Pavlov. Cond. lever latency

Pavlovian Conditioned Approach, Sign-tracking, average lever latency on days 4 and 5 of testing

Tags: Behavior · Pavlovian conditioned approach · Conditioned reinforcement

Project: p50_paul_meyer_2014

3 loci · 8 genes with independent associations · 206 total associated genes

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr1 154982166 158398949 5 1 2.18e-08 5.53e-08 3.47e-02 Tenm4
2 chr1 160012402 166764537 200 6 2.28e-10 1.00e-09 1.00e+00 LOC120099897 Map6 Plekhb1 Relt Tsku Wnt11
3 chr9 83390749 84777604 1 1 0.00e+00 9.11e-02 1.00e+00 Retreg2

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 3838.58 1 1 12.5 0 1.00e+00 Retreg2
BMI without tail 144009.17 1 1 12.5 0 1.00e+00 Retreg2
Body weight 3.91 1 0 0 0 1.00e+00 Retreg2
Epididymis fat weight 108443.4 1 1 12.5 0 1.00e+00 Retreg2
Glucose 2366.35 1 1 12.5 0 1.00e+00 Retreg2
Heart weight 13509 1 1 12.5 0 1.00e+00 Retreg2
Left kidney weight 141259.46 1 1 12.5 0 1.00e+00 Retreg2
Right kidney weight 116847.14 1 1 12.5 0 1.00e+00 Retreg2
Tail length 92117.69 1 1 12.5 0 1.00e+00 Retreg2
Length with tail 6138.87 1 1 12.5 0 1.00e+00 Retreg2
Length without tail 129313.22 1 1 12.5 0 1.00e+00 Retreg2
Liver weight, left 14514.29 1 1 12.5 0 1.00e+00 Retreg2
Liver weight, right 252.56 1 1 12.5 0 1.00e+00 Retreg2
Parametrial fat weight 615.65 1 1 12.5 0 1.00e+00 Retreg2
Retroperitoneal fat weight 768.18 13 1 12.5 -0.96 1.96e-12 B3gnt6 Capn5 Emsy Gdpd4 LOC134484907 Pgm2l1 Plekhb1 Rab30 Retreg2 Slco2b1 Thap12 Ucp2 Wnt11
Intraocular pressure 40071.91 1 1 12.5 0 1.00e+00 Retreg2
Extensor digitorum longus weight 4682.69 1 1 12.5 0 1.00e+00 Retreg2
Soleus weight 115.65 1 1 12.5 0 1.00e+00 Retreg2
Tibialis anterior weight 4881.94 1 1 12.5 0 1.00e+00 Retreg2
Tibia length 3259.43 1 1 12.5 0 1.00e+00 Retreg2
Number of licking bursts 157119.65 1 1 12.5 0 1.00e+00 Retreg2
Food consumed during 24 hour testing period 106196.53 1 1 12.5 0 1.00e+00 Retreg2
Times rat made contact with spout 305.36 1 1 12.5 0 1.00e+00 Retreg2
Mean time between licks in bursts 199507.71 1 1 12.5 0 1.00e+00 Retreg2
Mean num. licks in bursts 142600.29 1 1 12.5 0 1.00e+00 Retreg2
Std. dev. time between licks in bursts 94042.02 1 1 12.5 0 1.00e+00 Retreg2
Water consumed over 24 hours 103408.69 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging indifference point 0 sec 115003.89 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging indifference point AUC 133114.6 1 1 12.5 0 1.00e+00 Retreg2
Indifference point function ln k 142006.4 1 1 12.5 0 1.00e+00 Retreg2
Indifference point function log k 142006.4 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging total patch changes 0 sec 120264.14 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging total patch changes 12 sec 10848.8 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging total patch changes 18 sec 117768.16 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging total patch changes 24 sec 167090.22 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging total patch changes 6 sec 32639.62 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging time to switch 0 sec 156618.53 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging water rate 0 sec 148807.58 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging water rate 12 sec 53955.53 3 1 12.5 0 1.00e+00 LOC120097342 Retreg2 Tenm4
Patch foraging water rate 18 sec 103280.07 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging water rate 24 sec 4691.77 1 1 12.5 0 1.00e+00 Retreg2
Patch foraging water rate 6 sec 3954.86 1 1 12.5 0 1.00e+00 Retreg2
Locomotor activity 12.34 1 0 0 0 1.00e+00 Retreg2
Locomotor testing distance 89448.55 1 1 12.5 0 1.00e+00 Retreg2
Locomotor testing rearing 152414.81 1 1 12.5 0 1.00e+00 Retreg2
Light reinforcement 1 155242.72 1 1 12.5 0 1.00e+00 Retreg2
Light reinforcement 2 107899.08 1 1 12.5 0 1.00e+00 Retreg2
Reaction time number correct 153465.22 1 1 12.5 0 1.00e+00 Retreg2
Reaction time mean minus median 205810.62 1 1 12.5 0 1.00e+00 Retreg2
Reaction time mean minus median AUC 208396.98 1 1 12.5 0 1.00e+00 Retreg2
Reaction time num false alarms 57075.22 1 1 12.5 0 1.00e+00 Retreg2
Reaction time num false alarms AUC 106496.51 1 1 12.5 0 1.00e+00 Retreg2
Reaction time trials correct on left 153465.22 1 1 12.5 0 1.00e+00 Retreg2
Reaction time trials on left 149991.58 1 1 12.5 0 1.00e+00 Retreg2
Reaction time mean 94380.53 1 1 12.5 0 1.00e+00 Retreg2
Reaction time mean AUC 113341.21 1 1 12.5 0 1.00e+00 Retreg2
Median of all reaction times 31417.12 1 1 12.5 0 1.00e+00 Retreg2
Reaction time omissions 34267.91 1 1 12.5 0 1.00e+00 Retreg2
Reaction time false alarm rate 891.26 1 1 12.5 0 1.00e+00 Retreg2
Reaction time premature initiation rate 36877.02 1 1 12.5 0 1.00e+00 Retreg2
Reaction time premature initiations 138718.63 1 1 12.5 0 1.00e+00 Retreg2
Std. dev. reaction times 149487.71 1 1 12.5 0 1.00e+00 Retreg2
Reaction time trials completed 149991.58 1 1 12.5 0 1.00e+00 Retreg2
Reaction time trials AUC 151696.42 1 1 12.5 0 1.00e+00 Retreg2
Social response proportion 35302.65 1 1 12.5 0 1.00e+00 Retreg2
Social responses 5682.08 1 1 12.5 0 1.00e+00 Retreg2
Social time 44238.34 1 1 12.5 0 1.00e+00 Retreg2
Conditioned locomotion 6074.35 1 1 12.5 0 1.00e+00 Retreg2
Cocaine response after cond. corrected 65812.39 1 1 12.5 0 1.00e+00 Retreg2
Cocaine response after cond. not corrected 64247.35 1 1 12.5 0 1.00e+00 Retreg2
Cocaine response before conditioning 2800.41 1 1 12.5 0 1.00e+00 Retreg2
Saline control response 12962.78 1 1 12.5 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 4460.06 7 1 12.5 0.98 2.42e-08 Fam168a Mrpl48 P2ry6 Plekhb1 Rab6a Relt Retreg2
Condit. Reinf. active-inactive response ratio 91582.24 1 1 12.5 0 1.00e+00 Retreg2
Condit. Reinf. active responses 48.91 53 1 12.5 0.39 4.62e-11 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 Lrrc32 Map6 Mogat2 Mrpl48 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Thap12 Tsku Uvrag Wnt11 Xndc1
Condit. Reinf. inactive responses 21059.35 2 1 12.5 0 1.00e+00 Plekhb1 Retreg2
Condit. Reinf. lever presses 58.82 66 50 625 0.2 4.58e-05 Acer3 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Chrna10 Clpb Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gab2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097342 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Nars2 Numa1 Nup98 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Prcp Rab30 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Tenm4 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Condit. Reinf. lever reinforcers received 19.81 55 2 25 -0.09 8.81e-02 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 Lrrc32 Map6 Mogat2 Mrpl48 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Pavlov. Cond. magazine entry latency 49418.79 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. change in total contacts 290.84 64 20 250 -0.85 1.88e-113 Acer3 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Chrna10 Clpb Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gab2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097342 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Nars2 Numa1 Nup98 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Tenm4 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Pavlov. Cond. index score 131.44 66 5 62.5 -0.92 1.70e-168 Acer3 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Chrna10 Clpb Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gab2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097342 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Nars2 Numa1 Nup98 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Prcp Rab30 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Tenm4 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Pavlov. Cond. latency score 155.2 66 1 12.5 -0.9 5.52e-148 Acer3 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Chrna10 Clpb Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gab2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097342 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Nars2 Numa1 Nup98 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Prcp Rab30 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Tenm4 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Pavlov. Cond. lever contacts 73.87 66 62 775 -0.98 3.94e-295 Acer3 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Chrna10 Clpb Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gab2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097342 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Nars2 Numa1 Nup98 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Prcp Rab30 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Tenm4 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Pavlov. Cond. magazine entry number 741.17 15 1 12.5 1 1.43e-24 Capn5 Chrna10 Clpb Gab2 Gdpd4 LOC120099897 Nars2 Numa1 Nup98 Pde2a Pgap2 Retreg2 Rnf121 Stim1 Tenm4
Pavlov. Cond. intertrial magazine entries 104933.78 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 123.45 65 1 12.5 -0.92 1.79e-169 Acer3 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Chrna10 Clpb Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gab2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Nars2 Numa1 Nup98 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Prcp Rab30 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Tenm4 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Pavlov. Cond. response bias 34.72 66 62 775 -0.98 3.05e-305 Acer3 Anapc15 Arap1 Arhgef17 Arrb1 Art2b Atg16l2 B3gnt6 Capn5 Chrna10 Clpb Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Folr2 Gab2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097342 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Nars2 Numa1 Nup98 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgap2 Pgm2l1 Plekhb1 Ppme1 Prcp Rab30 Rab6a Relt Retreg2 Rhog Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Stim1 Tenm4 Thap12 Tsku Ucp2 Uvrag Wnt11 Xndc1
Conditioned reinforcement - actives 191492.54 1 1 12.5 0 1.00e+00 Retreg2
Conditioned reinforcement - inactives 155032.91 1 1 12.5 0 1.00e+00 Retreg2
Conditioned locomotion 41346.85 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access intake day 1-15 change 210605.99 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access intake escalation 209543.53 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access intake escalation 2 107995.31 1 1 12.5 0 1.00e+00 Retreg2
Intermitt. access day 1 inactive lever presses 236542.72 1 1 12.5 0 1.00e+00 Retreg2
Intermitt. access day 15 inactive lever presses 208241.66 1 1 12.5 0 1.00e+00 Retreg2
Intermitt. access escalation Index 184996.65 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access day 1 total infusions 155525.68 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access day 15 total infusions 131485.34 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access terminal intake (last 3 days) 83205.14 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access total infusions 675.9 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access day 1 locomotion 104459.41 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access day 15 total locomotion 177836.92 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access total locomotion 711.59 1 1 12.5 0 1.00e+00 Retreg2
Intermittent access standard deviation 201906.25 1 1 12.5 0 1.00e+00 Retreg2
Cocaine induced anxiety 160280.46 1 1 12.5 0 1.00e+00 Retreg2
Post-drug Anxiety 20460.83 1 1 12.5 0 1.00e+00 Retreg2
Baseline Anxiety 103471.3 1 1 12.5 0 1.00e+00 Retreg2
Lifetime Intake 6830.03 1 1 12.5 0 1.00e+00 Retreg2
Incentive Sensitization - Responses 163579.25 1 1 12.5 0 1.00e+00 Retreg2
Incentive Sensitization - Breakpoint 142790.8 1 1 12.5 0 1.00e+00 Retreg2
Progressive ratio test 1 active lever presses 99872.69 1 1 12.5 0 1.00e+00 Retreg2
Progressive ratio test 1 breakpoint 96247.61 1 1 12.5 0 1.00e+00 Retreg2
Progressive ratio test 1 inactive lever presses 151100.07 1 1 12.5 0 1.00e+00 Retreg2
Progressive ratio test 2 active lever presses 57222.6 1 1 12.5 0 1.00e+00 Retreg2
Progressive ratio test 2 breakpoint 34975.96 1 1 12.5 0 1.00e+00 Retreg2
Progressive ratio test 2 inactive lever presses 164104.71 1 1 12.5 0 1.00e+00 Retreg2
Total sessions with >9 infusions 7953.9 1 1 12.5 0 1.00e+00 Retreg2
Short access day 1 total inactive lever presses 114392.27 1 1 12.5 0 1.00e+00 Retreg2
Short access day 10 total inactive lever presses 217140.65 1 1 12.5 0 1.00e+00 Retreg2
Short access day 1 total infusions 111479.43 1 1 12.5 0 1.00e+00 Retreg2
Short access day 10 total infusions 76293.54 1 1 12.5 0 1.00e+00 Retreg2
Short access total infusions 33946.03 1 1 12.5 0 1.00e+00 Retreg2
Short access day 1 locomotion 84055.65 1 1 12.5 0 1.00e+00 Retreg2
Short access day 10 total locomotion 181597.84 1 1 12.5 0 1.00e+00 Retreg2
Short access total locomotion 68266.59 1 1 12.5 0 1.00e+00 Retreg2
Compulsive drug intake 65439.45 1 1 12.5 0 1.00e+00 Retreg2
One hour access (0.3 mA shock) 9669.44 1 1 12.5 0 1.00e+00 Retreg2
One hour access (shock baseline) 140263.4 1 1 12.5 0 1.00e+00 Retreg2
Number of responses in last shaping day 51289.19 1 1 12.5 0 1.00e+00 Retreg2
Context. condit. distance diff. score 970.59 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, session 1 14615.25 1 1 12.5 0 1.00e+00 Retreg2
Locomotion distance, session 1 4416.18 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, session 2 9358 1 1 12.5 0 1.00e+00 Retreg2
Locomotion distance, session 2 2393.66 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, session 3 2332.53 1 1 12.5 0 1.00e+00 Retreg2
Locomotion distance, session 3 16615.78 1 1 12.5 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 3 5866.4 1 1 12.5 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 3 12131.92 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, session 7 1310.17 1 1 12.5 0 1.00e+00 Retreg2
Locomotion distance, session 7 3744.54 1 1 12.5 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 7 10466.92 1 1 12.5 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 7 8847.36 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, session 8 1892.98 1 1 12.5 0 1.00e+00 Retreg2
Locomotion distance, session 8 673.32 1 1 12.5 0 1.00e+00 Retreg2
Degree of sensitization distance 15309.16 1 1 12.5 0 1.00e+00 Retreg2
Degree of sensitization stereotypy 8496.38 1 1 12.5 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 4120.78 1 1 12.5 0 1.00e+00 Retreg2
Condit. Reinf. active-inactive response ratio 1097.66 1 1 12.5 0 1.00e+00 Retreg2
Condit. Reinf. active responses 11664.93 1 1 12.5 0 1.00e+00 Retreg2
Condit. Reinf. inactive responses 19375.3 1 1 12.5 0 1.00e+00 Retreg2
Incentive salience index mean 14781.83 1 1 12.5 0 1.00e+00 Retreg2
Condit. Reinf. lever presses 21433.81 1 1 12.5 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 1 41873.03 1 1 12.5 0 1.00e+00 Retreg2
Time in novel zone, hab. session 1 35522.88 1 1 12.5 0 1.00e+00 Retreg2
Total zone transitions, hab. session 1 1818.53 1 1 12.5 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 1 1687 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 1 1131.06 1 1 12.5 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 2 23379.25 1 1 12.5 0 1.00e+00 Retreg2
Time in novel zone, hab. session 2 24924.95 1 1 12.5 0 1.00e+00 Retreg2
Total zone transitions, hab. session 2 280.53 1 1 12.5 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 2 96.8 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 2 145.53 1 1 12.5 0 1.00e+00 Retreg2
Novel to familiar place preference ratio 55508.81 1 1 12.5 0 1.00e+00 Retreg2
Novelty place preference 54383.96 1 1 12.5 0 1.00e+00 Retreg2
Time in novel zone, NPP test 40844.77 1 1 12.5 0 1.00e+00 Retreg2
Total zone transitions, NPP test 8230.03 1 1 12.5 0 1.00e+00 Retreg2
Total locomotion distance, NPP test 7114 1 1 12.5 0 1.00e+00 Retreg2
Locomotion velocity, NPP test 4041.22 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. lever latency 2195.61 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. change in total contacts 4539.35 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. index score 1769.33 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. latency score 1841.19 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. lever contacts 3029.77 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry number 2162.19 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. intertrial magazine entries 524.02 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 1940.27 1 1 12.5 0 1.00e+00 Retreg2
Pavlov. Cond. response bias 2606.99 1 1 12.5 0 1.00e+00 Retreg2
Bone: apparent density 22268.03 1 1 12.5 0 1.00e+00 Retreg2
Bone surface 25125.6 1 1 12.5 0 1.00e+00 Retreg2
Bone volume 33831.7 1 1 12.5 0 1.00e+00 Retreg2
Bone: connectivity density 7098.55 1 1 12.5 0 1.00e+00 Retreg2
Bone: cortical apparent density 45266.32 1 1 12.5 0 1.00e+00 Retreg2
Bone: cortical area 18930.98 1 1 12.5 0 1.00e+00 Retreg2
Bone: cortical porosity 1837.29 1 1 12.5 0 1.00e+00 Retreg2
Bone: cortical porosity 4807.78 1 1 12.5 0 1.00e+00 Retreg2
Bone: cortical thickness 1627.26 1 1 12.5 0 1.00e+00 Retreg2
Bone: cortical thickness 12190.6 1 1 12.5 0 1.00e+00 Retreg2
Bone: cortical tissue density 48453.42 1 1 12.5 0 1.00e+00 Retreg2
Bone: elastic displacement 29626.25 1 1 12.5 0 1.00e+00 Retreg2
Bone: elastic work 1494.59 1 1 12.5 0 1.00e+00 Retreg2
Bone: endosteal estimation 35257.61 1 1 12.5 0 1.00e+00 Retreg2
Bone: endosteal perimeter 44697.39 1 1 12.5 0 1.00e+00 Retreg2
Bone: final force 7031.22 1 1 12.5 0 1.00e+00 Retreg2
Bone: final moment 1042.62 1 1 12.5 0 1.00e+00 Retreg2
Bone: marrow area 37067.95 1 1 12.5 0 1.00e+00 Retreg2
Bone: maximum diameter 24401.62 1 1 12.5 0 1.00e+00 Retreg2
Bone: maximum force 34553.99 1 1 12.5 0 1.00e+00 Retreg2
Bone: maximum moment 24715.64 1 1 12.5 0 1.00e+00 Retreg2
Bone: minimum diameter 17196.64 1 1 12.5 0 1.00e+00 Retreg2
Bone: periosteal estimation 38190.5 1 1 12.5 0 1.00e+00 Retreg2
Bone: periosteal perimeter 43183.28 1 1 12.5 0 1.00e+00 Retreg2
Bone: post-yield work 50847.58 1 1 12.5 0 1.00e+00 Retreg2
Bone: stiffness 35564.91 1 1 12.5 0 1.00e+00 Retreg2
Bone: tissue strength 12264.67 1 1 12.5 0 1.00e+00 Retreg2
Bone: trabecular number 41138.39 1 1 12.5 0 1.00e+00 Retreg2
Bone: trabecular spacing 31287.85 1 1 12.5 0 1.00e+00 Retreg2
Bone: trabecular thickness 33264.33 1 1 12.5 0 1.00e+00 Retreg2
Bone: trabecular tissue density 53620.06 1 1 12.5 0 1.00e+00 Retreg2
Breakpoint value in progressive ratio session 112428.06 1 1 12.5 0 1.00e+00 Retreg2
Distance traveled before self-admin 134013.73 1 1 12.5 0 1.00e+00 Retreg2
Distance traveled after self-admin 100820.36 1 1 12.5 0 1.00e+00 Retreg2
Delta time in closed arm before/after self-admin 1271.86 1 1 12.5 0 1.00e+00 Retreg2
Delta time in open arm before/after self-admin 54811.83 1 1 12.5 0 1.00e+00 Retreg2
Diff in mean of infusions in LGA sessions 108490.77 1 1 12.5 0 1.00e+00 Retreg2
Extinction: sum of active levers before priming 91573.47 1 1 12.5 0 1.00e+00 Retreg2
Active lever presses in extinction session 6 3117.3 1 1 12.5 0 1.00e+00 Retreg2
Delta distance traveled before/after self-admin 12434.77 1 1 12.5 0 1.00e+00 Retreg2
Delta ambulatory time before/after self-admin 96034.01 1 1 12.5 0 1.00e+00 Retreg2
Time in closed arm before self-admin 88239.28 1 1 12.5 0 1.00e+00 Retreg2
Time in closed arm after self-admin 19471.75 1 1 12.5 0 1.00e+00 Retreg2
Time in open arm before self-admin 34587.99 1 1 12.5 0 1.00e+00 Retreg2
Time in open arm after self-admin 1894.09 1 1 12.5 0 1.00e+00 Retreg2
Sum of active levers in priming session hrs 5-6 3877.89 1 1 12.5 0 1.00e+00 Retreg2
Time to tail flick, vehicle, before self-admin 51335.42 1 1 12.5 0 1.00e+00 Retreg2
Time to tail flick, vehicle, after self-admin 118286.85 1 1 12.5 0 1.00e+00 Retreg2
Time to tail flick, test, before self-admin 32803.11 1 1 12.5 0 1.00e+00 Retreg2
Time to tail flick, test, after self-admin 5828.87 1 1 12.5 0 1.00e+00 Retreg2
Delta time to tail flick, vehicle, before/after SA 36533.83 1 1 12.5 0 1.00e+00 Retreg2
Delta time to tail flick, test, before/after SA 56832.34 1 1 12.5 0 1.00e+00 Retreg2
Ambulatory time before self-admin 171079.71 1 1 12.5 0 1.00e+00 Retreg2
Ambulatory time after self-admin 88230.17 1 1 12.5 0 1.00e+00 Retreg2
Total heroin consumption 961.5 1 1 12.5 0 1.00e+00 Retreg2
Area under the delay curve 81605.23 1 1 12.5 0 1.00e+00 Retreg2
Delay disc. indifference point, 0s delay 9477.47 1 1 12.5 0 1.00e+00 Retreg2
Delay disc. indifference point, 16s delay 74803.61 1 1 12.5 0 1.00e+00 Retreg2
Delay disc. indifference point, 2s delay 825.84 1 1 12.5 0 1.00e+00 Retreg2
Delay disc. indifference point, 24s delay 99983.64 1 1 12.5 0 1.00e+00 Retreg2
Delay disc. indifference point, 4s delay 2525.7 1 1 12.5 0 1.00e+00 Retreg2
Delay disc. indifference point, 8s delay 101423.99 1 1 12.5 0 1.00e+00 Retreg2
Delay discount exponential model param 60214.95 1 1 12.5 0 1.00e+00 Retreg2
Delay discount hyperbolic model param 45715.54 1 1 12.5 0 1.00e+00 Retreg2
Fecal boli incidents, locomotor time 1 150160.89 1 1 12.5 0 1.00e+00 Retreg2
Change in fecal boli incidents, locomotor task 23481.3 1 1 12.5 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 1 49255.61 1 1 12.5 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 1 41590.88 1 1 12.5 0 1.00e+00 Retreg2
Total resting periods, locomotor time 1 11802.64 1 1 12.5 0 1.00e+00 Retreg2
Rest time, locomotor task time 1 75951.88 1 1 12.5 0 1.00e+00 Retreg2
Distance moved, locomotor task time 1 159283.67 1 1 12.5 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 1 219061.96 1 1 12.5 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 2 161986.9 1 1 12.5 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 2 174298.32 1 1 12.5 0 1.00e+00 Retreg2
Total resting periods, locomotor time 2 190079.87 1 1 12.5 0 1.00e+00 Retreg2
Rest time, locomotor task time 2 83778.18 1 1 12.5 0 1.00e+00 Retreg2
Distance moved, locomotor task time 2 34268.85 1 1 12.5 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 2 138414.05 1 1 12.5 0 1.00e+00 Retreg2
Weight adjusted by age 161973.18 1 1 12.5 0 1.00e+00 Retreg2
Seeking ratio, delayed vs. immediate footshock 49395.56 1 1 12.5 0 1.00e+00 Retreg2
Locomotion in novel chamber 16301.47 1 1 12.5 0 1.00e+00 Retreg2
Locomotion in novel chamber post-restriction 154642.04 1 1 12.5 0 1.00e+00 Retreg2
Progressive ratio 157894.89 1 1 12.5 0 1.00e+00 Retreg2
Food seeking constrained by brief footshock 7338.76 1 1 12.5 0 1.00e+00 Retreg2
Seeking ratio, punishment vs. effort 118281.2 1 1 12.5 0 1.00e+00 Retreg2
Run reversals in cocaine runway, females 37174.37 1 1 12.5 0 1.00e+00 Retreg2
Run reversals in cocaine runway, males 29861.56 1 1 12.5 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway 58575.8 1 1 12.5 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, F 28379.24 1 1 12.5 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, M 7140.1 1 1 12.5 0 1.00e+00 Retreg2
Co content in liver 4721.74 1 1 12.5 0 1.00e+00 Retreg2
Cu content in liver 162.43 1 1 12.5 0 1.00e+00 Retreg2
Fe content in liver 5656.2 1 1 12.5 0 1.00e+00 Retreg2
K content in liver 6593.53 1 1 12.5 0 1.00e+00 Retreg2
Mg content in liver 24493.99 1 1 12.5 0 1.00e+00 Retreg2
Mn content in liver 4374.36 1 1 12.5 0 1.00e+00 Retreg2
Na content in liver 16641.94 1 1 12.5 0 1.00e+00 Retreg2
Rb content in liver 428.45 1 1 12.5 0 1.00e+00 Retreg2
Zn content in liver 15755.62 1 1 12.5 0 1.00e+00 Retreg2

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 6 0.2 1.34
Adipose alternative TSS 16 0.4 1.45
Adipose gene expression 15 0.2 1.36
Adipose isoform ratio 15 0.3 1.36
Adipose intron excision ratio 5 0.2 1.27
Adipose mRNA stability 11 0.3 1.41
BLA alternative polyA 3 0.1 1.43
BLA alternative TSS 5 0.2 1.43
BLA gene expression 13 0.2 1.39
BLA isoform ratio 4 0.1 1.35
BLA intron excision ratio 3 0.1 1.33
BLA mRNA stability 6 0.2 1.37
Brain alternative polyA 3 0.1 1.32
Brain alternative TSS 7 0.2 1.43
Brain gene expression 13 0.1 1.35
Brain isoform ratio 10 0.2 1.34
Brain intron excision ratio 8 0.1 1.32
Brain mRNA stability 10 0.2 1.37
Eye alternative polyA 2 0.7 1.36
Eye alternative TSS 0 0 1.3
Eye gene expression 2 0.2 1.39
Eye isoform ratio 0 0 1.26
Eye intron excision ratio 1 0.1 1.46
Eye mRNA stability 1 0.3 1.55
IC alternative polyA 2 0.1 1.48
IC alternative TSS 4 0.2 1.35
IC gene expression 14 0.2 1.42
IC isoform ratio 2 0.1 1.39
IC intron excision ratio 6 0.2 1.35
IC mRNA stability 3 0.2 1.31
IL alternative polyA 0 0 1.23
IL alternative TSS 0 0 1.29
IL gene expression 4 0.1 1.37
IL isoform ratio 0 0 1.22
IL intron excision ratio 1 0.1 1.34
IL mRNA stability 1 0.1 1.29
LHb alternative polyA 0 0 1.26
LHb alternative TSS 0 0 1.21
LHb gene expression 1 0 1.37
LHb isoform ratio 0 0 1.19
LHb intron excision ratio 0 0 1.29
LHb mRNA stability 1 0.1 1.34
Liver alternative polyA 4 0.2 1.34
Liver alternative TSS 10 0.3 1.52
Liver gene expression 16 0.2 1.39
Liver isoform ratio 9 0.2 1.38
Liver intron excision ratio 12 0.2 1.41
Liver mRNA stability 5 0.2 1.33
NAcc alternative polyA 3 0.1 5.71
NAcc alternative TSS 13 0.3 1.45
NAcc gene expression 14 0.1 1.39
NAcc isoform ratio 9 0.2 1.34
NAcc intron excision ratio 6 0.1 1.33
NAcc mRNA stability 7 0.2 1.38
OFC alternative polyA 2 0.2 1.41
OFC alternative TSS 0 0 1.32
OFC gene expression 3 0.1 1.37
OFC isoform ratio 2 0.1 1.24
OFC intron excision ratio 0 0 1.27
OFC mRNA stability 0 0 1.34
PL alternative polyA 11 0.3 1.45
PL alternative TSS 4 0.1 1.4
PL gene expression 12 0.1 1.38
PL isoform ratio 11 0.2 1.36
PL intron excision ratio 7 0.1 1.32
PL mRNA stability 7 0.2 1.37
pVTA alternative polyA 4 0.2 1.32
pVTA alternative TSS 11 0.4 1.39
pVTA gene expression 11 0.1 1.36
pVTA isoform ratio 7 0.2 1.28
pVTA intron excision ratio 6 0.1 1.28
pVTA mRNA stability 5 0.2 1.42
RMTg alternative polyA 0 0 1.33
RMTg alternative TSS 1 0.2 1.26
RMTg gene expression 0 0 1.34
RMTg isoform ratio 0 0 1.22
RMTg intron excision ratio 0 0 1.39
RMTg mRNA stability 1 0.2 1.37