Median of all reaction times for males and females [cs]
Project: p50_david_dietz
3 significantly associated models · 3 unique genes
| # | chr | p0 | p1 | # assoc genes | # joint models | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 7 | 36928280 | 39249627 | 2 | 1 | 1.3e-07 | 1.6e-08 | 1 | 100 | Nts |
| 2 | 7 | 40107444 | 41504493 | 1 | 1 | 1.1e-08 | 6.0e-09 | 1 | 100 | Tmtc2 |
p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.
| Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
|---|---|---|---|---|---|---|---|
| body_g | 1.7 | 2 | 0 | 0 | 0 | 1 | Nts Slc6a15 |
| reaction_time_corr | 7.1 | 3 | 0 | 0 | 0 | 1 | Nts Tmtc2 Slc6a15 |
| reaction_time_leftcorr | 7.1 | 3 | 0 | 0 | 0 | 1 | Nts Tmtc2 Slc6a15 |
| tautz: manual_spc7 | 4.2 | 1 | 0 | 0 | 0 | 1 | Slc6a15 |
| tautz: manual_mpc4 | 10.7 | 2 | 0 | 0 | 0 | 1 | Nts Slc6a15 |
| tautz: manual_mpc5 | 7.9 | 3 | 0 | 0 | 0 | 1 | Nts Tmtc2 Slc6a15 |
| tautz: manual_spc10 | 4.7 | 2 | 0 | 0 | 0 | 1 | Tmtc2 Slc6a15 |
| tautz: manual_mpc2 | 6.1 | 2 | 0 | 0 | 0 | 1 | Nts Slc6a15 |
| tautz: manual_spc16 | 5.7 | 2 | 0 | 0 | 0 | 1 | Nts Slc6a15 |
| tautz: manual_spc5 | 5.2 | 1 | 0 | 0 | 0 | 1 | Tmtc2 |
| tautz: manual_mpc11 | 4.7 | 1 | 0 | 0 | 0 | 1 | Slc6a15 |
chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.
| tissue | modality | # hits | % hits/tests | avg chisq |
|---|---|---|---|---|
| Adipose | alternative polyA | 0 | 0.000 | 1.31 |
| Adipose | alternative TSS | 0 | 0.000 | 1.25 |
| Adipose | gene expression | 0 | 0.000 | 1.34 |
| Adipose | isoform ratio | 0 | 0.000 | 1.37 |
| Adipose | intron excision ratio | 0 | 0.000 | 1.41 |
| Adipose | mRNA stability | 0 | 0.000 | 1.33 |
| BLA | alternative polyA | 0 | 0.000 | 1.31 |
| BLA | alternative TSS | 0 | 0.000 | 1.18 |
| BLA | gene expression | 0 | 0.000 | 1.35 |
| BLA | isoform ratio | 0 | 0.000 | 1.39 |
| BLA | intron excision ratio | 0 | 0.000 | 1.38 |
| BLA | mRNA stability | 0 | 0.000 | 1.42 |
| Brain | alternative polyA | 0 | 0.000 | 1.36 |
| Brain | alternative TSS | 0 | 0.000 | 1.33 |
| Brain | gene expression | 0 | 0.000 | 1.37 |
| Brain | isoform ratio | 0 | 0.000 | 1.37 |
| Brain | intron excision ratio | 0 | 0.000 | 1.44 |
| Brain | mRNA stability | 0 | 0.000 | 1.40 |
| Eye | alternative polyA | 0 | 0.000 | 1.40 |
| Eye | alternative TSS | 0 | 0.000 | 0.85 |
| Eye | gene expression | 0 | 0.000 | 1.42 |
| Eye | isoform ratio | 0 | 0.000 | 1.28 |
| Eye | intron excision ratio | 0 | 0.000 | 1.43 |
| Eye | mRNA stability | 0 | 0.000 | 1.25 |
| IL | alternative polyA | 0 | 0.000 | 1.31 |
| IL | alternative TSS | 0 | 0.000 | 1.29 |
| IL | gene expression | 1 | 0.027 | 1.31 |
| IL | isoform ratio | 0 | 0.000 | 1.37 |
| IL | intron excision ratio | 0 | 0.000 | 1.35 |
| IL | mRNA stability | 0 | 0.000 | 1.47 |
| LHb | alternative polyA | 0 | 0.000 | 1.21 |
| LHb | alternative TSS | 0 | 0.000 | 1.42 |
| LHb | gene expression | 1 | 0.031 | 1.31 |
| LHb | isoform ratio | 0 | 0.000 | 1.52 |
| LHb | intron excision ratio | 0 | 0.000 | 1.44 |
| LHb | mRNA stability | 0 | 0.000 | 1.45 |
| Liver | alternative polyA | 0 | 0.000 | 1.32 |
| Liver | alternative TSS | 0 | 0.000 | 1.28 |
| Liver | gene expression | 0 | 0.000 | 1.33 |
| Liver | isoform ratio | 0 | 0.000 | 1.35 |
| Liver | intron excision ratio | 0 | 0.000 | 1.33 |
| Liver | mRNA stability | 0 | 0.000 | 1.32 |
| NAcc | alternative polyA | 0 | 0.000 | 1.27 |
| NAcc | alternative TSS | 0 | 0.000 | 1.30 |
| NAcc | gene expression | 0 | 0.000 | 1.32 |
| NAcc | isoform ratio | 0 | 0.000 | 1.40 |
| NAcc | intron excision ratio | 0 | 0.000 | 1.41 |
| NAcc | mRNA stability | 0 | 0.000 | 1.44 |
| NAcc2 | alternative polyA | 0 | 0.000 | 1.41 |
| NAcc2 | alternative TSS | 0 | 0.000 | 1.28 |
| NAcc2 | gene expression | 1 | 0.019 | 1.35 |
| NAcc2 | isoform ratio | 0 | 0.000 | 1.42 |
| NAcc2 | intron excision ratio | 0 | 0.000 | 1.44 |
| NAcc2 | mRNA stability | 0 | 0.000 | 1.39 |
| OFC | alternative polyA | 0 | 0.000 | 1.12 |
| OFC | alternative TSS | 0 | 0.000 | 1.44 |
| OFC | gene expression | 0 | 0.000 | 1.32 |
| OFC | isoform ratio | 0 | 0.000 | 1.48 |
| OFC | intron excision ratio | 0 | 0.000 | 1.41 |
| OFC | mRNA stability | 0 | 0.000 | 1.42 |
| PL | alternative polyA | 0 | 0.000 | 1.41 |
| PL | alternative TSS | 0 | 0.000 | 1.51 |
| PL | gene expression | 0 | 0.000 | 1.34 |
| PL | isoform ratio | 0 | 0.000 | 1.35 |
| PL | intron excision ratio | 0 | 0.000 | 1.28 |
| PL | mRNA stability | 0 | 0.000 | 1.40 |
| PL2 | alternative polyA | 0 | 0.000 | 1.26 |
| PL2 | alternative TSS | 0 | 0.000 | 1.19 |
| PL2 | gene expression | 0 | 0.000 | 1.34 |
| PL2 | isoform ratio | 0 | 0.000 | 1.41 |
| PL2 | intron excision ratio | 0 | 0.000 | 1.44 |
| PL2 | mRNA stability | 0 | 0.000 | 1.37 |
avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.