Apoh

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Apoh 0.07 0.04 1.2e-07 0.07 0.08 0.08 0.09 2.6e-08 9.7e-09 7.3e-09 1.4e-09
2 Adipose gene expression Apoh 0.03 0.02 1.1e-03 0.01 0.01 0.01 0.01 1.4e-02 9.0e-03 6.7e-03 1.1e-02
3 NAcc gene expression Apoh 0.24 0.09 0.0e+00 0.17 0.22 0.21 0.21 3.3e-19 1.6e-24 9.4e-24 1.3e-23
4 Liver gene expression Apoh 0.17 0.08 5.6e-17 0.09 0.13 0.13 0.12 3.2e-10 2.1e-14 7.5e-14 1.5e-13
5 Brain gene expression Apoh 0.06 0.04 4.7e-03 0.01 0.02 0.01 0.01 4.9e-02 2.4e-03 2.6e-02 2.7e-02
6 Liver mRNA stability Apoh 0.25 0.1 0.0e+00 0.25 0.24 0.25 0.26 5.6e-28 1.5e-26 1.0e-27 3.5e-28

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density0.20.31.3-0.10.00.3-0.60.1-1.1
Area under the delay curve0.10.10.50.0-0.00.40.00.7-0.0
BMI with tail3.210.333.01.9-2.1-0.44.5-0.25.7
BMI without tail2.45.013.11.5-1.80.13.3-0.33.6
Body weight4.217.735.74.0-4.02.06.01.95.6
Weight adjusted by age0.30.31.3-0.20.1-0.50.60.11.2
Bone surface1.01.83.31.3-1.31.8-0.11.3-1.5
Bone volume1.32.24.01.6-1.62.00.41.7-0.9
Breakpoint value in progressive ratio session1.21.32.7-1.11.0-1.60.1-1.60.7
Number of licking bursts0.70.81.51.0-0.91.10.61.20.2
Context. condit. distance diff. score0.20.20.40.5-0.50.30.60.50.4
Locomotion velocity, session 10.00.00.1-0.00.0-0.10.1-0.2-0.1
Locomotion distance, session 10.10.10.2-0.20.2-0.40.1-0.40.3
Locomotion velocity, session 21.21.53.0-1.21.2-1.2-0.8-1.7-0.7
Locomotion distance, session 21.11.53.2-1.21.3-1.5-0.6-1.80.0
Locomotion velocity, session 31.31.53.3-1.31.0-1.8-0.4-1.60.6
Locomotion distance, session 30.10.10.10.1-0.20.1-0.30.3-0.3
Stereotopy head waving bouts, day 36.07.19.9-3.13.1-2.6-2.6-2.5-1.7
Stereotopy head waving duration, day 32.83.45.0-2.22.1-1.7-1.9-1.6-1.3
Locomotion velocity, session 70.40.40.9-0.70.6-1.0-0.2-0.90.3
Locomotion distance, session 70.60.71.01.0-1.00.90.51.00.2
Stereotopy head waving bouts, day 73.23.65.2-2.22.1-2.3-1.5-2.2-0.5
Stereotopy head waving duration, day 75.26.38.5-2.92.8-2.7-2.4-2.6-1.3
Locomotion velocity, session 80.00.10.20.0-0.30.1-0.20.0-0.5
Locomotion distance, session 80.10.10.4-0.30.2-0.50.1-0.70.1
Degree of sensitization distance0.20.20.40.4-0.40.60.40.5-0.0
Degree of sensitization stereotypy1.71.93.5-1.51.4-1.9-0.7-1.80.3
Conditioned locomotion0.10.20.2-0.50.4-0.3-0.5-0.4-0.4
Cocaine response after cond. corrected0.50.61.50.7-0.61.00.11.2-0.2
Cocaine response after cond. not corrected0.50.61.60.7-0.70.90.01.3-0.3
Cocaine response before conditioning0.10.10.2-0.20.2-0.2-0.5-0.1-0.5
Saline control response1.62.16.60.6-0.8-0.52.1-0.72.6
Bone: connectivity density1.42.24.3-1.41.3-0.7-1.8-1.2-2.1
Bone: cortical apparent density2.33.04.6-2.22.2-2.1-1.1-1.80.2
Bone: cortical area0.81.32.31.2-1.30.81.50.51.0
Bone: cortical porosity1.51.73.01.7-1.71.41.01.00.1
Bone: cortical porosity2.62.84.52.0-2.11.71.61.50.8
Bone: cortical thickness2.84.58.3-1.81.6-2.90.5-2.72.3
Bone: cortical thickness2.63.05.9-1.91.7-2.2-0.5-2.40.5
Bone: cortical tissue density2.22.94.5-2.12.1-2.1-1.1-1.80.2
Condit. Reinf. active minus inactive responses3.64.05.62.4-2.32.41.62.20.3
Condit. Reinf. active-inactive response ratio1.21.32.31.2-1.11.50.41.5-0.5
Condit. Reinf. active responses2.53.14.72.1-2.22.01.51.70.4
Condit. Reinf. inactive responses0.20.20.50.6-0.50.30.70.00.3
Incentive salience index mean1.41.72.71.6-1.71.41.21.20.6
Condit. Reinf. lever presses0.40.51.60.3-0.5-0.30.8-0.41.3
Condit. Reinf. active minus inactive responses2.63.25.52.1-2.02.30.91.9-0.6
Condit. Reinf. active-inactive response ratio3.23.45.52.2-2.22.40.82.1-0.5
Condit. Reinf. active responses2.43.35.62.2-2.12.41.21.8-0.5
Condit. Reinf. inactive responses0.10.10.30.00.00.00.3-0.5-0.3
Condit. Reinf. lever presses2.02.74.32.1-2.01.61.81.10.8
Condit. Reinf. lever reinforcers received2.43.45.72.3-2.12.41.31.8-0.4
Conditioned reinforcement - actives1.91.93.5-1.51.4-0.6-1.5-1.0-1.9
Conditioned reinforcement - inactives1.01.11.41.2-1.21.11.01.10.5
Conditioned locomotion1.21.53.11.2-1.21.80.81.5-0.3
Patch foraging indifference point 0 sec3.45.58.42.6-2.62.42.91.81.3
Patch foraging indifference point AUC0.40.50.80.9-0.60.80.60.80.3
Delay disc. indifference point, 0s delay0.00.00.10.10.00.0-0.30.4-0.2
Delay disc. indifference point, 16s delay0.10.10.2-0.0-0.10.30.40.40.5
Delay disc. indifference point, 2s delay0.40.41.3-0.30.40.4-0.70.3-1.1
Delay disc. indifference point, 24s delay1.31.31.71.0-1.11.11.31.11.2
Delay disc. indifference point, 4s delay0.30.30.6-0.50.6-0.3-0.8-0.0-0.7
Delay disc. indifference point, 8s delay0.20.20.4-0.60.6-0.4-0.3-0.00.2
Indifference point function ln k1.21.72.3-1.51.5-1.0-1.3-1.1-1.3
Indifference point function log k1.21.72.3-1.51.5-1.0-1.3-1.1-1.3
Patch foraging total patch changes 0 sec3.14.97.62.5-2.52.32.71.61.2
Patch foraging total patch changes 12 sec3.64.76.82.6-2.42.52.12.00.8
Patch foraging total patch changes 18 sec2.12.74.81.9-1.61.22.21.01.7
Patch foraging total patch changes 24 sec3.64.46.02.5-2.32.12.41.91.2
Patch foraging total patch changes 6 sec6.08.912.03.5-3.33.03.42.61.8
Patch foraging time to switch 0 sec0.10.20.40.4-0.40.10.30.30.7
Patch foraging water rate 0 sec0.40.61.20.8-0.91.10.90.6-0.1
Patch foraging water rate 12 sec0.10.10.30.0-0.3-0.10.6-0.10.6
Patch foraging water rate 18 sec0.50.71.6-1.10.8-1.0-0.1-1.30.0
Patch foraging water rate 24 sec0.81.11.8-1.31.1-0.9-1.1-0.9-0.8
Patch foraging water rate 6 sec0.81.11.8-1.30.9-1.2-0.7-1.3-0.4
Seeking ratio, delayed vs. immediate footshock0.60.70.90.9-0.90.70.91.00.7
Distance traveled before self-admin0.70.71.2-0.90.8-0.4-1.1-0.3-1.1
Distance traveled after self-admin0.30.40.6-0.80.7-0.7-0.5-0.6-0.2
Extensor digitorum longus weight0.83.213.10.6-1.0-0.72.10.13.6
Bone: elastic displacement1.31.52.3-1.41.5-1.5-0.7-1.4-0.1
Bone: elastic work0.30.40.9-0.30.4-0.70.6-0.80.9
Bone: endosteal estimation10.122.137.95.6-5.26.22.75.3-1.0
Bone: endosteal perimeter10.421.537.15.4-5.06.12.65.4-0.8
Epididymis fat weight3.99.221.02.5-2.51.04.31.34.6
Delta time in closed arm before/after self-admin0.50.51.5-0.20.30.5-0.80.6-1.2
Delta time in open arm before/after self-admin1.91.92.3-1.51.5-1.3-1.5-1.3-1.0
Diff in mean of infusions in LGA sessions0.60.72.5-0.20.0-0.90.8-0.61.6
Delay discount exponential model param0.30.41.1-0.40.4-0.8-0.2-1.10.0
Extinction: sum of active levers before priming0.30.30.4-0.50.5-0.70.2-0.60.4
Active lever presses in extinction session 60.20.20.50.1-0.0-0.30.7-0.70.4
Bone: final force0.50.81.41.1-1.01.20.70.80.0
Bone: final moment0.40.71.31.0-0.91.10.60.7-0.1
Food consumed during 24 hour testing period1.31.63.4-0.30.5-1.11.4-1.61.8
Glucose0.00.00.1-0.20.1-0.2-0.20.20.3
Heart weight3.04.35.72.2-2.41.92.02.31.3
Delay discount hyperbolic model param0.20.20.7-0.10.1-0.60.1-0.90.2
Intermittent access intake day 1-15 change3.43.34.82.1-2.22.01.42.10.6
Intermittent access intake escalation3.73.65.32.2-2.22.11.42.30.6
Intermittent access intake escalation 24.44.35.92.3-2.42.41.72.40.6
Intermitt. access day 1 inactive lever presses2.22.43.41.8-1.81.21.81.01.3
Intermitt. access day 15 inactive lever presses1.41.63.01.2-1.30.81.70.91.4
Intermitt. access escalation Index0.90.81.7-0.50.8-0.5-1.3-0.6-1.2
Intermittent access day 1 total infusions0.00.00.00.0-0.10.10.2-0.1-0.0
Intermittent access day 15 total infusions3.43.85.42.2-2.32.21.72.10.7
Intermittent access terminal intake (last 3 days)3.43.75.52.2-2.22.41.62.00.5
Intermittent access total infusions1.71.92.81.5-1.61.71.31.30.4
Intermittent access day 1 locomotion3.53.75.22.2-2.31.92.01.71.4
Intermittent access day 15 total locomotion4.75.07.32.6-2.72.52.02.20.9
Intermittent access total locomotion7.38.311.53.2-3.43.13.12.61.7
Intermittent access standard deviation5.45.78.02.7-2.82.42.02.61.4
Left kidney weight0.61.73.91.1-1.00.42.00.71.9
Right kidney weight1.33.76.92.0-1.91.22.61.42.1
Cocaine induced anxiety0.80.91.3-1.11.0-0.6-1.0-0.7-1.1
Post-drug Anxiety0.91.01.6-1.21.1-0.5-1.3-0.3-1.2
Baseline Anxiety1.11.21.8-1.31.3-1.3-1.0-1.0-0.2
Tail length0.92.73.91.9-1.92.01.61.50.3
Length with tail2.17.69.83.1-3.03.12.72.91.1
Length without tail0.71.62.21.4-1.21.21.31.50.8
Times rat made contact with spout0.50.51.20.8-0.70.51.10.20.8
Lifetime Intake1.21.31.91.3-1.41.41.21.00.4
Liver weight, left0.81.22.3-1.11.1-0.6-1.3-0.8-1.5
Liver weight, right1.01.62.5-1.51.6-1.3-1.0-1.4-0.6
Locomotor activity1.11.74.41.0-1.00.22.1-0.22.0
Locomotor testing distance0.61.12.90.5-0.4-0.21.7-0.61.7
Locomotor testing rearing0.91.44.00.4-0.4-0.61.7-1.02.0
Locomotion in novel chamber0.20.20.5-0.70.7-0.5-0.3-0.3-0.1
Locomotion in novel chamber post-restriction0.10.10.50.2-0.10.70.20.5-0.2
Fecal boli incidents, locomotor time 10.91.02.80.8-0.91.20.01.7-0.1
Change in fecal boli incidents, locomotor task0.50.51.3-0.50.7-0.1-0.7-0.4-1.1
Time >=10cm from walls, locomotor time 10.10.10.4-0.00.3-0.3-0.6-0.1-0.3
Bouts of movement, locomotor time 10.70.82.00.7-0.80.11.20.31.4
Total resting periods, locomotor time 10.60.71.40.8-0.90.31.00.61.2
Rest time, locomotor task time 10.10.10.2-0.20.1-0.1-0.50.2-0.3
Distance moved, locomotor task time 10.40.40.9-0.00.2-0.70.5-1.00.9
Vertical activity count, locomotor time 10.20.20.40.3-0.2-0.20.6-0.40.7
Time >=10cm from walls, locomotor time 21.61.63.4-1.00.9-1.80.3-1.81.1
Bouts of movement, locomotor time 21.41.65.60.1-0.2-0.81.7-0.52.4
Total resting periods, locomotor time 21.11.24.30.2-0.3-0.51.5-0.22.1
Rest time, locomotor task time 22.42.76.0-1.61.6-0.6-2.50.1-2.2
Distance moved, locomotor task time 22.02.34.7-0.30.3-1.81.2-2.22.1
Vertical activity count, locomotor time 22.02.15.50.9-1.0-0.32.1-1.02.3
Light reinforcement 11.01.83.6-1.11.0-1.80.2-1.91.2
Light reinforcement 20.10.10.2-0.40.5-0.3-0.1-0.00.3
Bone: marrow area9.821.236.65.5-5.16.02.65.2-1.0
Bone: maximum diameter3.05.510.12.6-2.53.20.92.8-1.1
Bone: maximum force1.52.53.81.9-1.81.91.41.50.4
Bone: maximum moment1.42.43.61.9-1.81.91.31.50.3
Mean time between licks in bursts2.53.54.61.9-2.01.32.21.62.0
Mean num. licks in bursts0.30.30.8-0.50.4-0.70.1-0.90.4
Cd content in liver0.60.71.7-0.90.5-0.5-1.3-0.2-1.0
Co content in liver0.20.20.60.4-0.50.40.20.80.3
Cu content in liver0.10.20.6-0.10.20.3-0.50.2-0.7
Fe content in liver0.00.10.1-0.20.0-0.2-0.3-0.3-0.3
K content in liver1.51.44.0-0.81.10.2-1.60.1-2.0
Mg content in liver3.83.96.6-2.02.2-0.8-2.5-1.1-2.6
Mn content in liver3.53.96.8-2.02.2-0.9-2.4-1.2-2.6
Na content in liver1.11.22.2-1.11.2-0.4-1.5-0.3-1.4
Rb content in liver1.72.14.1-1.31.4-0.5-2.0-0.6-2.0
Se content in liver1.01.22.4-1.31.2-0.8-1.5-0.4-1.0
Sr content in liver1.00.91.40.9-1.10.61.20.71.2
Zn content in liver0.80.92.1-0.80.8-0.0-1.50.2-1.4
Bone: minimum diameter8.616.125.14.8-4.55.03.14.40.4
Time in familiar zone, hab. session 12.52.43.61.8-1.81.90.91.90.0
Time in novel zone, hab. session 11.61.52.7-1.41.3-1.6-0.6-1.60.1
Total zone transitions, hab. session 10.71.13.20.3-0.4-0.61.3-0.81.8
Total locomotion distance, hab. session 10.71.02.3-0.30.2-1.10.9-1.51.3
Locomotion velocity, hab. session 10.60.92.1-0.30.3-1.10.8-1.51.2
Time in familiar zone, hab. session 21.41.42.31.5-1.31.40.91.20.2
Time in novel zone, hab. session 22.82.84.1-2.01.9-1.5-1.6-1.6-1.1
Total zone transitions, hab. session 21.21.54.2-0.30.2-1.31.1-1.42.0
Total locomotion distance, hab. session 21.41.94.1-0.80.8-1.60.8-2.01.6
Locomotion velocity, hab. session 21.62.24.8-1.11.1-1.80.5-2.21.4
Novel to familiar place preference ratio3.13.24.52.0-2.12.11.32.00.3
Novelty place preference2.12.13.01.7-1.71.71.11.60.3
Time in novel zone, NPP test1.61.72.41.5-1.51.51.01.40.2
Total zone transitions, NPP test1.21.73.7-1.21.2-1.70.1-1.90.8
Total locomotion distance, NPP test1.82.56.4-1.51.6-1.9-0.1-2.50.3
Locomotion velocity, NPP test1.31.94.5-1.21.3-1.70.2-2.10.8
Intraocular pressure0.20.30.70.4-0.60.00.70.00.9
Delta distance traveled before/after self-admin1.21.32.9-1.01.0-1.5-0.1-1.70.7
Delta ambulatory time before/after self-admin0.40.41.0-0.60.7-0.7-0.1-1.00.1
Parametrial fat weight0.81.54.2-1.11.1-0.1-1.4-0.5-2.0
Pavlov. Cond. lever latency1.31.73.8-1.11.2-0.3-1.8-0.2-2.0
Pavlov. Cond. magazine entry latency1.51.92.81.6-1.71.41.51.10.8
Pavlov. Cond. change in total contacts1.92.03.51.5-1.60.81.90.61.6
Pavlov. Cond. index score1.51.93.01.5-1.61.01.70.81.3
Pavlov. Cond. latency score1.82.33.71.6-1.71.01.90.91.7
Pavlov. Cond. lever contacts1.82.15.41.2-1.30.22.00.22.3
Pavlov. Cond. magazine entry number0.81.11.5-1.21.2-1.2-1.0-0.9-0.3
Pavlov. Cond. intertrial magazine entries3.03.65.02.2-2.22.11.72.10.6
Pavlov. Cond. lever-magazine prob. diff.1.31.62.61.3-1.50.91.60.71.3
Pavlov. Cond. response bias0.81.01.61.1-1.20.81.30.50.9
Pavlov. Cond. lever latency0.30.50.9-0.70.6-0.90.0-0.70.8
Pavlov. Cond. magazine entry latency0.00.00.2-0.00.00.1-0.20.5-0.0
Pavlov. Cond. change in total contacts0.10.20.40.4-0.30.60.00.5-0.4
Pavlov. Cond. index score0.50.61.00.9-0.81.00.41.0-0.2
Pavlov. Cond. latency score0.50.61.00.8-0.71.00.21.0-0.3
Pavlov. Cond. lever contacts0.10.10.30.4-0.40.50.20.2-0.3
Pavlov. Cond. magazine entry number0.00.00.20.1-0.10.20.0-0.3-0.4
Pavlov. Cond. intertrial magazine entries0.20.20.40.5-0.60.60.6-0.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.40.50.90.8-0.70.90.21.0-0.3
Pavlov. Cond. response bias0.10.20.40.4-0.40.60.10.4-0.4
Time in closed arm before self-admin0.80.92.5-0.20.2-1.20.4-1.61.0
Time in closed arm after self-admin0.10.10.20.2-0.3-0.10.4-0.30.4
Time in open arm before self-admin2.32.53.81.5-1.51.41.61.91.5
Time in open arm after self-admin0.30.31.20.4-0.40.60.21.10.1
Bone: periosteal estimation6.713.922.74.5-4.34.82.54.0-0.3
Bone: periosteal perimeter6.010.014.73.7-3.63.82.23.60.3
Bone: post-yield work3.04.16.12.5-2.42.21.62.20.7
Progressive ratio test 1 active lever presses1.11.22.81.0-0.90.31.7-0.31.5
Progressive ratio test 1 breakpoint1.31.43.21.1-1.10.41.8-0.31.5
Progressive ratio test 1 inactive lever presses1.92.14.71.5-1.50.92.20.41.5
Progressive ratio test 2 active lever presses0.40.40.90.7-0.71.00.50.6-0.1
Progressive ratio test 2 breakpoint0.30.30.70.6-0.60.80.50.3-0.3
Progressive ratio test 2 inactive lever presses1.01.22.31.2-1.21.50.61.2-0.3
Incentive Sensitization - Responses0.50.51.9-0.40.40.4-0.90.3-1.4
Incentive Sensitization - Breakpoint0.70.72.4-0.50.40.4-1.00.3-1.5
Sum of active levers in priming session hrs 5-60.10.10.30.2-0.2-0.10.6-0.10.4
Progressive ratio0.30.31.10.4-0.20.6-0.41.0-0.4
Food seeking constrained by brief footshock0.10.10.40.3-0.40.60.40.1-0.1
Seeking ratio, punishment vs. effort0.20.31.0-0.20.0-0.30.6-1.00.4
Retroperitoneal fat weight3.611.924.53.2-3.41.34.91.24.7
Reaction time number correct0.81.22.1-1.30.9-0.6-1.4-0.5-1.4
Reaction time mean minus median0.10.10.30.20.10.40.10.50.0
Reaction time mean minus median AUC0.40.51.3-0.40.80.3-0.90.3-1.2
Reaction time num false alarms2.02.74.52.0-2.11.31.71.11.4
Reaction time num false alarms AUC2.02.74.52.1-2.11.51.61.21.1
Reaction time trials correct on left0.81.22.1-1.30.9-0.6-1.4-0.5-1.4
Reaction time trials on left0.81.12.1-1.20.8-0.5-1.4-0.4-1.5
Reaction time mean0.60.92.2-0.51.10.2-1.20.2-1.5
Reaction time mean AUC0.60.81.7-0.61.20.0-1.1-0.1-1.3
Median of all reaction times0.81.02.7-0.61.20.1-1.30.0-1.6
Reaction time omissions0.20.30.60.5-0.30.80.30.6-0.3
Reaction time false alarm rate2.63.75.72.4-2.21.52.11.21.8
Reaction time premature initiation rate1.92.54.11.6-1.41.32.01.41.6
Reaction time premature initiations0.30.50.80.5-0.60.80.80.90.4
Std. dev. reaction times0.20.40.90.10.50.6-0.50.6-0.9
Reaction time trials completed0.81.12.1-1.20.8-0.5-1.4-0.4-1.5
Reaction time trials AUC0.91.22.3-1.30.9-0.6-1.5-0.5-1.5
Run reversals in cocaine runway, females3.73.613.90.7-1.0-0.82.3-0.33.7
Run reversals in cocaine runway, males0.30.20.5-0.60.5-0.2-0.7-0.1-0.5
Latency to leave start box in cocaine runway2.52.85.4-1.61.6-2.3-0.5-2.30.8
Latency to leave start box in cocaine runway, F1.61.83.5-1.01.1-1.90.2-1.71.5
Latency to leave start box in cocaine runway, M1.41.32.7-1.21.2-1.4-0.7-1.6-0.1
Std. dev. time between licks in bursts0.60.71.4-0.60.5-1.10.4-1.11.2
Total sessions with >9 infusions0.00.00.10.2-0.30.20.20.10.2
Short access day 1 total inactive lever presses0.10.10.10.3-0.30.30.30.30.0
Short access day 10 total inactive lever presses1.92.13.21.6-1.81.51.21.60.6
Short access day 1 total infusions0.10.10.3-0.30.3-0.40.0-0.50.2
Short access day 10 total infusions2.32.65.31.6-1.81.12.30.61.7
Short access total infusions0.40.50.90.8-0.80.71.00.20.4
Short access day 1 locomotion0.50.51.50.3-0.40.01.2-0.41.1
Short access day 10 total locomotion6.37.19.22.9-3.02.63.02.31.9
Short access total locomotion3.53.67.11.8-2.11.42.71.02.0
One hour access (0.3 mA shock)1.51.73.41.4-1.41.80.61.5-0.5
Compulsive drug intake1.41.43.11.0-1.01.6-0.11.7-0.9
One hour access (shock baseline)0.30.30.60.6-0.70.50.80.30.5
Social response proportion0.20.20.50.4-0.50.70.40.5-0.2
Social responses1.62.03.81.5-1.61.02.00.61.4
Social time0.40.51.00.8-0.90.80.31.00.0
Soleus weight0.72.03.21.5-1.80.81.51.21.5
Bone: stiffness0.91.42.21.5-1.31.51.01.20.3
Tibialis anterior weight1.03.510.01.3-1.50.12.70.23.2
Time to tail flick, vehicle, before self-admin0.90.92.30.6-0.51.2-0.31.5-0.8
Time to tail flick, vehicle, after self-admin0.60.71.30.4-0.31.1-0.51.1-1.0
Time to tail flick, test, before self-admin1.71.62.91.3-1.41.70.31.7-0.4
Time to tail flick, test, after self-admin0.91.02.31.0-0.71.50.21.2-0.7
Delta time to tail flick, vehicle, before/after SA0.40.41.6-0.20.30.3-0.7-0.2-1.2
Delta time to tail flick, test, before/after SA0.50.40.90.30.00.8-0.50.8-1.0
Tibia length1.13.13.92.0-2.01.61.81.81.4
Ambulatory time before self-admin0.50.50.9-0.90.7-0.6-0.9-0.4-0.8
Ambulatory time after self-admin0.80.91.5-1.11.1-1.1-0.5-1.2-0.3
Bone: tissue strength2.02.02.9-1.71.7-1.4-1.4-1.3-0.6
Total heroin consumption0.00.10.1-0.00.30.30.10.0-0.4
Bone: trabecular number0.81.33.7-0.90.8-0.2-1.5-0.5-1.9
Bone: trabecular spacing0.30.31.30.3-0.3-0.20.8-0.11.1
Bone: trabecular thickness0.91.11.81.1-1.21.40.51.2-0.4
Bone: trabecular tissue density0.00.00.1-0.10.1-0.00.10.20.3
Water consumed over 24 hours1.11.32.7-0.70.9-1.30.7-1.61.3
Number of responses in last shaping day0.60.71.40.7-0.80.21.20.21.2