Hub : Traits

Compulsive drug intake

Tags: Behavior · Cocaine

Project: p50_paul_meyer_2020

3 loci · 3 genes with independent associations · 3 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr5	29696024	31094456	1	1	1.36e-07	8.98e-04	6.15e-01	Rbm12b
2	chr8	41432021	42517271	1	1	2.66e-08	3.72e-01	2.47e-04	Foxred1
3	chr9	83390749	84777604	1	1	0.00e+00	2.51e-01	1.00e+00	Retreg2

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1920.83	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
BMI without tail	144009.17	1	1	33.3	0	1.00e+00	Retreg2
Body weight	3.91	1	0	0	0	1.00e+00	Retreg2
Epididymis fat weight	108443.4	1	1	33.3	0	1.00e+00	Retreg2
Glucose	2366.35	1	1	33.3	0	1.00e+00	Retreg2
Heart weight	13509	1	1	33.3	0	1.00e+00	Retreg2
Left kidney weight	70630.42	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Right kidney weight	58424.37	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Tail length	92117.69	1	1	33.3	0	1.00e+00	Retreg2
Length with tail	3070.34	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Length without tail	129313.22	1	1	33.3	0	1.00e+00	Retreg2
Liver weight, left	14514.29	1	1	33.3	0	1.00e+00	Retreg2
Liver weight, right	252.56	1	1	33.3	0	1.00e+00	Retreg2
Parametrial fat weight	309.71	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Retroperitoneal fat weight	16055.76	1	1	33.3	0	1.00e+00	Retreg2
Intraocular pressure	20038.84	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Extensor digitorum longus weight	4682.69	1	1	33.3	0	1.00e+00	Retreg2
Soleus weight	115.65	1	1	33.3	0	1.00e+00	Retreg2
Tibialis anterior weight	4881.94	1	1	33.3	0	1.00e+00	Retreg2
Tibia length	3259.43	1	1	33.3	0	1.00e+00	Retreg2
Number of licking bursts	157119.65	1	1	33.3	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	106196.53	1	1	33.3	0	1.00e+00	Retreg2
Times rat made contact with spout	305.36	1	1	33.3	0	1.00e+00	Retreg2
Mean time between licks in bursts	199507.71	1	1	33.3	0	1.00e+00	Retreg2
Mean num. licks in bursts	142600.29	1	1	33.3	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	94042.02	1	1	33.3	0	1.00e+00	Retreg2
Water consumed over 24 hours	103408.69	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	57503.51	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Patch foraging indifference point AUC	133114.6	1	1	33.3	0	1.00e+00	Retreg2
Indifference point function ln k	142006.4	1	1	33.3	0	1.00e+00	Retreg2
Indifference point function log k	142006.4	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging total patch changes 0 sec	40089.62	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Patch foraging total patch changes 12 sec	3620.02	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Patch foraging total patch changes 18 sec	117768.16	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging total patch changes 24 sec	167090.22	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging total patch changes 6 sec	32639.62	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging time to switch 0 sec	156618.53	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	161858.08	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	103280.07	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging water rate 24 sec	4691.77	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	3954.86	1	1	33.3	0	1.00e+00	Retreg2
Locomotor activity	10.62	2	0	0	0	1.00e+00	Foxred1 Retreg2
Locomotor testing distance	44728.02	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Locomotor testing rearing	38105.44	3	1	33.3	1	6.41e-04	Foxred1 Rbm12b Retreg2
Light reinforcement 1	155242.72	1	1	33.3	0	1.00e+00	Retreg2
Light reinforcement 2	53951.44	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Reaction time number correct	153465.22	1	1	33.3	0	1.00e+00	Retreg2
Reaction time mean minus median	205810.62	1	1	33.3	0	1.00e+00	Retreg2
Reaction time mean minus median AUC	208396.98	1	1	33.3	0	1.00e+00	Retreg2
Reaction time num false alarms	57075.22	1	1	33.3	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	106496.51	1	1	33.3	0	1.00e+00	Retreg2
Reaction time trials correct on left	153465.22	1	1	33.3	0	1.00e+00	Retreg2
Reaction time trials on left	149991.58	1	1	33.3	0	1.00e+00	Retreg2
Reaction time mean	94380.53	1	1	33.3	0	1.00e+00	Retreg2
Reaction time mean AUC	113341.21	1	1	33.3	0	1.00e+00	Retreg2
Median of all reaction times	31417.12	1	1	33.3	0	1.00e+00	Retreg2
Reaction time omissions	34267.91	1	1	33.3	0	1.00e+00	Retreg2
Reaction time false alarm rate	891.26	1	1	33.3	0	1.00e+00	Retreg2
Reaction time premature initiation rate	36877.02	1	1	33.3	0	1.00e+00	Retreg2
Reaction time premature initiations	138718.63	1	1	33.3	0	1.00e+00	Retreg2
Std. dev. reaction times	149487.71	1	1	33.3	0	1.00e+00	Retreg2
Reaction time trials completed	149991.58	1	1	33.3	0	1.00e+00	Retreg2
Reaction time trials AUC	151696.42	1	1	33.3	0	1.00e+00	Retreg2
Social response proportion	35302.65	1	1	33.3	0	1.00e+00	Retreg2
Social responses	5682.08	1	1	33.3	0	1.00e+00	Retreg2
Social time	22121.93	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Conditioned locomotion	6074.35	1	1	33.3	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	32908.68	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Cocaine response after cond. not corrected	32126.89	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Cocaine response before conditioning	2800.41	1	1	33.3	0	1.00e+00	Retreg2
Saline control response	12962.78	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active responses	9691.24	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	42106.18	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	15873.43	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	49418.79	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	114781.94	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. index score	47988.08	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	58476.16	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	104933.78	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	44871.67	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	5169.79	1	1	33.3	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	95747.06	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Conditioned reinforcement - inactives	51681.1	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Conditioned locomotion	20676.36	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Intermittent access intake day 1-15 change	105309.88	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Intermittent access intake escalation	104787.33	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Intermittent access intake escalation 2	54035.94	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Intermitt. access day 1 inactive lever presses	118271.66	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Intermitt. access day 15 inactive lever presses	104128.18	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Intermitt. access escalation Index	184996.65	1	1	33.3	0	1.00e+00	Retreg2
Intermittent access day 1 total infusions	38884.81	3	1	33.3	1	9.06e-04	Foxred1 Rbm12b Retreg2
Intermittent access day 15 total infusions	43841.18	3	2	66.7	0	1.00e+00	Foxred1 Rbm12b Retreg2
Intermittent access terminal intake (last 3 days)	41620.1	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Intermittent access total infusions	176.82	3	1	33.3	0.97	3.28e-02	Foxred1 Rbm12b Retreg2
Intermittent access day 1 locomotion	34823.51	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Intermittent access day 15 total locomotion	88919.72	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Intermittent access total locomotion	359.09	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Intermittent access standard deviation	100954.36	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Cocaine induced anxiety	80143.99	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Post-drug Anxiety	20460.83	1	1	33.3	0	1.00e+00	Retreg2
Baseline Anxiety	51738.82	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Lifetime Intake	1715.86	3	1	33.3	1	4.43e-03	Foxred1 Rbm12b Retreg2
Incentive Sensitization - Responses	54529.24	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Incentive Sensitization - Breakpoint	35701.55	3	1	33.3	1	2.25e-04	Foxred1 Rbm12b Retreg2
Progressive ratio test 1 active lever presses	33299.61	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Progressive ratio test 1 breakpoint	32091.79	2	2	66.7	0	1.00e+00	Rbm12b Retreg2
Progressive ratio test 1 inactive lever presses	50369.37	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Progressive ratio test 2 active lever presses	57222.6	1	1	33.3	0	1.00e+00	Retreg2
Progressive ratio test 2 breakpoint	34975.96	1	1	33.3	0	1.00e+00	Retreg2
Progressive ratio test 2 inactive lever presses	82055.01	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Total sessions with >9 infusions	7953.9	1	1	33.3	0	1.00e+00	Retreg2
Short access day 1 total inactive lever presses	57200.95	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Short access day 10 total inactive lever presses	217140.65	1	1	33.3	0	1.00e+00	Retreg2
Short access day 1 total infusions	27873.13	3	1	33.3	1	8.02e-04	Foxred1 Rbm12b Retreg2
Short access day 10 total infusions	25434.28	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Short access total infusions	11323.52	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Short access day 1 locomotion	42034.69	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Short access day 10 total locomotion	90807.64	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Short access total locomotion	34146.98	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
One hour access (0.3 mA shock)	4865.67	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
One hour access (shock baseline)	46758.97	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Number of responses in last shaping day	17101.08	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Context. condit. distance diff. score	970.59	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 1	14615.25	1	1	33.3	0	1.00e+00	Retreg2
Locomotion distance, session 1	4416.18	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 2	9358	1	1	33.3	0	1.00e+00	Retreg2
Locomotion distance, session 2	2393.66	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 3	2332.53	1	1	33.3	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	33.3	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	33.3	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	33.3	0	1.00e+00	Retreg2
Locomotion distance, session 7	3744.54	1	1	33.3	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	33.3	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 8	949.15	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Locomotion distance, session 8	673.32	1	1	33.3	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	33.3	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	8496.38	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	4120.78	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active responses	11664.93	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	19375.3	1	1	33.3	0	1.00e+00	Retreg2
Incentive salience index mean	14781.83	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	21433.81	1	1	33.3	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	33.3	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	35522.88	1	1	33.3	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	33.3	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	1687	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	1131.06	1	1	33.3	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	33.3	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	24924.95	1	1	33.3	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	280.53	1	1	33.3	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	96.8	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	145.53	1	1	33.3	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	55508.81	1	1	33.3	0	1.00e+00	Retreg2
Novelty place preference	54383.96	1	1	33.3	0	1.00e+00	Retreg2
Time in novel zone, NPP test	40844.77	1	1	33.3	0	1.00e+00	Retreg2
Total zone transitions, NPP test	8230.03	1	1	33.3	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	7114	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	4041.22	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2195.61	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	4539.35	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. index score	1769.33	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	1841.19	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	3029.77	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	2162.19	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	524.02	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	2606.99	1	1	33.3	0	1.00e+00	Retreg2
Bone: apparent density	22268.03	1	1	33.3	0	1.00e+00	Retreg2
Bone surface	25125.6	1	1	33.3	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	33.3	0	1.00e+00	Retreg2
Bone: connectivity density	7098.55	1	1	33.3	0	1.00e+00	Retreg2
Bone: cortical apparent density	45266.32	1	1	33.3	0	1.00e+00	Retreg2
Bone: cortical area	18930.98	1	1	33.3	0	1.00e+00	Retreg2
Bone: cortical porosity	1837.29	1	1	33.3	0	1.00e+00	Retreg2
Bone: cortical porosity	4807.78	1	1	33.3	0	1.00e+00	Retreg2
Bone: cortical thickness	1627.26	1	1	33.3	0	1.00e+00	Retreg2
Bone: cortical thickness	12190.6	1	1	33.3	0	1.00e+00	Retreg2
Bone: cortical tissue density	48453.42	1	1	33.3	0	1.00e+00	Retreg2
Bone: elastic displacement	29626.25	1	1	33.3	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	33.3	0	1.00e+00	Retreg2
Bone: endosteal estimation	17630.92	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Bone: endosteal perimeter	44697.39	1	1	33.3	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	33.3	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	33.3	0	1.00e+00	Retreg2
Bone: marrow area	18536.11	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Bone: maximum diameter	24401.62	1	1	33.3	0	1.00e+00	Retreg2
Bone: maximum force	34553.99	1	1	33.3	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	33.3	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	33.3	0	1.00e+00	Retreg2
Bone: periosteal estimation	19097.19	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Bone: periosteal perimeter	43183.28	1	1	33.3	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	33.3	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	33.3	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	33.3	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	33.3	0	1.00e+00	Retreg2
Bone: trabecular spacing	31287.85	1	1	33.3	0	1.00e+00	Retreg2
Bone: trabecular thickness	33264.33	1	1	33.3	0	1.00e+00	Retreg2
Bone: trabecular tissue density	53620.06	1	1	33.3	0	1.00e+00	Retreg2
Breakpoint value in progressive ratio session	112428.06	1	1	33.3	0	1.00e+00	Retreg2
Distance traveled before self-admin	67011.51	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Distance traveled after self-admin	50416.54	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Delta time in closed arm before/after self-admin	649.88	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Delta time in open arm before/after self-admin	54811.83	1	1	33.3	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	108490.77	1	1	33.3	0	1.00e+00	Retreg2
Extinction: sum of active levers before priming	30534.8	3	2	66.7	0	1.00e+00	Foxred1 Rbm12b Retreg2
Active lever presses in extinction session 6	786.34	3	1	33.3	0.99	8.34e-03	Foxred1 Rbm12b Retreg2
Delta distance traveled before/after self-admin	6221	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Delta ambulatory time before/after self-admin	48023.33	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Time in closed arm before self-admin	44122	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Time in closed arm after self-admin	19471.75	1	1	33.3	0	1.00e+00	Retreg2
Time in open arm before self-admin	17297	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Time in open arm after self-admin	950.9	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Sum of active levers in priming session hrs 5-6	3877.89	1	1	33.3	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	25672.17	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Time to tail flick, vehicle, after self-admin	59145.9	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Time to tail flick, test, before self-admin	10941.72	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Time to tail flick, test, after self-admin	2918.79	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Delta time to tail flick, vehicle, before/after SA	36533.83	1	1	33.3	0	1.00e+00	Retreg2
Delta time to tail flick, test, before/after SA	56832.34	1	1	33.3	0	1.00e+00	Retreg2
Ambulatory time before self-admin	85546.65	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Ambulatory time after self-admin	88230.17	1	1	33.3	0	1.00e+00	Retreg2
Total heroin consumption	493.2	2	2	66.7	0	1.00e+00	Foxred1 Retreg2
Area under the delay curve	81605.23	1	1	33.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	9477.47	1	1	33.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	74803.61	1	1	33.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	825.84	1	1	33.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	49994.3	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Delay disc. indifference point, 4s delay	2525.7	1	1	33.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	33.3	0	1.00e+00	Retreg2
Delay discount exponential model param	60214.95	1	1	33.3	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	45715.54	1	1	33.3	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	150160.89	1	1	33.3	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	23481.3	1	1	33.3	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 1	49255.61	1	1	33.3	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 1	41590.88	1	1	33.3	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	11802.64	1	1	33.3	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	75951.88	1	1	33.3	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	159283.67	1	1	33.3	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	219061.96	1	1	33.3	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	161986.9	1	1	33.3	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	87150.72	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Total resting periods, locomotor time 2	95040.97	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Rest time, locomotor task time 2	83778.18	1	1	33.3	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	34268.85	1	1	33.3	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	138414.05	1	1	33.3	0	1.00e+00	Retreg2
Weight adjusted by age	161973.18	1	1	33.3	0	1.00e+00	Retreg2
Seeking ratio, delayed vs. immediate footshock	49395.56	1	1	33.3	0	1.00e+00	Retreg2
Locomotion in novel chamber	8157.38	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Locomotion in novel chamber post-restriction	154642.04	1	1	33.3	0	1.00e+00	Retreg2
Progressive ratio	157894.89	1	1	33.3	0	1.00e+00	Retreg2
Food seeking constrained by brief footshock	7338.76	1	1	33.3	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	59142.58	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Run reversals in cocaine runway, females	18593.97	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Run reversals in cocaine runway, males	14937.45	2	1	33.3	0	1.00e+00	Foxred1 Retreg2
Latency to leave start box in cocaine runway	29290.2	2	1	33.3	0	1.00e+00	Rbm12b Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	33.3	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	2385.69	3	1	33.3	0	1.00e+00	Foxred1 Rbm12b Retreg2
Co content in liver	4721.74	1	1	33.3	0	1.00e+00	Retreg2
Cu content in liver	162.43	1	1	33.3	0	1.00e+00	Retreg2
Fe content in liver	5656.2	1	1	33.3	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	33.3	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	33.3	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	33.3	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	33.3	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	33.3	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	33.3	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.14
Adipose	alternative TSS	0	0	1.16
Adipose	gene expression	0	0	1.06
Adipose	isoform ratio	0	0	1.09
Adipose	intron excision ratio	0	0	1.26
Adipose	mRNA stability	0	0	1.04
BLA	alternative polyA	0	0	1.04
BLA	alternative TSS	0	0	1.05
BLA	gene expression	0	0	1.06
BLA	isoform ratio	0	0	1.1
BLA	intron excision ratio	0	0	1.3
BLA	mRNA stability	0	0	1.01
Brain	alternative polyA	0	0	1.05
Brain	alternative TSS	0	0	1.02
Brain	gene expression	0	0	1.02
Brain	isoform ratio	0	0	1.1
Brain	intron excision ratio	0	0	1.24
Brain	mRNA stability	0	0	1.05
Eye	alternative polyA	0	0	1.02
Eye	alternative TSS	0	0	1.19
Eye	gene expression	0	0	1.09
Eye	isoform ratio	0	0	1.2
Eye	intron excision ratio	0	0	1.39
Eye	mRNA stability	0	0	1.08
IC	alternative polyA	0	0	1.12
IC	alternative TSS	1	0.1	1.07
IC	gene expression	0	0	1.08
IC	isoform ratio	0	0	1.13
IC	intron excision ratio	0	0	1.34
IC	mRNA stability	0	0	1.07
IL	alternative polyA	0	0	1.2
IL	alternative TSS	0	0	1.16
IL	gene expression	0	0	1.07
IL	isoform ratio	0	0	1.12
IL	intron excision ratio	0	0	1.27
IL	mRNA stability	0	0	1.05
LHb	alternative polyA	0	0	1.15
LHb	alternative TSS	0	0	1.29
LHb	gene expression	0	0	1.09
LHb	isoform ratio	0	0	1.2
LHb	intron excision ratio	0	0	1.44
LHb	mRNA stability	0	0	1.01
Liver	alternative polyA	0	0	1.17
Liver	alternative TSS	0	0	1.06
Liver	gene expression	0	0	1.05
Liver	isoform ratio	0	0	1.09
Liver	intron excision ratio	0	0	1.2
Liver	mRNA stability	0	0	1.02
NAcc	alternative polyA	1	0	28.12
NAcc	alternative TSS	1	0	1.03
NAcc	gene expression	0	0	1.03
NAcc	isoform ratio	0	0	1.07
NAcc	intron excision ratio	1	0	1.2
NAcc	mRNA stability	0	0	1.01
OFC	alternative polyA	0	0	1.08
OFC	alternative TSS	0	0	1.09
OFC	gene expression	0	0	1.09
OFC	isoform ratio	0	0	1.12
OFC	intron excision ratio	0	0	1.41
OFC	mRNA stability	0	0	1.01
PL	alternative polyA	0	0	1.12
PL	alternative TSS	0	0	1.07
PL	gene expression	0	0	1.04
PL	isoform ratio	0	0	1.11
PL	intron excision ratio	0	0	1.25
PL	mRNA stability	0	0	1.04
pVTA	alternative polyA	0	0	1.14
pVTA	alternative TSS	0	0	1.09
pVTA	gene expression	0	0	1.08
pVTA	isoform ratio	0	0	1.12
pVTA	intron excision ratio	0	0	1.23
pVTA	mRNA stability	0	0	1.08
RMTg	alternative polyA	0	0	1.11
RMTg	alternative TSS	0	0	1.14
RMTg	gene expression	0	0	1.15
RMTg	isoform ratio	0	0	1.25
RMTg	intron excision ratio	0	0	1.5
RMTg	mRNA stability	0	0	1.06