.4
Vertical activity count, locomotor time 10.40.92.3-1.5-1.20.5-1.01.11.00.40.40.1
Time >=10cm from walls, locomotor time 20.60.82.1-0.2-0.71.3-0.91.41.3-0.2-0.8-0.2
Bouts of movement, locomotor time 20.30.50.90.50.2-0.8-0.4-0.5-1.0-0.8-0.9-0.7
Total resting periods, locomotor time 20.30.61.30.60.4-0.9-0.2-0.7-1.2-0.9-0.8-0.7
Rest time, locomotor task time 20.10.10.30.10.3-0.5-0.2-0.0-0.3-0.5-0.5-0.5
Distance moved, locomotor task time 20.81.02.8-0.3-0.41.50.11.11.71.10.41.0
Vertical activity count, locomotor time 20.70.91.9-1.2-1.41.0-1.41.21.00.2-0.1-0.1
Light reinforcement 10.81.95.6-0.51.3-1.41.5-1.6-2.40.90.81.2
Light reinforcement 20.50.82.11.01.40.31.5-0.7-0.10.70.21.1
Bone: marrow area0.30.62.41.51.1-0.10.4-0.21.0-0.3-0.6-0.0
Bone: maximum diameter1.73.29.62.10.7-1.4-0.50.21.2-2.2-3.1-2.3
Bone: maximum force0.20.41.61.00.40.20.20.21.3-0.3-0.7-0.1
Bone: maximum moment0.30.51.81.30.8-0.10.6-0.21.2-0.2-0.70.0
Mean time between licks in bursts0.30.61.20.6-0.50.9-0.80.80.7-0.9-1.1-0.7
Mean num. licks in bursts1.11.83.9-0.10.3-1.8-0.5-0.6-2.0-1.7-1.5-1.7
Cd content in liver1.11.23.2-1.8-1.30.8-1.71.30.5-0.4-0.2-0.7
Co content in liver0.50.61.5-0.1-0.1-0.1-0.90.80.2-1.1-1.2-1.0
Cu content in liver0.70.92.7-0.8-0.30.80.80.20.11.60.91.5
Fe content in liver0.80.92.70.20.20.31.3-0.60.51.60.81.6
K content in liver0.80.72.31.51.40.10.60.31.2-0.2-0.6-0.1
Mg content in liver0.20.20.70.60.50.20.10.30.8-0.2-0.4-0.2
Mn content in liver1.11.23.51.41.0-0.70.2-0.2-0.1-1.6-1.9-1.3
Na content in liver0.60.63.00.4-0.20.9-0.21.21.70.1-0.4-0.1
Rb content in liver0.20.31.40.2-0.0-0.70.5-0.6-1.20.3-0.10.1
Se content in liver0.50.61.3-0.9-0.10.80.40.20.31.21.11.1
Sr content in liver0.20.20.4-0.4-0.50.5-0.10.50.60.5-0.00.5
Zn content in liver0.30.31.0-0.9-0.20.4-0.30.1-0.50.51.00.4
Bone: minimum diameter0.10.20.70.4-0.40.1-0.10.10.8-0.3-0.8-0.4
Time in familiar zone, hab. session 13.43.36.4-1.6-2.02.4-0.10.70.82.32.52.1
Time in novel zone, hab. session 13.23.26.11.62.1-2.50.2-1.2-1.4-2.1-1.9-2.0
Total zone transitions, hab. session 11.62.36.22.20.8-1.30.00.00.1-1.9-2.5-1.9
Total locomotion distance, hab. session 11.21.74.12.01.0-1.30.2-0.30.2-1.7-1.7-1.7
Locomotion velocity, hab. session 11.52.25.31.90.6-1.3-0.10.20.5-2.0-2.3-2.0
Time in familiar zone, hab. session 21.31.43.8-1.9-2.0-0.3-1.50.1-1.4-0.40.4-0.6
Time in novel zone, hab. session 21.61.65.62.41.9-0.51.3-0.31.2-0.5-1.2-0.3
Total zone transitions, hab. session 21.82.34.72.21.8-1.80.7-0.7-0.4-1.6-2.0-1.3
Total locomotion distance, hab. session 21.01.32.41.51.5-1.50.7-0.7-0.4-1.4-1.1-1.0
Locomotion velocity, hab. session 21.01.32.51.61.5-1.30.6-0.5-0.2-1.4-1.2-1.1
Novel to familiar place preference ratio0.60.71.60.1-0.6-0.3-1.30.50.6-1.0-0.8-1.3
Novelty place preference0.40.41.20.5-0.2-0.5-0.80.10.4-0.9-0.8-1.1
Time in novel zone, NPP test0.50.51.30.9-0.0-0.7-0.5-0.20.2-0.9-0.9-1.1
Total zone transitions, NPP test4.66.615.33.93.5-2.71.8-1.8-1.6-2.4-2.5-2.1
Total locomotion distance, NPP test3.14.210.93.32.8-2.31.9-1.7-0.9-1.6-1.7-1.2
Locomotion velocity, NPP test2.43.48.02.82.7-2.11.6-1.3-0.7-1.5-1.6-1.2
Intraocular pressure1.01.43.21.31.8-1.41.4-1.6-1.20.0-0.20.3
Delta distance traveled before/after self-admin0.40.41.1-0.9-0.70.8-0.70.2-0.20.31.00.3
Delta ambulatory time before/after self-admin0.30.41.9-0.4-0.30.7-0.2-0.10.10.71.40.7
Parametrial fat weight0.81.93.40.81.4-1.71.8-1.8-1.80.90.31.0
Pavlov. Cond. lever latency1.21.53.3-1.8-1.8-0.1-0.3-0.4-0.91.61.51.3
Pavlov. Cond. magazine entry latency1.31.73.61.81.7-0.40.6-0.1-0.1-1.8-1.9-1.4
Pavlov. Cond. change in total contacts0.40.51.10.61.0-0.00.20.30.0-1.0-1.0-0.8
Pavlov. Cond. index score1.41.73.81.71.6-0.10.20.40.5-1.9-1.9-1.6
Pavlov. Cond. latency score1.51.93.61.91.9-0.40.40.10.2-1.9-1.8-1.5
Pavlov. Cond. lever contacts1.51.84.21.71.40.3-0.10.61.0-2.0-1.8-1.6
Pavlov. Cond. magazine entry number0.70.81.9-1.1-0.9-0.4-0.1-0.5-0.51.41.41.0
Pavlov. Cond. intertrial magazine entries1.41.63.5-1.8-1.01.2-0.20.40.61.91.81.3
Pavlov. Cond. lever-magazine prob. diff.1.31.73.81.51.50.20.00.70.6-2.0-1.9-1.6
Pavlov. Cond. response bias0.81.01.81.31.10.70.20.71.0-1.2-1.3-0.8
Pavlov. Cond. lever latency1.11.45.3-0.2-1.42.3-0.91.21.70.20.60.5
Pavlov. Cond. magazine entry latency1.61.94.11.01.4-1.61.1-1.3-2.0-1.4-1.1-1.2
Pavlov. Cond. change in total contacts2.54.011.90.92.0-3.51.7-2.3-3.1-0.5-0.8-0.6
Pavlov. Cond. index score1.21.64.30.61.5-1.81.3-1.4-2.1-0.5-0.5-0.6
Pavlov. Cond. latency score1.31.74.10.61.5-1.91.3-1.4-2.0-0.6-0.6-0.6
Pavlov. Cond. lever contacts1.21.74.90.61.7-2.21.0-1.3-1.8-0.4-0.7-0.7
Pavlov. Cond. magazine entry number0.70.93.0-0.6-0.90.9-0.90.81.70.70.80.7
Pavlov. Cond. intertrial magazine entries3.75.611.9-2.3-3.12.8-2.02.53.41.51.41.1
Pavlov. Cond. lever-magazine prob. diff.1.31.75.00.51.4-1.91.3-1.4-2.2-0.6-0.6-0.6
Pavlov. Cond. response bias1.41.95.10.41.5-2.30.9-1.1-2.0-0.8-1.2-1.1
Time in closed arm before self-admin1.21.52.31.51.30.01.5-1.20.21.31.41.5
Time in closed arm after self-admin0.10.10.60.80.5-0.2-0.1-0.40.00.2-0.10.3
Time in open arm before self-admin0.20.30.7-0.8-0.4-0.9-0.10.0-0.70.2-0.5-0.2
Time in open arm after self-admin1.71.83.8-1.9-1.81.3-1.61.80.6-0.8-0.2-1.1
Bone: periosteal estimation0.61.33.61.80.7-0.60.00.11.4-1.0-1.9-1.0
Bone: periosteal perimeter1.42.47.91.1-0.2-0.9-1.00.61.0-2.1-2.8-2.2
Bone: post-yield work0.30.40.9-0.3-0.00.8-0.40.40.60.90.31.0
Progressive ratio test 1 active lever presses0.30.30.60.70.5-0.20.8-0.40.30.70.50.6
Progressive ratio test 1 breakpoint0.20.20.40.70.5-0.20.6-0.30.50.50.40.5
Progressive ratio test 1 inactive lever presses0.30.50.9-0.7-1.00.8-0.60.50.30.80.90.6
Progressive ratio test 2 active lever presses0.60.71.80.60.8-0.81.3-1.1-0.60.70.10.8
Progressive ratio test 2 breakpoint0.50.61.60.40.7-0.91.3-1.0-0.60.80.20.8
Progressive ratio test 2 inactive lever presses0.30.41.0-0.4-0.20.30.4-0.6-0.80.90.91.0
Incentive Sensitization - Responses0.60.82.20.40.8-0.91.3-1.2-1.50.5-0.40.6
Incentive Sensitization - Breakpoint0.60.81.90.40.8-0.91.3-1.1-1.40.4-0.40.6
Sum of active levers in priming session hrs 5-61.00.92.5-0.2-0.5-0.5-1.10.2-0.2-1.6-1.3-1.4
Progressive ratio0.91.53.92.01.2-0.80.2-0.20.9-1.2-1.8-1.2
Food seeking constrained by brief footshock0.50.61.30.3-0.20.8-0.61.11.0-0.8-1.2-0.6
Seeking ratio, punishment vs. effort0.30.51.2-1.1-0.81.0-0.40.7-0.30.40.50.6
Retroperitoneal fat weight1.14.510.32.52.8-3.22.3-2.4-1.7-0.5-1.1-0.4
Reaction time number correct0.10.10.3-0.2-0.2-0.5-0.2-0.5-0.3-0.00.4-0.0
Reaction time mean minus median0.10.41.1-0.20.10.1-0.70.1-0.8-1.1-0.3-0.9
Reaction time mean minus median AUC0.20.41.50.20.7-0.6-0.1-0.5-1.2-0.8-0.4-0.7
Reaction time num false alarms0.30.41.2-1.1-0.40.5-0.10.30.40.51.00.5
Reaction time num false alarms AUC0.50.72.2-1.5-0.81.0-0.40.70.60.51.10.5
Reaction time trials correct on left0.10.10.3-0.2-0.2-0.5-0.2-0.5-0.3-0.00.4-0.0
Reaction time trials on left0.10.10.3-0.2-0.2-0.6-0.2-0.5-0.4-0.10.4-0.1
Reaction time mean0.20.32.5-0.50.10.2-0.2-0.2-1.6-0.4-0.2-0.2
Reaction time mean AUC0.20.31.7-0.7-0.00.3-0.0-0.1-1.3-0.00.10.1
Median of all reaction times0.20.32.1-0.7-0.00.2-0.0-0.1-1.40.1-0.10.2
Reaction time omissions0.30.41.3-1.1-0.5-0.2-0.90.7-0.4-0.5-0.1-0.8
Reaction time false alarm rate0.30.51.1-0.9-0.31.00.00.60.60.70.90.6
Reaction time premature initiation rate0.40.61.8-0.3-0.31.30.20.20.40.80.81.3
Reaction time premature initiations0.20.30.9-0.4-0.41.0-0.10.20.20.40.60.8
Std. dev. reaction times0.20.30.8-0.5-0.0-0.0-0.70.2-0.9-0.7-0.3-0.7
Reaction time trials completed0.10.10.3-0.2-0.2-0.6-0.2-0.5-0.4-0.10.4-0.1
Reaction time trials AUC0.10.10.2-0.5-0.3-0.5-0.4-0.4-0.4-0.00.4-0.0
Run reversals in cocaine runway, females0.40.41.51.20.90.40.7-0.10.60.20.50.4
Run reversals in cocaine runway, males0.40.41.31.10.60.30.6-0.5-0.2-0.8-0.8-0.3
Latency to leave start box in cocaine runway1.41.53.7-1.9-1.61.6-1.21.30.60.60.80.6
Latency to leave start box in cocaine runway, F0.81.02.6-1.6-1.30.8-0.70.4-0.40.71.30.8
Latency to leave start box in cocaine runway, M1.21.13.0-0.8-0.71.7-0.91.51.50.50.10.5
Std. dev. time between licks in bursts1.72.45.8-0.3-1.61.2-1.72.22.4-0.9-1.3-1.0
Total sessions with >9 infusions0.20.20.60.10.30.10.6-0.10.40.80.60.7
Short access day 1 total inactive lever presses1.01.35.10.4-0.62.3-1.11.51.4-0.70.1-0.4
Short access day 10 total inactive lever presses0.51.21.80.4-0.80.7-1.31.01.3-1.3-1.3-1.3
Short access day 1 total infusions0.30.41.0-0.7-0.71.0-0.30.60.70.60.70.6
Short access day 10 total infusions0.40.51.60.60.8-0.80.8-0.9-1.3-0.0-0.00.2
Short access total infusions0.10.20.50.20.30.10.5-0.10.30.60.40.7
Short access day 1 locomotion0.10.20.7-0.2-0.40.2-0.40.50.80.30.30.2
Short access day 10 total locomotion0.91.73.50.3-0.80.3-1.61.20.9-1.8-1.7-1.9
Short access total locomotion0.30.40.80.70.2-0.4-0.30.20.5-0.9-0.8-0.9
One hour access (0.3 mA shock)0.80.91.8-0.60.1-0.30.8-1.0-1.21.31.31.2
Compulsive drug intake1.72.05.6-2.4-1.70.5-0.80.50.11.62.01.2
One hour access (shock baseline)0.40.61.20.30.60.11.1-1.0-1.10.80.41.1
Social response proportion0.30.31.0-0.7-0.41.0-0.80.80.2-0.20.3-0.1
Social responses0.20.20.9-0.8-0.4-0.1-0.1-0.1-0.90.30.10.5
Social time0.40.52.2-1.5-0.5-0.3-0.3-0.2-1.40.10.20.2
Soleus weight1.54.610.03.03.1-2.53.2-2.3-0.10.6-0.70.5
Bone: stiffness0.30.51.9-0.0-0.21.0-0.50.81.40.1-0.40.1
Tibialis anterior weight1.44.613.33.03.6-2.52.5-2.4-0.7-0.0-0.40.1
Time to tail flick, vehicle, before self-admin0.10.10.5-0.5-0.2-0.7-0.0-0.2-0.50.2-0.20.0
Time to tail flick, vehicle, after self-admin0.71.03.21.00.8-0.4-0.3-0.3-1.0-1.8-0.9-1.4
Time to tail flick, test, before self-admin0.30.30.7-0.3-0.40.70.10.60.60.70.00.8
Time to tail flick, test, after self-admin1.31.42.91.11.2-1.31.7-1.5-0.71.0-0.01.1
Delta time to tail flick, vehicle, before/after SA0.60.62.20.90.50.5-0.50.50.3-1.5-0.6-1.1
Delta time to tail flick, test, before/after SA1.21.22.80.81.2-1.61.5-1.7-1.10.50.30.5
Tibia length2.46.514.03.13.2-0.83.7-2.7-0.52.41.72.8
Ambulatory time before self-admin0.50.71.90.50.3-0.8-0.40.30.2-1.4-1.4-1.4
Ambulatory time after self-admin0.30.30.7-0.1-0.20.5-0.80.60.4-0.80.2-0.7
Bone: tissue strength3.13.15.40.41.7-1.82.1-2.3-2.21.61.11.8
Total heroin consumption0.70.83.60.30.8-0.70.8-1.3-1.9-0.1-0.20.2
Bone: trabecular number1.72.75.6-1.6-2.22.4-1.52.12.10.40.40.1
Bone: trabecular spacing0.60.83.3-0.20.2-1.80.5-1.0-1.40.40.00.3
Bone: trabecular thickness0.30.41.61.10.30.20.6-0.21.30.10.50.3
Bone: trabecular tissue density1.11.63.61.71.4-1.1-0.1-0.4-0.1-1.9-1.3-1.7
Water consumed over 24 hours0.20.31.30.10.4-0.31.1-0.7-0.10.80.20.4
Number of responses in last shaping day0.10.10.20.3-0.1-0.0-0.40.20.3-0.2-0.3-0.2