Afap1l2

actin filament associated protein 1-like 2

chr1:265969368–266065951 (-)

Afap1l2 RatGTEx page

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Afap1l2 0.03 0.02 4.9e-04 0.03 0.02 0.03 0.02 6.3e-04 1.0e-03 4.5e-04 1.3e-03
2 NAcc mRNA stability Afap1l2 0.16 0.07 0.0e+00 0.15 0.16 0.15 0.16 9.5e-22 8.6e-23 1.3e-22 1.9e-23
3 IC mRNA stability Afap1l2 0.13 0.07 2.8e-05 0.1 0.11 0.11 0.1 5.9e-05 2.9e-05 3.3e-05 3.9e-05
4 LHb mRNA stability Afap1l2 0.5 0.19 2.0e-07 0.32 0.26 0.18 0.28 2.4e-08 8.2e-07 5.2e-05 2.9e-07
5 Brain mRNA stability Afap1l2 0.57 0.13 0.0e+00 0.45 0.44 0.44 0.45 8.2e-46 6.1e-45 1.6e-45 3.8e-46
6 Brain gene expression Afap1l2 0.2 0.09 0.0e+00 0.1 0.2 0.21 0.21 1.5e-09 1.4e-18 1.9e-19 2.4e-19
7 pVTA mRNA stability Afap1l2 0.25 0.11 0.0e+00 0.28 0.28 0.28 0.29 3.3e-22 4.5e-23 1.0e-22 2.8e-23
8 PL mRNA stability Afap1l2 0.2 0.09 0.0e+00 0.18 0.17 0.19 0.19 9.8e-20 3.3e-18 3.5e-20 4.3e-20
9 OFC mRNA stability Afap1l2 0.65 0.14 1.8e-09 0.35 0.4 0.36 0.37 4.7e-09 2.0e-10 2.3e-09 7.8e-10
10 IC intron excision ratio chr1_265989926_265993160 0.07 0.05 5.2e-03 0.03 0.03 0.01 0.06 2.0e-02 3.0e-02 1.0e-01 2.3e-03
11 IL mRNA stability Afap1l2 0.27 0.16 3.8e-04 0.16 0.12 0.11 0.12 1.3e-04 7.8e-04 1.4e-03 6.4e-04
12 NAcc gene expression Afap1l2 0.09 0.05 8.4e-11 0.02 0.07 0.06 0.06 8.8e-04 1.1e-10 2.4e-09 1.9e-09
13 IC isoform ratio XM_063282801.1 0.06 0.04 9.6e-03 0.03 0.03 0.01 -0.01 1.6e-02 3.1e-02 7.7e-02 6.5e-01
14 Adipose gene expression Afap1l2 0.04 0.03 8.5e-05 0.03 0.02 0.03 0.02 2.7e-04 9.5e-04 4.4e-04 8.8e-04
15 Liver mRNA stability Afap1l2 0.02 0.02 9.1e-03 0.01 0.01 0 0.01 1.0e-02 4.9e-02 7.5e-02 3.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density1.83.15.91.9-1.9-1.9-1.9-1.9-2.4-1.7-1.9-2.4-1.4-1.6-2.30.3-0.3-0.3
Area under the delay curve0.50.62.30.6-0.8-1.0-0.6-0.5-1.1-0.6-0.4-0.6-0.4-0.5-1.5-0.80.60.1
BMI with tail8.830.239.06.2-6.1-6.1-6.0-5.8-5.8-6.0-5.8-5.1-5.8-5.6-5.1-4.24.2-4.0
BMI without tail5.717.323.34.8-4.6-4.6-4.6-4.5-4.0-4.6-4.1-3.7-4.4-4.1-3.6-3.63.6-3.4
Body weight8.436.645.86.7-6.7-6.8-6.5-6.6-6.7-6.5-6.5-6.3-6.2-6.1-6.0-4.14.1-3.8
Weight adjusted by age7.010.514.73.5-3.5-3.4-3.6-3.6-2.6-3.7-3.8-2.5-3.8-3.8-2.1-2.72.7-2.7
Bone surface0.81.52.81.5-1.4-1.3-1.6-1.3-1.7-1.2-1.1-1.4-0.9-1.0-1.50.0-0.0-0.6
Bone volume2.44.46.62.4-2.4-2.3-2.5-2.3-2.6-2.2-2.2-2.4-1.9-2.0-2.4-0.70.7-1.1
Breakpoint value in progressive ratio session0.20.21.10.3-0.5-0.6-0.3-0.3-0.8-0.3-0.3-0.50.0-0.2-1.10.1-0.10.3
Number of licking bursts0.20.31.30.0-0.2-0.4-0.1-0.1-0.9-0.1-0.4-0.80.1-0.1-1.10.5-0.50.8
Context. condit. distance diff. score2.12.63.4-1.81.81.61.81.81.61.91.81.61.81.81.20.8-0.81.1
Locomotion velocity, session 10.10.10.4-0.10.20.30.00.20.60.10.20.40.00.10.6-0.30.3-0.2
Locomotion distance, session 10.20.30.90.4-0.1-0.1-0.2-0.30.8-0.3-0.10.5-0.6-0.20.8-0.60.6-1.0
Locomotion velocity, session 20.50.62.9-0.00.50.60.20.11.30.30.51.0-0.20.21.7-0.80.8-1.2
Locomotion distance, session 21.11.54.01.5-1.0-0.8-1.4-1.1-0.1-1.2-0.9-0.1-1.6-1.10.3-1.61.6-2.0
Locomotion velocity, session 30.20.31.40.00.40.20.10.11.20.20.10.5-0.4-0.11.0-0.20.2-0.9
Locomotion distance, session 30.50.51.8-0.10.70.50.20.41.30.40.61.0-0.10.31.3-0.60.6-0.9
Stereotopy head waving bouts, day 30.20.30.60.8-0.5-0.3-0.8-0.5-0.3-0.5-0.4-0.7-0.4-0.4-0.20.6-0.6-0.4
Stereotopy head waving duration, day 30.20.31.20.3-0.2-0.2-0.4-0.3-0.4-0.2-0.3-0.7-0.1-0.2-0.41.1-1.10.3
Locomotion velocity, session 70.30.40.50.7-0.5-0.7-0.7-0.6-0.6-0.7-0.5-0.4-0.6-0.7-0.5-0.60.6-0.7
Locomotion distance, session 70.10.10.3-0.00.20.2-0.00.3-0.00.10.20.50.10.10.3-0.40.5-0.5
Stereotopy head waving bouts, day 70.10.10.30.4-0.2-0.1-0.3-0.20.1-0.30.1-0.0-0.1-0.10.1-0.50.4-0.4
Stereotopy head waving duration, day 70.81.01.61.2-1.3-1.1-1.2-1.2-0.8-1.2-0.9-1.0-0.9-0.9-0.9-0.70.6-0.6
Locomotion velocity, session 82.73.24.5-1.81.92.01.72.01.92.02.11.82.02.11.51.3-1.21.1
Locomotion distance, session 81.72.53.9-1.51.81.81.71.62.01.81.81.91.31.62.00.6-0.60.4
Degree of sensitization distance0.40.41.2-0.60.20.40.50.7-0.70.40.4-0.00.90.6-0.70.8-0.71.1
Degree of sensitization stereotypy0.00.00.10.3-0.3-0.2-0.2-0.2-0.1-0.3-0.0-0.2-0.1-0.1-0.2-0.40.3-0.1
Conditioned locomotion0.10.10.4-0.30.30.40.20.30.40.20.20.50.10.10.60.00.0-0.2
Cocaine response after cond. corrected1.82.25.5-1.11.51.71.11.32.21.31.92.31.11.42.4-0.40.3-0.5
Cocaine response after cond. not corrected2.32.75.6-1.41.81.91.41.62.21.52.12.21.41.72.40.1-0.1-0.1
Cocaine response before conditioning0.40.51.9-0.50.40.30.50.4-0.50.40.1-0.50.60.4-0.41.4-1.31.2
Saline control response0.20.21.4-0.00.20.40.10.00.60.00.40.5-0.00.21.2-0.20.3-0.7
Bone: connectivity density0.20.41.00.6-0.5-0.4-0.6-0.4-1.0-0.3-0.4-0.7-0.1-0.2-0.91.0-1.00.2
Bone: cortical apparent density1.11.55.5-0.61.21.10.80.81.90.91.12.00.20.72.4-0.70.8-1.0
Bone: cortical area9.314.319.84.5-4.2-4.1-4.4-4.2-4.1-4.2-4.0-4.1-3.9-3.9-3.3-1.81.8-2.8
Bone: cortical porosity0.20.21.3-0.40.20.40.30.2-0.10.30.2-0.10.40.20.11.1-1.10.5
Bone: cortical porosity0.40.41.9-0.0-0.2-0.0-0.1-0.2-0.70.0-0.3-0.70.2-0.1-0.61.4-1.40.6
Bone: cortical thickness4.57.510.93.3-2.9-2.9-3.3-3.1-2.7-3.0-2.9-2.7-3.1-3.0-1.8-1.41.4-2.5
Bone: cortical thickness1.92.23.31.8-1.5-1.5-1.8-1.6-1.3-1.7-1.5-1.1-1.8-1.7-0.6-1.21.2-1.8
Bone: cortical tissue density1.31.86.0-0.91.41.31.01.12.11.11.32.10.40.92.4-0.60.6-0.8
Condit. Reinf. active minus inactive responses0.10.20.4-0.30.50.50.40.10.30.5-0.10.2-0.2-0.10.60.6-0.60.1
Condit. Reinf. active-inactive response ratio0.20.20.5-0.50.50.40.70.20.20.5-0.10.00.00.00.40.7-0.70.5
Condit. Reinf. active responses0.70.91.91.1-0.8-0.8-1.0-1.4-0.7-0.8-1.4-1.2-1.4-1.3-0.3-0.10.1-0.8
Condit. Reinf. inactive responses2.12.64.32.0-1.7-1.5-2.1-2.0-1.4-1.7-1.8-1.9-1.8-1.7-1.0-0.60.7-1.4
Incentive salience index mean0.20.21.1-0.30.60.60.40.10.50.5-0.00.4-0.2-0.11.10.4-0.4-0.2
Condit. Reinf. lever presses0.10.10.60.00.30.30.0-0.20.20.2-0.20.3-0.4-0.30.8-0.10.0-0.5
Condit. Reinf. active minus inactive responses2.53.37.11.7-1.8-2.0-1.7-1.9-2.3-1.8-2.2-2.7-1.6-1.9-2.40.2-0.2-0.2
Condit. Reinf. active-inactive response ratio0.80.92.10.7-1.0-1.0-0.7-1.0-1.2-0.8-1.3-1.5-0.8-1.1-1.40.2-0.30.2
Condit. Reinf. active responses3.95.510.02.4-2.4-2.7-2.3-2.5-3.0-2.4-2.7-3.2-2.2-2.3-3.0-0.20.2-0.6
Condit. Reinf. inactive responses1.41.83.41.5-1.4-1.6-1.5-1.4-1.8-1.4-1.4-1.8-1.3-1.1-1.8-0.20.3-0.5
Condit. Reinf. lever presses0.71.02.30.9-1.1-1.2-0.9-0.9-1.3-1.0-1.1-1.3-0.9-0.8-1.5-0.30.3-0.0
Condit. Reinf. lever reinforcers received2.83.97.41.9-2.0-2.3-1.9-2.1-2.5-2.0-2.4-2.7-1.9-2.0-2.5-0.10.1-0.4
Conditioned reinforcement - actives0.30.51.90.5-0.1-0.0-0.4-0.30.7-0.20.20.5-0.5-0.11.0-1.11.1-1.4
Conditioned reinforcement - inactives0.40.60.90.9-0.9-0.9-0.7-0.9-0.8-0.8-0.7-0.6-0.9-0.8-0.5-0.80.9-0.5
Conditioned locomotion0.40.51.60.4-0.00.1-0.3-0.31.1-0.20.20.7-0.6-0.21.2-1.11.1-1.3
Patch foraging indifference point 0 sec3.97.28.82.8-3.0-2.8-2.8-2.9-2.7-3.0-2.8-2.5-2.7-2.7-2.3-2.62.6-1.8
Patch foraging indifference point AUC0.30.41.00.6-0.9-0.8-0.8-0.7-0.8-0.8-0.5-0.9-0.2-0.4-1.0-0.10.2-0.0
Delay disc. indifference point, 0s delay0.20.20.70.6-0.4-0.5-0.5-0.3-0.5-0.4-0.0-0.0-0.4-0.2-0.4-0.80.8-0.3
Delay disc. indifference point, 16s delay0.20.21.30.1-0.4-0.5-0.2-0.1-0.8-0.2-0.1-0.30.1-0.1-1.2-0.40.30.4
Delay disc. indifference point, 2s delay0.50.61.2-0.80.80.50.90.90.50.81.11.10.80.90.2-0.30.30.6
Delay disc. indifference point, 24s delay0.40.52.60.1-0.6-0.7-0.2-0.3-1.4-0.3-0.4-1.00.0-0.3-1.6-0.0-0.10.8
Delay disc. indifference point, 4s delay0.20.20.5-0.50.50.20.60.7-0.10.50.60.60.50.6-0.3-0.00.10.6
Delay disc. indifference point, 8s delay4.75.57.82.5-2.7-2.8-2.5-2.5-2.3-2.6-2.3-2.1-2.4-2.4-2.5-2.12.0-1.4
Indifference point function ln k0.00.10.3-0.10.30.30.30.10.10.3-0.20.1-0.3-0.20.50.2-0.40.1
Indifference point function log k0.00.10.3-0.10.30.30.30.10.10.3-0.20.1-0.3-0.20.50.2-0.40.1
Patch foraging total patch changes 0 sec3.87.18.92.8-3.0-2.9-2.8-2.8-2.7-3.0-2.7-2.5-2.6-2.6-2.4-2.52.6-1.7
Patch foraging total patch changes 12 sec1.41.93.21.5-1.6-1.6-1.6-1.3-1.7-1.6-1.1-1.4-0.9-0.9-1.8-1.11.2-0.7
Patch foraging total patch changes 18 sec3.65.67.82.5-2.8-2.7-2.6-2.5-2.7-2.7-2.4-2.8-2.0-2.2-2.8-1.31.4-1.1
Patch foraging total patch changes 24 sec2.13.66.02.0-2.4-2.3-2.1-1.9-2.2-2.2-1.7-2.0-1.4-1.5-2.5-1.31.4-0.8
Patch foraging total patch changes 6 sec5.58.410.93.2-3.3-3.3-3.2-3.2-3.0-3.3-3.0-3.0-2.8-2.8-2.9-2.12.2-1.9
Patch foraging time to switch 0 sec0.61.22.0-1.21.31.11.31.41.21.21.31.41.11.30.90.2-0.30.5
Patch foraging water rate 0 sec0.81.72.41.5-1.4-1.3-1.5-1.5-1.4-1.5-1.4-1.4-1.3-1.4-1.1-0.70.7-0.8
Patch foraging water rate 12 sec1.53.15.11.9-2.0-1.9-2.0-1.9-2.3-1.9-1.9-2.2-1.5-1.8-2.1-0.30.4-0.7
Patch foraging water rate 18 sec0.71.01.61.2-1.1-0.9-1.1-1.1-0.4-1.2-1.0-0.6-1.3-1.2-0.1-1.00.9-1.3
Patch foraging water rate 24 sec1.01.42.21.4-1.2-1.1-1.3-1.2-0.8-1.4-1.2-0.7-1.4-1.3-0.5-1.21.3-1.5
Patch foraging water rate 6 sec0.71.02.21.4-1.1-0.9-1.4-0.9-0.5-1.3-0.8-0.5-1.0-0.9-0.4-0.91.0-1.5
Seeking ratio, delayed vs. immediate footshock0.91.12.8-1.11.31.41.11.01.41.21.11.20.60.71.70.3-0.40.2
Distance traveled before self-admin1.21.64.1-0.81.41.21.01.11.81.11.52.00.61.22.0-0.40.3-0.6
Distance traveled after self-admin0.81.03.4-0.40.90.90.50.71.50.60.91.60.20.61.8-0.80.8-1.0
Extensor digitorum longus weight0.41.53.51.2-1.2-1.3-1.3-1.0-1.9-1.2-1.4-1.5-1.0-1.1-1.80.2-0.1-0.3
Bone: elastic displacement0.20.20.8-0.90.30.20.70.50.30.40.40.10.50.40.00.2-0.20.7
Bone: elastic work0.50.61.90.8-0.6-0.7-0.9-0.80.1-0.8-0.6-0.3-1.0-0.90.2-1.01.0-1.4
Bone: endosteal estimation1.32.93.81.9-1.9-1.9-1.9-1.8-1.8-1.9-1.8-1.9-1.5-1.7-1.9-1.21.1-1.0
Bone: endosteal perimeter5.110.813.73.7-3.7-3.7-3.6-3.6-3.1-3.6-3.4-3.1-3.4-3.3-2.9-2.72.7-2.6
Epididymis fat weight10.837.057.26.6-6.7-6.7-6.5-6.6-7.6-6.4-6.6-6.9-5.9-6.0-6.7-3.43.4-3.1
Delta time in closed arm before/after self-admin0.30.31.0-0.10.50.50.10.30.50.40.60.60.10.41.0-0.60.6-0.6
Delta time in open arm before/after self-admin1.21.22.30.8-1.2-1.2-0.9-1.0-1.3-1.2-1.5-1.4-0.8-1.2-1.50.2-0.20.2
Diff in mean of infusions in LGA sessions1.11.32.5-1.31.00.91.31.30.81.31.10.81.51.10.01.2-1.01.6
Delay discount exponential model param0.50.52.2-0.50.81.00.50.51.10.60.40.60.40.51.50.8-0.6-0.1
Extinction: sum of active levers before priming0.50.51.6-0.80.60.40.80.90.00.80.70.41.00.9-0.40.6-0.61.3
Active lever presses in extinction session 60.10.10.30.0-0.0-0.30.0-0.10.10.10.2-0.20.10.1-0.40.5-0.50.2
Bone: final force3.65.78.82.9-2.6-2.4-3.0-2.7-2.1-2.7-2.3-2.1-2.5-2.5-1.4-1.81.8-2.6
Bone: final moment3.45.48.12.8-2.5-2.4-2.8-2.6-2.1-2.6-2.3-2.1-2.4-2.4-1.5-1.71.7-2.4
Food consumed during 24 hour testing period0.60.81.4-0.91.10.90.91.00.51.20.80.50.81.00.71.1-1.20.8
Glucose1.92.94.12.0-2.0-1.9-2.0-2.0-1.6-1.9-1.8-1.9-1.8-1.9-1.3-0.90.9-1.3
Heart weight2.64.05.52.3-2.3-2.2-2.3-2.3-2.4-2.2-2.3-2.1-2.0-2.2-2.0-0.80.8-1.0
Delay discount hyperbolic model param0.30.31.6-0.40.60.80.30.30.90.40.30.30.30.31.20.7-0.6-0.1
Intermittent access intake day 1-15 change0.81.63.41.4-1.2-1.5-1.2-1.3-0.7-1.3-1.0-0.5-1.7-1.2-0.5-1.91.8-1.1
Intermittent access intake escalation0.61.32.31.2-1.1-1.4-1.0-1.2-0.8-1.1-1.0-0.7-1.5-1.1-0.7-1.41.4-0.7
Intermittent access intake escalation 20.80.92.11.0-0.8-0.9-0.8-0.9-0.2-0.9-0.7-0.1-1.3-0.9-0.0-1.51.4-1.1
Intermitt. access day 1 inactive lever presses0.62.25.21.4-1.7-1.7-1.4-1.5-2.3-1.5-1.7-1.9-1.2-1.4-2.2-0.20.20.2
Intermitt. access day 15 inactive lever presses0.10.20.70.2-0.5-0.6-0.2-0.5-0.9-0.5-0.6-0.4-0.5-0.6-0.6-0.10.20.2
Intermitt. access escalation Index0.20.30.5-0.50.60.50.50.60.60.60.70.40.50.70.40.4-0.60.3
Intermittent access day 1 total infusions0.30.51.30.8-0.6-0.5-0.8-0.6-0.2-0.7-0.4-0.1-0.6-0.6-0.0-0.91.0-1.1
Intermittent access day 15 total infusions0.40.51.70.8-0.6-0.8-0.7-0.7-0.2-0.7-0.2-0.0-0.8-0.5-0.2-1.31.3-0.8
Intermittent access terminal intake (last 3 days)0.20.20.90.5-0.4-0.5-0.4-0.30.0-0.40.00.2-0.4-0.1-0.0-0.90.9-0.7
Intermittent access total infusions1.21.52.61.5-1.2-1.2-1.3-1.3-0.6-1.3-0.9-0.5-1.4-1.2-0.3-1.51.4-1.6
Intermittent access day 1 locomotion0.40.52.00.6-0.4-0.4-0.6-0.50.2-0.60.10.5-0.4-0.30.3-1.41.4-1.3
Intermittent access day 15 total locomotion1.73.15.42.0-2.1-2.3-1.8-2.0-1.7-2.1-1.6-1.6-1.8-1.7-1.9-1.31.3-1.0
Intermittent access total locomotion1.31.53.61.4-1.1-1.2-1.2-1.3-0.2-1.3-0.7-0.1-1.3-1.10.1-1.91.8-1.8
Intermittent access standard deviation0.61.22.61.1-1.1-1.3-1.0-1.0-1.2-1.1-0.9-0.6-1.0-0.9-1.1-1.51.6-0.5
Left kidney weight1.04.58.52.4-2.1-2.0-2.2-2.0-1.3-2.2-1.8-1.1-2.2-2.2-0.9-2.92.9-2.4
Right kidney weight2.511.217.23.7-3.3-3.3-3.5-3.5-2.1-3.6-3.0-2.0-3.9-3.5-1.3-4.14.0-3.9
Cocaine induced anxiety5.17.39.4-3.02.93.03.03.02.82.93.12.92.82.82.61.4-1.41.7
Post-drug Anxiety1.41.52.5-1.41.21.11.31.40.71.31.10.71.41.30.41.6-1.41.4
Baseline Anxiety3.54.06.92.0-2.1-2.3-2.1-2.1-2.5-2.0-2.4-2.6-1.9-2.0-2.60.1-0.0-0.6
Tail length0.10.30.60.5-0.6-0.7-0.4-0.6-0.6-0.5-0.6-0.8-0.4-0.4-0.7-0.20.2-0.0
Length with tail0.94.06.22.0-2.2-2.2-1.9-2.3-2.4-2.0-2.3-2.5-2.0-2.1-2.1-1.00.9-0.8
Length without tail3.110.016.43.2-3.3-3.5-3.2-3.4-4.0-3.1-3.8-4.0-3.2-3.4-3.4-1.11.1-1.3
LgA early post infusion interval0.40.51.4-0.90.60.70.90.80.60.70.81.20.90.70.7-0.60.40.3
LgA late post infusion interval0.20.30.7-0.70.40.40.60.4-0.00.50.50.10.80.5-0.20.7-0.60.8
LgA early loading0.61.14.00.1-0.4-0.7-0.2-0.3-1.3-0.2-0.7-1.70.1-0.1-2.01.7-1.51.5
LgA late loading0.00.10.20.10.1-0.4-0.00.10.3-0.10.00.1-0.50.2-0.0-0.40.4-0.3
LgA early average infusions1.01.35.6-0.1-0.1-0.30.0-0.2-0.90.1-0.3-1.60.30.2-1.62.4-2.11.6
LgA late average infusions0.91.31.91.2-1.1-1.4-1.1-1.0-1.3-1.2-1.4-1.2-1.3-1.0-1.3-0.60.7-0.6
LgA early timeout0.80.91.90.9-0.8-0.9-1.0-1.0-1.2-0.8-1.1-1.4-0.9-0.8-1.20.6-0.50.0
LgA late timeout0.60.72.00.9-0.5-0.6-0.8-1.0-0.4-0.7-1.1-0.4-1.4-1.10.2-0.70.9-1.1
LgA early titration0.60.92.90.1-0.2-0.5-0.2-0.1-1.0-0.1-0.5-1.40.10.0-1.61.7-1.51.3
LgA late titration1.42.13.81.5-1.6-1.7-1.5-1.4-1.8-1.5-1.6-1.8-1.4-1.2-1.9-0.60.6-0.5
LgA total infusion0.91.22.91.1-1.1-1.3-1.1-1.1-1.4-1.0-1.2-1.7-0.9-0.8-1.70.3-0.20.0
Times rat made contact with spout0.10.10.20.2-0.1-0.2-0.1-0.20.0-0.1-0.10.1-0.4-0.20.2-0.40.4-0.5
Lifetime Intake1.41.73.01.6-1.3-1.2-1.4-1.4-0.6-1.4-1.0-0.5-1.5-1.3-0.2-1.51.5-1.7
Liver weight, left3.35.47.52.7-2.6-2.7-2.6-2.4-2.7-2.6-2.1-2.2-2.1-2.0-2.5-1.81.9-1.6
Liver weight, right4.17.110.13.1-2.7-2.6-2.9-2.8-1.8-2.8-2.4-1.5-3.0-2.8-1.2-3.23.2-3.0
Locomotor activity1.11.72.61.5-1.3-1.3-1.4-1.5-0.8-1.4-1.2-0.9-1.6-1.3-0.4-1.41.4-1.6
Locomotor testing distance1.22.25.71.8-1.2-1.2-1.6-1.5-0.3-1.5-1.0-0.4-1.8-1.40.2-2.02.0-2.4
Locomotor testing rearing0.40.82.50.9-0.5-0.7-0.8-0.7-0.1-0.8-0.5-0.2-1.1-0.70.2-1.51.5-1.6
Locomotion in novel chamber0.81.03.6-0.71.01.10.70.71.40.81.21.50.41.01.9-0.30.3-0.7
Locomotion in novel chamber post-restriction0.71.14.3-0.71.21.30.70.81.70.91.01.40.60.72.1-0.10.1-0.6
Fecal boli incidents, locomotor time 11.52.23.11.7-1.6-1.4-1.6-1.8-1.5-1.6-1.6-1.6-1.7-1.8-0.8-1.01.0-1.1
Change in fecal boli incidents, locomotor task4.44.46.7-2.62.32.22.62.31.92.52.01.82.22.31.41.6-1.61.8
Time >=10cm from walls, locomotor time 12.62.84.8-1.81.81.81.51.81.71.81.41.11.71.61.22.1-2.21.2
Bouts of movement, locomotor time 11.31.52.61.3-1.5-1.4-1.2-1.2-1.4-1.3-1.0-1.3-1.0-1.1-1.6-0.90.9-0.4
Total resting periods, locomotor time 11.01.11.61.2-1.3-1.2-1.1-1.1-1.1-1.2-0.9-1.0-0.9-1.0-1.2-0.90.9-0.5
Rest time, locomotor task time 10.81.12.71.1-1.0-0.7-1.1-0.9-0.4-1.1-0.5-0.2-1.0-0.80.1-1.61.5-1.6
Distance moved, locomotor task time 10.40.62.1-0.90.80.40.80.70.40.70.40.10.60.5-0.31.4-1.31.3
Vertical activity count, locomotor time 10.82.03.1-1.51.51.31.41.51.51.51.31.01.41.30.71.8-1.61.4
Time >=10cm from walls, locomotor time 20.10.21.1-0.20.20.20.00.20.00.30.1-0.50.50.3-0.41.0-1.00.7
Bouts of movement, locomotor time 21.42.33.9-1.61.51.51.51.91.41.52.01.71.91.80.90.8-0.81.1
Total resting periods, locomotor time 20.81.32.7-1.21.11.11.21.61.11.11.61.41.51.50.50.5-0.40.7
Rest time, locomotor task time 20.30.41.70.6-0.5-0.5-0.5-0.3-0.2-0.6-0.00.0-0.5-0.2-0.2-1.31.2-0.8
Distance moved, locomotor task time 20.30.30.60.6-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.7-0.4-0.4-0.80.7-0.60.3
Vertical activity count, locomotor time 20.20.20.40.6-0.5-0.3-0.7-0.6-0.4-0.4-0.4-0.7-0.4-0.3-0.30.6-0.6-0.0
Light reinforcement 11.43.44.3-2.12.02.02.12.01.91.91.71.71.81.71.41.8-1.91.4
Light reinforcement 22.74.15.4-2.02.22.31.92.12.32.12.32.22.12.22.11.5-1.61.0
Bone: marrow area1.43.03.81.9-2.0-1.9-1.9-1.8-1.8-1.9-1.8-1.9-1.5-1.7-1.9-1.21.2-1.0
Bone: maximum diameter7.814.518.94.4-4.2-4.2-4.3-4.2-4.3-4.1-4.1-4.3-3.8-3.8-3.8-1.81.8-2.5
Bone: maximum force2.44.36.82.6-2.2-2.1-2.6-2.4-1.8-2.3-2.1-1.9-2.2-2.2-1.3-1.31.3-2.2
Bone: maximum moment2.23.95.82.4-2.1-2.0-2.4-2.3-1.8-2.2-2.0-1.9-2.1-2.1-1.3-1.11.1-1.9
Mean time between licks in bursts0.10.31.1-0.40.30.30.40.5-0.30.5-0.0-0.30.30.2-0.31.1-1.10.8
Mean num. licks in bursts0.40.62.20.4-0.00.0-0.2-0.30.8-0.30.00.7-0.7-0.31.3-1.01.1-1.5
Cd content in liver1.11.24.1-0.81.21.30.80.91.80.91.21.50.70.82.0-0.10.1-0.3
Co content in liver0.40.42.20.0-0.00.2-0.0-0.20.4-0.10.10.5-0.2-0.30.9-1.51.5-0.7
Cu content in liver0.10.10.4-0.20.30.30.20.20.30.20.50.60.30.30.5-0.40.4-0.2
Fe content in liver0.81.02.70.8-1.0-1.0-0.9-0.9-1.6-0.7-1.1-1.6-0.5-0.9-1.60.4-0.40.3
K content in liver0.30.30.5-0.50.40.50.50.60.50.40.60.70.50.50.5-0.50.50.0
Mg content in liver0.60.61.3-0.80.70.70.71.00.70.71.10.91.01.00.4-0.30.30.4
Mn content in liver0.91.01.8-1.01.01.01.01.30.91.01.31.21.21.20.60.0-0.00.6
Na content in liver0.40.40.8-0.90.50.50.90.80.50.60.80.70.90.70.10.0-0.00.8
Rb content in liver2.32.64.7-1.91.71.51.71.90.91.71.91.12.21.90.51.4-1.41.7
Se content in liver0.70.81.4-1.00.80.80.91.01.00.90.90.61.20.90.30.9-0.90.9
Sr content in liver2.21.94.1-1.21.51.61.21.41.91.21.62.01.11.31.9-0.10.10.3
Zn content in liver1.01.12.5-0.91.01.20.91.11.20.91.61.61.11.21.2-0.30.30.2
Bone: minimum diameter3.36.19.22.9-2.8-2.7-2.9-2.6-3.0-2.7-2.5-2.8-2.2-2.3-2.7-1.11.0-1.4
Time in familiar zone, hab. session 10.10.10.20.1-0.0-0.0-0.0-0.20.0-0.1-0.30.0-0.5-0.40.4-0.30.4-0.3
Time in novel zone, hab. session 10.30.31.40.5-0.7-0.7-0.5-0.4-0.8-0.5-0.4-0.8-0.1-0.2-1.20.2-0.20.3
Total zone transitions, hab. session 11.01.42.71.5-1.2-1.2-1.4-1.3-0.3-1.3-0.9-0.4-1.4-1.1-0.3-1.21.3-1.6
Total locomotion distance, hab. session 10.40.51.0-0.70.80.70.70.70.70.80.60.50.60.60.51.0-1.00.6
Locomotion velocity, hab. session 10.60.81.2-0.91.00.91.01.01.01.00.80.80.80.80.81.1-1.00.7
Time in familiar zone, hab. session 21.41.54.70.7-1.1-1.4-0.7-1.1-1.9-0.9-1.5-1.7-0.9-1.2-2.20.0-0.10.7
Time in novel zone, hab. session 20.50.52.70.10.30.7-0.00.21.20.20.61.0-0.10.21.6-0.40.4-1.3
Total zone transitions, hab. session 21.41.82.81.6-1.4-1.4-1.4-1.4-0.7-1.6-1.3-0.6-1.7-1.5-0.6-1.51.5-1.6
Total locomotion distance, hab. session 20.00.00.10.20.0-0.10.00.00.1-0.1-0.20.1-0.3-0.20.1-0.00.0-0.2
Locomotion velocity, hab. session 20.00.00.10.00.10.00.10.20.30.00.00.3-0.10.10.2-0.00.1-0.2
Novel to familiar place preference ratio0.20.20.90.1-0.10.1-0.2-0.2-0.3-0.0-0.1-0.60.20.1-0.30.9-0.90.4
Novelty place preference0.10.10.60.3-0.20.0-0.3-0.3-0.3-0.1-0.2-0.70.1-0.0-0.20.7-0.70.2
Time in novel zone, NPP test0.40.41.20.6-0.5-0.4-0.6-0.6-0.8-0.5-0.6-1.1-0.2-0.4-0.80.7-0.70.2
Total zone transitions, NPP test0.30.41.10.9-0.6-0.6-0.7-0.5-0.2-0.7-0.30.1-0.7-0.4-0.2-1.11.1-0.9
Total locomotion distance, NPP test0.10.10.2-0.20.40.30.30.40.40.40.30.40.30.40.20.3-0.20.3
Locomotion velocity, NPP test0.40.61.0-0.60.90.80.70.91.00.80.80.90.70.80.80.3-0.30.3
Intraocular pressure4.66.69.72.7-2.8-2.9-2.7-3.0-2.8-2.7-3.1-2.8-2.8-2.9-2.5-1.11.1-1.5
Delta distance traveled before/after self-admin0.10.10.70.1-0.2-0.2-0.1-0.00.1-0.2-0.00.1-0.1-0.1-0.0-0.80.9-0.3
Delta ambulatory time before/after self-admin0.10.10.40.2-0.4-0.5-0.2-0.2-0.3-0.3-0.2-0.4-0.1-0.2-0.6-0.40.50.1
Parametrial fat weight12.830.040.75.9-6.1-6.2-5.7-6.0-6.4-5.9-6.2-6.0-5.4-5.8-6.0-3.03.0-2.5
Pavlov. Cond. lever latency0.10.10.6-0.1-0.2-0.30.0-0.0-0.4-0.1-0.1-0.50.10.1-0.70.1-0.10.7
Pavlov. Cond. magazine entry latency0.00.00.1-0.00.30.10.2-0.0-0.20.1-0.30.1-0.3-0.20.20.2-0.3-0.0
Pavlov. Cond. change in total contacts0.00.00.30.3-0.00.0-0.2-0.1-0.0-0.1-0.00.2-0.3-0.10.2-0.20.1-0.5
Pavlov. Cond. index score0.10.10.40.4-0.1-0.1-0.3-0.3-0.2-0.2-0.4-0.0-0.5-0.40.1-0.20.1-0.6
Pavlov. Cond. latency score0.10.10.50.4-0.1-0.1-0.3-0.3-0.1-0.3-0.30.0-0.5-0.40.2-0.30.2-0.7
Pavlov. Cond. lever contacts0.00.10.30.2-0.1-0.0-0.2-0.20.1-0.1-0.10.1-0.3-0.30.3-0.20.2-0.6
Pavlov. Cond. magazine entry number0.50.61.4-0.90.50.70.70.90.70.71.00.51.21.00.20.3-0.20.9
Pavlov. Cond. intertrial magazine entries0.20.20.60.6-0.4-0.3-0.5-0.8-0.1-0.3-0.6-0.6-0.6-0.60.10.0-0.0-0.4
Pavlov. Cond. lever-magazine prob. diff.0.00.10.20.3-0.0-0.1-0.2-0.3-0.3-0.1-0.3-0.1-0.4-0.30.10.0-0.1-0.4
Pavlov. Cond. response bias0.00.10.20.20.10.0-0.1-0.2-0.1-0.1-0.30.1-0.4-0.30.30.1-0.2-0.5
Pavlov. Cond. lever latency0.40.51.4-0.60.90.80.50.71.10.70.81.10.50.41.20.0-0.1-0.3
Pavlov. Cond. magazine entry latency0.30.41.50.4-0.7-0.9-0.3-0.6-0.8-0.5-0.7-0.8-0.5-0.4-1.2-0.0-0.00.2
Pavlov. Cond. change in total contacts0.71.12.50.9-1.2-1.3-0.8-1.2-1.4-1.0-1.3-1.6-1.0-0.9-1.40.0-0.00.0
Pavlov. Cond. index score0.81.12.10.9-1.2-1.3-0.8-1.2-1.3-1.1-1.3-1.4-1.0-1.0-1.4-0.20.2-0.0
Pavlov. Cond. latency score0.81.02.00.8-1.2-1.2-0.8-1.1-1.3-1.0-1.2-1.4-1.0-0.9-1.4-0.20.20.1
Pavlov. Cond. lever contacts0.30.40.70.6-0.8-0.8-0.6-0.7-0.8-0.7-0.7-0.8-0.6-0.5-0.8-0.40.4-0.0
Pavlov. Cond. magazine entry number0.30.31.3-0.40.60.80.30.50.80.50.70.80.50.41.10.2-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.00.00.20.2-0.0-0.3-0.2-0.0-0.5-0.2-0.0-0.10.0-0.1-0.4-0.00.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.91.11.81.0-1.2-1.3-0.9-1.2-1.3-1.1-1.3-1.3-1.1-1.0-1.3-0.40.4-0.2
Pavlov. Cond. response bias0.50.71.60.8-1.0-1.0-0.7-0.9-1.1-0.8-1.0-1.2-0.8-0.7-1.3-0.10.10.0
LgA PC1 addiction-like behavior0.10.20.50.3-0.2-0.5-0.3-0.2-0.3-0.3-0.4-0.7-0.5-0.0-0.70.4-0.20.2
Time in closed arm before self-admin0.30.30.6-0.80.50.50.70.70.50.50.80.70.70.70.30.3-0.30.4
Time in closed arm after self-admin1.61.73.3-1.31.31.41.21.51.41.31.81.71.41.51.6-0.30.30.2
Time in open arm before self-admin1.41.52.4-1.11.41.41.21.21.01.51.40.81.31.50.81.3-1.31.0
Time in open arm after self-admin0.60.71.70.7-0.8-0.7-0.8-0.9-0.9-0.9-1.3-1.1-0.7-1.1-0.80.5-0.4-0.2
Bone: periosteal estimation5.211.015.23.9-3.7-3.6-3.9-3.7-3.5-3.7-3.5-3.5-3.3-3.4-3.0-1.91.9-2.4
Bone: periosteal perimeter11.519.825.75.1-4.9-4.9-5.1-4.9-4.5-4.9-4.6-4.4-4.6-4.6-3.9-3.13.1-3.5
Bone: post-yield work0.30.41.6-0.30.50.50.30.5-0.20.60.40.10.70.6-0.11.2-1.30.9
Progressive ratio test 1 active lever presses0.81.02.41.2-0.9-1.0-1.1-1.1-0.2-1.1-0.6-0.2-1.1-0.9-0.1-1.41.4-1.6
Progressive ratio test 1 breakpoint0.91.12.71.3-0.9-1.0-1.2-1.1-0.2-1.2-0.6-0.1-1.1-0.9-0.0-1.41.4-1.7
Progressive ratio test 1 inactive lever presses0.10.10.20.4-0.3-0.5-0.3-0.5-0.2-0.3-0.3-0.2-0.4-0.4-0.2-0.40.3-0.3
Progressive ratio test 2 active lever presses1.51.82.71.6-1.5-1.7-1.4-1.5-0.8-1.5-1.1-0.8-1.5-1.3-0.9-1.41.3-1.3
Progressive ratio test 2 breakpoint1.61.92.91.6-1.6-1.7-1.4-1.6-0.9-1.6-1.2-0.9-1.5-1.3-1.0-1.41.3-1.3
Progressive ratio test 2 inactive lever presses1.32.13.11.6-1.6-1.6-1.5-1.8-1.7-1.5-1.5-1.4-1.5-1.6-1.2-0.90.9-0.8
ShA PR total presses1.31.56.5-1.00.70.40.90.6-0.50.90.1-0.70.80.7-0.92.5-2.42.1
Incentive Sensitization - Responses0.81.22.01.2-1.3-1.4-1.1-1.2-1.2-1.2-1.0-1.1-1.1-1.0-1.2-0.80.7-0.5
Incentive Sensitization - Breakpoint0.81.11.91.1-1.2-1.4-1.0-1.2-1.1-1.1-1.0-1.1-1.0-0.9-1.2-0.60.5-0.3
LgA PR total presses1.11.22.0-1.21.41.11.21.21.21.21.01.00.81.21.11.0-1.00.6
Sum of active levers in priming session hrs 5-60.30.20.5-0.60.40.40.50.40.50.40.30.30.60.30.10.7-0.70.6
Progressive ratio0.50.81.2-0.90.90.70.91.00.90.90.90.50.90.90.31.1-0.90.9
Food seeking constrained by brief footshock1.31.63.5-1.41.20.71.51.50.41.41.30.51.41.6-0.51.4-1.31.9
Seeking ratio, punishment vs. effort0.00.10.5-0.0-0.1-0.20.1-0.0-0.3-0.0-0.10.1-0.20.1-0.2-0.70.5-0.1
Retroperitoneal fat weight11.247.971.47.4-7.7-7.8-7.3-7.5-8.4-7.2-7.7-7.6-6.7-7.0-7.8-3.93.9-3.1
Reaction time number correct0.61.21.91.3-1.3-1.4-1.2-1.1-1.4-1.3-1.1-1.2-1.0-1.1-1.4-0.30.3-0.7
Reaction time mean minus median0.30.91.41.0-0.9-1.1-0.9-0.9-0.5-1.0-1.0-0.5-1.2-1.1-0.5-1.00.9-1.1
Reaction time mean minus median AUC0.30.82.50.8-0.6-0.8-0.7-0.60.1-0.8-0.60.1-1.1-0.80.1-1.61.5-1.4
Reaction time num false alarms0.10.10.40.3-0.00.1-0.3-0.10.2-0.00.10.2-0.10.10.2-0.70.6-0.5
Reaction time num false alarms AUC0.10.20.90.4-0.2-0.0-0.4-0.20.3-0.20.00.2-0.2-0.10.3-0.90.8-0.7
Reaction time trials correct on left0.61.21.91.3-1.3-1.4-1.2-1.1-1.4-1.3-1.1-1.2-1.0-1.1-1.4-0.30.3-0.7
Reaction time trials on left0.71.42.11.3-1.4-1.4-1.2-1.2-1.4-1.4-1.1-1.2-1.1-1.1-1.4-0.40.4-0.7
Reaction time mean0.50.92.01.0-0.8-0.9-0.8-0.8-0.5-0.9-0.9-0.2-1.2-1.0-0.2-1.41.4-1.2
Reaction time mean AUC0.20.41.30.6-0.4-0.4-0.4-0.3-0.2-0.5-0.50.1-0.7-0.60.1-1.11.1-0.9
Median of all reaction times0.50.72.10.8-0.6-0.6-0.7-0.6-0.3-0.7-0.7-0.0-1.0-0.80.0-1.41.4-1.1
Reaction time omissions0.40.61.10.6-1.0-1.0-0.6-0.8-0.9-0.9-0.9-0.8-0.7-0.8-1.0-0.70.7-0.2
Reaction time false alarm rate0.20.30.6-0.30.50.70.20.40.80.50.50.70.40.50.8-0.50.4-0.1
Reaction time premature initiation rate0.50.71.90.6-0.3-0.2-0.6-0.60.4-0.7-0.70.4-1.1-1.00.8-1.21.1-1.4
Reaction time premature initiations1.01.73.41.4-1.1-1.1-1.3-1.4-0.4-1.5-1.4-0.4-1.8-1.70.0-1.41.3-1.9
Std. dev. reaction times1.73.14.51.9-1.8-1.9-1.8-1.8-1.3-1.9-1.8-1.2-2.1-1.9-1.1-1.91.9-1.8
Reaction time trials completed0.71.42.11.3-1.4-1.4-1.2-1.2-1.4-1.4-1.1-1.2-1.1-1.1-1.4-0.40.4-0.7
Reaction time trials AUC0.81.52.21.4-1.4-1.5-1.3-1.3-1.5-1.4-1.2-1.3-1.2-1.2-1.4-0.40.5-0.8
Run reversals in cocaine runway, females1.61.62.51.3-1.2-1.1-1.2-1.5-0.7-1.3-1.4-0.7-1.6-1.5-0.1-1.41.4-1.4
Run reversals in cocaine runway, males2.42.43.3-1.81.61.51.81.71.21.51.71.21.71.80.71.3-1.41.7
Latency to leave start box in cocaine runway1.31.52.9-1.51.20.91.51.41.11.31.40.91.41.70.10.6-0.51.5
Latency to leave start box in cocaine runway, F2.02.33.8-1.81.61.31.71.71.31.61.81.01.72.00.41.2-1.21.7
Latency to leave start box in cocaine runway, M0.10.10.7-0.2-0.2-0.30.20.1-0.0-0.1-0.00.10.00.2-0.6-0.80.80.4
Std. dev. time between licks in bursts0.20.20.5-0.50.40.60.40.60.20.60.20.10.60.30.20.7-0.70.6
Total sessions with >9 infusions3.44.16.32.5-2.1-2.0-2.4-2.3-1.1-2.2-1.9-1.3-2.3-2.2-0.7-2.02.1-2.3
Short access day 1 total inactive lever presses0.40.51.4-0.70.60.30.70.5-0.00.80.6-0.20.80.7-0.20.9-0.91.2
Short access day 10 total inactive lever presses0.10.30.60.5-0.5-0.6-0.3-0.5-0.6-0.6-0.6-0.4-0.8-0.6-0.4-0.60.5-0.1
Short access day 1 total infusions0.30.41.50.7-0.4-0.3-0.6-0.50.2-0.5-0.10.2-0.7-0.40.4-1.11.2-1.2
Short access day 10 total infusions0.40.52.20.7-0.3-0.2-0.5-0.50.7-0.5-0.10.4-0.6-0.40.8-1.11.2-1.5
Short access total infusions0.81.03.21.2-0.8-0.7-1.1-1.00.2-0.9-0.6-0.1-1.2-1.00.5-1.41.3-1.8
ShA early post infusion interval0.90.91.4-1.10.90.81.21.01.00.90.90.80.91.00.40.9-0.91.0
ShA late post infusion interval1.01.03.60.9-0.5-0.3-0.9-0.60.2-0.9-0.20.7-0.8-0.80.7-1.91.8-1.7
ShA early loading0.80.82.2-0.1-0.3-0.4-0.1-0.1-1.10.0-0.4-1.30.2-0.0-1.51.4-1.41.4
ShA late loading0.71.03.5-1.00.60.40.90.7-0.10.80.2-0.40.70.9-0.71.9-1.71.8
Short access day 1 locomotion0.70.83.11.0-0.8-1.0-0.9-0.7-0.1-0.8-0.3-0.1-0.8-0.6-0.4-1.71.8-0.9
Short access day 10 total locomotion1.12.14.21.7-1.5-1.4-1.6-1.5-0.8-1.7-1.1-0.5-1.5-1.4-0.4-1.92.0-1.6
Short access total locomotion2.12.55.61.9-1.5-1.4-1.8-1.6-0.3-1.7-1.0-0.2-1.6-1.4-0.1-2.42.3-2.1
ShA early average infusions3.13.612.6-1.51.00.51.31.2-0.51.50.6-1.01.71.5-1.63.6-3.43.3
ShA late average infusions1.61.66.9-1.00.60.40.80.6-0.20.90.4-0.81.01.0-0.92.6-2.42.1
ShA early timeout1.51.56.3-0.30.1-0.30.10.1-1.10.4-0.4-1.50.60.4-1.72.5-2.41.9
ShA late timeout0.50.52.4-0.50.50.30.40.4-0.10.60.2-0.40.40.7-0.31.5-1.41.1
ShA early titration2.32.59.0-1.30.80.31.11.0-0.51.20.2-1.01.21.1-1.63.0-2.92.8
ShA late titration0.70.84.0-0.30.2-0.10.20.2-0.40.4-0.0-1.00.30.5-0.92.0-1.81.3
ShA total infusions1.72.08.2-1.20.70.41.00.6-0.31.10.3-0.91.11.0-1.22.9-2.62.5
One hour access (0.3 mA shock)0.60.71.60.9-0.9-1.2-0.7-0.8-1.1-0.8-0.8-1.0-0.8-0.7-1.3-0.70.6-0.1
Shock compulsivity0.71.43.11.4-1.0-1.2-1.3-1.5-0.5-1.2-1.3-1.1-1.8-1.4-0.5-0.60.8-1.0
Compulsive drug intake0.40.41.8-0.70.40.30.70.6-0.40.60.3-0.20.70.6-0.70.8-0.91.3
One hour access (shock baseline)0.81.22.31.3-1.0-1.1-1.1-1.1-0.5-1.2-0.8-0.4-1.2-1.0-0.2-1.51.4-1.5
Social response proportion1.82.04.61.5-1.3-1.1-1.4-1.5-0.1-1.4-1.1-0.2-1.7-1.50.3-2.01.8-2.1
Social responses5.06.58.62.8-2.9-2.9-2.6-2.9-2.2-2.9-2.8-2.3-2.9-2.8-2.1-2.01.8-1.9
Social time1.41.93.91.5-1.5-1.4-1.3-1.5-0.5-1.4-1.0-0.6-1.5-1.2-0.4-2.01.8-1.6
Soleus weight3.49.913.93.6-3.1-3.1-3.4-3.1-2.4-3.4-2.9-1.8-3.6-3.2-1.7-3.73.7-3.6
Bone: stiffness2.03.25.42.3-1.9-1.7-2.3-1.9-1.5-2.0-1.7-1.5-2.0-1.9-0.9-1.31.2-2.1
Tibialis anterior weight0.31.02.20.9-1.1-1.0-1.1-0.9-1.5-1.1-1.0-1.2-0.6-0.9-1.40.00.0-0.4
Time to tail flick, vehicle, before self-admin0.50.51.20.7-0.9-0.9-0.6-1.1-0.8-0.8-0.7-1.0-0.7-0.7-0.6-0.00.0-0.3
Time to tail flick, vehicle, after self-admin0.20.31.1-0.40.50.30.40.50.20.60.70.10.70.6-0.11.0-0.70.7
Time to tail flick, test, before self-admin1.21.24.20.30.00.1-0.30.01.4-0.30.11.3-0.7-0.61.5-2.02.1-1.7
Time to tail flick, test, after self-admin1.21.21.91.2-1.3-1.2-1.4-1.3-1.1-1.3-1.2-1.3-1.1-1.2-1.10.2-0.2-0.6
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.10.1-0.10.00.3-0.30.20.0-0.20.40.1-0.80.6-0.50.8
Delta time to tail flick, test, before/after SA1.61.73.61.3-1.4-1.2-1.4-1.6-1.7-1.3-1.3-1.9-1.1-1.1-1.40.7-0.7-0.2
Tibia length1.43.75.32.1-2.0-2.0-2.0-2.2-1.0-2.2-1.9-1.2-2.3-2.1-0.8-2.02.1-2.2
Ambulatory time before self-admin0.30.52.00.00.50.40.10.21.00.20.51.2-0.20.31.4-0.80.6-1.1
Ambulatory time after self-admin0.50.51.6-0.20.40.40.30.31.20.20.61.2-0.10.31.2-0.90.9-1.0
Bone: tissue strength0.30.30.6-0.70.50.40.70.70.20.70.60.30.70.70.00.5-0.50.8
Total heroin consumption1.11.32.71.1-1.3-1.5-1.2-1.2-1.1-1.2-1.3-1.3-1.0-1.2-1.7-0.20.2-0.3
Total infusions0.60.82.60.6-0.6-1.0-0.6-0.7-1.1-0.5-0.8-1.5-0.5-0.4-1.60.9-0.70.6
Bone: trabecular number0.81.43.81.0-1.2-1.1-1.2-1.1-1.9-0.9-1.2-1.7-0.6-0.8-1.80.8-0.80.3
Bone: trabecular spacing0.20.20.4-0.60.50.40.70.50.30.50.50.30.50.50.20.2-0.20.5
Bone: trabecular thickness5.06.38.32.8-2.8-2.8-2.9-2.6-2.9-2.7-2.7-2.8-2.4-2.5-2.8-1.31.3-1.3
Bone: trabecular tissue density0.60.82.41.0-0.6-0.5-0.9-0.70.1-0.8-0.6-0.2-1.1-0.80.4-1.51.5-1.5
Water consumed over 24 hours0.10.20.50.4-0.3-0.3-0.4-0.4-0.1-0.4-0.3-0.0-0.6-0.40.3-0.60.5-0.7
Number of responses in last shaping day0.40.42.00.4-0.3-0.2-0.4-0.40.2-0.4-0.20.5-0.6-0.50.7-1.41.2-1.0