Hub : Traits

Time to tail flick, vehicle, before self-admin

Time in sec to remove tail from noxious stimuli under vehicle conditions in the first tail flick before self admin

Tags: Behavior · Heroin

Project: u01_peter_kalivas

4 loci · 5 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr2	25579640	27715235	2	2	1.70e-09	7.46e-04	1.35e-04	Homer1 Lhfpl2
2	chr4	97220462	98544003	1	1	8.87e-08	8.29e-02	1.00e+00	Il12rb2
3	chr9	83390749	84777604	1	1	0.00e+00	3.47e-01	1.00e+00	Retreg2
4	chr17	61510864	62906219	1	1	4.00e-143	5.48e-02	1.00e+00	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1923.57	2	2	40	0	1.00e+00	Il12rb2 Retreg2
BMI without tail	48010.36	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Body weight	3.91	1	0	0	0	1.00e+00	Retreg2
Epididymis fat weight	54253.01	2	2	40	0	1.00e+00	Ccny Retreg2
Glucose	2366.35	1	1	20	0	1.00e+00	Retreg2
Heart weight	4510.8	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Left kidney weight	35316.49	4	1	20	-1	4.25e-03	Ccny Il12rb2 Lhfpl2 Retreg2
Right kidney weight	58431.64	2	2	40	0	1.00e+00	Ccny Retreg2
Tail length	46066.56	2	2	40	0	1.00e+00	Ccny Retreg2
Length with tail	3070.71	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Length without tail	64667	2	2	40	0	1.00e+00	Ccny Retreg2
Liver weight, left	7265.45	2	2	40	0	1.00e+00	Ccny Retreg2
Liver weight, right	129.69	2	1	20	0	1.00e+00	Ccny Retreg2
Parametrial fat weight	311.74	2	1	20	0	1.00e+00	Ccny Retreg2
Retroperitoneal fat weight	8029.21	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Intraocular pressure	40071.91	1	1	20	0	1.00e+00	Retreg2
Extensor digitorum longus weight	4682.69	1	1	20	0	1.00e+00	Retreg2
Soleus weight	59.13	2	1	20	0	1.00e+00	Ccny Retreg2
Tibialis anterior weight	4881.94	1	1	20	0	1.00e+00	Retreg2
Tibia length	3259.43	1	1	20	0	1.00e+00	Retreg2
Number of licking bursts	78561.42	2	1	20	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	53104.21	2	1	20	0	1.00e+00	Ccny Retreg2
Times rat made contact with spout	305.36	1	1	20	0	1.00e+00	Retreg2
Mean time between licks in bursts	99755.05	2	1	20	0	1.00e+00	Ccny Retreg2
Mean num. licks in bursts	71302.54	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	94042.02	1	1	20	0	1.00e+00	Retreg2
Water consumed over 24 hours	51711.02	2	1	20	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	57516.69	2	2	40	0	1.00e+00	Il12rb2 Retreg2
Patch foraging indifference point AUC	66593.63	2	2	40	0	1.00e+00	Ccny Retreg2
Indifference point function ln k	71038.09	2	2	40	0	1.00e+00	Ccny Retreg2
Indifference point function log k	71038.09	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 0 sec	60146.55	2	2	40	0	1.00e+00	Il12rb2 Retreg2
Patch foraging total patch changes 12 sec	5502.59	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 18 sec	58887.78	2	1	20	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 24 sec	55704.62	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Patch foraging total patch changes 6 sec	10907.6	3	3	60	0	1.00e+00	Ccny Il12rb2 Retreg2
Patch foraging time to switch 0 sec	156618.53	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	80953.12	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	34430.07	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Patch foraging water rate 24 sec	2357.13	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 6 sec	2028.63	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotor activity	26.25	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotor testing distance	29854.76	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotor testing rearing	76208.8	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Light reinforcement 1	77669.42	2	2	40	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	36016.31	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Reaction time number correct	76747.74	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	102906.71	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median AUC	208396.98	1	1	20	0	1.00e+00	Retreg2
Reaction time num false alarms	28557.11	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time num false alarms AUC	53265.52	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	76747.74	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	75015.72	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time mean	31463.57	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Reaction time mean AUC	37784.58	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Median of all reaction times	15711.8	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Reaction time omissions	34267.91	1	1	20	0	1.00e+00	Retreg2
Reaction time false alarm rate	891.26	1	1	20	0	1.00e+00	Retreg2
Reaction time premature initiation rate	18442.81	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	69362.16	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	74746.04	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Reaction time trials completed	75015.72	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	75869.15	2	2	40	0	1.00e+00	Ccny Retreg2
Social response proportion	17656.73	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Social responses	1909.49	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Social time	22121.54	2	1	20	0	1.00e+00	Ccny Retreg2
Conditioned locomotion	3044.63	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	32913.12	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. not corrected	32126.2	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	942.16	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Saline control response	12962.78	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	9691.24	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	15873.43	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	24714.14	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. change in total contacts	114781.94	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. index score	23998.4	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. latency score	29242.48	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	104933.78	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22438.69	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. response bias	5169.79	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	95753.16	2	2	40	0	1.00e+00	Ccny Retreg2
Conditioned reinforcement - inactives	51686.17	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Conditioned locomotion	20734.34	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access intake day 1-15 change	42123.68	5	2	40	0.99	5.41e-04	Ccny Homer1 Il12rb2 Lhfpl2 Retreg2
Intermittent access intake escalation	69848.84	3	1	20	0	1.00e+00	Homer1 Lhfpl2 Retreg2
Intermittent access intake escalation 2	27027.75	4	2	40	0.99	9.01e-03	Ccny Homer1 Il12rb2 Retreg2
Intermitt. access day 1 inactive lever presses	118272.07	2	1	20	0	1.00e+00	Ccny Retreg2
Intermitt. access day 15 inactive lever presses	208241.66	1	1	20	0	1.00e+00	Retreg2
Intermitt. access escalation Index	61669.62	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Intermittent access day 1 total infusions	77765.06	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total infusions	43834.02	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Intermittent access terminal intake (last 3 days)	27741.87	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Intermittent access total infusions	237.98	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Intermittent access day 1 locomotion	34832.88	3	2	40	0	1.00e+00	Ccny Homer1 Retreg2
Intermittent access day 15 total locomotion	88947.95	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	362.3	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Intermittent access standard deviation	67319.95	3	2	40	0	1.00e+00	Ccny Homer1 Retreg2
Cocaine induced anxiety	40076.14	4	2	40	-1	4.25e-03	Ccny Il12rb2 Lhfpl2 Retreg2
Post-drug Anxiety	10237.65	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Baseline Anxiety	51769.43	2	2	40	0	1.00e+00	Ccny Retreg2
Lifetime Intake	2298.66	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Incentive Sensitization - Responses	81797.54	2	2	40	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Breakpoint	71404.4	2	2	40	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 active lever presses	49966.26	2	2	40	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 breakpoint	48151.76	2	2	40	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 inactive lever presses	50372.47	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Progressive ratio test 2 active lever presses	28633.56	2	2	40	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 breakpoint	17520.06	2	2	40	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 inactive lever presses	54708.36	3	2	40	0	1.00e+00	Ccny Lhfpl2 Retreg2
Total sessions with >9 infusions	2683.7	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Short access day 1 total inactive lever presses	38142.59	3	3	60	0	1.00e+00	Ccny Il12rb2 Retreg2
Short access day 10 total inactive lever presses	72417.01	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Short access day 1 total infusions	37251	3	3	60	0	1.00e+00	Ccny Il12rb2 Retreg2
Short access day 10 total infusions	38150.26	2	1	20	0	1.00e+00	Ccny Retreg2
Short access total infusions	11354.15	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Short access day 1 locomotion	42054.78	2	2	40	0	1.00e+00	Ccny Retreg2
Short access day 10 total locomotion	60537.02	3	2	40	0	1.00e+00	Ccny Homer1 Retreg2
Short access total locomotion	68266.59	1	1	20	0	1.00e+00	Retreg2
Compulsive drug intake	21818.44	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
One hour access (0.3 mA shock)	2435.04	4	2	40	0.98	1.85e-02	Ccny Il12rb2 Lhfpl2 Retreg2
One hour access (shock baseline)	46758.11	3	1	20	0	1.00e+00	Ccny Lhfpl2 Retreg2
Number of responses in last shaping day	17144.55	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Context. condit. distance diff. score	488.1	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	7312.87	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Locomotion distance, session 1	1479.21	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, session 2	9358	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 2	809.89	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, session 3	2332.53	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 7	3744.54	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 8	950.4	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	8496.38	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	2066.34	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	5839.15	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. inactive responses	19375.3	1	1	20	0	1.00e+00	Retreg2
Incentive salience index mean	7397.37	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	21433.81	1	1	20	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	35522.88	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	20	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	567.95	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, hab. session 1	383.06	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	24924.95	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	143.63	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	53.75	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Novel to familiar place preference ratio	27759.88	2	1	20	0	1.00e+00	Ccny Retreg2
Novelty place preference	27195.73	2	1	20	0	1.00e+00	Ccny Retreg2
Time in novel zone, NPP test	40844.77	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, NPP test	4119.07	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Total locomotion distance, NPP test	2380.74	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, NPP test	1357.92	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Pavlov. Cond. lever latency	1100.75	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Pavlov. Cond. magazine entry latency	8.04	1	0	0	0	1.00e+00	Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	1769.33	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	1841.19	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	1517.91	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Pavlov. Cond. magazine entry number	1086.53	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. intertrial magazine entries	524.02	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	2606.99	1	1	20	0	1.00e+00	Retreg2
Bone: apparent density	22268.03	1	1	20	0	1.00e+00	Retreg2
Bone surface	25125.6	1	1	20	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	20	0	1.00e+00	Retreg2
Bone: connectivity density	7098.55	1	1	20	0	1.00e+00	Retreg2
Bone: cortical apparent density	22635.68	2	1	20	0	1.00e+00	Ccny Retreg2
Bone: cortical area	18930.98	1	1	20	0	1.00e+00	Retreg2
Bone: cortical porosity	1837.29	1	1	20	0	1.00e+00	Retreg2
Bone: cortical porosity	4807.78	1	1	20	0	1.00e+00	Retreg2
Bone: cortical thickness	1627.26	1	1	20	0	1.00e+00	Retreg2
Bone: cortical thickness	12190.6	1	1	20	0	1.00e+00	Retreg2
Bone: cortical tissue density	24229.43	2	1	20	0	1.00e+00	Ccny Retreg2
Bone: elastic displacement	29626.25	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	20	0	1.00e+00	Retreg2
Bone: endosteal estimation	35257.61	1	1	20	0	1.00e+00	Retreg2
Bone: endosteal perimeter	44697.39	1	1	20	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	20	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	20	0	1.00e+00	Retreg2
Bone: marrow area	37067.95	1	1	20	0	1.00e+00	Retreg2
Bone: maximum diameter	24401.62	1	1	20	0	1.00e+00	Retreg2
Bone: maximum force	34553.99	1	1	20	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	20	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal perimeter	43183.28	1	1	20	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	20	0	1.00e+00	Retreg2
Bone: stiffness	17784.33	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Bone: tissue strength	12264.67	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular spacing	15646.36	2	1	20	0	1.00e+00	Lhfpl2 Retreg2
Bone: trabecular thickness	33264.33	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular tissue density	26819.29	2	2	40	0	1.00e+00	Ccny Retreg2
Breakpoint value in progressive ratio session	56221.29	2	1	20	0	1.00e+00	Ccny Retreg2
Distance traveled before self-admin	44694.39	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Distance traveled after self-admin	50469.31	2	2	40	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	519.93	4	2	40	0.93	6.92e-02	Ccny Il12rb2 Lhfpl2 Retreg2
Delta time in open arm before/after self-admin	27441.91	2	2	40	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	54247.65	2	1	20	0	1.00e+00	Lhfpl2 Retreg2
Extinction: sum of active levers before priming	30585.52	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Active lever presses in extinction session 6	675.11	5	2	40	-0.91	2.98e-02	Ccny Homer1 Il12rb2 Lhfpl2 Retreg2
Delta distance traveled before/after self-admin	4198.66	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Delta ambulatory time before/after self-admin	32040.15	3	3	60	0	1.00e+00	Ccny Il12rb2 Retreg2
Time in closed arm before self-admin	17664.06	5	3	60	-1	4.15e-04	Ccny Homer1 Il12rb2 Lhfpl2 Retreg2
Time in closed arm after self-admin	9901.19	2	2	40	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	11579.68	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Time in open arm after self-admin	658.77	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Sum of active levers in priming session hrs 5-6	1971.15	2	2	40	0	1.00e+00	Il12rb2 Retreg2
Time to tail flick, vehicle, after self-admin	59159.07	2	2	40	0	1.00e+00	Ccny Retreg2
Time to tail flick, test, before self-admin	16410.58	2	1	20	0	1.00e+00	Ccny Retreg2
Time to tail flick, test, after self-admin	1998.64	3	2	40	0	1.00e+00	Ccny Homer1 Retreg2
Delta time to tail flick, vehicle, before/after SA	7388.28	5	2	40	0.98	4.48e-03	Ccny Homer1 Il12rb2 Lhfpl2 Retreg2
Delta time to tail flick, test, before/after SA	28423.85	2	1	20	0	1.00e+00	Ccny Retreg2
Ambulatory time before self-admin	57050.88	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Ambulatory time after self-admin	44153.3	2	2	40	0	1.00e+00	Ccny Retreg2
Total heroin consumption	370.93	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Area under the delay curve	40810.48	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 0s delay	4741.82	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 16s delay	37437.33	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	416.46	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	1298.29	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	30110.07	2	1	20	0	1.00e+00	Ccny Retreg2
Delay discount hyperbolic model param	45715.54	1	1	20	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	20	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	11821.21	2	2	40	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	16446.05	3	3	60	0	1.00e+00	Ccny Il12rb2 Retreg2
Bouts of movement, locomotor time 1	13900.93	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Total resting periods, locomotor time 1	3964.11	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Rest time, locomotor task time 1	25324.38	3	1	20	0	1.00e+00	Ccny Il12rb2 Retreg2
Distance moved, locomotor task time 1	53104.4	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Vertical activity count, locomotor time 1	109531.89	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Time >=10cm from walls, locomotor time 2	54000.88	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Bouts of movement, locomotor time 2	58112.08	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Total resting periods, locomotor time 2	63369.04	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Rest time, locomotor task time 2	41900.71	2	2	40	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	40	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	69238.05	2	2	40	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	81026.62	2	2	40	0	1.00e+00	Ccny Retreg2
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	5445.37	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion in novel chamber post-restriction	77324.49	2	1	20	0	1.00e+00	Ccny Retreg2
Progressive ratio	78975.01	2	2	40	0	1.00e+00	Ccny Retreg2
Food seeking constrained by brief footshock	3672.6	2	1	20	0	1.00e+00	Il12rb2 Retreg2
Seeking ratio, punishment vs. effort	39434.03	3	2	40	0	1.00e+00	Ccny Il12rb2 Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	20	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	14942.17	2	1	20	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	40	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	3675.36	2	2	40	0	1.00e+00	Ccny Retreg2
Co content in liver	4721.74	1	1	20	0	1.00e+00	Retreg2
Cu content in liver	84.92	2	1	20	0	1.00e+00	Homer1 Retreg2
Fe content in liver	5656.2	1	1	20	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	20	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	20	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	20	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	20	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.02
Adipose	alternative TSS	0	0	0.98
Adipose	gene expression	0	0	0.96
Adipose	isoform ratio	0	0	0.98
Adipose	intron excision ratio	0	0	1
Adipose	mRNA stability	0	0	0.97
BLA	alternative polyA	0	0	0.99
BLA	alternative TSS	0	0	1.02
BLA	gene expression	0	0	0.98
BLA	isoform ratio	0	0	1.01
BLA	intron excision ratio	0	0	0.99
BLA	mRNA stability	0	0	1
Brain	alternative polyA	0	0	0.98
Brain	alternative TSS	0	0	0.95
Brain	gene expression	0	0	0.98
Brain	isoform ratio	0	0	0.98
Brain	intron excision ratio	0	0	1
Brain	mRNA stability	0	0	0.97
Eye	alternative polyA	0	0	1.05
Eye	alternative TSS	0	0	0.9
Eye	gene expression	0	0	0.92
Eye	isoform ratio	0	0	0.84
Eye	intron excision ratio	0	0	0.96
Eye	mRNA stability	0	0	0.9
IC	alternative polyA	0	0	1
IC	alternative TSS	0	0	0.91
IC	gene expression	0	0	0.99
IC	isoform ratio	0	0	0.97
IC	intron excision ratio	0	0	1.03
IC	mRNA stability	0	0	1.03
IL	alternative polyA	0	0	1.07
IL	alternative TSS	0	0	0.99
IL	gene expression	0	0	0.95
IL	isoform ratio	0	0	1.03
IL	intron excision ratio	0	0	0.98
IL	mRNA stability	0	0	0.96
LHb	alternative polyA	0	0	0.99
LHb	alternative TSS	0	0	1.03
LHb	gene expression	0	0	0.97
LHb	isoform ratio	0	0	0.97
LHb	intron excision ratio	0	0	1.05
LHb	mRNA stability	0	0	1.05
Liver	alternative polyA	0	0	0.99
Liver	alternative TSS	0	0	0.93
Liver	gene expression	0	0	0.97
Liver	isoform ratio	0	0	0.98
Liver	intron excision ratio	0	0	0.99
Liver	mRNA stability	0	0	0.96
NAcc	alternative polyA	2	0.1	18.71
NAcc	alternative TSS	0	0	0.97
NAcc	gene expression	0	0	0.99
NAcc	isoform ratio	0	0	1.02
NAcc	intron excision ratio	0	0	1.03
NAcc	mRNA stability	1	0	0.99
OFC	alternative polyA	0	0	1.02
OFC	alternative TSS	0	0	1.02
OFC	gene expression	0	0	0.98
OFC	isoform ratio	0	0	0.98
OFC	intron excision ratio	0	0	1.02
OFC	mRNA stability	0	0	0.97
PL	alternative polyA	0	0	1.06
PL	alternative TSS	0	0	1
PL	gene expression	1	0	0.99
PL	isoform ratio	0	0	1.03
PL	intron excision ratio	0	0	1.02
PL	mRNA stability	0	0	0.95
pVTA	alternative polyA	0	0	0.99
pVTA	alternative TSS	0	0	0.94
pVTA	gene expression	1	0	1.07
pVTA	isoform ratio	0	0	0.98
pVTA	intron excision ratio	0	0	1
pVTA	mRNA stability	0	0	0.99
RMTg	alternative polyA	0	0	1.1
RMTg	alternative TSS	0	0	1.14
RMTg	gene expression	0	0	1.03
RMTg	isoform ratio	0	0	1.06
RMTg	intron excision ratio	0	0	1.06
RMTg	mRNA stability	0	0	0.97