Hub : Genes

Lamtor1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	Lamtor1	0.1	0.08	1.5e-03	0.06	0.03	0.04	0.04	3.9e-04	6.1e-03	3.1e-03	2.1e-03
2	NAcc	gene expression	Lamtor1	0.02	0.02	8.1e-03	0	0.01	0.01	0	8.6e-02	6.5e-03	3.2e-02	5.2e-02
3	Adipose	gene expression	Lamtor1	0.14	0.08	2.3e-12	0.06	0.1	0.09	0.1	5.0e-07	6.3e-11	1.3e-10	1.2e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.1	0.2	0.3	-0.6	0.6	0.0
Area under the delay curve	0.3	0.4	0.9	-0.5	0.2	-0.9
BMI with tail	0.8	2.8	6.1	-0.6	1.4	2.5
BMI without tail	0.4	1.9	3.9	1.3	-0.5	2.0
Body weight	0.2	0.8	1.5	1.2	-1.0	0.2
Weight adjusted by age	0.1	0.4	0.8	0.7	-0.9	0.0
Bone surface	0.5	1.1	1.4	1.1	-1.2	-0.6
Bone volume	0.3	0.6	0.7	0.7	-0.8	-0.6
Breakpoint value in progressive ratio session	0.4	0.7	1.3	-0.9	1.1	0.4
Number of licking bursts	1.1	3.3	5.7	-2.4	1.9	-0.5
Context. condit. distance diff. score	2.3	2.8	4.8	2.2	-1.6	1.1
Locomotion velocity, session 1	1.6	1.8	2.2	-1.0	1.5	1.5
Locomotion distance, session 1	0.8	1.0	2.6	0.6	0.1	1.6
Locomotion velocity, session 2	0.6	0.7	1.9	0.2	0.5	1.4
Locomotion distance, session 2	0.7	1.0	2.7	0.4	0.4	1.7
Locomotion velocity, session 3	0.5	0.6	1.1	1.1	-0.7	0.3
Locomotion distance, session 3	0.5	0.6	1.0	1.0	-0.6	0.7
Stereotopy head waving bouts, day 3	0.3	0.4	1.0	0.1	-0.3	-1.0
Stereotopy head waving duration, day 3	0.2	0.2	0.4	0.7	-0.3	0.4
Locomotion velocity, session 7	0.6	0.6	1.2	-0.3	0.8	1.1
Locomotion distance, session 7	0.1	0.1	0.2	-0.5	0.4	-0.2
Stereotopy head waving bouts, day 7	2.6	3.0	5.6	2.4	-1.8	0.6
Stereotopy head waving duration, day 7	2.3	2.9	5.2	2.3	-1.6	0.8
Locomotion velocity, session 8	1.1	1.3	2.4	1.5	-1.3	0.3
Locomotion distance, session 8	1.9	2.8	4.3	2.1	-1.2	1.6
Degree of sensitization distance	0.5	0.5	1.4	-0.3	-0.2	-1.2
Degree of sensitization stereotypy	4.5	5.0	8.8	3.0	-2.3	0.8
Conditioned locomotion	0.4	0.5	1.2	-0.4	-0.1	-1.1
Cocaine response after cond. corrected	0.7	1.0	1.7	-1.3	1.1	-0.3
Cocaine response after cond. not corrected	0.6	0.8	1.3	-0.9	1.2	0.6
Cocaine response before conditioning	1.2	1.5	2.9	1.2	-0.3	1.7
Saline control response	2.5	3.5	5.2	2.0	-2.3	-1.1
Bone: connectivity density	0.6	1.0	1.6	-0.5	1.0	1.3
Bone: cortical apparent density	0.8	1.2	2.0	-1.4	1.0	-0.8
Bone: cortical area	0.2	0.3	0.4	0.6	-0.5	-0.3
Bone: cortical porosity	0.1	0.1	0.3	0.0	-0.3	-0.5
Bone: cortical porosity	0.1	0.2	0.2	0.2	-0.4	-0.5
Bone: cortical thickness	0.6	1.0	1.6	-0.8	1.3	0.8
Bone: cortical thickness	0.0	0.0	0.0	0.1	-0.2	-0.1
Bone: cortical tissue density	0.8	1.3	2.2	-1.5	1.0	-0.7
Condit. Reinf. active minus inactive responses	1.3	1.4	2.0	0.8	-1.4	-1.3
Condit. Reinf. active-inactive response ratio	2.6	2.7	3.6	1.2	-1.9	-1.8
Condit. Reinf. active responses	0.6	0.8	1.7	0.1	-0.7	-1.3
Condit. Reinf. inactive responses	0.4	0.5	0.8	-0.9	0.8	0.1
Incentive salience index mean	0.7	0.8	1.4	0.4	-1.0	-1.2
Condit. Reinf. lever presses	0.0	0.0	0.0	-0.0	0.0	0.0
Condit. Reinf. active minus inactive responses	5.7	8.7	13.4	3.7	-3.5	-0.4
Condit. Reinf. active-inactive response ratio	0.8	1.2	2.1	1.5	-1.2	0.3
Condit. Reinf. active responses	8.6	12.3	18.2	4.3	-4.3	-0.8
Condit. Reinf. inactive responses	4.2	6.3	9.5	2.9	-3.1	-1.1
Condit. Reinf. lever presses	11.1	16.1	27.9	5.3	-4.5	0.5
Condit. Reinf. lever reinforcers received	9.2	12.9	19.3	4.4	-4.3	-0.7
Conditioned reinforcement - actives	0.0	0.2	0.3	0.6	-0.1	0.3
Conditioned reinforcement - inactives	0.3	0.7	1.3	-0.8	0.4	-1.1
Conditioned locomotion	0.5	0.8	1.9	0.6	0.0	1.4
Patch foraging indifference point 0 sec	0.8	2.2	3.9	2.0	-1.5	0.6
Patch foraging indifference point AUC	0.2	0.4	0.7	0.6	-0.8	-0.4
Delay disc. indifference point, 0s delay	0.7	0.7	1.2	1.1	-1.0	-0.0
Delay disc. indifference point, 16s delay	0.6	0.8	2.4	-0.3	-0.1	-1.5
Delay disc. indifference point, 2s delay	0.8	0.9	1.1	0.9	-1.1	-0.9
Delay disc. indifference point, 24s delay	0.7	1.1	1.5	-1.1	0.8	-1.2
Delay disc. indifference point, 4s delay	1.4	1.4	2.0	1.2	-1.4	-0.9
Delay disc. indifference point, 8s delay	0.2	0.3	0.4	-0.7	0.4	-0.5
Indifference point function ln k	0.1	0.2	0.4	0.6	-0.0	0.6
Indifference point function log k	0.1	0.2	0.4	0.6	-0.0	0.6
Patch foraging total patch changes 0 sec	0.6	1.8	3.3	1.8	-1.3	0.7
Patch foraging total patch changes 12 sec	0.9	1.2	1.8	1.3	-1.3	-0.5
Patch foraging total patch changes 18 sec	0.5	1.3	2.2	1.5	-1.3	0.0
Patch foraging total patch changes 24 sec	0.4	1.3	2.0	1.4	-1.4	-0.4
Patch foraging total patch changes 6 sec	0.3	0.6	0.8	0.9	-0.8	0.5
Patch foraging time to switch 0 sec	1.0	3.8	6.8	-2.6	2.1	-0.6
Patch foraging water rate 0 sec	0.8	2.8	4.9	2.2	-1.8	0.5
Patch foraging water rate 12 sec	0.7	2.7	5.5	1.6	-0.3	2.4
Patch foraging water rate 18 sec	1.2	2.6	4.4	2.1	-1.4	1.2
Patch foraging water rate 24 sec	0.6	0.9	2.2	0.6	0.3	1.5
Patch foraging water rate 6 sec	0.8	1.2	2.4	1.1	-0.0	1.5
Seeking ratio, delayed vs. immediate footshock	1.5	2.1	3.3	-1.7	1.8	0.5
Distance traveled before self-admin	0.3	0.8	0.9	-0.8	1.0	0.9
Distance traveled after self-admin	0.8	1.5	3.1	-0.3	1.1	1.8
Extensor digitorum longus weight	0.0	0.2	0.3	-0.5	0.5	0.0
Bone: elastic displacement	2.0	2.5	3.9	-1.7	2.0	1.0
Bone: elastic work	3.7	4.9	7.0	-2.2	2.7	1.7
Bone: endosteal estimation	1.5	3.6	5.1	1.9	-2.3	-1.4
Bone: endosteal perimeter	1.6	3.8	5.6	2.2	-2.4	-1.0
Epididymis fat weight	0.2	0.9	1.5	-1.2	1.1	0.2
Delta time in closed arm before/after self-admin	0.8	0.7	1.1	-1.0	0.6	-0.8
Delta time in open arm before/after self-admin	2.6	3.0	4.5	2.1	-2.1	-0.6
Diff in mean of infusions in LGA sessions	1.3	2.3	4.3	-1.5	0.7	-2.1
Delay discount exponential model param	0.2	0.3	0.6	0.6	-0.4	0.7
Extinction: sum of active levers before priming	0.1	0.2	0.2	0.4	-0.4	-0.3
Active lever presses in extinction session 6	0.8	0.8	2.2	0.5	0.1	1.5
Bone: final force	0.6	0.9	2.4	-0.6	-0.1	-1.6
Bone: final moment	0.4	0.7	1.9	-0.4	-0.2	-1.4
Food consumed during 24 hour testing period	1.0	2.1	3.5	1.9	-1.3	1.0
Glucose	0.2	0.3	0.8	-0.0	0.4	0.9
Heart weight	0.7	1.2	1.8	1.3	-1.3	-0.3
Delay discount hyperbolic model param	0.2	0.3	0.7	0.4	-0.2	0.8
Intermittent access intake day 1-15 change	0.4	2.0	5.3	0.4	0.7	2.3
Intermittent access intake escalation	0.3	1.7	4.7	0.6	0.4	2.2
Intermittent access intake escalation 2	0.2	0.4	1.1	0.2	0.3	1.0
Intermitt. access day 1 inactive lever presses	0.1	1.7	2.4	-1.5	1.2	-1.2
Intermitt. access day 15 inactive lever presses	0.0	0.2	0.4	-0.6	0.6	-0.1
Intermitt. access escalation Index	0.0	0.1	0.1	0.1	-0.2	-0.3
Intermittent access day 1 total infusions	0.4	1.3	2.1	1.4	-1.3	-0.4
Intermittent access day 15 total infusions	0.3	0.7	1.2	1.1	-0.7	0.6
Intermittent access terminal intake (last 3 days)	0.6	1.0	2.1	1.4	-1.0	0.3
Intermittent access total infusions	1.0	1.1	2.3	1.5	-1.0	0.3
Intermittent access day 1 locomotion	0.2	0.3	0.5	0.3	-0.5	-0.7
Intermittent access day 15 total locomotion	0.1	0.5	1.2	0.2	0.4	1.1
Intermittent access total locomotion	0.3	0.3	0.7	0.8	-0.6	0.2
Intermittent access standard deviation	0.1	0.4	1.0	0.1	0.5	1.0
Left kidney weight	0.1	0.4	0.7	0.8	-0.6	0.4
Right kidney weight	0.1	0.9	1.5	1.1	-1.2	-0.3
Cocaine induced anxiety	1.0	2.8	4.8	-2.2	1.4	-1.2
Post-drug Anxiety	1.5	1.7	3.4	-1.2	0.3	-1.9
Baseline Anxiety	1.5	2.5	4.0	1.7	-2.0	-0.8
Tail length	2.0	10.6	15.7	3.2	-4.0	-2.5
Length with tail	2.1	9.1	12.7	3.0	-3.6	-2.4
Length without tail	0.1	0.4	0.5	0.5	-0.5	-0.7
Times rat made contact with spout	0.1	0.2	0.4	-0.2	0.1	-0.7
Lifetime Intake	1.3	1.6	3.2	1.8	-1.2	0.4
Liver weight, left	0.3	0.5	1.4	-0.3	-0.1	-1.2
Liver weight, right	0.5	0.9	2.4	-0.3	-0.4	-1.6
Locomotor activity	0.3	0.4	0.6	0.8	-0.5	0.7
Locomotor testing distance	0.7	1.7	3.0	1.7	-1.4	0.5
Locomotor testing rearing	0.3	1.2	1.8	1.3	-1.3	-0.4
Locomotion in novel chamber	1.2	1.6	2.2	-1.1	1.5	1.2
Locomotion in novel chamber post-restriction	0.2	0.7	1.2	1.1	-0.5	0.8
Fecal boli incidents, locomotor time 1	0.5	1.3	2.2	-1.5	1.2	-0.5
Change in fecal boli incidents, locomotor task	0.2	0.2	0.4	0.5	-0.6	0.0
Time >=10cm from walls, locomotor time 1	0.4	0.5	1.0	0.7	-1.0	-0.3
Bouts of movement, locomotor time 1	0.4	0.6	1.2	0.2	-0.6	-1.1
Total resting periods, locomotor time 1	0.1	0.2	0.4	-0.3	-0.0	-0.6
Rest time, locomotor task time 1	0.1	0.1	0.3	0.1	-0.2	-0.6
Distance moved, locomotor task time 1	0.0	0.1	0.1	0.1	0.2	0.4
Vertical activity count, locomotor time 1	0.0	0.0	0.1	0.2	-0.1	-0.3
Time >=10cm from walls, locomotor time 2	1.4	3.9	6.1	1.9	-2.5	-1.3
Bouts of movement, locomotor time 2	0.7	2.4	4.8	0.6	-1.4	-2.2
Total resting periods, locomotor time 2	0.4	1.6	3.9	0.2	-0.9	-2.0
Rest time, locomotor task time 2	1.0	1.7	2.6	-1.6	1.6	-0.0
Distance moved, locomotor task time 2	1.6	2.1	3.4	1.8	-1.7	0.0
Vertical activity count, locomotor time 2	0.4	0.9	1.2	0.7	-1.1	-1.0
Light reinforcement 1	0.9	3.9	5.3	-2.3	2.3	1.1
Light reinforcement 2	1.6	3.5	7.1	-0.9	1.6	2.7
Bone: marrow area	1.3	3.1	4.3	1.7	-2.1	-1.4
Bone: maximum diameter	1.7	3.3	4.8	2.2	-2.2	-0.7
Bone: maximum force	0.2	0.3	0.9	-0.3	-0.0	-0.9
Bone: maximum moment	0.1	0.2	0.5	-0.1	-0.1	-0.7
Mean time between licks in bursts	1.4	8.1	12.2	2.9	-3.5	-2.0
Mean num. licks in bursts	1.1	2.9	5.1	2.3	-1.9	0.3
Cd content in liver	0.4	0.4	1.2	-0.3	-0.3	-1.1
Co content in liver	2.5	3.0	4.0	1.8	-2.0	-1.3
Cu content in liver	1.3	1.6	2.0	1.0	-1.4	-1.3
Fe content in liver	0.0	0.0	0.1	0.1	0.0	-0.2
K content in liver	0.2	0.2	0.3	-0.6	0.4	-0.3
Mg content in liver	0.2	0.2	0.5	-0.0	0.2	0.7
Mn content in liver	1.9	2.1	3.4	-1.3	1.8	1.1
Na content in liver	0.6	0.7	1.1	1.1	-0.5	0.8
Rb content in liver	0.3	0.4	0.5	0.5	-0.6	-0.7
Se content in liver	3.9	4.6	7.1	-2.7	2.6	-0.0
Sr content in liver	1.3	1.1	3.0	0.3	0.4	1.7
Zn content in liver	1.4	1.6	2.7	1.6	-1.3	0.6
Bone: minimum diameter	1.2	2.2	2.8	1.3	-1.7	-1.5
Time in familiar zone, hab. session 1	0.1	0.1	0.2	0.5	-0.4	0.1
Time in novel zone, hab. session 1	0.2	0.3	0.6	-0.4	0.1	-0.8
Total zone transitions, hab. session 1	0.2	0.3	0.8	0.4	0.1	0.9
Total locomotion distance, hab. session 1	0.4	0.6	1.5	-0.1	-0.5	-1.2
Locomotion velocity, hab. session 1	0.2	0.3	0.9	-0.1	-0.3	-0.9
Time in familiar zone, hab. session 2	2.7	3.0	4.7	1.9	-2.2	-0.8
Time in novel zone, hab. session 2	2.4	2.6	3.8	-1.3	1.9	1.5
Total zone transitions, hab. session 2	1.6	2.0	3.2	1.8	-1.1	1.3
Total locomotion distance, hab. session 2	0.9	1.1	1.7	1.0	-1.3	-0.8
Locomotion velocity, hab. session 2	0.8	1.1	1.6	1.0	-1.3	-0.9
Novel to familiar place preference ratio	1.2	1.6	3.4	0.4	-1.1	-1.9
Novelty place preference	1.2	1.5	3.0	0.5	-1.1	-1.7
Time in novel zone, NPP test	1.4	1.8	3.1	0.7	-1.3	-1.8
Total zone transitions, NPP test	0.9	1.4	3.4	-0.2	0.8	1.8
Total locomotion distance, NPP test	0.2	0.3	0.4	-0.6	0.6	0.5
Locomotion velocity, NPP test	0.5	0.7	0.9	-0.8	1.0	0.6
Intraocular pressure	0.3	0.5	0.7	-0.5	0.6	0.8
Delta distance traveled before/after self-admin	1.0	1.2	2.2	1.5	-1.1	0.0
Delta ambulatory time before/after self-admin	0.5	0.9	1.7	1.3	-0.9	0.2
Parametrial fat weight	1.3	3.0	4.3	-1.1	1.9	2.1
Pavlov. Cond. lever latency	0.7	0.9	1.4	-1.0	1.2	0.6
Pavlov. Cond. magazine entry latency	2.4	3.1	5.3	2.3	-2.0	0.3
Pavlov. Cond. change in total contacts	1.7	1.8	2.7	1.3	-1.7	-1.0
Pavlov. Cond. index score	1.8	2.3	3.6	1.9	-1.8	-0.2
Pavlov. Cond. latency score	1.7	2.1	3.2	1.8	-1.7	-0.3
Pavlov. Cond. lever contacts	0.8	0.9	1.4	1.2	-1.1	-0.3
Pavlov. Cond. magazine entry number	2.3	2.9	4.7	-2.2	2.0	0.1
Pavlov. Cond. intertrial magazine entries	0.6	0.8	1.4	-1.2	0.8	-0.5
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.9	3.0	1.7	-1.6	-0.2
Pavlov. Cond. response bias	1.0	1.3	2.2	1.5	-1.3	0.2
Pavlov. Cond. lever latency	12.4	17.5	31.0	-5.6	4.4	-1.4
Pavlov. Cond. magazine entry latency	2.9	4.1	6.4	2.2	-0.9	2.5
Pavlov. Cond. change in total contacts	6.3	15.2	26.9	5.2	-4.1	1.5
Pavlov. Cond. index score	7.7	12.1	21.3	4.6	-3.4	1.8
Pavlov. Cond. latency score	6.5	10.4	18.2	4.3	-3.0	2.0
Pavlov. Cond. lever contacts	11.0	16.3	28.5	5.3	-4.3	1.2
Pavlov. Cond. magazine entry number	4.8	6.2	9.8	-3.1	1.9	-2.3
Pavlov. Cond. intertrial magazine entries	0.8	1.9	3.4	0.6	-1.4	-1.9
Pavlov. Cond. lever-magazine prob. diff.	7.6	11.7	20.7	4.5	-3.4	1.7
Pavlov. Cond. response bias	11.8	16.4	29.0	5.4	-4.1	1.8
Time in closed arm before self-admin	1.0	1.8	3.0	1.7	-1.2	1.0
Time in closed arm after self-admin	0.3	0.4	0.6	-0.8	0.7	-0.2
Time in open arm before self-admin	4.2	5.1	7.8	-2.8	2.7	0.4
Time in open arm after self-admin	0.2	0.2	0.2	0.4	-0.4	-0.4
Bone: periosteal estimation	0.8	1.8	2.3	1.5	-1.5	-0.8
Bone: periosteal perimeter	0.8	1.7	2.7	1.6	-1.5	-0.3
Bone: post-yield work	0.1	0.2	0.4	0.6	-0.5	-0.1
Progressive ratio test 1 active lever presses	0.0	0.0	0.0	0.1	-0.0	0.0
Progressive ratio test 1 breakpoint	0.0	0.0	0.0	0.1	-0.1	-0.0
Progressive ratio test 1 inactive lever presses	0.1	0.2	0.3	-0.4	0.5	-0.3
Progressive ratio test 2 active lever presses	0.1	0.2	0.3	0.6	-0.5	-0.2
Progressive ratio test 2 breakpoint	0.2	0.2	0.4	0.6	-0.5	-0.1
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.2	0.2	0.1	0.4
Incentive Sensitization - Responses	0.1	0.4	0.6	0.8	-0.7	-0.2
Incentive Sensitization - Breakpoint	0.1	0.2	0.5	0.7	-0.5	0.1
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.3	0.3	-0.1	0.5
Progressive ratio	0.3	1.0	2.6	0.5	0.3	1.6
Food seeking constrained by brief footshock	1.6	2.0	3.1	1.8	-1.7	-0.1
Seeking ratio, punishment vs. effort	0.7	1.5	2.2	1.0	-1.5	-1.2
Retroperitoneal fat weight	0.4	2.0	3.4	-1.8	1.6	-0.3
Reaction time number correct	0.1	0.2	0.4	0.2	0.4	0.7
Reaction time mean minus median	0.1	0.6	0.9	0.8	-1.0	-0.5
Reaction time mean minus median AUC	0.1	0.5	0.8	0.9	-0.8	-0.3
Reaction time num false alarms	1.3	2.1	3.4	-1.9	1.1	-1.4
Reaction time num false alarms AUC	0.9	2.0	3.4	-1.8	1.2	-1.1
Reaction time trials correct on left	0.1	0.2	0.4	0.2	0.4	0.7
Reaction time trials on left	0.1	0.2	0.5	0.2	0.4	0.7
Reaction time mean	0.7	1.6	3.0	-1.2	0.5	-1.7
Reaction time mean AUC	0.7	1.7	2.9	-1.3	0.6	-1.7
Median of all reaction times	1.4	2.2	2.9	-1.7	0.9	-1.7
Reaction time omissions	0.1	0.2	0.3	-0.5	0.5	-0.2
Reaction time false alarm rate	1.4	2.0	3.6	-1.9	1.1	-1.1
Reaction time premature initiation rate	1.5	2.3	3.6	1.7	-1.9	-0.6
Reaction time premature initiations	0.4	1.3	2.2	1.5	-1.3	-0.1
Std. dev. reaction times	0.4	1.3	3.1	0.2	-0.9	-1.8
Reaction time trials completed	0.1	0.2	0.5	0.2	0.4	0.7
Reaction time trials AUC	0.0	0.1	0.3	0.2	0.3	0.5
Run reversals in cocaine runway, females	0.3	0.4	0.6	0.6	-0.8	-0.3
Run reversals in cocaine runway, males	0.3	0.3	0.4	-0.6	0.6	-0.2
Latency to leave start box in cocaine runway	0.7	1.0	1.4	-1.2	0.8	-0.9
Latency to leave start box in cocaine runway, F	1.0	1.2	2.8	-0.9	0.2	-1.7
Latency to leave start box in cocaine runway, M	1.0	1.0	1.3	-1.0	1.2	0.8
Std. dev. time between licks in bursts	1.5	2.8	3.7	1.4	-1.9	-1.7
Total sessions with >9 infusions	1.7	2.2	4.2	2.0	-1.5	0.3
Short access day 1 total inactive lever presses	0.2	0.4	1.1	0.1	-0.3	-1.0
Short access day 10 total inactive lever presses	0.2	1.4	2.3	-1.5	1.1	-0.8
Short access day 1 total infusions	1.7	3.4	5.1	2.3	-2.2	-0.6
Short access day 10 total infusions	1.0	1.7	3.3	1.8	-1.3	0.3
Short access total infusions	1.7	2.4	4.4	2.1	-1.6	0.1
Short access day 1 locomotion	0.3	0.5	0.7	0.8	-0.5	0.7
Short access day 10 total locomotion	0.1	0.6	1.1	1.0	-0.4	0.7
Short access total locomotion	0.1	0.2	0.5	0.4	0.1	0.7
One hour access (0.3 mA shock)	0.4	0.5	0.9	0.9	-0.3	0.8
Compulsive drug intake	1.4	2.0	2.8	-1.5	1.7	0.9
One hour access (shock baseline)	0.7	1.7	3.4	1.9	-1.0	0.8
Social response proportion	0.2	0.3	0.5	-0.7	0.6	-0.1
Social responses	0.3	0.4	1.1	-0.3	-0.0	-1.0
Social time	1.2	1.9	2.8	-1.7	1.7	0.1
Soleus weight	0.2	0.7	1.7	-0.6	-0.1	-1.3
Bone: stiffness	1.0	1.8	4.7	-0.8	-0.2	-2.2
Tibialis anterior weight	0.1	0.4	0.7	0.4	-0.6	-0.9
Time to tail flick, vehicle, before self-admin	0.6	0.7	1.1	1.0	-0.3	1.0
Time to tail flick, vehicle, after self-admin	0.5	1.1	1.5	1.2	-1.2	-0.6
Time to tail flick, test, before self-admin	2.6	3.0	4.5	2.0	-2.1	-0.9
Time to tail flick, test, after self-admin	2.4	2.5	3.5	1.2	-1.9	-1.6
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.7	-0.0	-0.3	-0.9
Delta time to tail flick, test, before/after SA	0.7	0.9	1.5	-1.2	1.1	0.1
Tibia length	0.3	0.9	1.5	1.2	-1.2	-0.1
Ambulatory time before self-admin	0.3	0.8	1.1	-1.0	1.0	0.7
Ambulatory time after self-admin	0.5	0.7	1.9	0.4	0.4	1.4
Bone: tissue strength	2.1	2.2	3.2	-0.9	1.6	1.8
Total heroin consumption	0.2	0.2	0.5	0.4	-0.1	0.7
Bone: trabecular number	0.8	1.5	2.5	-1.3	1.6	0.7
Bone: trabecular spacing	0.5	0.7	1.8	0.6	-0.1	1.4
Bone: trabecular thickness	0.9	1.3	3.4	-0.2	-0.6	-1.8
Bone: trabecular tissue density	1.8	3.1	8.3	-1.0	-0.3	-2.9
Water consumed over 24 hours	0.1	0.2	0.4	-0.6	0.6	-0.0
Number of responses in last shaping day	1.1	1.5	3.4	-1.0	-0.1	-1.8