Hub : Genes

Rnf121

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Rnf121 0.04 0.03 2.2e-03 0.01 0.01 0.02 0.02 7.2e-03 8.4e-03 4.5e-03 6.5e-03
2 Brain gene expression Rnf121 0.06 0.05 7.1e-04 0.03 0.03 0.02 0.02 1.7e-03 1.9e-03 4.5e-03 3.4e-03
3 PL gene expression Rnf121 0.03 0.03 4.2e-03 0.02 0.01 -0 0.01 1.9e-03 2.8e-02 5.6e-01 1.2e-02
4 pVTA gene expression Rnf121 0.04 0.03 7.1e-03 0.03 0.03 0.02 0.02 2.9e-03 3.2e-03 1.0e-02 1.6e-02
5 RMTg mRNA stability Rnf121 0.16 0.11 3.2e-03 0.03 0.04 0.03 0.03 6.8e-02 3.1e-02 7.3e-02 5.5e-02
6 Adipose mRNA stability Rnf121 0.06 0.04 2.6e-05 0.03 0.04 0.03 0.03 5.4e-04 5.6e-05 1.8e-04 1.7e-04
7 Adipose gene expression Rnf121 0.04 0.03 5.7e-04 0.01 0.02 0.02 0.01 1.6e-02 2.1e-03 3.4e-03 7.5e-03
8 NAcc gene expression Rnf121 0.03 0.02 2.8e-04 0.01 0.02 0.02 0.02 3.5e-03 5.3e-04 1.3e-04 1.5e-03
9 Brain mRNA stability Rnf121 0.12 0.07 2.4e-08 0.08 0.09 0.08 0.08 3.0e-08 1.2e-08 4.0e-08 4.3e-08
10 PL mRNA stability Rnf121 0.06 0.04 4.0e-06 0.05 0.06 0.06 0.05 1.5e-06 1.2e-06 7.5e-07 3.7e-06
11 OFC mRNA stability Rnf121 0.15 0.11 5.2e-03 0.05 0.11 0.05 0.09 3.0e-02 1.5e-03 2.6e-02 4.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.30.5-0.7-0.6-0.6-0.60.50.60.5-0.5-0.40.2-0.0
Area under the delay curve0.30.41.2-0.8-0.6-0.6-0.61.10.40.1-0.20.3-0.60.9
BMI with tail0.62.26.1-0.3-0.4-0.4-0.3-1.11.21.7-1.5-2.22.2-2.5
BMI without tail0.42.05.61.61.51.51.4-2.4-0.7-0.10.2-0.81.6-1.9
Body weight0.20.91.71.31.11.11.3-1.1-1.1-0.91.00.6-0.2-0.2
Weight adjusted by age0.20.61.51.20.90.90.9-0.9-1.0-0.80.50.6-0.20.0
Bone surface0.50.91.41.01.01.01.0-0.5-1.2-1.21.11.1-0.70.6
Bone volume0.20.40.70.60.60.60.5-0.1-0.8-0.80.80.8-0.60.6
Breakpoint value in progressive ratio session0.40.81.5-0.8-0.5-0.5-1.10.71.21.2-1.0-1.00.8-0.4
Number of licking bursts1.23.56.0-2.4-2.4-2.4-2.42.22.01.7-1.8-1.0-0.10.4
Context. condit. distance diff. score2.53.15.92.32.32.32.2-2.4-1.7-1.21.10.40.9-1.1
Locomotion velocity, session 11.61.83.3-1.0-0.8-0.8-0.9-0.11.41.6-1.7-1.81.8-1.5
Locomotion distance, session 10.70.92.50.60.70.70.6-1.4-0.00.4-0.3-1.01.5-1.6
Locomotion velocity, session 20.60.72.30.00.20.2-0.0-0.90.50.8-0.7-1.21.5-1.4
Locomotion distance, session 20.60.92.80.40.40.40.3-1.30.30.7-0.6-1.21.6-1.7
Locomotion velocity, session 30.40.51.10.91.01.00.6-0.9-0.7-0.60.50.20.2-0.3
Locomotion distance, session 30.50.61.31.01.01.00.7-1.1-0.6-0.30.3-0.10.6-0.7
Stereotopy head waving bouts, day 30.30.41.2-0.1-0.2-0.20.00.7-0.3-0.50.60.8-1.11.0
Stereotopy head waving duration, day 30.20.20.60.60.40.40.8-0.7-0.4-0.30.60.00.0-0.4
Locomotion velocity, session 70.70.72.0-0.4-0.3-0.3-0.4-0.30.81.0-1.1-1.21.4-1.1
Locomotion distance, session 70.20.20.4-0.6-0.5-0.5-0.60.60.50.4-0.6-0.20.30.1
Stereotopy head waving bouts, day 72.63.15.22.22.22.22.3-2.1-1.8-1.41.60.70.3-0.6
Stereotopy head waving duration, day 72.43.05.32.22.22.22.3-2.3-1.8-1.31.50.60.4-0.8
Locomotion velocity, session 81.11.42.71.61.61.61.2-1.4-1.3-1.00.70.50.5-0.3
Locomotion distance, session 82.03.07.02.22.22.21.9-2.7-1.4-0.70.7-0.21.4-1.6
Degree of sensitization distance0.40.41.3-0.4-0.3-0.3-0.30.9-0.1-0.40.20.8-0.91.1
Degree of sensitization stereotypy4.85.38.93.03.03.02.9-2.8-2.4-1.92.01.00.4-0.7
Conditioned locomotion0.30.41.1-0.5-0.4-0.4-0.51.00.1-0.20.00.6-0.71.0
Cocaine response after cond. corrected0.81.22.1-1.4-1.4-1.4-1.21.31.21.0-1.0-0.5-0.10.3
Cocaine response after cond. not corrected0.60.91.3-1.0-1.0-1.0-0.90.51.11.1-1.1-1.00.6-0.6
Cocaine response before conditioning1.11.33.61.21.21.21.0-1.9-0.40.10.0-0.81.5-1.7
Saline control response2.63.55.22.02.02.01.9-1.0-2.3-2.32.22.1-1.41.2
Bone: connectivity density0.61.02.0-0.6-0.5-0.5-0.6-0.31.01.2-1.2-1.41.4-1.3
Bone: cortical apparent density0.81.32.6-1.5-1.5-1.5-1.41.61.10.7-0.6-0.2-0.60.7
Bone: cortical area0.10.20.20.40.50.50.3-0.2-0.5-0.50.40.4-0.20.3
Bone: cortical porosity0.10.10.30.00.10.1-0.10.3-0.2-0.30.40.4-0.50.5
Bone: cortical porosity0.10.20.30.30.30.30.20.0-0.4-0.50.50.6-0.50.5
Bone: cortical thickness0.71.21.8-1.1-1.0-1.0-1.00.31.31.4-1.3-1.31.1-0.9
Bone: cortical thickness0.00.00.10.10.20.20.2-0.1-0.2-0.20.30.1-0.10.1
Bone: cortical tissue density0.81.32.7-1.6-1.5-1.5-1.41.61.10.8-0.7-0.2-0.60.7
Condit. Reinf. active minus inactive responses1.41.62.81.00.90.91.0-0.0-1.4-1.61.51.7-1.51.3
Condit. Reinf. active-inactive response ratio2.62.85.11.31.21.21.30.0-1.8-2.11.92.3-2.01.9
Condit. Reinf. active responses0.60.82.00.20.20.20.30.6-0.7-1.01.01.3-1.41.4
Condit. Reinf. inactive responses0.30.40.7-0.8-0.8-0.8-0.80.60.80.7-0.6-0.50.1-0.1
Incentive salience index mean0.71.02.00.60.50.50.60.2-1.0-1.21.21.3-1.41.2
Condit. Reinf. lever presses0.00.00.00.0-0.1-0.10.10.0-0.0-0.00.20.0-0.20.0
Condit. Reinf. active minus inactive responses6.19.414.73.83.73.73.5-2.8-3.6-3.23.32.5-1.00.5
Condit. Reinf. active-inactive response ratio0.81.32.31.51.51.51.3-1.4-1.2-1.01.00.60.1-0.3
Condit. Reinf. active responses9.213.219.84.54.34.34.1-3.0-4.3-4.03.93.1-1.40.9
Condit. Reinf. inactive responses4.56.69.43.02.92.92.8-1.7-3.1-3.02.92.5-1.51.2
Condit. Reinf. lever presses11.717.028.65.35.25.25.0-4.5-4.6-3.94.02.6-0.4-0.4
Condit. Reinf. lever reinforcers received9.913.921.14.64.44.44.2-3.2-4.4-4.04.03.1-1.40.8
Conditioned reinforcement - actives0.00.10.9-0.20.40.40.2-0.4-0.10.0-0.3-0.20.9-0.4
Conditioned reinforcement - inactives0.41.02.1-1.2-1.3-1.3-1.11.50.50.1-0.20.4-1.11.2
Conditioned locomotion0.50.83.10.10.50.50.9-1.3-0.10.3-0.1-0.81.8-1.4
Patch foraging indifference point 0 sec0.92.44.42.01.91.92.1-1.9-1.7-1.31.50.70.1-0.5
Patch foraging indifference point AUC0.20.50.90.80.70.70.9-0.4-0.8-0.81.00.7-0.50.4
Delay disc. indifference point, 0s delay0.70.81.41.11.11.11.2-0.9-1.0-0.90.90.6-0.20.0
Delay disc. indifference point, 16s delay0.50.72.3-0.6-0.5-0.5-0.51.40.1-0.40.40.9-1.31.5
Delay disc. indifference point, 2s delay0.60.71.20.60.70.70.8-0.1-1.0-1.11.01.1-0.80.9
Delay disc. indifference point, 24s delay0.71.23.6-1.3-1.1-1.1-1.41.90.90.5-0.60.2-0.81.2
Delay disc. indifference point, 4s delay1.31.42.01.21.31.31.2-0.4-1.3-1.41.41.4-0.90.9
Delay disc. indifference point, 8s delay0.30.41.2-1.1-0.9-0.9-0.70.80.60.4-0.4-0.1-0.10.4
Indifference point function ln k0.00.10.30.30.30.30.2-0.6-0.10.1-0.1-0.30.4-0.6
Indifference point function log k0.00.10.30.30.30.30.2-0.6-0.10.1-0.1-0.30.4-0.6
Patch foraging total patch changes 0 sec0.72.13.81.91.71.72.0-1.9-1.5-1.11.30.50.3-0.7
Patch foraging total patch changes 12 sec1.01.32.21.31.21.21.5-0.8-1.3-1.31.31.1-0.50.5
Patch foraging total patch changes 18 sec0.61.42.41.41.41.41.5-1.2-1.3-1.11.20.8-0.2-0.0
Patch foraging total patch changes 24 sec0.41.52.61.51.31.31.6-0.9-1.5-1.41.41.2-0.60.4
Patch foraging total patch changes 6 sec0.61.02.41.31.01.01.6-1.2-1.0-0.81.00.4-0.0-0.4
Patch foraging time to switch 0 sec1.14.27.4-2.7-2.5-2.5-2.72.52.21.8-1.9-1.0-0.10.5
Patch foraging water rate 0 sec0.93.25.72.42.22.22.4-2.1-2.0-1.61.61.00.1-0.3
Patch foraging water rate 12 sec0.62.26.11.51.41.41.3-2.5-0.50.2-0.2-1.12.0-2.3
Patch foraging water rate 18 sec1.22.65.72.22.12.11.9-2.4-1.5-1.01.00.20.8-1.2
Patch foraging water rate 24 sec0.40.62.10.40.40.40.3-1.20.20.5-0.4-1.01.3-1.5
Patch foraging water rate 6 sec0.60.92.40.80.80.80.8-1.5-0.10.3-0.3-0.91.4-1.5
Seeking ratio, delayed vs. immediate footshock1.62.23.4-1.8-1.7-1.7-1.71.21.81.7-1.5-1.40.7-0.5
Distance traveled before self-admin0.30.71.4-0.3-0.1-0.1-0.70.00.91.1-1.1-1.11.2-0.9
Distance traveled after self-admin0.81.43.4-0.4-0.2-0.2-0.4-0.71.01.4-1.3-1.71.9-1.8
Extensor digitorum longus weight0.10.20.4-0.6-0.5-0.5-0.60.40.60.5-0.5-0.40.3-0.1
Bone: elastic displacement2.02.63.7-1.7-1.7-1.7-1.60.81.91.9-1.9-1.71.2-1.0
Bone: elastic work3.74.87.3-2.2-2.1-2.1-2.10.82.62.7-2.6-2.62.0-1.7
Bone: endosteal estimation1.33.25.01.81.81.81.6-0.7-2.1-2.22.02.1-1.41.4
Bone: endosteal perimeter1.53.85.52.22.22.22.0-1.1-2.3-2.32.12.0-1.21.1
Epididymis fat weight0.20.81.2-1.1-1.0-1.0-1.00.71.11.0-1.0-0.80.4-0.3
Delta time in closed arm before/after self-admin0.70.71.7-1.1-1.0-1.0-1.01.30.70.4-0.20.0-0.50.7
Delta time in open arm before/after self-admin2.32.74.51.81.41.42.1-1.3-2.1-2.01.71.7-1.30.7
Diff in mean of infusions in LGA sessions1.22.16.8-1.4-1.3-1.3-1.52.60.80.20.10.8-1.72.1
Delay discount exponential model param0.30.41.10.80.60.60.7-1.0-0.5-0.20.3-0.10.4-0.7
Extinction: sum of active levers before priming0.10.10.20.20.40.4-0.30.0-0.3-0.40.50.4-0.40.3
Active lever presses in extinction session 60.70.72.00.80.60.60.8-1.4-0.10.30.3-0.71.1-1.4
Bone: final force0.50.82.2-0.7-0.6-0.6-0.71.40.1-0.30.20.9-1.21.5
Bone: final moment0.30.51.8-0.5-0.4-0.4-0.51.1-0.1-0.40.30.8-1.11.3
Food consumed during 24 hour testing period1.12.24.51.91.91.91.9-2.1-1.4-1.01.10.30.6-1.0
Glucose0.20.31.1-0.1-0.0-0.0-0.0-0.50.40.6-0.5-0.81.0-0.9
Heart weight0.91.52.51.61.31.31.5-1.0-1.5-1.41.31.2-0.80.4
Delay discount hyperbolic model param0.20.30.90.70.50.50.5-1.0-0.3-0.00.1-0.30.5-0.8
Intermittent access intake day 1-15 change0.41.98.4-0.60.00.00.4-1.50.51.0-1.1-1.62.9-2.2
Intermittent access intake escalation0.31.77.7-0.20.50.50.7-1.70.10.7-0.8-1.32.8-2.1
Intermittent access intake escalation 20.30.52.8-0.7-0.0-0.0-0.0-0.80.20.4-0.7-0.71.7-1.0
Intermitt. access day 1 inactive lever presses0.22.55.0-2.2-2.2-2.2-1.82.21.30.8-0.6-0.0-1.01.1
Intermitt. access day 15 inactive lever presses0.10.72.3-1.5-1.3-1.3-0.80.60.50.4-0.7-0.20.20.2
Intermitt. access escalation Index0.00.10.1-0.00.10.10.30.1-0.2-0.30.20.3-0.30.3
Intermittent access day 1 total infusions0.41.12.11.21.51.51.0-0.8-1.2-1.20.90.9-0.20.4
Intermittent access day 15 total infusions0.20.61.40.41.01.00.9-1.2-0.7-0.40.00.11.2-0.6
Intermittent access terminal intake (last 3 days)0.40.71.30.41.11.11.0-1.1-0.9-0.70.40.41.0-0.3
Intermittent access total infusions0.60.71.30.41.11.11.0-1.1-0.9-0.80.70.40.9-0.3
Intermittent access day 1 locomotion0.10.20.5-0.3-0.1-0.10.30.3-0.4-0.60.40.7-0.50.7
Intermittent access day 15 total locomotion0.20.63.0-0.30.20.20.2-0.70.30.6-0.7-0.91.7-1.1
Intermittent access total locomotion0.20.30.7-0.00.60.60.8-0.7-0.6-0.40.40.20.9-0.2
Intermittent access standard deviation0.10.31.1-0.4-0.2-0.20.1-0.50.30.6-0.4-0.71.0-0.9
Left kidney weight0.10.51.31.00.70.71.2-0.9-0.7-0.50.70.2-0.1-0.4
Right kidney weight0.21.42.41.51.11.11.5-0.9-1.4-1.31.41.1-0.90.4
Cocaine induced anxiety1.02.85.8-2.3-2.2-2.2-1.92.41.51.0-0.6-0.2-1.11.2
Post-drug Anxiety1.61.84.0-1.3-1.5-1.5-1.02.00.4-0.20.60.9-1.81.9
Baseline Anxiety1.52.54.01.81.31.32.0-1.0-2.0-2.01.91.7-1.10.9
Tail length2.010.816.53.33.13.13.1-1.2-3.9-4.14.03.9-3.02.6
Length with tail2.08.813.72.92.72.72.8-0.9-3.5-3.73.63.6-2.82.5
Length without tail0.10.30.70.30.20.20.30.2-0.5-0.60.70.8-0.80.7
Times rat made contact with spout0.20.20.5-0.5-0.4-0.4-0.40.70.2-0.00.00.3-0.60.6
Lifetime Intake0.91.12.00.81.41.41.3-1.4-1.1-0.90.80.41.0-0.4
Liver weight, left0.30.51.3-0.5-0.4-0.4-0.61.00.0-0.30.10.7-1.01.2
Liver weight, right0.40.72.3-0.3-0.3-0.3-0.41.1-0.2-0.60.41.1-1.21.5
Locomotor activity0.40.61.31.00.90.91.1-1.2-0.7-0.40.50.00.5-0.6
Locomotor testing distance0.82.03.41.91.81.81.8-1.7-1.5-1.21.20.60.3-0.4
Locomotor testing rearing0.31.21.81.31.31.31.2-0.8-1.3-1.21.21.0-0.30.4
Locomotion in novel chamber1.01.42.2-0.9-1.0-1.0-1.20.21.41.5-1.4-1.51.1-1.2
Locomotion in novel chamber post-restriction0.10.41.40.80.80.80.7-1.2-0.5-0.2-0.0-0.20.5-0.8
Fecal boli incidents, locomotor time 10.51.22.5-1.4-1.1-1.1-1.51.61.31.0-1.2-0.50.10.5
Change in fecal boli incidents, locomotor task0.20.20.80.30.20.20.9-0.5-0.6-0.50.90.3-0.2-0.0
Time >=10cm from walls, locomotor time 10.60.71.60.70.60.61.1-0.6-1.0-1.01.30.9-0.70.4
Bouts of movement, locomotor time 10.50.61.70.3-0.0-0.00.40.5-0.7-0.90.71.2-1.31.2
Total resting periods, locomotor time 10.20.20.6-0.3-0.6-0.6-0.10.6-0.1-0.20.10.5-0.80.7
Rest time, locomotor task time 10.10.20.5-0.6-0.7-0.70.10.3-0.2-0.30.20.4-0.30.6
Distance moved, locomotor task time 10.10.10.40.50.60.6-0.1-0.20.20.3-0.2-0.30.4-0.4
Vertical activity count, locomotor time 10.00.10.20.30.40.4-0.00.2-0.0-0.10.20.2-0.30.3
Time >=10cm from walls, locomotor time 21.33.76.31.61.31.32.2-1.0-2.4-2.52.52.3-1.81.4
Bouts of movement, locomotor time 20.51.84.70.30.30.30.40.8-1.2-1.71.42.0-1.92.2
Total resting periods, locomotor time 20.31.13.8-0.10.00.0-0.11.1-0.7-1.10.91.6-1.61.9
Rest time, locomotor task time 21.22.13.4-1.8-1.5-1.5-1.91.51.71.5-1.6-1.10.6-0.1
Distance moved, locomotor task time 21.52.03.81.61.51.51.9-1.5-1.7-1.51.61.0-0.40.0
Vertical activity count, locomotor time 20.30.71.40.50.60.60.90.0-0.9-1.11.21.1-0.81.0
Light reinforcement 10.83.75.5-2.0-2.0-2.0-2.01.02.32.3-2.3-2.01.4-1.1
Light reinforcement 21.33.07.4-0.5-0.4-0.4-0.6-1.11.42.0-1.9-2.52.7-2.7
Bone: marrow area1.12.74.31.61.61.61.4-0.5-2.0-2.11.92.0-1.41.4
Bone: maximum diameter1.63.24.62.12.12.11.9-1.3-2.1-2.01.91.7-0.80.7
Bone: maximum force0.10.30.7-0.5-0.3-0.3-0.60.90.1-0.1-0.00.4-0.50.9
Bone: maximum moment0.10.10.4-0.2-0.1-0.1-0.40.50.0-0.2-0.00.3-0.30.6
Mean time between licks in bursts1.48.613.13.02.92.92.8-1.2-3.5-3.63.63.3-2.52.1
Mean num. licks in bursts1.23.15.12.32.22.22.2-2.0-2.0-1.61.81.0-0.1-0.2
Cd content in liver0.30.31.0-0.3-0.2-0.2-0.40.8-0.1-0.40.10.7-0.71.0
Co content in liver2.32.74.11.61.51.51.6-0.5-1.9-2.02.02.0-1.41.3
Cu content in liver1.21.52.61.00.90.91.0-0.1-1.4-1.51.51.6-1.41.3
Fe content in liver0.00.00.1-0.2-0.2-0.2-0.00.30.1-0.00.10.1-0.20.3
K content in liver0.20.20.5-0.6-0.6-0.6-0.50.70.40.3-0.3-0.1-0.30.3
Mg content in liver0.10.10.40.10.00.00.1-0.40.20.3-0.2-0.50.5-0.6
Mn content in liver2.22.53.8-1.6-1.5-1.5-1.70.61.81.9-1.9-1.81.3-1.1
Na content in liver0.50.61.40.90.90.90.9-1.2-0.5-0.30.3-0.10.6-0.8
Rb content in liver0.30.30.60.30.30.30.30.2-0.6-0.70.70.8-0.70.8
Se content in liver4.65.58.9-3.0-2.8-2.8-2.92.42.72.3-2.4-1.60.5-0.0
Sr content in liver1.00.93.00.50.40.40.4-1.30.20.6-0.5-1.21.5-1.7
Zn content in liver1.71.93.41.81.71.71.8-1.8-1.5-1.11.30.60.2-0.5
Bone: minimum diameter1.01.93.31.21.21.21.0-0.1-1.6-1.81.61.8-1.41.5
Time in familiar zone, hab. session 10.10.20.40.50.60.60.4-0.5-0.4-0.30.20.10.3-0.2
Time in novel zone, hab. session 10.30.30.7-0.4-0.5-0.5-0.40.80.1-0.10.10.4-0.80.8
Total zone transitions, hab. session 10.20.30.90.40.40.40.2-0.80.00.2-0.4-0.50.9-0.9
Total locomotion distance, hab. session 10.40.61.70.0-0.0-0.0-0.00.7-0.5-0.70.71.1-1.31.3
Locomotion velocity, hab. session 10.20.31.0-0.1-0.1-0.1-0.10.6-0.3-0.50.50.7-1.01.0
Time in familiar zone, hab. session 22.93.34.62.12.02.01.9-1.2-2.2-2.12.11.8-1.00.8
Time in novel zone, hab. session 22.42.64.2-1.5-1.5-1.5-1.30.31.92.0-2.0-2.01.7-1.5
Total zone transitions, hab. session 21.72.24.92.01.81.81.8-2.2-1.3-0.80.90.10.7-1.1
Total locomotion distance, hab. session 20.91.21.81.21.01.01.0-0.4-1.3-1.41.31.3-1.10.8
Locomotion velocity, hab. session 20.91.21.81.00.90.90.8-0.3-1.3-1.31.31.3-1.21.0
Novel to familiar place preference ratio1.31.74.90.40.20.20.40.8-1.1-1.41.51.8-2.21.9
Novelty place preference1.21.54.20.50.30.30.40.7-1.1-1.41.41.8-2.11.8
Time in novel zone, NPP test1.51.84.50.70.50.50.60.5-1.3-1.61.61.9-2.11.9
Total zone transitions, NPP test0.71.13.30.00.00.00.1-1.00.61.1-0.9-1.51.7-1.8
Total locomotion distance, NPP test0.20.20.4-0.5-0.5-0.5-0.30.10.60.6-0.5-0.60.4-0.5
Locomotion velocity, NPP test0.40.60.9-0.8-0.8-0.8-0.70.30.91.0-0.8-0.90.5-0.6
Intraocular pressure0.20.30.6-0.2-0.4-0.4-0.2-0.20.50.7-0.5-0.80.6-0.8
Delta distance traveled before/after self-admin0.90.91.71.11.11.11.3-1.0-1.1-1.01.10.7-0.2-0.0
Delta ambulatory time before/after self-admin0.40.71.40.91.01.01.2-1.0-0.9-0.80.80.4-0.0-0.2
Parametrial fat weight1.33.05.8-1.2-1.0-1.0-1.3-0.31.82.2-2.0-2.42.3-2.1
Pavlov. Cond. lever latency0.70.91.4-1.0-1.0-1.0-0.90.51.21.2-1.2-1.10.8-0.6
Pavlov. Cond. magazine entry latency2.73.45.82.42.42.42.1-2.0-2.1-1.81.71.1-0.1-0.2
Pavlov. Cond. change in total contacts1.81.92.91.41.31.31.2-0.5-1.6-1.71.71.6-1.21.1
Pavlov. Cond. index score1.92.43.61.91.91.91.7-1.4-1.8-1.61.61.2-0.40.2
Pavlov. Cond. latency score1.72.23.11.81.81.81.6-1.2-1.7-1.61.61.3-0.60.4
Pavlov. Cond. lever contacts0.80.91.31.21.11.11.0-0.8-1.1-1.11.10.9-0.40.3
Pavlov. Cond. magazine entry number2.53.25.1-2.3-2.2-2.2-2.11.72.11.8-1.8-1.30.4-0.1
Pavlov. Cond. intertrial magazine entries0.60.71.4-1.1-1.1-1.1-0.91.20.80.6-0.6-0.2-0.30.5
Pavlov. Cond. lever-magazine prob. diff.1.62.03.01.71.71.71.6-1.3-1.6-1.51.51.1-0.40.2
Pavlov. Cond. response bias1.11.42.51.61.51.51.4-1.3-1.3-1.11.10.7-0.0-0.1
Pavlov. Cond. lever latency13.318.732.5-5.7-5.5-5.5-5.45.34.63.7-3.8-2.0-0.41.3
Pavlov. Cond. magazine entry latency2.84.010.72.32.32.32.1-3.3-1.2-0.30.5-0.82.0-2.5
Pavlov. Cond. change in total contacts6.716.428.55.35.25.25.1-5.1-4.3-3.33.51.70.5-1.4
Pavlov. Cond. index score8.212.922.74.74.64.64.4-4.8-3.6-2.72.81.20.9-1.7
Pavlov. Cond. latency score6.911.021.04.44.34.34.1-4.6-3.2-2.32.50.81.2-1.9
Pavlov. Cond. lever contacts11.917.630.45.55.35.35.2-5.0-4.6-3.73.82.10.1-1.0
Pavlov. Cond. magazine entry number5.16.615.3-3.3-3.2-3.2-3.13.92.21.3-1.40.1-1.62.2
Pavlov. Cond. intertrial magazine entries0.81.83.70.70.60.60.70.6-1.3-1.61.51.9-1.91.9
Pavlov. Cond. lever-magazine prob. diff.8.212.621.84.74.64.64.4-4.6-3.6-2.72.91.20.8-1.5
Pavlov. Cond. response bias12.717.630.85.55.45.45.2-5.4-4.4-3.33.51.60.7-1.6
Time in closed arm before self-admin1.11.84.01.81.61.61.8-2.0-1.4-0.90.80.30.4-0.9
Time in closed arm after self-admin0.20.30.8-0.4-0.4-0.4-0.90.80.70.5-0.5-0.30.00.2
Time in open arm before self-admin4.55.58.4-2.9-2.7-2.7-2.92.12.82.5-2.4-1.90.9-0.4
Time in open arm after self-admin0.20.20.50.0-0.2-0.20.5-0.0-0.5-0.50.40.6-0.70.4
Bone: periosteal estimation0.61.42.11.31.31.31.0-0.6-1.4-1.51.31.3-0.70.8
Bone: periosteal perimeter0.81.52.41.61.51.51.3-1.0-1.5-1.41.31.1-0.40.3
Bone: post-yield work0.10.10.30.40.50.50.2-0.3-0.4-0.40.30.30.00.0
Progressive ratio test 1 active lever presses0.00.00.1-0.10.10.10.1-0.0-0.0-0.00.1-0.00.4-0.0
Progressive ratio test 1 breakpoint0.00.00.1-0.20.10.10.00.0-0.0-0.00.20.00.40.0
Progressive ratio test 1 inactive lever presses0.20.61.9-1.4-1.0-1.0-0.90.70.60.5-0.6-0.20.20.2
Progressive ratio test 2 active lever presses0.10.10.30.20.60.60.2-0.2-0.4-0.40.20.30.20.1
Progressive ratio test 2 breakpoint0.10.10.40.30.60.60.3-0.3-0.4-0.40.20.30.20.1
Progressive ratio test 2 inactive lever presses0.00.10.5-0.5-0.2-0.2-0.2-0.30.20.3-0.4-0.40.7-0.4
Incentive Sensitization - Responses0.10.30.70.60.90.90.3-0.4-0.6-0.50.30.40.00.1
Incentive Sensitization - Breakpoint0.10.20.70.50.80.80.2-0.5-0.4-0.30.10.10.4-0.2
Sum of active levers in priming session hrs 5-60.20.20.60.20.30.30.3-0.6-0.10.00.2-0.30.8-0.5
Progressive ratio0.30.82.50.70.60.60.6-1.30.10.5-0.7-1.01.3-1.6
Food seeking constrained by brief footshock1.51.93.21.71.41.41.7-1.4-1.8-1.61.31.2-0.70.2
Seeking ratio, punishment vs. effort0.51.22.30.70.70.70.8-0.2-1.3-1.51.51.5-1.11.2
Retroperitoneal fat weight0.52.44.2-2.0-1.9-1.9-2.11.71.71.4-1.6-0.90.10.2
Reaction time number correct0.10.20.6-0.1-0.1-0.10.1-0.30.30.5-0.4-0.60.8-0.7
Reaction time mean minus median0.10.70.90.90.90.90.8-0.4-1.0-1.00.90.9-0.60.5
Reaction time mean minus median AUC0.10.50.70.80.80.80.8-0.5-0.8-0.80.80.6-0.40.3
Reaction time num false alarms1.32.25.1-2.0-1.8-1.8-1.92.31.20.7-0.80.0-0.91.3
Reaction time num false alarms AUC0.92.14.3-2.0-1.8-1.8-1.92.11.30.9-1.0-0.2-0.61.0
Reaction time trials correct on left0.10.20.6-0.1-0.1-0.10.1-0.30.30.5-0.4-0.60.8-0.7
Reaction time trials on left0.10.20.6-0.2-0.2-0.20.0-0.30.40.5-0.5-0.70.8-0.7
Reaction time mean0.71.64.3-1.5-1.3-1.3-1.52.10.70.1-0.20.6-1.41.6
Reaction time mean AUC0.81.94.9-1.6-1.5-1.5-1.72.20.90.3-0.40.5-1.41.6
Median of all reaction times1.62.56.2-2.0-1.8-1.8-2.12.51.20.6-0.70.2-1.31.6
Reaction time omissions0.20.30.6-0.8-0.7-0.7-0.70.70.60.5-0.4-0.3-0.10.1
Reaction time false alarm rate1.42.04.1-1.8-1.7-1.7-1.92.01.30.8-0.9-0.1-0.71.0
Reaction time premature initiation rate1.62.53.61.91.81.81.7-1.1-1.9-1.81.71.6-0.90.7
Reaction time premature initiations0.41.22.01.41.41.41.3-1.1-1.3-1.21.00.8-0.30.1
Std. dev. reaction times0.31.13.00.10.20.2-0.00.9-0.7-1.11.01.5-1.71.7
Reaction time trials completed0.10.20.6-0.2-0.2-0.20.0-0.30.40.5-0.5-0.70.8-0.7
Reaction time trials AUC0.00.10.4-0.1-0.1-0.10.1-0.30.20.4-0.3-0.50.6-0.5
Run reversals in cocaine runway, females0.50.51.10.80.70.71.0-0.5-0.9-0.81.10.7-0.30.3
Run reversals in cocaine runway, males0.30.30.7-0.6-0.6-0.6-0.60.80.70.5-0.5-0.3-0.00.2
Latency to leave start box in cocaine runway0.81.02.6-1.4-1.0-1.0-1.51.61.00.7-0.1-0.2-0.40.8
Latency to leave start box in cocaine runway, F0.91.13.4-1.1-0.7-0.7-1.21.80.5-0.10.60.7-1.21.6
Latency to leave start box in cocaine runway, M1.01.01.6-1.0-0.8-0.8-1.00.31.21.2-1.0-1.30.9-0.9
Std. dev. time between licks in bursts1.42.74.61.41.31.31.2-0.1-1.9-2.12.02.2-1.91.7
Total sessions with >9 infusions1.51.94.21.42.02.01.6-1.6-1.4-1.20.70.61.0-0.3
Short access day 1 total inactive lever presses0.20.41.0-0.6-0.6-0.6-0.20.8-0.2-0.40.00.7-0.81.0
Short access day 10 total inactive lever presses0.42.47.0-2.7-2.3-2.3-1.61.81.20.8-1.1-0.2-0.20.8
Short access day 1 total infusions1.53.05.41.92.32.31.9-1.4-2.1-2.01.31.5-0.20.6
Short access day 10 total infusions0.81.42.70.91.61.61.5-1.4-1.2-0.90.70.41.2-0.4
Short access total infusions1.42.03.81.52.02.01.7-1.6-1.6-1.41.00.80.6-0.1
Short access day 1 locomotion0.50.92.21.41.51.50.8-1.1-0.5-0.30.1-0.10.8-0.7
Short access day 10 total locomotion0.20.62.00.31.01.01.0-1.0-0.4-0.10.0-0.21.4-0.7
Short access total locomotion0.20.21.10.10.40.40.3-0.60.10.2-0.0-0.51.0-0.7
One hour access (0.3 mA shock)0.30.41.50.20.60.60.6-1.0-0.3-0.00.1-0.31.2-0.8
Compulsive drug intake1.11.64.2-1.1-1.2-1.2-1.00.61.51.6-2.0-1.40.8-0.9
One hour access (shock baseline)0.51.22.71.11.41.41.2-1.6-1.0-0.71.10.11.0-0.8
Social response proportion0.20.30.7-0.6-0.9-0.9-0.50.60.50.4-0.3-0.2-0.30.2
Social responses0.30.41.1-0.4-0.5-0.5-0.51.0-0.0-0.30.20.7-1.11.1
Social time1.52.44.4-2.0-1.7-1.7-2.11.41.81.6-1.7-1.20.6-0.2
Soleus weight0.20.61.6-0.6-0.5-0.5-0.41.20.0-0.30.40.7-1.21.2
Bone: stiffness0.81.44.4-0.9-0.8-0.8-0.81.9-0.0-0.60.51.3-1.82.1
Tibialis anterior weight0.10.30.70.30.40.40.30.2-0.6-0.70.60.8-0.60.8
Time to tail flick, vehicle, before self-admin0.40.51.60.70.40.40.7-1.3-0.5-0.1-0.5-0.30.8-1.0
Time to tail flick, vehicle, after self-admin0.40.81.31.01.01.00.8-0.5-1.1-1.20.81.0-0.40.6
Time to tail flick, test, before self-admin2.52.95.01.71.31.32.2-1.1-2.2-2.12.01.9-1.40.9
Time to tail flick, test, after self-admin2.52.74.91.31.11.11.2-0.1-1.8-2.02.22.2-2.01.7
Delta time to tail flick, vehicle, before/after SA0.20.20.70.00.30.3-0.10.5-0.2-0.40.50.6-0.60.8
Delta time to tail flick, test, before/after SA0.60.82.1-0.9-0.9-0.9-1.40.91.11.0-1.0-0.70.2-0.1
Tibia length0.41.11.71.31.31.31.2-1.0-1.2-1.01.10.8-0.20.1
Ambulatory time before self-admin0.30.81.7-0.5-0.3-0.3-1.10.21.11.1-1.3-1.11.1-0.8
Ambulatory time after self-admin0.40.72.10.40.60.60.0-1.00.30.6-0.5-1.11.5-1.4
Bone: tissue strength2.02.14.0-1.0-0.9-0.9-0.9-0.21.51.8-1.8-2.01.9-1.8
Total heroin consumption0.20.20.60.30.30.30.3-0.8-0.10.10.2-0.40.7-0.7
Bone: trabecular number1.01.82.6-1.5-1.4-1.4-1.50.81.61.6-1.6-1.41.0-0.7
Bone: trabecular spacing0.40.61.70.70.70.70.9-1.3-0.20.20.2-0.70.9-1.3
Bone: trabecular thickness0.70.93.2-0.2-0.1-0.1-0.31.2-0.5-0.90.71.4-1.51.8
Bone: trabecular tissue density1.52.78.0-1.1-1.1-1.1-1.12.5-0.0-0.80.51.7-2.52.8
Water consumed over 24 hours0.10.30.4-0.7-0.7-0.7-0.60.50.60.5-0.4-0.30.00.0
Number of responses in last shaping day0.91.23.2-1.3-1.0-1.0-0.81.70.1-0.40.21.0-1.31.8