Hub : Genes

Rab6a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA isoform ratio NM_053366.2 0.06 0.05 4.2e-03 0.02 0.04 0.04 0.03 2.0e-02 3.8e-03 2.9e-03 6.5e-03
2 BLA isoform ratio NM_001414455.1 0.05 0.04 8.9e-03 0.02 0.03 0.04 0.03 2.8e-02 9.3e-03 5.7e-03 1.3e-02
3 PL isoform ratio NM_001414455.1 0.03 0.02 1.5e-03 0 0.01 0.02 0.01 1.3e-01 7.7e-03 2.7e-03 2.1e-02
4 PL isoform ratio NM_053366.2 0.03 0.03 4.2e-04 0.02 0.02 0.03 0.02 1.7e-03 2.1e-03 5.4e-04 4.7e-03
5 PL intron excision ratio chr1_164394215_164396320 0.02 0.02 7.4e-03 0.01 0.02 0.01 0.01 1.5e-02 6.1e-03 3.0e-02 1.2e-02
6 PL intron excision ratio chr1_164394387_164396320 0.02 0.02 7.9e-03 0.01 0.02 0.01 0.01 1.4e-02 5.8e-03 2.0e-02 1.3e-02
7 Adipose mRNA stability Rab6a 0.03 0.02 1.3e-03 0.02 0.02 0.02 0.01 2.3e-03 2.0e-03 3.2e-03 7.2e-03
8 PL mRNA stability Rab6a 0.03 0.02 1.9e-03 0.01 0.03 0.01 0.01 1.3e-02 7.8e-04 3.2e-02 1.3e-02
9 NAcc mRNA stability Rab6a 0.04 0.03 6.5e-05 0.01 0.02 0.02 0.02 4.0e-03 1.9e-04 2.2e-04 3.1e-04
10 pVTA mRNA stability Rab6a 0.13 0.11 1.2e-04 0.05 0.06 0.04 0.05 1.4e-04 3.3e-05 5.2e-04 6.5e-05
11 Brain mRNA stability Rab6a 0.21 0.1 1.1e-14 0.13 0.16 0.15 0.15 1.9e-12 1.0e-14 1.3e-13 4.5e-14
12 NAcc isoform ratio NM_053366.2 0.02 0.01 3.7e-03 0.02 0.01 0.01 0.01 2.3e-04 4.4e-03 2.5e-03 1.8e-03
13 OFC mRNA stability Rab6a 0.22 0.13 2.3e-04 0.14 0.12 0.07 0.1 3.3e-04 9.2e-04 8.1e-03 2.5e-03
14 Liver mRNA stability Rab6a 0.18 0.1 1.6e-15 0.11 0.11 0.11 0.11 1.5e-12 4.7e-12 5.6e-12 7.2e-12
15 pVTA gene expression Rab6a 0.06 0.04 6.4e-05 0.03 0.04 0.03 0.02 9.9e-04 3.7e-04 1.5e-03 4.2e-03
16 BLA gene expression Rab6a 0.13 0.08 6.4e-04 0.04 0.04 0.04 0.04 5.9e-03 3.1e-03 4.7e-03 3.7e-03
17 PL gene expression Rab6a 0.11 0.07 6.7e-08 0.07 0.06 0.06 0.06 1.1e-07 6.1e-07 3.0e-07 9.2e-07
18 Brain gene expression Rab6a 0.38 0.19 0.0e+00 0.19 0.2 0.21 0.2 3.0e-17 1.8e-18 4.6e-19 3.7e-18
19 NAcc gene expression Rab6a 0.17 0.08 0.0e+00 0.15 0.21 0.21 0.21 1.5e-22 1.7e-31 8.2e-31 8.8e-31
20 OFC gene expression Rab6a 0.33 0.16 3.0e-06 0.07 0.18 0.14 0.14 1.0e-02 5.3e-05 3.9e-04 4.3e-04
21 IC gene expression Rab6a 0.33 0.13 1.1e-09 0.17 0.17 0.19 0.19 1.3e-07 8.6e-08 1.7e-08 2.9e-08
22 IL gene expression Rab6a 0.54 0.17 4.9e-09 0.1 0.23 0.19 0.21 2.3e-03 3.6e-06 3.2e-05 1.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.20.41.1-0.60.70.1-0.10.1-0.1-0.1-0.00.90.90.90.2-0.1-0.0-0.3-0.91.00.5-0.6-0.60.8-0.8
Area under the delay curve0.10.10.2-0.40.30.4-0.30.3-0.3-0.4-0.3-0.1-0.0-0.1-0.30.40.40.40.2-0.3-0.50.40.4-0.20.3
BMI with tail0.82.76.50.1-0.21.4-1.40.9-0.9-1.0-1.1-1.6-1.7-1.7-1.51.31.21.72.0-2.2-2.52.02.1-2.42.2
BMI without tail0.63.47.91.2-1.30.5-0.70.2-0.3-0.4-0.6-2.5-2.6-2.6-1.11.00.91.52.8-2.8-2.62.12.2-2.72.6
Body weight1.14.910.41.2-1.30.8-1.00.9-1.0-1.1-1.3-2.5-2.7-2.8-1.91.71.82.33.1-3.2-2.62.82.9-3.23.2
Weight adjusted by age0.10.41.30.4-0.40.1-0.10.1-0.1-0.1-0.2-0.8-0.8-0.9-0.40.20.40.50.9-0.9-1.10.70.7-0.80.9
Bone surface0.30.61.41.2-1.2-1.11.0-0.90.90.90.9-0.9-0.8-0.80.7-0.7-0.6-0.50.6-0.6-0.5-0.2-0.20.00.1
Bone volume0.10.30.60.8-0.8-0.80.8-0.60.60.60.6-0.5-0.4-0.50.5-0.5-0.4-0.40.3-0.2-0.3-0.2-0.20.20.0
Breakpoint value in progressive ratio session0.50.92.6-1.21.20.7-0.80.6-0.6-0.6-0.41.61.61.5-0.10.20.2-0.1-1.41.31.2-0.5-0.61.0-1.0
Number of licking bursts1.44.38.1-2.42.42.6-2.62.8-2.8-2.8-2.81.41.21.1-2.62.72.52.3-0.40.1-0.41.71.7-1.11.0
Context. condit. distance diff. score2.12.54.91.6-1.5-2.22.2-2.12.12.12.1-0.8-0.5-0.52.0-2.0-2.0-1.8-0.00.30.8-1.5-1.41.2-1.0
Locomotion velocity, session 10.60.71.5-0.90.90.2-0.2-0.10.10.10.21.11.21.20.4-0.4-0.4-0.7-1.21.21.0-0.9-0.91.1-1.1
Locomotion distance, session 10.91.22.01.0-1.0-1.31.3-1.41.41.41.4-0.2-0.1-0.01.4-1.4-1.4-1.4-0.30.50.9-1.2-1.11.0-0.9
Locomotion velocity, session 20.10.10.60.7-0.7-0.50.5-0.20.20.20.2-0.4-0.4-0.40.1-0.1-0.0-0.10.3-0.3-0.10.10.1-0.10.2
Locomotion distance, session 20.40.61.60.8-0.8-1.21.3-0.90.90.90.9-0.4-0.2-0.30.9-0.9-1.0-0.80.00.10.3-0.6-0.60.6-0.4
Locomotion velocity, session 31.01.12.10.9-0.8-0.90.7-1.21.21.21.30.10.30.21.4-1.4-1.4-1.3-0.60.81.3-1.2-1.21.0-1.1
Locomotion distance, session 31.61.83.20.7-0.7-1.41.4-1.61.61.61.70.10.30.41.8-1.8-1.7-1.8-0.71.01.0-1.7-1.61.5-1.4
Stereotopy head waving bouts, day 30.50.61.20.00.00.6-0.71.0-1.0-1.0-1.0-0.1-0.2-0.3-1.11.11.01.10.5-0.6-0.31.11.0-0.90.9
Stereotopy head waving duration, day 30.10.20.50.5-0.4-0.50.5-0.50.50.50.5-0.1-0.0-0.00.5-0.5-0.7-0.5-0.10.20.5-0.4-0.40.3-0.3
Locomotion velocity, session 70.20.20.6-0.40.5-0.10.20.2-0.2-0.2-0.10.80.70.8-0.00.0-0.1-0.2-0.70.70.3-0.4-0.40.7-0.6
Locomotion distance, session 70.10.10.3-0.50.50.00.20.5-0.5-0.5-0.50.30.30.3-0.40.40.40.4-0.20.1-0.40.30.20.20.1
Stereotopy head waving bouts, day 72.32.74.82.0-2.0-2.11.9-2.22.22.22.2-0.9-0.7-0.62.0-2.0-2.0-1.90.10.20.7-1.5-1.40.9-0.9
Stereotopy head waving duration, day 72.12.65.02.0-2.0-1.91.7-2.22.22.22.2-1.3-1.1-1.01.9-2.0-2.0-1.70.6-0.30.2-1.2-1.10.5-0.5
Locomotion velocity, session 80.70.92.11.5-1.4-1.41.3-1.11.11.11.1-0.5-0.4-0.41.0-1.0-1.1-0.90.2-0.00.7-0.7-0.60.5-0.4
Locomotion distance, session 81.92.75.62.0-1.9-2.42.3-2.22.12.12.1-1.1-0.9-0.91.9-1.9-2.1-1.70.4-0.10.5-1.2-1.20.9-0.7
Degree of sensitization distance2.22.44.6-0.10.10.8-0.71.5-1.6-1.6-1.7-0.8-1.0-1.0-1.91.91.82.11.4-1.6-1.72.12.1-1.82.0
Degree of sensitization stereotypy4.14.68.82.5-2.5-2.72.5-3.03.03.02.9-1.4-1.1-1.12.7-2.7-2.6-2.50.4-0.00.5-1.8-1.71.1-1.0
Conditioned locomotion0.30.41.6-0.30.30.2-0.3-0.00.00.00.20.80.90.70.4-0.4-0.4-0.4-0.90.81.3-0.5-0.70.7-0.8
Cocaine response after cond. corrected1.42.24.3-1.51.42.0-2.11.8-1.8-1.8-1.80.50.30.3-1.81.82.01.70.2-0.4-1.01.41.4-1.21.0
Cocaine response after cond. not corrected0.40.61.3-1.11.01.1-1.20.8-0.8-0.8-0.90.30.20.3-0.80.81.00.7-0.0-0.0-0.70.50.6-0.50.4
Cocaine response before conditioning2.12.55.01.0-1.0-1.71.6-2.12.12.12.1-0.4-0.20.02.1-2.1-2.2-2.1-0.50.70.7-1.9-1.71.3-1.3
Saline control response1.21.65.92.4-2.3-1.71.6-1.21.21.21.1-1.7-1.6-1.60.8-0.8-0.6-0.51.3-1.1-0.50.10.1-0.50.6
Bone: connectivity density0.30.51.1-0.40.4-0.10.2-0.40.40.40.40.70.70.90.7-0.6-0.6-0.8-0.91.00.5-1.0-0.91.0-1.0
Bone: cortical apparent density1.22.03.8-1.31.41.9-1.91.9-1.9-1.9-1.90.90.80.7-1.61.71.91.6-0.30.1-0.21.21.1-0.70.7
Bone: cortical area0.20.30.80.8-0.8-0.1-0.1-0.00.0-0.0-0.0-0.8-0.8-0.9-0.20.20.30.40.9-0.9-0.60.60.6-0.70.7
Bone: cortical porosity0.91.01.80.1-0.2-0.80.7-1.21.21.21.20.20.40.41.2-1.3-1.4-1.3-0.70.80.7-1.3-1.31.1-1.2
Bone: cortical porosity1.01.12.00.3-0.3-0.90.8-1.31.31.31.30.10.30.31.3-1.3-1.4-1.4-0.70.80.6-1.4-1.31.1-1.2
Bone: cortical thickness0.20.30.7-0.50.60.8-0.80.6-0.6-0.6-0.60.80.80.7-0.40.40.60.3-0.60.60.60.0-0.00.2-0.3
Bone: cortical thickness0.10.10.30.5-0.5-0.40.4-0.40.40.40.5-0.10.1-0.00.5-0.5-0.4-0.4-0.10.20.4-0.3-0.40.4-0.3
Bone: cortical tissue density1.21.83.5-1.41.41.8-1.81.9-1.9-1.9-1.81.00.90.8-1.51.61.81.5-0.40.2-0.11.11.0-0.60.5
Condit. Reinf. active minus inactive responses0.40.40.91.0-0.9-0.30.30.0-0.0-0.1-0.1-0.9-0.9-0.9-0.30.30.40.51.0-0.9-0.60.70.7-0.80.8
Condit. Reinf. active-inactive response ratio0.70.71.61.2-1.2-0.70.7-0.20.20.20.1-1.3-1.3-1.3-0.10.20.30.41.3-1.2-1.00.70.8-0.81.0
Condit. Reinf. active responses0.10.20.30.5-0.5-0.10.10.2-0.2-0.2-0.2-0.4-0.4-0.5-0.30.30.50.40.5-0.5-0.10.50.5-0.50.5
Condit. Reinf. inactive responses0.10.10.6-0.30.30.3-0.30.1-0.1-0.1-0.10.40.40.30.0-0.00.0-0.1-0.40.30.8-0.1-0.20.2-0.3
Incentive salience index mean0.30.41.01.0-0.9-0.50.5-0.10.10.10.0-0.9-0.9-0.9-0.10.10.30.30.9-0.9-0.60.60.6-0.60.7
Condit. Reinf. lever presses0.10.20.70.9-0.8-0.60.7-0.40.40.40.3-0.6-0.5-0.50.3-0.30.1-0.10.5-0.4-0.10.00.1-0.10.2
Condit. Reinf. active minus inactive responses3.85.915.53.9-3.9-3.13.1-2.52.42.42.2-3.3-3.1-3.11.7-1.7-1.5-1.02.6-2.3-1.30.10.2-0.81.1
Condit. Reinf. active-inactive response ratio0.71.12.11.4-1.5-1.41.4-1.21.21.21.1-1.3-1.2-1.20.9-0.9-0.8-0.61.0-0.9-0.7-0.2-0.1-0.20.3
Condit. Reinf. active responses6.08.623.64.9-4.8-3.73.8-2.92.82.72.5-4.2-3.9-4.01.8-1.8-1.6-0.93.4-3.0-1.60.40.5-1.21.6
Condit. Reinf. inactive responses3.24.714.33.8-3.7-2.62.6-1.91.81.71.6-3.1-3.0-3.01.1-1.1-0.9-0.42.6-2.4-1.20.60.6-1.11.4
Condit. Reinf. lever presses10.315.034.65.9-5.9-5.35.3-4.54.44.44.1-4.9-4.5-4.53.4-3.3-3.2-2.43.5-2.9-1.6-0.8-0.5-0.41.0
Condit. Reinf. lever reinforcers received6.99.726.05.1-5.0-4.14.0-3.13.03.02.8-4.3-4.1-4.12.1-2.0-1.8-1.13.4-3.1-1.80.20.4-1.11.6
Conditioned reinforcement - actives0.41.83.31.3-1.3-1.41.4-1.81.81.81.8-0.5-0.2-0.21.7-1.8-1.8-1.6-0.20.31.0-1.4-1.41.0-1.0
Conditioned reinforcement - inactives0.10.20.7-0.40.50.4-0.40.3-0.3-0.3-0.20.60.50.5-0.30.1-0.00.0-0.50.40.9-0.1-0.20.2-0.3
Conditioned locomotion2.74.17.61.2-1.2-2.32.4-2.52.52.52.6-0.10.20.32.7-2.8-2.4-2.6-0.91.11.5-2.4-2.32.1-1.9
Patch foraging indifference point 0 sec1.13.26.02.3-2.3-2.02.0-2.52.42.42.3-1.9-1.6-1.62.1-2.0-2.3-1.61.0-0.8-0.3-1.0-0.90.2-0.2
Patch foraging indifference point AUC0.40.92.20.9-0.90.1-0.10.4-0.4-0.5-0.5-1.0-1.0-1.1-0.90.80.80.91.2-1.2-1.51.21.2-1.21.3
Delay disc. indifference point, 0s delay0.60.71.61.2-1.3-1.01.0-0.90.90.90.8-1.2-1.1-1.10.7-0.6-0.6-0.40.9-0.9-0.40.00.0-0.30.4
Delay disc. indifference point, 16s delay0.10.11.0-1.00.90.4-0.30.2-0.2-0.2-0.20.40.50.4-0.00.10.10.0-0.40.30.2-0.1-0.10.3-0.2
Delay disc. indifference point, 2s delay0.60.71.70.9-0.9-0.60.6-0.40.30.30.2-1.3-1.3-1.30.00.10.10.31.3-1.2-0.90.60.7-0.80.9
Delay disc. indifference point, 24s delay0.61.03.3-1.81.71.4-1.41.1-1.1-1.1-1.01.11.11.0-0.70.80.80.6-0.80.60.50.30.20.1-0.2
Delay disc. indifference point, 4s delay1.21.23.11.5-1.5-0.40.3-0.30.20.20.1-1.7-1.6-1.8-0.10.20.30.61.7-1.7-1.41.01.1-1.31.4
Delay disc. indifference point, 8s delay0.00.00.3-0.00.00.2-0.00.1-0.1-0.2-0.2-0.00.1-0.0-0.10.20.20.20.1-0.1-0.50.10.10.00.1
Indifference point function ln k0.92.75.10.3-0.3-1.41.4-1.91.91.92.00.30.70.62.2-2.1-2.1-2.2-1.11.21.9-2.1-2.11.9-1.8
Indifference point function log k0.92.75.10.3-0.3-1.41.4-1.91.91.92.00.30.70.62.2-2.1-2.1-2.2-1.11.21.9-2.1-2.11.9-1.8
Patch foraging total patch changes 0 sec0.92.64.82.2-2.2-1.81.8-2.22.12.12.0-1.8-1.6-1.51.8-1.7-2.0-1.41.1-0.9-0.5-0.8-0.70.0-0.0
Patch foraging total patch changes 12 sec1.01.43.31.6-1.6-0.40.3-0.40.30.30.2-1.8-1.7-1.8-0.20.20.00.51.8-1.7-1.71.01.1-1.41.4
Patch foraging total patch changes 18 sec0.81.84.92.2-2.2-1.31.3-1.41.41.41.2-2.0-1.9-1.80.8-0.8-0.9-0.51.6-1.5-1.10.10.2-0.70.7
Patch foraging total patch changes 24 sec0.41.43.21.7-1.7-0.60.7-0.40.40.40.2-1.8-1.8-1.8-0.10.1-0.00.51.7-1.6-1.80.91.0-1.31.3
Patch foraging total patch changes 6 sec0.30.51.01.0-1.0-0.60.6-0.90.90.90.8-0.8-0.6-0.70.8-0.7-0.9-0.50.5-0.4-0.3-0.3-0.2-0.10.0
Patch foraging time to switch 0 sec0.83.06.3-2.52.52.3-2.32.1-2.1-2.0-1.92.32.12.0-1.61.51.51.1-1.61.31.00.40.30.3-0.4
Patch foraging water rate 0 sec0.72.75.11.9-2.0-2.22.1-2.32.22.22.1-1.8-1.5-1.52.0-1.9-1.9-1.51.0-0.7-0.3-0.9-0.80.2-0.2
Patch foraging water rate 12 sec0.62.34.31.6-1.6-1.91.9-2.12.12.12.0-1.0-0.8-0.71.9-2.0-1.8-1.70.20.10.5-1.4-1.30.8-0.8
Patch foraging water rate 18 sec0.61.33.11.8-1.8-1.61.6-1.21.21.21.1-1.5-1.4-1.31.0-0.9-0.9-0.61.1-0.7-0.6-0.1-0.0-0.20.4
Patch foraging water rate 24 sec1.41.93.50.6-0.6-1.21.2-1.71.71.71.80.00.20.31.9-1.8-1.8-1.8-0.71.01.4-1.7-1.71.3-1.4
Patch foraging water rate 6 sec0.91.43.41.0-1.0-1.81.8-1.51.51.51.5-0.5-0.4-0.31.4-1.5-1.5-1.4-0.10.40.1-1.1-1.10.9-0.7
Seeking ratio, delayed vs. immediate footshock0.71.02.4-1.51.51.3-1.30.8-0.8-0.7-0.71.51.31.5-0.50.40.30.1-1.31.30.4-0.4-0.40.7-0.8
Distance traveled before self-admin0.30.61.4-0.60.70.9-0.81.2-1.2-1.2-1.10.70.70.6-1.01.01.10.9-0.30.2-0.30.60.6-0.20.2
Distance traveled after self-admin0.81.54.0-0.60.6-0.20.2-0.10.10.20.31.71.81.70.6-0.6-0.6-0.9-1.81.92.0-1.3-1.41.7-1.7
Extensor digitorum longus weight0.62.34.4-0.30.31.4-1.41.2-1.3-1.3-1.4-0.9-1.1-1.1-1.61.61.71.81.5-1.7-2.11.91.9-2.01.9
Bone: elastic displacement1.31.64.0-1.71.81.3-1.31.1-1.1-1.0-1.02.01.91.9-0.70.70.70.2-1.71.51.3-0.4-0.50.8-1.0
Bone: elastic work1.52.05.1-2.32.21.7-1.71.0-1.0-0.9-0.92.12.02.1-0.60.50.50.0-1.91.70.9-0.7-0.70.9-1.2
Bone: endosteal estimation1.02.56.51.7-1.8-0.90.9-0.80.70.60.5-2.5-2.5-2.50.0-0.1-0.00.52.4-2.4-2.41.21.3-1.71.8
Bone: endosteal perimeter1.12.87.12.1-2.2-1.21.2-1.11.00.90.8-2.7-2.6-2.60.3-0.3-0.20.22.5-2.4-2.21.01.1-1.61.7
Epididymis fat weight0.21.12.5-1.21.11.5-1.51.3-1.3-1.3-1.30.50.40.3-1.61.11.21.20.0-0.3-0.70.90.9-0.60.6
Delta time in closed arm before/after self-admin3.23.05.4-1.11.12.1-2.01.9-2.0-2.0-2.1-0.2-0.5-0.5-2.32.22.22.21.0-1.2-1.72.02.0-1.81.8
Delta time in open arm before/after self-admin1.41.73.71.9-1.9-1.91.7-1.61.51.51.4-1.6-1.6-1.51.1-1.2-1.2-0.91.1-0.9-0.2-0.3-0.2-0.20.3
Diff in mean of infusions in LGA sessions1.62.85.7-1.51.62.0-2.02.4-2.3-2.3-2.22.01.71.7-2.12.02.01.5-1.21.10.70.90.7-0.1-0.0
Delay discount exponential model param0.10.10.30.4-0.4-0.50.4-0.30.30.40.40.10.10.10.3-0.4-0.4-0.4-0.30.30.6-0.4-0.40.3-0.4
Extinction: sum of active levers before priming0.00.10.20.3-0.20.1-0.20.0-0.0-0.0-0.1-0.3-0.4-0.4-0.20.20.20.20.4-0.40.10.30.3-0.30.3
Active lever presses in extinction session 64.74.78.40.4-0.4-2.22.3-2.12.22.22.30.91.31.22.8-2.6-2.5-2.7-1.81.92.2-2.7-2.82.9-2.6
Bone: final force0.10.10.6-0.80.70.5-0.60.4-0.4-0.4-0.40.30.30.2-0.30.30.20.3-0.20.1-0.20.20.1-0.00.0
Bone: final moment0.00.10.4-0.60.50.3-0.40.2-0.2-0.2-0.20.10.10.1-0.20.20.00.2-0.00.0-0.40.20.1-0.10.1
Food consumed during 24 hour testing period1.73.46.71.9-2.0-2.62.6-2.52.52.52.5-1.2-1.0-0.92.3-2.3-2.3-2.10.3-0.00.3-1.6-1.51.1-0.9
Glucose0.00.00.20.00.00.3-0.50.1-0.1-0.1-0.20.0-0.0-0.0-0.20.20.20.10.1-0.2-0.10.10.2-0.30.1
Heart weight0.50.81.61.3-1.2-1.10.9-1.31.31.21.2-0.7-0.6-0.61.0-1.2-1.1-1.00.3-0.30.4-0.7-0.60.3-0.3
Delay discount hyperbolic model param0.20.20.70.2-0.1-0.40.3-0.30.30.40.40.40.30.40.4-0.5-0.5-0.6-0.50.60.8-0.6-0.60.5-0.6
Intermittent access intake day 1-15 change0.10.81.71.0-0.9-1.01.0-1.01.01.11.1-0.2-0.1-0.11.3-1.2-1.0-1.0-0.20.40.9-0.9-0.80.6-0.6
Intermittent access intake escalation0.21.02.01.2-1.1-1.21.1-1.21.21.31.2-0.3-0.2-0.11.4-1.3-1.2-1.2-0.20.40.9-1.0-0.90.7-0.7
Intermittent access intake escalation 20.20.41.00.9-0.9-0.60.6-0.90.90.90.8-0.7-0.5-0.51.0-0.8-0.7-0.60.3-0.10.1-0.4-0.3-0.0-0.1
Intermitt. access day 1 inactive lever presses0.11.22.2-1.41.41.5-1.41.4-1.4-1.4-1.40.70.50.5-1.31.21.21.2-0.2-0.1-0.10.90.8-0.60.5
Intermitt. access day 15 inactive lever presses0.10.72.2-0.70.80.0-0.10.4-0.4-0.3-0.21.41.41.3-0.10.10.0-0.3-1.31.11.5-0.6-0.71.1-1.0
Intermitt. access escalation Index0.00.00.6-0.10.0-0.10.1-0.10.10.10.1-0.2-0.2-0.20.2-0.1-0.1-0.00.2-0.1-0.70.00.1-0.00.1
Intermittent access day 1 total infusions0.61.84.21.8-1.8-2.02.0-1.71.71.71.7-0.8-0.7-0.61.2-1.5-1.6-1.40.2-0.10.6-1.1-1.00.9-0.7
Intermittent access day 15 total infusions0.92.24.02.0-1.8-2.01.9-1.91.91.91.9-0.6-0.4-0.41.7-1.8-1.8-1.7-0.10.31.1-1.4-1.31.1-1.0
Intermittent access terminal intake (last 3 days)1.32.34.52.1-2.0-2.02.0-1.91.91.91.9-0.9-0.7-0.72.0-1.9-1.7-1.60.3-0.00.7-1.2-1.10.8-0.7
Intermittent access total infusions1.61.94.32.1-2.0-2.02.0-1.71.71.71.7-1.2-1.1-1.01.3-1.5-1.5-1.30.6-0.40.5-0.8-0.80.5-0.3
Intermittent access day 1 locomotion0.40.71.40.7-0.6-1.21.2-0.90.90.91.00.20.20.30.7-1.0-0.9-1.0-0.50.41.0-1.0-1.01.1-0.9
Intermittent access day 15 total locomotion0.52.03.40.7-0.7-1.71.7-1.71.71.71.70.10.20.31.6-1.8-1.6-1.8-0.70.81.3-1.7-1.71.6-1.4
Intermittent access total locomotion1.11.33.21.2-1.1-1.81.7-1.41.41.41.4-0.3-0.2-0.11.1-1.4-1.2-1.3-0.20.31.2-1.1-1.11.1-0.9
Intermittent access standard deviation0.10.31.00.5-0.40.0-0.10.1-0.1-0.2-0.2-0.7-0.7-0.8-0.20.20.40.50.9-1.0-0.40.70.7-0.80.8
Left kidney weight0.32.24.90.9-0.90.5-0.60.4-0.5-0.5-0.7-1.8-1.9-2.0-1.11.01.01.42.1-2.2-2.21.81.9-2.22.1
Right kidney weight0.53.58.21.1-1.20.3-0.30.4-0.5-0.6-0.8-2.4-2.5-2.5-1.21.11.11.72.7-2.8-2.92.22.3-2.62.7
Cocaine induced anxiety0.61.64.9-2.22.21.7-1.61.4-1.4-1.4-1.31.51.51.4-1.01.11.10.8-1.10.80.40.30.20.2-0.3
Post-drug Anxiety1.41.62.8-1.71.71.6-1.61.7-1.7-1.7-1.61.31.21.1-1.41.41.41.1-0.70.50.40.70.6-0.20.1
Baseline Anxiety0.20.31.41.2-1.1-0.70.6-0.30.30.30.3-0.7-0.8-0.80.0-0.1-0.10.00.7-0.50.00.30.3-0.40.4
Tail length1.05.412.22.5-2.4-0.50.30.3-0.4-0.4-0.6-3.1-3.3-3.4-1.31.31.41.93.5-3.4-2.52.72.8-3.13.2
Length with tail0.93.88.32.4-2.3-0.80.50.3-0.4-0.4-0.5-2.5-2.7-2.8-1.31.11.31.62.9-2.8-1.72.32.3-2.52.6
Length without tail0.00.20.70.3-0.2-0.10.10.6-0.6-0.6-0.60.1-0.0-0.1-0.90.60.70.60.2-0.30.20.60.5-0.20.4
Times rat made contact with spout0.70.81.5-0.40.40.7-0.71.0-1.0-1.0-1.0-0.3-0.4-0.5-1.11.21.21.20.8-0.7-1.01.21.2-1.11.1
Lifetime Intake1.92.35.12.2-2.2-2.32.2-2.01.92.01.9-1.3-1.2-1.01.4-1.7-1.7-1.50.6-0.30.6-1.0-0.90.6-0.4
Liver weight, left0.91.63.0-0.0-0.01.0-0.90.9-1.0-1.0-1.1-1.0-1.1-1.1-1.21.31.21.51.4-1.5-1.61.61.7-1.71.7
Liver weight, right2.23.86.3-0.40.42.0-2.02.0-2.0-2.1-2.1-0.7-1.0-1.1-2.32.32.22.51.6-1.8-1.92.52.5-2.52.3
Locomotor activity0.30.51.10.7-0.8-0.70.7-0.90.90.90.9-0.4-0.2-0.41.0-0.9-1.0-0.80.1-0.10.0-0.6-0.60.4-0.3
Locomotor testing distance0.61.43.31.8-1.8-1.31.2-1.31.21.21.1-1.7-1.5-1.61.0-0.8-0.8-0.51.3-1.2-1.00.10.1-0.50.6
Locomotor testing rearing0.31.12.51.5-1.4-0.40.3-0.20.10.10.0-1.5-1.4-1.6-0.20.30.40.61.6-1.6-1.21.01.0-1.21.3
Locomotion in novel chamber0.81.13.5-0.30.2-0.70.8-1.11.21.11.20.30.60.51.9-1.2-1.3-1.3-0.80.80.8-1.4-1.41.3-1.2
Locomotion in novel chamber post-restriction0.72.24.11.5-1.5-2.02.0-2.02.02.02.0-0.8-0.7-0.51.8-1.8-1.8-1.70.10.10.1-1.4-1.30.9-0.8
Fecal boli incidents, locomotor time 10.41.12.40.1-0.2-0.81.1-1.21.21.21.20.10.30.41.5-1.5-1.4-1.3-0.70.80.6-1.3-1.31.3-1.1
Change in fecal boli incidents, locomotor task0.40.51.0-0.60.60.7-0.81.0-0.9-0.9-0.90.40.20.2-1.01.00.90.8-0.0-0.0-0.40.70.6-0.50.4
Time >=10cm from walls, locomotor time 11.31.63.31.0-1.0-1.51.6-1.71.71.71.7-0.6-0.4-0.31.8-1.8-1.7-1.5-0.10.30.3-1.3-1.31.0-0.9
Bouts of movement, locomotor time 10.20.20.91.0-0.8-0.30.4-0.50.50.50.5-0.2-0.1-0.20.6-0.6-0.5-0.40.0-0.00.5-0.3-0.30.3-0.2
Total resting periods, locomotor time 10.40.50.90.6-0.5-0.50.6-0.60.60.60.70.30.50.40.8-0.9-0.8-0.8-0.60.60.9-0.8-0.90.9-0.8
Rest time, locomotor task time 10.40.71.90.1-0.0-0.40.6-0.30.40.40.50.90.91.00.5-0.6-0.7-0.8-1.11.01.4-1.0-1.01.2-1.1
Distance moved, locomotor task time 10.31.02.8-0.10.00.8-0.90.4-0.5-0.5-0.6-1.0-1.0-1.1-0.70.80.81.01.3-1.3-1.71.21.3-1.51.4
Vertical activity count, locomotor time 10.10.51.50.4-0.4-0.1-0.0-0.0-0.0-0.0-0.1-1.1-1.1-1.1-0.30.40.20.51.1-1.1-1.20.80.8-1.01.0
Time >=10cm from walls, locomotor time 20.41.12.91.7-1.7-1.21.1-1.21.21.11.1-1.4-1.3-1.30.8-0.8-0.9-0.51.0-0.8-0.0-0.1-0.1-0.30.3
Bouts of movement, locomotor time 20.30.92.10.7-0.70.6-0.70.1-0.2-0.2-0.3-1.3-1.3-1.4-0.30.40.60.81.4-1.5-1.21.21.1-1.41.4
Total resting periods, locomotor time 20.20.81.80.3-0.30.9-1.00.4-0.4-0.5-0.5-0.9-0.9-1.1-0.50.60.70.91.1-1.2-1.01.11.1-1.31.2
Rest time, locomotor task time 21.11.83.1-1.71.71.6-1.61.7-1.7-1.6-1.61.81.51.6-1.61.41.20.9-1.21.01.00.40.30.2-0.3
Distance moved, locomotor task time 21.41.84.52.1-2.1-1.11.0-1.51.51.51.4-2.0-1.8-1.91.2-1.0-1.1-0.61.5-1.4-0.8-0.00.1-0.70.6
Vertical activity count, locomotor time 20.30.72.21.0-1.0-0.50.5-0.70.70.60.6-1.5-1.4-1.40.3-0.2-0.40.01.3-1.3-0.70.40.5-0.90.8
Light reinforcement 10.73.08.0-2.42.42.8-2.82.1-2.1-2.1-2.11.61.31.4-1.91.81.71.5-0.90.6-0.10.90.8-0.60.2
Light reinforcement 20.20.41.0-1.01.00.5-0.60.2-0.2-0.1-0.10.90.81.0-0.0-0.1-0.2-0.3-0.91.00.1-0.6-0.50.5-0.7
Bone: marrow area1.02.35.91.5-1.6-0.70.7-0.60.50.50.3-2.4-2.4-2.4-0.10.10.10.62.4-2.4-2.41.21.3-1.71.8
Bone: maximum diameter0.91.94.82.2-2.2-1.00.8-1.01.01.00.8-2.1-2.1-2.10.5-0.5-0.3-0.01.9-1.8-1.30.60.7-1.21.2
Bone: maximum force0.00.00.2-0.50.40.3-0.40.2-0.2-0.2-0.20.20.20.2-0.10.1-0.00.1-0.10.1-0.30.10.00.0-0.0
Bone: maximum moment0.00.00.2-0.30.20.1-0.20.0-0.0-0.0-0.0-0.0-0.0-0.1-0.00.0-0.10.00.0-0.0-0.50.10.0-0.10.1
Mean time between licks in bursts0.74.411.23.1-3.1-1.21.0-1.11.00.90.8-3.3-3.2-3.40.2-0.2-0.10.53.1-2.9-2.41.51.5-2.22.3
Mean num. licks in bursts1.23.36.32.1-2.1-2.52.4-2.52.52.52.4-1.5-1.2-1.12.2-2.3-2.1-1.90.6-0.20.1-1.4-1.30.8-0.7
Cd content in liver0.70.71.2-0.40.40.8-0.90.9-0.9-0.9-1.0-0.2-0.4-0.4-1.11.11.11.10.6-0.7-0.71.11.1-1.00.9
Co content in liver0.91.12.71.5-1.5-1.01.0-0.70.70.60.6-1.6-1.6-1.60.3-0.3-0.30.11.5-1.4-0.80.60.6-0.81.0
Cu content in liver1.41.63.91.3-1.3-0.10.00.2-0.3-0.3-0.4-1.7-1.8-1.8-0.80.80.61.11.9-2.0-1.41.51.5-1.81.8
Fe content in liver0.00.00.0-0.20.10.0-0.00.2-0.2-0.1-0.10.10.10.1-0.20.2-0.20.1-0.10.10.10.00.00.0-0.0
K content in liver0.40.40.7-0.10.10.4-0.50.6-0.6-0.7-0.7-0.3-0.3-0.4-0.80.80.80.80.5-0.7-0.00.80.8-0.80.7
Mg content in liver0.00.00.10.1-0.2-0.20.2-0.30.20.20.2-0.4-0.3-0.30.1-0.1-0.1-0.10.3-0.30.20.00.0-0.20.1
Mn content in liver1.11.23.0-1.61.60.7-0.70.4-0.4-0.4-0.31.71.71.70.0-0.0-0.1-0.4-1.61.61.2-0.9-0.91.2-1.3
Na content in liver0.40.51.11.0-0.9-1.10.9-0.90.80.90.8-0.6-0.5-0.50.6-0.6-0.9-0.60.3-0.20.5-0.4-0.30.2-0.2
Rb content in liver0.20.20.50.6-0.6-0.70.6-0.60.60.60.6-0.6-0.5-0.50.4-0.4-0.4-0.40.4-0.3-0.2-0.2-0.1-0.00.1
Se content in liver2.73.27.3-2.72.72.2-2.21.9-1.9-1.8-1.72.62.42.4-1.41.41.10.8-2.01.71.6-0.0-0.10.6-0.9
Sr content in liver0.40.30.60.2-0.2-0.40.4-0.60.60.60.60.20.30.30.6-0.6-0.8-0.8-0.50.60.6-0.8-0.70.7-0.7
Zn content in liver1.61.94.42.0-2.0-1.41.4-1.41.31.31.2-2.1-2.0-2.00.8-0.8-0.8-0.41.7-1.6-0.90.20.3-0.80.9
Bone: minimum diameter1.42.65.91.3-1.30.2-0.40.4-0.5-0.5-0.6-2.0-2.1-2.2-1.01.01.21.52.4-2.4-2.02.02.0-2.32.3
Time in familiar zone, hab. session 10.20.20.40.2-0.20.1-0.10.3-0.3-0.3-0.3-0.4-0.5-0.5-0.50.40.50.50.6-0.6-0.60.60.6-0.60.6
Time in novel zone, hab. session 10.10.20.4-0.30.40.6-0.50.6-0.5-0.5-0.50.40.40.4-0.40.40.30.4-0.30.20.50.20.2-0.10.0
Total zone transitions, hab. session 10.50.62.10.5-0.4-0.50.5-0.50.50.60.60.70.70.70.7-0.7-0.7-0.9-0.91.01.5-1.0-1.01.1-1.1
Total locomotion distance, hab. session 11.52.23.9-0.10.11.2-1.21.6-1.6-1.7-1.7-0.5-0.6-0.8-1.81.81.82.01.1-1.3-1.32.01.9-1.81.7
Locomotion velocity, hab. session 10.91.32.40.00.00.9-0.91.2-1.2-1.3-1.3-0.4-0.5-0.7-1.31.41.41.50.9-1.1-1.01.61.5-1.41.4
Time in familiar zone, hab. session 20.91.02.61.2-1.3-1.51.6-1.11.11.11.0-1.4-1.4-1.30.8-0.7-0.6-0.41.1-1.0-0.9-0.00.0-0.10.5
Time in novel zone, hab. session 20.30.40.9-0.60.70.7-0.80.4-0.4-0.4-0.31.01.01.0-0.10.10.0-0.1-0.90.80.9-0.3-0.30.3-0.6
Total zone transitions, hab. session 21.52.03.11.7-1.6-1.81.6-1.71.71.71.8-0.3-0.1-0.11.7-1.7-1.8-1.7-0.30.61.4-1.4-1.41.1-1.1
Total locomotion distance, hab. session 21.01.32.61.1-1.00.2-0.30.7-0.7-0.8-0.8-1.1-1.2-1.4-1.11.00.91.31.5-1.6-0.81.61.6-1.61.6
Locomotion velocity, hab. session 21.31.73.51.0-0.90.3-0.40.9-1.0-1.0-1.0-1.1-1.3-1.4-1.31.31.21.61.6-1.8-1.01.91.8-1.81.8
Novel to familiar place preference ratio0.10.10.80.4-0.4-0.20.1-0.20.20.20.3-0.10.0-0.10.3-0.3-0.4-0.2-0.00.10.9-0.1-0.20.0-0.1
Novelty place preference0.10.10.90.5-0.4-0.20.0-0.20.20.20.3-0.10.0-0.10.3-0.3-0.3-0.2-0.00.11.0-0.1-0.20.0-0.1
Time in novel zone, NPP test0.10.21.00.7-0.6-0.50.3-0.40.40.40.5-0.2-0.0-0.20.5-0.5-0.6-0.30.00.11.0-0.2-0.30.1-0.2
Total zone transitions, NPP test0.40.61.10.8-0.7-0.80.8-0.80.80.80.80.30.40.40.9-0.9-0.9-1.0-0.60.61.0-1.0-0.90.9-0.9
Total locomotion distance, NPP test1.01.42.70.1-0.01.0-1.01.2-1.3-1.3-1.3-0.5-0.6-0.7-1.41.41.41.61.0-1.2-1.01.61.6-1.51.5
Locomotion velocity, NPP test1.21.83.1-0.20.31.4-1.31.5-1.5-1.6-1.6-0.2-0.4-0.5-1.71.71.61.80.9-1.1-1.01.71.7-1.51.5
Intraocular pressure0.30.61.3-0.40.3-0.10.1-0.70.70.80.70.40.50.71.0-0.9-1.0-1.0-0.80.80.3-1.2-1.00.8-1.0
Delta distance traveled before/after self-admin2.22.44.11.3-1.2-1.71.6-1.81.91.91.9-0.10.10.11.9-2.0-2.0-1.9-0.60.81.8-1.7-1.71.4-1.4
Delta ambulatory time before/after self-admin1.42.54.41.0-1.0-1.71.6-1.91.91.91.9-0.00.20.32.0-2.1-2.1-2.0-0.70.91.8-1.8-1.81.6-1.5
Parametrial fat weight0.51.33.2-1.01.01.8-1.81.4-1.4-1.4-1.40.60.30.5-1.71.31.31.2-0.0-0.2-0.80.90.9-0.90.6
Pavlov. Cond. lever latency0.91.12.6-1.61.61.5-1.51.3-1.2-1.2-1.21.31.21.2-1.01.00.80.7-0.90.80.60.30.20.0-0.2
Pavlov. Cond. magazine entry latency2.22.87.02.1-2.2-2.52.6-1.91.91.91.8-2.1-2.0-1.91.4-1.4-1.3-1.01.5-1.3-1.2-0.3-0.2-0.00.4
Pavlov. Cond. change in total contacts1.01.12.71.5-1.5-1.61.6-1.21.21.21.1-1.3-1.2-1.20.8-0.8-0.9-0.60.9-0.8-0.6-0.2-0.10.00.2
Pavlov. Cond. index score1.82.35.02.1-2.1-2.22.2-1.81.71.71.6-2.0-1.8-1.81.3-1.3-1.1-0.91.4-1.2-1.2-0.3-0.1-0.10.5
Pavlov. Cond. latency score1.72.24.92.1-2.1-2.12.2-1.71.71.71.6-1.9-1.7-1.71.3-1.3-1.1-0.91.3-1.2-1.1-0.3-0.2-0.00.4
Pavlov. Cond. lever contacts0.81.02.21.5-1.5-1.31.3-1.11.11.11.0-1.4-1.3-1.20.8-0.8-0.6-0.51.0-0.9-0.9-0.10.0-0.20.4
Pavlov. Cond. magazine entry number2.22.86.7-2.22.32.5-2.62.0-1.9-1.9-1.82.12.01.9-1.51.51.41.1-1.51.21.10.40.30.0-0.4
Pavlov. Cond. intertrial magazine entries0.60.71.5-1.01.01.1-1.20.9-0.9-0.9-0.81.21.11.1-0.60.70.40.4-0.90.80.70.1-0.00.2-0.4
Pavlov. Cond. lever-magazine prob. diff.1.51.94.31.9-1.9-2.02.1-1.61.61.51.4-1.7-1.6-1.61.1-1.2-1.1-0.81.3-1.1-1.1-0.3-0.2-0.00.4
Pavlov. Cond. response bias1.11.33.31.6-1.6-1.71.8-1.31.31.31.2-1.5-1.4-1.30.9-0.9-0.8-0.71.1-0.9-0.8-0.2-0.1-0.00.3
Pavlov. Cond. lever latency11.215.735.9-6.06.05.4-5.34.9-4.8-4.7-4.54.74.34.2-3.83.73.62.8-3.22.51.21.21.00.1-0.5
Pavlov. Cond. magazine entry latency2.53.57.72.0-2.1-2.82.8-2.52.52.52.4-1.6-1.4-1.32.2-2.2-2.1-1.90.8-0.4-0.1-1.3-1.20.8-0.5
Pavlov. Cond. change in total contacts5.012.228.25.3-5.3-4.94.7-4.34.34.24.1-4.0-3.6-3.53.4-3.4-3.2-2.62.6-2.0-0.5-1.3-1.00.20.2
Pavlov. Cond. index score7.311.423.64.8-4.9-4.74.5-4.34.24.14.0-3.9-3.6-3.53.3-3.3-3.2-2.62.5-2.0-0.8-1.2-1.00.10.3
Pavlov. Cond. latency score6.210.020.54.5-4.5-4.34.2-4.04.03.93.8-3.6-3.3-3.23.2-3.2-3.1-2.52.3-1.7-0.6-1.3-1.00.20.2
Pavlov. Cond. lever contacts10.014.834.25.8-5.8-5.15.0-4.74.64.64.4-4.6-4.2-4.23.6-3.6-3.4-2.73.1-2.5-1.1-1.1-0.9-0.20.6
Pavlov. Cond. magazine entry number4.86.213.6-3.03.13.7-3.63.3-3.3-3.3-3.22.22.01.8-2.82.82.72.4-1.10.6-0.11.61.4-0.90.6
Pavlov. Cond. intertrial magazine entries0.61.43.10.8-0.70.6-0.70.6-0.6-0.7-0.7-1.2-1.3-1.4-1.01.01.01.21.5-1.7-1.31.51.5-1.81.6
Pavlov. Cond. lever-magazine prob. diff.6.810.521.94.7-4.7-4.54.4-4.04.03.93.7-3.9-3.6-3.53.1-3.1-3.0-2.32.6-2.0-0.9-1.0-0.8-0.00.4
Pavlov. Cond. response bias11.115.332.15.7-5.7-5.55.4-4.94.84.84.6-4.5-4.1-4.03.8-3.8-3.6-3.02.9-2.3-1.1-1.4-1.20.20.3
Time in closed arm before self-admin1.93.35.51.4-1.3-2.42.3-2.02.12.12.20.10.40.32.3-2.2-2.2-2.2-0.91.11.6-2.0-2.01.9-1.8
Time in closed arm after self-admin0.60.71.8-1.11.10.5-0.40.5-0.5-0.5-0.41.31.41.3-0.20.10.2-0.1-1.21.10.7-0.5-0.60.9-0.9
Time in open arm before self-admin2.83.48.9-2.72.63.0-2.92.2-2.2-2.2-2.21.31.21.1-1.82.12.01.7-0.60.3-0.51.11.1-0.90.6
Time in open arm after self-admin0.50.61.50.2-0.30.4-0.50.2-0.3-0.3-0.4-0.9-1.0-1.0-0.50.60.60.71.1-1.1-0.70.91.0-1.21.1
Bone: periosteal estimation0.81.84.61.5-1.6-0.60.5-0.60.50.50.3-2.1-2.1-2.2-0.00.00.10.52.1-2.1-2.01.01.1-1.51.6
Bone: periosteal perimeter0.81.64.11.7-1.7-0.70.6-0.70.60.60.5-2.0-2.0-2.00.1-0.10.00.31.9-1.9-1.60.91.0-1.41.4
Bone: post-yield work0.00.00.10.3-0.3-0.20.2-0.10.10.10.1-0.3-0.3-0.30.0-0.0-0.10.10.3-0.3-0.20.10.1-0.10.2
Progressive ratio test 1 active lever presses0.30.41.50.3-0.2-0.80.9-0.40.40.50.50.50.50.60.2-0.6-0.6-0.7-0.70.71.2-0.8-0.81.0-0.8
Progressive ratio test 1 breakpoint0.20.41.40.3-0.2-0.80.8-0.40.40.40.40.50.40.60.2-0.5-0.5-0.7-0.70.61.2-0.7-0.70.9-0.8
Progressive ratio test 1 inactive lever presses0.10.31.80.10.0-0.40.4-0.30.30.30.30.50.40.6-0.1-0.4-0.5-0.5-0.70.61.4-0.7-0.70.7-0.7
Progressive ratio test 2 active lever presses0.30.41.61.3-1.2-0.90.8-0.80.70.70.7-0.7-0.7-0.60.4-0.4-0.5-0.40.5-0.30.3-0.2-0.1-0.10.1
Progressive ratio test 2 breakpoint0.30.41.61.3-1.2-0.90.8-0.80.80.80.7-0.7-0.7-0.60.4-0.5-0.5-0.50.5-0.30.4-0.3-0.2-0.10.0
Progressive ratio test 2 inactive lever presses0.20.72.10.7-0.6-1.01.0-0.90.91.01.00.00.10.20.6-1.0-0.9-1.0-0.40.51.5-1.0-0.90.9-0.8
Incentive Sensitization - Responses0.20.61.61.3-1.3-0.70.6-0.80.80.80.7-1.2-1.1-1.10.6-0.4-0.4-0.30.9-0.6-0.20.00.1-0.50.4
Incentive Sensitization - Breakpoint0.20.51.41.2-1.2-0.70.6-0.90.80.80.8-1.0-0.9-0.90.6-0.5-0.5-0.40.8-0.5-0.1-0.1-0.0-0.40.3
Sum of active levers in priming session hrs 5-60.30.31.10.2-0.2-0.50.4-0.10.20.20.30.60.70.50.4-0.3-0.3-0.4-0.60.61.1-0.5-0.60.8-0.7
Progressive ratio0.20.61.60.2-0.2-1.21.3-0.90.91.01.0-0.1-0.00.11.0-1.0-0.9-1.0-0.30.5-0.1-0.9-0.80.9-0.7
Food seeking constrained by brief footshock0.91.23.01.7-1.7-0.90.9-0.70.60.60.5-1.7-1.6-1.70.3-0.3-0.20.21.6-1.5-1.00.60.7-1.01.1
Seeking ratio, punishment vs. effort0.71.64.11.4-1.30.3-0.50.3-0.3-0.4-0.4-1.6-1.7-1.8-0.80.80.71.11.9-2.0-1.11.51.6-1.91.8
Retroperitoneal fat weight2.712.122.3-1.71.73.6-3.54.0-4.1-4.1-4.2-0.3-0.8-0.9-4.74.44.34.51.9-2.5-3.74.24.2-3.73.6
Reaction time number correct0.41.54.5-0.20.2-0.50.4-0.80.90.91.01.01.21.11.4-1.2-1.0-1.4-1.41.52.1-1.5-1.61.5-1.6
Reaction time mean minus median0.10.61.61.3-1.2-0.90.9-0.70.60.60.6-1.2-1.1-1.20.3-0.5-0.3-0.11.0-0.8-0.60.30.3-0.50.6
Reaction time mean minus median AUC0.10.81.71.3-1.2-1.31.3-1.21.21.21.2-0.9-0.8-0.81.0-1.1-0.9-0.80.5-0.20.2-0.5-0.50.2-0.1
Reaction time num false alarms1.32.24.2-1.51.52.0-1.92.0-2.0-2.1-2.00.80.60.5-1.82.01.81.8-0.0-0.2-0.41.51.3-1.00.9
Reaction time num false alarms AUC0.51.12.1-1.21.21.5-1.41.4-1.4-1.4-1.40.60.60.5-1.21.31.11.2-0.2-0.1-0.10.90.8-0.50.5
Reaction time trials correct on left0.41.54.5-0.20.2-0.50.4-0.80.90.91.01.01.21.11.4-1.2-1.0-1.4-1.41.52.1-1.5-1.61.5-1.6
Reaction time trials on left0.41.54.5-0.20.2-0.50.4-0.80.90.91.01.01.21.11.4-1.2-1.0-1.4-1.41.52.1-1.5-1.61.5-1.6
Reaction time mean0.41.01.9-0.80.81.0-1.01.4-1.4-1.4-1.40.30.10.0-1.31.31.21.30.2-0.2-0.41.21.1-0.80.8
Reaction time mean AUC0.41.02.0-1.01.01.1-1.01.4-1.4-1.4-1.40.60.40.4-1.31.21.11.2-0.10.20.11.00.9-0.50.5
Median of all reaction times0.91.42.8-1.41.41.4-1.31.7-1.7-1.7-1.60.80.60.5-1.51.51.31.4-0.20.2-0.11.11.0-0.60.6
Reaction time omissions0.20.40.7-0.00.00.3-0.20.6-0.6-0.7-0.7-0.3-0.4-0.4-0.70.70.60.80.6-0.7-0.50.90.8-0.70.8
Reaction time false alarm rate1.42.03.6-1.21.21.6-1.51.8-1.8-1.8-1.80.20.1-0.0-1.81.91.61.80.4-0.7-1.21.61.5-1.21.2
Reaction time premature initiation rate1.93.011.21.7-1.8-0.50.6-0.20.20.1-0.1-2.5-2.6-2.5-0.50.40.51.02.5-2.5-3.41.61.7-2.02.2
Reaction time premature initiations0.41.23.51.4-1.5-0.80.8-0.80.70.70.6-1.7-1.6-1.60.5-0.4-0.30.01.5-1.4-1.90.50.5-0.91.0
Std. dev. reaction times0.41.22.50.9-0.80.1-0.00.4-0.4-0.5-0.5-1.3-1.4-1.5-0.80.80.81.11.6-1.5-1.41.41.4-1.51.6
Reaction time trials completed0.41.54.5-0.20.2-0.50.4-0.80.90.91.01.01.21.11.4-1.2-1.0-1.4-1.41.52.1-1.5-1.61.5-1.6
Reaction time trials AUC0.31.03.3-0.10.1-0.40.3-0.70.70.70.90.81.00.91.3-1.0-0.9-1.2-1.21.31.8-1.3-1.31.2-1.4
Run reversals in cocaine runway, females3.13.56.40.5-0.50.9-0.91.5-1.6-1.6-1.7-1.3-1.6-1.6-2.21.82.12.32.0-2.1-2.52.52.5-2.52.5
Run reversals in cocaine runway, males0.10.10.9-0.90.8-0.30.40.1-0.1-0.0-0.10.40.30.4-0.2-0.10.0-0.1-0.40.3-0.2-0.3-0.20.5-0.3
Latency to leave start box in cocaine runway2.63.67.3-1.41.42.4-2.32.5-2.5-2.5-2.50.70.30.4-2.72.62.52.30.2-0.4-1.21.91.9-1.51.4
Latency to leave start box in cocaine runway, F3.74.69.1-1.01.12.6-2.52.6-2.6-2.6-2.70.2-0.3-0.2-3.02.92.82.70.9-1.1-1.82.42.4-2.12.0
Latency to leave start box in cocaine runway, M0.20.20.6-0.70.70.4-0.30.4-0.4-0.3-0.30.70.60.8-0.30.20.20.0-0.60.70.0-0.2-0.20.4-0.4
Std. dev. time between licks in bursts1.42.66.21.6-1.6-0.20.10.0-0.1-0.2-0.3-2.3-2.3-2.4-0.60.70.71.22.4-2.4-2.51.81.8-2.22.2
Total sessions with >9 infusions1.92.35.22.2-2.2-2.32.3-1.91.91.91.8-1.6-1.6-1.41.1-1.5-1.5-1.21.0-0.80.1-0.7-0.60.2-0.0
Short access day 1 total inactive lever presses0.10.10.50.7-0.6-0.40.4-0.20.20.30.2-0.2-0.4-0.2-0.4-0.3-0.3-0.20.1-0.00.6-0.1-0.1-0.0-0.0
Short access day 10 total inactive lever presses0.10.51.2-1.11.10.8-0.70.8-0.8-0.8-0.70.90.90.8-0.50.50.50.4-0.70.60.30.10.00.2-0.2
Short access day 1 total infusions1.53.08.42.9-2.8-2.32.2-2.02.02.01.8-2.3-2.2-2.11.1-1.3-1.5-1.01.6-1.3-0.4-0.3-0.2-0.30.5
Short access day 10 total infusions1.11.95.02.2-2.2-2.12.1-1.61.61.61.5-1.5-1.4-1.31.0-1.1-1.2-1.01.0-0.80.1-0.5-0.40.20.1
Short access total infusions1.82.65.82.4-2.3-2.42.3-2.12.02.12.0-1.5-1.5-1.21.3-1.6-1.8-1.50.8-0.60.4-0.9-0.80.4-0.3
Short access day 1 locomotion1.52.54.81.3-1.3-2.02.1-2.22.22.22.1-0.8-0.7-0.41.7-2.0-2.0-1.9-0.00.20.8-1.6-1.51.2-1.0
Short access day 10 total locomotion0.31.12.71.4-1.4-1.61.6-1.31.31.31.2-1.1-0.9-1.01.2-1.2-0.9-0.80.7-0.60.0-0.4-0.40.20.0
Short access total locomotion0.60.91.90.6-0.6-1.41.4-1.21.21.21.2-0.2-0.1-0.01.1-1.3-1.0-1.2-0.20.20.9-1.1-1.01.0-0.8
One hour access (0.3 mA shock)1.11.32.71.5-1.5-1.61.6-1.51.41.51.4-0.9-0.8-0.71.3-1.5-1.2-1.10.4-0.20.5-0.8-0.70.5-0.3
Compulsive drug intake1.31.94.2-1.91.90.6-0.60.2-0.1-0.10.11.92.12.00.7-0.4-0.6-0.8-2.02.01.7-1.4-1.41.5-1.7
One hour access (shock baseline)0.82.25.52.3-2.3-2.12.1-1.81.81.81.7-1.5-1.4-1.31.4-1.6-1.3-1.20.9-0.7-0.0-0.6-0.50.2-0.0
Social response proportion0.60.81.8-0.50.51.3-1.31.0-1.0-1.0-1.0-0.1-0.3-0.3-1.11.01.01.10.5-0.6-0.71.11.0-1.10.9
Social responses1.21.63.00.00.01.1-1.11.2-1.2-1.3-1.3-0.7-0.8-0.9-1.61.41.31.71.2-1.3-0.81.71.7-1.71.6
Social time1.32.04.1-1.71.81.8-1.91.5-1.5-1.4-1.32.01.91.8-1.00.91.10.6-1.61.32.00.0-0.10.5-0.7
Soleus weight1.64.79.70.0-0.01.8-1.81.7-1.8-1.8-2.0-1.4-1.7-1.7-2.22.22.32.62.2-2.6-3.12.82.8-2.92.8
Bone: stiffness0.40.81.4-0.90.81.0-1.11.2-1.2-1.2-1.20.30.20.1-1.11.11.11.10.2-0.3-0.61.00.9-0.70.7
Tibialis anterior weight0.20.81.80.3-0.40.4-0.40.4-0.4-0.4-0.5-1.0-1.1-1.1-0.70.70.70.91.2-1.4-1.31.21.2-1.31.3
Time to tail flick, vehicle, before self-admin0.20.30.60.7-0.7-0.70.5-0.60.60.60.6-0.1-0.1-0.10.7-0.6-0.6-0.6-0.00.10.5-0.4-0.40.3-0.3
Time to tail flick, vehicle, after self-admin0.61.32.41.5-1.4-1.41.3-1.51.51.51.5-0.9-0.9-0.71.1-1.4-1.4-1.20.4-0.30.8-0.8-0.80.3-0.4
Time to tail flick, test, before self-admin0.80.92.31.5-1.5-0.70.6-0.30.20.20.1-1.3-1.4-1.3-0.20.20.20.41.3-1.3-1.40.80.8-0.91.0
Time to tail flick, test, after self-admin0.90.92.01.1-1.0-0.30.20.1-0.2-0.2-0.3-1.3-1.4-1.4-0.60.50.50.81.4-1.4-1.01.21.1-1.31.3
Delta time to tail flick, vehicle, before/after SA0.40.40.80.5-0.6-0.80.9-0.90.90.90.8-0.7-0.7-0.50.5-0.8-0.8-0.60.3-0.3-0.2-0.4-0.40.1-0.1
Delta time to tail flick, test, before/after SA0.30.30.7-0.80.80.8-0.80.7-0.7-0.7-0.60.60.50.5-0.50.50.40.4-0.40.40.60.20.1-0.1-0.0
Tibia length1.54.38.91.5-1.5-3.02.9-2.72.72.72.7-0.6-0.3-0.32.7-2.7-2.4-2.5-0.40.81.0-2.1-2.11.9-1.6
Ambulatory time before self-admin0.20.61.4-0.80.90.7-0.71.0-1.0-1.0-0.91.11.21.0-0.60.70.80.5-0.80.70.30.20.10.3-0.3
Ambulatory time after self-admin1.62.56.5-0.10.2-1.00.9-0.80.90.91.11.61.81.71.4-1.5-1.4-1.7-2.02.02.6-2.0-2.02.3-2.2
Bone: tissue strength1.41.53.6-1.21.20.1-0.2-0.10.20.20.31.61.71.80.6-0.6-0.7-1.0-1.81.91.6-1.4-1.41.6-1.7
Total heroin consumption0.20.20.60.5-0.5-0.60.6-0.30.30.30.40.30.30.20.3-0.4-0.4-0.4-0.40.40.7-0.4-0.50.6-0.5
Bone: trabecular number0.61.02.8-1.31.41.0-0.90.8-0.8-0.7-0.71.71.61.6-0.30.40.50.0-1.41.50.9-0.5-0.50.8-0.9
Bone: trabecular spacing0.50.81.50.8-0.9-1.21.2-1.21.21.21.2-0.7-0.6-0.61.0-1.0-1.0-1.00.3-0.20.0-0.7-0.60.4-0.3
Bone: trabecular thickness0.30.41.0-0.50.50.7-0.71.0-1.0-1.0-0.90.50.50.3-0.80.80.80.8-0.10.1-0.00.70.6-0.30.3
Bone: trabecular tissue density1.72.95.4-0.80.81.9-2.02.2-2.2-2.2-2.20.1-0.0-0.3-2.12.22.32.30.7-0.9-0.92.12.0-1.71.6
Water consumed over 24 hours0.10.30.8-0.90.90.5-0.50.6-0.5-0.5-0.50.70.70.7-0.40.40.40.2-0.60.50.5-0.0-0.00.2-0.2
Number of responses in last shaping day0.70.91.6-0.10.10.8-0.71.0-1.0-1.0-1.0-0.3-0.4-0.5-1.21.21.21.20.7-0.9-1.01.21.2-1.01.1