Hub : Genes

Lrrc32

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA NM_001170434.2 0.02 0.02 5.4e-03 0.01 0.02 0.01 0.01 7.7e-03 5.6e-03 1.5e-02 1.7e-02
2 Liver gene expression Lrrc32 0.11 0.1 1.4e-04 0.04 0.03 0.03 0.03 7.2e-05 4.5e-04 1.3e-04 4.3e-04
3 PL alternative polyA XM_006229747.4 0.02 0.02 6.8e-03 0.02 0.01 0.01 0.01 5.1e-03 7.3e-03 2.0e-02 1.8e-02
4 Adipose gene expression Lrrc32 0.05 0.04 4.9e-04 0.03 0.01 0.01 0.01 3.7e-04 8.6e-03 7.6e-03 8.3e-03
5 PL gene expression Lrrc32 0.03 0.02 1.8e-03 0.02 0.01 0.01 0.01 6.1e-03 3.1e-02 9.6e-03 2.5e-02
6 Adipose alternative TSS XM_039106013.1 0.04 0.03 4.0e-03 0.01 0 0 0 1.5e-02 7.3e-02 1.4e-01 1.3e-01
7 Adipose alternative TSS XM_039106013.1 0.04 0.04 2.0e-03 0.01 0.01 0 0 5.1e-02 4.2e-02 9.8e-02 8.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.20.50.30.10.30.3-0.70.6-0.2
Area under the delay curve0.20.20.7-0.3-0.4-0.9-0.40.4-0.10.2
BMI with tail0.51.62.61.21.61.31.5-1.50.4-1.2
BMI without tail3.77.612.81.82.62.62.7-2.62.9-3.6
Body weight1.25.110.11.52.11.92.0-2.02.7-3.2
Weight adjusted by age0.91.03.10.30.70.50.8-0.61.5-1.8
Bone surface0.61.12.9-1.1-1.0-0.6-0.80.31.7-1.3
Bone volume0.40.62.3-0.4-0.20.0-0.1-0.41.5-1.3
Breakpoint value in progressive ratio session0.10.20.50.20.20.20.1-0.2-0.70.7
Number of licking bursts3.03.56.22.52.12.02.2-2.2-0.20.3
Context. condit. distance diff. score1.41.73.4-1.8-1.4-1.5-1.41.5-0.2-0.0
Locomotion velocity, session 10.70.82.2-0.3-0.7-0.5-0.60.6-1.51.4
Locomotion distance, session 11.11.52.0-1.2-1.2-1.3-1.31.4-1.20.9
Locomotion velocity, session 20.10.10.2-0.3-0.4-0.3-0.40.4-0.20.1
Locomotion distance, session 20.20.30.4-0.6-0.6-0.6-0.60.4-0.40.2
Locomotion velocity, session 30.30.30.8-0.7-0.5-0.4-0.60.4-0.90.4
Locomotion distance, session 31.11.21.5-1.2-1.2-1.1-1.21.0-1.10.9
Stereotopy head waving bouts, day 30.50.61.10.80.81.00.7-0.80.6-0.3
Stereotopy head waving duration, day 30.30.30.7-0.6-0.6-0.6-0.70.80.00.1
Locomotion velocity, session 70.20.20.50.40.40.60.4-0.5-0.70.3
Locomotion distance, session 70.10.10.20.40.50.40.4-0.40.0-0.4
Stereotopy head waving bouts, day 71.41.52.4-1.6-1.5-1.3-1.51.4-0.40.5
Stereotopy head waving duration, day 71.51.83.0-1.7-1.6-1.4-1.61.50.2-0.1
Locomotion velocity, session 81.41.72.6-1.6-1.5-1.5-1.61.50.5-0.1
Locomotion distance, session 81.11.73.1-1.8-1.4-1.4-1.51.4-0.30.1
Degree of sensitization distance1.81.83.01.21.31.11.2-1.11.7-1.7
Degree of sensitization stereotypy3.84.26.2-2.5-2.4-2.3-2.42.3-0.50.7
Conditioned locomotion0.20.20.3-0.2-0.3-0.4-0.30.5-0.60.6
Cocaine response after cond. corrected0.70.81.71.31.00.91.1-1.0-0.10.1
Cocaine response after cond. not corrected0.10.10.30.50.1-0.00.1-0.1-0.40.5
Cocaine response before conditioning1.61.92.8-1.5-1.6-1.5-1.71.6-0.40.8
Saline control response0.91.21.3-1.1-1.0-0.9-1.11.11.2-1.1
Bone: connectivity density0.20.30.6-0.6-0.8-0.4-0.60.20.50.2
Bone: cortical apparent density0.91.11.91.41.21.31.1-1.10.6-0.3
Bone: cortical area0.40.62.3-0.20.10.10.3-0.41.4-1.5
Bone: cortical porosity1.61.72.4-1.5-1.4-1.5-1.61.3-0.90.8
Bone: cortical porosity1.31.42.0-1.2-1.2-1.2-1.41.1-1.00.9
Bone: cortical thickness0.20.40.80.60.70.60.8-0.9-0.0-0.2
Bone: cortical thickness0.10.20.3-0.4-0.3-0.5-0.40.3-0.50.2
Bone: cortical tissue density0.81.11.81.31.21.31.1-1.00.5-0.2
Condit. Reinf. active minus inactive responses0.91.02.00.61.00.90.9-1.01.2-1.4
Condit. Reinf. active-inactive response ratio0.91.03.10.10.50.50.4-0.61.8-1.7
Condit. Reinf. active responses0.70.81.10.81.10.91.0-1.00.6-0.8
Condit. Reinf. inactive responses0.20.20.40.50.50.40.5-0.4-0.70.4
Incentive salience index mean0.70.91.50.50.90.90.8-1.01.0-1.2
Condit. Reinf. lever presses0.10.10.20.20.40.40.3-0.30.3-0.4
Condit. Reinf. active minus inactive responses2.73.35.3-2.3-1.7-1.9-1.61.81.5-1.7
Condit. Reinf. active-inactive response ratio0.30.30.7-0.8-0.5-0.6-0.50.60.0-0.5
Condit. Reinf. active responses3.85.37.5-2.7-2.1-2.2-2.01.92.5-2.6
Condit. Reinf. inactive responses2.73.46.6-1.9-1.5-1.4-1.51.32.6-2.3
Condit. Reinf. lever presses12.516.927.0-5.2-4.6-4.5-4.64.52.2-1.9
Condit. Reinf. lever reinforcers received4.36.19.2-3.0-2.3-2.5-2.32.32.3-2.5
Conditioned reinforcement - actives2.92.94.6-1.9-1.9-2.2-1.91.9-0.70.7
Conditioned reinforcement - inactives0.10.10.30.30.0-0.60.00.1-0.20.4
Conditioned locomotion2.63.14.4-1.9-1.9-2.1-1.92.0-1.10.8
Patch foraging indifference point 0 sec3.55.78.8-3.0-2.5-2.6-2.72.91.2-1.2
Patch foraging indifference point AUC0.20.31.10.10.30.20.3-0.21.0-0.8
Delay disc. indifference point, 0s delay0.30.30.7-0.7-0.6-0.8-0.60.60.1-0.3
Delay disc. indifference point, 16s delay0.30.30.6-0.3-0.6-0.5-0.60.3-0.60.8
Delay disc. indifference point, 2s delay1.21.32.6-1.3-1.2-1.6-1.21.30.0-0.0
Delay disc. indifference point, 24s delay0.40.40.80.90.70.60.7-0.80.10.2
Delay disc. indifference point, 4s delay0.10.10.2-0.4-0.4-0.2-0.40.30.2-0.5
Delay disc. indifference point, 8s delay0.50.61.9-0.7-0.7-1.4-0.70.70.10.1
Indifference point function ln k2.02.94.0-1.8-1.9-1.9-1.92.0-1.10.9
Indifference point function log k2.02.94.0-1.8-1.9-1.9-1.92.0-1.10.9
Patch foraging total patch changes 0 sec3.04.87.4-2.7-2.3-2.4-2.52.71.1-1.0
Patch foraging total patch changes 12 sec0.81.03.2-0.7-0.2-0.5-0.30.61.8-1.7
Patch foraging total patch changes 18 sec0.91.12.7-1.1-0.6-0.6-0.60.81.6-1.6
Patch foraging total patch changes 24 sec0.20.20.7-0.4-0.2-0.3-0.20.20.5-0.8
Patch foraging total patch changes 6 sec1.11.62.9-1.5-1.2-1.5-1.41.70.4-0.3
Patch foraging time to switch 0 sec2.33.65.52.31.92.02.1-1.9-1.61.4
Patch foraging water rate 0 sec2.13.45.6-2.4-2.1-2.1-2.11.90.8-0.8
Patch foraging water rate 12 sec1.72.64.1-2.0-1.9-2.0-1.91.80.1-0.2
Patch foraging water rate 18 sec0.30.40.7-0.8-0.7-0.6-0.70.50.6-0.7
Patch foraging water rate 24 sec1.21.72.3-1.5-1.4-1.4-1.41.4-1.00.7
Patch foraging water rate 6 sec0.91.32.2-1.4-1.3-1.5-1.21.2-0.30.4
Seeking ratio, delayed vs. immediate footshock1.21.32.11.51.21.21.4-1.3-0.60.6
Distance traveled before self-admin0.30.30.80.60.40.80.5-0.90.00.1
Distance traveled after self-admin0.70.72.50.50.10.20.2-0.2-1.61.5
Extensor digitorum longus weight0.62.43.91.11.21.41.6-1.42.0-1.8
Bone: elastic displacement0.70.81.31.00.70.80.9-1.2-0.90.8
Bone: elastic work0.70.92.10.90.30.70.6-1.0-1.31.4
Bone: endosteal estimation0.71.44.9-0.6-0.10.1-0.0-0.12.2-2.2
Bone: endosteal perimeter0.91.84.4-1.3-0.8-0.7-0.90.62.1-2.0
Epididymis fat weight2.45.77.12.22.62.62.7-2.61.5-2.2
Delta time in closed arm before/after self-admin2.22.12.81.31.41.61.4-1.41.7-1.5
Delta time in open arm before/after self-admin1.31.21.7-1.3-1.1-1.2-1.11.01.1-1.0
Diff in mean of infusions in LGA sessions3.13.45.02.12.12.22.0-2.2-0.60.4
Delay discount exponential model param0.20.20.60.30.50.80.5-0.40.2-0.3
Extinction: sum of active levers before priming0.30.30.90.50.50.90.5-0.70.2-0.3
Active lever presses in extinction session 64.64.56.7-2.5-2.5-2.2-2.62.1-1.41.2
Bone: final force0.10.10.3-0.3-0.3-0.3-0.30.10.6-0.2
Bone: final moment0.10.20.6-0.4-0.4-0.3-0.40.10.8-0.4
Food consumed during 24 hour testing period2.32.84.5-2.1-2.0-1.7-2.11.90.20.3
Glucose0.10.10.2-0.3-0.3-0.2-0.40.3-0.50.2
Heart weight0.71.01.4-1.2-1.1-1.1-1.21.10.6-0.4
Delay discount hyperbolic model param0.20.30.70.40.60.90.6-0.50.0-0.1
Intermittent access intake day 1-15 change3.03.05.1-1.9-1.9-2.3-1.92.0-0.50.6
Intermittent access intake escalation3.63.56.3-2.1-2.1-2.5-2.12.2-0.50.6
Intermittent access intake escalation 20.80.81.8-1.0-0.9-1.4-0.90.90.1-0.1
Intermitt. access day 1 inactive lever presses0.20.30.70.80.60.40.6-0.4-0.10.2
Intermitt. access day 15 inactive lever presses0.20.20.4-0.1-0.1-0.6-0.10.4-0.60.6
Intermitt. access escalation Index0.00.00.2-0.1-0.10.1-0.10.10.4-0.1
Intermittent access day 1 total infusions0.30.40.7-0.6-0.5-0.5-0.50.50.8-0.7
Intermittent access day 15 total infusions2.73.05.0-2.0-2.0-2.2-2.02.1-0.10.2
Intermittent access terminal intake (last 3 days)1.41.53.2-1.4-1.2-1.8-1.21.40.3-0.2
Intermittent access total infusions0.50.50.9-0.8-0.7-0.9-0.70.90.3-0.4
Intermittent access day 1 locomotion0.10.10.2-0.2-0.3-0.4-0.30.3-0.30.4
Intermittent access day 15 total locomotion1.51.62.8-1.5-1.4-1.7-1.41.4-0.40.1
Intermittent access total locomotion0.30.41.0-0.7-0.6-1.0-0.60.70.1-0.3
Intermittent access standard deviation0.00.00.1-0.1-0.1-0.0-0.10.10.3-0.4
Left kidney weight0.61.86.5-0.20.30.40.4-0.32.3-2.5
Right kidney weight0.51.34.3-0.10.30.40.3-0.42.1-2.1
Cocaine induced anxiety1.61.92.91.61.51.71.5-1.7-0.50.6
Post-drug Anxiety0.30.30.60.70.50.70.5-0.7-0.00.3
Baseline Anxiety2.32.43.8-1.7-1.7-1.9-1.71.90.6-0.4
Tail length2.47.422.40.41.11.51.3-1.34.7-4.7
Length with tail1.34.612.60.81.31.31.3-1.33.5-3.5
Length without tail0.20.31.20.20.0-0.4-0.10.2-1.11.0
Times rat made contact with spout1.11.31.81.01.01.31.0-1.31.2-0.9
Lifetime Intake0.70.81.3-1.0-1.0-1.0-1.01.10.3-0.3
Liver weight, left0.81.32.61.20.90.90.9-0.91.6-1.2
Liver weight, right3.25.36.32.52.52.42.5-2.41.9-1.8
Locomotor activity0.30.50.9-0.9-0.5-0.5-0.70.70.8-0.8
Locomotor testing distance0.71.23.0-1.3-0.7-0.8-0.70.81.4-1.7
Locomotor testing rearing0.81.24.30.10.60.40.5-0.41.7-2.1
Locomotion in novel chamber1.41.72.7-1.5-1.6-1.5-1.61.3-0.60.5
Locomotion in novel chamber post-restriction4.85.88.6-2.7-2.8-2.8-2.92.5-1.10.9
Fecal boli incidents, locomotor time 11.31.42.5-1.3-1.4-1.4-1.21.6-0.40.4
Change in fecal boli incidents, locomotor task0.60.60.91.00.80.80.5-0.9-0.70.7
Time >=10cm from walls, locomotor time 12.32.33.7-1.8-1.9-1.7-1.81.7-0.70.6
Bouts of movement, locomotor time 10.10.10.3-0.4-0.5-0.2-0.50.1-0.30.2
Total resting periods, locomotor time 10.30.30.6-0.3-0.6-0.3-0.50.2-0.80.7
Rest time, locomotor task time 10.50.61.7-0.0-0.5-0.3-0.60.0-1.31.3
Distance moved, locomotor task time 11.01.03.30.10.60.30.8-0.21.7-1.8
Vertical activity count, locomotor time 10.70.72.3-0.40.3-0.30.40.21.5-1.5
Time >=10cm from walls, locomotor time 20.40.40.8-0.9-0.8-0.6-0.80.40.1-0.3
Bouts of movement, locomotor time 20.20.30.5-0.6-0.7-0.2-0.70.30.4-0.4
Total resting periods, locomotor time 20.10.10.3-0.5-0.6-0.1-0.60.20.1-0.1
Rest time, locomotor task time 20.91.01.91.40.90.91.1-1.1-0.50.9
Distance moved, locomotor task time 20.91.12.0-1.3-0.8-0.8-0.81.11.0-1.4
Vertical activity count, locomotor time 20.80.83.2-0.60.2-0.10.10.21.5-1.8
Light reinforcement 11.12.13.61.91.71.51.8-1.7-0.00.2
Light reinforcement 20.20.30.6-0.3-0.5-0.6-0.50.4-0.50.8
Bone: marrow area0.61.44.8-0.4-0.00.20.0-0.22.2-2.1
Bone: maximum diameter0.91.73.5-1.4-1.0-1.0-0.80.81.8-1.9
Bone: maximum force0.20.30.6-0.6-0.6-0.5-0.60.30.8-0.2
Bone: maximum moment0.20.40.9-0.7-0.7-0.5-0.70.31.0-0.4
Mean time between licks in bursts1.82.66.8-1.5-0.9-0.8-0.90.82.6-2.5
Mean num. licks in bursts1.92.34.3-2.1-1.7-1.5-1.81.50.7-0.7
Cd content in liver1.61.82.41.41.41.51.6-1.50.9-0.7
Co content in liver0.70.82.4-0.00.30.50.3-0.51.5-1.6
Cu content in liver0.30.41.5-0.10.40.2-0.10.31.1-1.2
Fe content in liver0.00.00.10.10.10.20.1-0.10.1-0.2
K content in liver0.30.30.50.60.70.70.6-0.40.4-0.2
Mg content in liver0.10.10.2-0.4-0.3-0.2-0.30.30.1-0.2
Mn content in liver0.80.92.80.60.40.20.2-0.5-1.61.7
Na content in liver1.51.62.4-1.2-1.3-1.5-1.51.6-0.70.9
Rb content in liver0.30.41.3-0.5-0.1-0.2-0.40.41.0-1.1
Se content in liver2.02.53.82.01.51.51.4-1.6-1.41.6
Sr content in liver0.20.10.6-0.2-0.2-0.2-0.20.2-0.80.5
Zn content in liver2.32.64.7-2.2-1.6-1.6-1.71.90.8-1.0
Bone: minimum diameter1.32.56.10.60.91.11.2-1.32.5-2.4
Time in familiar zone, hab. session 10.10.10.30.40.30.20.30.00.5-0.1
Time in novel zone, hab. session 10.30.30.50.40.50.50.6-0.70.1-0.5
Total zone transitions, hab. session 10.81.21.7-0.9-1.1-1.3-1.01.3-0.81.0
Total locomotion distance, hab. session 12.02.84.21.82.01.82.0-1.61.0-1.0
Locomotion velocity, hab. session 11.31.92.91.51.71.51.6-1.40.8-0.9
Time in familiar zone, hab. session 20.60.62.0-0.6-0.1-0.1-0.10.41.4-1.2
Time in novel zone, hab. session 20.40.41.90.1-0.2-0.2-0.2-0.1-1.40.9
Total zone transitions, hab. session 22.02.63.8-1.7-1.7-2.0-1.81.8-0.81.0
Total locomotion distance, hab. session 21.01.31.71.01.31.11.3-0.91.2-1.0
Locomotion velocity, hab. session 21.11.52.01.21.41.21.4-1.11.3-1.1
Novel to familiar place preference ratio0.30.30.5-0.5-0.7-0.6-0.70.6-0.40.4
Novelty place preference0.20.20.3-0.4-0.5-0.4-0.50.4-0.50.4
Time in novel zone, NPP test0.30.30.5-0.5-0.6-0.5-0.70.5-0.50.3
Total zone transitions, NPP test0.71.01.2-0.8-1.0-1.1-1.01.0-0.91.1
Total locomotion distance, NPP test1.52.03.21.61.71.61.8-1.60.3-0.4
Locomotion velocity, NPP test1.82.54.01.91.91.82.0-1.80.2-0.3
Intraocular pressure0.81.11.5-1.2-1.1-1.1-1.11.1-0.80.6
Delta distance traveled before/after self-admin0.60.60.8-0.5-0.6-0.9-0.70.9-0.90.9
Delta ambulatory time before/after self-admin1.11.21.9-0.7-0.8-1.1-0.91.2-1.41.3
Parametrial fat weight0.81.62.11.31.21.31.1-1.31.4-1.2
Pavlov. Cond. lever latency0.40.51.10.80.50.50.7-0.5-1.10.8
Pavlov. Cond. magazine entry latency1.01.31.9-1.3-1.0-1.0-1.00.91.4-1.3
Pavlov. Cond. change in total contacts0.30.30.5-0.7-0.5-0.5-0.70.40.5-0.5
Pavlov. Cond. index score0.91.12.6-1.1-0.6-0.5-0.70.61.6-1.5
Pavlov. Cond. latency score0.91.12.3-1.1-0.7-0.6-0.80.71.5-1.4
Pavlov. Cond. lever contacts0.40.41.6-0.30.00.1-0.2-0.01.3-1.1
Pavlov. Cond. magazine entry number1.21.52.31.51.11.01.2-1.1-1.21.3
Pavlov. Cond. intertrial magazine entries1.31.62.31.51.31.31.3-1.5-1.10.7
Pavlov. Cond. lever-magazine prob. diff.0.70.92.3-0.9-0.5-0.5-0.70.51.5-1.4
Pavlov. Cond. response bias0.30.41.5-0.3-0.00.1-0.1-0.11.2-1.1
Pavlov. Cond. lever latency12.817.328.55.34.94.64.7-4.5-1.81.5
Pavlov. Cond. magazine entry latency4.65.38.6-2.9-2.8-2.7-2.62.50.2-0.1
Pavlov. Cond. change in total contacts8.912.320.7-4.6-4.1-4.0-3.93.90.8-1.0
Pavlov. Cond. index score10.313.222.4-4.7-4.3-4.1-4.14.01.2-1.1
Pavlov. Cond. latency score10.012.420.7-4.6-4.2-4.0-4.03.90.9-0.9
Pavlov. Cond. lever contacts13.418.330.2-5.5-4.9-4.7-4.84.71.8-1.7
Pavlov. Cond. magazine entry number5.36.511.53.43.02.92.9-2.8-0.00.3
Pavlov. Cond. intertrial magazine entries1.31.72.80.91.21.21.1-1.11.7-1.7
Pavlov. Cond. lever-magazine prob. diff.9.512.120.5-4.5-4.1-3.9-3.93.81.1-1.1
Pavlov. Cond. response bias13.218.030.3-5.5-4.9-4.7-4.74.61.7-1.6
Time in closed arm before self-admin2.42.73.7-1.6-1.8-1.9-1.81.7-1.31.3
Time in closed arm after self-admin0.40.41.60.0-0.4-0.5-0.40.3-1.01.2
Time in open arm before self-admin2.42.64.02.02.01.91.8-1.7-0.50.3
Time in open arm after self-admin0.80.92.50.20.60.60.6-0.61.6-1.6
Bone: periosteal estimation0.71.44.9-0.6-0.2-0.1-0.0-0.22.1-2.2
Bone: periosteal perimeter0.81.33.9-1.0-0.5-0.4-0.50.32.0-1.9
Bone: post-yield work0.40.60.9-0.8-0.8-0.5-0.90.81.0-0.3
Progressive ratio test 1 active lever presses0.10.10.30.30.1-0.00.1-0.1-0.50.5
Progressive ratio test 1 breakpoint0.10.10.20.30.20.10.2-0.1-0.30.4
Progressive ratio test 1 inactive lever presses0.00.00.1-0.2-0.1-0.2-0.10.20.3-0.2
Progressive ratio test 2 active lever presses0.60.71.1-1.0-0.7-0.9-0.70.80.5-0.9
Progressive ratio test 2 breakpoint0.50.60.9-1.0-0.6-0.9-0.60.80.6-0.9
Progressive ratio test 2 inactive lever presses0.30.40.8-0.7-0.5-0.9-0.50.70.3-0.5
Incentive Sensitization - Responses1.21.21.9-1.4-0.9-1.0-0.91.11.0-1.3
Incentive Sensitization - Breakpoint1.21.32.1-1.4-1.0-1.1-1.01.20.8-1.1
Sum of active levers in priming session hrs 5-60.00.00.10.10.10.30.0-0.1-0.20.1
Progressive ratio0.30.30.4-0.5-0.5-0.6-0.60.6-0.60.6
Food seeking constrained by brief footshock0.91.01.3-1.1-1.1-0.7-1.10.91.1-1.1
Seeking ratio, punishment vs. effort0.60.72.3-0.3-0.30.0-0.10.21.5-1.5
Retroperitoneal fat weight7.323.831.05.05.65.35.3-5.53.2-3.7
Reaction time number correct0.81.12.1-0.8-1.1-1.0-0.90.8-1.21.4
Reaction time mean minus median0.50.71.5-0.9-0.6-0.5-0.80.41.1-1.2
Reaction time mean minus median AUC0.91.11.7-1.3-1.1-1.1-1.21.10.7-0.7
Reaction time num false alarms2.53.45.42.12.22.12.3-2.10.2-0.2
Reaction time num false alarms AUC1.41.92.91.61.61.61.7-1.6-0.20.2
Reaction time trials correct on left0.81.12.1-0.8-1.1-1.0-0.90.8-1.21.4
Reaction time trials on left0.81.22.1-0.8-1.1-1.0-1.00.9-1.21.5
Reaction time mean0.20.30.40.60.40.60.3-0.50.7-0.6
Reaction time mean AUC0.20.30.60.80.50.70.4-0.60.3-0.2
Median of all reaction times0.20.30.80.90.50.70.4-0.60.3-0.1
Reaction time omissions0.00.10.10.2-0.00.10.2-0.40.2-0.3
Reaction time false alarm rate1.92.74.01.92.01.92.0-1.90.3-0.4
Reaction time premature initiation rate1.62.27.6-0.20.50.20.4-0.22.7-2.8
Reaction time premature initiations0.71.02.9-0.7-0.3-0.5-0.30.41.7-1.7
Std. dev. reaction times0.50.72.8-0.10.10.40.1-0.31.5-1.7
Reaction time trials completed0.81.22.1-0.8-1.1-1.0-1.00.9-1.21.5
Reaction time trials AUC0.70.91.5-0.8-1.1-0.9-0.90.8-1.01.2
Run reversals in cocaine runway, females4.64.47.41.72.11.72.1-1.62.7-2.6
Run reversals in cocaine runway, males0.10.10.3-0.3-0.50.1-0.50.40.10.3
Latency to leave start box in cocaine runway1.31.42.51.41.11.61.1-1.5-0.50.6
Latency to leave start box in cocaine runway, F1.41.52.71.41.31.51.3-1.60.00.0
Latency to leave start box in cocaine runway, M0.30.31.10.1-0.2-0.0-0.20.2-0.81.0
Std. dev. time between licks in bursts0.81.03.5-0.10.30.30.3-0.21.9-1.8
Total sessions with >9 infusions1.92.13.4-1.8-1.6-1.7-1.61.8-0.10.0
Short access day 1 total inactive lever presses0.10.10.30.2-0.1-0.3-0.10.5-0.30.2
Short access day 10 total inactive lever presses0.10.10.10.30.20.10.20.0-0.40.4
Short access day 1 total infusions1.61.72.6-1.6-1.5-1.3-1.51.60.7-0.6
Short access day 10 total infusions0.20.30.4-0.5-0.3-0.3-0.30.60.6-0.7
Short access total infusions0.30.40.7-0.7-0.6-0.5-0.60.90.6-0.5
Short access day 1 locomotion3.84.15.6-2.2-2.3-2.3-2.32.4-1.21.1
Short access day 10 total locomotion0.10.10.2-0.5-0.3-0.3-0.30.20.0-0.3
Short access total locomotion0.30.30.6-0.5-0.5-0.8-0.50.6-0.30.4
One hour access (0.3 mA shock)0.80.91.8-1.3-1.0-1.0-1.00.90.4-0.8
Compulsive drug intake0.20.20.8-0.3-0.1-0.0-0.10.1-0.90.4
One hour access (shock baseline)1.11.22.5-1.2-1.2-1.6-1.21.20.6-0.5
Social response proportion0.50.61.01.00.90.90.7-0.90.4-0.1
Social responses1.72.22.91.51.61.61.6-1.71.1-1.0
Social time1.52.02.91.71.41.21.2-1.4-1.51.4
Soleus weight1.54.47.61.61.91.91.8-1.92.8-2.4
Bone: stiffness0.10.10.80.10.0-0.1-0.10.10.9-0.2
Tibialis anterior weight0.10.41.7-0.0-0.00.10.2-0.31.3-1.1
Time to tail flick, vehicle, before self-admin0.80.91.20.91.11.01.1-1.00.8-0.5
Time to tail flick, vehicle, after self-admin1.81.93.1-1.7-1.6-1.8-1.61.6-0.00.1
Time to tail flick, test, before self-admin0.20.20.70.10.4-0.00.2-0.30.8-0.8
Time to tail flick, test, after self-admin0.30.31.10.00.1-0.00.1-0.20.9-1.0
Delta time to tail flick, vehicle, before/after SA4.54.46.3-2.3-2.4-2.5-2.42.4-1.10.8
Delta time to tail flick, test, before/after SA0.10.10.40.1-0.2-0.0-0.10.2-0.60.5
Tibia length1.43.96.1-2.4-2.1-2.5-2.12.3-1.00.7
Ambulatory time before self-admin0.30.30.50.50.20.50.4-0.7-0.60.6
Ambulatory time after self-admin1.11.24.30.2-0.2-0.4-0.20.3-2.11.9
Bone: tissue strength1.11.12.8-0.4-0.6-0.7-0.70.8-1.61.7
Total heroin consumption0.10.10.3-0.4-0.2-0.4-0.40.5-0.10.3
Bone: trabecular number0.50.81.91.00.71.00.9-1.4-0.10.5
Bone: trabecular spacing1.31.72.5-1.4-1.5-1.6-1.51.5-0.70.3
Bone: trabecular thickness0.91.11.40.91.01.21.1-1.01.1-1.0
Bone: trabecular tissue density1.01.42.11.51.41.21.3-1.01.0-0.8
Water consumed over 24 hours0.70.91.51.21.01.01.0-1.1-0.20.4
Number of responses in last shaping day0.80.81.50.50.90.60.9-0.71.2-1.2