Hub : Genes

Lrrc32

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS NM_001170434.2 0.03 0.02 9.8e-03 0.02 0.01 0.01 0.01 5.0e-03 7.4e-02 3.1e-02 2.6e-02
2 pVTA alternative TSS NM_001170434.2 0.04 0.03 6.2e-03 0.03 0.02 0.03 0.02 1.0e-03 5.6e-03 3.1e-03 5.3e-03
3 Adipose gene expression Lrrc32 0.05 0.04 1.4e-04 0.03 0.02 0.02 0.02 1.7e-04 3.8e-03 3.2e-03 2.6e-03
4 PL gene expression Lrrc32 0.03 0.02 1.9e-03 0.02 0.01 0.01 0.02 4.4e-03 7.3e-03 5.6e-02 6.2e-03
5 Liver gene expression Lrrc32 0.09 0.09 3.9e-04 0.03 0.02 0.03 0.02 2.8e-04 1.5e-03 5.1e-04 1.6e-03
6 IC gene expression Lrrc32 0.61 0.24 1.5e-05 0.04 0.09 0.12 0.08 6.4e-03 1.4e-04 7.5e-06 3.6e-04
7 NAcc gene expression Lrrc32 0.02 0.01 8.4e-03 0.01 0.01 0 0.01 6.0e-03 7.1e-03 6.6e-02 3.4e-02
8 Brain isoform ratio XM_006229747.5 0.04 0.03 8.8e-03 -0 -0 0 -0 3.9e-01 6.0e-01 3.4e-01 7.1e-01
9 Adipose alternative TSS XM_039106013.2 0.03 0.03 9.9e-03 0 0 0 0 7.4e-02 9.6e-02 3.0e-01 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.31.4-0.3-0.90.30.00.31.20.30.50.6
Area under the delay curve0.10.20.60.10.8-0.50.5-0.5-0.3-0.20.3-0.2
BMI with tail1.03.68.60.3-0.32.3-2.22.4-1.42.9-1.81.8
BMI without tail0.94.88.41.10.32.6-2.32.40.02.9-2.72.9
Body weight1.25.111.01.00.12.4-2.12.5-1.13.3-2.92.7
Weight adjusted by age0.20.61.00.90.90.5-0.70.70.00.7-1.00.9
Bone surface1.02.16.11.81.2-0.71.1-0.92.5-0.7-1.21.8
Bone volume0.51.03.51.10.80.00.20.01.9-0.0-0.91.6
Breakpoint value in progressive ratio session0.40.81.7-1.1-1.20.2-0.30.2-1.10.31.2-1.3
Number of licking bursts1.23.75.4-2.0-2.22.2-1.92.1-2.22.31.3-0.0
Context. condit. distance diff. score1.51.82.81.31.5-1.61.7-1.41.6-1.4-0.6-0.3
Locomotion velocity, session 10.60.62.2-0.50.3-0.60.1-0.6-0.9-1.00.8-1.5
Locomotion distance, session 10.70.92.10.50.9-1.51.0-1.2-0.5-1.2-0.2-1.1
Locomotion velocity, session 20.20.21.00.21.0-0.30.1-0.4-0.1-0.6-0.1-0.0
Locomotion distance, session 20.20.30.60.50.8-0.60.2-0.60.1-0.7-0.3-0.4
Locomotion velocity, session 30.30.31.10.30.6-0.60.3-0.5-0.1-0.6-0.1-1.1
Locomotion distance, session 30.70.81.70.41.0-1.10.7-1.20.2-1.30.2-1.2
Stereotopy head waving bouts, day 30.50.61.1-0.7-1.00.9-0.70.9-0.40.90.30.5
Stereotopy head waving duration, day 30.30.31.00.6-0.1-0.60.7-0.51.0-0.5-0.5-0.1
Locomotion velocity, session 70.50.51.3-0.90.20.6-0.60.4-0.90.31.2-0.8
Locomotion distance, session 70.20.30.90.00.60.5-0.90.4-0.90.50.2-0.3
Stereotopy head waving bouts, day 71.51.73.90.60.6-1.52.0-1.61.5-1.8-0.1-0.4
Stereotopy head waving duration, day 71.72.13.61.31.0-1.61.9-1.61.8-1.7-1.00.3
Locomotion velocity, session 81.72.14.01.22.0-1.61.6-1.51.7-1.70.00.4
Locomotion distance, session 81.31.93.11.31.8-1.71.7-1.51.0-1.6-0.7-0.4
Degree of sensitization distance0.91.02.20.3-0.01.2-1.01.2-0.51.4-0.71.5
Degree of sensitization stereotypy3.33.77.21.21.3-2.42.7-2.41.9-2.5-0.7-0.3
Conditioned locomotion0.20.20.8-0.40.0-0.10.3-0.20.3-0.40.9-0.8
Cocaine response after cond. corrected0.81.25.1-0.9-0.21.0-0.71.0-2.21.20.8-0.2
Cocaine response after cond. not corrected0.30.42.9-0.4-0.10.10.20.0-1.70.40.5-0.5
Cocaine response before conditioning1.31.63.20.8-0.1-1.81.7-1.81.2-1.6-0.6-0.3
Saline control response1.21.63.51.71.1-1.21.3-1.20.9-0.9-1.91.0
Bone: connectivity density0.40.63.30.2-0.3-0.40.8-0.71.8-0.60.50.6
Bone: cortical apparent density0.61.01.6-1.0-1.11.1-1.31.1-1.01.00.80.3
Bone: cortical area0.40.71.71.00.20.3-0.50.40.60.9-1.31.3
Bone: cortical porosity0.80.92.00.20.5-1.41.2-1.20.1-1.20.2-1.2
Bone: cortical porosity0.80.91.70.10.4-1.31.2-1.20.3-1.30.2-1.1
Bone: cortical thickness0.50.82.0-0.5-1.10.8-1.01.0-1.01.40.4-0.2
Bone: cortical thickness0.10.20.9-0.00.4-0.40.20.0-0.90.2-0.1-0.3
Bone: cortical tissue density0.60.91.4-1.0-1.11.0-1.21.0-1.00.90.90.1
Condit. Reinf. active minus inactive responses0.60.71.30.40.11.0-0.80.9-0.11.1-1.01.1
Condit. Reinf. active-inactive response ratio0.80.92.61.00.20.5-0.50.40.90.7-1.51.6
Condit. Reinf. active responses0.40.51.2-0.1-0.11.1-0.91.0-0.51.1-0.50.6
Condit. Reinf. inactive responses0.20.30.8-0.7-0.10.5-0.40.5-0.90.30.5-0.6
Incentive salience index mean0.40.50.90.30.50.9-0.80.9-0.20.9-0.61.0
Condit. Reinf. lever presses0.10.10.7-0.10.80.3-0.10.30.0-0.10.20.5
Condit. Reinf. active minus inactive responses3.45.310.63.22.9-2.02.1-1.71.5-1.4-3.31.5
Condit. Reinf. active-inactive response ratio0.40.62.01.11.4-0.60.6-0.4-0.3-0.3-1.10.1
Condit. Reinf. active responses5.98.517.14.13.7-2.22.3-2.22.2-1.8-4.12.5
Condit. Reinf. inactive responses3.45.19.53.02.6-1.51.5-1.72.3-1.5-3.12.4
Condit. Reinf. lever presses13.820.029.45.44.9-4.54.6-4.74.5-4.1-4.72.2
Condit. Reinf. lever reinforcers received6.69.318.24.23.8-2.52.5-2.42.3-2.0-4.32.3
Conditioned reinforcement - actives0.31.12.00.81.1-1.31.4-1.30.8-1.2-0.3-0.4
Conditioned reinforcement - inactives0.10.41.1-0.8-0.0-0.40.6-0.50.2-0.51.1-0.8
Conditioned locomotion1.92.85.50.91.6-2.22.3-2.20.5-2.0-0.0-1.6
Patch foraging indifference point 0 sec2.26.39.33.02.0-2.72.8-2.53.1-2.2-2.71.1
Patch foraging indifference point AUC0.10.31.60.40.30.3-0.30.30.50.3-0.61.3
Delay disc. indifference point, 0s delay0.60.71.51.21.2-0.60.7-0.7-0.0-0.6-1.20.1
Delay disc. indifference point, 16s delay0.20.21.0-0.40.4-0.40.1-0.4-0.3-0.31.0-0.5
Delay disc. indifference point, 2s delay1.21.42.51.41.3-1.61.4-1.30.6-1.2-0.9-0.1
Delay disc. indifference point, 24s delay0.50.81.4-1.1-0.61.0-1.00.9-0.80.91.20.2
Delay disc. indifference point, 4s delay0.80.93.81.21.9-0.30.3-0.5-0.8-0.2-1.20.3
Delay disc. indifference point, 8s delay0.10.20.40.10.5-0.50.7-0.60.5-0.20.40.2
Indifference point function ln k0.61.93.50.90.8-1.91.9-1.90.8-1.7-0.2-1.2
Indifference point function log k0.61.93.50.90.8-1.91.9-1.90.8-1.7-0.2-1.2
Patch foraging total patch changes 0 sec1.85.48.02.81.8-2.52.7-2.32.8-1.9-2.51.0
Patch foraging total patch changes 12 sec1.11.43.41.41.1-0.50.5-0.21.6-0.0-1.71.9
Patch foraging total patch changes 18 sec1.12.75.42.31.7-0.70.9-0.72.3-0.6-2.31.9
Patch foraging total patch changes 24 sec0.10.52.11.10.7-0.20.3-0.20.5-0.1-1.50.6
Patch foraging total patch changes 6 sec1.01.83.71.40.4-1.51.7-1.41.9-1.0-1.30.6
Patch foraging time to switch 0 sec1.24.47.4-2.7-2.32.1-1.81.9-2.31.72.3-1.5
Patch foraging water rate 0 sec1.14.06.42.52.2-2.02.0-2.12.1-1.7-2.10.8
Patch foraging water rate 12 sec0.72.73.81.81.5-1.71.8-1.81.9-1.8-1.3-0.0
Patch foraging water rate 18 sec0.30.61.61.01.3-0.70.5-0.60.9-0.6-0.80.5
Patch foraging water rate 24 sec1.01.52.60.80.8-1.51.6-1.41.2-1.5-0.2-1.0
Patch foraging water rate 6 sec0.71.01.70.70.7-1.31.3-1.21.3-1.3-0.2-0.3
Seeking ratio, delayed vs. immediate footshock1.31.92.9-1.5-0.81.5-1.51.3-1.71.21.6-0.7
Distance traveled before self-admin0.20.40.9-0.8-1.00.7-1.00.5-0.40.30.6-0.0
Distance traveled after self-admin0.81.33.6-1.5-1.70.0-0.00.0-1.2-0.11.4-1.9
Extensor digitorum longus weight0.41.64.60.40.51.5-1.21.4-0.31.6-0.82.2
Bone: elastic displacement0.81.01.9-1.3-1.10.6-0.80.7-1.00.71.4-1.0
Bone: elastic work1.11.44.4-1.7-1.50.5-0.70.4-0.90.52.1-1.1
Bone: endosteal estimation0.92.25.61.82.00.20.20.01.7-0.1-2.02.4
Bone: endosteal perimeter1.43.46.82.32.6-0.50.9-0.72.5-0.9-2.22.3
Epididymis fat weight0.63.06.7-1.1-1.32.3-2.12.1-1.92.6-0.1-0.1
Delta time in closed arm before/after self-admin1.11.02.2-0.60.01.3-1.31.3-0.21.50.51.2
Delta time in open arm before/after self-admin1.72.03.51.81.5-1.10.9-1.01.9-1.2-1.71.3
Diff in mean of infusions in LGA sessions2.95.27.7-2.7-2.72.0-2.32.1-2.82.02.1-1.5
Delay discount exponential model param0.10.20.5-0.1-0.70.5-0.50.60.30.2-0.30.2
Extinction: sum of active levers before priming0.10.20.50.60.40.1-0.20.2-0.7-0.0-0.70.3
Active lever presses in extinction session 63.33.36.60.60.1-2.62.3-2.60.8-2.3-0.3-2.1
Bone: final force0.00.10.20.1-0.4-0.20.4-0.20.00.3-0.10.3
Bone: final moment0.10.10.30.3-0.3-0.30.4-0.30.40.2-0.30.5
Food consumed during 24 hour testing period1.53.06.81.31.8-2.01.6-2.02.2-2.6-0.60.3
Glucose0.20.30.70.20.50.6-0.70.4-0.80.5-0.4-0.1
Heart weight0.40.61.10.90.3-0.80.9-0.81.0-0.4-0.90.4
Delay discount hyperbolic model param0.20.20.9-0.3-1.00.5-0.50.50.30.2-0.0-0.0
Intermittent access intake day 1-15 change0.42.34.81.10.8-2.22.1-2.00.9-2.1-0.4-0.5
Intermittent access intake escalation0.52.65.31.20.8-2.32.2-2.21.0-2.1-0.5-0.4
Intermittent access intake escalation 20.81.32.50.90.7-1.61.5-1.51.2-1.4-0.4-0.1
Intermitt. access day 1 inactive lever presses0.11.53.9-2.0-1.10.9-0.70.8-1.30.51.8-0.8
Intermitt. access day 15 inactive lever presses0.31.73.4-1.8-1.50.8-0.70.9-1.50.71.8-1.2
Intermitt. access escalation Index0.10.20.6-0.6-0.8-0.00.0-0.00.8-0.30.70.2
Intermittent access day 1 total infusions0.20.71.50.71.2-0.80.9-0.91.1-0.8-0.30.2
Intermittent access day 15 total infusions1.22.95.31.31.6-2.22.3-2.21.3-2.1-0.3-0.3
Intermittent access terminal intake (last 3 days)1.42.54.11.41.8-1.92.0-1.81.8-1.6-0.60.1
Intermittent access total infusions1.11.32.61.21.6-1.11.2-1.11.6-1.0-0.60.5
Intermittent access day 1 locomotion0.20.30.9-0.10.5-0.60.6-0.70.9-0.60.5-0.3
Intermittent access day 15 total locomotion0.52.13.71.01.3-1.91.9-1.91.2-1.7-0.4-0.7
Intermittent access total locomotion0.70.91.60.71.3-1.11.1-1.11.2-0.9-0.3-0.0
Intermittent access standard deviation0.10.41.10.70.80.2-0.10.10.40.1-0.91.1
Left kidney weight0.21.94.41.30.91.5-1.01.3-0.11.3-2.12.1
Right kidney weight0.32.36.11.41.21.4-0.81.20.21.1-2.42.5
Cocaine induced anxiety0.72.03.1-1.5-1.51.7-1.81.6-1.21.51.00.1
Post-drug Anxiety1.21.42.0-1.4-1.21.4-1.41.3-1.01.11.10.1
Baseline Anxiety0.30.40.90.61.0-0.60.8-0.60.6-0.8-0.20.4
Tail length0.84.412.91.81.61.8-1.71.51.21.6-3.03.6
Length with tail0.73.18.01.50.71.5-1.31.50.11.8-2.82.6
Length without tail0.10.72.6-0.5-1.10.4-0.60.6-1.61.0-0.3-0.4
Times rat made contact with spout0.60.71.7-0.2-0.41.1-1.31.00.20.9-0.11.3
Lifetime Intake1.41.72.81.21.7-1.41.6-1.41.7-1.3-0.50.3
Liver weight, left0.50.91.7-0.0-0.00.9-1.01.0-1.21.2-0.81.3
Liver weight, right2.34.17.4-0.4-0.52.6-2.62.4-2.42.7-0.91.7
Locomotor activity0.71.03.21.20.8-0.50.3-0.51.8-0.8-1.40.8
Locomotor testing distance0.71.85.22.01.5-0.30.2-0.41.5-0.3-2.31.5
Locomotor testing rearing0.31.23.71.20.30.7-0.60.80.71.1-1.91.6
Locomotion in novel chamber0.81.12.40.31.0-1.11.5-1.50.5-1.4-0.0-0.7
Locomotion in novel chamber post-restriction1.23.77.11.61.4-2.52.4-2.71.3-2.6-0.7-0.9
Fecal boli incidents, locomotor time 10.41.12.20.91.1-1.51.3-1.40.4-1.40.0-0.4
Change in fecal boli incidents, locomotor task0.60.61.4-1.1-1.20.8-0.70.7-0.80.30.6-0.6
Time >=10cm from walls, locomotor time 11.62.03.40.90.8-1.81.8-1.81.7-1.8-0.4-0.8
Bouts of movement, locomotor time 10.20.20.90.40.6-0.50.1-0.4-0.9-0.5-0.3-0.2
Total resting periods, locomotor time 10.30.31.10.00.2-0.70.3-0.5-1.0-0.60.2-0.7
Rest time, locomotor task time 10.50.82.8-0.7-0.2-0.70.1-0.4-1.7-0.61.0-1.2
Distance moved, locomotor task time 10.30.92.70.81.00.6-0.20.61.10.7-1.11.7
Vertical activity count, locomotor time 10.10.92.21.00.80.60.20.21.50.3-1.21.5
Time >=10cm from walls, locomotor time 20.20.61.41.20.9-0.90.3-0.6-0.1-0.8-1.20.1
Bouts of movement, locomotor time 20.30.92.11.31.4-1.40.4-0.7-0.4-0.7-1.10.4
Total resting periods, locomotor time 20.20.71.61.11.2-1.30.3-0.6-0.6-0.6-0.80.1
Rest time, locomotor task time 20.81.43.7-1.4-1.90.8-1.21.0-1.20.91.2-0.5
Distance moved, locomotor task time 21.21.54.71.72.2-0.60.9-0.80.7-0.8-1.60.9
Vertical activity count, locomotor time 20.41.03.21.41.80.10.3-0.00.7-0.1-1.31.3
Light reinforcement 10.42.04.2-1.2-1.51.6-1.51.6-2.01.60.60.1
Light reinforcement 20.10.20.9-0.0-0.4-0.40.3-0.5-0.9-0.4-0.1-0.5
Bone: marrow area0.82.05.51.71.80.30.10.11.6-0.0-1.92.3
Bone: maximum diameter1.32.65.42.31.7-0.80.8-0.72.1-0.4-2.31.9
Bone: maximum force0.10.20.80.1-0.4-0.40.9-0.50.5-0.00.10.5
Bone: maximum moment0.20.30.70.3-0.2-0.50.9-0.50.8-0.1-0.20.7
Mean time between licks in bursts0.63.68.42.52.9-1.00.8-0.81.3-1.0-2.62.5
Mean num. licks in bursts1.13.04.92.02.1-1.81.3-1.72.2-1.9-1.30.5
Cd content in liver1.01.22.4-0.2-0.41.5-1.51.4-1.11.5-0.40.6
Co content in liver0.70.81.71.21.3-0.2-0.1-0.01.1-0.2-1.11.1
Cu content in liver0.70.91.30.60.91.1-0.81.1-0.70.9-1.11.1
Fe content in liver0.10.10.9-0.20.10.10.10.0-0.90.30.3-0.1
K content in liver0.10.10.4-0.6-0.10.3-0.10.40.30.00.60.3
Mg content in liver0.10.20.40.10.5-0.50.3-0.50.1-0.60.1-0.4
Mn content in liver1.11.23.1-1.4-1.1-0.00.2-0.0-1.2-0.21.8-1.7
Na content in liver1.11.33.50.60.6-1.51.9-1.40.8-1.4-0.2-0.5
Rb content in liver0.20.20.90.30.20.1-0.10.20.90.2-0.20.8
Se content in liver4.45.211.2-3.0-2.51.7-1.31.5-3.41.52.7-1.9
Sr content in liver0.20.20.30.10.1-0.40.5-0.60.4-0.50.0-0.6
Zn content in liver1.41.64.72.02.2-0.30.4-0.20.7-0.4-1.91.2
Bone: minimum diameter1.02.06.81.30.81.2-1.01.01.01.2-1.62.6
Time in familiar zone, hab. session 10.10.10.3-0.50.00.3-0.50.3-0.30.20.30.4
Time in novel zone, hab. session 10.20.20.50.3-0.20.5-0.40.5-0.20.7-0.40.2
Total zone transitions, hab. session 10.50.81.70.2-0.7-1.21.3-1.00.9-0.80.1-0.7
Total locomotion distance, hab. session 11.62.34.8-0.6-1.61.7-1.82.0-1.02.2-0.51.1
Locomotion velocity, hab. session 11.11.63.4-0.4-1.51.4-1.41.7-0.61.8-0.60.9
Time in familiar zone, hab. session 20.80.92.81.11.1-0.3-0.0-0.11.7-0.4-1.01.4
Time in novel zone, hab. session 20.50.62.6-0.5-0.2-0.10.1-0.2-1.60.10.5-1.3
Total zone transitions, hab. session 21.21.53.70.70.1-1.91.9-1.70.5-1.4-0.5-0.8
Total locomotion distance, hab. session 20.81.02.2-0.1-0.90.9-1.01.3-0.81.5-0.81.3
Locomotion velocity, hab. session 20.91.22.6-0.1-0.91.1-1.11.4-0.91.6-0.81.4
Novel to familiar place preference ratio0.20.20.70.2-0.0-0.40.8-0.7-0.4-0.3-0.1-0.4
Novelty place preference0.10.20.40.10.1-0.30.6-0.5-0.6-0.2-0.1-0.5
Time in novel zone, NPP test0.20.20.60.30.3-0.50.8-0.6-0.5-0.4-0.2-0.4
Total zone transitions, NPP test0.40.61.4-0.1-0.0-1.11.2-0.9-0.2-0.80.4-0.9
Total locomotion distance, NPP test1.52.15.9-0.9-1.11.4-1.41.7-2.42.0-0.10.3
Locomotion velocity, NPP test1.92.77.2-1.2-1.51.6-1.71.9-2.72.20.10.2
Intraocular pressure0.61.02.00.41.2-0.91.3-1.20.5-1.40.5-0.9
Delta distance traveled before/after self-admin0.91.02.30.3-0.0-1.51.5-1.20.2-1.20.0-1.2
Delta ambulatory time before/after self-admin0.61.02.30.0-0.0-1.41.5-1.20.2-1.20.1-1.3
Parametrial fat weight0.40.92.8-0.2-1.70.9-0.60.7-0.81.4-0.60.4
Pavlov. Cond. lever latency0.81.02.7-1.1-1.60.7-0.70.5-1.20.80.7-1.2
Pavlov. Cond. magazine entry latency1.92.44.62.12.0-1.11.5-1.11.4-0.9-1.81.5
Pavlov. Cond. change in total contacts0.40.51.70.71.3-0.50.8-0.60.1-0.5-0.50.5
Pavlov. Cond. index score1.41.84.41.72.1-0.71.0-0.61.4-0.7-1.41.6
Pavlov. Cond. latency score1.31.73.81.71.9-0.81.0-0.71.4-0.7-1.41.5
Pavlov. Cond. lever contacts0.60.72.31.01.5-0.30.3-0.10.9-0.5-0.61.3
Pavlov. Cond. magazine entry number1.92.44.9-2.2-2.11.0-1.31.0-1.40.91.8-1.5
Pavlov. Cond. intertrial magazine entries1.72.03.4-1.8-1.21.4-1.71.3-1.81.11.3-1.0
Pavlov. Cond. lever-magazine prob. diff.1.21.53.71.51.9-0.61.0-0.61.4-0.7-1.11.5
Pavlov. Cond. response bias0.70.82.31.21.5-0.30.7-0.30.9-0.4-0.81.3
Pavlov. Cond. lever latency15.121.228.3-5.3-5.24.9-4.95.1-4.44.64.3-1.7
Pavlov. Cond. magazine entry latency3.85.48.42.32.3-2.82.8-2.92.4-2.5-1.40.2
Pavlov. Cond. change in total contacts5.513.419.54.44.2-4.03.8-4.13.1-3.5-3.80.9
Pavlov. Cond. index score9.815.420.24.54.5-4.34.2-4.43.8-3.9-3.51.1
Pavlov. Cond. latency score8.613.918.44.24.1-4.14.1-4.33.6-3.8-3.20.9
Pavlov. Cond. lever contacts13.319.626.55.15.0-4.74.7-4.84.3-4.3-4.31.7
Pavlov. Cond. magazine entry number5.26.812.1-2.8-3.52.9-2.93.0-2.22.71.8-0.0
Pavlov. Cond. intertrial magazine entries0.51.02.90.70.01.0-0.91.00.11.0-1.31.7
Pavlov. Cond. lever-magazine prob. diff.9.214.119.04.44.3-4.03.9-4.23.5-3.7-3.51.1
Pavlov. Cond. response bias14.219.626.95.15.2-4.74.6-4.84.4-4.3-4.11.6
Time in closed arm before self-admin0.40.81.70.30.4-1.21.0-1.30.5-1.30.2-0.8
Time in closed arm after self-admin0.60.73.6-1.3-0.4-0.1-0.2-0.0-0.60.11.9-0.8
Time in open arm before self-admin1.51.92.9-1.2-1.41.4-1.31.6-1.71.70.9-0.7
Time in open arm after self-admin0.60.72.10.90.10.2-0.20.31.20.2-1.41.4
Bone: periosteal estimation0.81.94.81.81.70.3-0.00.11.30.4-2.12.2
Bone: periosteal perimeter1.12.25.21.91.6-0.10.2-0.22.3-0.2-1.92.2
Bone: post-yield work0.40.83.10.7-0.4-0.40.9-0.51.7-0.3-0.61.2
Progressive ratio test 1 active lever presses0.20.30.8-0.5-0.1-0.50.5-0.40.2-0.30.9-0.9
Progressive ratio test 1 breakpoint0.20.30.7-0.5-0.1-0.50.5-0.40.3-0.30.8-0.8
Progressive ratio test 1 inactive lever presses0.10.41.4-1.0-0.8-0.10.1-0.10.2-0.11.2-0.6
Progressive ratio test 2 active lever presses0.60.83.31.01.8-0.60.7-0.60.9-0.5-0.70.2
Progressive ratio test 2 breakpoint0.60.83.41.01.8-0.70.7-0.60.9-0.6-0.70.2
Progressive ratio test 2 inactive lever presses0.10.31.10.51.1-0.40.5-0.30.6-0.3-0.2-0.0
Incentive Sensitization - Responses0.61.65.21.62.3-0.80.9-0.81.3-0.9-1.40.7
Incentive Sensitization - Breakpoint0.61.54.91.52.2-0.80.9-0.71.2-0.9-1.30.7
Sum of active levers in priming session hrs 5-60.30.30.70.40.0-0.50.3-0.4-0.8-0.4-0.8-0.4
Progressive ratio0.10.40.80.10.5-0.90.9-0.70.3-0.70.4-0.4
Food seeking constrained by brief footshock1.72.15.82.01.2-1.01.0-1.31.2-0.9-2.41.2
Seeking ratio, punishment vs. effort0.51.04.31.40.60.2-0.1-0.10.70.2-2.11.6
Retroperitoneal fat weight2.913.030.8-0.8-2.04.8-4.54.7-2.55.5-1.42.8
Reaction time number correct0.20.81.5-0.6-0.8-1.21.1-1.00.2-0.90.6-1.1
Reaction time mean minus median0.21.43.41.81.2-0.50.3-0.81.2-0.5-1.81.2
Reaction time mean minus median AUC0.21.42.91.71.0-1.00.9-1.21.3-0.9-1.60.7
Reaction time num false alarms1.83.14.8-2.0-1.62.1-2.22.2-1.62.01.00.3
Reaction time num false alarms AUC0.81.82.9-1.7-1.01.5-1.61.6-1.41.31.10.0
Reaction time trials correct on left0.20.81.5-0.6-0.8-1.21.1-1.00.2-0.90.6-1.1
Reaction time trials on left0.20.81.6-0.5-0.8-1.31.1-1.00.2-1.00.6-1.2
Reaction time mean0.10.30.70.2-0.20.7-0.80.3-0.30.6-0.60.6
Reaction time mean AUC0.10.30.8-0.2-0.40.8-0.90.4-0.80.7-0.10.3
Median of all reaction times0.20.40.9-0.5-0.60.8-0.90.4-0.70.70.00.3
Reaction time omissions0.20.30.90.70.70.1-0.4-0.2-0.60.2-0.90.4
Reaction time false alarm rate1.62.34.0-1.4-0.82.0-2.01.9-1.51.70.80.4
Reaction time premature initiation rate1.42.17.31.81.20.4-0.30.41.20.7-2.22.7
Reaction time premature initiations0.41.23.11.40.9-0.40.5-0.31.30.0-1.71.8
Std. dev. reaction times0.31.02.81.41.00.3-0.5-0.00.70.3-1.71.5
Reaction time trials completed0.20.81.6-0.5-0.8-1.31.1-1.00.2-1.00.6-1.2
Reaction time trials AUC0.20.71.5-0.4-0.7-1.21.1-1.00.2-0.80.3-1.0
Run reversals in cocaine runway, females2.02.25.70.10.32.0-1.71.90.11.8-0.72.4
Run reversals in cocaine runway, males0.20.31.40.40.3-1.20.3-0.50.2-0.30.60.1
Latency to leave start box in cocaine runway1.52.03.0-1.7-1.71.3-1.51.4-1.71.31.2-0.4
Latency to leave start box in cocaine runway, F1.92.33.5-1.5-1.41.8-1.81.9-1.81.70.80.2
Latency to leave start box in cocaine runway, M0.40.40.8-0.8-0.6-0.4-0.1-0.2-0.5-0.10.9-0.9
Std. dev. time between licks in bursts0.61.13.71.00.90.30.10.30.80.1-1.81.9
Total sessions with >9 infusions1.41.72.91.01.3-1.71.6-1.51.7-1.4-0.40.3
Short access day 1 total inactive lever presses0.10.30.70.20.8-0.50.8-0.50.2-0.70.1-0.1
Short access day 10 total inactive lever presses0.21.23.1-1.4-1.81.0-0.80.9-0.90.81.1-0.7
Short access day 1 total infusions1.42.84.11.81.9-1.81.8-1.62.0-1.5-1.41.0
Short access day 10 total infusions0.50.91.80.71.4-1.01.2-0.91.3-0.7-0.30.4
Short access total infusions1.42.03.31.11.8-1.71.8-1.51.7-1.5-0.40.3
Short access day 1 locomotion2.03.45.81.21.5-2.42.4-2.32.2-2.1-0.4-0.4
Short access day 10 total locomotion0.31.22.91.01.7-1.31.0-1.20.9-1.1-0.70.2
Short access total locomotion0.81.32.30.21.0-1.51.4-1.41.5-1.30.1-0.3
One hour access (0.3 mA shock)0.70.92.11.01.5-0.80.8-0.81.2-0.7-0.80.1
Compulsive drug intake0.50.72.7-0.8-1.0-0.10.0-0.1-1.0-0.20.8-1.6
One hour access (shock baseline)0.71.83.81.31.9-1.41.5-1.41.5-1.3-0.70.4
Social response proportion0.60.81.3-0.8-1.10.7-1.10.9-1.11.10.10.4
Social responses1.21.63.1-0.8-0.91.5-1.81.7-1.01.7-0.11.0
Social time2.33.79.6-2.4-1.91.2-1.71.3-3.11.52.0-1.4
Soleus weight0.92.68.30.3-0.02.0-1.72.0-0.02.0-1.02.9
Bone: stiffness0.20.41.5-0.5-1.20.20.40.2-0.50.70.40.5
Tibialis anterior weight0.10.52.10.80.30.3-0.10.10.40.3-1.11.4
Time to tail flick, vehicle, before self-admin0.20.20.80.10.20.4-0.30.50.40.4-0.00.9
Time to tail flick, vehicle, after self-admin0.51.12.21.21.2-1.01.1-1.01.5-1.0-0.70.5
Time to tail flick, test, before self-admin0.60.72.20.70.40.4-0.50.60.90.8-0.91.5
Time to tail flick, test, after self-admin0.40.51.00.61.00.5-0.50.50.10.5-0.91.0
Delta time to tail flick, vehicle, before/after SA1.31.42.30.90.9-1.51.5-1.51.1-1.3-0.4-0.6
Delta time to tail flick, test, before/after SA0.20.30.7-0.7-0.50.2-0.00.0-0.8-0.10.5-0.8
Tibia length1.13.15.51.80.8-2.32.3-2.11.6-1.9-1.3-1.0
Ambulatory time before self-admin0.20.61.4-1.1-1.00.4-0.70.2-0.80.11.2-0.9
Ambulatory time after self-admin0.91.45.4-1.3-1.2-0.50.6-0.5-1.1-0.61.3-2.3
Bone: tissue strength0.91.03.4-0.8-1.8-0.61.0-0.4-0.1-0.21.0-1.5
Total heroin consumption0.00.10.30.1-0.3-0.10.00.2-0.50.1-0.2-0.1
Bone: trabecular number0.61.12.4-1.3-1.51.1-0.70.90.11.01.50.0
Bone: trabecular spacing1.11.62.41.31.1-1.61.5-1.40.6-1.5-1.0-0.8
Bone: trabecular thickness0.70.91.8-0.4-0.61.4-1.21.1-0.21.3-0.11.1
Bone: trabecular tissue density0.91.52.6-0.9-1.61.2-1.31.5-1.61.6-0.20.5
Water consumed over 24 hours0.40.81.6-1.3-0.90.9-1.00.9-0.50.71.10.0
Number of responses in last shaping day1.62.14.2-1.0-1.11.9-1.82.0-0.51.90.31.3