Hub : Genes

Rnf121

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Rnf121 0.09 0.07 2.3e-05 0.05 0.04 0.03 0.04 1.4e-05 1.3e-04 4.8e-04 1.3e-04
2 PL gene expression Rnf121 0.05 0.03 2.2e-04 0.04 0.02 0.01 0.03 7.5e-05 1.9e-03 1.3e-02 4.4e-04
3 Liver gene expression Rnf121 0.05 0.04 2.8e-04 0.01 0.02 0.02 0.02 2.0e-02 2.1e-03 2.6e-03 3.5e-03
4 Adipose mRNA stability Rnf121 0.05 0.04 8.7e-05 0.02 0.03 0.03 0.03 9.5e-04 1.6e-04 1.2e-04 2.1e-04
5 NAcc gene expression Rnf121 0.04 0.03 8.2e-04 0 0 -0 0 2.2e-01 8.3e-02 4.3e-01 2.9e-01
6 Adipose gene expression Rnf121 0.05 0.04 2.6e-04 0.02 0.02 0.02 0.02 4.3e-03 1.4e-03 2.3e-03 2.3e-03
7 IL gene expression Rnf121 0.23 0.15 2.5e-03 0.11 0.11 0.04 0.09 1.3e-03 1.2e-03 4.1e-02 3.3e-03
8 Brain mRNA stability Rnf121 0.32 0.16 0.0e+00 0.21 0.23 0.23 0.23 3.0e-19 1.4e-21 1.8e-21 2.8e-21
9 IL mRNA stability Rnf121 0.21 0.14 2.8e-03 0.1 0.06 0.08 0.07 2.4e-03 1.5e-02 5.6e-03 9.0e-03
10 OFC mRNA stability Rnf121 0.31 0.17 2.8e-05 0.21 0.2 0.15 0.19 1.2e-05 1.9e-05 1.7e-04 3.0e-05
11 NAcc mRNA stability Rnf121 0.15 0.09 6.2e-14 0.13 0.12 0.13 0.13 1.3e-14 3.6e-14 1.4e-14 2.0e-14
12 BLA mRNA stability Rnf121 0.16 0.1 2.1e-06 0.12 0.1 0.11 0.11 7.0e-07 5.3e-06 2.3e-06 1.6e-06
13 PL mRNA stability Rnf121 0.26 0.11 0.0e+00 0.25 0.27 0.26 0.26 8.6e-28 1.2e-29 1.4e-28 1.6e-28

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.20.3-0.5-0.60.5-0.60.50.40.4-0.40.30.40.30.2-0.3
Area under the delay curve0.20.20.5-0.7-0.70.3-0.40.2-0.0-0.10.2-0.3-0.3-0.3-0.40.5
BMI with tail1.65.28.5-1.0-0.82.0-1.72.22.42.5-2.62.92.82.72.3-2.7
BMI without tail0.20.41.51.11.2-0.80.9-0.7-0.5-0.40.30.00.1-0.1-0.4-0.0
Body weight0.31.41.71.01.2-1.21.3-1.3-1.3-1.21.2-1.0-1.0-1.1-1.21.1
Weight adjusted by age0.91.01.91.21.1-1.21.4-1.2-1.0-0.90.8-0.9-0.8-0.7-0.70.6
Bone surface0.71.31.51.11.0-1.21.1-1.2-1.2-1.21.2-1.1-1.1-1.1-1.21.0
Bone volume0.50.91.10.80.7-1.00.9-1.0-1.0-1.01.0-1.0-1.0-1.0-1.10.9
Breakpoint value in progressive ratio session0.91.01.6-0.3-0.80.9-1.21.01.01.1-1.01.01.01.01.2-1.2
Number of licking bursts1.92.35.5-2.3-2.31.9-1.91.71.51.2-1.20.80.80.90.9-0.5
Context. condit. distance diff. score1.11.35.42.32.0-1.51.4-1.2-0.9-0.70.6-0.4-0.3-0.40.0-0.2
Locomotion velocity, session 12.12.32.9-0.8-0.81.4-1.41.51.61.7-1.61.71.61.61.7-1.7
Locomotion distance, session 10.50.61.60.60.50.2-0.20.40.60.8-0.81.01.01.11.0-1.2
Locomotion velocity, session 20.80.91.80.10.00.7-0.70.81.01.1-1.11.11.11.21.1-1.4
Locomotion distance, session 20.71.02.10.40.30.5-0.40.70.91.0-1.11.21.21.41.2-1.4
Locomotion velocity, session 30.30.31.01.00.9-0.70.5-0.6-0.5-0.40.5-0.4-0.4-0.4-0.30.1
Locomotion distance, session 30.20.21.21.11.0-0.60.5-0.4-0.3-0.20.2-0.1-0.1-0.10.1-0.3
Stereotopy head waving bouts, day 30.40.50.9-0.10.1-0.50.5-0.6-0.7-0.70.7-0.8-0.8-0.8-1.00.9
Stereotopy head waving duration, day 30.10.10.30.30.6-0.20.4-0.1-0.00.0-0.10.30.30.20.0-0.2
Locomotion velocity, session 70.80.91.3-0.3-0.40.8-0.90.91.01.0-1.01.01.11.11.1-1.1
Locomotion distance, session 70.10.10.2-0.4-0.50.3-0.40.30.20.2-0.1-0.0-0.00.10.10.0
Stereotopy head waving bouts, day 71.41.64.32.12.1-1.61.6-1.4-1.2-1.00.9-0.6-0.6-0.6-0.70.3
Stereotopy head waving duration, day 71.21.44.62.12.2-1.51.5-1.3-1.1-0.80.8-0.4-0.4-0.5-0.50.1
Locomotion velocity, session 80.70.82.31.51.3-1.11.0-1.0-0.8-0.70.7-0.7-0.7-0.6-0.30.2
Locomotion distance, session 80.60.94.62.21.9-1.11.1-0.8-0.5-0.20.20.10.10.20.4-0.7
Degree of sensitization distance0.40.41.0-0.3-0.3-0.30.2-0.4-0.6-0.70.7-0.9-0.9-0.8-0.91.0
Degree of sensitization stereotypy2.62.98.62.92.8-2.12.1-1.9-1.6-1.31.3-0.9-0.9-0.9-0.80.3
Conditioned locomotion0.30.30.7-0.3-0.6-0.1-0.2-0.2-0.3-0.50.5-0.8-0.8-0.7-0.50.8
Cocaine response after cond. corrected0.60.71.9-1.4-1.21.1-1.01.00.80.7-0.70.60.60.50.4-0.3
Cocaine response after cond. not corrected1.01.11.3-1.0-0.91.1-1.01.11.11.1-1.11.11.11.01.0-0.9
Cocaine response before conditioning0.50.61.41.11.0-0.20.20.00.30.5-0.60.90.90.80.9-1.2
Saline control response3.95.26.12.12.0-2.52.3-2.5-2.4-2.42.4-2.2-2.3-2.3-2.22.0
Bone: connectivity density1.01.52.2-0.5-0.61.1-1.21.21.31.4-1.31.41.41.31.4-1.5
Bone: cortical apparent density0.30.41.7-1.3-1.20.6-0.60.40.20.00.0-0.2-0.2-0.3-0.30.5
Bone: cortical area0.50.70.90.70.6-0.90.7-0.9-0.9-0.91.0-1.0-0.9-0.9-0.80.8
Bone: cortical porosity0.30.30.40.40.3-0.60.4-0.6-0.6-0.60.6-0.6-0.7-0.5-0.50.5
Bone: cortical porosity0.30.30.50.40.4-0.60.5-0.6-0.6-0.60.6-0.7-0.7-0.5-0.60.6
Bone: cortical thickness0.50.80.9-0.6-0.60.9-0.90.90.90.9-0.90.90.90.90.9-0.9
Bone: cortical thickness0.00.00.00.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.00.00.1
Bone: cortical tissue density0.30.41.8-1.3-1.20.6-0.70.40.20.00.0-0.2-0.1-0.3-0.30.5
Condit. Reinf. active minus inactive responses2.12.32.90.91.1-1.51.6-1.6-1.7-1.71.6-1.6-1.6-1.5-1.71.6
Condit. Reinf. active-inactive response ratio3.94.25.31.21.3-2.02.0-2.1-2.2-2.32.2-2.2-2.2-2.1-2.32.2
Condit. Reinf. active responses0.91.11.80.20.4-0.90.9-1.0-1.1-1.21.2-1.2-1.2-1.1-1.41.3
Condit. Reinf. inactive responses0.30.40.7-0.8-0.60.7-0.70.70.70.6-0.60.50.50.50.4-0.4
Incentive salience index mean1.11.42.10.50.7-1.11.2-1.2-1.3-1.31.3-1.2-1.2-1.1-1.51.4
Condit. Reinf. lever presses0.00.00.1-0.3-0.10.10.10.0-0.0-0.10.0-0.0-0.00.1-0.30.2
Condit. Reinf. active minus inactive responses6.58.013.63.73.3-3.43.2-3.2-2.9-2.72.7-2.4-2.4-2.3-2.31.7
Condit. Reinf. active-inactive response ratio0.80.82.41.61.3-1.11.1-1.0-0.8-0.70.7-0.5-0.5-0.5-0.50.2
Condit. Reinf. active responses8.812.218.34.33.9-4.13.9-3.9-3.7-3.43.3-3.0-3.0-2.9-2.92.4
Condit. Reinf. inactive responses5.77.09.02.82.8-3.02.9-2.9-2.8-2.72.6-2.4-2.4-2.4-2.42.1
Condit. Reinf. lever presses8.611.727.25.24.9-4.34.2-3.9-3.4-3.02.9-2.3-2.3-2.1-2.21.4
Condit. Reinf. lever reinforcers received8.912.419.64.44.1-4.24.0-4.0-3.7-3.43.3-3.0-3.0-2.9-2.92.3
Conditioned reinforcement - actives0.00.00.20.50.4-0.1-0.1-0.00.00.1-0.00.20.20.10.0-0.3
Conditioned reinforcement - inactives0.20.30.8-0.7-0.40.00.0-0.1-0.3-0.40.4-0.6-0.6-0.6-0.90.8
Conditioned locomotion0.40.41.61.11.2-0.20.3-0.10.20.4-0.40.60.60.70.5-0.9
Patch foraging indifference point 0 sec1.01.54.81.92.2-1.51.8-1.4-1.1-0.90.9-0.5-0.5-0.5-0.70.3
Patch foraging indifference point AUC0.60.60.90.70.7-0.91.0-0.9-0.9-0.90.8-0.8-0.8-0.7-0.70.8
Delay disc. indifference point, 0s delay0.20.30.70.70.9-0.60.6-0.5-0.5-0.40.4-0.3-0.3-0.3-0.40.2
Delay disc. indifference point, 16s delay0.50.51.4-0.5-0.5-0.10.0-0.3-0.5-0.70.7-0.9-0.9-0.9-1.21.1
Delay disc. indifference point, 2s delay1.01.11.40.70.7-1.00.9-1.1-1.1-1.11.2-1.1-1.1-1.1-1.21.1
Delay disc. indifference point, 24s delay0.40.41.6-1.2-1.10.7-0.70.50.20.0-0.0-0.2-0.2-0.2-0.40.5
Delay disc. indifference point, 4s delay1.21.31.50.91.0-1.11.0-1.2-1.2-1.21.2-1.1-1.1-1.1-1.21.1
Delay disc. indifference point, 8s delay0.10.10.5-0.6-0.70.5-0.70.40.30.2-0.10.00.00.00.10.0
Indifference point function ln k0.10.10.20.30.10.0-0.00.10.20.3-0.30.40.40.30.3-0.5
Indifference point function log k0.10.10.20.30.10.0-0.00.10.20.3-0.30.40.40.30.3-0.5
Patch foraging total patch changes 0 sec0.71.14.11.72.0-1.31.6-1.1-0.9-0.70.6-0.3-0.3-0.3-0.40.0
Patch foraging total patch changes 12 sec1.31.72.41.31.4-1.41.5-1.4-1.4-1.31.3-1.3-1.2-1.1-1.01.0
Patch foraging total patch changes 18 sec0.60.81.61.21.3-1.11.2-1.0-0.9-0.80.8-0.6-0.6-0.6-0.50.5
Patch foraging total patch changes 24 sec1.41.83.01.31.6-1.51.7-1.4-1.4-1.31.2-1.2-1.2-1.0-1.21.0
Patch foraging total patch changes 6 sec0.40.62.80.91.7-0.81.4-0.8-0.6-0.50.4-0.0-0.0-0.1-0.50.1
Patch foraging time to switch 0 sec1.72.67.0-2.5-2.62.0-2.21.81.51.3-1.20.80.80.70.8-0.5
Patch foraging water rate 0 sec1.22.05.42.22.3-1.72.0-1.6-1.3-1.11.0-0.7-0.7-0.7-0.60.4
Patch foraging water rate 12 sec0.81.12.61.51.5-0.20.50.10.50.8-0.91.21.21.31.2-1.6
Patch foraging water rate 18 sec0.81.14.92.22.0-1.31.3-1.1-0.7-0.50.4-0.2-0.1-0.1-0.1-0.3
Patch foraging water rate 24 sec0.50.71.50.40.40.3-0.20.50.70.9-0.91.11.11.10.9-1.2
Patch foraging water rate 6 sec0.30.51.20.80.8-0.00.20.10.40.6-0.60.90.80.81.0-1.1
Seeking ratio, delayed vs. immediate footshock1.92.23.1-1.8-1.51.7-1.61.71.61.5-1.51.21.11.41.3-1.1
Distance traveled before self-admin1.01.01.3-0.9-0.91.1-1.01.11.11.1-1.10.90.91.01.0-0.9
Distance traveled after self-admin0.30.40.90.40.40.3-0.30.40.50.6-0.60.70.60.71.0-0.9
Extensor digitorum longus weight0.10.30.4-0.5-0.60.6-0.60.60.60.5-0.50.30.40.60.4-0.4
Bone: elastic displacement2.83.23.8-1.7-1.61.9-1.81.91.91.9-1.81.81.71.71.8-1.6
Bone: elastic work5.46.98.0-2.1-2.02.7-2.62.82.82.8-2.82.72.72.82.7-2.5
Bone: endosteal estimation2.04.45.51.81.5-2.21.9-2.2-2.2-2.22.2-2.3-2.3-2.1-2.02.0
Bone: endosteal perimeter2.14.35.32.01.8-2.32.1-2.3-2.2-2.22.2-2.1-2.1-2.0-1.91.8
Epididymis fat weight0.10.20.6-0.8-0.70.4-0.60.40.20.2-0.10.20.2-0.1-0.10.1
Delta time in closed arm before/after self-admin0.40.40.9-0.7-0.70.0-0.0-0.1-0.3-0.50.5-0.7-0.7-0.7-0.80.9
Delta time in open arm before/after self-admin3.02.94.11.82.0-1.92.0-1.8-1.7-1.61.6-1.5-1.5-1.5-1.81.3
Diff in mean of infusions in LGA sessions0.60.71.6-1.2-1.00.2-0.3-0.1-0.4-0.60.6-0.9-0.9-0.9-1.01.3
Delay discount exponential model param0.20.20.70.80.8-0.50.6-0.4-0.2-0.10.00.10.10.10.3-0.3
Extinction: sum of active levers before priming0.20.20.5-0.4-0.60.5-0.70.50.40.4-0.30.30.30.30.4-0.3
Active lever presses in extinction session 60.40.41.41.01.2-0.30.6-0.10.10.3-0.40.60.60.70.4-0.8
Bone: final force0.81.32.6-0.3-0.4-0.60.4-0.8-1.0-1.21.3-1.5-1.5-1.3-1.61.6
Bone: final moment0.81.32.4-0.0-0.1-0.70.6-0.9-1.1-1.21.3-1.5-1.4-1.3-1.51.5
Food consumed during 24 hour testing period0.80.93.41.81.8-1.21.2-1.0-0.8-0.50.5-0.3-0.2-0.2-0.2-0.2
Glucose0.50.71.3-0.0-0.10.6-0.60.70.80.9-0.90.90.91.11.2-1.1
Heart weight0.60.92.01.31.4-1.21.4-1.1-0.9-0.80.7-0.5-0.6-0.5-0.70.4
Delay discount hyperbolic model param0.10.10.40.60.6-0.20.4-0.10.00.1-0.20.30.30.30.4-0.4
Intermittent access intake day 1-15 change1.11.12.30.50.80.40.10.50.81.0-1.11.51.51.41.2-1.5
Intermittent access intake escalation1.31.32.60.30.50.5-0.10.71.01.1-1.21.61.61.51.3-1.5
Intermittent access intake escalation 20.60.61.0-0.3-0.40.7-0.50.70.80.8-0.91.01.00.90.9-0.9
Intermitt. access day 1 inactive lever presses0.40.42.1-1.5-1.00.5-0.30.30.1-0.10.1-0.4-0.4-0.3-0.50.8
Intermitt. access day 15 inactive lever presses0.20.20.80.40.9-0.50.9-0.5-0.4-0.30.20.10.1-0.1-0.30.2
Intermitt. access escalation Index0.20.20.30.10.3-0.40.4-0.4-0.5-0.50.5-0.3-0.3-0.6-0.60.6
Intermittent access day 1 total infusions1.21.41.91.30.9-1.30.9-1.3-1.3-1.31.4-1.3-1.3-1.3-0.81.1
Intermittent access day 15 total infusions0.20.20.90.90.8-0.60.5-0.5-0.4-0.30.3-0.1-0.1-0.20.00.0
Intermittent access terminal intake (last 3 days)0.30.30.91.00.6-0.80.5-0.7-0.6-0.60.6-0.4-0.4-0.5-0.00.3
Intermittent access total infusions0.40.40.70.90.3-0.80.4-0.7-0.7-0.70.8-0.6-0.6-0.7-0.10.5
Intermittent access day 1 locomotion0.20.20.40.00.1-0.30.2-0.3-0.4-0.50.5-0.6-0.6-0.6-0.50.6
Intermittent access day 15 total locomotion0.20.30.50.60.7-0.00.30.10.30.4-0.40.60.60.70.6-0.7
Intermittent access total locomotion0.10.20.50.70.7-0.50.5-0.4-0.4-0.30.3-0.2-0.2-0.1-0.10.0
Intermittent access standard deviation0.70.71.1-0.5-0.50.8-0.60.80.90.9-0.91.01.00.90.9-0.9
Left kidney weight0.51.53.71.61.9-1.51.7-1.4-1.2-1.11.0-0.7-0.7-0.6-0.90.6
Right kidney weight0.51.32.31.21.5-1.31.5-1.3-1.2-1.11.0-0.8-0.7-0.8-1.10.8
Cocaine induced anxiety0.91.04.8-2.2-1.91.2-1.10.90.70.4-0.4-0.0-0.0-0.0-0.40.4
Post-drug Anxiety1.11.32.7-0.4-0.2-0.60.6-0.8-1.0-1.21.2-1.4-1.4-1.5-1.41.6
Baseline Anxiety2.72.93.91.91.9-2.01.9-1.9-1.9-1.81.7-1.5-1.5-1.5-1.01.4
Tail length8.425.429.64.24.3-5.35.0-5.4-5.4-5.45.3-5.1-5.0-5.1-4.94.8
Length with tail4.616.719.52.93.0-4.13.9-4.3-4.4-4.44.4-4.4-4.3-4.3-4.04.2
Length without tail0.00.10.3-0.6-0.60.3-0.30.20.10.0-0.0-0.2-0.2-0.10.10.2
Times rat made contact with spout0.10.10.3-0.4-0.50.1-0.20.0-0.1-0.20.2-0.3-0.3-0.3-0.40.4
Lifetime Intake0.40.51.41.20.7-0.90.6-0.8-0.8-0.70.8-0.5-0.5-0.7-0.10.3
Liver weight, left1.11.73.7-1.0-1.5-0.2-0.4-0.4-0.8-1.11.3-1.9-1.8-1.7-1.31.9
Liver weight, right2.03.47.3-0.7-0.9-0.80.4-1.2-1.6-1.92.0-2.5-2.5-2.4-2.22.7
Locomotor activity0.10.20.90.80.9-0.40.4-0.3-0.1-0.0-0.00.00.20.20.2-0.3
Locomotor testing distance0.61.03.61.91.9-1.21.2-1.0-0.8-0.60.6-0.4-0.3-0.2-0.1-0.1
Locomotor testing rearing0.81.21.71.31.2-1.31.0-1.2-1.2-1.11.2-1.1-1.1-1.1-0.70.8
Locomotion in novel chamber2.02.54.1-0.9-0.81.4-1.21.51.61.7-1.71.92.01.71.9-1.7
Locomotion in novel chamber post-restriction0.20.20.60.80.4-0.20.0-0.00.20.3-0.30.60.50.50.4-0.7
Fecal boli incidents, locomotor time 10.60.62.2-1.3-1.51.0-1.20.90.70.5-0.40.10.10.10.3-0.0
Change in fecal boli incidents, locomotor task0.10.10.20.30.5-0.30.2-0.2-0.2-0.20.2-0.2-0.2-0.1-0.40.1
Time >=10cm from walls, locomotor time 10.70.70.90.90.9-0.90.9-0.9-0.9-0.80.8-0.7-0.7-0.7-0.90.6
Bouts of movement, locomotor time 10.80.82.30.20.6-0.71.0-0.8-0.9-0.90.8-1.0-0.9-0.7-1.51.1
Total resting periods, locomotor time 10.10.10.8-0.20.1-0.10.3-0.2-0.2-0.30.2-0.3-0.3-0.1-0.90.5
Rest time, locomotor task time 10.40.40.70.30.3-0.50.3-0.6-0.6-0.70.7-0.8-0.8-0.7-0.70.7
Distance moved, locomotor task time 10.00.00.1-0.1-0.10.2-0.10.20.20.2-0.20.30.30.20.3-0.3
Vertical activity count, locomotor time 10.00.00.1-0.1-0.1-0.00.0-0.0-0.1-0.10.1-0.3-0.3-0.2-0.30.2
Time >=10cm from walls, locomotor time 24.24.45.12.02.1-2.32.2-2.3-2.2-2.22.2-2.0-2.1-2.0-2.01.8
Bouts of movement, locomotor time 22.72.94.70.50.1-1.31.0-1.5-1.7-1.91.9-2.2-2.1-2.0-2.12.1
Total resting periods, locomotor time 21.61.73.10.0-0.3-0.80.4-1.0-1.2-1.41.5-1.8-1.8-1.6-1.71.8
Rest time, locomotor task time 21.92.24.4-1.8-2.11.7-2.01.71.51.4-1.31.01.01.01.2-0.9
Distance moved, locomotor task time 21.82.14.41.92.1-1.71.8-1.6-1.5-1.31.3-1.0-1.0-1.0-1.00.7
Vertical activity count, locomotor time 21.31.42.00.80.9-1.10.9-1.1-1.2-1.21.3-1.4-1.4-1.2-1.21.2
Light reinforcement 12.95.36.5-2.2-2.12.6-2.42.52.52.4-2.42.12.22.42.0-2.0
Light reinforcement 23.95.28.1-0.5-0.61.9-1.92.12.32.5-2.52.62.72.82.8-2.8
Bone: marrow area1.83.95.11.61.3-2.01.7-2.0-2.1-2.12.1-2.2-2.3-2.0-1.92.0
Bone: maximum diameter2.24.15.22.12.0-2.32.1-2.2-2.2-2.12.1-1.9-2.0-1.7-1.81.6
Bone: maximum force0.61.01.70.1-0.1-0.70.4-0.8-0.9-1.11.1-1.3-1.3-1.1-1.21.3
Bone: maximum moment0.40.71.30.30.1-0.70.5-0.8-0.9-0.91.0-1.1-1.1-0.9-1.01.1
Mean time between licks in bursts8.712.314.53.13.1-3.83.7-3.8-3.7-3.73.6-3.4-3.4-3.5-3.53.1
Mean num. licks in bursts1.82.24.62.12.1-1.81.8-1.7-1.5-1.31.2-0.9-0.9-1.0-1.00.6
Cd content in liver0.20.31.0-0.8-1.00.6-0.80.50.40.3-0.2-0.0-0.0-0.00.40.0
Co content in liver4.95.76.61.81.8-2.42.3-2.5-2.6-2.62.6-2.5-2.5-2.5-2.52.4
Cu content in liver2.43.03.41.31.2-1.81.6-1.8-1.8-1.91.9-1.8-1.8-1.8-1.81.7
Fe content in liver0.50.61.2-0.10.0-0.50.5-0.6-0.8-0.90.9-1.0-1.0-1.0-1.01.1
K content in liver0.30.30.9-0.9-0.80.6-0.50.60.50.4-0.40.30.30.20.1-0.1
Mg content in liver0.00.00.1-0.00.00.1-0.00.10.20.2-0.20.30.30.20.1-0.2
Mn content in liver2.83.24.2-1.8-1.92.0-2.02.01.91.8-1.81.61.61.51.7-1.5
Na content in liver0.10.10.30.40.5-0.30.3-0.2-0.2-0.10.1-0.0-0.0-0.1-0.0-0.0
Rb content in liver0.81.01.20.80.8-1.11.0-1.1-1.1-1.11.1-1.0-1.0-1.1-1.00.9
Se content in liver2.32.86.9-2.5-2.62.1-2.21.91.61.4-1.30.90.90.91.1-0.6
Sr content in liver1.61.42.90.10.10.8-0.60.91.21.3-1.41.51.51.51.4-1.7
Zn content in liver0.60.73.31.81.7-1.01.0-0.7-0.4-0.20.10.20.20.30.2-0.5
Bone: minimum diameter1.73.34.31.11.0-1.71.5-1.8-1.9-2.02.0-2.1-2.1-2.0-1.91.9
Time in familiar zone, hab. session 10.10.10.40.60.5-0.40.2-0.3-0.3-0.20.3-0.3-0.3-0.2-0.10.0
Time in novel zone, hab. session 10.10.10.3-0.6-0.40.10.0-0.1-0.2-0.30.3-0.3-0.3-0.5-0.50.6
Total zone transitions, hab. session 10.10.20.50.40.30.1-0.10.20.30.4-0.40.60.50.50.6-0.7
Total locomotion distance, hab. session 10.50.71.5-0.10.1-0.60.5-0.7-0.8-0.90.9-1.0-1.0-1.1-1.21.2
Locomotion velocity, hab. session 10.30.40.8-0.2-0.1-0.30.3-0.4-0.6-0.60.7-0.7-0.7-0.8-0.90.8
Time in familiar zone, hab. session 23.53.64.51.92.0-2.12.1-2.1-2.0-1.91.9-1.8-1.8-1.6-1.81.5
Time in novel zone, hab. session 23.73.74.7-1.3-1.41.9-1.82.02.02.0-2.02.12.21.92.1-1.9
Total zone transitions, hab. session 20.71.04.11.92.0-1.11.4-0.9-0.6-0.40.30.10.10.00.0-0.4
Total locomotion distance, hab. session 21.21.61.81.01.1-1.31.4-1.3-1.3-1.31.3-1.2-1.2-1.2-1.31.2
Locomotion velocity, hab. session 21.21.61.80.91.0-1.31.3-1.3-1.3-1.31.3-1.3-1.3-1.3-1.31.2
Novel to familiar place preference ratio2.32.43.80.20.4-1.31.4-1.5-1.6-1.71.7-1.7-1.7-1.9-1.92.0
Novelty place preference2.22.23.60.30.4-1.31.3-1.4-1.6-1.71.6-1.6-1.6-1.9-1.81.9
Time in novel zone, NPP test2.62.74.10.50.6-1.51.5-1.6-1.7-1.81.8-1.8-1.8-2.0-1.92.0
Total zone transitions, NPP test1.11.52.80.10.10.8-0.71.01.21.3-1.41.61.51.61.6-1.7
Total locomotion distance, NPP test0.30.40.5-0.5-0.30.6-0.50.60.60.6-0.70.70.70.70.5-0.6
Locomotion velocity, NPP test0.60.81.0-0.8-0.71.0-0.91.01.01.0-1.01.01.01.00.8-0.8
Intraocular pressure0.30.40.9-0.2-0.10.5-0.30.60.70.7-0.80.90.90.80.6-0.8
Delta distance traveled before/after self-admin2.72.93.81.91.8-2.01.6-1.9-1.8-1.71.8-1.6-1.6-1.7-1.31.3
Delta ambulatory time before/after self-admin1.61.72.91.71.6-1.61.3-1.5-1.4-1.31.3-1.1-1.1-1.2-0.80.8
Parametrial fat weight1.22.42.7-1.2-1.41.6-1.61.61.71.6-1.61.51.51.61.7-1.5
Pavlov. Cond. lever latency0.81.11.3-0.9-0.91.1-1.11.11.11.1-1.11.01.00.81.1-0.9
Pavlov. Cond. magazine entry latency1.82.35.22.32.0-1.91.8-1.7-1.5-1.41.3-1.1-1.1-1.0-0.90.7
Pavlov. Cond. change in total contacts2.32.42.81.31.2-1.61.5-1.7-1.7-1.61.6-1.7-1.7-1.5-1.61.5
Pavlov. Cond. index score1.62.03.61.91.7-1.71.6-1.6-1.5-1.31.3-1.2-1.2-1.0-1.10.9
Pavlov. Cond. latency score1.62.13.11.81.6-1.71.6-1.6-1.5-1.41.4-1.3-1.3-1.1-1.21.0
Pavlov. Cond. lever contacts0.70.81.01.00.9-1.01.0-1.0-0.9-0.90.9-0.9-0.8-0.6-0.80.7
Pavlov. Cond. magazine entry number1.51.94.4-2.1-1.91.7-1.71.61.41.2-1.21.01.00.80.8-0.6
Pavlov. Cond. intertrial magazine entries0.30.31.2-1.1-1.00.7-0.80.60.50.4-0.30.10.10.30.10.0
Pavlov. Cond. lever-magazine prob. diff.1.31.63.01.71.5-1.51.5-1.4-1.3-1.21.2-1.1-1.0-0.8-1.00.7
Pavlov. Cond. response bias0.70.81.61.31.1-1.11.1-1.1-1.0-0.90.9-0.8-0.8-0.6-0.60.5
Pavlov. Cond. lever latency7.810.628.9-5.4-5.24.1-4.13.73.12.6-2.51.71.81.71.6-0.8
Pavlov. Cond. magazine entry latency1.11.34.32.12.1-0.70.8-0.30.10.5-0.51.11.01.01.1-1.5
Pavlov. Cond. change in total contacts6.38.725.95.14.9-3.73.8-3.3-2.7-2.22.1-1.3-1.3-1.4-1.30.5
Pavlov. Cond. index score4.86.120.24.54.3-3.13.1-2.7-2.2-1.71.6-0.9-0.9-0.9-0.80.1
Pavlov. Cond. latency score3.84.717.24.24.0-2.72.7-2.3-1.8-1.31.2-0.5-0.6-0.5-0.4-0.3
Pavlov. Cond. lever contacts8.511.629.55.45.3-4.34.3-3.9-3.3-2.82.7-1.9-1.9-1.9-1.91.0
Pavlov. Cond. magazine entry number1.82.29.5-3.1-3.01.7-1.81.30.80.4-0.3-0.3-0.3-0.3-0.30.9
Pavlov. Cond. intertrial magazine entries1.72.23.30.40.5-1.31.2-1.4-1.5-1.61.6-1.7-1.7-1.7-1.81.8
Pavlov. Cond. lever-magazine prob. diff.4.86.119.54.44.3-3.13.1-2.7-2.2-1.71.6-0.9-1.0-1.0-0.80.2
Pavlov. Cond. response bias7.610.329.65.45.3-4.14.1-3.6-3.0-2.42.3-1.5-1.5-1.5-1.40.6
Time in closed arm before self-admin0.50.62.41.61.5-0.70.8-0.5-0.20.0-0.10.40.40.40.4-0.7
Time in closed arm after self-admin0.20.20.7-0.7-0.90.5-0.50.50.40.3-0.30.20.20.20.2-0.1
Time in open arm before self-admin3.74.08.2-2.9-2.82.4-2.32.22.01.8-1.71.41.41.51.5-0.9
Time in open arm after self-admin0.20.30.50.00.3-0.40.5-0.4-0.5-0.50.5-0.6-0.6-0.6-0.70.7
Bone: periosteal estimation1.32.63.31.51.2-1.71.4-1.7-1.7-1.71.7-1.8-1.8-1.6-1.51.5
Bone: periosteal perimeter1.22.02.71.61.4-1.61.4-1.6-1.5-1.51.5-1.3-1.4-1.4-1.11.1
Bone: post-yield work0.10.10.30.60.3-0.40.2-0.4-0.4-0.30.4-0.4-0.4-0.2-0.10.2
Progressive ratio test 1 active lever presses0.00.00.00.20.1-0.10.0-0.1-0.1-0.10.2-0.1-0.1-0.2-0.00.1
Progressive ratio test 1 breakpoint0.10.10.10.20.1-0.20.1-0.2-0.3-0.30.3-0.3-0.3-0.4-0.10.2
Progressive ratio test 1 inactive lever presses0.00.00.10.10.1-0.20.1-0.2-0.2-0.20.2-0.2-0.2-0.20.00.2
Progressive ratio test 2 active lever presses0.50.50.90.60.1-0.70.3-0.7-0.8-0.80.9-0.8-0.8-1.0-0.70.8
Progressive ratio test 2 breakpoint0.60.71.10.70.3-0.80.5-0.9-0.9-0.91.0-0.9-0.9-1.0-0.80.9
Progressive ratio test 2 inactive lever presses0.00.00.10.30.2-0.20.1-0.2-0.2-0.20.2-0.1-0.1-0.2-0.10.1
Incentive Sensitization - Responses1.01.11.41.00.6-1.10.8-1.1-1.1-1.11.2-1.1-1.1-1.1-0.91.0
Incentive Sensitization - Breakpoint0.50.60.80.90.5-0.90.5-0.8-0.8-0.80.9-0.8-0.8-0.8-0.60.6
Sum of active levers in priming session hrs 5-60.10.10.70.30.10.1-0.10.20.30.3-0.30.40.40.40.8-0.5
Progressive ratio0.40.40.8-0.00.20.5-0.20.50.60.7-0.80.90.90.90.4-0.8
Food seeking constrained by brief footshock1.82.23.21.51.6-1.71.8-1.7-1.6-1.51.5-1.1-1.2-1.3-1.41.1
Seeking ratio, punishment vs. effort1.51.92.51.10.9-1.51.1-1.5-1.5-1.51.6-1.4-1.5-1.6-1.21.3
Retroperitoneal fat weight0.20.83.8-1.7-2.00.9-1.10.60.30.1-0.0-0.3-0.2-0.4-0.40.7
Reaction time number correct0.20.30.5-0.1-0.00.4-0.30.40.50.6-0.60.60.60.70.6-0.7
Reaction time mean minus median0.40.50.60.60.8-0.80.7-0.8-0.8-0.70.7-0.7-0.7-0.7-0.70.6
Reaction time mean minus median AUC0.20.30.60.60.8-0.60.5-0.6-0.6-0.50.6-0.5-0.5-0.5-0.50.3
Reaction time num false alarms0.50.73.6-1.9-1.71.0-1.00.70.40.2-0.1-0.1-0.1-0.2-0.30.5
Reaction time num false alarms AUC0.60.83.4-1.9-1.71.1-1.20.90.60.4-0.30.10.1-0.0-0.00.3
Reaction time trials correct on left0.20.30.5-0.1-0.00.4-0.30.40.50.6-0.60.60.60.70.6-0.7
Reaction time trials on left0.20.30.6-0.1-0.10.5-0.40.50.60.6-0.70.70.70.80.7-0.7
Reaction time mean0.40.62.4-1.4-1.60.5-0.90.30.0-0.20.3-0.7-0.7-0.7-0.60.9
Reaction time mean AUC0.50.72.9-1.5-1.70.7-1.00.50.2-0.10.2-0.6-0.6-0.6-0.50.8
Median of all reaction times0.70.94.3-1.8-2.11.0-1.40.80.40.1-0.0-0.4-0.4-0.4-0.30.7
Reaction time omissions0.60.81.5-1.1-1.11.1-1.21.00.90.8-0.80.70.70.50.7-0.5
Reaction time false alarm rate0.60.83.2-1.8-1.71.0-1.20.90.60.4-0.30.00.1-0.1-0.00.3
Reaction time premature initiation rate1.92.63.21.71.7-1.81.6-1.8-1.7-1.61.6-1.5-1.5-1.5-1.51.3
Reaction time premature initiations0.70.91.81.31.3-1.11.0-1.1-1.0-0.90.9-0.7-0.7-0.8-0.80.5
Std. dev. reaction times0.91.32.2-0.0-0.1-0.70.4-0.9-1.1-1.21.3-1.5-1.5-1.5-1.41.5
Reaction time trials completed0.20.30.6-0.1-0.10.5-0.40.50.60.6-0.70.70.70.80.7-0.7
Reaction time trials AUC0.10.20.3-0.0-0.00.3-0.20.30.40.4-0.50.50.50.60.5-0.5
Run reversals in cocaine runway, females0.30.30.50.60.7-0.70.6-0.6-0.6-0.60.6-0.5-0.5-0.5-0.30.5
Run reversals in cocaine runway, males0.20.20.5-0.7-0.50.6-0.40.50.40.3-0.30.30.20.4-0.1-0.0
Latency to leave start box in cocaine runway0.40.41.8-1.0-1.30.8-1.20.70.50.4-0.2-0.00.00.0-0.00.0
Latency to leave start box in cocaine runway, F0.30.31.1-0.7-1.10.2-0.60.1-0.1-0.30.4-0.6-0.6-0.6-0.60.7
Latency to leave start box in cocaine runway, M0.90.91.8-0.8-1.01.1-1.41.11.01.0-0.90.80.90.70.7-0.8
Std. dev. time between licks in bursts3.13.74.71.31.2-1.91.8-2.0-2.1-2.12.1-2.2-2.1-2.1-2.12.0
Total sessions with >9 infusions0.60.73.92.01.4-0.80.4-0.6-0.3-0.00.10.30.30.20.7-0.8
Short access day 1 total inactive lever presses0.30.30.8-0.7-0.40.00.1-0.1-0.3-0.50.4-0.7-0.7-0.6-0.80.9
Short access day 10 total inactive lever presses0.40.51.6-1.2-0.70.9-0.70.80.70.6-0.60.40.40.50.3-0.2
Short access day 1 total infusions1.21.32.81.71.2-1.41.0-1.3-1.2-1.11.2-1.0-1.0-1.1-0.70.7
Short access day 10 total infusions0.80.92.01.41.1-1.20.8-1.1-1.0-0.91.0-0.8-0.8-0.8-0.20.6
Short access total infusions0.70.82.11.51.2-1.10.9-1.0-1.0-0.80.9-0.6-0.6-0.8-0.30.4
Short access day 1 locomotion0.50.51.20.60.40.2-0.30.40.50.7-0.70.80.80.91.1-1.1
Short access day 10 total locomotion0.30.30.5-0.1-0.10.5-0.50.50.60.6-0.60.70.70.60.6-0.7
Short access total locomotion0.10.10.30.0-0.10.3-0.50.30.40.4-0.30.30.30.40.6-0.5
One hour access (0.3 mA shock)0.10.10.80.90.7-0.30.2-0.2-0.00.1-0.00.20.20.20.3-0.5
Compulsive drug intake0.60.60.9-0.9-0.10.9-0.50.90.90.8-1.00.70.70.90.1-0.7
One hour access (shock baseline)0.50.51.51.20.5-1.00.6-0.9-0.8-0.70.8-0.5-0.5-0.7-0.10.4
Social response proportion0.10.10.6-0.8-0.20.40.00.30.30.2-0.30.50.50.1-0.2-0.0
Social responses0.20.30.7-0.5-0.3-0.10.2-0.2-0.4-0.50.5-0.5-0.5-0.7-0.80.8
Social time1.62.13.7-1.8-1.91.7-1.91.61.51.3-1.21.01.11.01.2-0.9
Soleus weight0.20.51.1-0.5-0.3-0.30.3-0.4-0.6-0.70.7-0.8-0.9-0.9-1.01.1
Bone: stiffness1.82.95.8-0.3-0.3-1.00.8-1.3-1.6-1.81.9-2.2-2.1-2.1-2.32.4
Tibialis anterior weight0.20.71.00.50.4-0.80.7-0.8-0.9-0.90.9-1.0-1.0-0.9-0.90.9
Time to tail flick, vehicle, before self-admin0.10.10.30.40.6-0.40.6-0.4-0.3-0.30.2-0.00.0-0.20.30.1
Time to tail flick, vehicle, after self-admin0.80.92.31.51.0-1.21.1-1.1-1.0-0.90.9-0.8-0.8-0.7-0.20.4
Time to tail flick, test, before self-admin2.32.23.71.41.6-1.71.9-1.7-1.6-1.51.4-1.3-1.3-1.3-1.41.2
Time to tail flick, test, after self-admin4.64.76.71.51.7-2.22.4-2.3-2.3-2.32.2-2.1-2.1-2.1-2.62.2
Delta time to tail flick, vehicle, before/after SA0.00.00.40.60.1-0.30.2-0.2-0.2-0.10.1-0.1-0.20.00.0-0.1
Delta time to tail flick, test, before/after SA0.10.10.2-0.5-0.30.3-0.20.30.30.2-0.20.20.20.2-0.1-0.1
Tibia length0.41.01.71.31.3-1.21.1-1.1-1.0-0.90.9-0.8-0.8-0.7-0.80.6
Ambulatory time before self-admin1.01.01.4-1.0-1.21.2-1.21.11.11.1-1.00.80.80.90.9-0.8
Ambulatory time after self-admin0.10.10.60.80.5-0.2-0.0-0.10.00.1-0.10.10.10.10.5-0.4
Bone: tissue strength2.92.83.9-0.7-0.61.5-1.31.61.81.8-1.92.02.02.01.9-2.0
Total heroin consumption0.20.20.91.00.8-0.40.4-0.3-0.10.1-0.10.20.20.30.5-0.5
Bone: trabecular number1.21.92.8-1.4-1.51.5-1.71.51.51.4-1.41.31.31.21.2-1.2
Bone: trabecular spacing0.40.51.10.70.80.10.10.20.50.6-0.70.90.91.00.9-1.1
Bone: trabecular thickness1.62.03.40.1-0.0-1.00.8-1.2-1.4-1.51.5-1.8-1.8-1.8-1.81.8
Bone: trabecular tissue density2.53.67.6-0.7-0.6-1.00.7-1.3-1.7-2.02.1-2.4-2.4-2.5-2.52.7
Water consumed over 24 hours0.40.40.9-0.9-0.90.8-0.80.70.70.6-0.60.50.50.50.4-0.3
Number of responses in last shaping day0.90.91.90.2-0.2-0.70.2-0.8-0.9-1.01.1-1.2-1.2-1.4-1.11.2