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Intermittent access intake day 1-15 change

Intermittent access intake change from day 1 to day 15

Tags: Behavior · Intermittent access · Cocaine

Project: p50_paul_meyer_2020

4 loci · 4 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr8	41432021	42517271	1	1	3.80e-18	4.36e-03	8.37e-03	Foxred1
2	chr9	83390749	84777604	2	1	0.00e+00	3.43e-02	1.00e+00	Retreg2
3	chr17	56581483	57955699	1	1	3.97e-11	1.94e-01	1.00e+00	LOC108348573
4	chr17	61510864	62906219	1	1	2.70e-10	2.02e-01	2.09e-11	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1920.83	2	1	25	0	1.00e+00	Foxred1 Retreg2
BMI without tail	48016.73	2	2	50	0	1.00e+00	Ccny Retreg2
Body weight	3.91	1	0	0	0	1.00e+00	Retreg2
Epididymis fat weight	36173.48	2	2	50	0	1.00e+00	Ccny Retreg2
Glucose	2366.35	1	1	25	0	1.00e+00	Retreg2
Heart weight	6763.89	2	2	50	0	1.00e+00	Ccny Retreg2
Left kidney weight	28255.52	4	1	25	-1	1.76e-06	Ccny Foxred1 LOC108348573 Retreg2
Right kidney weight	29218.45	3	2	50	-1	1.09e-04	Ccny Foxred1 Retreg2
Tail length	23038.61	3	2	50	1	1.17e-05	Ccny LOC108348573 Retreg2
Length with tail	1536.79	3	1	25	1	3.09e-04	Foxred1 LOC108348573 Retreg2
Length without tail	43114.79	2	2	50	0	1.00e+00	Ccny Retreg2
Liver weight, left	7265.45	2	2	50	0	1.00e+00	Ccny Retreg2
Liver weight, right	129.69	2	1	25	0	1.00e+00	Ccny Retreg2
Parametrial fat weight	157.57	3	1	25	1	6.45e-04	Ccny Foxred1 Retreg2
Retroperitoneal fat weight	8031.71	1	1	25	0	1.00e+00	Retreg2
Intraocular pressure	20040.92	1	1	25	0	1.00e+00	Retreg2
Extensor digitorum longus weight	4682.69	1	1	25	0	1.00e+00	Retreg2
Soleus weight	59.13	2	1	25	0	1.00e+00	Ccny Retreg2
Tibialis anterior weight	4881.94	1	1	25	0	1.00e+00	Retreg2
Tibia length	3259.43	1	1	25	0	1.00e+00	Retreg2
Number of licking bursts	52378.83	2	1	25	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	35405.76	2	1	25	0	1.00e+00	Ccny Retreg2
Times rat made contact with spout	305.36	1	1	25	0	1.00e+00	Retreg2
Mean time between licks in bursts	66505.9	2	1	25	0	1.00e+00	Ccny Retreg2
Mean num. licks in bursts	47539.71	2	1	25	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	47023.26	1	1	25	0	1.00e+00	Retreg2
Water consumed over 24 hours	34477.35	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	44400.63	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function ln k	47362.28	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function log k	47362.28	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 0 sec	40089.81	2	1	25	0	1.00e+00	Foxred1 Retreg2
Patch foraging total patch changes 12 sec	3670.27	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Patch foraging total patch changes 18 sec	39260.23	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 24 sec	55706.51	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 6 sec	16352.42	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging time to switch 0 sec	78317.03	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	74409.78	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	53974.31	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	34430.86	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 24 sec	2357.13	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 6 sec	2028.63	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotor activity	26.33	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Locomotor testing distance	22395.94	3	2	50	-1	7.65e-04	Ccny Foxred1 Retreg2
Locomotor testing rearing	50814.92	2	1	25	0	1.00e+00	Foxred1 Retreg2
Light reinforcement 1	51785.62	2	2	50	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	36018.13	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time number correct	51169.82	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	68610.76	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median AUC	104208.6	1	1	25	0	1.00e+00	Retreg2
Reaction time num false alarms	28557.11	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time num false alarms AUC	35512.89	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	51169.82	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	50015.01	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean	31467.08	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean AUC	37788.22	2	1	25	0	1.00e+00	Ccny Retreg2
Median of all reaction times	15714.05	1	1	25	0	1.00e+00	Retreg2
Reaction time omissions	17136.41	1	1	25	0	1.00e+00	Retreg2
Reaction time false alarm rate	891.26	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiation rate	18442.81	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	46245.52	2	1	25	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	74752.64	1	1	25	0	1.00e+00	Retreg2
Reaction time trials completed	50015.01	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	50583.83	2	2	50	0	1.00e+00	Ccny Retreg2
Social response proportion	35302.65	1	1	25	0	1.00e+00	Retreg2
Social responses	2856.43	2	2	50	0	1.00e+00	Ccny Retreg2
Social time	22121.54	2	1	25	0	1.00e+00	Ccny Retreg2
Conditioned locomotion	3044.63	2	1	25	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	21948.64	2	1	25	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. not corrected	21423.84	2	1	25	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	1409.02	2	1	25	0	1.00e+00	Ccny Retreg2
Saline control response	6484.47	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	9691.24	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	15873.43	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	24714.14	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. change in total contacts	57394.24	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	23998.4	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. latency score	29242.48	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	52471.02	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22438.69	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. response bias	5169.79	1	1	25	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	63840.11	2	2	50	0	1.00e+00	Ccny Retreg2
Conditioned reinforcement - inactives	38768.74	3	2	50	1	1.37e-04	Ccny Foxred1 Retreg2
Conditioned locomotion	13824.85	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access intake escalation	52398.96	3	3	75	1	7.74e-06	Foxred1 LOC108348573 Retreg2
Intermittent access intake escalation 2	27054.07	4	4	100	1	1.05e-03	Ccny Foxred1 LOC108348573 Retreg2
Intermitt. access day 1 inactive lever presses	78854.06	2	1	25	0	1.00e+00	Ccny Retreg2
Intermitt. access day 15 inactive lever presses	52070.2	3	2	50	1	2.76e-06	Foxred1 LOC108348573 Retreg2
Intermitt. access escalation Index	61671.96	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 total infusions	31110.56	4	1	25	-1	5.23e-08	Ccny Foxred1 LOC108348573 Retreg2
Intermittent access day 15 total infusions	26308.33	4	2	50	1	1.66e-07	Ccny Foxred1 LOC108348573 Retreg2
Intermittent access terminal intake (last 3 days)	20812.16	3	2	50	1	6.74e-05	Ccny Foxred1 Retreg2
Intermittent access total infusions	234.73	3	1	25	0	1.00e+00	Ccny Foxred1 Retreg2
Intermittent access day 1 locomotion	26127.93	3	2	50	-1	2.84e-04	Ccny Foxred1 Retreg2
Intermittent access day 15 total locomotion	44477.27	3	2	50	1	5.71e-05	Ccny LOC108348573 Retreg2
Intermittent access total locomotion	711.59	1	1	25	0	1.00e+00	Retreg2
Intermittent access standard deviation	40395.61	4	2	50	1	4.45e-06	Ccny Foxred1 LOC108348573 Retreg2
Cocaine induced anxiety	40081.45	3	2	50	-1	1.58e-04	Ccny Foxred1 Retreg2
Post-drug Anxiety	10234.13	1	1	25	0	1.00e+00	Retreg2
Baseline Anxiety	25888.27	3	2	50	1	4.15e-04	Ccny Foxred1 Retreg2
Lifetime Intake	2296.41	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Incentive Sensitization - Responses	54538.9	2	2	50	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Breakpoint	35708.07	3	2	50	-1	1.37e-04	Ccny Foxred1 Retreg2
Progressive ratio test 1 active lever presses	24988.28	3	2	50	1	4.02e-04	Ccny LOC108348573 Retreg2
Progressive ratio test 1 breakpoint	24080.92	3	2	50	1	3.80e-04	Ccny LOC108348573 Retreg2
Progressive ratio test 1 inactive lever presses	37782.8	3	2	50	1	9.86e-05	Ccny Foxred1 Retreg2
Progressive ratio test 2 active lever presses	19092.21	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 breakpoint	8763.02	3	2	50	-1	3.15e-04	Ccny LOC108348573 Retreg2
Progressive ratio test 2 inactive lever presses	41035.17	3	2	50	1	1.10e-04	Ccny Foxred1 Retreg2
Total sessions with >9 infusions	4022.32	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 total inactive lever presses	28606.45	3	2	50	-1	1.48e-04	Ccny Foxred1 Retreg2
Short access day 10 total inactive lever presses	54317.18	3	2	50	1	5.04e-04	Ccny LOC108348573 Retreg2
Short access day 1 total infusions	27935.77	3	2	50	-1	1.08e-03	Ccny Foxred1 Retreg2
Short access day 10 total infusions	19078.96	3	1	25	-1	2.92e-05	Ccny LOC108348573 Retreg2
Short access total infusions	17026.24	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	21032.66	3	2	50	1	3.77e-04	Ccny Foxred1 Retreg2
Short access day 10 total locomotion	45410.93	3	3	75	1	1.45e-04	Ccny Foxred1 Retreg2
Short access total locomotion	22766.87	2	2	50	0	1.00e+00	Foxred1 Retreg2
Compulsive drug intake	16369.35	3	2	50	-1	2.98e-04	Ccny Foxred1 Retreg2
One hour access (0.3 mA shock)	2446.42	4	3	75	0.99	7.45e-03	Ccny Foxred1 LOC108348573 Retreg2
One hour access (shock baseline)	35072.97	3	1	25	1	1.20e-06	Ccny Foxred1 Retreg2
Number of responses in last shaping day	12857.48	3	2	50	1	6.45e-04	Ccny Foxred1 Retreg2
Context. condit. distance diff. score	488.1	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	14615.25	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 1	2213.01	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	9358	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 2	1206.44	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	2332.53	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 7	3744.54	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 8	950.4	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	8496.38	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	2066.34	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	5839.15	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. inactive responses	19375.3	1	1	25	0	1.00e+00	Retreg2
Incentive salience index mean	7397.37	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	21433.81	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	20942.04	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	17764.8	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	25	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	11692.92	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	12466.52	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	280.53	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	77.91	2	1	25	0	1.00e+00	Ccny Retreg2
Novel to familiar place preference ratio	18508.59	2	1	25	0	1.00e+00	Ccny Retreg2
Novelty place preference	27195.73	2	1	25	0	1.00e+00	Ccny Retreg2
Time in novel zone, NPP test	40844.77	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, NPP test	8230.03	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	3566.83	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion velocity, NPP test	2031.76	2	2	50	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	2195.61	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	8.04	1	0	0	0	1.00e+00	Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	1769.33	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	1841.19	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	3029.77	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	1086.53	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. intertrial magazine entries	524.02	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	2606.99	1	1	25	0	1.00e+00	Retreg2
Bone: apparent density	22268.03	1	1	25	0	1.00e+00	Retreg2
Bone surface	25125.6	1	1	25	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	25	0	1.00e+00	Retreg2
Bone: connectivity density	7098.55	1	1	25	0	1.00e+00	Retreg2
Bone: cortical apparent density	22635.68	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: cortical area	18930.98	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	1837.29	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	4807.78	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	1627.26	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	12190.6	1	1	25	0	1.00e+00	Retreg2
Bone: cortical tissue density	24229.43	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: elastic displacement	14817.48	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal estimation	35257.61	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal perimeter	22350.62	1	1	25	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	25	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	25	0	1.00e+00	Retreg2
Bone: marrow area	37067.95	1	1	25	0	1.00e+00	Retreg2
Bone: maximum diameter	24401.62	1	1	25	0	1.00e+00	Retreg2
Bone: maximum force	34553.99	1	1	25	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	25	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal perimeter	21593.38	1	1	25	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	25	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	25	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular spacing	31287.85	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular thickness	33264.33	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular tissue density	26819.29	2	2	50	0	1.00e+00	Ccny Retreg2
Breakpoint value in progressive ratio session	28118.97	3	2	50	1	1.19e-04	Ccny LOC108348573 Retreg2
Distance traveled before self-admin	33524.56	3	2	50	1	3.44e-04	Ccny Foxred1 Retreg2
Distance traveled after self-admin	33650.45	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Delta time in closed arm before/after self-admin	696.27	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Delta time in open arm before/after self-admin	18299.4	2	2	50	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	54251.33	1	1	25	0	1.00e+00	Retreg2
Extinction: sum of active levers before priming	18359.03	4	3	75	1	2.08e-05	Ccny Foxred1 LOC108348573 Retreg2
Active lever presses in extinction session 6	841.94	4	2	50	-0.95	5.10e-02	Ccny Foxred1 LOC108348573 Retreg2
Delta distance traveled before/after self-admin	3150.59	3	2	50	-0.99	5.83e-03	Ccny Foxred1 Retreg2
Delta ambulatory time before/after self-admin	24034.38	3	2	50	-1	5.57e-04	Ccny Foxred1 Retreg2
Time in closed arm before self-admin	22073.91	3	2	50	-1	1.44e-04	Ccny Foxred1 Retreg2
Time in closed arm after self-admin	9901.19	2	2	50	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	11580.26	2	2	50	0	1.00e+00	Ccny Retreg2
Time in open arm after self-admin	657.22	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Sum of active levers in priming session hrs 5-6	1955.23	2	2	50	0	1.00e+00	LOC108348573 Retreg2
Time to tail flick, vehicle, before self-admin	12969.27	3	2	50	1	3.41e-03	Ccny Foxred1 Retreg2
Time to tail flick, vehicle, after self-admin	29586.65	3	2	50	1	2.84e-04	Ccny Foxred1 Retreg2
Time to tail flick, test, before self-admin	8209.31	4	1	25	-1	1.02e-03	Ccny Foxred1 LOC108348573 Retreg2
Time to tail flick, test, after self-admin	1503.42	4	2	50	0.99	1.28e-02	Ccny Foxred1 LOC108348573 Retreg2
Delta time to tail flick, vehicle, before/after SA	9231.19	3	2	50	0.99	5.48e-03	Ccny LOC108348573 Retreg2
Delta time to tail flick, test, before/after SA	28423.85	2	1	25	0	1.00e+00	Ccny Retreg2
Ambulatory time before self-admin	34236.42	4	3	75	1	6.13e-06	Ccny Foxred1 LOC108348573 Retreg2
Ambulatory time after self-admin	29438.81	3	2	50	0	1.00e+00	Ccny LOC108348573 Retreg2
Total heroin consumption	284.85	4	3	75	0.9	9.81e-02	Ccny Foxred1 LOC108348573 Retreg2
Area under the delay curve	20412.63	3	2	50	-1	1.88e-04	Ccny LOC108348573 Retreg2
Delay disc. indifference point, 0s delay	3164.93	3	1	25	0	1.00e+00	Ccny LOC108348573 Retreg2
Delay disc. indifference point, 16s delay	18721.94	3	2	50	-1	5.85e-04	Ccny LOC108348573 Retreg2
Delay disc. indifference point, 2s delay	281.39	3	1	25	0	1.00e+00	Ccny LOC108348573 Retreg2
Delay disc. indifference point, 24s delay	25018.54	3	3	75	-1	3.55e-04	Ccny LOC108348573 Retreg2
Delay disc. indifference point, 4s delay	869.04	3	2	50	0	1.00e+00	Ccny LOC108348573 Retreg2
Delay disc. indifference point, 8s delay	33814.75	2	1	25	0	1.00e+00	LOC108348573 Retreg2
Delay discount exponential model param	15062.55	3	2	50	1	1.54e-04	Ccny LOC108348573 Retreg2
Delay discount hyperbolic model param	15247.61	2	1	25	0	1.00e+00	LOC108348573 Retreg2
Fecal boli incidents, locomotor time 1	50060.01	2	1	25	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	11821.21	2	2	50	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	16440.34	2	2	50	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 1	20842.46	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	5936.78	2	2	50	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	25324.16	2	1	25	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 1	53105.68	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 1	109540.42	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	53999.89	2	1	25	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	43586.58	3	2	50	1	1.48e-04	Ccny Foxred1 Retreg2
Total resting periods, locomotor time 2	47530.19	3	2	50	1	1.13e-04	Ccny Foxred1 Retreg2
Rest time, locomotor task time 2	27936.47	2	2	50	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	46160.97	2	2	50	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	40515.99	3	2	50	1	9.82e-05	Ccny LOC108348573 Retreg2
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	5443	3	2	50	0	1.00e+00	Ccny LOC108348573 Retreg2
Locomotion in novel chamber post-restriction	51552.82	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio	39490	3	2	50	-1	7.09e-05	Ccny LOC108348573 Retreg2
Food seeking constrained by brief footshock	7338.76	1	1	25	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	29576.21	3	2	50	1	2.20e-05	Ccny LOC108348573 Retreg2
Run reversals in cocaine runway, females	9308.37	4	1	25	-1	4.70e-05	Ccny Foxred1 LOC108348573 Retreg2
Run reversals in cocaine runway, males	7476.43	3	1	25	1	8.70e-04	Ccny Foxred1 Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	50	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	2453.48	3	2	50	0	1.00e+00	Ccny Foxred1 Retreg2
Co content in liver	4721.74	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	162.43	1	1	25	0	1.00e+00	Retreg2
Fe content in liver	5656.2	1	1	25	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	25	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	25	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	25	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	25	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	25	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.05
Adipose	alternative TSS	0	0	0.98
Adipose	gene expression	1	0	1.06
Adipose	isoform ratio	0	0	0.98
Adipose	intron excision ratio	0	0	0.89
Adipose	mRNA stability	0	0	1.04
BLA	alternative polyA	0	0	0.99
BLA	alternative TSS	0	0	1.05
BLA	gene expression	0	0	1.06
BLA	isoform ratio	0	0	1.04
BLA	intron excision ratio	0	0	0.97
BLA	mRNA stability	0	0	1.06
Brain	alternative polyA	0	0	1
Brain	alternative TSS	0	0	1.01
Brain	gene expression	0	0	1.06
Brain	isoform ratio	0	0	1.04
Brain	intron excision ratio	0	0	0.99
Brain	mRNA stability	0	0	1.04
Eye	alternative polyA	0	0	1.12
Eye	alternative TSS	0	0	1.26
Eye	gene expression	0	0	1.08
Eye	isoform ratio	0	0	1.01
Eye	intron excision ratio	0	0	0.98
Eye	mRNA stability	0	0	1.08
IC	alternative polyA	0	0	0.98
IC	alternative TSS	0	0	1.04
IC	gene expression	0	0	1.09
IC	isoform ratio	0	0	1
IC	intron excision ratio	0	0	0.96
IC	mRNA stability	0	0	1.05
IL	alternative polyA	0	0	0.94
IL	alternative TSS	0	0	1.09
IL	gene expression	0	0	1.07
IL	isoform ratio	0	0	1.05
IL	intron excision ratio	0	0	0.89
IL	mRNA stability	0	0	1.05
LHb	alternative polyA	0	0	0.89
LHb	alternative TSS	0	0	0.98
LHb	gene expression	0	0	1.05
LHb	isoform ratio	0	0	0.94
LHb	intron excision ratio	0	0	0.89
LHb	mRNA stability	0	0	1.1
Liver	alternative polyA	0	0	1.04
Liver	alternative TSS	0	0	0.97
Liver	gene expression	0	0	1.03
Liver	isoform ratio	0	0	1.02
Liver	intron excision ratio	0	0	0.95
Liver	mRNA stability	0	0	1.04
NAcc	alternative polyA	2	0.1	323.64
NAcc	alternative TSS	0	0	1.05
NAcc	gene expression	0	0	1.08
NAcc	isoform ratio	0	0	1.03
NAcc	intron excision ratio	1	0	1.03
NAcc	mRNA stability	0	0	1.09
OFC	alternative polyA	0	0	1
OFC	alternative TSS	0	0	1.1
OFC	gene expression	0	0	1.07
OFC	isoform ratio	0	0	1.01
OFC	intron excision ratio	0	0	0.95
OFC	mRNA stability	0	0	1.08
PL	alternative polyA	0	0	1
PL	alternative TSS	0	0	1.08
PL	gene expression	0	0	1.09
PL	isoform ratio	0	0	1.04
PL	intron excision ratio	0	0	0.96
PL	mRNA stability	0	0	1.06
pVTA	alternative polyA	0	0	1.01
pVTA	alternative TSS	0	0	1.01
pVTA	gene expression	1	0	1.05
pVTA	isoform ratio	0	0	1.03
pVTA	intron excision ratio	0	0	1
pVTA	mRNA stability	0	0	1.04
RMTg	alternative polyA	0	0	0.93
RMTg	alternative TSS	0	0	0.91
RMTg	gene expression	0	0	1.02
RMTg	isoform ratio	0	0	0.93
RMTg	intron excision ratio	0	0	0.89
RMTg	mRNA stability	0	0	1.02