Hub : Genes

Rnf121

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Rnf121 0.04 0.03 2.2e-03 0.01 0.01 0.02 0.02 7.2e-03 8.4e-03 4.5e-03 6.5e-03
2 Brain gene expression Rnf121 0.06 0.05 7.1e-04 0.03 0.03 0.02 0.02 1.7e-03 1.9e-03 4.5e-03 3.6e-03
3 PL gene expression Rnf121 0.03 0.03 4.2e-03 0.02 0.01 -0 0.01 1.9e-03 2.8e-02 5.7e-01 1.2e-02
4 pVTA gene expression Rnf121 0.04 0.03 7.1e-03 0.03 0.03 0.02 0.02 2.9e-03 3.2e-03 1.0e-02 1.7e-02
5 RMTg mRNA stability Rnf121 0.16 0.11 3.2e-03 0.03 0.04 0.03 0.03 6.8e-02 3.1e-02 7.3e-02 5.3e-02
6 Adipose mRNA stability Rnf121 0.06 0.04 2.6e-05 0.03 0.04 0.03 0.03 5.4e-04 5.6e-05 1.8e-04 1.6e-04
7 Adipose gene expression Rnf121 0.04 0.03 5.7e-04 0.01 0.02 0.02 0.01 1.6e-02 2.1e-03 3.4e-03 7.7e-03
8 NAcc gene expression Rnf121 0.03 0.02 2.8e-04 0.01 0.02 0.02 0.02 3.5e-03 5.3e-04 1.3e-04 1.3e-03
9 Brain mRNA stability Rnf121 0.12 0.07 2.4e-08 0.08 0.09 0.08 0.08 3.0e-08 1.2e-08 4.0e-08 4.5e-08
10 PL mRNA stability Rnf121 0.06 0.04 4.0e-06 0.05 0.06 0.06 0.05 1.5e-06 1.2e-06 7.9e-07 3.5e-06
11 OFC mRNA stability Rnf121 0.15 0.11 5.2e-03 0.05 0.11 0.05 0.09 3.0e-02 1.5e-03 2.6e-02 4.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.30.50.70.60.60.60.50.60.50.5-0.4-0.2-0.0
Area under the delay curve0.30.41.20.80.60.60.61.10.40.10.20.30.60.9
BMI with tail0.62.26.10.30.40.40.3-1.11.21.71.5-2.2-2.2-2.5
BMI without tail0.72.05.6-1.6-1.5-1.5-1.4-2.4-0.7-0.1-0.2-0.8-1.6-1.9
Body weight0.20.91.7-1.3-1.1-1.1-1.3-1.1-1.1-0.9-1.00.60.2-0.2
Weight adjusted by age0.40.61.5-1.2-0.9-0.9-0.9-0.9-1.0-0.8-0.50.60.20.0
Bone surface0.50.91.4-1.0-1.0-1.0-1.0-0.5-1.2-1.2-1.11.10.70.6
Bone volume0.20.40.7-0.6-0.6-0.6-0.5-0.1-0.8-0.8-0.80.80.60.6
Breakpoint value in progressive ratio session0.60.81.50.80.50.51.10.71.21.21.0-1.0-0.8-0.4
Number of licking bursts2.23.56.02.42.42.42.42.22.01.71.8-1.00.10.4
Context. condit. distance diff. score2.53.15.9-2.3-2.3-2.3-2.2-2.4-1.7-1.2-1.10.4-0.9-1.1
Locomotion velocity, session 11.61.83.21.00.80.80.9-0.11.41.61.7-1.8-1.8-1.5
Locomotion distance, session 10.70.92.5-0.6-0.7-0.7-0.6-1.4-0.00.40.3-1.0-1.5-1.6
Locomotion velocity, session 20.60.72.3-0.0-0.2-0.20.0-0.90.50.80.7-1.2-1.5-1.4
Locomotion distance, session 20.60.92.8-0.4-0.4-0.4-0.3-1.30.30.70.6-1.2-1.6-1.7
Locomotion velocity, session 30.40.51.1-0.9-1.0-1.0-0.6-0.9-0.7-0.6-0.50.2-0.2-0.3
Locomotion distance, session 30.50.61.3-1.0-1.0-1.0-0.7-1.1-0.6-0.3-0.3-0.1-0.6-0.7
Stereotopy head waving bouts, day 30.30.41.20.10.20.2-0.00.7-0.3-0.5-0.60.81.11.0
Stereotopy head waving duration, day 30.20.20.6-0.6-0.4-0.4-0.8-0.7-0.4-0.3-0.60.0-0.0-0.4
Locomotion velocity, session 70.70.72.00.40.30.30.4-0.30.81.01.1-1.2-1.4-1.1
Locomotion distance, session 70.20.20.40.60.50.50.60.60.50.40.6-0.2-0.30.1
Stereotopy head waving bouts, day 72.73.15.2-2.2-2.2-2.2-2.3-2.1-1.8-1.4-1.60.7-0.3-0.6
Stereotopy head waving duration, day 72.53.05.3-2.2-2.2-2.2-2.3-2.3-1.8-1.3-1.50.6-0.4-0.8
Locomotion velocity, session 81.21.42.7-1.6-1.6-1.6-1.2-1.4-1.3-1.0-0.70.5-0.5-0.3
Locomotion distance, session 82.13.07.0-2.2-2.2-2.2-1.9-2.7-1.4-0.7-0.7-0.2-1.4-1.6
Degree of sensitization distance0.40.41.30.40.30.30.30.9-0.1-0.4-0.20.80.91.1
Degree of sensitization stereotypy4.95.38.9-3.0-3.0-3.0-2.9-2.8-2.4-1.9-2.01.0-0.4-0.7
Conditioned locomotion0.30.41.10.50.40.40.51.00.1-0.2-0.00.60.71.0
Cocaine response after cond. corrected1.01.22.11.41.41.41.21.31.21.01.0-0.50.10.3
Cocaine response after cond. not corrected0.80.91.31.01.01.00.90.51.11.11.1-1.0-0.6-0.6
Cocaine response before conditioning1.11.33.6-1.2-1.2-1.2-1.0-1.9-0.40.1-0.0-0.8-1.5-1.7
Saline control response2.73.55.2-2.0-2.0-2.0-1.9-1.0-2.3-2.3-2.22.11.41.2
Bone: connectivity density0.61.02.00.60.50.50.6-0.31.01.21.2-1.4-1.4-1.3
Bone: cortical apparent density0.91.32.61.51.51.51.41.61.10.70.6-0.20.60.7
Bone: cortical area0.10.20.2-0.4-0.5-0.5-0.3-0.2-0.5-0.5-0.40.40.20.3
Bone: cortical porosity0.10.10.3-0.0-0.1-0.10.10.3-0.2-0.3-0.40.40.50.5
Bone: cortical porosity0.20.20.3-0.3-0.3-0.3-0.20.0-0.4-0.5-0.50.60.50.5
Bone: cortical thickness0.71.21.81.11.01.01.00.31.31.41.3-1.3-1.1-0.9
Bone: cortical thickness0.00.00.1-0.1-0.2-0.2-0.2-0.1-0.2-0.2-0.30.10.10.1
Bone: cortical tissue density1.01.32.71.61.51.51.41.61.10.80.7-0.20.60.7
Condit. Reinf. active minus inactive responses1.41.62.8-1.0-0.9-0.9-1.0-0.0-1.4-1.6-1.51.71.51.3
Condit. Reinf. active-inactive response ratio2.62.85.1-1.3-1.2-1.2-1.30.0-1.8-2.1-1.92.32.01.9
Condit. Reinf. active responses0.60.82.0-0.2-0.2-0.2-0.30.6-0.7-1.0-1.01.31.41.4
Condit. Reinf. inactive responses0.40.40.70.80.80.80.80.60.80.70.6-0.5-0.1-0.1
Incentive salience index mean0.81.02.0-0.6-0.5-0.5-0.60.2-1.0-1.2-1.21.31.41.2
Condit. Reinf. lever presses0.00.00.0-0.00.10.1-0.10.0-0.0-0.0-0.20.00.20.0
Condit. Reinf. active minus inactive responses7.39.414.7-3.8-3.7-3.7-3.5-2.8-3.6-3.2-3.32.51.00.5
Condit. Reinf. active-inactive response ratio1.11.32.3-1.5-1.5-1.5-1.3-1.4-1.2-1.0-1.00.6-0.1-0.3
Condit. Reinf. active responses9.513.219.8-4.5-4.3-4.3-4.1-3.0-4.3-4.0-3.93.11.40.9
Condit. Reinf. inactive responses5.16.69.4-3.0-2.9-2.9-2.8-1.7-3.1-3.0-2.92.51.51.2
Condit. Reinf. lever presses12.317.028.6-5.3-5.2-5.2-5.0-4.5-4.6-3.9-4.02.60.4-0.4
Condit. Reinf. lever reinforcers received10.013.921.1-4.6-4.4-4.4-4.2-3.2-4.4-4.0-4.03.11.40.8
Conditioned reinforcement - actives0.10.10.90.2-0.4-0.4-0.2-0.4-0.10.00.3-0.2-0.9-0.4
Conditioned reinforcement - inactives0.71.02.11.21.31.31.11.50.50.10.20.41.11.2
Conditioned locomotion0.60.83.1-0.1-0.5-0.5-0.9-1.3-0.10.30.1-0.8-1.8-1.4
Patch foraging indifference point 0 sec1.32.44.4-2.0-1.9-1.9-2.1-1.9-1.7-1.3-1.50.7-0.1-0.5
Patch foraging indifference point AUC0.40.50.9-0.8-0.7-0.7-0.9-0.4-0.8-0.8-1.00.70.50.4
Delay disc. indifference point, 0s delay0.70.81.4-1.1-1.1-1.1-1.2-0.9-1.0-0.9-0.90.60.20.0
Delay disc. indifference point, 16s delay0.70.72.30.60.50.50.51.40.1-0.4-0.40.91.31.5
Delay disc. indifference point, 2s delay0.60.71.2-0.6-0.7-0.7-0.8-0.1-1.0-1.1-1.01.10.80.9
Delay disc. indifference point, 24s delay1.01.23.61.31.11.11.41.90.90.50.60.20.81.2
Delay disc. indifference point, 4s delay1.31.42.0-1.2-1.3-1.3-1.2-0.4-1.3-1.4-1.41.40.90.9
Delay disc. indifference point, 8s delay0.40.41.21.10.90.90.70.80.60.40.4-0.10.10.4
Indifference point function ln k0.10.10.3-0.3-0.3-0.3-0.2-0.6-0.10.10.1-0.3-0.4-0.6
Indifference point function log k0.10.10.3-0.3-0.3-0.3-0.2-0.6-0.10.10.1-0.3-0.4-0.6
Patch foraging total patch changes 0 sec1.12.13.8-1.9-1.7-1.7-2.0-1.9-1.5-1.1-1.30.5-0.3-0.7
Patch foraging total patch changes 12 sec1.01.32.2-1.3-1.2-1.2-1.5-0.8-1.3-1.3-1.31.10.50.5
Patch foraging total patch changes 18 sec0.91.42.4-1.4-1.4-1.4-1.5-1.2-1.3-1.1-1.20.80.2-0.0
Patch foraging total patch changes 24 sec0.91.52.6-1.5-1.3-1.3-1.6-0.9-1.5-1.4-1.41.20.60.4
Patch foraging total patch changes 6 sec0.61.02.4-1.3-1.0-1.0-1.6-1.2-1.0-0.8-1.00.40.0-0.4
Patch foraging time to switch 0 sec2.14.27.42.72.52.52.72.52.21.81.9-1.00.10.5
Patch foraging water rate 0 sec1.53.25.7-2.4-2.2-2.2-2.4-2.1-2.0-1.6-1.61.0-0.1-0.3
Patch foraging water rate 12 sec1.12.26.1-1.5-1.4-1.4-1.3-2.5-0.50.20.2-1.1-2.0-2.3
Patch foraging water rate 18 sec1.72.65.7-2.2-2.1-2.1-1.9-2.4-1.5-1.0-1.00.2-0.8-1.2
Patch foraging water rate 24 sec0.50.62.1-0.4-0.4-0.4-0.3-1.20.20.50.4-1.0-1.3-1.5
Patch foraging water rate 6 sec0.60.92.4-0.8-0.8-0.8-0.8-1.5-0.10.30.3-0.9-1.5-1.5
Seeking ratio, delayed vs. immediate footshock1.82.23.41.81.71.71.71.21.81.71.5-1.4-0.7-0.5
Distance traveled before self-admin0.50.71.40.30.10.10.70.00.91.11.1-1.1-1.2-0.9
Distance traveled after self-admin1.11.43.40.40.20.20.4-0.71.01.41.3-1.7-1.9-1.8
Extensor digitorum longus weight0.10.20.40.60.50.50.60.40.60.50.5-0.4-0.3-0.1
Bone: elastic displacement2.22.63.71.71.71.71.60.81.91.91.9-1.7-1.2-1.0
Bone: elastic work3.74.87.32.22.12.12.10.82.62.72.6-2.6-2.0-1.7
Bone: endosteal estimation1.53.25.0-1.8-1.8-1.8-1.6-0.7-2.1-2.2-2.02.11.41.4
Bone: endosteal perimeter1.83.85.5-2.2-2.2-2.2-2.0-1.1-2.3-2.3-2.12.01.21.1
Epididymis fat weight0.20.81.21.11.01.01.00.71.11.01.0-0.8-0.4-0.3
Delta time in closed arm before/after self-admin0.70.71.71.11.01.01.01.30.70.40.20.00.50.7
Delta time in open arm before/after self-admin2.82.74.5-1.8-1.4-1.4-2.1-1.3-2.1-2.0-1.71.71.30.7
Diff in mean of infusions in LGA sessions1.82.16.81.41.31.31.52.60.80.2-0.10.81.72.1
Delay discount exponential model param0.30.41.1-0.8-0.6-0.6-0.7-1.0-0.5-0.2-0.3-0.1-0.4-0.7
Extinction: sum of active levers before priming0.10.10.2-0.2-0.4-0.40.30.0-0.3-0.4-0.50.40.40.3
Active lever presses in extinction session 60.70.72.0-0.8-0.6-0.6-0.8-1.4-0.10.3-0.3-0.7-1.1-1.4
Bone: final force0.50.82.20.70.60.60.71.40.1-0.3-0.20.91.21.5
Bone: final moment0.30.51.80.50.40.40.51.1-0.1-0.4-0.30.81.11.3
Food consumed during 24 hour testing period1.62.24.5-1.9-1.9-1.9-1.9-2.1-1.4-1.0-1.10.3-0.6-1.0
Glucose0.20.31.10.10.00.00.0-0.50.40.60.5-0.8-1.0-0.9
Heart weight1.01.52.5-1.6-1.3-1.3-1.5-1.0-1.5-1.4-1.31.20.80.4
Delay discount hyperbolic model param0.30.30.9-0.7-0.5-0.5-0.5-1.0-0.3-0.0-0.1-0.3-0.5-0.8
Intermittent access intake day 1-15 change0.91.98.40.6-0.0-0.0-0.4-1.50.51.01.1-1.6-2.9-2.2
Intermittent access intake escalation0.81.77.70.2-0.5-0.5-0.7-1.70.10.70.8-1.3-2.8-2.1
Intermittent access intake escalation 20.50.52.80.70.00.00.0-0.80.20.40.7-0.7-1.7-1.0
Intermitt. access day 1 inactive lever presses0.72.55.02.22.22.21.82.21.30.80.6-0.01.01.1
Intermitt. access day 15 inactive lever presses0.40.72.31.51.31.30.80.60.50.40.7-0.2-0.20.2
Intermitt. access escalation Index0.00.10.10.0-0.1-0.1-0.30.1-0.2-0.3-0.20.30.30.3
Intermittent access day 1 total infusions0.71.12.1-1.2-1.5-1.5-1.0-0.8-1.2-1.2-0.90.90.20.4
Intermittent access day 15 total infusions0.40.61.4-0.4-1.0-1.0-0.9-1.2-0.7-0.4-0.00.1-1.2-0.6
Intermittent access terminal intake (last 3 days)0.50.71.3-0.4-1.1-1.1-1.0-1.1-0.9-0.7-0.40.4-1.0-0.3
Intermittent access total infusions0.60.71.3-0.4-1.1-1.1-1.0-1.1-0.9-0.8-0.70.4-0.9-0.3
Intermittent access day 1 locomotion0.20.20.50.30.10.1-0.30.3-0.4-0.6-0.40.70.50.7
Intermittent access day 15 total locomotion0.30.63.00.3-0.2-0.2-0.2-0.70.30.60.7-0.9-1.7-1.1
Intermittent access total locomotion0.20.30.70.0-0.6-0.6-0.8-0.7-0.6-0.4-0.40.2-0.9-0.2
Intermittent access standard deviation0.20.31.10.40.20.2-0.1-0.50.30.60.4-0.7-1.0-0.9
Left kidney weight0.10.51.3-1.0-0.7-0.7-1.2-0.9-0.7-0.5-0.70.20.1-0.4
Right kidney weight0.31.42.4-1.5-1.1-1.1-1.5-0.9-1.4-1.3-1.41.10.90.4
Cocaine induced anxiety2.02.85.82.32.22.21.92.41.51.00.6-0.21.11.2
Post-drug Anxiety1.71.84.01.31.51.51.02.00.4-0.2-0.60.91.81.9
Baseline Anxiety2.22.54.0-1.8-1.3-1.3-2.0-1.0-2.0-2.0-1.91.71.10.9
Tail length2.810.816.5-3.3-3.1-3.1-3.1-1.2-3.9-4.1-4.03.93.02.6
Length with tail2.08.813.7-2.9-2.7-2.7-2.8-0.9-3.5-3.7-3.63.62.82.5
Length without tail0.10.30.7-0.3-0.2-0.2-0.30.2-0.5-0.6-0.70.80.80.7
Times rat made contact with spout0.20.20.50.50.40.40.40.70.2-0.0-0.00.30.60.6
Lifetime Intake0.91.12.0-0.8-1.4-1.4-1.3-1.4-1.1-0.9-0.80.4-1.0-0.4
Liver weight, left0.30.51.30.50.40.40.61.00.0-0.3-0.10.71.01.2
Liver weight, right0.40.72.30.30.30.30.41.1-0.2-0.6-0.41.11.21.5
Locomotor activity0.40.61.3-1.0-0.9-0.9-1.1-1.2-0.7-0.4-0.50.0-0.5-0.6
Locomotor testing distance1.12.03.4-1.9-1.8-1.8-1.8-1.7-1.5-1.2-1.20.6-0.3-0.4
Locomotor testing rearing0.61.21.8-1.3-1.3-1.3-1.2-0.8-1.3-1.2-1.21.00.30.4
Locomotion in novel chamber1.11.42.20.91.01.01.20.21.41.51.4-1.5-1.1-1.2
Locomotion in novel chamber post-restriction0.30.41.4-0.8-0.8-0.8-0.7-1.2-0.5-0.20.0-0.2-0.5-0.8
Fecal boli incidents, locomotor time 10.91.22.51.41.11.11.51.61.31.01.2-0.5-0.10.5
Change in fecal boli incidents, locomotor task0.20.20.8-0.3-0.2-0.2-0.9-0.5-0.6-0.5-0.90.30.2-0.0
Time >=10cm from walls, locomotor time 10.70.71.6-0.7-0.6-0.6-1.1-0.6-1.0-1.0-1.30.90.70.4
Bouts of movement, locomotor time 10.50.61.7-0.30.00.0-0.40.5-0.7-0.9-0.71.21.31.2
Total resting periods, locomotor time 10.20.20.60.30.60.60.10.6-0.1-0.2-0.10.50.80.7
Rest time, locomotor task time 10.20.20.50.60.70.7-0.10.3-0.2-0.3-0.20.40.30.6
Distance moved, locomotor task time 10.10.10.4-0.5-0.6-0.60.1-0.20.20.30.2-0.3-0.4-0.4
Vertical activity count, locomotor time 10.00.10.2-0.3-0.4-0.40.00.2-0.0-0.1-0.20.20.30.3
Time >=10cm from walls, locomotor time 22.53.76.3-1.6-1.3-1.3-2.2-1.0-2.4-2.5-2.52.31.81.4
Bouts of movement, locomotor time 21.11.84.7-0.3-0.3-0.3-0.40.8-1.2-1.7-1.42.01.92.2
Total resting periods, locomotor time 20.71.13.80.1-0.0-0.00.11.1-0.7-1.1-0.91.61.61.9
Rest time, locomotor task time 21.62.13.41.81.51.51.91.51.71.51.6-1.1-0.6-0.1
Distance moved, locomotor task time 21.72.03.8-1.6-1.5-1.5-1.9-1.5-1.7-1.5-1.61.00.40.0
Vertical activity count, locomotor time 20.50.71.4-0.5-0.6-0.6-0.90.0-0.9-1.1-1.21.10.81.0
Light reinforcement 11.53.75.52.02.02.02.01.02.32.32.3-2.0-1.4-1.1
Light reinforcement 21.93.07.40.50.40.40.6-1.11.42.01.9-2.5-2.7-2.7
Bone: marrow area1.32.74.3-1.6-1.6-1.6-1.4-0.5-2.0-2.1-1.92.01.41.4
Bone: maximum diameter1.73.24.6-2.1-2.1-2.1-1.9-1.3-2.1-2.0-1.91.70.80.7
Bone: maximum force0.10.30.70.50.30.30.60.90.1-0.10.00.40.50.9
Bone: maximum moment0.10.10.40.20.10.10.40.50.0-0.20.00.30.30.6
Mean time between licks in bursts3.58.613.1-3.0-2.9-2.9-2.8-1.2-3.5-3.6-3.63.32.52.1
Mean num. licks in bursts2.03.15.1-2.3-2.2-2.2-2.2-2.0-2.0-1.6-1.81.00.1-0.2
Cd content in liver0.30.31.00.30.20.20.40.8-0.1-0.4-0.10.70.71.0
Co content in liver2.32.74.1-1.6-1.5-1.5-1.6-0.5-1.9-2.0-2.02.01.41.3
Cu content in liver1.21.52.6-1.0-0.9-0.9-1.0-0.1-1.4-1.5-1.51.61.41.3
Fe content in liver0.00.00.10.20.20.20.00.30.1-0.0-0.10.10.20.3
K content in liver0.20.20.50.60.60.60.50.70.40.30.3-0.10.30.3
Mg content in liver0.10.10.4-0.1-0.0-0.0-0.1-0.40.20.30.2-0.5-0.5-0.6
Mn content in liver2.22.53.81.61.51.51.70.61.81.91.9-1.8-1.3-1.1
Na content in liver0.50.61.4-0.9-0.9-0.9-0.9-1.2-0.5-0.3-0.3-0.1-0.6-0.8
Rb content in liver0.30.30.6-0.3-0.3-0.3-0.30.2-0.6-0.7-0.70.80.70.8
Se content in liver4.65.58.93.02.82.82.92.42.72.32.4-1.6-0.5-0.0
Sr content in liver1.00.93.0-0.5-0.4-0.4-0.4-1.30.20.60.5-1.2-1.5-1.7
Zn content in liver1.71.93.4-1.8-1.7-1.7-1.8-1.8-1.5-1.1-1.30.6-0.2-0.5
Bone: minimum diameter1.01.93.3-1.2-1.2-1.2-1.0-0.1-1.6-1.8-1.61.81.41.5
Time in familiar zone, hab. session 10.20.20.4-0.5-0.6-0.6-0.4-0.5-0.4-0.3-0.20.1-0.3-0.2
Time in novel zone, hab. session 10.30.30.70.40.50.50.40.80.1-0.1-0.10.40.80.8
Total zone transitions, hab. session 10.20.30.9-0.4-0.4-0.4-0.2-0.80.00.20.4-0.5-0.9-0.9
Total locomotion distance, hab. session 10.40.61.7-0.00.00.00.00.7-0.5-0.7-0.71.11.31.3
Locomotion velocity, hab. session 10.20.31.00.10.10.10.10.6-0.3-0.5-0.50.71.01.0
Time in familiar zone, hab. session 23.13.34.6-2.1-2.0-2.0-1.9-1.2-2.2-2.1-2.11.81.00.8
Time in novel zone, hab. session 22.62.64.21.51.51.51.30.31.92.02.0-2.0-1.7-1.5
Total zone transitions, hab. session 21.72.24.9-2.0-1.8-1.8-1.8-2.2-1.3-0.8-0.90.1-0.7-1.1
Total locomotion distance, hab. session 20.91.21.8-1.2-1.0-1.0-1.0-0.4-1.3-1.4-1.31.31.10.8
Locomotion velocity, hab. session 20.91.21.8-1.0-0.9-0.9-0.8-0.3-1.3-1.3-1.31.31.21.0
Novel to familiar place preference ratio1.51.74.9-0.4-0.2-0.2-0.40.8-1.1-1.4-1.51.82.21.9
Novelty place preference1.41.54.3-0.5-0.3-0.3-0.40.7-1.1-1.4-1.41.82.11.8
Time in novel zone, NPP test1.71.84.5-0.7-0.5-0.5-0.60.5-1.3-1.6-1.61.92.11.9
Total zone transitions, NPP test0.71.13.3-0.0-0.0-0.0-0.1-1.00.61.10.9-1.5-1.7-1.8
Total locomotion distance, NPP test0.20.20.40.50.50.50.30.10.60.60.5-0.6-0.4-0.5
Locomotion velocity, NPP test0.40.60.90.80.80.80.70.30.91.00.8-0.9-0.5-0.6
Intraocular pressure0.20.30.60.20.40.40.2-0.20.50.70.5-0.8-0.6-0.8
Delta distance traveled before/after self-admin0.90.91.7-1.1-1.1-1.1-1.3-1.0-1.1-1.0-1.10.70.2-0.0
Delta ambulatory time before/after self-admin0.50.71.4-0.9-1.0-1.0-1.2-1.0-0.9-0.8-0.80.40.0-0.2
Parametrial fat weight1.33.05.81.21.01.01.3-0.31.82.22.0-2.4-2.3-2.1
Pavlov. Cond. lever latency0.70.91.41.01.01.00.90.51.21.21.2-1.1-0.8-0.6
Pavlov. Cond. magazine entry latency2.73.45.8-2.4-2.4-2.4-2.1-2.0-2.1-1.8-1.71.10.1-0.2
Pavlov. Cond. change in total contacts1.81.92.9-1.4-1.3-1.3-1.2-0.5-1.6-1.7-1.71.61.21.1
Pavlov. Cond. index score1.92.43.6-1.9-1.9-1.9-1.7-1.4-1.8-1.6-1.61.20.40.2
Pavlov. Cond. latency score1.72.23.1-1.8-1.8-1.8-1.6-1.2-1.7-1.6-1.61.30.60.4
Pavlov. Cond. lever contacts0.80.91.3-1.2-1.1-1.1-1.0-0.8-1.1-1.1-1.10.90.40.3
Pavlov. Cond. magazine entry number2.53.25.12.32.22.22.11.72.11.81.8-1.3-0.4-0.1
Pavlov. Cond. intertrial magazine entries0.60.71.41.11.11.10.91.20.80.60.6-0.20.30.5
Pavlov. Cond. lever-magazine prob. diff.1.62.03.0-1.7-1.7-1.7-1.6-1.3-1.6-1.5-1.51.10.40.2
Pavlov. Cond. response bias1.11.42.5-1.6-1.5-1.5-1.4-1.3-1.3-1.1-1.10.70.0-0.1
Pavlov. Cond. lever latency13.818.732.55.75.55.55.45.34.63.73.8-2.00.41.3
Pavlov. Cond. magazine entry latency3.34.010.7-2.3-2.3-2.3-2.1-3.3-1.2-0.3-0.5-0.8-2.0-2.5
Pavlov. Cond. change in total contacts10.216.428.5-5.3-5.2-5.2-5.1-5.1-4.3-3.3-3.51.7-0.5-1.4
Pavlov. Cond. index score9.612.922.7-4.7-4.6-4.6-4.4-4.8-3.6-2.7-2.81.2-0.9-1.7
Pavlov. Cond. latency score8.311.021.0-4.4-4.3-4.3-4.1-4.6-3.2-2.3-2.50.8-1.2-1.9
Pavlov. Cond. lever contacts12.817.630.4-5.5-5.3-5.3-5.2-5.0-4.6-3.7-3.82.1-0.1-1.0
Pavlov. Cond. magazine entry number5.36.615.33.33.23.23.13.92.21.31.40.11.62.2
Pavlov. Cond. intertrial magazine entries1.21.83.7-0.7-0.6-0.6-0.70.6-1.3-1.6-1.51.91.91.9
Pavlov. Cond. lever-magazine prob. diff.9.412.621.8-4.7-4.6-4.6-4.4-4.6-3.6-2.7-2.91.2-0.8-1.5
Pavlov. Cond. response bias12.917.630.8-5.5-5.4-5.4-5.2-5.4-4.4-3.3-3.51.6-0.7-1.6
Time in closed arm before self-admin1.41.84.0-1.8-1.6-1.6-1.8-2.0-1.4-0.9-0.80.3-0.4-0.9
Time in closed arm after self-admin0.30.30.80.40.40.40.90.80.70.50.5-0.3-0.00.2
Time in open arm before self-admin5.05.58.42.92.72.72.92.12.82.52.4-1.9-0.9-0.4
Time in open arm after self-admin0.20.20.5-0.00.20.2-0.5-0.0-0.5-0.5-0.40.60.70.4
Bone: periosteal estimation0.71.42.1-1.3-1.3-1.3-1.0-0.6-1.4-1.5-1.31.30.70.8
Bone: periosteal perimeter0.91.52.4-1.6-1.5-1.5-1.3-1.0-1.5-1.4-1.31.10.40.3
Bone: post-yield work0.10.10.3-0.4-0.5-0.5-0.2-0.3-0.4-0.4-0.30.3-0.00.0
Progressive ratio test 1 active lever presses0.00.00.10.1-0.1-0.1-0.1-0.0-0.0-0.0-0.1-0.0-0.4-0.0
Progressive ratio test 1 breakpoint0.00.00.10.2-0.1-0.1-0.00.0-0.0-0.0-0.20.0-0.40.0
Progressive ratio test 1 inactive lever presses0.40.61.91.41.01.00.90.70.60.50.6-0.2-0.20.2
Progressive ratio test 2 active lever presses0.10.10.3-0.2-0.6-0.6-0.2-0.2-0.4-0.4-0.20.3-0.20.1
Progressive ratio test 2 breakpoint0.10.10.4-0.3-0.6-0.6-0.3-0.3-0.4-0.4-0.20.3-0.20.1
Progressive ratio test 2 inactive lever presses0.10.10.50.50.20.20.2-0.30.20.30.4-0.4-0.7-0.4
Incentive Sensitization - Responses0.20.30.7-0.6-0.9-0.9-0.3-0.4-0.6-0.5-0.30.4-0.00.1
Incentive Sensitization - Breakpoint0.20.20.7-0.5-0.8-0.8-0.2-0.5-0.4-0.3-0.10.1-0.4-0.2
Sum of active levers in priming session hrs 5-60.20.20.6-0.2-0.3-0.3-0.3-0.6-0.10.0-0.2-0.3-0.8-0.5
Progressive ratio0.50.82.5-0.7-0.6-0.6-0.6-1.30.10.50.7-1.0-1.2-1.6
Food seeking constrained by brief footshock1.61.93.2-1.7-1.4-1.4-1.7-1.4-1.8-1.6-1.31.20.70.2
Seeking ratio, punishment vs. effort0.81.22.3-0.7-0.7-0.7-0.8-0.2-1.3-1.5-1.51.51.11.2
Retroperitoneal fat weight0.62.44.22.01.91.92.11.71.71.41.6-0.9-0.10.2
Reaction time number correct0.10.20.60.10.10.1-0.1-0.30.30.50.4-0.6-0.8-0.7
Reaction time mean minus median0.30.70.9-0.9-0.9-0.9-0.8-0.4-1.0-1.0-0.90.90.60.5
Reaction time mean minus median AUC0.20.50.7-0.8-0.8-0.8-0.8-0.5-0.8-0.8-0.80.60.40.3
Reaction time num false alarms1.62.25.12.01.81.81.92.31.20.70.80.00.91.3
Reaction time num false alarms AUC1.32.14.32.01.81.81.92.11.30.91.0-0.20.61.0
Reaction time trials correct on left0.10.20.60.10.10.1-0.1-0.30.30.50.4-0.6-0.8-0.7
Reaction time trials on left0.10.20.60.20.20.2-0.0-0.30.40.50.5-0.7-0.8-0.7
Reaction time mean1.01.64.31.51.31.31.52.10.70.10.20.61.41.6
Reaction time mean AUC1.21.94.91.61.51.51.72.20.90.30.40.51.41.6
Median of all reaction times1.82.56.22.01.81.82.12.51.20.60.70.21.31.6
Reaction time omissions0.20.30.60.80.70.70.70.70.60.50.4-0.30.10.1
Reaction time false alarm rate1.42.04.11.81.71.71.92.01.30.80.9-0.10.71.0
Reaction time premature initiation rate1.82.53.6-1.9-1.8-1.8-1.7-1.1-1.9-1.8-1.71.60.90.7
Reaction time premature initiations0.71.22.0-1.4-1.4-1.4-1.3-1.1-1.3-1.2-1.00.80.30.1
Std. dev. reaction times0.61.13.0-0.1-0.2-0.20.00.9-0.7-1.1-1.01.51.71.7
Reaction time trials completed0.10.20.60.20.20.2-0.0-0.30.40.50.5-0.7-0.8-0.7
Reaction time trials AUC0.10.10.40.10.10.1-0.1-0.30.20.40.3-0.5-0.6-0.5
Run reversals in cocaine runway, females0.50.51.1-0.8-0.7-0.7-1.0-0.5-0.9-0.8-1.10.70.30.3
Run reversals in cocaine runway, males0.30.30.70.60.60.60.60.80.70.50.5-0.30.00.2
Latency to leave start box in cocaine runway0.91.02.61.41.01.01.51.61.00.70.1-0.20.40.8
Latency to leave start box in cocaine runway, F1.01.13.41.10.70.71.21.80.5-0.1-0.60.71.21.6
Latency to leave start box in cocaine runway, M1.01.01.61.00.80.81.00.31.21.21.0-1.3-0.9-0.9
Std. dev. time between licks in bursts2.02.74.6-1.4-1.3-1.3-1.2-0.1-1.9-2.1-2.02.21.91.7
Total sessions with >9 infusions1.61.94.2-1.4-2.0-2.0-1.6-1.6-1.4-1.2-0.70.6-1.0-0.3
Short access day 1 total inactive lever presses0.30.41.00.60.60.60.20.8-0.2-0.4-0.00.70.81.0
Short access day 10 total inactive lever presses1.02.47.02.72.32.31.61.81.20.81.1-0.20.20.8
Short access day 1 total infusions2.23.05.4-1.9-2.3-2.3-1.9-1.4-2.1-2.0-1.31.50.20.6
Short access day 10 total infusions1.11.42.7-0.9-1.6-1.6-1.5-1.4-1.2-0.9-0.70.4-1.2-0.4
Short access total infusions1.62.03.8-1.5-2.0-2.0-1.7-1.6-1.6-1.4-1.00.8-0.6-0.1
Short access day 1 locomotion0.70.92.2-1.4-1.5-1.5-0.8-1.1-0.5-0.3-0.1-0.1-0.8-0.7
Short access day 10 total locomotion0.30.62.0-0.3-1.0-1.0-1.0-1.0-0.4-0.1-0.0-0.2-1.4-0.7
Short access total locomotion0.20.21.1-0.1-0.4-0.4-0.3-0.60.10.20.0-0.5-1.0-0.7
One hour access (0.3 mA shock)0.30.41.5-0.2-0.6-0.6-0.6-1.0-0.3-0.0-0.1-0.3-1.2-0.8
Compulsive drug intake1.41.64.21.11.21.21.00.61.51.62.0-1.4-0.8-0.9
One hour access (shock baseline)0.81.22.7-1.1-1.4-1.4-1.2-1.6-1.0-0.7-1.10.1-1.0-0.8
Social response proportion0.30.30.70.60.90.90.50.60.50.40.3-0.20.30.2
Social responses0.30.41.10.40.50.50.51.0-0.0-0.3-0.20.71.11.1
Social time1.82.44.42.01.71.72.11.41.81.61.7-1.2-0.6-0.2
Soleus weight0.20.61.60.60.50.50.41.20.0-0.3-0.40.71.21.2
Bone: stiffness0.91.44.40.90.80.80.81.9-0.0-0.6-0.51.31.82.1
Tibialis anterior weight0.10.30.7-0.3-0.4-0.4-0.30.2-0.6-0.7-0.60.80.60.8
Time to tail flick, vehicle, before self-admin0.40.51.6-0.7-0.4-0.4-0.7-1.3-0.5-0.10.5-0.3-0.8-1.0
Time to tail flick, vehicle, after self-admin0.60.81.3-1.0-1.0-1.0-0.8-0.5-1.1-1.2-0.81.00.40.6
Time to tail flick, test, before self-admin2.82.95.0-1.7-1.3-1.3-2.2-1.1-2.2-2.1-2.01.91.40.9
Time to tail flick, test, after self-admin2.62.74.9-1.3-1.1-1.1-1.2-0.1-1.8-2.0-2.22.22.01.7
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.0-0.3-0.30.10.5-0.2-0.4-0.50.60.60.8
Delta time to tail flick, test, before/after SA0.80.82.10.90.90.91.40.91.11.01.0-0.7-0.2-0.1
Tibia length0.41.11.7-1.3-1.3-1.3-1.2-1.0-1.2-1.0-1.10.80.20.1
Ambulatory time before self-admin0.50.81.70.50.30.31.10.21.11.11.3-1.1-1.1-0.8
Ambulatory time after self-admin0.60.72.1-0.4-0.6-0.6-0.0-1.00.30.60.5-1.1-1.5-1.4
Bone: tissue strength2.12.14.01.00.90.90.9-0.21.51.81.8-2.0-1.9-1.8
Total heroin consumption0.20.20.6-0.3-0.3-0.3-0.3-0.8-0.10.1-0.2-0.4-0.7-0.7
Bone: trabecular number1.11.82.61.51.41.41.50.81.61.61.6-1.4-1.0-0.7
Bone: trabecular spacing0.50.61.7-0.7-0.7-0.7-0.9-1.3-0.20.2-0.2-0.7-0.9-1.3
Bone: trabecular thickness0.80.93.20.20.10.10.31.2-0.5-0.9-0.71.41.51.8
Bone: trabecular tissue density1.82.78.01.11.11.11.12.5-0.0-0.8-0.51.72.52.8
Water consumed over 24 hours0.20.30.40.70.70.70.60.50.60.50.4-0.3-0.00.0
Number of responses in last shaping day1.11.23.21.31.01.00.81.70.1-0.4-0.21.01.31.8