Stard10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Stard10 0.13 0.07 1.2e-11 0.09 0.09 0.09 0.09 4.6e-10 2.7e-10 4.9e-10 6.1e-10
2 Liver intron excision ratio chr1_155722596_155722952 0.04 0.03 1.9e-03 0 0.01 0 0 1.5e-01 1.7e-02 1.6e-01 1.2e-01
3 PL alternative polyA NM_001013069.1 0.05 0.03 4.1e-04 0.02 0.03 0.03 0.03 1.9e-03 2.9e-04 3.3e-04 3.7e-04
4 Eye mRNA stability Stard10 0.71 0.17 8.8e-03 -0.01 -0.02 -0.02 -0.01 4.6e-01 9.3e-01 6.8e-01 4.6e-01
5 PL alternative polyA XM_039106105.1 0.05 0.03 1.8e-04 0.02 0.03 0.04 0.03 1.1e-03 1.1e-04 8.2e-05 1.3e-04
6 Brain alternative polyA NM_001013069.1 0.07 0.04 1.7e-04 0.06 0.04 0.04 0.05 2.2e-06 2.4e-04 5.7e-05 2.0e-05
7 Brain alternative polyA XM_039106105.1 0.07 0.04 1.2e-04 0.05 0.04 0.04 0.04 2.2e-05 1.6e-04 6.4e-05 4.7e-05
8 Brain gene expression Stard10 0.05 0.04 9.2e-03 0.02 0.01 0.02 0.02 3.3e-03 1.5e-02 7.6e-03 7.3e-03
9 Liver isoform ratio XM_039106105.1 0.05 0.04 7.8e-04 0.03 0.02 0.01 0.02 6.7e-04 5.5e-03 4.0e-02 2.5e-03
10 Liver isoform ratio NM_001013069.1 0.06 0.05 1.8e-03 0.01 0.01 0.01 0.01 3.7e-02 9.3e-03 7.1e-02 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.40.61.1-0.1-0.7-0.60.1-0.61.0-1.01.0-1.0-0.6
Area under the delay curve0.10.10.70.8-0.3-0.10.1-0.1-0.10.1-0.10.10.5
BMI with tail0.51.56.10.1-1.0-1.62.5-1.40.3-0.30.3-0.7-1.5
BMI without tail0.40.91.7-0.11.30.90.50.8-1.21.2-1.21.10.5
Body weight1.14.57.60.81.81.8-0.62.1-2.82.8-2.82.51.9
Weight adjusted by age0.60.71.4-0.31.21.0-0.60.9-0.70.7-0.71.00.7
Bone surface0.50.83.1-0.91.01.1-1.81.1-0.30.3-0.30.50.3
Bone volume0.40.62.3-0.50.80.9-1.51.0-0.50.5-0.50.50.5
Breakpoint value in progressive ratio session0.40.40.8-0.3-0.6-0.70.9-0.90.5-0.50.5-0.5-0.8
Number of licking bursts1.61.86.12.5-1.8-1.52.0-1.30.4-0.40.4-0.70.3
Context. condit. distance diff. score1.01.25.4-2.31.51.2-1.40.9-0.20.2-0.20.5-0.5
Locomotion velocity, session 11.92.12.6-0.4-1.3-1.51.4-1.51.5-1.51.5-1.6-1.6
Locomotion distance, session 10.50.62.4-1.60.1-0.20.6-0.30.6-0.60.6-0.7-1.4
Locomotion velocity, session 20.20.31.0-0.7-0.0-0.31.0-0.30.1-0.10.1-0.5-0.9
Locomotion distance, session 20.20.31.0-1.00.2-0.20.7-0.1-0.20.2-0.2-0.3-0.9
Locomotion velocity, session 30.30.31.5-1.20.50.5-1.00.40.2-0.20.20.0-0.3
Locomotion distance, session 30.70.72.9-1.70.30.2-0.8-0.00.9-0.90.9-0.6-1.0
Stereotopy head waving bouts, day 30.60.81.30.90.40.6-0.30.7-1.11.1-1.10.81.1
Stereotopy head waving duration, day 30.00.00.3-0.50.10.00.10.0-0.00.0-0.0-0.2-0.3
Locomotion velocity, session 70.40.50.6-0.1-0.6-0.80.7-0.80.7-0.70.7-0.6-0.8
Locomotion distance, session 70.10.10.50.7-0.2-0.1-0.3-0.1-0.20.2-0.20.20.4
Stereotopy head waving bouts, day 71.01.15.6-2.41.31.1-1.21.00.1-0.10.1-0.0-0.7
Stereotopy head waving duration, day 71.01.36.4-2.51.41.1-1.11.00.0-0.00.0-0.0-0.8
Locomotion velocity, session 80.70.81.9-1.41.21.1-1.31.1-0.50.5-0.50.70.0
Locomotion distance, session 80.91.35.4-2.31.51.1-0.81.0-0.70.7-0.70.5-0.7
Degree of sensitization distance2.62.64.41.80.70.9-0.41.1-2.12.1-2.11.82.0
Degree of sensitization stereotypy2.12.310.4-3.22.01.6-1.81.4-0.00.0-0.00.3-0.8
Conditioned locomotion0.60.71.30.90.00.4-1.00.6-0.90.9-0.90.61.2
Cocaine response after cond. corrected0.60.62.51.6-0.9-0.81.4-0.70.1-0.10.1-0.00.3
Cocaine response after cond. not corrected0.70.81.90.6-1.0-1.11.4-1.00.8-0.80.8-0.6-0.7
Cocaine response before conditioning1.31.65.2-2.30.2-0.3-0.2-0.61.4-1.41.4-1.1-1.9
Saline control response3.34.37.2-0.92.32.5-2.72.5-2.02.0-2.01.91.6
Bone: connectivity density1.72.74.2-1.0-1.1-1.31.1-1.52.1-2.12.1-1.9-1.9
Bone: cortical apparent density0.70.94.42.1-0.5-0.20.60.1-0.80.8-0.80.81.3
Bone: cortical area1.21.82.5-0.01.21.3-1.41.5-1.61.6-1.61.31.1
Bone: cortical porosity0.30.31.3-0.80.20.2-1.10.10.5-0.50.5-0.4-0.2
Bone: cortical porosity0.20.31.5-0.70.20.3-1.20.20.4-0.40.4-0.2-0.1
Bone: cortical thickness0.10.10.40.3-0.5-0.50.6-0.3-0.10.1-0.1-0.2-0.3
Bone: cortical thickness0.10.10.2-0.10.20.2-0.40.3-0.40.4-0.40.20.2
Bone: cortical tissue density0.70.94.32.1-0.6-0.30.60.0-0.70.7-0.70.81.2
Condit. Reinf. active minus inactive responses1.41.62.10.21.21.4-1.31.4-1.31.3-1.31.51.4
Condit. Reinf. active-inactive response ratio2.12.23.70.11.51.7-1.91.7-1.31.3-1.31.61.7
Condit. Reinf. active responses0.91.01.70.60.70.9-1.01.1-1.21.2-1.21.01.3
Condit. Reinf. inactive responses0.10.10.30.5-0.5-0.40.4-0.2-0.20.2-0.2-0.30.0
Incentive salience index mean0.91.11.40.30.91.1-1.01.2-1.11.1-1.11.01.1
Condit. Reinf. lever presses0.00.00.1-0.00.00.10.20.2-0.10.1-0.1-0.2-0.1
Condit. Reinf. active minus inactive responses6.07.412.9-2.43.63.4-3.13.2-2.42.4-2.42.41.2
Condit. Reinf. active-inactive response ratio0.80.82.1-1.41.31.1-1.01.0-0.40.4-0.40.6-0.1
Condit. Reinf. active responses8.812.219.6-2.54.44.2-3.74.1-3.43.4-3.43.11.9
Condit. Reinf. inactive responses6.58.010.8-1.33.33.3-2.93.2-3.13.1-3.12.51.9
Condit. Reinf. lever presses9.312.623.6-4.34.94.3-4.04.1-2.92.9-2.92.80.6
Condit. Reinf. lever reinforcers received8.612.220.2-2.94.54.3-3.84.2-3.23.2-3.23.01.6
Conditioned reinforcement - actives0.30.31.5-1.20.30.2-0.80.20.4-0.40.4-0.4-0.7
Conditioned reinforcement - inactives0.30.31.11.1-0.10.2-0.50.3-0.50.5-0.50.40.9
Conditioned locomotion0.70.94.5-2.10.40.1-0.5-0.10.7-0.70.7-0.7-1.4
Patch foraging indifference point 0 sec1.01.53.9-2.01.71.4-1.61.2-0.80.8-0.80.9-0.2
Patch foraging indifference point AUC0.70.91.40.30.91.0-0.41.0-1.21.2-1.20.61.0
Delay disc. indifference point, 0s delay0.60.60.9-0.50.90.9-0.51.0-1.01.0-1.00.50.3
Delay disc. indifference point, 16s delay0.20.30.90.9-0.20.1-0.50.1-0.30.3-0.30.30.9
Delay disc. indifference point, 2s delay1.01.11.7-0.21.11.2-0.91.3-1.01.0-1.01.30.9
Delay disc. indifference point, 24s delay0.40.42.41.5-0.8-0.50.4-0.4-0.20.2-0.20.00.8
Delay disc. indifference point, 4s delay1.71.82.40.01.41.5-1.01.5-1.51.5-1.51.41.2
Delay disc. indifference point, 8s delay0.10.10.20.5-0.4-0.30.1-0.30.2-0.20.2-0.30.1
Indifference point function ln k0.40.61.7-1.3-0.2-0.3-0.6-0.30.9-0.90.9-0.3-1.1
Indifference point function log k0.40.61.7-1.3-0.2-0.3-0.6-0.30.9-0.90.9-0.3-1.1
Patch foraging total patch changes 0 sec0.71.13.1-1.81.51.1-1.21.0-0.70.7-0.70.8-0.3
Patch foraging total patch changes 12 sec1.92.53.5-0.21.71.7-1.11.7-1.91.9-1.91.71.3
Patch foraging total patch changes 18 sec0.60.81.6-0.91.31.1-1.11.0-0.80.8-0.80.40.3
Patch foraging total patch changes 24 sec1.72.12.7-0.31.71.6-1.11.6-1.61.6-1.61.61.1
Patch foraging total patch changes 6 sec0.10.20.6-0.80.70.5-0.40.3-0.40.4-0.40.1-0.1
Patch foraging time to switch 0 sec1.72.65.12.1-2.3-1.91.7-1.91.3-1.31.3-1.2-0.1
Patch foraging water rate 0 sec1.01.73.8-2.01.81.5-1.61.5-0.90.9-0.90.8-0.1
Patch foraging water rate 12 sec0.50.84.8-2.20.80.20.30.10.0-0.00.0-0.0-1.5
Patch foraging water rate 18 sec1.11.53.4-1.81.71.3-0.51.2-1.01.0-1.01.4-0.2
Patch foraging water rate 24 sec0.40.51.8-1.3-0.1-0.40.3-0.40.6-0.60.6-0.4-1.3
Patch foraging water rate 6 sec0.30.42.4-1.60.50.1-0.10.20.1-0.10.10.2-1.1
Seeking ratio, delayed vs. immediate footshock2.22.53.50.6-1.8-1.81.3-1.71.9-1.91.9-1.4-1.2
Distance traveled before self-admin0.80.92.31.1-1.0-1.01.5-1.20.7-0.70.7-0.7-0.2
Distance traveled after self-admin0.30.40.6-0.7-0.4-0.40.4-0.60.6-0.60.6-0.6-0.8
Extensor digitorum longus weight0.10.20.80.9-0.0-0.20.8-0.1-0.50.5-0.50.30.3
Bone: elastic displacement2.83.25.20.6-2.0-2.02.3-2.01.7-1.71.7-1.8-1.4
Bone: elastic work5.26.68.70.3-2.6-2.82.9-2.92.7-2.72.7-2.8-2.3
Bone: endosteal estimation1.83.96.8-0.42.22.3-2.62.3-1.81.8-1.82.01.7
Bone: endosteal perimeter2.04.16.6-0.92.42.4-2.62.4-1.91.9-1.91.81.4
Epididymis fat weight0.20.62.61.6-0.1-0.11.1-0.0-0.50.5-0.50.70.9
Delta time in closed arm before/after self-admin1.41.44.82.20.10.30.30.4-1.21.2-1.21.21.8
Delta time in open arm before/after self-admin1.81.74.7-1.51.71.6-2.21.6-0.80.8-0.80.80.4
Diff in mean of infusions in LGA sessions0.50.53.21.8-0.7-0.10.2-0.0-0.10.1-0.1-0.01.2
Delay discount exponential model param0.10.10.7-0.90.40.3-0.30.20.0-0.00.00.0-0.4
Extinction: sum of active levers before priming0.10.00.10.2-0.3-0.30.4-0.30.0-0.00.00.1-0.1
Active lever presses in extinction session 61.11.04.5-2.10.2-0.1-0.4-0.30.9-0.90.9-0.9-1.5
Bone: final force0.91.53.21.20.40.8-1.81.1-1.21.2-1.21.11.7
Bone: final moment0.91.53.20.90.61.0-1.81.2-1.31.3-1.31.21.6
Food consumed during 24 hour testing period1.01.26.5-2.61.20.9-1.20.80.2-0.20.2-0.1-1.0
Glucose0.50.81.5-0.8-0.4-0.60.9-0.51.2-1.21.2-0.2-1.2
Heart weight0.40.51.7-1.30.90.8-1.00.8-0.40.4-0.4-0.2-0.1
Delay discount hyperbolic model param0.10.10.5-0.70.2-0.0-0.1-0.00.2-0.20.2-0.2-0.5
Intermittent access intake day 1-15 change0.60.62.0-1.40.1-0.30.9-0.20.3-0.30.3-0.6-1.4
Intermittent access intake escalation0.60.62.3-1.40.0-0.41.0-0.30.4-0.40.4-0.7-1.5
Intermittent access intake escalation 20.10.10.6-0.0-0.1-0.30.8-0.2-0.10.1-0.1-0.1-0.5
Intermitt. access day 1 inactive lever presses0.40.42.31.5-0.5-0.2-0.1-0.0-0.40.4-0.40.30.9
Intermitt. access day 15 inactive lever presses0.10.10.6-0.70.20.3-0.40.30.2-0.20.2-0.3-0.2
Intermitt. access escalation Index0.20.10.40.00.30.4-0.60.4-0.40.4-0.40.30.3
Intermittent access day 1 total infusions1.01.23.2-0.81.31.4-1.81.4-0.60.6-0.60.80.7
Intermittent access day 15 total infusions0.50.61.6-1.30.90.8-1.01.0-0.40.4-0.40.3-0.2
Intermittent access terminal intake (last 3 days)0.60.71.2-1.01.11.0-1.01.1-0.60.6-0.60.60.1
Intermittent access total infusions0.60.71.5-0.81.01.0-1.21.1-0.50.5-0.50.70.3
Intermittent access day 1 locomotion0.20.20.7-0.30.10.3-0.90.40.3-0.30.3-0.50.1
Intermittent access day 15 total locomotion0.50.62.4-1.50.30.0-0.10.00.6-0.60.6-1.0-1.1
Intermittent access total locomotion0.30.31.0-1.00.60.6-0.70.7-0.10.1-0.1-0.1-0.2
Intermittent access standard deviation0.20.20.8-0.1-0.2-0.40.9-0.30.2-0.20.2-0.1-0.6
Left kidney weight0.92.63.9-0.42.01.7-0.81.8-2.02.0-2.01.61.0
Right kidney weight0.71.93.20.01.61.4-0.91.5-1.51.5-1.51.81.2
Cocaine induced anxiety0.91.14.52.1-1.6-1.10.6-1.00.4-0.40.4-0.60.6
Post-drug Anxiety0.70.82.31.40.10.5-0.70.6-0.70.7-0.70.71.5
Baseline Anxiety1.71.83.1-1.11.81.8-1.61.7-1.01.0-1.01.20.8
Tail length6.519.728.2-0.35.05.3-4.15.2-4.44.4-4.44.74.3
Length with tail4.717.222.30.64.04.5-3.44.7-4.64.6-4.64.54.3
Length without tail0.10.30.50.7-0.20.1-0.10.5-0.50.5-0.50.70.6
Times rat made contact with spout0.20.20.60.80.00.20.10.4-0.50.5-0.50.50.6
Lifetime Intake0.70.81.4-1.21.21.1-1.21.2-0.50.5-0.50.60.1
Liver weight, left1.52.46.52.50.20.7-0.80.9-1.41.4-1.42.02.5
Liver weight, right3.45.611.53.00.71.4-1.11.9-2.62.6-2.62.73.4
Locomotor activity0.20.30.6-0.80.70.5-0.30.5-0.70.7-0.70.3-0.1
Locomotor testing distance1.22.03.4-1.41.81.5-1.11.6-1.61.6-1.61.30.3
Locomotor testing rearing1.92.94.0-0.21.71.7-1.31.9-2.02.0-2.02.01.3
Locomotion in novel chamber1.61.92.9-0.5-1.2-1.51.1-1.51.5-1.51.5-1.5-1.7
Locomotion in novel chamber post-restriction0.70.83.6-1.90.30.0-0.40.00.8-0.80.8-0.7-1.4
Fecal boli incidents, locomotor time 10.80.91.70.3-1.0-1.0-0.4-1.11.0-1.01.0-1.3-0.6
Change in fecal boli incidents, locomotor task0.10.10.40.40.10.10.10.10.2-0.20.20.60.4
Time >=10cm from walls, locomotor time 10.40.51.9-0.80.70.7-1.40.6-0.40.4-0.40.30.1
Bouts of movement, locomotor time 10.20.30.80.10.30.6-0.90.6-0.50.5-0.5-0.10.6
Total resting periods, locomotor time 10.10.10.30.0-0.3-0.1-0.4-0.00.1-0.10.1-0.60.0
Rest time, locomotor task time 10.10.10.8-0.1-0.00.2-0.90.20.2-0.20.2-0.00.3
Distance moved, locomotor task time 10.20.20.40.20.30.20.40.3-0.70.7-0.70.60.2
Vertical activity count, locomotor time 10.50.51.00.40.50.5-0.30.7-1.01.0-1.00.80.6
Time >=10cm from walls, locomotor time 23.23.46.0-0.72.02.2-2.52.2-1.51.5-1.52.11.6
Bouts of movement, locomotor time 22.93.25.61.21.31.7-1.51.8-2.02.0-2.01.52.4
Total resting periods, locomotor time 22.02.14.41.40.81.2-1.01.4-1.71.7-1.71.12.1
Rest time, locomotor task time 21.51.73.01.5-1.7-1.61.7-1.50.9-0.90.9-1.4-0.3
Distance moved, locomotor task time 22.32.74.2-1.42.01.9-1.72.0-1.51.5-1.51.80.6
Vertical activity count, locomotor time 22.02.12.70.21.31.5-1.51.6-1.61.6-1.61.71.4
Light reinforcement 12.03.79.91.6-2.2-2.33.1-2.21.4-1.41.4-1.6-1.0
Light reinforcement 22.93.97.2-0.9-1.4-1.92.7-2.11.9-1.91.9-2.0-2.5
Bone: marrow area1.63.56.0-0.22.02.2-2.52.2-1.81.8-1.81.91.7
Bone: maximum diameter2.34.26.7-1.02.42.4-2.62.4-2.02.0-2.01.91.4
Bone: maximum force0.61.03.10.60.50.8-1.81.0-0.90.9-0.90.91.3
Bone: maximum moment0.50.92.70.30.60.9-1.61.0-0.90.9-0.90.81.0
Mean time between licks in bursts8.912.415.2-0.63.83.9-3.63.8-3.93.9-3.93.53.0
Mean num. licks in bursts1.51.84.8-2.21.81.5-2.01.4-0.60.6-0.60.8-0.2
Cd content in liver0.20.20.80.9-0.5-0.40.8-0.40.3-0.30.3-0.30.2
Co content in liver3.64.36.9-0.42.12.4-2.62.4-2.02.0-2.02.01.9
Cu content in liver1.72.12.9-0.21.61.7-1.71.7-1.41.4-1.41.51.4
Fe content in liver0.20.20.60.50.20.4-0.80.5-0.30.3-0.30.40.7
K content in liver0.30.30.91.0-0.3-0.20.50.1-0.70.7-0.70.20.4
Mg content in liver0.10.10.1-0.20.20.10.20.2-0.40.4-0.40.0-0.1
Mn content in liver2.32.73.80.6-1.9-1.91.6-1.91.7-1.71.7-1.6-1.2
Na content in liver0.20.20.8-0.90.30.2-0.40.30.3-0.30.3-0.3-0.5
Rb content in liver0.50.61.3-0.70.91.0-1.11.0-0.50.5-0.50.50.3
Se content in liver2.12.65.01.8-2.2-1.91.5-1.71.5-1.51.5-1.5-0.4
Sr content in liver1.51.42.7-1.1-0.6-1.01.2-1.21.2-1.21.2-1.2-1.6
Zn content in liver0.91.04.6-2.11.50.9-0.70.8-0.40.4-0.40.2-0.8
Bone: minimum diameter2.75.06.70.62.02.2-2.02.4-2.62.6-2.62.42.3
Time in familiar zone, hab. session 10.20.20.3-0.20.50.50.00.3-0.50.5-0.50.50.3
Time in novel zone, hab. session 10.10.10.50.7-0.4-0.2-0.2-0.20.2-0.20.20.10.4
Total zone transitions, hab. session 10.40.61.3-1.1-0.2-0.30.5-0.40.9-0.90.9-0.8-1.1
Total locomotion distance, hab. session 11.21.73.11.50.60.80.10.9-1.61.6-1.61.61.8
Locomotion velocity, hab. session 11.01.52.41.30.50.70.20.9-1.61.6-1.61.31.5
Time in familiar zone, hab. session 22.32.34.5-0.81.81.8-2.11.6-1.21.2-1.21.81.2
Time in novel zone, hab. session 22.02.04.20.1-1.4-1.62.0-1.51.1-1.11.1-1.6-1.5
Total zone transitions, hab. session 20.70.95.3-2.31.10.8-0.50.7-0.10.1-0.10.1-0.9
Total locomotion distance, hab. session 23.14.06.90.71.61.7-0.71.9-2.62.6-2.62.42.0
Locomotion velocity, hab. session 23.24.37.50.91.61.8-0.71.9-2.72.7-2.72.52.1
Novel to familiar place preference ratio1.92.03.80.60.81.3-1.91.5-1.51.5-1.51.21.7
Novelty place preference2.02.03.60.60.81.3-1.91.5-1.51.5-1.51.21.7
Time in novel zone, NPP test2.32.44.50.41.01.4-2.11.6-1.61.6-1.61.41.7
Total zone transitions, NPP test0.71.02.8-1.3-0.4-0.71.1-0.70.8-0.80.8-1.2-1.7
Total locomotion distance, NPP test0.60.91.81.10.1-0.01.20.2-1.31.3-1.30.70.6
Locomotion velocity, NPP test0.60.82.41.2-0.2-0.31.6-0.2-1.11.1-1.10.50.4
Intraocular pressure2.12.95.7-1.1-1.0-1.20.5-1.42.4-2.42.4-1.5-1.8
Delta distance traveled before/after self-admin2.12.35.9-1.61.61.8-2.41.8-1.11.1-1.11.20.6
Delta ambulatory time before/after self-admin1.21.44.1-1.71.21.3-2.01.3-0.60.6-0.60.70.1
Parametrial fat weight0.61.34.90.9-1.0-1.32.2-1.20.6-0.60.6-1.2-0.8
Pavlov. Cond. lever latency0.60.81.50.8-1.1-1.21.2-1.20.7-0.70.7-0.5-0.4
Pavlov. Cond. magazine entry latency1.82.34.4-1.72.11.9-1.61.7-1.31.3-1.31.30.4
Pavlov. Cond. change in total contacts1.31.43.3-0.71.41.5-1.81.5-0.80.8-0.80.90.8
Pavlov. Cond. index score1.51.93.6-1.51.91.7-1.51.6-1.11.1-1.10.90.4
Pavlov. Cond. latency score1.51.93.4-1.41.81.7-1.71.7-1.11.1-1.11.00.5
Pavlov. Cond. lever contacts0.50.61.3-0.81.11.1-0.91.0-0.60.6-0.60.50.3
Pavlov. Cond. magazine entry number1.41.83.71.9-1.9-1.61.6-1.50.9-0.90.9-0.8-0.0
Pavlov. Cond. intertrial magazine entries0.20.30.90.9-0.9-0.60.4-0.40.4-0.40.4-0.30.1
Pavlov. Cond. lever-magazine prob. diff.1.11.32.7-1.41.71.5-1.31.4-0.80.8-0.80.70.2
Pavlov. Cond. response bias0.70.81.6-0.91.31.2-0.91.1-0.80.8-0.80.70.3
Pavlov. Cond. lever latency8.711.722.94.7-4.8-4.03.7-3.72.7-2.72.7-2.5-0.1
Pavlov. Cond. magazine entry latency1.11.37.8-2.81.40.7-0.20.5-0.30.3-0.30.0-1.5
Pavlov. Cond. change in total contacts6.79.222.2-4.74.33.6-3.13.3-2.22.2-2.22.0-0.3
Pavlov. Cond. index score5.87.518.0-4.23.93.1-2.72.9-2.12.1-2.11.8-0.4
Pavlov. Cond. latency score4.85.916.8-4.13.52.7-2.32.5-1.71.7-1.71.5-0.6
Pavlov. Cond. lever contacts9.012.423.8-4.84.94.2-3.93.9-2.82.8-2.82.60.2
Pavlov. Cond. magazine entry number2.22.613.03.6-2.2-1.51.2-1.20.6-0.60.6-0.41.3
Pavlov. Cond. intertrial magazine entries1.31.82.70.71.11.3-1.11.4-1.41.4-1.41.51.6
Pavlov. Cond. lever-magazine prob. diff.5.77.316.4-4.03.83.1-2.72.8-2.12.1-2.11.9-0.3
Pavlov. Cond. response bias8.411.425.0-5.04.73.9-3.63.6-2.52.5-2.52.3-0.2
Time in closed arm before self-admin0.80.95.9-2.40.60.4-0.80.20.2-0.20.2-0.2-1.2
Time in closed arm after self-admin0.40.40.70.6-0.9-0.70.4-0.80.5-0.50.5-0.6-0.0
Time in open arm before self-admin3.13.46.72.6-2.3-2.22.6-2.11.3-1.31.3-1.1-0.2
Time in open arm after self-admin0.20.20.40.50.40.4-0.30.4-0.40.4-0.40.50.6
Bone: periosteal estimation1.63.35.3-0.42.02.0-2.32.1-1.81.8-1.81.81.5
Bone: periosteal perimeter1.62.73.8-0.71.91.9-1.91.9-1.71.7-1.71.51.1
Bone: post-yield work0.20.31.0-0.30.50.5-1.00.6-0.40.4-0.40.70.3
Progressive ratio test 1 active lever presses0.00.00.1-0.20.10.1-0.20.20.1-0.10.1-0.3-0.0
Progressive ratio test 1 breakpoint0.00.00.1-0.10.20.3-0.20.30.0-0.00.0-0.10.2
Progressive ratio test 1 inactive lever presses0.10.10.4-0.30.30.4-0.60.5-0.20.2-0.20.10.1
Progressive ratio test 2 active lever presses0.60.71.4-0.40.91.0-1.21.2-0.60.6-0.60.50.6
Progressive ratio test 2 breakpoint0.80.91.7-0.41.01.1-1.31.3-0.80.8-0.80.70.7
Progressive ratio test 2 inactive lever presses0.20.20.8-0.80.40.4-0.90.5-0.00.0-0.00.1-0.1
Incentive Sensitization - Responses1.51.62.6-0.61.41.5-1.51.6-1.21.2-1.21.10.9
Incentive Sensitization - Breakpoint1.11.11.8-0.71.21.2-1.21.4-1.01.0-1.00.90.6
Sum of active levers in priming session hrs 5-60.00.00.1-0.40.00.00.2-0.0-0.10.1-0.10.2-0.2
Progressive ratio0.60.71.2-0.7-0.5-0.70.8-0.80.9-0.90.9-0.9-1.1
Food seeking constrained by brief footshock1.72.13.1-0.61.81.7-1.21.6-1.61.6-1.61.41.0
Seeking ratio, punishment vs. effort2.42.93.80.21.71.8-1.41.9-1.91.9-1.92.01.6
Retroperitoneal fat weight1.54.914.53.80.00.31.90.7-2.52.5-2.52.02.6
Reaction time number correct0.20.30.8-0.6-0.5-0.50.1-0.50.6-0.60.6-0.9-0.7
Reaction time mean minus median0.70.91.4-0.21.01.0-0.81.0-1.21.2-1.20.80.7
Reaction time mean minus median AUC0.50.61.0-0.50.90.8-1.00.9-0.90.9-0.90.70.4
Reaction time num false alarms0.81.06.32.5-1.0-0.60.6-0.4-0.40.4-0.40.21.2
Reaction time num false alarms AUC0.60.84.42.1-1.1-0.80.5-0.6-0.10.1-0.1-0.10.8
Reaction time trials correct on left0.20.30.8-0.6-0.5-0.50.1-0.50.6-0.60.6-0.9-0.7
Reaction time trials on left0.30.40.9-0.6-0.5-0.50.2-0.60.6-0.60.6-0.9-0.8
Reaction time mean0.81.14.62.1-0.4-0.00.00.2-1.01.0-1.01.01.5
Reaction time mean AUC0.60.84.32.1-0.6-0.20.10.0-0.60.6-0.60.71.3
Median of all reaction times0.81.05.82.4-0.9-0.40.3-0.2-0.60.6-0.60.81.4
Reaction time omissions0.20.31.11.0-0.6-0.61.0-0.4-0.30.3-0.3-0.20.1
Reaction time false alarm rate0.60.85.22.3-0.9-0.70.6-0.5-0.30.3-0.30.21.0
Reaction time premature initiation rate2.12.94.3-0.32.11.9-1.21.8-1.91.9-1.91.81.4
Reaction time premature initiations0.81.12.1-0.61.41.3-0.81.1-1.21.2-1.20.80.6
Std. dev. reaction times1.52.13.21.10.91.2-1.01.3-1.71.7-1.71.61.8
Reaction time trials completed0.30.40.9-0.6-0.5-0.50.2-0.60.6-0.60.6-0.9-0.8
Reaction time trials AUC0.10.20.5-0.5-0.3-0.40.1-0.40.3-0.30.3-0.7-0.5
Run reversals in cocaine runway, females1.81.83.20.81.21.00.41.1-1.81.8-1.81.51.2
Run reversals in cocaine runway, males0.40.30.60.3-0.7-0.60.3-0.60.8-0.80.8-0.5-0.3
Latency to leave start box in cocaine runway0.60.61.91.4-0.8-0.71.1-0.70.5-0.50.5-0.80.3
Latency to leave start box in cocaine runway, F0.40.42.41.6-0.3-0.00.5-0.0-0.20.2-0.20.11.0
Latency to leave start box in cocaine runway, M1.61.63.00.2-1.1-1.21.0-1.31.5-1.51.5-1.7-0.9
Std. dev. time between licks in bursts4.25.06.80.52.12.2-1.82.3-2.62.6-2.62.42.3
Total sessions with >9 infusions1.01.16.3-2.51.20.8-0.70.70.3-0.30.3-0.1-1.1
Short access day 1 total inactive lever presses0.10.10.40.6-0.30.1-0.70.3-0.00.0-0.0-0.30.5
Short access day 10 total inactive lever presses0.30.40.80.8-0.9-0.80.4-0.70.4-0.40.4-0.6-0.1
Short access day 1 total infusions1.31.42.5-1.31.61.5-1.61.5-0.80.8-0.80.90.4
Short access day 10 total infusions1.01.22.1-1.11.41.4-1.21.4-0.80.8-0.80.90.4
Short access total infusions0.70.81.7-1.11.31.2-1.11.2-0.60.6-0.60.70.2
Short access day 1 locomotion1.31.43.2-1.8-0.1-0.4-0.1-0.51.4-1.41.4-1.3-1.6
Short access day 10 total locomotion0.10.10.2-0.30.20.10.40.2-0.30.3-0.3-0.3-0.3
Short access total locomotion0.20.20.4-0.6-0.0-0.10.1-0.00.5-0.50.5-0.6-0.6
One hour access (0.3 mA shock)0.40.51.2-1.11.00.7-0.60.8-0.60.6-0.60.6-0.2
Compulsive drug intake1.41.52.40.0-1.2-1.30.7-1.31.5-1.51.5-1.2-1.0
One hour access (shock baseline)1.41.72.4-0.81.51.4-1.21.5-1.41.4-1.41.40.6
Social response proportion0.40.41.31.1-0.2-0.20.8-0.1-0.80.8-0.8-0.10.5
Social responses1.62.14.41.60.50.7-0.11.0-2.12.1-2.10.61.7
Social time1.21.63.31.3-1.7-1.41.7-1.30.6-0.60.6-1.8-0.3
Soleus weight0.72.13.41.80.70.8-0.21.0-1.91.9-1.91.31.8
Bone: stiffness1.93.06.11.80.61.2-2.01.5-1.71.7-1.71.72.5
Tibialis anterior weight0.51.52.20.51.01.1-1.11.2-1.51.5-1.51.41.3
Time to tail flick, vehicle, before self-admin0.20.20.4-0.50.30.4-0.30.6-0.40.4-0.40.1-0.0
Time to tail flick, vehicle, after self-admin0.90.93.9-2.01.00.9-1.50.80.3-0.30.3-0.2-0.5
Time to tail flick, test, before self-admin1.21.22.1-0.81.41.4-1.31.5-0.80.8-0.81.00.6
Time to tail flick, test, after self-admin3.43.54.40.11.92.1-1.82.1-2.02.0-2.02.01.9
Delta time to tail flick, vehicle, before/after SA0.50.51.5-1.20.20.0-0.6-0.20.8-0.80.8-0.6-0.8
Delta time to tail flick, test, before/after SA0.10.10.40.6-0.2-0.20.6-0.2-0.30.3-0.30.20.2
Tibia length0.41.24.5-1.81.01.1-2.11.1-0.30.3-0.30.3-0.2
Ambulatory time before self-admin1.11.21.91.0-1.1-1.21.4-1.31.1-1.11.1-1.0-0.3
Ambulatory time after self-admin0.30.31.0-1.0-0.1-0.1-0.3-0.20.6-0.60.6-0.5-0.6
Bone: tissue strength2.82.74.0-0.8-1.4-1.71.5-1.71.8-1.81.8-1.8-2.0
Total heroin consumption0.40.41.0-1.00.70.5-0.30.5-0.80.8-0.80.6-0.2
Bone: trabecular number1.42.22.90.2-1.6-1.61.4-1.51.7-1.71.7-1.7-1.2
Bone: trabecular spacing0.20.31.6-1.30.4-0.00.4-0.10.1-0.10.1-0.3-1.0
Bone: trabecular thickness1.21.53.31.10.51.0-1.41.2-1.11.1-1.11.31.8
Bone: trabecular tissue density3.65.010.72.80.71.4-1.31.8-2.52.5-2.52.33.3
Water consumed over 24 hours0.40.50.90.5-1.0-0.80.7-0.70.8-0.80.8-0.5-0.4
Number of responses in last shaping day0.70.71.60.40.60.9-1.31.1-0.80.8-0.80.51.1