Hub : Genes

Pgap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Pgap2 0.06 0.04 4.8e-04 0.02 0.02 0.02 0.02 2.2e-03 1.3e-03 3.3e-03 6.6e-03
2 Liver gene expression Pgap2 0.6 0.15 0.0e+00 0.36 0.4 0.41 0.42 3.1e-41 1.0e-47 3.1e-49 1.0e-50
3 Liver intron excision ratio chr1_166023418_166027545 0.05 0.04 4.1e-04 0.02 0.02 0.02 0.02 1.1e-03 5.0e-03 4.1e-03 2.9e-03
4 Adipose alternative TSS XM_063265230.1 0.03 0.03 9.2e-03 0 0.01 0 0 1.2e-01 3.9e-02 3.2e-01 1.3e-01
5 Adipose isoform ratio XM_006229837.5 0.05 0.03 6.7e-05 0.01 0.02 0.02 0.02 9.2e-03 1.3e-03 3.4e-03 5.6e-03
6 pVTA gene expression Pgap2 0.08 0.05 1.6e-06 0.04 0.09 0.07 0.07 3.4e-04 2.5e-07 1.5e-06 2.5e-06
7 NAcc gene expression Pgap2 0.06 0.04 9.9e-10 0.05 0.06 0.06 0.06 3.1e-08 4.4e-10 3.6e-09 1.5e-09
8 Brain alternative TSS XM_063265230.1 0.04 0.03 1.3e-03 0.03 0.03 0.01 0.02 9.8e-04 1.9e-03 1.3e-02 5.0e-03
9 Adipose alternative TSS XM_063265703.1 0.05 0.03 8.9e-04 0.03 0.03 0.03 0.02 7.4e-04 7.5e-04 8.0e-04 9.5e-04
10 Brain gene expression Pgap2 0.06 0.04 5.6e-06 0.04 0.05 0.05 0.04 1.1e-04 9.4e-06 1.5e-05 6.7e-05
11 Liver intron excision ratio chr1_166003815_166015050 0.06 0.05 2.6e-04 0.03 0.03 0.02 0.02 7.4e-04 6.6e-04 2.8e-03 1.3e-03
12 NAcc isoform ratio NM_053895.2 0.01 0.01 7.3e-03 0.02 0.01 0.01 0.01 1.1e-03 1.8e-02 1.6e-02 3.8e-03
13 PL gene expression Pgap2 0.04 0.03 5.3e-04 0.03 0.03 0.03 0.03 1.2e-04 1.8e-04 2.2e-04 1.7e-04
14 pVTA alternative TSS XM_063265230.1 0.04 0.03 3.3e-03 0.02 0.03 0.02 0.02 5.0e-03 3.7e-03 1.0e-02 1.1e-02
15 NAcc alternative TSS NM_053895.2 0.02 0.01 5.3e-03 0.02 0.01 0.02 0.02 6.5e-04 4.0e-03 1.3e-03 8.6e-04
16 NAcc alternative TSS NM_053895.2 0.02 0.01 9.8e-03 0.02 0.01 0.01 0.01 1.6e-03 1.2e-02 3.9e-03 2.8e-03
17 Brain isoform ratio NM_053895.2 0.03 0.03 1.6e-03 0.03 0.03 0.03 0.03 5.5e-04 1.2e-03 7.6e-04 2.0e-03
18 NAcc alternative TSS XM_063265230.1 0.03 0.02 1.2e-04 0.03 0.02 0.02 0.03 2.4e-05 1.9e-04 4.0e-04 7.6e-05
19 IL alternative TSS XM_063265703.1 0.14 0.1 8.1e-03 0.02 0.03 0.03 0.01 1.3e-01 6.1e-02 7.0e-02 1.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.20.4-0.6-0.6-0.6-0.50.6-0.7-0.5-0.2-0.3-0.60.20.3-0.3-0.10.40.40.50.40.2
Area under the delay curve0.40.51.5-1.0-0.8-0.7-1.10.3-0.3-0.1-1.2-1.1-0.01.1-0.40.4-1.0-0.4-0.4-0.2-0.3-0.5
BMI with tail0.93.25.90.40.2-0.11.21.2-1.3-1.82.01.5-1.7-1.92.3-2.32.32.42.41.91.92.4
BMI without tail0.82.37.42.01.91.52.3-0.60.5-0.02.72.1-0.0-2.30.9-0.92.30.90.90.80.81.4
Body weight0.20.82.51.31.31.61.1-1.21.20.80.91.21.0-0.6-0.40.40.6-0.5-0.5-0.7-0.6-0.2
Weight adjusted by age0.40.61.41.21.01.21.0-1.11.10.90.80.60.9-0.5-0.50.50.3-0.4-0.4-0.8-0.7-0.4
Bone surface0.40.81.40.80.90.90.5-1.11.11.20.10.01.10.1-1.21.2-0.3-1.0-1.0-0.9-1.0-0.9
Bone volume0.20.40.90.40.50.60.1-0.70.70.8-0.1-0.10.80.3-0.90.9-0.4-0.7-0.7-0.7-0.8-0.8
Breakpoint value in progressive ratio session0.70.91.7-1.1-0.8-1.2-0.71.3-1.2-1.2-0.4-0.3-1.20.10.8-0.80.20.90.91.01.20.9
Number of licking bursts1.42.35.7-2.4-2.3-2.1-2.21.9-1.8-1.7-1.6-1.3-1.51.40.8-0.8-1.00.90.90.90.80.4
Context. condit. distance diff. score2.02.46.12.42.52.12.4-1.51.31.12.42.10.9-2.0-0.30.31.7-0.0-0.0-0.1-0.10.3
Locomotion velocity, session 11.92.13.8-0.4-0.4-1.00.21.5-1.6-1.70.80.9-1.7-1.01.7-1.71.31.91.92.01.81.8
Locomotion distance, session 11.11.33.01.01.00.41.40.2-0.3-0.51.71.6-0.6-1.71.0-1.01.71.11.11.11.21.3
Locomotion velocity, session 21.01.22.20.40.5-0.10.90.7-0.7-0.91.11.3-1.0-1.31.1-1.11.51.31.31.41.51.4
Locomotion distance, session 21.11.53.20.80.80.21.30.4-0.5-0.81.41.7-0.9-1.71.2-1.21.81.31.31.41.41.5
Locomotion velocity, session 30.30.30.80.90.90.70.9-0.60.50.50.80.70.4-0.7-0.30.30.5-0.1-0.1-0.0-0.1-0.0
Locomotion distance, session 30.40.51.31.11.00.81.1-0.40.30.31.21.00.1-1.0-0.00.00.90.30.30.30.20.3
Stereotopy head waving bouts, day 30.50.61.0-0.4-0.4-0.0-0.7-0.40.50.5-0.8-0.90.71.0-0.70.7-1.0-1.0-1.0-1.0-0.8-0.9
Stereotopy head waving duration, day 30.20.20.50.70.60.60.7-0.40.40.30.70.50.3-0.60.2-0.20.5-0.2-0.2-0.2-0.00.1
Locomotion velocity, session 70.91.01.9-0.00.1-0.40.40.9-0.9-1.00.91.0-1.1-0.91.1-1.11.11.31.31.41.21.3
Locomotion distance, session 70.10.10.3-0.6-0.5-0.5-0.50.4-0.4-0.4-0.3-0.3-0.30.40.0-0.0-0.20.40.40.40.20.1
Stereotopy head waving bouts, day 71.82.15.32.32.22.02.2-1.61.51.41.81.61.1-1.6-0.60.61.2-0.7-0.7-0.6-0.4-0.2
Stereotopy head waving duration, day 71.72.15.62.42.32.02.3-1.61.41.31.91.71.0-1.7-0.40.41.3-0.5-0.5-0.5-0.3-0.0
Locomotion velocity, session 80.80.92.71.51.61.31.4-1.11.00.91.11.20.7-1.0-0.60.60.8-0.1-0.1-0.2-0.2-0.1
Locomotion distance, session 81.82.76.92.42.51.92.6-1.11.00.62.62.50.4-2.40.2-0.22.20.50.50.40.50.9
Degree of sensitization distance0.60.61.5-0.7-0.5-0.2-1.0-0.30.40.4-1.1-1.00.61.2-0.90.9-1.1-0.8-0.8-0.7-0.8-0.9
Degree of sensitization stereotypy3.33.69.13.03.02.72.8-2.22.01.92.32.21.5-2.1-0.90.91.5-0.8-0.8-0.7-0.6-0.2
Conditioned locomotion0.40.51.2-0.8-0.6-0.5-1.00.00.00.2-1.0-1.00.31.1-0.80.8-1.0-0.5-0.5-0.4-0.5-0.7
Cocaine response after cond. corrected0.70.82.0-1.4-1.4-1.3-1.31.1-1.0-0.9-1.0-0.9-0.80.90.5-0.5-0.60.40.40.40.40.2
Cocaine response after cond. not corrected0.60.71.2-0.8-0.9-1.0-0.51.1-1.1-1.1-0.1-0.2-1.10.01.1-1.10.20.90.90.90.90.8
Cocaine response before conditioning1.31.64.21.51.50.91.9-0.20.1-0.12.11.8-0.3-2.00.9-0.91.90.90.90.90.81.2
Saline control response2.33.15.41.61.62.00.9-2.32.32.30.20.12.20.2-2.02.0-0.6-2.1-2.1-1.9-2.0-1.8
Bone: connectivity density0.81.32.3-0.1-0.2-0.70.31.2-1.2-1.20.90.7-1.4-1.01.3-1.31.11.51.51.51.51.4
Bone: cortical apparent density0.71.02.6-1.6-1.5-1.4-1.60.9-0.8-0.7-1.6-1.3-0.51.30.2-0.2-1.1-0.1-0.10.10.1-0.2
Bone: cortical area0.10.10.40.30.50.50.2-0.50.50.40.00.20.50.1-0.60.6-0.1-0.3-0.3-0.2-0.4-0.3
Bone: cortical porosity0.10.20.3-0.2-0.2-0.1-0.3-0.20.20.3-0.4-0.50.30.4-0.50.5-0.5-0.5-0.5-0.4-0.4-0.5
Bone: cortical porosity0.20.20.30.10.00.2-0.1-0.40.40.5-0.2-0.40.50.3-0.50.5-0.4-0.6-0.6-0.6-0.5-0.6
Bone: cortical thickness0.71.12.2-0.7-0.7-1.0-0.31.3-1.3-1.40.10.3-1.3-0.31.2-1.20.61.31.31.51.31.2
Bone: cortical thickness0.00.00.10.10.20.30.1-0.20.20.10.10.30.1-0.1-0.20.20.0-0.2-0.20.0-0.0-0.1
Bone: cortical tissue density0.71.02.7-1.6-1.5-1.4-1.61.0-0.8-0.7-1.5-1.3-0.51.30.2-0.2-1.1-0.0-0.00.20.2-0.2
Condit. Reinf. active minus inactive responses1.71.93.60.60.61.20.0-1.61.61.7-0.5-0.51.70.8-1.61.6-1.1-1.8-1.8-1.8-1.9-1.7
Condit. Reinf. active-inactive response ratio3.13.36.30.70.71.4-0.1-2.02.12.2-0.8-0.92.21.2-2.22.2-1.5-2.3-2.3-2.4-2.5-2.3
Condit. Reinf. active responses1.01.22.2-0.1-0.10.4-0.6-0.90.91.1-1.0-1.11.21.2-1.21.2-1.3-1.4-1.4-1.5-1.5-1.4
Condit. Reinf. inactive responses0.30.30.8-0.8-0.8-0.9-0.60.8-0.7-0.7-0.4-0.5-0.70.30.5-0.5-0.10.50.50.40.50.4
Incentive salience index mean1.11.32.60.20.20.7-0.2-1.11.21.3-0.7-0.81.30.9-1.21.2-1.1-1.5-1.5-1.5-1.6-1.4
Condit. Reinf. lever presses0.00.00.10.1-0.00.10.0-0.10.10.1-0.0-0.00.10.00.1-0.1-0.1-0.2-0.2-0.2-0.2-0.1
Condit. Reinf. active minus inactive responses5.26.812.63.43.53.62.7-3.53.43.21.71.63.0-1.2-2.42.40.5-2.2-2.2-2.3-2.3-1.7
Condit. Reinf. active-inactive response ratio0.80.92.31.51.51.31.3-1.11.11.01.00.90.9-0.9-0.60.60.6-0.4-0.4-0.5-0.6-0.2
Condit. Reinf. active responses7.09.717.83.84.04.22.9-4.24.13.91.71.73.7-1.1-3.13.10.3-2.8-2.8-3.0-2.9-2.2
Condit. Reinf. inactive responses4.05.29.42.42.53.01.6-3.13.12.90.60.82.9-0.2-2.52.5-0.3-2.4-2.4-2.4-2.3-2.0
Condit. Reinf. lever presses8.511.725.35.05.05.04.4-4.44.23.83.13.13.5-2.6-2.52.51.8-2.2-2.2-2.3-2.3-1.3
Condit. Reinf. lever reinforcers received7.310.219.04.04.14.43.1-4.34.24.01.81.83.8-1.2-3.13.10.4-2.8-2.8-2.9-2.9-2.2
Conditioned reinforcement - actives0.00.10.40.20.3-0.10.30.1-0.1-0.10.5-0.0-0.2-0.40.1-0.10.40.10.10.60.30.3
Conditioned reinforcement - inactives0.71.02.5-1.3-1.3-1.1-1.50.3-0.2-0.1-1.6-1.60.11.5-0.40.4-1.4-0.4-0.4-0.7-0.7-0.8
Conditioned locomotion0.70.92.41.00.80.31.30.1-0.2-0.31.51.1-0.5-1.50.8-0.81.50.90.91.00.91.1
Patch foraging indifference point 0 sec1.11.94.92.22.12.22.1-1.61.51.21.51.91.1-1.5-0.50.51.2-0.7-0.7-0.6-0.2-0.1
Patch foraging indifference point AUC0.30.40.80.70.70.80.4-0.90.90.8-0.10.30.8-0.0-0.70.7-0.1-0.8-0.8-0.7-0.6-0.6
Delay disc. indifference point, 0s delay0.60.61.81.01.11.40.9-1.01.00.90.70.60.8-0.4-0.60.60.3-0.5-0.5-0.6-0.7-0.4
Delay disc. indifference point, 16s delay1.11.33.9-1.1-1.0-0.8-1.4-0.00.10.4-1.8-2.00.41.6-0.90.9-1.6-0.9-0.9-0.9-1.0-1.2
Delay disc. indifference point, 2s delay0.70.81.40.40.60.70.1-1.01.01.1-0.3-0.21.10.4-1.11.1-0.6-1.2-1.2-1.0-1.1-1.0
Delay disc. indifference point, 24s delay1.31.54.4-1.8-1.7-1.6-1.90.8-0.7-0.5-2.0-2.1-0.31.7-0.20.2-1.6-0.2-0.2-0.2-0.3-0.6
Delay disc. indifference point, 4s delay1.21.32.00.81.11.30.3-1.41.41.4-0.30.11.40.3-1.31.3-0.6-1.4-1.4-1.3-1.3-1.2
Delay disc. indifference point, 8s delay0.30.30.8-0.9-0.7-0.8-0.90.6-0.6-0.4-0.8-0.8-0.40.6-0.00.0-0.5-0.1-0.10.30.2-0.0
Indifference point function ln k0.10.10.50.40.30.40.5-0.0-0.1-0.10.70.5-0.2-0.60.4-0.40.50.30.30.20.20.3
Indifference point function log k0.10.10.50.40.30.40.5-0.0-0.1-0.10.70.5-0.2-0.60.4-0.40.50.30.30.20.20.3
Patch foraging total patch changes 0 sec0.91.84.52.12.02.12.0-1.41.31.01.51.90.9-1.5-0.30.31.3-0.5-0.5-0.4-0.10.1
Patch foraging total patch changes 12 sec0.81.01.91.21.31.40.9-1.31.41.20.30.71.2-0.3-1.11.10.1-1.1-1.1-1.0-0.6-0.7
Patch foraging total patch changes 18 sec0.61.02.11.41.51.41.2-1.21.21.10.61.01.0-0.7-0.80.80.5-0.8-0.8-0.7-0.3-0.3
Patch foraging total patch changes 24 sec0.81.33.11.41.31.81.0-1.51.51.30.60.81.4-0.3-1.21.20.1-1.0-1.0-1.2-1.0-0.8
Patch foraging total patch changes 6 sec0.60.92.91.51.41.71.4-1.11.10.81.01.20.8-0.9-0.10.10.7-0.3-0.3-0.6-0.4-0.1
Patch foraging time to switch 0 sec1.53.17.4-2.7-2.6-2.7-2.42.2-2.1-1.8-1.8-1.9-1.71.60.8-0.8-1.21.01.00.91.00.4
Patch foraging water rate 0 sec1.22.46.02.42.22.42.1-2.01.91.61.61.61.5-1.3-0.80.81.0-1.0-1.0-0.9-0.9-0.5
Patch foraging water rate 12 sec1.53.18.32.11.81.52.5-0.30.2-0.32.72.9-0.4-2.71.3-1.32.61.21.21.21.21.7
Patch foraging water rate 18 sec1.42.25.62.32.22.12.4-1.41.30.92.22.10.8-1.9-0.10.11.7-0.1-0.1-0.0-0.20.4
Patch foraging water rate 24 sec0.71.02.20.80.70.41.20.2-0.3-0.51.51.4-0.6-1.41.1-1.11.50.90.91.01.01.2
Patch foraging water rate 6 sec0.91.33.01.21.00.81.5-0.0-0.1-0.31.71.7-0.5-1.70.9-0.91.70.90.91.10.91.2
Seeking ratio, delayed vs. immediate footshock1.62.03.8-1.6-1.9-2.0-1.31.8-1.8-1.7-0.6-1.0-1.60.41.4-1.4-0.21.41.41.41.10.9
Distance traveled before self-admin0.70.91.7-0.3-0.5-0.50.11.0-1.0-1.10.50.8-1.1-0.61.1-1.10.81.31.31.01.21.1
Distance traveled after self-admin1.72.13.60.10.1-0.40.71.2-1.3-1.41.31.6-1.5-1.51.8-1.81.61.91.91.71.71.8
Extensor digitorum longus weight0.10.20.4-0.6-0.4-0.6-0.40.6-0.5-0.6-0.2-0.1-0.50.20.2-0.2-0.00.60.60.50.40.4
Bone: elastic displacement1.82.13.6-1.3-1.4-1.6-0.71.9-1.9-1.90.0-0.1-1.8-0.21.8-1.80.51.71.71.61.51.4
Bone: elastic work3.34.37.2-1.5-1.7-2.0-0.72.6-2.6-2.70.30.2-2.6-0.62.6-2.61.02.52.52.62.42.3
Bone: endosteal estimation1.32.95.41.21.41.70.6-2.12.12.2-0.1-0.12.10.5-2.32.3-0.8-1.9-1.9-1.9-2.0-1.8
Bone: endosteal perimeter1.53.25.41.71.92.11.1-2.32.32.30.50.42.20.0-2.12.1-0.4-1.8-1.8-1.9-1.9-1.7
Epididymis fat weight0.20.61.0-0.9-0.8-1.0-0.71.0-1.0-1.0-0.3-0.0-0.90.20.8-0.80.00.70.70.70.90.7
Delta time in closed arm before/after self-admin0.70.61.7-1.2-1.3-0.9-1.30.6-0.5-0.4-1.3-1.2-0.21.2-0.00.0-1.00.10.1-0.3-0.2-0.4
Delta time in open arm before/after self-admin2.32.34.31.81.82.01.3-2.12.02.00.70.91.9-0.3-1.51.5-0.1-1.3-1.3-1.7-1.5-1.3
Diff in mean of infusions in LGA sessions2.43.08.2-2.2-2.2-1.2-2.60.5-0.4-0.1-2.8-2.90.22.7-0.80.8-2.6-0.8-0.8-1.2-1.2-1.5
Delay discount exponential model param0.40.41.21.00.80.81.1-0.50.40.21.11.00.2-0.90.2-0.20.90.20.20.00.10.3
Extinction: sum of active levers before priming0.10.10.40.00.30.0-0.1-0.20.30.3-0.4-0.00.30.2-0.30.3-0.3-0.7-0.7-0.4-0.1-0.3
Active lever presses in extinction session 61.01.02.71.20.80.71.4-0.1-0.0-0.21.61.6-0.3-1.61.0-1.01.50.90.90.40.61.0
Bone: final force0.71.23.3-1.1-0.9-0.7-1.4-0.00.10.3-1.8-1.60.41.6-1.11.1-1.6-0.9-0.9-0.7-0.9-1.2
Bone: final moment0.60.92.2-0.8-0.7-0.4-1.2-0.20.20.4-1.5-1.30.51.4-1.01.0-1.4-0.8-0.8-0.7-0.9-1.1
Food consumed during 24 hour testing period1.21.74.42.12.01.82.1-1.21.11.02.01.80.7-1.7-0.10.11.4-0.2-0.2-0.1-0.20.2
Glucose0.30.51.10.20.1-0.30.50.5-0.6-0.60.60.2-0.7-0.80.7-0.70.90.80.81.01.00.9
Heart weight0.91.43.61.41.41.91.0-1.61.51.40.31.31.4-0.3-1.01.00.0-0.9-0.9-1.4-1.2-0.9
Delay discount hyperbolic model param0.40.41.20.90.70.61.0-0.30.20.01.11.00.0-1.00.4-0.40.90.40.40.20.30.5
Intermittent access intake day 1-15 change1.12.34.31.10.70.51.60.5-0.6-1.02.01.8-1.0-2.01.8-1.82.11.91.91.61.21.8
Intermittent access intake escalation1.02.04.31.31.00.81.70.2-0.3-0.62.01.8-0.7-2.11.5-1.52.01.71.71.40.91.6
Intermittent access intake escalation 20.40.51.10.50.50.40.80.2-0.3-0.40.91.0-0.4-1.00.7-0.71.00.80.80.80.50.8
Intermitt. access day 1 inactive lever presses0.41.64.6-2.0-1.8-1.3-2.11.0-0.9-0.7-2.1-1.5-0.41.9-0.00.0-1.7-0.0-0.0-0.3-0.5-0.6
Intermitt. access day 15 inactive lever presses0.10.20.5-0.6-0.7-0.3-0.60.3-0.3-0.3-0.6-0.5-0.20.50.3-0.3-0.50.30.3-0.1-0.5-0.2
Intermitt. access escalation Index0.10.10.2-0.00.00.0-0.1-0.30.30.4-0.3-0.40.40.3-0.30.3-0.4-0.4-0.4-0.4-0.5-0.4
Intermittent access day 1 total infusions0.40.71.30.91.11.00.7-1.11.11.10.2-0.01.0-0.2-1.01.0-0.0-1.0-1.0-0.5-0.7-0.7
Intermittent access day 15 total infusions0.30.41.21.11.00.81.1-0.60.50.50.90.60.3-0.9-0.00.00.80.10.10.3-0.10.2
Intermittent access terminal intake (last 3 days)0.40.51.41.11.21.01.1-0.80.70.71.00.70.6-0.8-0.40.40.6-0.3-0.30.2-0.2-0.1
Intermittent access total infusions0.40.41.41.01.20.81.0-0.70.70.70.80.50.5-0.8-0.40.40.6-0.4-0.40.2-0.1-0.0
Intermittent access day 1 locomotion0.30.40.9-0.1-0.1-0.0-0.3-0.40.40.6-0.6-1.00.60.6-0.70.7-0.7-0.7-0.7-0.6-0.7-0.8
Intermittent access day 15 total locomotion0.30.61.00.30.2-0.60.70.4-0.5-0.50.90.1-0.7-1.00.9-0.91.00.90.91.00.80.9
Intermittent access total locomotion0.10.10.40.70.60.30.6-0.50.40.50.5-0.10.3-0.5-0.20.20.3-0.1-0.10.0-0.2-0.1
Intermittent access standard deviation0.20.40.90.30.10.40.50.2-0.3-0.50.70.9-0.4-0.70.9-0.90.81.01.00.50.40.7
Left kidney weight0.10.51.71.11.01.31.0-0.90.80.50.80.80.6-0.6-0.10.10.6-0.1-0.1-0.6-0.40.0
Right kidney weight0.31.33.51.31.21.90.9-1.61.61.30.30.51.5-0.1-0.90.9-0.1-0.9-0.9-1.5-1.4-0.9
Cocaine induced anxiety1.52.15.8-2.3-2.4-1.8-2.41.2-1.1-0.9-2.2-2.0-0.62.00.1-0.1-1.80.00.0-0.2-0.3-0.6
Post-drug Anxiety2.02.15.1-1.6-1.7-1.2-2.00.2-0.00.3-2.2-2.30.42.2-1.01.0-2.2-1.1-1.1-1.1-1.2-1.5
Baseline Anxiety1.92.24.01.51.41.61.0-2.02.02.00.40.11.9-0.1-1.61.6-0.3-1.7-1.7-1.5-1.5-1.4
Tail length2.59.916.32.32.53.21.1-3.94.04.0-0.3-0.14.00.9-3.73.7-1.6-3.9-3.9-3.8-3.6-3.4
Length with tail1.98.413.81.92.23.00.8-3.63.73.7-0.60.43.71.0-3.53.5-1.6-3.6-3.6-3.6-3.2-3.2
Length without tail0.10.40.80.10.20.6-0.2-0.60.70.6-0.60.10.70.5-0.70.7-0.6-0.7-0.7-0.9-0.7-0.8
Times rat made contact with spout0.20.20.6-0.6-0.6-0.4-0.70.1-0.10.0-0.7-0.70.10.8-0.30.3-0.7-0.3-0.3-0.3-0.4-0.5
Lifetime Intake0.60.72.01.31.41.01.3-0.90.90.81.00.70.6-1.0-0.50.50.8-0.4-0.40.2-0.1-0.0
Liver weight, left0.40.61.5-0.8-0.6-0.5-1.1-0.00.10.2-1.1-0.60.41.2-0.90.9-1.2-0.6-0.6-0.7-0.5-0.8
Liver weight, right0.61.12.5-0.8-0.6-0.3-1.2-0.40.50.6-1.6-1.20.81.6-1.21.2-1.5-1.1-1.1-1.1-1.0-1.2
Locomotor activity0.30.51.41.11.11.11.2-0.60.60.41.11.10.3-1.00.1-0.10.90.20.20.0-0.10.3
Locomotor testing distance0.81.43.61.81.91.81.7-1.41.31.11.41.41.0-1.2-0.60.60.9-0.4-0.4-0.4-0.6-0.2
Locomotor testing rearing0.40.91.51.11.21.20.8-1.21.21.20.50.61.1-0.2-1.11.10.1-0.9-0.9-0.8-0.7-0.7
Locomotion in novel chamber0.91.22.4-0.6-0.7-0.7-0.21.3-1.3-1.40.30.1-1.4-0.51.6-1.60.71.41.41.31.11.2
Locomotion in novel chamber post-restriction0.30.51.31.01.10.51.1-0.30.20.20.90.9-0.0-1.10.2-0.21.00.30.30.30.40.5
Fecal boli incidents, locomotor time 10.81.13.0-1.7-1.6-1.4-1.61.3-1.2-0.9-1.4-1.0-0.91.10.4-0.4-0.90.40.40.80.30.1
Change in fecal boli incidents, locomotor task0.20.20.50.60.70.20.5-0.50.50.40.30.10.4-0.3-0.20.20.3-0.5-0.5-0.5-0.0-0.1
Time >=10cm from walls, locomotor time 10.60.61.10.80.70.70.6-1.01.01.00.2-0.31.0-0.1-0.80.8-0.1-1.0-1.0-0.9-0.8-0.7
Bouts of movement, locomotor time 10.81.02.70.0-0.10.2-0.4-0.90.91.0-1.0-1.21.11.0-1.01.0-1.2-0.8-0.8-1.4-1.7-1.3
Total resting periods, locomotor time 10.30.31.2-0.3-0.5-0.4-0.6-0.20.20.3-0.9-1.10.40.7-0.40.4-0.8-0.3-0.3-0.7-1.0-0.7
Rest time, locomotor task time 10.10.20.8-0.2-0.1-0.6-0.4-0.10.10.3-0.4-0.90.20.4-0.50.5-0.5-0.4-0.4-0.2-0.3-0.4
Distance moved, locomotor task time 10.10.10.20.10.00.20.20.2-0.2-0.30.40.3-0.3-0.30.3-0.30.40.40.40.30.40.4
Vertical activity count, locomotor time 10.00.00.1-0.2-0.20.3-0.2-0.00.10.0-0.3-0.10.10.3-0.10.1-0.3-0.2-0.2-0.3-0.1-0.2
Time >=10cm from walls, locomotor time 22.53.66.11.61.62.00.9-2.42.42.50.1-0.32.40.3-2.12.1-0.7-2.4-2.4-2.3-2.1-2.0
Bouts of movement, locomotor time 21.72.74.5-0.20.10.4-0.9-1.31.41.6-1.8-1.81.71.7-2.12.1-1.9-1.9-1.9-1.9-2.0-2.1
Total resting periods, locomotor time 21.11.93.7-0.7-0.3-0.3-1.2-0.70.81.1-1.9-1.91.11.7-1.71.7-1.8-1.5-1.5-1.4-1.5-1.7
Rest time, locomotor task time 21.41.74.4-1.8-1.6-2.1-1.51.7-1.7-1.6-0.9-0.9-1.50.70.9-0.9-0.31.21.21.31.10.8
Distance moved, locomotor task time 21.31.53.11.81.71.71.5-1.61.61.51.20.81.4-0.8-0.90.90.5-1.0-1.0-1.0-0.9-0.6
Vertical activity count, locomotor time 20.50.71.70.30.50.7-0.1-0.90.91.0-0.5-0.21.00.5-1.11.1-0.7-1.3-1.3-1.0-0.8-1.0
Light reinforcement 11.23.05.4-1.6-1.6-1.9-0.92.3-2.2-2.3-0.2-0.1-2.2-0.11.9-1.90.62.12.12.02.11.8
Light reinforcement 22.94.57.90.30.2-0.71.21.7-1.8-2.11.92.0-2.2-2.22.5-2.52.52.62.62.62.82.8
Bone: marrow area1.22.54.91.01.21.50.4-1.91.92.0-0.2-0.22.00.6-2.22.2-0.9-1.8-1.8-1.8-1.9-1.8
Bone: maximum diameter1.32.54.41.81.92.11.3-2.12.12.00.70.81.9-0.3-1.81.8-0.0-1.5-1.5-1.4-1.5-1.2
Bone: maximum force0.20.41.2-0.8-0.5-0.5-0.90.1-0.10.1-1.1-0.90.10.9-0.70.7-0.9-0.4-0.4-0.2-0.3-0.6
Bone: maximum moment0.10.20.5-0.4-0.2-0.3-0.60.00.00.1-0.7-0.60.10.6-0.60.6-0.6-0.2-0.2-0.1-0.3-0.4
Mean time between licks in bursts3.27.913.12.22.33.01.2-3.63.63.60.2-0.13.60.6-3.33.3-1.2-3.3-3.3-3.4-3.4-3.0
Mean num. licks in bursts1.32.04.72.22.11.91.9-1.81.71.71.41.01.5-1.1-0.90.90.7-1.0-1.0-1.0-1.0-0.6
Cd content in liver0.40.51.0-0.6-0.4-0.4-0.8-0.10.20.4-0.9-1.00.41.0-0.80.8-1.0-0.7-0.7-0.5-0.5-0.8
Co content in liver2.22.54.21.01.11.40.4-1.92.02.0-0.4-0.52.00.6-1.91.9-0.9-2.0-2.0-1.8-2.0-1.8
Cu content in liver1.41.62.60.50.61.00.0-1.41.51.5-0.6-0.51.60.8-1.61.6-1.0-1.6-1.6-1.6-1.6-1.5
Fe content in liver0.00.10.2-0.3-0.3-0.2-0.30.0-0.00.0-0.4-0.40.10.4-0.10.1-0.4-0.2-0.2-0.1-0.2-0.2
K content in liver0.20.20.5-0.7-0.7-0.5-0.70.3-0.3-0.3-0.7-0.7-0.20.60.1-0.1-0.5-0.0-0.0-0.1-0.1-0.2
Mg content in liver0.20.20.30.20.20.10.40.2-0.2-0.30.50.5-0.3-0.50.6-0.60.60.40.40.40.40.5
Mn content in liver2.02.23.8-1.2-1.2-1.6-0.61.9-1.9-1.90.00.1-1.9-0.31.7-1.70.61.81.81.81.91.6
Na content in liver0.40.51.31.11.00.81.1-0.40.30.21.01.00.1-1.10.2-0.20.90.30.30.10.30.4
Rb content in liver0.40.40.80.10.10.1-0.2-0.60.60.8-0.6-0.80.70.5-0.80.8-0.7-0.9-0.9-0.8-0.9-0.9
Se content in liver3.34.08.3-2.8-2.8-2.9-2.32.7-2.6-2.3-1.6-1.6-2.21.21.4-1.4-0.81.61.61.51.51.0
Sr content in liver1.81.53.21.00.80.51.40.3-0.4-0.71.81.7-0.8-1.81.3-1.31.81.31.31.21.31.5
Zn content in liver1.31.43.51.91.81.81.7-1.41.31.11.31.41.0-1.2-0.40.41.0-0.5-0.5-0.6-0.5-0.1
Bone: minimum diameter1.12.04.00.60.91.20.1-1.61.71.7-0.4-0.41.80.8-2.02.0-1.0-1.7-1.7-1.5-1.7-1.7
Time in familiar zone, hab. session 10.10.10.40.50.60.40.5-0.30.30.20.40.50.2-0.4-0.20.20.4-0.0-0.00.20.10.1
Time in novel zone, hab. session 10.40.40.9-0.6-0.7-0.3-0.80.00.10.2-0.9-0.90.20.9-0.40.4-0.9-0.4-0.4-0.7-0.6-0.7
Total zone transitions, hab. session 10.30.40.90.50.50.20.80.2-0.2-0.30.90.8-0.4-1.00.5-0.50.90.80.80.70.70.7
Total locomotion distance, hab. session 10.60.91.5-0.4-0.40.1-0.8-0.60.70.7-1.0-1.00.91.2-1.01.0-1.2-1.2-1.2-1.2-1.0-1.2
Locomotion velocity, hab. session 10.30.51.0-0.4-0.4-0.1-0.7-0.40.40.4-0.8-0.90.61.0-0.70.7-0.9-0.8-0.8-0.8-0.7-0.8
Time in familiar zone, hab. session 22.42.64.61.71.82.01.2-2.12.12.10.40.62.0-0.2-1.81.8-0.2-1.7-1.7-1.6-1.6-1.4
Time in novel zone, hab. session 22.62.64.5-0.9-1.1-1.4-0.31.9-1.9-2.00.50.4-2.0-0.72.1-2.11.02.12.11.91.91.8
Total zone transitions, hab. session 21.41.84.82.22.01.92.2-1.21.10.81.91.80.7-1.80.1-0.11.50.10.1-0.2-0.10.4
Total locomotion distance, hab. session 20.91.22.20.70.81.20.3-1.41.51.3-0.1-0.11.50.4-1.21.2-0.5-1.3-1.3-1.4-1.3-1.1
Locomotion velocity, hab. session 20.91.22.10.60.61.10.2-1.31.41.3-0.3-0.21.40.6-1.31.3-0.7-1.4-1.4-1.5-1.3-1.2
Novel to familiar place preference ratio2.42.65.0-0.1-0.30.6-0.9-1.31.41.5-1.4-1.61.71.7-1.71.7-1.9-2.0-2.0-2.2-2.2-2.1
Novelty place preference2.12.34.5-0.1-0.20.6-0.7-1.31.41.5-1.2-1.41.61.5-1.71.7-1.8-1.8-1.8-2.1-2.1-2.0
Time in novel zone, NPP test2.42.65.10.1-0.00.8-0.6-1.51.61.7-1.1-1.31.81.5-1.81.8-1.7-2.0-2.0-2.3-2.2-2.1
Total zone transitions, NPP test1.21.73.00.50.5-0.11.10.8-0.9-1.11.51.4-1.2-1.61.5-1.51.71.61.61.51.51.7
Total locomotion distance, NPP test0.20.20.5-0.3-0.4-0.4-0.10.5-0.5-0.70.20.2-0.5-0.10.7-0.70.40.50.50.50.60.6
Locomotion velocity, NPP test0.40.51.1-0.6-0.7-0.7-0.30.9-0.8-1.00.10.1-0.9-0.10.9-0.90.40.80.80.80.90.9
Intraocular pressure0.20.30.80.1-0.2-0.30.30.5-0.6-0.60.50.2-0.7-0.60.9-0.90.60.70.70.60.60.7
Delta distance traveled before/after self-admin0.60.61.81.11.30.90.9-1.01.01.00.60.50.9-0.5-0.60.60.3-0.7-0.7-0.4-0.6-0.4
Delta ambulatory time before/after self-admin0.40.51.31.11.10.81.0-0.80.80.80.80.60.6-0.6-0.40.40.4-0.5-0.5-0.2-0.4-0.2
Parametrial fat weight1.63.76.8-0.6-0.6-1.20.32.0-2.1-2.21.21.5-2.3-1.42.3-2.31.82.22.22.62.62.4
Pavlov. Cond. lever latency0.60.81.4-0.7-0.7-0.8-0.41.1-1.1-1.20.00.2-1.1-0.11.1-1.10.41.11.10.90.90.9
Pavlov. Cond. magazine entry latency1.82.35.22.22.32.22.0-2.01.91.71.41.31.6-1.2-1.01.00.8-1.1-1.1-0.9-0.9-0.6
Pavlov. Cond. change in total contacts1.61.72.90.90.91.10.4-1.61.61.7-0.2-0.41.60.4-1.61.6-0.7-1.6-1.6-1.5-1.5-1.5
Pavlov. Cond. index score1.21.52.81.71.71.61.3-1.71.61.60.80.61.4-0.6-1.21.20.3-1.2-1.2-0.9-0.9-0.8
Pavlov. Cond. latency score1.21.52.61.51.51.41.1-1.61.61.60.60.41.4-0.4-1.21.20.1-1.3-1.3-1.0-1.0-0.9
Pavlov. Cond. lever contacts0.50.61.10.90.90.90.7-1.01.01.00.30.20.9-0.2-0.90.9-0.0-0.9-0.9-0.7-0.7-0.6
Pavlov. Cond. magazine entry number1.72.24.2-2.0-2.0-2.0-1.72.0-1.9-1.8-1.1-0.9-1.70.91.2-1.2-0.51.31.31.11.10.8
Pavlov. Cond. intertrial magazine entries0.50.61.5-1.2-1.2-1.1-1.10.8-0.7-0.6-1.1-1.1-0.50.90.1-0.1-0.80.10.10.10.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.01.32.31.51.51.41.2-1.51.51.50.70.51.3-0.6-1.11.10.2-1.1-1.1-0.9-0.9-0.7
Pavlov. Cond. response bias0.70.92.11.41.41.31.3-1.21.21.10.90.81.0-0.8-0.70.70.5-0.7-0.7-0.5-0.5-0.4
Pavlov. Cond. lever latency9.613.131.7-5.6-5.6-5.3-5.24.3-4.1-3.6-4.1-4.1-3.23.61.8-1.8-2.81.71.71.61.60.6
Pavlov. Cond. magazine entry latency3.74.512.12.92.82.23.3-0.90.70.33.53.40.0-3.20.9-0.93.00.90.91.11.01.6
Pavlov. Cond. change in total contacts7.111.328.25.35.24.95.0-4.03.83.33.93.82.9-3.4-1.51.52.7-1.5-1.5-1.5-1.4-0.4
Pavlov. Cond. index score7.09.423.54.94.84.44.7-3.33.12.63.93.92.3-3.5-1.01.02.9-0.9-0.9-0.8-0.80.1
Pavlov. Cond. latency score6.28.220.94.64.54.14.5-2.92.72.23.93.91.9-3.5-0.70.73.0-0.6-0.6-0.5-0.50.4
Pavlov. Cond. lever contacts8.912.329.15.45.35.24.9-4.34.13.63.73.83.3-3.2-1.91.92.4-1.8-1.8-1.8-1.8-0.8
Pavlov. Cond. magazine entry number4.75.815.4-3.7-3.6-3.1-3.91.9-1.7-1.2-3.7-3.6-0.93.4-0.20.2-3.1-0.2-0.2-0.3-0.4-1.1
Pavlov. Cond. intertrial magazine entries1.62.44.20.10.10.7-0.6-1.41.51.7-1.3-1.31.71.4-1.81.8-1.7-1.9-1.9-2.1-2.0-2.0
Pavlov. Cond. lever-magazine prob. diff.6.89.122.74.84.74.44.6-3.33.12.73.83.82.3-3.4-1.11.12.8-1.0-1.0-0.9-0.90.0
Pavlov. Cond. response bias9.312.731.55.65.55.35.3-4.13.83.34.34.42.9-3.8-1.41.43.1-1.4-1.4-1.3-1.2-0.2
Time in closed arm before self-admin1.21.64.12.01.91.42.0-1.31.20.91.91.80.8-1.6-0.20.21.3-0.4-0.4-0.1-0.40.2
Time in closed arm after self-admin0.30.30.9-0.8-0.9-1.0-0.80.6-0.6-0.5-0.6-0.7-0.40.60.3-0.3-0.40.30.30.20.10.0
Time in open arm before self-admin3.63.97.1-2.6-2.7-2.4-2.12.7-2.6-2.5-1.5-1.4-2.30.91.8-1.8-0.41.71.71.51.61.3
Time in open arm after self-admin0.20.20.60.20.20.70.0-0.50.50.5-0.2-0.10.60.2-0.40.4-0.3-0.4-0.4-0.7-0.5-0.5
Bone: periosteal estimation0.61.22.50.91.11.20.5-1.41.41.40.10.21.40.2-1.61.6-0.4-1.1-1.1-1.0-1.2-1.1
Bone: periosteal perimeter0.71.22.41.31.41.61.0-1.51.41.30.60.71.3-0.3-1.21.20.1-0.8-0.8-0.9-1.0-0.8
Bone: post-yield work0.10.10.30.40.50.40.3-0.30.30.30.20.40.3-0.2-0.50.50.2-0.1-0.1-0.0-0.0-0.1
Progressive ratio test 1 active lever presses0.00.00.1-0.0-0.1-0.2-0.00.0-0.10.1-0.0-0.3-0.00.0-0.00.0-0.10.00.00.2-0.1-0.1
Progressive ratio test 1 breakpoint0.00.00.1-0.1-0.1-0.3-0.10.1-0.10.1-0.1-0.4-0.00.0-0.10.1-0.1-0.0-0.00.2-0.0-0.1
Progressive ratio test 1 inactive lever presses0.20.31.0-0.9-0.7-1.0-0.80.7-0.6-0.5-0.7-0.8-0.50.50.2-0.2-0.50.20.20.20.20.0
Progressive ratio test 2 active lever presses0.10.10.10.20.3-0.10.1-0.20.20.40.0-0.30.2-0.0-0.40.4-0.1-0.4-0.40.0-0.1-0.2
Progressive ratio test 2 breakpoint0.10.10.20.30.40.00.2-0.30.30.40.1-0.20.2-0.1-0.40.40.0-0.4-0.40.0-0.1-0.2
Progressive ratio test 2 inactive lever presses0.10.10.30.00.0-0.40.20.3-0.3-0.20.20.0-0.3-0.30.3-0.30.30.30.30.60.30.4
Incentive Sensitization - Responses0.10.10.50.40.70.30.3-0.40.40.50.10.20.3-0.2-0.50.50.1-0.5-0.5-0.0-0.0-0.2
Incentive Sensitization - Breakpoint0.10.10.50.40.70.20.4-0.20.20.20.30.30.1-0.4-0.20.20.3-0.2-0.20.30.30.1
Sum of active levers in priming session hrs 5-60.20.20.80.50.60.40.6-0.00.0-0.10.70.9-0.1-0.60.3-0.30.70.20.20.20.40.5
Progressive ratio0.91.43.71.10.80.71.40.1-0.3-0.51.91.7-0.6-1.71.1-1.11.71.21.20.81.01.3
Food seeking constrained by brief footshock1.41.73.41.71.61.51.4-1.81.81.60.90.51.6-0.5-1.01.00.3-1.1-1.1-1.4-1.3-0.9
Seeking ratio, punishment vs. effort1.01.42.80.50.80.70.0-1.31.41.5-0.7-0.31.50.7-1.61.6-0.8-1.7-1.7-1.3-1.4-1.4
Retroperitoneal fat weight0.41.64.1-2.0-1.8-1.9-1.71.6-1.5-1.5-1.2-0.8-1.21.10.8-0.8-0.60.60.61.01.00.6
Reaction time number correct0.10.20.60.10.0-0.20.30.4-0.4-0.50.40.4-0.5-0.60.6-0.60.60.50.50.80.60.7
Reaction time mean minus median0.20.61.10.70.80.90.4-1.01.01.00.3-0.01.00.1-0.90.9-0.3-0.7-0.7-0.8-1.0-0.8
Reaction time mean minus median AUC0.10.30.70.60.80.70.5-0.80.80.70.40.10.8-0.1-0.60.6-0.0-0.5-0.5-0.4-0.6-0.5
Reaction time num false alarms1.52.15.6-2.2-2.1-2.0-2.31.1-0.9-0.7-2.2-2.4-0.52.1-0.10.1-1.8-0.2-0.2-0.2-0.4-0.7
Reaction time num false alarms AUC1.21.84.6-2.1-1.9-2.0-2.11.2-1.1-0.9-1.9-2.1-0.71.80.1-0.1-1.50.00.00.2-0.1-0.3
Reaction time trials correct on left0.10.20.60.10.0-0.20.30.4-0.4-0.50.40.4-0.5-0.60.6-0.60.60.50.50.80.60.7
Reaction time trials on left0.20.30.70.1-0.0-0.30.30.4-0.5-0.50.40.4-0.6-0.60.7-0.70.70.50.50.80.70.7
Reaction time mean1.11.84.7-1.9-1.7-1.5-2.20.6-0.4-0.2-1.9-2.20.02.2-0.70.7-1.9-0.7-0.7-0.5-0.8-1.0
Reaction time mean AUC1.32.05.3-2.1-1.9-1.7-2.30.7-0.6-0.3-2.0-2.3-0.12.2-0.60.6-2.0-0.6-0.6-0.4-0.7-1.0
Median of all reaction times1.72.46.6-2.4-2.2-2.1-2.61.1-0.9-0.6-2.2-2.4-0.42.3-0.50.5-2.0-0.4-0.4-0.2-0.4-0.8
Reaction time omissions0.20.20.7-0.8-0.7-0.8-0.70.6-0.5-0.5-0.3-0.6-0.40.50.3-0.3-0.30.10.10.40.30.1
Reaction time false alarm rate1.21.74.4-2.1-1.9-1.8-2.11.1-1.0-0.8-1.9-2.0-0.61.80.0-0.0-1.50.10.10.0-0.2-0.4
Reaction time premature initiation rate1.41.93.71.41.61.81.0-1.91.91.80.30.51.8-0.1-1.51.5-0.2-1.4-1.4-1.4-1.4-1.2
Reaction time premature initiations0.50.81.81.21.41.31.0-1.31.31.10.50.71.1-0.4-0.80.80.3-0.8-0.8-0.6-0.7-0.5
Std. dev. reaction times0.91.62.7-0.5-0.3-0.0-1.0-0.80.91.1-1.2-1.51.21.6-1.61.6-1.7-1.5-1.5-1.4-1.6-1.7
Reaction time trials completed0.20.30.70.1-0.0-0.30.30.4-0.5-0.50.40.4-0.6-0.60.7-0.70.70.50.50.80.70.7
Reaction time trials AUC0.10.10.40.10.0-0.20.30.3-0.3-0.40.30.3-0.4-0.40.5-0.50.50.30.30.60.50.5
Run reversals in cocaine runway, females0.50.51.10.70.71.00.5-0.91.00.80.50.30.9-0.0-0.70.7-0.1-0.6-0.6-0.8-0.7-0.5
Run reversals in cocaine runway, males0.30.30.9-0.8-1.0-0.7-0.80.7-0.6-0.6-0.5-0.7-0.50.50.3-0.3-0.40.20.20.10.20.1
Latency to leave start box in cocaine runway0.81.02.9-1.7-1.2-1.3-1.71.1-0.9-0.8-1.5-1.0-0.71.3-0.10.1-1.00.00.00.30.5-0.1
Latency to leave start box in cocaine runway, F1.21.44.0-1.6-1.1-0.9-1.90.4-0.2-0.0-2.0-1.60.21.9-0.90.9-1.7-0.9-0.9-0.7-0.4-1.0
Latency to leave start box in cocaine runway, M1.21.12.3-0.7-0.5-1.0-0.21.3-1.3-1.30.10.4-1.4-0.41.1-1.10.71.21.21.41.51.2
Std. dev. time between licks in bursts2.12.94.80.80.91.40.1-2.02.02.0-0.7-0.52.11.0-2.22.2-1.2-2.1-2.1-2.2-2.1-2.0
Total sessions with >9 infusions0.81.03.21.51.81.21.5-1.11.11.11.01.10.8-1.1-0.70.70.9-0.7-0.70.1-0.1-0.1
Short access day 1 total inactive lever presses0.30.51.2-0.5-0.3-0.1-0.8-0.20.30.4-1.1-0.60.41.0-0.80.8-1.0-0.8-0.8-0.6-0.6-0.8
Short access day 10 total inactive lever presses0.51.23.1-1.7-1.7-1.5-1.81.0-0.9-0.8-1.7-1.3-0.61.40.2-0.2-1.20.20.2-0.1-0.2-0.3
Short access day 1 total infusions1.52.03.61.61.91.81.3-1.91.91.80.60.61.7-0.4-1.61.60.1-1.6-1.6-0.9-1.0-1.0
Short access day 10 total infusions0.60.82.51.31.61.21.3-0.90.90.91.10.90.6-1.0-0.60.60.8-0.5-0.50.30.00.0
Short access total infusions1.01.23.21.61.81.61.5-1.41.31.31.00.91.1-0.9-0.90.90.6-0.9-0.9-0.2-0.5-0.4
Short access day 1 locomotion0.40.41.11.01.01.01.1-0.40.40.31.01.00.2-1.00.1-0.10.80.20.20.40.00.3
Short access day 10 total locomotion0.20.41.10.91.00.71.0-0.30.20.11.01.1-0.0-1.00.3-0.30.90.30.30.40.40.5
Short access total locomotion0.20.20.50.30.40.00.50.2-0.2-0.20.70.5-0.4-0.70.4-0.40.70.50.50.70.50.6
One hour access (0.3 mA shock)0.30.41.00.80.80.51.0-0.10.1-0.00.91.0-0.1-1.00.3-0.31.00.40.40.50.50.6
Compulsive drug intake1.11.32.4-0.8-1.3-0.9-0.51.4-1.4-1.50.00.4-1.4-0.21.5-1.50.41.51.50.91.01.1
One hour access (shock baseline)0.61.02.91.51.71.21.6-0.80.70.61.41.40.4-1.4-0.10.11.2-0.1-0.10.40.30.4
Social response proportion0.20.20.6-0.6-0.7-0.2-0.60.3-0.3-0.3-0.7-0.5-0.20.50.5-0.5-0.40.20.2-0.3-0.1-0.1
Social responses0.50.61.9-0.7-0.7-0.2-1.0-0.20.30.3-1.4-1.10.51.2-0.60.6-1.1-0.7-0.7-0.9-0.7-0.9
Social time1.41.94.4-1.8-1.7-2.1-1.51.8-1.8-1.6-1.1-1.0-1.60.71.1-1.1-0.31.01.01.21.30.8
Soleus weight0.30.81.9-0.9-0.7-0.5-1.1-0.10.20.3-1.2-1.10.51.4-0.80.8-1.3-1.0-1.0-0.7-0.7-0.9
Bone: stiffness1.32.25.0-1.4-1.1-0.8-1.9-0.10.30.6-2.2-2.00.72.2-1.51.5-2.2-1.4-1.4-1.2-1.2-1.7
Tibialis anterior weight0.10.40.90.00.20.3-0.2-0.60.60.7-0.4-0.40.70.6-1.01.0-0.6-0.6-0.6-0.7-0.8-0.8
Time to tail flick, vehicle, before self-admin0.70.72.21.21.01.11.3-0.50.40.21.51.40.1-1.20.5-0.51.10.40.40.40.00.5
Time to tail flick, vehicle, after self-admin0.50.71.20.71.00.80.4-1.01.01.10.00.11.00.0-1.11.1-0.3-1.0-1.0-1.0-0.8-0.8
Time to tail flick, test, before self-admin2.72.85.21.71.62.21.1-2.32.22.20.10.42.2-0.0-1.61.6-0.4-1.8-1.8-2.1-1.9-1.6
Time to tail flick, test, after self-admin2.93.15.50.80.81.50.1-2.02.12.1-0.8-1.12.21.0-2.12.1-1.3-2.1-2.1-2.3-2.3-2.1
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.4-0.2-0.2-0.6-0.10.20.4-0.9-0.90.30.7-0.80.8-0.8-0.5-0.5-0.6-0.3-0.6
Delta time to tail flick, test, before/after SA0.60.61.2-1.0-1.1-1.1-0.91.0-0.9-1.0-0.4-0.8-0.80.50.6-0.6-0.20.70.70.60.40.4
Tibia length0.30.71.41.21.21.11.0-1.11.01.10.50.50.9-0.5-0.80.80.2-0.6-0.6-0.7-0.7-0.5
Ambulatory time before self-admin0.60.91.5-0.6-0.5-0.7-0.21.1-1.1-1.20.20.4-1.2-0.41.0-1.00.61.21.21.11.21.1
Ambulatory time after self-admin0.91.12.00.60.7-0.11.00.5-0.6-0.71.21.4-0.8-1.41.1-1.11.41.21.21.31.11.2
Bone: tissue strength2.52.54.4-0.4-0.5-1.10.31.6-1.7-1.80.90.7-1.9-1.22.0-2.01.42.12.12.12.02.0
Total heroin consumption0.20.30.80.60.60.60.8-0.10.0-0.10.80.9-0.1-0.80.4-0.40.80.30.30.30.40.6
Bone: trabecular number1.01.63.0-1.2-1.2-1.6-0.81.7-1.7-1.6-0.0-0.2-1.7-0.11.3-1.30.31.41.41.51.51.2
Bone: trabecular spacing0.60.82.01.00.90.61.3-0.10.0-0.21.31.4-0.3-1.40.8-0.81.40.40.40.70.70.9
Bone: trabecular thickness1.31.63.0-0.7-0.6-0.1-1.2-0.60.70.9-1.6-1.51.01.7-1.51.5-1.7-1.3-1.3-1.3-1.4-1.6
Bone: trabecular tissue density2.84.19.5-1.9-1.6-0.9-2.6-0.30.50.8-3.1-2.81.13.1-1.91.9-3.0-1.8-1.8-1.8-1.9-2.3
Water consumed over 24 hours0.10.20.4-0.6-0.6-0.5-0.50.5-0.5-0.4-0.4-0.3-0.40.30.4-0.4-0.20.30.30.20.20.1
Number of responses in last shaping day1.61.74.0-1.3-1.3-0.8-1.7-0.00.20.4-1.9-2.00.62.0-1.21.2-1.9-1.1-1.1-1.1-1.0-1.4