Tsku

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_063262800.1 0.03 0.02 6.5e-03 0 0.01 0 0 1.4e-01 5.8e-02 1.6e-01 8.7e-02
2 Liver isoform ratio XM_063262800.1 0.41 0.13 0.0e+00 0.24 0.23 0.24 0.24 1.1e-26 1.6e-25 7.1e-26 7.4e-26
3 Liver intron excision ratio chr1_162073898_162081503 0.21 0.1 1.4e-14 0.1 0.1 0.11 0.11 1.0e-11 2.4e-11 8.0e-12 2.1e-12
4 Liver intron excision ratio chr1_162073898_162082536 0.11 0.06 7.3e-11 0.04 0.08 0.08 0.07 6.4e-05 3.9e-09 6.5e-09 9.5e-09
5 Adipose alternative TSS XM_006229761.5 0.05 0.03 1.3e-05 0.04 0.03 0.03 0.03 2.3e-05 2.3e-04 7.1e-04 1.2e-04
6 Adipose mRNA stability Tsku 0.09 0.06 2.4e-06 0.05 0.05 0.05 0.04 2.9e-06 5.1e-06 4.2e-06 1.5e-05
7 Liver isoform ratio XM_039113208.2 0.06 0.06 1.1e-03 0.03 0.01 0.02 0.03 2.8e-04 1.0e-02 3.0e-03 5.7e-04
8 Liver intron excision ratio chr1_162073898_162082718 0.12 0.07 2.6e-09 0.08 0.06 0.06 0.07 2.8e-09 6.8e-07 4.1e-07 2.5e-08
9 Liver intron excision ratio chr1_162073898_162082635 0.31 0.14 6.3e-07 0.03 0.03 0.03 0.03 4.0e-04 2.1e-04 2.1e-04 1.1e-04
10 Adipose isoform ratio XM_006229761.5 0.03 0.02 2.6e-03 0.02 0.01 0.01 0.01 1.0e-03 1.8e-02 2.7e-02 8.6e-03
11 PL gene expression Tsku 0.05 0.06 6.3e-03 0.02 0.01 0.01 0.01 5.5e-03 4.8e-02 5.4e-02 6.7e-02
12 Liver alternative TSS XM_039113208.2 0.34 0.11 5.6e-17 0.11 0.12 0.12 0.12 6.5e-12 3.7e-13 2.3e-13 5.8e-13
13 Liver alternative TSS XM_006229761.5 0.67 0.13 3.0e-08 0.03 0.06 0.07 0.05 1.6e-04 2.6e-07 5.1e-08 2.6e-06
14 Adipose gene expression Tsku 0.76 0.07 0.0e+00 0.48 0.53 0.54 0.52 5.2e-60 2.2e-69 3.3e-70 4.3e-68
15 Liver alternative TSS NM_001009965.3 0.55 0.13 1.4e-10 0.04 0.07 0.07 0.04 8.9e-05 6.3e-08 2.1e-08 2.0e-05
16 Liver isoform ratio NM_001009965.3 0.4 0.16 2.8e-05 0 0.01 0.01 0 1.3e-01 1.2e-02 8.2e-03 1.6e-01
17 Adipose intron excision ratio chr1_162073898_162082718 0.06 0.04 1.8e-04 0.01 0.02 0.01 0.02 2.3e-02 2.9e-03 8.5e-03 5.8e-03
18 Adipose alternative TSS XM_039113213.2 0.06 0.05 1.5e-03 0.02 0.01 0.02 0.01 6.3e-03 2.5e-02 2.2e-03 2.0e-02
19 Liver gene expression Tsku 0.28 0.13 4.2e-06 0.02 0.04 0.03 0.03 3.2e-03 2.7e-05 1.1e-04 6.6e-04
20 Adipose isoform ratio XM_039113213.2 0.08 0.06 2.3e-04 0.02 0.02 0.03 0.02 4.8e-03 4.1e-03 2.0e-04 5.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.20.30.7-0.4-0.30.2-0.4-0.70.8-0.8-0.80.1-0.80.4-0.50.7-0.80.4-0.3-0.1-0.7-0.3-0.7
Area under the delay curve0.10.10.60.4-0.00.00.30.2-0.20.20.20.00.1-0.40.1-0.80.10.6-0.2-0.00.20.10.1
BMI with tail0.82.812.6-0.2-0.40.4-1.10.6-0.40.40.4-1.50.11.91.72.71.0-3.52.62.01.6-2.81.7
BMI without tail0.84.415.20.3-1.31.3-0.61.4-1.21.31.3-2.30.62.32.52.51.9-3.93.03.02.2-2.82.3
Body weight1.25.123.30.3-1.01.1-0.81.3-1.11.01.0-2.30.42.12.73.31.6-4.83.82.82.1-3.22.1
Weight adjusted by age0.30.92.50.5-0.70.60.00.6-0.70.70.7-1.00.80.41.10.11.0-1.31.01.31.5-1.01.6
Bone surface0.91.85.01.7-2.22.21.41.6-1.21.21.2-1.91.2-0.81.5-0.51.1-0.71.21.40.9-0.50.8
Bone volume0.50.92.61.0-1.61.60.60.9-0.70.70.7-1.40.70.01.1-0.20.8-0.60.91.41.0-0.91.0
Breakpoint value in progressive ratio session0.71.21.9-1.11.4-1.3-0.9-1.11.1-1.1-1.11.4-1.30.3-1.30.5-1.21.1-0.9-1.2-1.30.3-1.2
Number of licking bursts1.23.56.5-2.32.1-2.0-2.6-2.22.2-2.2-2.21.6-2.22.4-1.42.5-2.0-0.2-0.4-0.8-0.9-1.7-0.7
Context. condit. distance diff. score1.11.43.11.6-1.71.71.51.1-1.11.11.1-1.21.3-1.70.9-1.70.80.20.40.40.60.20.5
Locomotion velocity, session 10.91.05.7-0.31.2-1.2-0.0-0.40.3-0.3-0.31.3-0.0-0.3-1.1-1.9-0.32.4-1.7-1.0-0.21.1-0.2
Locomotion distance, session 10.30.41.50.7-0.0-0.00.90.6-0.80.80.8-0.10.7-1.20.2-0.50.6-0.20.1-0.6-0.31.1-0.4
Locomotion velocity, session 20.40.52.80.50.2-0.20.50.7-0.70.70.70.10.90.00.2-1.70.80.7-0.40.51.00.41.0
Locomotion distance, session 20.20.30.70.5-0.10.10.70.7-0.80.80.8-0.20.8-0.40.4-0.40.8-0.30.10.10.30.90.2
Locomotion velocity, session 30.20.21.20.4-0.20.10.50.4-0.40.40.4-0.10.6-0.60.1-1.10.30.3-0.3-0.10.30.40.3
Locomotion distance, session 30.40.52.40.7-0.30.20.80.5-0.60.60.6-0.00.7-1.3-0.0-1.50.50.9-0.4-0.50.10.80.0
Stereotopy head waving bouts, day 30.30.30.9-0.90.6-0.6-0.7-0.60.3-0.3-0.30.5-0.70.8-0.40.9-0.2-0.3-0.4-0.1-0.60.2-0.5
Stereotopy head waving duration, day 30.20.21.00.4-0.50.60.70.4-0.60.60.6-0.20.3-0.50.2-0.50.50.1-0.2-0.0-0.31.0-0.4
Locomotion velocity, session 70.30.40.8-0.50.6-0.7-0.7-0.60.8-0.8-0.80.6-0.30.4-0.6-0.4-0.70.9-0.6-0.20.4-0.60.5
Locomotion distance, session 70.20.21.5-0.00.2-0.3-0.5-0.20.1-0.1-0.1-0.20.10.50.30.2-0.1-0.40.60.40.7-1.20.7
Stereotopy head waving bouts, day 71.01.23.91.1-1.01.01.61.0-1.01.01.0-0.30.9-1.80.1-1.80.71.1-0.7-0.4-0.32.0-0.5
Stereotopy head waving duration, day 71.41.73.61.6-1.61.61.91.6-1.51.51.5-1.01.4-1.70.9-1.71.20.20.10.30.21.50.0
Locomotion velocity, session 81.31.67.31.6-1.51.51.50.9-1.01.01.0-0.81.3-1.60.7-2.70.81.5-0.40.60.90.20.8
Locomotion distance, session 81.11.53.21.6-1.31.31.61.3-1.51.51.5-1.01.6-1.71.0-1.81.2-0.00.30.40.70.80.6
Degree of sensitization distance0.80.93.4-0.1-0.30.3-0.60.10.0-0.0-0.0-0.8-0.01.31.01.50.1-1.81.41.30.8-1.70.8
Degree of sensitization stereotypy2.12.47.21.9-1.61.62.31.7-1.51.51.5-0.91.6-2.70.6-2.31.10.8-0.2-0.2-0.02.1-0.2
Conditioned locomotion0.20.31.4-0.30.4-0.3-0.0-0.20.3-0.3-0.30.6-0.2-0.2-0.7-0.7-0.21.2-1.0-0.5-0.30.6-0.2
Cocaine response after cond. corrected0.50.82.8-0.81.3-1.2-1.3-0.80.9-0.9-0.90.6-0.61.1-0.41.1-0.8-0.30.5-0.00.5-1.70.6
Cocaine response after cond. not corrected0.20.30.7-0.30.9-0.8-0.6-0.40.5-0.5-0.50.4-0.40.2-0.20.9-0.6-0.30.5-0.5-0.1-0.8-0.1
Cocaine response before conditioning0.80.94.40.8-0.70.71.30.6-0.70.70.7-0.20.3-1.60.1-0.70.30.3-0.5-0.9-1.32.1-1.5
Saline control response1.52.13.41.7-1.41.51.61.8-1.71.71.7-1.61.5-1.11.7-0.21.5-1.81.70.90.70.60.5
Bone: connectivity density0.20.31.30.2-0.70.60.3-0.10.4-0.4-0.4-0.0-0.4-0.4-0.4-0.3-0.61.1-0.5-0.2-0.70.3-0.7
Bone: cortical apparent density0.60.91.7-1.21.2-1.1-1.3-1.21.1-1.1-1.11.0-1.11.2-0.90.9-1.00.5-0.5-0.3-0.4-0.7-0.3
Bone: cortical area1.01.66.40.8-1.41.50.20.9-0.50.50.5-1.70.40.21.51.60.6-2.52.21.30.9-1.70.8
Bone: cortical porosity0.40.42.30.5-0.20.20.90.4-0.50.50.5-0.00.4-1.30.1-0.50.2-0.0-0.2-0.8-0.81.5-0.9
Bone: cortical porosity0.50.53.00.5-0.10.11.00.4-0.50.50.50.10.4-1.2-0.1-0.90.30.5-0.6-0.8-0.61.7-0.8
Bone: cortical thickness0.50.84.0-0.80.4-0.3-1.1-0.81.0-1.0-1.00.1-1.10.7-0.22.0-1.0-1.30.8-0.2-0.4-1.4-0.3
Bone: cortical thickness0.20.21.50.3-0.10.1-0.00.1-0.20.20.2-0.50.2-0.10.60.40.1-1.21.10.20.4-0.80.3
Bone: cortical tissue density0.61.01.6-1.31.3-1.2-1.3-1.31.1-1.1-1.11.1-1.11.1-1.00.7-1.00.7-0.7-0.4-0.5-0.5-0.4
Condit. Reinf. active minus inactive responses0.60.62.30.2-0.60.6-0.30.2-0.20.20.2-0.90.10.50.91.10.4-1.51.41.10.7-1.40.8
Condit. Reinf. active-inactive response ratio0.80.92.60.6-1.31.20.20.6-0.50.50.5-1.40.40.21.20.90.6-1.61.51.20.6-1.10.6
Condit. Reinf. active responses0.20.31.1-0.3-0.0-0.0-0.6-0.20.2-0.2-0.2-0.3-0.20.60.30.80.0-0.80.70.60.5-1.10.6
Condit. Reinf. inactive responses0.20.20.6-0.50.8-0.7-0.5-0.50.5-0.4-0.40.6-0.20.3-0.5-0.1-0.30.5-0.5-0.20.2-0.10.3
Incentive salience index mean0.40.51.80.1-0.40.4-0.30.1-0.10.10.1-0.70.30.60.70.30.4-0.90.91.11.1-1.41.2
Condit. Reinf. lever presses0.20.31.40.1-0.10.1-0.1-0.0-0.00.00.0-0.00.50.30.0-1.20.30.7-0.40.51.0-0.41.1
Condit. Reinf. active minus inactive responses5.48.412.03.4-3.33.32.93.4-3.23.23.2-3.53.2-2.33.4-0.73.0-3.33.12.22.2-0.11.9
Condit. Reinf. active-inactive response ratio0.81.32.51.2-1.01.00.81.2-1.11.11.1-1.31.4-0.71.3-0.21.1-1.61.51.01.4-0.71.3
Condit. Reinf. active responses9.413.519.54.2-4.24.13.64.4-4.14.24.2-4.44.0-2.74.4-0.93.9-3.94.03.02.8-0.02.4
Condit. Reinf. inactive responses4.97.210.83.0-3.23.12.93.2-3.33.33.3-3.12.9-1.93.2-1.13.2-2.22.32.21.80.71.5
Condit. Reinf. lever presses15.322.235.96.0-5.75.85.75.8-5.55.55.5-5.25.4-4.95.0-2.94.8-3.13.82.82.71.72.1
Condit. Reinf. lever reinforcers received10.314.420.74.4-4.44.33.84.6-4.34.34.3-4.54.2-3.04.5-1.04.0-4.04.13.02.90.12.5
Conditioned reinforcement - actives0.20.82.21.3-1.11.11.41.0-1.01.01.0-0.80.7-1.50.7-1.20.80.20.30.20.20.80.0
Conditioned reinforcement - inactives0.20.72.3-0.50.5-0.6-0.1-0.80.8-0.8-0.80.9-0.6-0.3-1.1-0.8-0.91.5-1.3-1.0-0.60.9-0.6
Conditioned locomotion0.91.34.31.4-0.60.71.81.1-1.11.11.1-0.31.0-2.10.4-2.00.70.7-0.4-0.6-0.01.8-0.2
Patch foraging indifference point 0 sec2.26.110.93.2-3.33.23.22.9-2.92.82.8-2.82.5-2.72.6-1.22.4-1.92.11.40.81.20.5
Patch foraging indifference point AUC0.10.30.80.4-0.70.70.10.4-0.40.40.4-0.70.40.10.7-0.20.6-0.40.60.90.8-0.80.8
Delay disc. indifference point, 0s delay1.01.11.91.2-0.80.81.11.4-1.41.41.4-1.01.2-1.01.2-0.71.3-0.71.00.80.80.30.7
Delay disc. indifference point, 16s delay0.20.31.3-0.10.5-0.4-0.0-0.40.4-0.4-0.40.6-0.3-0.3-0.6-0.8-0.51.2-0.9-0.5-0.20.2-0.2
Delay disc. indifference point, 2s delay0.91.11.91.3-0.90.91.41.3-1.31.31.3-0.91.2-1.20.9-1.11.1-0.50.60.30.60.80.5
Delay disc. indifference point, 24s delay0.50.91.4-1.11.0-1.0-1.2-1.11.1-1.1-1.10.9-1.11.2-0.90.5-1.00.9-0.7-0.4-0.4-0.9-0.2
Delay disc. indifference point, 4s delay1.41.52.71.3-0.50.60.91.5-1.51.51.5-1.01.3-0.41.4-1.01.6-0.71.11.21.6-0.41.6
Delay disc. indifference point, 8s delay0.10.10.50.5-0.60.50.50.2-0.20.20.2-0.2-0.1-0.60.2-0.70.10.6-0.20.1-0.10.1-0.1
Indifference point function ln k0.30.93.31.1-0.70.71.51.0-0.90.90.9-0.30.7-1.70.3-1.20.50.4-0.2-0.6-0.51.8-0.7
Indifference point function log k0.30.93.31.1-0.70.71.51.0-0.90.90.9-0.30.7-1.70.3-1.20.50.4-0.2-0.6-0.51.8-0.7
Patch foraging total patch changes 0 sec1.85.29.63.0-3.13.02.92.7-2.72.62.6-2.72.2-2.52.5-1.22.2-1.72.01.30.81.10.4
Patch foraging total patch changes 12 sec1.62.24.21.5-2.12.01.21.5-1.51.51.5-2.01.2-0.51.8-0.31.5-1.61.71.71.3-0.61.2
Patch foraging total patch changes 18 sec1.63.76.02.1-2.42.41.82.2-2.22.12.1-2.31.9-0.82.3-1.02.2-1.41.72.11.8-0.31.6
Patch foraging total patch changes 24 sec0.31.11.81.0-1.01.00.81.3-1.31.21.2-1.21.0-0.31.3-0.21.3-1.31.31.11.0-0.30.9
Patch foraging total patch changes 6 sec0.81.44.01.5-2.01.81.61.2-1.11.01.0-1.50.7-1.81.2-0.20.7-0.91.10.3-0.30.6-0.5
Patch foraging time to switch 0 sec1.45.58.6-2.92.9-2.8-2.7-2.82.8-2.8-2.82.7-2.61.9-2.61.5-2.51.7-2.0-1.8-1.5-0.3-1.3
Patch foraging water rate 0 sec1.34.77.72.8-2.62.52.62.7-2.72.72.7-2.42.3-2.02.3-1.42.4-1.31.91.41.20.70.9
Patch foraging water rate 12 sec0.62.34.21.9-1.61.72.02.0-2.01.91.9-1.31.7-1.41.2-1.71.8-0.10.60.70.61.30.4
Patch foraging water rate 18 sec0.41.01.91.1-1.11.01.01.4-1.21.21.2-1.01.2-0.40.9-1.21.2-0.10.61.01.00.10.9
Patch foraging water rate 24 sec0.60.83.11.0-0.80.81.30.9-0.90.90.9-0.30.8-1.40.1-1.80.71.0-0.4-0.20.01.1-0.1
Patch foraging water rate 6 sec0.40.51.70.9-0.80.91.10.6-0.70.70.7-0.40.6-1.10.2-1.30.50.7-0.3-0.1-0.11.0-0.2
Seeking ratio, delayed vs. immediate footshock1.31.83.3-1.61.7-1.7-1.8-1.61.6-1.6-1.61.4-1.41.5-1.40.6-1.31.1-1.0-0.6-0.2-1.1-0.0
Distance traveled before self-admin0.20.50.7-0.80.7-0.8-0.7-0.80.8-0.8-0.80.7-0.70.5-0.70.7-0.80.4-0.6-0.4-0.6-0.3-0.5
Distance traveled after self-admin1.32.43.9-1.51.8-1.8-0.9-1.51.5-1.5-1.51.9-1.40.1-1.90.5-1.61.4-1.7-2.0-1.91.2-1.8
Extensor digitorum longus weight0.31.25.90.0-0.50.5-0.80.4-0.0-0.0-0.0-1.00.21.51.00.90.3-1.31.51.71.6-2.41.7
Bone: elastic displacement1.31.62.9-1.31.2-1.3-1.3-1.51.7-1.7-1.71.3-1.40.8-1.30.8-1.70.9-0.7-1.0-1.0-0.6-0.9
Bone: elastic work2.02.74.8-1.61.5-1.5-1.5-1.82.1-2.1-2.11.8-1.90.6-1.90.8-2.21.5-1.3-1.5-1.5-0.3-1.4
Bone: endosteal estimation1.43.56.01.8-2.22.11.22.1-1.81.81.8-2.31.9-0.12.2-0.42.1-1.61.92.52.2-1.12.1
Bone: endosteal perimeter2.25.47.92.4-2.82.82.02.6-2.62.62.6-2.72.6-0.72.5-1.52.8-1.31.72.62.6-0.62.5
Epididymis fat weight0.31.68.2-1.20.9-0.9-1.7-0.70.9-0.9-0.90.1-1.21.80.12.9-0.5-2.01.20.40.1-2.00.2
Delta time in closed arm before/after self-admin0.60.53.0-0.60.3-0.3-1.1-0.60.6-0.6-0.60.1-0.31.4-0.10.4-0.30.10.10.80.8-1.71.0
Delta time in open arm before/after self-admin2.22.64.41.9-2.12.01.71.8-1.81.81.8-1.91.9-1.01.8-0.71.7-1.21.61.51.20.01.0
Diff in mean of infusions in LGA sessions3.15.68.9-2.93.0-3.0-2.8-2.72.7-2.7-2.72.6-2.72.1-2.52.1-2.41.2-1.6-1.8-1.9-0.7-1.6
Delay discount exponential model param0.10.10.6-0.4-0.00.0-0.3-0.20.2-0.2-0.2-0.1-0.00.3-0.00.7-0.1-0.60.20.1-0.1-0.2-0.1
Extinction: sum of active levers before priming0.20.30.60.40.10.00.20.5-0.60.60.6-0.30.40.30.70.10.6-0.80.80.70.6-0.40.6
Active lever presses in extinction session 61.71.79.11.0-0.40.41.90.7-0.70.70.70.20.1-2.6-0.3-1.20.10.8-0.7-1.5-1.63.0-1.9
Bone: final force0.20.31.60.1-0.50.6-0.1-0.10.5-0.5-0.5-0.3-0.5-0.40.11.2-0.7-0.60.7-0.2-0.7-0.8-0.7
Bone: final moment0.20.31.40.3-0.70.80.10.10.2-0.2-0.2-0.5-0.3-0.40.31.2-0.4-0.80.9-0.0-0.5-0.7-0.6
Food consumed during 24 hour testing period1.53.011.81.8-1.41.42.31.7-1.91.91.9-0.71.8-2.10.5-3.41.81.8-1.10.30.52.40.3
Glucose0.10.21.10.2-0.0-0.0-0.20.2-0.20.20.2-0.30.40.30.5-0.20.4-0.40.50.60.9-1.00.9
Heart weight0.40.72.01.0-1.41.31.00.8-0.80.70.7-1.10.4-1.00.90.20.5-0.90.90.4-0.10.1-0.3
Delay discount hyperbolic model param0.10.20.7-0.50.2-0.2-0.4-0.50.5-0.5-0.50.2-0.30.3-0.30.8-0.4-0.3-0.1-0.2-0.4-0.0-0.4
Intermittent access intake day 1-15 change0.21.34.51.5-1.21.21.91.2-1.21.21.2-0.61.2-2.10.6-1.40.70.3-0.2-0.2-0.41.7-0.6
Intermittent access intake escalation0.31.55.01.7-1.31.32.01.2-1.21.21.2-0.71.2-2.20.7-1.30.70.2-0.1-0.2-0.41.6-0.7
Intermittent access intake escalation 20.50.92.61.3-1.31.21.51.0-1.01.01.0-0.80.8-1.60.6-1.10.60.1-0.10.0-0.11.1-0.3
Intermitt. access day 1 inactive lever presses0.22.63.9-1.91.8-1.9-1.6-1.91.9-1.9-1.91.9-1.61.1-2.00.2-1.91.5-1.9-1.4-0.80.1-0.6
Intermitt. access day 15 inactive lever presses0.52.63.8-1.91.9-1.9-1.6-1.91.9-1.9-1.91.9-1.70.9-1.90.6-1.91.1-1.7-1.6-1.00.1-0.9
Intermitt. access escalation Index0.10.30.7-0.40.1-0.2-0.3-0.70.7-0.7-0.70.5-0.2-0.0-0.80.2-0.70.8-0.5-0.6-0.80.2-0.8
Intermittent access day 1 total infusions0.20.61.61.0-1.11.00.90.7-0.70.70.7-0.70.8-1.00.5-1.30.60.50.10.40.50.30.4
Intermittent access day 15 total infusions0.71.74.71.8-1.51.42.01.3-1.31.31.3-0.81.4-2.20.7-2.10.80.8-0.20.00.11.4-0.1
Intermittent access terminal intake (last 3 days)1.11.84.51.8-1.81.81.91.3-1.31.31.3-1.21.3-2.01.0-2.11.00.3-0.00.40.71.00.5
Intermittent access total infusions1.01.22.61.4-1.61.51.41.1-1.11.11.1-1.21.2-1.31.0-1.61.00.20.40.80.90.20.8
Intermittent access day 1 locomotion0.10.20.90.3-0.50.40.4-0.10.1-0.1-0.1-0.00.2-0.6-0.3-0.9-0.21.0-0.5-0.3-0.10.5-0.1
Intermittent access day 15 total locomotion0.31.23.91.4-1.11.11.71.0-1.01.01.0-0.61.3-2.00.5-1.70.70.5-0.2-0.30.01.7-0.1
Intermittent access total locomotion0.60.71.51.1-1.11.11.20.8-0.80.80.8-0.80.9-1.10.6-1.20.60.20.10.30.50.70.4
Intermittent access standard deviation0.10.81.40.7-1.11.00.40.9-0.90.90.9-1.20.70.31.1-0.11.0-1.00.81.21.1-0.61.0
Left kidney weight0.32.45.90.6-0.80.90.11.4-1.41.41.4-1.61.11.21.90.81.9-2.42.02.22.0-1.22.0
Right kidney weight0.43.16.60.9-1.21.30.31.6-1.61.71.7-2.01.61.12.20.52.1-2.52.22.62.4-1.32.3
Cocaine induced anxiety0.61.52.8-1.61.3-1.3-1.7-1.51.5-1.5-1.51.1-1.51.4-1.01.4-1.20.1-0.9-0.5-0.6-0.8-0.4
Post-drug Anxiety1.11.32.2-1.41.3-1.2-1.5-1.41.4-1.4-1.41.1-1.41.3-1.00.9-1.20.5-0.9-0.4-0.5-0.9-0.3
Baseline Anxiety0.20.31.20.7-0.50.60.60.5-0.50.50.5-0.40.7-0.40.4-1.10.50.40.10.50.6-0.10.6
Tail length1.05.112.51.1-1.81.80.32.0-2.02.02.0-2.61.72.02.80.92.5-3.02.83.52.9-2.22.8
Length with tail0.83.713.10.8-1.31.3-0.01.5-1.41.31.3-2.21.11.52.51.91.8-3.63.02.62.0-2.12.0
Length without tail0.10.52.2-0.70.9-0.8-0.7-0.50.5-0.5-0.50.4-0.80.4-0.11.5-0.5-1.10.5-0.5-0.7-0.2-0.6
Times rat made contact with spout0.20.21.5-0.50.3-0.2-0.6-0.40.2-0.2-0.20.1-0.21.2-0.00.20.1-0.0-0.30.70.4-0.50.5
Lifetime Intake1.11.43.41.5-1.71.61.51.2-1.21.21.2-1.21.2-1.50.9-1.91.00.40.20.60.70.50.6
Liver weight, left0.50.83.9-0.10.2-0.1-0.60.4-0.40.30.3-0.60.11.40.81.40.5-2.01.61.10.8-1.30.8
Liver weight, right1.11.97.1-1.01.0-1.0-1.70.00.2-0.1-0.1-0.2-0.52.70.82.30.4-2.31.51.51.3-2.31.4
Locomotor activity0.81.22.41.0-1.31.21.31.1-1.51.51.5-1.11.1-0.71.0-0.81.5-0.50.20.90.61.30.5
Locomotor testing distance1.43.45.61.8-1.91.91.62.1-2.22.22.2-2.21.8-0.32.2-0.42.4-2.01.82.01.80.11.6
Locomotor testing rearing0.51.85.60.8-1.21.20.41.3-1.31.31.3-1.60.70.81.80.81.5-2.41.81.81.2-0.81.2
Locomotion in novel chamber0.40.61.61.0-0.60.71.20.9-0.90.90.9-0.30.8-1.20.3-1.10.50.5-0.1-0.2-0.11.1-0.3
Locomotion in novel chamber post-restriction0.72.26.02.0-1.31.42.41.7-1.71.71.7-0.91.3-2.50.9-1.91.00.10.3-0.1-0.31.9-0.6
Fecal boli incidents, locomotor time 10.20.42.10.9-0.50.51.00.5-0.50.50.5-0.20.7-1.10.2-1.50.30.6-0.2-0.00.30.60.2
Change in fecal boli incidents, locomotor task0.70.71.2-1.11.0-1.0-0.8-0.70.8-0.8-0.80.9-1.10.7-0.80.8-0.80.4-0.8-0.8-1.10.3-1.1
Time >=10cm from walls, locomotor time 10.81.02.81.3-1.01.01.61.0-1.01.01.0-0.51.0-1.70.4-1.30.60.40.2-0.3-0.31.4-0.5
Bouts of movement, locomotor time 10.10.10.30.40.1-0.10.30.5-0.50.50.5-0.10.4-0.40.4-0.30.4-0.40.10.20.3-0.00.3
Total resting periods, locomotor time 10.10.10.20.10.5-0.50.10.1-0.10.10.10.4-0.0-0.5-0.2-0.3-0.10.1-0.3-0.4-0.20.2-0.3
Rest time, locomotor task time 10.30.51.4-0.41.1-1.2-0.2-0.30.3-0.3-0.31.0-0.6-0.1-0.8-0.3-0.60.9-0.8-1.0-1.00.5-1.0
Distance moved, locomotor task time 10.51.33.40.7-1.31.40.30.7-0.70.70.7-1.40.90.51.3-0.11.1-1.21.11.71.8-1.21.8
Vertical activity count, locomotor time 10.21.22.81.0-1.71.70.60.8-0.80.80.8-1.60.9-0.11.30.11.0-1.11.01.41.3-0.91.3
Time >=10cm from walls, locomotor time 20.41.12.41.2-0.90.81.11.5-1.41.41.4-1.01.2-0.81.3-0.61.3-1.01.10.70.70.20.5
Bouts of movement, locomotor time 20.31.01.91.1-0.70.61.01.4-1.31.31.3-0.91.1-0.61.1-0.81.2-1.20.60.70.80.50.7
Total resting periods, locomotor time 20.10.51.10.8-0.30.30.81.0-1.01.01.0-0.60.8-0.50.8-0.70.9-0.90.30.40.60.50.5
Rest time, locomotor task time 21.32.23.6-1.71.6-1.6-1.5-1.71.6-1.6-1.61.6-1.91.4-1.61.5-1.50.8-0.9-1.1-1.6-0.3-1.4
Distance moved, locomotor task time 22.53.34.62.0-1.91.81.62.2-2.02.02.0-2.02.1-1.02.1-1.32.0-1.31.61.72.1-0.21.9
Vertical activity count, locomotor time 21.02.24.21.4-1.81.71.01.6-1.41.41.4-1.81.6-0.41.8-0.91.5-1.31.11.72.1-0.82.0
Light reinforcement 10.41.64.4-1.61.5-1.5-1.7-1.41.5-1.5-1.51.0-1.31.4-0.92.1-1.3-0.50.1-0.6-0.7-1.0-0.5
Light reinforcement 20.10.20.6-0.10.4-0.40.10.00.2-0.1-0.10.3-0.0-0.5-0.20.8-0.3-0.40.3-0.7-0.70.7-0.8
Bone: marrow area1.33.15.61.6-2.12.01.12.0-1.71.71.7-2.21.80.02.1-0.31.9-1.51.82.42.1-1.12.0
Bone: maximum diameter2.24.48.22.2-2.82.91.72.4-2.12.12.1-2.81.9-0.92.5-0.12.1-2.52.52.11.7-0.81.5
Bone: maximum force0.20.31.10.3-0.70.80.2-0.00.5-0.5-0.5-0.3-0.5-0.70.11.0-0.7-0.40.6-0.3-0.7-0.6-0.8
Bone: maximum moment0.20.30.90.5-0.91.00.30.20.2-0.2-0.2-0.6-0.2-0.70.30.9-0.4-0.60.8-0.1-0.6-0.5-0.6
Mean time between licks in bursts1.05.99.22.4-2.52.42.12.9-2.92.92.9-2.72.9-1.02.8-1.53.0-2.11.92.52.70.12.5
Mean num. licks in bursts1.23.25.52.2-2.12.02.32.0-2.12.12.1-1.62.1-1.81.5-2.32.00.00.41.11.21.21.0
Cd content in liver0.60.73.0-0.60.5-0.4-1.1-0.30.5-0.6-0.6-0.1-0.31.30.21.4-0.3-1.11.00.60.7-1.70.8
Co content in liver1.11.32.71.0-1.11.20.70.9-1.11.21.2-1.21.40.11.2-1.01.3-0.60.91.51.6-0.51.6
Cu content in liver0.91.03.10.3-0.30.3-0.10.8-0.91.01.0-0.90.91.01.2-0.11.3-1.20.91.61.7-1.01.7
Fe content in liver0.00.10.2-0.00.3-0.2-0.20.20.3-0.3-0.30.1-0.20.0-0.00.4-0.3-0.20.4-0.10.1-0.50.1
K content in liver0.20.21.2-0.50.2-0.2-0.2-0.20.3-0.2-0.20.4-0.20.3-0.6-0.6-0.00.8-1.1-0.1-0.00.60.1
Mg content in liver0.20.21.00.2-0.10.10.50.4-0.30.40.40.00.4-0.5-0.1-1.00.40.5-0.6-0.20.10.90.1
Mn content in liver1.61.83.3-1.21.5-1.4-0.7-1.21.2-1.2-1.21.7-1.3-0.2-1.7-0.1-1.41.7-1.8-1.8-1.61.1-1.6
Na content in liver0.50.52.90.8-0.60.61.20.5-0.60.60.6-0.20.5-1.30.1-0.80.30.3-0.3-0.6-0.51.7-0.6
Rb content in liver0.10.20.60.2-0.80.60.10.4-0.20.30.3-0.60.20.10.4-0.10.4-0.30.00.50.3-0.40.4
Se content in liver5.46.411.3-2.93.4-3.2-2.6-2.53.0-3.0-3.03.1-2.81.5-2.91.5-2.91.9-2.0-2.3-1.9-0.1-1.7
Sr content in liver0.10.00.20.3-0.20.20.30.20.0-0.0-0.0-0.00.1-0.4-0.0-0.4-0.20.30.0-0.2-0.20.2-0.2
Zn content in liver2.83.25.11.7-1.81.71.32.0-2.02.12.1-2.02.1-0.72.1-1.32.3-1.41.31.92.2-0.32.1
Bone: minimum diameter1.32.45.70.8-1.51.60.11.1-1.01.01.0-1.90.91.01.81.21.4-2.42.22.31.9-2.01.9
Time in familiar zone, hab. session 10.10.10.3-0.30.4-0.4-0.3-0.30.2-0.2-0.20.3-0.10.5-0.2-0.5-0.00.5-0.40.10.3-0.30.4
Time in novel zone, hab. session 10.20.21.6-0.1-0.20.2-0.30.00.1-0.1-0.1-0.4-0.20.30.41.3-0.1-1.10.80.30.0-0.70.0
Total zone transitions, hab. session 10.40.62.80.0-0.20.30.5-0.20.3-0.3-0.30.3-0.5-1.0-0.50.6-0.60.2-0.5-1.2-1.61.4-1.7
Total locomotion distance, hab. session 11.01.49.8-1.30.6-0.6-1.5-0.90.8-0.8-0.80.1-1.11.70.03.1-0.5-2.30.80.3-0.4-1.1-0.3
Locomotion velocity, hab. session 10.81.18.3-1.10.4-0.4-1.2-0.70.7-0.7-0.7-0.1-1.01.30.12.9-0.4-2.20.80.2-0.5-0.8-0.4
Time in familiar zone, hab. session 21.31.53.11.1-1.51.51.01.1-1.41.41.4-1.31.2-0.51.2-1.81.5-0.10.11.41.4-0.11.3
Time in novel zone, hab. session 20.30.31.3-0.30.9-0.9-0.4-0.20.6-0.6-0.60.6-0.40.2-0.41.1-0.7-0.50.6-0.7-0.4-0.1-0.4
Total zone transitions, hab. session 20.70.93.80.9-0.80.71.30.7-0.50.50.5-0.40.4-2.00.20.60.1-0.80.5-1.0-1.21.7-1.4
Total locomotion distance, hab. session 20.81.07.9-0.5-0.00.1-0.7-0.10.2-0.2-0.2-0.6-0.40.80.52.8-0.1-2.71.50.4-0.1-0.7-0.1
Locomotion velocity, hab. session 20.91.28.9-0.60.0-0.0-0.8-0.20.2-0.2-0.2-0.6-0.51.00.53.0-0.0-2.81.60.5-0.1-0.8-0.1
Novel to familiar place preference ratio0.20.20.90.3-0.10.00.30.3-0.10.10.1-0.20.0-0.60.20.9-0.1-0.70.8-0.4-0.60.4-0.7
Novelty place preference0.10.10.50.20.1-0.10.20.3-0.20.20.2-0.10.1-0.40.10.6-0.0-0.60.7-0.3-0.30.3-0.4
Time in novel zone, NPP test0.10.10.50.4-0.10.10.40.4-0.30.30.3-0.30.3-0.60.30.40.1-0.50.7-0.2-0.20.3-0.2
Total zone transitions, NPP test0.20.31.10.10.2-0.20.4-0.20.1-0.1-0.10.4-0.2-1.1-0.40.2-0.30.3-0.3-1.0-0.90.9-1.0
Total locomotion distance, NPP test1.01.48.3-1.21.1-1.1-1.5-0.70.8-0.8-0.80.2-0.91.2-0.12.9-0.5-2.21.1-0.0-0.1-1.2-0.0
Locomotion velocity, NPP test1.31.810.7-1.51.4-1.4-1.8-0.91.0-1.0-1.00.5-1.21.5-0.33.3-0.8-2.31.1-0.2-0.4-1.3-0.2
Intraocular pressure0.30.52.80.9-0.50.50.90.4-0.20.20.2-0.10.7-1.5-0.1-1.7-0.01.5-0.4-0.20.50.20.4
Delta distance traveled before/after self-admin0.50.53.70.3-0.00.10.80.1-0.20.20.20.30.1-1.2-0.3-0.8-0.10.5-0.7-1.0-0.91.9-1.0
Delta ambulatory time before/after self-admin0.30.53.40.30.00.00.80.1-0.10.10.10.40.1-1.3-0.4-0.8-0.20.6-0.7-1.1-0.91.8-1.0
Parametrial fat weight0.51.29.4-0.80.5-0.4-0.9-0.30.6-0.6-0.60.1-1.30.80.03.1-0.6-1.71.2-0.3-1.3-0.7-1.3
Pavlov. Cond. lever latency0.91.14.0-1.11.1-1.1-1.0-1.01.1-1.1-1.10.9-1.30.5-0.92.0-1.1-0.30.1-1.1-1.3-0.0-1.2
Pavlov. Cond. magazine entry latency2.32.94.82.1-2.22.21.82.0-1.81.81.8-2.01.9-1.22.0-1.01.7-1.41.51.51.4-0.11.3
Pavlov. Cond. change in total contacts0.60.61.21.0-0.70.70.70.9-0.70.70.7-0.71.0-0.60.8-1.10.7-0.20.50.61.1-0.31.0
Pavlov. Cond. index score1.92.43.51.7-1.81.81.41.6-1.71.71.7-1.71.8-0.71.7-1.71.7-0.70.81.71.9-0.31.7
Pavlov. Cond. latency score1.72.13.11.7-1.81.81.41.5-1.61.61.6-1.61.7-0.81.6-1.61.5-0.70.81.51.7-0.21.5
Pavlov. Cond. lever contacts0.80.92.90.9-0.90.90.70.8-0.90.90.9-0.81.2-0.10.8-1.71.10.1-0.01.21.5-0.21.4
Pavlov. Cond. magazine entry number2.43.04.5-2.12.1-2.1-1.7-1.91.9-1.9-1.92.1-2.01.1-2.01.1-1.81.4-1.5-1.6-1.70.2-1.6
Pavlov. Cond. intertrial magazine entries1.21.43.6-1.71.8-1.9-1.6-1.31.2-1.2-1.21.4-1.21.3-1.30.8-1.00.7-0.8-0.7-0.5-0.2-0.4
Pavlov. Cond. lever-magazine prob. diff.1.51.93.01.5-1.61.61.31.4-1.51.51.5-1.41.6-0.51.4-1.71.5-0.30.51.51.7-0.21.6
Pavlov. Cond. response bias0.81.01.81.1-1.11.10.81.0-1.01.01.0-1.01.1-0.41.0-1.31.1-0.20.31.11.3-0.31.3
Pavlov. Cond. lever latency15.822.237.4-6.15.6-5.7-5.9-5.85.5-5.5-5.55.1-5.55.1-4.83.6-4.82.5-3.6-2.6-2.7-2.0-2.1
Pavlov. Cond. magazine entry latency3.04.28.32.9-2.72.82.82.5-2.22.22.2-2.22.3-2.81.9-1.61.6-0.91.50.70.81.00.5
Pavlov. Cond. change in total contacts6.315.324.75.0-4.54.54.84.9-4.64.64.6-4.34.5-4.14.1-2.44.0-2.83.42.12.21.51.7
Pavlov. Cond. index score10.216.027.35.2-4.84.95.04.9-4.64.64.6-4.34.7-4.44.1-2.93.9-2.33.22.12.31.51.8
Pavlov. Cond. latency score8.513.724.04.9-4.54.64.74.6-4.34.34.3-4.04.3-4.33.7-2.83.6-1.92.81.82.01.61.6
Pavlov. Cond. lever contacts14.321.135.15.9-5.55.65.75.6-5.45.45.4-5.05.3-4.94.8-3.44.6-2.63.62.62.71.82.1
Pavlov. Cond. magazine entry number5.36.912.6-3.53.0-3.1-3.2-3.22.9-2.9-2.92.7-3.23.0-2.52.7-2.50.9-1.9-1.4-2.1-0.5-1.8
Pavlov. Cond. intertrial magazine entries0.30.62.30.1-0.50.5-0.10.3-0.60.60.6-0.90.30.81.00.90.9-1.51.01.30.7-0.60.7
Pavlov. Cond. lever-magazine prob. diff.9.815.025.65.1-4.74.74.84.8-4.54.54.5-4.24.5-4.24.0-2.83.8-2.33.22.12.41.41.9
Pavlov. Cond. response bias15.321.135.56.0-5.65.65.75.6-5.35.35.3-5.05.4-4.94.7-3.64.6-2.43.52.62.91.72.3
Time in closed arm before self-admin0.20.41.90.6-0.40.30.90.4-0.40.40.4-0.00.4-1.2-0.1-1.00.10.6-0.5-0.6-0.51.4-0.6
Time in closed arm after self-admin1.21.33.7-1.01.2-1.2-0.8-1.31.3-1.3-1.31.4-0.90.2-1.5-0.6-1.31.9-1.5-1.2-0.70.2-0.6
Time in open arm before self-admin1.31.63.0-1.71.6-1.6-1.7-1.51.4-1.4-1.41.3-1.61.3-1.21.4-1.20.1-0.7-0.8-0.7-0.8-0.5
Time in open arm after self-admin0.91.02.70.7-1.31.20.50.8-0.90.90.9-1.30.60.21.21.01.0-1.61.41.30.6-0.60.5
Bone: periosteal estimation1.63.76.81.8-2.32.31.02.0-1.61.61.6-2.51.6-0.02.40.41.8-2.42.62.42.1-1.72.0
Bone: periosteal perimeter1.73.46.01.8-2.42.51.41.8-1.91.91.9-2.31.7-0.32.1-0.52.1-1.71.72.21.9-0.81.8
Bone: post-yield work0.20.31.40.5-1.01.20.50.3-0.10.10.1-0.6-0.1-0.40.30.7-0.1-0.50.50.1-0.60.1-0.7
Progressive ratio test 1 active lever presses0.20.41.2-0.20.3-0.3-0.0-0.60.6-0.6-0.60.6-0.5-0.6-0.7-0.7-0.71.1-0.8-0.8-0.60.5-0.6
Progressive ratio test 1 breakpoint0.20.31.1-0.20.3-0.3-0.0-0.50.5-0.5-0.50.6-0.5-0.6-0.7-0.6-0.71.1-0.8-0.8-0.60.5-0.5
Progressive ratio test 1 inactive lever presses0.40.91.6-0.90.4-0.5-0.5-1.11.1-1.1-1.10.9-1.3-0.2-1.20.1-1.21.1-1.3-1.2-1.10.6-1.0
Progressive ratio test 2 active lever presses0.71.02.71.2-1.11.00.91.0-1.01.01.0-0.91.2-0.81.0-1.71.00.10.40.91.4-0.31.4
Progressive ratio test 2 breakpoint0.81.02.81.2-1.11.10.91.0-1.01.01.0-0.91.2-0.90.9-1.70.90.20.40.91.4-0.31.4
Progressive ratio test 2 inactive lever presses0.10.31.10.5-0.70.70.50.4-0.40.40.4-0.50.4-0.50.4-1.00.40.2-0.10.40.8-0.00.8
Incentive Sensitization - Responses0.82.13.51.7-1.71.71.41.5-1.51.51.5-1.61.6-0.91.6-1.71.5-0.50.61.41.9-0.31.8
Incentive Sensitization - Breakpoint0.92.03.21.6-1.61.61.31.5-1.51.51.5-1.51.6-0.91.5-1.71.5-0.40.61.31.8-0.21.7
Sum of active levers in priming session hrs 5-60.10.10.60.20.3-0.20.30.4-0.50.50.50.00.3-0.20.30.20.4-0.70.3-0.2-0.20.8-0.3
Progressive ratio0.00.11.00.5-0.30.30.50.1-0.20.20.2-0.00.2-1.0-0.1-0.5-0.00.4-0.0-0.3-0.10.2-0.1
Food seeking constrained by brief footshock2.32.84.71.9-1.81.81.92.2-2.12.12.1-1.81.9-1.02.0-0.41.9-1.61.71.30.80.80.5
Seeking ratio, punishment vs. effort0.61.42.90.9-1.21.20.81.5-1.41.41.4-1.51.10.21.70.31.4-1.71.41.40.90.10.8
Retroperitoneal fat weight1.67.031.4-2.10.9-0.9-3.3-0.80.9-0.9-0.9-0.8-1.74.81.25.60.1-4.63.02.31.1-4.61.4
Reaction time number correct0.30.94.1-0.10.2-0.30.5-0.20.2-0.2-0.20.8-0.5-1.2-0.9-0.5-0.51.0-1.2-1.4-1.62.0-1.7
Reaction time mean minus median0.31.83.01.5-1.61.61.31.5-1.61.61.6-1.71.4-0.71.7-0.11.4-1.71.51.30.80.00.6
Reaction time mean minus median AUC0.21.52.51.5-1.41.51.61.4-1.61.61.6-1.41.2-1.11.5-0.31.3-1.21.10.80.30.70.1
Reaction time num false alarms1.11.94.5-1.81.1-1.3-2.1-1.71.8-1.7-1.70.9-1.51.6-1.01.8-1.3-0.2-0.3-0.10.0-1.90.3
Reaction time num false alarms AUC0.51.12.6-1.41.0-1.2-1.6-1.31.4-1.4-1.40.9-1.01.0-1.00.8-1.00.4-0.7-0.20.2-1.20.4
Reaction time trials correct on left0.30.94.1-0.10.2-0.30.5-0.20.2-0.2-0.20.8-0.5-1.2-0.9-0.5-0.51.0-1.2-1.4-1.62.0-1.7
Reaction time trials on left0.30.94.1-0.10.2-0.30.6-0.10.2-0.2-0.20.7-0.5-1.3-0.9-0.5-0.51.0-1.1-1.4-1.62.0-1.7
Reaction time mean0.10.31.6-0.20.2-0.2-0.40.00.1-0.2-0.2-0.2-0.10.90.31.3-0.2-0.91.00.4-0.0-0.8-0.0
Reaction time mean AUC0.10.41.3-0.60.7-0.7-0.8-0.40.5-0.5-0.50.3-0.41.1-0.11.1-0.6-0.50.60.1-0.2-0.8-0.1
Median of all reaction times0.30.51.7-0.70.8-0.7-0.9-0.50.7-0.7-0.70.3-0.51.2-0.31.3-0.8-0.30.6-0.1-0.3-0.7-0.3
Reaction time omissions0.30.52.10.6-0.30.30.20.8-0.50.50.5-0.80.60.11.00.70.4-1.41.50.70.7-0.70.7
Reaction time false alarm rate1.01.44.8-1.31.0-1.1-1.9-1.21.3-1.3-1.30.6-0.91.6-0.61.4-1.0-0.20.10.20.7-2.20.9
Reaction time premature initiation rate2.23.58.71.5-2.12.10.91.9-1.61.61.6-2.41.40.32.50.81.8-3.02.52.41.8-1.31.7
Reaction time premature initiations0.72.04.31.4-1.81.91.21.8-1.41.41.4-1.91.2-0.61.80.31.4-2.11.61.50.9-0.10.7
Std. dev. reaction times0.51.53.61.0-1.11.20.61.2-1.21.21.2-1.51.10.31.60.51.2-1.91.81.61.2-0.91.1
Reaction time trials completed0.30.94.1-0.10.2-0.30.6-0.10.2-0.2-0.20.7-0.5-1.3-0.9-0.5-0.51.0-1.1-1.4-1.62.0-1.7
Reaction time trials AUC0.20.73.50.00.1-0.10.60.00.1-0.1-0.10.5-0.4-1.2-0.7-0.4-0.30.7-0.8-1.2-1.51.9-1.5
Run reversals in cocaine runway, females1.21.35.7-0.2-0.50.5-0.9-0.0-0.10.10.1-0.90.41.90.90.90.5-1.21.21.91.7-2.41.9
Run reversals in cocaine runway, males0.10.10.70.10.1-0.10.1-0.10.1-0.1-0.10.3-0.3-0.3-0.3-0.8-0.30.7-0.5-0.2-0.2-0.0-0.3
Latency to leave start box in cocaine runway1.42.03.5-1.91.8-1.8-1.8-1.61.6-1.6-1.61.5-1.51.4-1.41.2-1.50.4-1.0-0.9-0.9-0.5-0.8
Latency to leave start box in cocaine runway, F1.21.53.5-1.71.5-1.6-1.9-1.31.4-1.4-1.41.0-1.11.6-0.91.4-1.1-0.3-0.4-0.3-0.1-1.20.0
Latency to leave start box in cocaine runway, M0.60.61.0-0.60.8-0.8-0.4-0.70.7-0.7-0.70.9-0.80.1-0.90.0-0.90.7-0.9-0.9-1.00.6-1.0
Std. dev. time between licks in bursts0.91.73.21.0-1.31.20.81.4-1.51.51.5-1.51.40.01.6-0.11.8-1.71.01.71.5-0.11.4
Total sessions with >9 infusions1.11.42.71.6-1.61.51.61.3-1.31.31.3-1.11.2-1.60.9-1.51.00.10.30.40.40.80.3
Short access day 1 total inactive lever presses0.00.10.70.3-0.10.10.30.2-0.20.20.2-0.00.4-0.10.0-0.80.20.5-0.10.10.40.10.4
Short access day 10 total inactive lever presses0.31.83.2-1.61.2-1.3-1.4-1.61.6-1.6-1.61.3-1.81.0-1.51.2-1.50.5-1.3-1.2-1.20.1-1.1
Short access day 1 total infusions1.52.95.22.1-2.32.22.12.0-2.02.02.0-1.91.9-1.51.8-1.51.8-0.61.11.31.00.50.8
Short access day 10 total infusions0.50.92.21.2-1.31.21.10.9-0.90.90.9-1.01.0-1.10.8-1.50.90.30.40.60.80.10.7
Short access total infusions1.11.63.91.6-1.61.51.71.3-1.31.31.3-1.21.4-1.61.0-2.01.10.30.30.60.80.70.6
Short access day 1 locomotion1.11.95.61.9-1.71.72.11.3-1.31.31.3-1.01.3-2.40.8-2.10.90.50.1-0.00.21.5-0.0
Short access day 10 total locomotion0.31.42.31.5-1.41.41.51.3-1.31.31.3-1.21.5-1.21.1-1.31.2-0.40.50.71.00.60.8
Short access total locomotion0.40.62.10.9-1.00.91.20.5-0.50.50.5-0.40.7-1.30.2-1.40.30.5-0.4-0.30.01.2-0.1
One hour access (0.3 mA shock)0.91.01.91.3-1.41.31.11.1-1.11.11.1-1.11.1-1.11.0-1.21.0-0.20.60.80.90.10.8
Compulsive drug intake0.60.81.8-0.71.1-1.0-0.4-0.80.8-0.8-0.81.1-0.8-0.5-1.10.3-1.00.5-1.1-1.4-1.10.9-1.1
One hour access (shock baseline)0.61.63.51.6-1.61.51.61.4-1.41.41.4-1.21.4-1.31.1-1.91.20.20.50.81.00.40.9
Social response proportion0.40.51.7-1.01.0-1.0-0.9-0.50.6-0.6-0.60.6-0.91.0-0.41.3-0.5-0.8-0.0-0.3-0.6-0.0-0.5
Social responses0.50.72.4-0.90.5-0.6-1.2-0.60.6-0.5-0.50.1-0.71.50.01.5-0.3-1.30.50.50.2-1.20.3
Social time2.23.57.0-2.22.6-2.7-2.1-2.12.1-2.1-2.12.1-2.11.4-1.91.8-2.10.3-1.1-1.6-1.6-0.2-1.4
Soleus weight0.51.54.9-0.4-0.50.4-1.00.1-0.20.20.2-1.10.02.11.11.60.7-1.91.51.91.4-2.21.5
Bone: stiffness0.40.83.4-0.50.2-0.0-0.6-0.71.0-1.0-1.00.3-1.2-0.1-0.41.8-1.2-0.50.4-0.7-1.2-0.7-1.2
Tibialis anterior weight0.20.51.60.5-0.80.80.30.8-0.50.50.5-1.00.50.21.00.80.5-1.21.20.90.5-0.60.5
Time to tail flick, vehicle, before self-admin0.10.10.50.1-0.60.5-0.1-0.00.0-0.0-0.0-0.5-0.20.30.30.10.1-0.40.10.50.5-0.70.6
Time to tail flick, vehicle, after self-admin0.51.02.21.3-1.51.51.31.1-1.11.11.1-1.21.0-1.10.9-1.10.9-0.30.50.70.70.40.6
Time to tail flick, test, before self-admin0.70.82.60.6-0.90.90.10.6-0.70.70.7-1.10.40.51.00.50.9-1.01.61.30.9-1.40.9
Time to tail flick, test, after self-admin0.70.72.30.4-0.40.4-0.00.7-0.70.70.7-0.81.10.80.9-0.20.9-0.91.01.21.5-1.01.5
Delta time to tail flick, vehicle, before/after SA0.70.72.11.1-0.80.91.41.0-0.90.90.9-0.60.9-1.50.5-1.20.60.20.2-0.10.01.2-0.1
Delta time to tail flick, test, before/after SA0.40.51.0-0.81.0-1.0-0.5-0.60.6-0.6-0.60.9-0.30.4-0.80.0-0.60.5-0.9-0.8-0.50.7-0.5
Tibia length0.71.95.91.9-1.71.72.11.6-1.41.41.4-1.21.3-2.41.0-0.90.9-0.70.8-0.3-0.31.5-0.5
Ambulatory time before self-admin0.31.01.6-1.01.2-1.2-0.8-1.11.1-1.1-1.11.3-0.90.3-1.20.3-1.21.1-1.1-1.0-1.00.0-0.9
Ambulatory time after self-admin1.32.04.3-1.11.7-1.6-0.5-1.21.2-1.2-1.21.9-1.0-0.4-1.7-0.1-1.41.6-1.7-2.1-1.81.6-1.8
Bone: tissue strength2.02.16.7-0.90.6-0.5-0.4-1.41.5-1.5-1.51.1-1.7-0.8-1.41.4-1.90.5-0.9-2.1-2.61.0-2.6
Total heroin consumption0.00.00.1-0.20.3-0.3-0.2-0.10.0-0.0-0.00.2-0.30.1-0.10.3-0.1-0.20.2-0.2-0.40.0-0.4
Bone: trabecular number0.91.73.3-1.30.7-0.8-1.3-1.61.8-1.8-1.81.1-1.70.9-1.41.0-1.71.2-0.9-0.7-1.1-0.8-0.9
Bone: trabecular spacing0.81.12.31.2-0.60.71.51.3-1.41.41.4-0.61.3-1.30.8-1.11.2-0.50.50.00.31.50.1
Bone: trabecular thickness0.30.52.7-0.50.1-0.1-1.0-0.50.5-0.5-0.5-0.2-0.51.30.10.9-0.3-0.70.40.70.4-1.60.5
Bone: trabecular tissue density0.61.04.2-1.31.1-1.0-1.3-1.00.9-0.9-0.90.6-1.11.4-0.32.1-0.7-1.20.4-0.2-0.7-0.7-0.6
Water consumed over 24 hours0.40.81.3-1.11.0-1.0-1.0-1.01.0-1.0-1.01.0-1.01.0-1.00.1-0.81.0-1.1-0.4-0.4-0.1-0.3
Number of responses in last shaping day0.81.03.8-1.10.3-0.4-1.6-0.90.9-0.9-0.90.0-1.02.0-0.11.7-0.5-0.80.20.70.3-1.90.4