Hub : Traits

Time in closed arm after self-admin

Time spent in the closed arm during the second time point of elevated plus maze after self admin

Tags: Behavior · Heroin · Elevated plus maze

Project: u01_peter_kalivas

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr8	117463629	118343328	1	1	5.76e-16	1.24e-01	1.00e+00	Mst1
2	chr9	31552495	32504457	1	1	1.27e-07	9.05e-02	1.12e-05	LOC134480352
3	chr9	83390749	84777604	1	1	0.00e+00	2.66e-01	1.00e+00	Retreg2
4	chr17	61510864	62906219	1	1	1.46e-15	4.60e-02	5.55e-03	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	434.48	2	1	25	0	1.00e+00	LOC134480352 Retreg2
BMI without tail	19084.19	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Body weight	6.47	2	1	25	0	1.00e+00	Mst1 Retreg2
Epididymis fat weight	12105.07	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Glucose	227.08	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Heart weight	3065.65	1	1	25	0	1.00e+00	Retreg2
Left kidney weight	18350.02	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Right kidney weight	10106.66	4	3	75	-0.98	1.64e-02	Ccny LOC134480352 Mst1 Retreg2
Tail length	14460.63	2	1	25	0	1.00e+00	Mst1 Retreg2
Length with tail	747.9	2	2	50	0	1.00e+00	Mst1 Retreg2
Length without tail	11815.07	4	2	50	-0.98	1.57e-02	Ccny LOC134480352 Mst1 Retreg2
Liver weight, left	1171.95	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Liver weight, right	32.43	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Parametrial fat weight	94.06	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Retroperitoneal fat weight	1324.97	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Intraocular pressure	5195.84	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Extensor digitorum longus weight	362.6	3	1	25	0	1.00e+00	LOC134480352 Mst1 Retreg2
Soleus weight	11.61	2	1	25	0	1.00e+00	Mst1 Retreg2
Tibialis anterior weight	580.28	2	1	25	0	1.00e+00	Mst1 Retreg2
Tibia length	265.15	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Number of licking bursts	67424.86	1	1	25	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	11843.69	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Times rat made contact with spout	71.66	1	1	25	0	1.00e+00	Retreg2
Mean time between licks in bursts	55818.16	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Mean num. licks in bursts	56750.08	1	1	25	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	9924.42	3	1	25	0	1.00e+00	LOC134480352 Mst1 Retreg2
Water consumed over 24 hours	11394.32	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging indifference point 0 sec	19591.07	2	1	25	0	1.00e+00	Mst1 Retreg2
Patch foraging indifference point AUC	16749.7	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Indifference point function ln k	18611.12	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Indifference point function log k	18611.12	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 0 sec	20977.37	2	1	25	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 12 sec	801.08	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 18 sec	13492.82	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 24 sec	18716.27	4	2	50	0.98	2.24e-02	Ccny LOC134480352 Mst1 Retreg2
Patch foraging total patch changes 6 sec	1953.26	4	1	25	0.98	1.67e-02	Ccny LOC134480352 Mst1 Retreg2
Patch foraging time to switch 0 sec	33247.44	2	1	25	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 0 sec	30216.22	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Patch foraging water rate 12 sec	17670	4	2	50	-0.98	2.43e-02	Ccny LOC134480352 Mst1 Retreg2
Patch foraging water rate 18 sec	11250.13	3	1	25	0	1.00e+00	LOC134480352 Mst1 Retreg2
Patch foraging water rate 24 sec	523.92	2	1	25	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 6 sec	430.39	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotor activity	22	2	1	25	0	1.00e+00	Ccny Mst1
Locomotor testing distance	6932.81	4	3	75	-0.97	3.11e-02	Ccny LOC134480352 Mst1 Retreg2
Locomotor testing rearing	31715.18	2	2	50	0	1.00e+00	Mst1 Retreg2
Light reinforcement 1	22114.5	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Light reinforcement 2	12279.37	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time number correct	21162.41	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Reaction time mean minus median	59976.97	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time mean minus median AUC	62004.19	2	2	50	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms	7685.9	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms AUC	11677.34	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time trials correct on left	21162.41	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Reaction time trials on left	20300.83	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Reaction time mean	29724.21	1	1	25	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	25	0	1.00e+00	Retreg2
Median of all reaction times	7893.84	1	1	25	0	1.00e+00	Retreg2
Reaction time omissions	4184.97	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time false alarm rate	111.7	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time premature initiation rate	9733.76	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	25	0	1.00e+00	Retreg2
Std. dev. reaction times	30437.76	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time trials completed	20300.83	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Reaction time trials AUC	20717.03	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Social response proportion	4397.95	2	1	25	0	1.00e+00	Mst1 Retreg2
Social responses	323.35	4	1	25	-0.99	1.46e-02	Ccny LOC134480352 Mst1 Retreg2
Social time	3887.64	3	1	25	0	1.00e+00	LOC134480352 Mst1 Retreg2
Conditioned locomotion	1400.08	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	25	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	25	0	1.00e+00	Retreg2
Saline control response	1639.18	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	7271.32	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	28713.86	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	1165.18	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	5466.41	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	1963.38	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever reinforcers received	243.91	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	1278.33	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry latency	6738.25	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	39811.91	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	6407.33	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	8109.24	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	2689.72	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	2097.69	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	17558.57	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	5938.34	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	641.31	2	2	50	0	1.00e+00	Mst1 Retreg2
Conditioned reinforcement - actives	33603.23	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Conditioned reinforcement - inactives	21672.46	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Conditioned locomotion	2591.76	4	1	25	0.97	2.70e-02	Ccny LOC134480352 Mst1 Retreg2
Intermittent access intake day 1-15 change	42631.78	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Intermittent access intake escalation	63041.23	2	2	50	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	12071.47	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Intermitt. access day 1 inactive lever presses	60229.82	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Intermitt. access day 15 inactive lever presses	123608.2	1	1	25	0	1.00e+00	Retreg2
Intermitt. access escalation Index	31136.33	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Intermittent access day 1 total infusions	33063.01	2	1	25	0	1.00e+00	Mst1 Retreg2
Intermittent access day 15 total infusions	48731.91	1	1	25	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	25	0	1.00e+00	Retreg2
Intermittent access total infusions	93.49	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 locomotion	17487.55	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total locomotion	42786.58	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	62.99	2	1	25	0	1.00e+00	Mst1 Retreg2
Intermittent access standard deviation	38004.24	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Cocaine induced anxiety	34553.78	2	1	25	0	1.00e+00	Ccny Retreg2
Post-drug Anxiety	2380.44	2	1	25	0	1.00e+00	Mst1 Retreg2
Baseline Anxiety	16763.76	2	1	25	0	1.00e+00	Ccny Retreg2
Lifetime Intake	834.23	2	1	25	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Responses	35678.36	2	1	25	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Breakpoint	27641.32	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 active lever presses	16000.1	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 breakpoint	15155.7	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 inactive lever presses	31120.43	2	2	50	0	1.00e+00	Mst1 Retreg2
Progressive ratio test 2 active lever presses	7640.52	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 breakpoint	4281.49	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 inactive lever presses	24172.02	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Total sessions with >9 infusions	678.23	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Short access day 1 total inactive lever presses	9878.73	4	2	50	-0.98	1.95e-02	Ccny LOC134480352 Mst1 Retreg2
Short access day 10 total inactive lever presses	46316.52	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Short access day 1 total infusions	12825.11	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Short access day 10 total infusions	11366.61	2	2	50	0	1.00e+00	Mst1 Retreg2
Short access total infusions	4403.04	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	8274.49	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Short access day 10 total locomotion	44094.34	2	1	25	0	1.00e+00	Mst1 Retreg2
Short access total locomotion	6241.02	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Compulsive drug intake	6234.51	3	1	25	0	1.00e+00	LOC134480352 Mst1 Retreg2
One hour access (0.3 mA shock)	1168.72	2	1	25	0	1.00e+00	Ccny Retreg2
One hour access (shock baseline)	54988.81	1	1	25	0	1.00e+00	Retreg2
Number of responses in last shaping day	3414.69	4	1	25	0.98	1.72e-02	Ccny LOC134480352 Mst1 Retreg2
Context. condit. distance diff. score	212.47	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 1	1768.4	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Locomotion distance, session 1	516.6	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	1110.36	2	2	50	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	174.93	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Locomotion velocity, session 3	507.49	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	691.91	2	1	25	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving duration, day 3	1446.08	2	1	25	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	210.64	2	2	50	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	507.07	2	2	50	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving bouts, day 7	1261.07	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Stereotopy head waving duration, day 7	1062.08	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Locomotion velocity, session 8	409.23	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	1889.61	2	2	50	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	686.98	3	1	25	0	1.00e+00	LOC134480352 Mst1 Retreg2
Condit. Reinf. active minus inactive responses	957.65	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	2347.96	2	1	25	0	1.00e+00	Mst1 Retreg2
Incentive salience index mean	1780.77	2	1	25	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	2666.81	2	2	50	0	1.00e+00	Mst1 Retreg2
Time in familiar zone, hab. session 1	5593.23	2	1	25	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 1	4629.95	2	2	50	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	429.72	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	199.56	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	2966.16	2	2	50	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	3208.33	2	2	50	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	38.53	2	1	25	0	1.00e+00	Mst1 Retreg2
Total locomotion distance, hab. session 2	13.16	3	1	25	0	1.00e+00	LOC134480352 Mst1 Retreg2
Locomotion velocity, hab. session 2	20.41	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Novel to familiar place preference ratio	5121.06	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Novelty place preference	7474.7	2	1	25	0	1.00e+00	Mst1 Retreg2
Time in novel zone, NPP test	5350.34	2	1	25	0	1.00e+00	Mst1 Retreg2
Total zone transitions, NPP test	1935.62	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	851.42	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Locomotion velocity, NPP test	323.58	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Pavlov. Cond. lever latency	276.98	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	522.83	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. index score	214.07	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	224.45	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	372.95	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	250.94	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	82.71	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	223.77	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	303.26	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: apparent density	5461.77	1	1	25	0	1.00e+00	Retreg2
Bone surface	3109.3	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone volume	4317.38	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	838.02	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical apparent density	12020.36	1	1	25	0	1.00e+00	Retreg2
Bone: cortical area	1558.8	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Bone: cortical porosity	220.21	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical porosity	1113.18	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	232.49	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical thickness	1488.54	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical tissue density	6503.84	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: elastic displacement	7604.03	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	195.81	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: endosteal estimation	4459.49	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: endosteal perimeter	5936.33	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: final force	564.42	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Bone: final moment	101.47	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Bone: marrow area	4718.94	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: maximum diameter	3067.59	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: maximum force	2930.77	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Bone: maximum moment	2026.27	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Bone: minimum diameter	2061.38	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	4919.52	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: periosteal perimeter	5722.93	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: post-yield work	6843.13	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	3041.54	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Bone: tissue strength	2995.95	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	10739.78	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular spacing	3991.76	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: trabecular thickness	4257.4	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	4861.46	3	2	50	0	1.00e+00	LOC134480352 Mst1 Retreg2
Breakpoint value in progressive ratio session	18809.48	2	1	25	0	1.00e+00	Mst1 Retreg2
Distance traveled before self-admin	16850.59	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Distance traveled after self-admin	16247.09	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	100.28	4	2	50	0.88	1.17e-01	Ccny LOC134480352 Mst1 Retreg2
Delta time in open arm before/after self-admin	5049.67	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Diff in mean of infusions in LGA sessions	18336.8	2	2	50	0	1.00e+00	Mst1 Retreg2
Extinction: sum of active levers before priming	9495.75	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Active lever presses in extinction session 6	272.24	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Delta distance traveled before/after self-admin	1480.05	2	1	25	0	1.00e+00	Ccny Retreg2
Delta ambulatory time before/after self-admin	15428.86	2	1	25	0	1.00e+00	Ccny Retreg2
Time in closed arm before self-admin	8974	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Time in open arm before self-admin	2198.78	4	2	50	-0.98	2.46e-02	Ccny LOC134480352 Mst1 Retreg2
Time in open arm after self-admin	143.5	4	2	50	0.85	1.55e-01	Ccny LOC134480352 Mst1 Retreg2
Sum of active levers in priming session hrs 5-6	978.69	1	1	25	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	4498.29	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Time to tail flick, vehicle, after self-admin	21076.92	2	1	25	0	1.00e+00	Ccny Retreg2
Time to tail flick, test, before self-admin	4073.42	2	1	25	0	1.00e+00	Mst1 Retreg2
Time to tail flick, test, after self-admin	476.57	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Delta time to tail flick, vehicle, before/after SA	3305.45	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Delta time to tail flick, test, before/after SA	7847.8	2	1	25	0	1.00e+00	Mst1 Retreg2
Ambulatory time before self-admin	39445.74	2	1	25	0	1.00e+00	Ccny Retreg2
Ambulatory time after self-admin	8880.01	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Total heroin consumption	134.58	2	2	50	0	1.00e+00	Ccny Retreg2
Area under the delay curve	24791.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	10986.22	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	16227.16	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	212.14	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Delay disc. indifference point, 8s delay	16685.13	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Delay discount exponential model param	16922.54	1	1	25	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	25	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	25	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	2856.56	2	2	50	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	4346.77	3	1	25	0	1.00e+00	Ccny LOC134480352 Retreg2
Bouts of movement, locomotor time 1	5409.06	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	1407.78	2	1	25	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	22349.64	1	1	25	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	34413.79	2	1	25	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	35582.77	2	1	25	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	27351.99	3	2	50	0	1.00e+00	Ccny LOC134480352 Retreg2
Total resting periods, locomotor time 2	33022.87	3	2	50	0	1.00e+00	Ccny LOC134480352 Retreg2
Rest time, locomotor task time 2	25503.09	1	1	25	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	4250.65	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	26786.04	2	1	25	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	35403.57	2	2	50	0	1.00e+00	Ccny Retreg2
Seeking ratio, delayed vs. immediate footshock	6729.38	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	1954.56	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber post-restriction	32713.51	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio	33954	2	2	50	0	1.00e+00	Ccny Retreg2
Food seeking constrained by brief footshock	1875.34	1	1	25	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	20643.93	2	1	25	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	25	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	7664.74	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	8153.9	2	1	25	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	7166.92	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	880.56	2	2	50	0	1.00e+00	Ccny Retreg2
Co content in liver	1133.25	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	24.01	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Fe content in liver	1344.53	1	1	25	0	1.00e+00	Retreg2
K content in liver	766.86	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Mg content in liver	3017.36	2	1	25	0	1.00e+00	LOC134480352 Retreg2
Mn content in liver	1009.39	1	1	25	0	1.00e+00	Retreg2
Na content in liver	4018.36	1	1	25	0	1.00e+00	Retreg2
Rb content in liver	87.87	1	1	25	0	1.00e+00	Retreg2
Se content in liver	9.6	1	0	0	0	1.00e+00	LOC134480352
Zn content in liver	3745.55	1	1	25	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.04
Adipose	alternative TSS	0	0	1.09
Adipose	gene expression	0	0	1.03
Adipose	isoform ratio	0	0	1.07
Adipose	intron excision ratio	0	0	0.93
Adipose	mRNA stability	0	0	1.05
BLA	alternative polyA	0	0	1.04
BLA	alternative TSS	0	0	1.06
BLA	gene expression	0	0	1.06
BLA	isoform ratio	0	0	1.05
BLA	intron excision ratio	0	0	1.04
BLA	mRNA stability	0	0	1.07
Brain	alternative polyA	0	0	1.06
Brain	alternative TSS	0	0	1.1
Brain	gene expression	1	0	1.05
Brain	isoform ratio	0	0	1.07
Brain	intron excision ratio	0	0	1.06
Brain	mRNA stability	0	0	1.08
Eye	alternative polyA	0	0	1.08
Eye	alternative TSS	0	0	1.13
Eye	gene expression	0	0	1.07
Eye	isoform ratio	0	0	1.12
Eye	intron excision ratio	0	0	1.01
Eye	mRNA stability	0	0	1.15
IC	alternative polyA	0	0	1.06
IC	alternative TSS	0	0	1.03
IC	gene expression	0	0	1.04
IC	isoform ratio	0	0	1.07
IC	intron excision ratio	0	0	1.06
IC	mRNA stability	0	0	1.05
IL	alternative polyA	0	0	1.12
IL	alternative TSS	0	0	1.09
IL	gene expression	0	0	1.05
IL	isoform ratio	0	0	1.08
IL	intron excision ratio	0	0	1.07
IL	mRNA stability	0	0	1.1
LHb	alternative polyA	0	0	1.07
LHb	alternative TSS	0	0	0.98
LHb	gene expression	0	0	1.01
LHb	isoform ratio	0	0	1.03
LHb	intron excision ratio	0	0	0.96
LHb	mRNA stability	0	0	1.1
Liver	alternative polyA	0	0	1.1
Liver	alternative TSS	0	0	1
Liver	gene expression	0	0	1.05
Liver	isoform ratio	1	0	1.06
Liver	intron excision ratio	0	0	0.99
Liver	mRNA stability	0	0	1.06
NAcc	alternative polyA	1	0	2.46
NAcc	alternative TSS	0	0	1.08
NAcc	gene expression	0	0	1.05
NAcc	isoform ratio	0	0	1.06
NAcc	intron excision ratio	0	0	1.02
NAcc	mRNA stability	0	0	1.07
OFC	alternative polyA	0	0	1.04
OFC	alternative TSS	0	0	0.95
OFC	gene expression	0	0	1.05
OFC	isoform ratio	0	0	1.09
OFC	intron excision ratio	0	0	0.93
OFC	mRNA stability	0	0	1.06
PL	alternative polyA	0	0	1.12
PL	alternative TSS	0	0	1.02
PL	gene expression	0	0	1.05
PL	isoform ratio	0	0	1.06
PL	intron excision ratio	0	0	1.02
PL	mRNA stability	0	0	1.08
pVTA	alternative polyA	0	0	1.02
pVTA	alternative TSS	0	0	1.07
pVTA	gene expression	1	0	1.04
pVTA	isoform ratio	0	0	1.05
pVTA	intron excision ratio	0	0	1.07
pVTA	mRNA stability	0	0	1.1
RMTg	alternative polyA	0	0	0.92
RMTg	alternative TSS	0	0	0.95
RMTg	gene expression	0	0	1.01
RMTg	isoform ratio	0	0	1.24
RMTg	intron excision ratio	0	0	0.9
RMTg	mRNA stability	0	0	1.04