Hub : Genes

Rab6a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA isoform ratio NM_053366.2 0.06 0.05 4.2e-03 0.02 0.04 0.04 0.03 2.0e-02 3.8e-03 2.9e-03 6.2e-03
2 BLA isoform ratio NM_001414455.1 0.05 0.04 8.9e-03 0.02 0.03 0.04 0.03 2.8e-02 9.3e-03 5.7e-03 1.2e-02
3 PL isoform ratio NM_001414455.1 0.03 0.02 1.5e-03 0 0.01 0.02 0.01 1.3e-01 7.7e-03 2.7e-03 2.0e-02
4 PL isoform ratio NM_053366.2 0.03 0.03 4.2e-04 0.02 0.02 0.03 0.02 1.7e-03 2.1e-03 5.4e-04 4.6e-03
5 PL intron excision ratio chr1_164394215_164396320 0.02 0.02 7.4e-03 0.01 0.02 0.01 0.01 1.5e-02 6.1e-03 3.0e-02 1.3e-02
6 PL intron excision ratio chr1_164394387_164396320 0.02 0.02 7.9e-03 0.01 0.02 0.01 0.01 1.4e-02 5.8e-03 2.0e-02 1.3e-02
7 Adipose mRNA stability Rab6a 0.03 0.02 1.3e-03 0.02 0.02 0.02 0.01 2.3e-03 2.0e-03 3.2e-03 7.1e-03
8 PL mRNA stability Rab6a 0.03 0.02 1.9e-03 0.01 0.03 0.01 0.01 1.3e-02 7.8e-04 3.2e-02 1.3e-02
9 NAcc mRNA stability Rab6a 0.04 0.03 6.5e-05 0.01 0.02 0.02 0.02 4.0e-03 1.9e-04 2.2e-04 3.0e-04
10 pVTA mRNA stability Rab6a 0.13 0.11 1.2e-04 0.05 0.06 0.04 0.05 1.4e-04 3.3e-05 5.3e-04 6.3e-05
11 Brain mRNA stability Rab6a 0.21 0.1 1.1e-14 0.13 0.16 0.15 0.15 1.9e-12 1.0e-14 1.3e-13 4.4e-14
12 NAcc isoform ratio NM_053366.2 0.02 0.01 3.7e-03 0.02 0.01 0.01 0.01 2.3e-04 4.4e-03 2.5e-03 1.9e-03
13 OFC mRNA stability Rab6a 0.22 0.13 2.3e-04 0.14 0.12 0.07 0.1 3.3e-04 9.2e-04 8.1e-03 2.7e-03
14 Liver mRNA stability Rab6a 0.18 0.1 1.6e-15 0.11 0.11 0.11 0.11 1.5e-12 4.7e-12 6.5e-12 7.2e-12
15 pVTA gene expression Rab6a 0.06 0.04 6.4e-05 0.03 0.04 0.03 0.02 9.9e-04 3.7e-04 1.5e-03 4.8e-03
16 BLA gene expression Rab6a 0.13 0.08 6.4e-04 0.04 0.04 0.04 0.04 5.9e-03 3.1e-03 4.7e-03 3.9e-03
17 PL gene expression Rab6a 0.11 0.07 6.7e-08 0.07 0.06 0.06 0.06 1.1e-07 6.1e-07 3.0e-07 1.0e-06
18 Brain gene expression Rab6a 0.38 0.19 0.0e+00 0.19 0.2 0.21 0.2 3.0e-17 1.8e-18 4.6e-19 3.8e-18
19 NAcc gene expression Rab6a 0.17 0.08 0.0e+00 0.15 0.21 0.21 0.21 1.5e-22 1.7e-31 8.2e-31 9.2e-31
20 OFC gene expression Rab6a 0.33 0.16 3.0e-06 0.07 0.18 0.14 0.13 1.0e-02 5.3e-05 3.9e-04 4.5e-04
21 IC gene expression Rab6a 0.33 0.13 1.1e-09 0.17 0.17 0.19 0.19 1.3e-07 8.6e-08 1.7e-08 2.9e-08
22 IL gene expression Rab6a 0.54 0.17 4.9e-09 0.1 0.23 0.19 0.21 2.3e-03 3.6e-06 3.2e-05 1.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.20.41.10.6-0.7-0.10.10.1-0.1-0.1-0.00.90.90.9-0.20.10.0-0.3-0.9-1.0-0.5-0.6-0.6-0.8-0.8
Area under the delay curve0.10.10.20.4-0.3-0.40.30.3-0.3-0.4-0.3-0.1-0.0-0.10.3-0.4-0.40.40.20.30.50.40.40.20.3
BMI with tail0.82.76.4-0.10.2-1.41.40.9-0.9-1.0-1.1-1.6-1.7-1.71.5-1.3-1.21.72.02.22.52.02.12.42.2
BMI without tail1.13.47.9-1.21.3-0.50.70.2-0.3-0.4-0.6-2.5-2.6-2.61.1-1.0-0.91.52.82.82.62.12.22.72.6
Body weight1.14.910.4-1.21.3-0.81.00.9-1.0-1.1-1.3-2.5-2.7-2.81.9-1.7-1.82.33.13.22.62.82.93.23.2
Weight adjusted by age0.30.41.3-0.40.4-0.10.10.1-0.1-0.1-0.2-0.8-0.8-0.90.4-0.2-0.40.50.90.91.10.70.70.80.9
Bone surface0.30.61.4-1.21.21.1-1.0-0.90.90.90.9-0.9-0.8-0.8-0.70.70.6-0.50.60.60.5-0.2-0.2-0.00.1
Bone volume0.10.30.6-0.80.80.8-0.8-0.60.60.60.6-0.5-0.4-0.5-0.50.50.4-0.40.30.20.3-0.2-0.2-0.20.0
Breakpoint value in progressive ratio session0.80.92.61.2-1.2-0.70.80.6-0.6-0.6-0.41.61.61.50.1-0.2-0.2-0.1-1.4-1.3-1.2-0.5-0.6-1.0-1.0
Number of licking bursts2.64.38.12.4-2.4-2.62.62.8-2.8-2.8-2.81.41.21.12.6-2.7-2.52.3-0.4-0.10.31.71.71.11.0
Context. condit. distance diff. score2.12.54.9-1.61.52.2-2.2-2.12.12.12.1-0.8-0.5-0.5-2.02.02.0-1.8-0.0-0.3-0.8-1.5-1.4-1.2-1.0
Locomotion velocity, session 10.60.71.50.9-0.9-0.20.2-0.10.10.10.21.11.21.2-0.40.40.4-0.7-1.2-1.2-1.0-0.9-0.9-1.1-1.1
Locomotion distance, session 10.91.22.0-1.01.01.3-1.3-1.41.41.41.4-0.2-0.1-0.0-1.41.41.4-1.4-0.3-0.5-0.9-1.2-1.1-1.0-0.9
Locomotion velocity, session 20.10.10.6-0.70.70.5-0.5-0.20.20.20.2-0.4-0.4-0.4-0.10.10.0-0.10.30.30.10.10.10.10.2
Locomotion distance, session 20.40.61.6-0.80.81.2-1.3-0.90.90.90.9-0.4-0.2-0.3-0.90.91.0-0.80.0-0.1-0.3-0.6-0.6-0.6-0.4
Locomotion velocity, session 31.01.12.1-0.90.80.9-0.7-1.21.21.21.30.10.30.2-1.41.41.4-1.3-0.6-0.8-1.3-1.2-1.2-1.0-1.1
Locomotion distance, session 31.71.83.2-0.70.71.4-1.4-1.61.61.61.70.10.30.4-1.81.81.7-1.8-0.7-1.0-1.0-1.7-1.6-1.5-1.4
Stereotopy head waving bouts, day 30.50.61.2-0.0-0.0-0.60.71.0-1.0-1.0-1.0-0.1-0.2-0.31.1-1.1-1.01.10.50.60.31.11.00.90.9
Stereotopy head waving duration, day 30.10.20.5-0.50.40.5-0.5-0.50.50.50.5-0.1-0.0-0.0-0.50.50.7-0.5-0.1-0.2-0.5-0.4-0.4-0.3-0.3
Locomotion velocity, session 70.20.20.60.4-0.50.1-0.20.2-0.2-0.2-0.10.80.70.80.0-0.00.1-0.2-0.7-0.7-0.3-0.4-0.4-0.7-0.6
Locomotion distance, session 70.10.10.30.5-0.5-0.0-0.20.5-0.5-0.5-0.50.30.30.30.4-0.4-0.40.4-0.2-0.10.40.30.2-0.20.1
Stereotopy head waving bouts, day 72.42.74.8-2.02.02.1-1.9-2.22.22.22.2-0.9-0.7-0.6-2.02.02.0-1.90.1-0.2-0.7-1.5-1.4-0.9-0.9
Stereotopy head waving duration, day 72.12.65.0-2.02.01.9-1.7-2.22.22.22.2-1.3-1.1-1.0-1.92.02.0-1.70.60.3-0.1-1.2-1.1-0.5-0.5
Locomotion velocity, session 80.70.92.1-1.51.41.4-1.3-1.11.11.11.1-0.5-0.4-0.4-1.01.01.1-0.90.20.0-0.7-0.7-0.6-0.5-0.4
Locomotion distance, session 81.92.75.6-2.01.92.4-2.3-2.22.12.12.1-1.1-0.9-0.9-1.91.92.1-1.70.40.1-0.5-1.2-1.2-0.9-0.7
Degree of sensitization distance2.32.44.60.1-0.1-0.80.71.5-1.6-1.6-1.7-0.8-1.0-1.01.9-1.9-1.82.11.41.61.72.12.11.82.0
Degree of sensitization stereotypy4.24.68.8-2.52.52.7-2.5-3.03.03.02.9-1.4-1.1-1.1-2.72.72.6-2.50.40.0-0.5-1.8-1.7-1.1-1.0
Conditioned locomotion0.30.41.60.3-0.3-0.20.3-0.00.00.00.20.80.90.7-0.40.40.4-0.4-0.9-0.8-1.3-0.5-0.7-0.7-0.8
Cocaine response after cond. corrected1.82.24.31.5-1.4-2.02.11.8-1.8-1.8-1.80.50.30.31.8-1.8-2.01.70.20.41.01.41.41.21.0
Cocaine response after cond. not corrected0.50.61.31.1-1.0-1.11.20.8-0.8-0.8-0.90.30.20.30.8-0.8-1.00.7-0.00.00.70.50.60.50.4
Cocaine response before conditioning2.12.55.0-1.01.01.7-1.6-2.12.12.12.1-0.4-0.20.0-2.12.12.2-2.1-0.5-0.7-0.7-1.9-1.7-1.3-1.3
Saline control response1.21.65.9-2.42.31.7-1.6-1.21.21.21.1-1.7-1.6-1.6-0.80.80.6-0.51.31.10.50.10.10.50.6
Bone: connectivity density0.30.51.10.4-0.40.1-0.2-0.40.40.40.40.70.70.9-0.70.60.6-0.8-0.9-1.0-0.5-1.0-0.9-1.0-1.0
Bone: cortical apparent density1.42.03.81.3-1.4-1.91.91.9-1.9-1.9-1.90.90.80.71.6-1.7-1.91.6-0.3-0.10.21.21.10.70.7
Bone: cortical area0.20.30.8-0.80.80.10.1-0.00.0-0.0-0.0-0.8-0.8-0.90.2-0.2-0.30.40.90.90.60.60.60.70.7
Bone: cortical porosity0.91.01.8-0.10.20.8-0.7-1.21.21.21.20.20.40.4-1.21.31.4-1.3-0.7-0.8-0.7-1.3-1.3-1.1-1.2
Bone: cortical porosity1.01.12.0-0.30.30.9-0.8-1.31.31.31.30.10.30.3-1.31.31.4-1.4-0.7-0.8-0.6-1.4-1.3-1.1-1.2
Bone: cortical thickness0.20.30.70.5-0.6-0.80.80.6-0.6-0.6-0.60.80.80.70.4-0.4-0.60.3-0.6-0.6-0.60.0-0.0-0.2-0.3
Bone: cortical thickness0.10.10.3-0.50.50.4-0.4-0.40.40.40.5-0.10.1-0.0-0.50.50.4-0.4-0.1-0.2-0.4-0.3-0.4-0.4-0.3
Bone: cortical tissue density1.31.83.51.4-1.4-1.81.81.9-1.9-1.9-1.81.00.90.81.5-1.6-1.81.5-0.4-0.20.11.11.00.60.5
Condit. Reinf. active minus inactive responses0.40.40.9-1.00.90.3-0.30.0-0.0-0.1-0.1-0.9-0.9-0.90.3-0.3-0.40.51.00.90.60.70.70.80.8
Condit. Reinf. active-inactive response ratio0.70.71.6-1.21.20.7-0.7-0.20.20.20.1-1.3-1.3-1.30.1-0.2-0.30.41.31.21.00.70.80.81.0
Condit. Reinf. active responses0.10.20.3-0.50.50.1-0.10.2-0.2-0.2-0.2-0.4-0.4-0.50.3-0.3-0.50.40.50.50.10.50.50.50.5
Condit. Reinf. inactive responses0.10.10.60.3-0.3-0.30.30.1-0.1-0.1-0.10.40.40.3-0.00.0-0.0-0.1-0.4-0.3-0.8-0.1-0.2-0.2-0.3
Incentive salience index mean0.30.41.0-1.00.90.5-0.5-0.10.10.10.0-0.9-0.9-0.90.1-0.1-0.30.30.90.90.60.60.60.60.7
Condit. Reinf. lever presses0.10.20.7-0.90.80.6-0.7-0.40.40.40.3-0.6-0.5-0.5-0.30.3-0.1-0.10.50.40.20.00.10.10.2
Condit. Reinf. active minus inactive responses4.55.915.5-3.93.93.1-3.1-2.52.42.42.2-3.3-3.1-3.1-1.71.71.5-1.02.62.31.30.10.20.81.1
Condit. Reinf. active-inactive response ratio0.91.12.1-1.41.51.4-1.4-1.21.21.21.1-1.3-1.2-1.2-0.90.90.8-0.61.00.90.7-0.2-0.10.20.3
Condit. Reinf. active responses6.28.623.6-4.94.83.7-3.8-2.92.82.72.5-4.2-3.9-4.0-1.81.81.6-0.93.43.01.70.40.51.21.6
Condit. Reinf. inactive responses3.64.714.3-3.83.72.6-2.6-1.91.81.71.6-3.1-3.0-3.0-1.11.10.9-0.42.62.41.20.60.61.11.4
Condit. Reinf. lever presses10.815.034.6-5.95.95.3-5.3-4.54.44.44.1-4.9-4.5-4.5-3.43.33.2-2.43.52.91.6-0.8-0.50.41.0
Condit. Reinf. lever reinforcers received7.09.726.0-5.15.04.1-4.0-3.13.03.02.8-4.3-4.1-4.1-2.12.01.8-1.13.43.11.80.20.41.11.6
Conditioned reinforcement - actives1.01.83.3-1.31.31.4-1.4-1.81.81.81.8-0.5-0.2-0.2-1.71.81.8-1.6-0.2-0.3-1.0-1.4-1.4-1.0-1.0
Conditioned reinforcement - inactives0.10.20.70.4-0.5-0.40.40.3-0.3-0.3-0.20.60.50.50.3-0.10.00.0-0.5-0.4-0.9-0.1-0.2-0.2-0.3
Conditioned locomotion3.14.17.6-1.21.22.3-2.4-2.52.52.52.6-0.10.20.3-2.72.82.4-2.6-0.9-1.1-1.5-2.4-2.3-2.1-1.9
Patch foraging indifference point 0 sec1.73.26.0-2.32.32.0-2.0-2.52.42.42.3-1.9-1.6-1.6-2.12.02.3-1.61.00.80.3-1.0-0.9-0.2-0.2
Patch foraging indifference point AUC0.60.92.2-0.90.9-0.10.10.4-0.4-0.5-0.5-1.0-1.0-1.10.9-0.8-0.80.91.21.21.51.21.21.21.3
Delay disc. indifference point, 0s delay0.60.71.6-1.21.31.0-1.0-0.90.90.90.8-1.2-1.1-1.1-0.70.60.6-0.40.90.90.40.00.00.30.4
Delay disc. indifference point, 16s delay0.10.11.01.0-0.9-0.40.30.2-0.2-0.2-0.20.40.50.40.0-0.1-0.10.0-0.4-0.3-0.2-0.1-0.1-0.3-0.2
Delay disc. indifference point, 2s delay0.60.71.7-0.90.90.6-0.6-0.40.30.30.2-1.3-1.3-1.3-0.0-0.1-0.10.31.31.21.00.60.70.80.9
Delay disc. indifference point, 24s delay0.91.03.31.8-1.7-1.41.41.1-1.1-1.1-1.01.11.11.00.7-0.8-0.80.6-0.8-0.6-0.50.30.2-0.1-0.2
Delay disc. indifference point, 4s delay1.21.23.1-1.51.50.4-0.3-0.30.20.20.1-1.7-1.6-1.80.1-0.2-0.30.61.71.71.41.01.11.31.4
Delay disc. indifference point, 8s delay0.00.00.30.0-0.0-0.20.00.1-0.1-0.2-0.2-0.00.1-0.00.1-0.2-0.20.20.10.10.50.10.1-0.00.1
Indifference point function ln k1.62.75.1-0.30.31.4-1.4-1.91.91.92.00.30.70.6-2.22.12.1-2.2-1.1-1.2-1.9-2.1-2.1-1.9-1.8
Indifference point function log k1.62.75.1-0.30.31.4-1.4-1.91.91.92.00.30.70.6-2.22.12.1-2.2-1.1-1.2-1.9-2.1-2.1-1.9-1.8
Patch foraging total patch changes 0 sec1.42.64.8-2.22.21.8-1.8-2.22.12.12.0-1.8-1.6-1.5-1.81.72.0-1.41.10.90.5-0.8-0.7-0.0-0.0
Patch foraging total patch changes 12 sec1.11.43.3-1.61.60.4-0.3-0.40.30.30.2-1.8-1.7-1.80.2-0.2-0.00.51.81.71.71.01.11.41.4
Patch foraging total patch changes 18 sec1.21.84.9-2.22.21.3-1.3-1.41.41.41.2-2.0-1.9-1.8-0.80.80.9-0.51.61.51.20.10.20.70.7
Patch foraging total patch changes 24 sec0.81.43.2-1.71.70.6-0.7-0.40.40.40.2-1.8-1.8-1.80.1-0.10.00.51.71.61.80.91.01.31.3
Patch foraging total patch changes 6 sec0.30.51.0-1.01.00.6-0.6-0.90.90.90.8-0.8-0.6-0.7-0.80.70.9-0.50.50.40.3-0.3-0.20.10.0
Patch foraging time to switch 0 sec1.53.06.32.5-2.5-2.32.32.1-2.1-2.0-1.92.32.12.01.6-1.5-1.51.1-1.6-1.3-1.10.40.3-0.3-0.4
Patch foraging water rate 0 sec1.32.75.1-1.92.02.2-2.1-2.32.22.22.1-1.8-1.5-1.5-2.01.91.9-1.51.00.70.3-0.9-0.8-0.2-0.2
Patch foraging water rate 12 sec1.12.34.3-1.61.61.9-1.9-2.12.12.12.0-1.0-0.8-0.7-1.92.01.8-1.70.2-0.1-0.5-1.4-1.3-0.8-0.8
Patch foraging water rate 18 sec0.81.33.1-1.81.81.6-1.6-1.21.21.21.1-1.5-1.4-1.3-1.00.90.9-0.61.10.70.7-0.1-0.00.20.4
Patch foraging water rate 24 sec1.41.93.5-0.60.61.2-1.2-1.71.71.71.80.00.20.3-1.91.81.8-1.8-0.7-1.0-1.4-1.7-1.7-1.3-1.4
Patch foraging water rate 6 sec0.91.43.4-1.01.01.8-1.8-1.51.51.51.5-0.5-0.4-0.3-1.41.51.5-1.4-0.1-0.4-0.1-1.1-1.1-0.9-0.7
Seeking ratio, delayed vs. immediate footshock0.81.02.41.5-1.5-1.31.30.8-0.8-0.7-0.71.51.31.50.5-0.4-0.30.1-1.3-1.3-0.4-0.4-0.4-0.7-0.8
Distance traveled before self-admin0.50.61.40.6-0.7-0.90.81.2-1.2-1.2-1.10.70.70.61.0-1.0-1.10.9-0.3-0.20.30.60.60.20.2
Distance traveled after self-admin1.21.54.10.6-0.60.2-0.2-0.10.10.20.31.71.81.7-0.60.60.6-0.9-1.8-1.9-2.0-1.3-1.4-1.7-1.7
Extensor digitorum longus weight0.62.34.30.3-0.3-1.41.41.2-1.3-1.3-1.4-0.9-1.1-1.11.6-1.6-1.71.81.51.72.11.91.92.01.9
Bone: elastic displacement1.41.64.01.7-1.8-1.31.31.1-1.1-1.0-1.02.01.91.90.7-0.7-0.70.2-1.7-1.5-1.3-0.4-0.5-0.8-1.0
Bone: elastic work1.52.05.12.3-2.2-1.71.71.0-1.0-0.9-0.92.12.02.10.6-0.5-0.50.0-1.9-1.7-0.9-0.7-0.7-0.9-1.2
Bone: endosteal estimation1.22.56.5-1.71.80.9-0.9-0.80.70.60.5-2.5-2.5-2.5-0.00.10.00.52.42.42.41.21.31.71.8
Bone: endosteal perimeter1.32.87.1-2.12.21.2-1.2-1.11.00.90.8-2.7-2.6-2.6-0.30.30.20.22.52.42.21.01.11.61.7
Epididymis fat weight0.31.12.51.2-1.1-1.51.51.3-1.3-1.3-1.30.50.40.31.6-1.1-1.21.20.00.30.70.90.90.60.6
Delta time in closed arm before/after self-admin3.23.05.41.1-1.1-2.12.01.9-2.0-2.0-2.1-0.2-0.5-0.52.3-2.2-2.22.21.01.21.72.02.01.81.8
Delta time in open arm before/after self-admin1.71.73.7-1.91.91.9-1.7-1.61.51.51.4-1.6-1.6-1.5-1.11.21.2-0.91.10.90.2-0.3-0.20.20.3
Diff in mean of infusions in LGA sessions2.32.85.71.5-1.6-2.02.02.4-2.3-2.3-2.22.01.71.72.1-2.0-2.01.5-1.2-1.1-0.80.90.70.1-0.0
Delay discount exponential model param0.10.10.3-0.40.40.5-0.4-0.30.30.40.40.10.10.1-0.30.40.4-0.4-0.3-0.3-0.6-0.4-0.4-0.3-0.4
Extinction: sum of active levers before priming0.10.10.2-0.30.2-0.10.20.0-0.0-0.0-0.1-0.3-0.4-0.40.2-0.2-0.20.20.40.4-0.10.30.30.30.3
Active lever presses in extinction session 64.84.78.4-0.40.42.2-2.3-2.12.22.22.30.91.31.2-2.82.62.5-2.7-1.8-1.9-2.2-2.7-2.8-2.9-2.6
Bone: final force0.10.10.60.8-0.7-0.50.60.4-0.4-0.4-0.40.30.30.20.3-0.3-0.20.3-0.2-0.10.20.20.10.00.0
Bone: final moment0.00.10.40.6-0.5-0.30.40.2-0.2-0.2-0.20.10.10.10.2-0.2-0.00.2-0.0-0.00.40.20.10.10.1
Food consumed during 24 hour testing period2.53.46.7-1.92.02.6-2.6-2.52.52.52.5-1.2-1.0-0.9-2.32.32.3-2.10.30.0-0.3-1.6-1.5-1.1-0.9
Glucose0.00.00.2-0.0-0.0-0.30.50.1-0.1-0.1-0.20.0-0.0-0.00.2-0.2-0.20.10.10.20.10.10.20.30.1
Heart weight0.50.81.6-1.31.21.1-0.9-1.31.31.21.2-0.7-0.6-0.6-1.01.21.1-1.00.30.3-0.4-0.7-0.6-0.3-0.3
Delay discount hyperbolic model param0.20.20.7-0.20.10.4-0.3-0.30.30.40.40.40.30.4-0.40.50.5-0.6-0.5-0.6-0.8-0.6-0.6-0.5-0.6
Intermittent access intake day 1-15 change0.40.71.7-1.00.91.0-1.0-1.01.01.11.1-0.2-0.1-0.1-1.31.21.0-1.0-0.2-0.4-0.9-0.9-0.8-0.6-0.6
Intermittent access intake escalation0.51.02.0-1.21.11.2-1.1-1.21.21.31.2-0.3-0.2-0.1-1.41.31.2-1.2-0.2-0.4-0.9-1.0-0.9-0.7-0.7
Intermittent access intake escalation 20.40.41.0-0.90.90.6-0.6-0.90.90.90.8-0.7-0.5-0.5-1.00.80.7-0.60.30.1-0.1-0.4-0.30.0-0.1
Intermitt. access day 1 inactive lever presses0.31.22.21.4-1.4-1.51.41.4-1.4-1.4-1.40.70.50.51.3-1.2-1.21.2-0.20.10.10.90.80.60.5
Intermitt. access day 15 inactive lever presses0.30.72.20.7-0.8-0.00.10.4-0.4-0.3-0.21.41.41.30.1-0.1-0.0-0.3-1.3-1.1-1.5-0.6-0.7-1.1-1.0
Intermitt. access escalation Index0.00.00.60.1-0.00.1-0.1-0.10.10.10.1-0.2-0.2-0.2-0.20.10.1-0.00.20.10.70.00.10.00.1
Intermittent access day 1 total infusions1.11.84.2-1.81.82.0-2.0-1.71.71.71.7-0.8-0.7-0.6-1.21.51.6-1.40.20.1-0.6-1.1-1.0-0.9-0.7
Intermittent access day 15 total infusions1.52.24.0-2.01.82.0-1.9-1.91.91.91.9-0.6-0.4-0.4-1.71.81.8-1.7-0.1-0.3-1.1-1.4-1.3-1.1-1.0
Intermittent access terminal intake (last 3 days)1.82.34.5-2.12.02.0-2.0-1.91.91.91.9-0.9-0.7-0.7-2.01.91.7-1.60.30.0-0.7-1.2-1.1-0.8-0.7
Intermittent access total infusions1.61.94.3-2.12.02.0-2.0-1.71.71.71.7-1.2-1.1-1.0-1.31.51.5-1.30.60.4-0.5-0.8-0.8-0.5-0.3
Intermittent access day 1 locomotion0.60.71.4-0.70.61.2-1.2-0.90.90.91.00.20.20.3-0.71.00.9-1.0-0.5-0.4-1.0-1.0-1.0-1.1-0.9
Intermittent access day 15 total locomotion1.12.03.4-0.70.71.7-1.7-1.71.71.71.70.10.20.3-1.61.81.6-1.8-0.7-0.8-1.3-1.7-1.7-1.6-1.4
Intermittent access total locomotion1.11.33.2-1.21.11.8-1.7-1.41.41.41.4-0.3-0.2-0.1-1.11.41.2-1.3-0.2-0.3-1.2-1.1-1.1-1.1-0.9
Intermittent access standard deviation0.10.31.0-0.50.4-0.00.10.1-0.1-0.2-0.2-0.7-0.7-0.80.2-0.2-0.40.50.91.00.40.70.70.80.8
Left kidney weight0.52.24.9-0.90.9-0.50.60.4-0.5-0.5-0.7-1.8-1.9-2.01.1-1.0-1.01.42.12.22.21.81.92.22.1
Right kidney weight0.83.58.2-1.11.2-0.30.30.4-0.5-0.6-0.8-2.4-2.5-2.51.2-1.1-1.11.72.72.82.92.22.32.62.7
Cocaine induced anxiety1.11.64.92.2-2.2-1.71.61.4-1.4-1.4-1.31.51.51.41.0-1.1-1.10.8-1.1-0.8-0.40.30.2-0.2-0.3
Post-drug Anxiety1.51.62.81.7-1.7-1.61.61.7-1.7-1.7-1.61.31.21.11.4-1.4-1.41.1-0.7-0.5-0.40.70.60.20.1
Baseline Anxiety0.30.31.4-1.21.10.7-0.6-0.30.30.30.3-0.7-0.8-0.8-0.00.10.10.00.70.50.00.30.30.40.4
Tail length1.45.412.2-2.52.40.5-0.30.3-0.4-0.4-0.6-3.1-3.3-3.41.3-1.3-1.41.93.53.42.52.72.83.13.2
Length with tail0.93.88.3-2.42.30.8-0.50.3-0.4-0.4-0.5-2.5-2.7-2.81.3-1.1-1.31.62.92.81.72.32.32.52.6
Length without tail0.10.20.7-0.30.20.1-0.10.6-0.6-0.6-0.60.1-0.0-0.10.9-0.6-0.70.60.20.3-0.20.60.50.20.4
Times rat made contact with spout0.70.81.50.4-0.4-0.70.71.0-1.0-1.0-1.0-0.3-0.4-0.51.1-1.2-1.21.20.80.71.01.21.21.11.1
Lifetime Intake1.92.35.1-2.22.22.3-2.2-2.01.92.01.9-1.3-1.2-1.0-1.41.71.7-1.50.60.3-0.6-1.0-0.9-0.6-0.4
Liver weight, left0.91.63.00.00.0-1.00.90.9-1.0-1.0-1.1-1.0-1.1-1.11.2-1.3-1.21.51.41.51.61.61.71.71.7
Liver weight, right2.23.86.30.4-0.4-2.02.02.0-2.0-2.1-2.1-0.7-1.0-1.12.3-2.3-2.22.51.61.81.92.52.52.52.3
Locomotor activity0.30.51.1-0.70.80.7-0.7-0.90.90.90.9-0.4-0.2-0.4-1.00.91.0-0.80.10.10.0-0.6-0.6-0.4-0.3
Locomotor testing distance0.81.43.3-1.81.81.3-1.2-1.31.21.21.1-1.7-1.5-1.6-1.00.80.8-0.51.31.21.00.10.10.50.6
Locomotor testing rearing0.51.12.5-1.51.40.4-0.3-0.20.10.10.0-1.5-1.4-1.60.2-0.3-0.40.61.61.61.21.01.01.21.3
Locomotion in novel chamber0.91.13.50.3-0.20.7-0.8-1.11.21.11.20.30.60.5-1.91.21.3-1.3-0.8-0.8-0.8-1.4-1.4-1.3-1.2
Locomotion in novel chamber post-restriction1.32.24.1-1.51.52.0-2.0-2.02.02.02.0-0.8-0.7-0.5-1.81.81.8-1.70.1-0.1-0.1-1.4-1.3-0.9-0.8
Fecal boli incidents, locomotor time 10.71.12.4-0.10.20.8-1.1-1.21.21.21.20.10.30.4-1.51.51.4-1.3-0.7-0.8-0.6-1.3-1.3-1.3-1.1
Change in fecal boli incidents, locomotor task0.50.51.00.6-0.6-0.70.81.0-0.9-0.9-0.90.40.20.21.0-1.0-0.90.8-0.00.00.40.70.60.50.4
Time >=10cm from walls, locomotor time 11.51.63.3-1.01.01.5-1.6-1.71.71.71.7-0.6-0.4-0.3-1.81.81.7-1.5-0.1-0.3-0.3-1.3-1.3-1.0-0.9
Bouts of movement, locomotor time 10.20.20.9-1.00.80.3-0.4-0.50.50.50.5-0.2-0.1-0.2-0.60.60.5-0.40.00.0-0.5-0.3-0.3-0.3-0.2
Total resting periods, locomotor time 10.40.50.9-0.60.50.5-0.6-0.60.60.60.70.30.50.4-0.80.90.8-0.8-0.6-0.6-0.9-0.8-0.9-0.9-0.8
Rest time, locomotor task time 10.50.71.9-0.10.00.4-0.6-0.30.40.40.50.90.91.0-0.50.60.7-0.8-1.1-1.0-1.4-1.0-1.0-1.2-1.1
Distance moved, locomotor task time 10.71.02.80.1-0.0-0.80.90.4-0.5-0.5-0.6-1.0-1.0-1.10.7-0.8-0.81.01.31.31.71.21.31.51.4
Vertical activity count, locomotor time 10.20.51.5-0.40.40.10.0-0.0-0.0-0.0-0.1-1.1-1.1-1.10.3-0.4-0.20.51.11.11.20.80.81.01.0
Time >=10cm from walls, locomotor time 20.71.12.9-1.71.71.2-1.1-1.21.21.11.1-1.4-1.3-1.3-0.80.80.9-0.51.00.80.1-0.1-0.10.30.3
Bouts of movement, locomotor time 20.60.92.1-0.70.7-0.60.70.1-0.2-0.2-0.3-1.3-1.3-1.40.3-0.4-0.60.81.41.51.21.21.11.41.4
Total resting periods, locomotor time 20.40.81.8-0.30.3-0.91.00.4-0.4-0.5-0.5-0.9-0.9-1.10.5-0.6-0.70.91.11.21.01.11.11.31.2
Rest time, locomotor task time 21.41.83.11.7-1.7-1.61.61.7-1.7-1.6-1.61.81.51.61.6-1.4-1.20.9-1.2-1.0-1.00.40.3-0.2-0.3
Distance moved, locomotor task time 21.51.84.5-2.12.11.1-1.0-1.51.51.51.4-2.0-1.8-1.9-1.21.01.1-0.61.51.40.8-0.00.10.70.6
Vertical activity count, locomotor time 20.50.72.2-1.01.00.5-0.5-0.70.70.60.6-1.5-1.4-1.4-0.30.20.40.01.31.30.70.40.50.90.8
Light reinforcement 11.23.08.02.4-2.4-2.82.82.1-2.1-2.1-2.11.61.31.41.9-1.8-1.71.5-0.9-0.60.10.90.80.60.2
Light reinforcement 20.30.41.01.0-1.0-0.50.60.2-0.2-0.1-0.10.90.81.00.00.10.2-0.3-0.9-1.0-0.1-0.6-0.5-0.5-0.7
Bone: marrow area1.12.35.9-1.51.60.7-0.7-0.60.50.50.3-2.4-2.4-2.40.1-0.1-0.10.62.42.42.41.21.31.71.8
Bone: maximum diameter1.01.94.8-2.22.21.0-0.8-1.01.01.00.8-2.1-2.1-2.1-0.50.50.3-0.01.91.81.30.60.71.21.2
Bone: maximum force0.00.00.20.5-0.4-0.30.40.2-0.2-0.2-0.20.20.20.20.1-0.10.00.1-0.1-0.10.30.10.0-0.0-0.0
Bone: maximum moment0.00.00.20.3-0.2-0.10.20.0-0.0-0.0-0.0-0.0-0.0-0.10.0-0.00.10.00.00.00.50.10.00.10.1
Mean time between licks in bursts1.84.411.2-3.13.11.2-1.0-1.11.00.90.8-3.3-3.2-3.4-0.20.20.10.53.12.92.41.51.52.22.3
Mean num. licks in bursts2.13.36.3-2.12.12.5-2.4-2.52.52.52.4-1.5-1.2-1.1-2.22.32.1-1.90.60.2-0.0-1.4-1.3-0.8-0.7
Cd content in liver0.70.71.20.4-0.4-0.80.90.9-0.9-0.9-1.0-0.2-0.4-0.41.1-1.1-1.11.10.60.70.71.11.11.00.9
Co content in liver0.91.12.7-1.51.51.0-1.0-0.70.70.60.6-1.6-1.6-1.6-0.30.30.30.11.51.40.80.60.60.81.0
Cu content in liver1.41.63.9-1.31.30.1-0.00.2-0.3-0.3-0.4-1.7-1.8-1.80.8-0.8-0.61.11.92.01.41.51.51.81.8
Fe content in liver0.00.00.00.2-0.1-0.00.00.2-0.2-0.1-0.10.10.10.10.2-0.20.20.1-0.1-0.1-0.10.00.0-0.0-0.0
K content in liver0.40.40.70.1-0.1-0.40.50.6-0.6-0.7-0.7-0.3-0.3-0.40.8-0.8-0.80.80.50.70.00.80.80.80.7
Mg content in liver0.00.00.1-0.10.20.2-0.2-0.30.20.20.2-0.4-0.3-0.3-0.10.10.1-0.10.30.3-0.20.00.00.20.1
Mn content in liver1.11.23.01.6-1.6-0.70.70.4-0.4-0.4-0.31.71.71.7-0.00.00.1-0.4-1.6-1.6-1.2-0.9-0.9-1.2-1.3
Na content in liver0.40.51.1-1.00.91.1-0.9-0.90.80.90.8-0.6-0.5-0.5-0.60.60.9-0.60.30.2-0.5-0.4-0.3-0.2-0.2
Rb content in liver0.20.20.5-0.60.60.7-0.6-0.60.60.60.6-0.6-0.5-0.5-0.40.40.4-0.40.40.30.2-0.2-0.10.00.1
Se content in liver2.73.27.32.7-2.7-2.22.21.9-1.9-1.8-1.72.62.42.41.4-1.4-1.10.8-2.0-1.7-1.6-0.0-0.1-0.6-0.9
Sr content in liver0.40.30.6-0.20.20.4-0.4-0.60.60.60.60.20.30.3-0.60.60.8-0.8-0.5-0.6-0.6-0.8-0.7-0.7-0.7
Zn content in liver1.71.94.4-2.02.01.4-1.4-1.41.31.31.2-2.1-2.0-2.0-0.80.80.8-0.41.71.60.90.20.30.80.9
Bone: minimum diameter1.42.65.9-1.31.3-0.20.40.4-0.5-0.5-0.6-2.0-2.1-2.21.0-1.0-1.21.52.42.42.02.02.02.32.3
Time in familiar zone, hab. session 10.20.20.4-0.20.2-0.10.10.3-0.3-0.3-0.3-0.4-0.5-0.50.5-0.4-0.50.50.60.60.60.60.60.60.6
Time in novel zone, hab. session 10.20.20.40.3-0.4-0.60.50.6-0.5-0.5-0.50.40.40.40.4-0.4-0.30.4-0.3-0.2-0.50.20.20.10.0
Total zone transitions, hab. session 10.50.62.1-0.50.40.5-0.5-0.50.50.60.60.70.70.7-0.70.70.7-0.9-0.9-1.0-1.5-1.0-1.0-1.1-1.1
Total locomotion distance, hab. session 11.52.23.90.1-0.1-1.21.21.6-1.6-1.7-1.7-0.5-0.6-0.81.8-1.8-1.82.01.11.31.32.01.91.81.7
Locomotion velocity, hab. session 10.91.32.4-0.0-0.0-0.90.91.2-1.2-1.3-1.3-0.4-0.5-0.71.3-1.4-1.41.50.91.11.01.61.51.41.4
Time in familiar zone, hab. session 21.01.02.6-1.21.31.5-1.6-1.11.11.11.0-1.4-1.4-1.3-0.80.70.6-0.41.11.00.9-0.00.00.10.5
Time in novel zone, hab. session 20.40.40.90.6-0.7-0.70.80.4-0.4-0.4-0.31.01.01.00.1-0.1-0.0-0.1-0.9-0.8-0.9-0.3-0.3-0.3-0.6
Total zone transitions, hab. session 21.52.03.1-1.71.61.8-1.6-1.71.71.71.8-0.3-0.1-0.1-1.71.71.8-1.7-0.3-0.6-1.4-1.4-1.4-1.1-1.1
Total locomotion distance, hab. session 21.01.32.6-1.11.0-0.20.30.7-0.7-0.8-0.8-1.1-1.2-1.41.1-1.0-0.91.31.51.60.81.61.61.61.6
Locomotion velocity, hab. session 21.31.73.5-1.00.9-0.30.40.9-1.0-1.0-1.0-1.1-1.3-1.41.3-1.3-1.21.61.61.81.01.91.81.81.8
Novel to familiar place preference ratio0.10.10.8-0.40.40.2-0.1-0.20.20.20.3-0.10.0-0.1-0.30.30.4-0.2-0.0-0.1-0.9-0.1-0.2-0.0-0.1
Novelty place preference0.10.10.9-0.50.40.2-0.0-0.20.20.20.3-0.10.0-0.1-0.30.30.3-0.2-0.0-0.1-0.9-0.1-0.2-0.0-0.1
Time in novel zone, NPP test0.20.21.0-0.70.60.5-0.3-0.40.40.40.5-0.2-0.0-0.2-0.50.50.6-0.30.0-0.1-1.0-0.2-0.3-0.1-0.2
Total zone transitions, NPP test0.40.61.0-0.80.70.8-0.8-0.80.80.80.80.30.40.4-0.90.90.9-1.0-0.6-0.6-1.0-1.0-0.9-0.9-0.9
Total locomotion distance, NPP test1.11.42.7-0.10.0-1.01.01.2-1.3-1.3-1.3-0.5-0.6-0.71.4-1.4-1.41.61.01.21.01.61.61.51.5
Locomotion velocity, NPP test1.21.73.10.2-0.3-1.41.31.5-1.5-1.6-1.6-0.2-0.4-0.51.7-1.7-1.61.80.91.11.01.71.71.51.5
Intraocular pressure0.40.61.30.4-0.30.1-0.1-0.70.70.80.70.40.50.7-1.00.91.0-1.0-0.8-0.8-0.4-1.2-1.0-0.8-1.0
Delta distance traveled before/after self-admin2.32.44.1-1.31.21.7-1.6-1.81.91.91.9-0.10.10.1-1.92.02.0-1.9-0.6-0.8-1.8-1.7-1.7-1.4-1.4
Delta ambulatory time before/after self-admin2.02.54.4-1.01.01.7-1.6-1.91.91.91.9-0.00.20.3-2.02.12.1-2.0-0.7-0.9-1.8-1.8-1.8-1.6-1.5
Parametrial fat weight0.51.33.21.0-1.0-1.81.81.4-1.4-1.4-1.40.60.30.51.7-1.3-1.31.2-0.00.20.80.90.90.90.6
Pavlov. Cond. lever latency0.91.12.61.6-1.6-1.51.51.3-1.2-1.2-1.21.31.21.21.0-1.0-0.80.7-0.9-0.8-0.60.30.2-0.0-0.2
Pavlov. Cond. magazine entry latency2.22.87.0-2.12.22.5-2.6-1.91.91.91.8-2.1-2.0-1.9-1.41.41.3-1.01.51.31.2-0.3-0.20.00.4
Pavlov. Cond. change in total contacts1.01.12.7-1.51.51.6-1.6-1.21.21.21.1-1.3-1.2-1.2-0.80.80.9-0.60.90.80.6-0.2-0.1-0.00.2
Pavlov. Cond. index score1.82.35.0-2.12.12.2-2.2-1.81.71.71.6-2.0-1.8-1.8-1.31.31.1-0.91.41.21.2-0.3-0.10.10.5
Pavlov. Cond. latency score1.82.24.9-2.12.12.1-2.2-1.71.71.71.6-1.9-1.7-1.7-1.31.31.1-0.91.31.21.1-0.3-0.20.00.4
Pavlov. Cond. lever contacts0.81.02.2-1.51.51.3-1.3-1.11.11.11.0-1.4-1.3-1.2-0.80.80.6-0.51.00.90.9-0.10.00.20.4
Pavlov. Cond. magazine entry number2.22.86.72.2-2.3-2.52.62.0-1.9-1.9-1.82.12.01.91.5-1.5-1.41.1-1.5-1.2-1.20.40.3-0.0-0.4
Pavlov. Cond. intertrial magazine entries0.60.71.51.0-1.0-1.11.20.9-0.9-0.9-0.81.21.11.10.6-0.7-0.40.4-0.9-0.8-0.70.1-0.0-0.2-0.4
Pavlov. Cond. lever-magazine prob. diff.1.51.94.3-1.91.92.0-2.1-1.61.61.51.4-1.7-1.6-1.6-1.11.21.1-0.81.31.11.1-0.3-0.20.00.4
Pavlov. Cond. response bias1.11.33.3-1.61.61.7-1.8-1.31.31.31.2-1.5-1.4-1.3-0.90.90.8-0.71.10.90.8-0.2-0.10.00.3
Pavlov. Cond. lever latency11.615.735.96.0-6.0-5.45.34.9-4.8-4.7-4.54.74.34.23.8-3.7-3.62.8-3.2-2.5-1.21.21.0-0.1-0.5
Pavlov. Cond. magazine entry latency2.93.57.7-2.02.12.8-2.8-2.52.52.52.4-1.6-1.4-1.3-2.22.22.1-1.90.80.40.1-1.3-1.2-0.8-0.5
Pavlov. Cond. change in total contacts7.612.228.2-5.35.34.9-4.7-4.34.34.24.1-4.0-3.6-3.5-3.43.43.2-2.62.62.00.5-1.3-1.0-0.20.2
Pavlov. Cond. index score8.511.423.6-4.84.94.7-4.5-4.34.24.14.0-3.9-3.6-3.5-3.33.33.2-2.62.52.00.8-1.2-1.0-0.10.3
Pavlov. Cond. latency score7.510.020.5-4.54.54.3-4.2-4.04.03.93.8-3.6-3.3-3.2-3.23.23.1-2.52.31.70.7-1.3-1.0-0.20.2
Pavlov. Cond. lever contacts10.714.834.2-5.85.85.1-5.0-4.74.64.64.4-4.6-4.2-4.2-3.63.63.4-2.73.12.51.1-1.1-0.90.20.6
Pavlov. Cond. magazine entry number5.06.213.63.0-3.1-3.73.63.3-3.3-3.3-3.22.22.01.82.8-2.8-2.72.4-1.1-0.60.11.61.40.90.6
Pavlov. Cond. intertrial magazine entries0.91.43.1-0.80.7-0.60.70.6-0.6-0.7-0.7-1.2-1.3-1.41.0-1.0-1.01.21.51.71.31.51.51.81.6
Pavlov. Cond. lever-magazine prob. diff.7.910.521.9-4.74.74.5-4.4-4.04.03.93.7-3.9-3.6-3.5-3.13.13.0-2.32.62.00.9-1.0-0.80.00.4
Pavlov. Cond. response bias11.315.332.1-5.75.75.5-5.4-4.94.84.84.6-4.5-4.1-4.0-3.83.83.6-3.02.92.31.2-1.4-1.2-0.20.3
Time in closed arm before self-admin2.53.35.5-1.41.32.4-2.3-2.02.12.12.20.10.40.3-2.32.22.2-2.2-0.9-1.1-1.5-2.0-2.0-1.9-1.8
Time in closed arm after self-admin0.60.71.81.1-1.1-0.50.40.5-0.5-0.5-0.41.31.41.30.2-0.1-0.2-0.1-1.2-1.1-0.7-0.5-0.6-0.9-0.9
Time in open arm before self-admin3.13.48.92.7-2.6-3.02.92.2-2.2-2.2-2.21.31.21.11.8-2.1-2.01.7-0.6-0.30.51.11.10.90.6
Time in open arm after self-admin0.50.61.5-0.20.3-0.40.50.2-0.3-0.3-0.4-0.9-1.0-1.00.5-0.6-0.60.71.11.10.70.91.01.21.1
Bone: periosteal estimation0.91.84.6-1.51.60.6-0.5-0.60.50.50.3-2.1-2.1-2.20.0-0.0-0.10.52.12.12.01.01.11.51.6
Bone: periosteal perimeter1.01.64.1-1.71.70.7-0.6-0.70.60.60.5-2.0-2.0-2.0-0.10.1-0.00.31.91.91.60.91.01.41.4
Bone: post-yield work0.00.00.1-0.30.30.2-0.2-0.10.10.10.1-0.3-0.3-0.3-0.00.00.10.10.30.30.20.10.10.10.2
Progressive ratio test 1 active lever presses0.40.41.5-0.30.20.8-0.9-0.40.40.50.50.50.50.6-0.20.60.6-0.7-0.7-0.7-1.2-0.8-0.8-1.0-0.8
Progressive ratio test 1 breakpoint0.30.41.4-0.30.20.8-0.8-0.40.40.40.40.50.40.6-0.20.50.5-0.7-0.7-0.6-1.2-0.7-0.7-0.9-0.8
Progressive ratio test 1 inactive lever presses0.20.31.8-0.1-0.00.4-0.4-0.30.30.30.30.50.40.60.10.40.5-0.5-0.7-0.6-1.4-0.7-0.7-0.7-0.7
Progressive ratio test 2 active lever presses0.40.41.6-1.31.20.9-0.8-0.80.70.70.7-0.7-0.7-0.6-0.40.40.5-0.40.50.3-0.3-0.2-0.10.10.1
Progressive ratio test 2 breakpoint0.40.41.6-1.31.20.9-0.8-0.80.80.80.7-0.7-0.7-0.6-0.40.50.5-0.50.50.3-0.3-0.3-0.20.10.0
Progressive ratio test 2 inactive lever presses0.40.72.1-0.70.61.0-1.0-0.90.91.01.00.00.10.2-0.61.00.9-1.0-0.4-0.5-1.5-1.0-0.9-0.9-0.8
Incentive Sensitization - Responses0.40.61.6-1.31.30.7-0.6-0.80.80.80.7-1.2-1.1-1.1-0.60.40.4-0.30.90.60.20.00.10.50.4
Incentive Sensitization - Breakpoint0.40.51.4-1.21.20.7-0.6-0.90.80.80.8-1.0-0.9-0.9-0.60.50.5-0.40.80.50.1-0.1-0.00.40.3
Sum of active levers in priming session hrs 5-60.30.31.1-0.20.20.5-0.4-0.10.20.20.30.60.70.5-0.40.30.3-0.4-0.6-0.6-1.0-0.5-0.6-0.8-0.7
Progressive ratio0.40.61.6-0.20.21.2-1.3-0.90.91.01.0-0.1-0.00.1-1.01.00.9-1.0-0.3-0.50.1-0.9-0.8-0.9-0.7
Food seeking constrained by brief footshock1.01.23.0-1.71.70.9-0.9-0.70.60.60.5-1.7-1.6-1.7-0.30.30.20.21.61.51.10.60.71.01.1
Seeking ratio, punishment vs. effort1.11.64.1-1.41.3-0.30.50.3-0.3-0.4-0.4-1.6-1.7-1.80.8-0.8-0.71.11.92.01.11.51.61.91.8
Retroperitoneal fat weight2.812.122.31.7-1.7-3.63.54.0-4.1-4.1-4.2-0.3-0.8-0.94.7-4.4-4.34.51.92.53.74.24.23.73.6
Reaction time number correct0.81.54.50.2-0.20.5-0.4-0.80.90.91.01.01.21.1-1.41.21.0-1.4-1.4-1.5-2.1-1.5-1.6-1.5-1.6
Reaction time mean minus median0.30.61.6-1.31.20.9-0.9-0.70.60.60.6-1.2-1.1-1.2-0.30.50.3-0.11.00.80.60.30.30.50.6
Reaction time mean minus median AUC0.30.81.7-1.31.21.3-1.3-1.21.21.21.2-0.9-0.8-0.8-1.01.10.9-0.80.50.2-0.2-0.5-0.5-0.2-0.1
Reaction time num false alarms1.62.24.21.5-1.5-2.01.92.0-2.0-2.1-2.00.80.60.51.8-2.0-1.81.8-0.00.20.31.51.31.00.9
Reaction time num false alarms AUC0.71.12.11.2-1.2-1.51.41.4-1.4-1.4-1.40.60.60.51.2-1.3-1.11.2-0.20.10.00.90.80.50.5
Reaction time trials correct on left0.81.54.50.2-0.20.5-0.4-0.80.90.91.01.01.21.1-1.41.21.0-1.4-1.4-1.5-2.1-1.5-1.6-1.5-1.6
Reaction time trials on left0.81.54.40.2-0.20.5-0.4-0.80.90.91.01.01.21.1-1.41.21.0-1.4-1.4-1.5-2.1-1.5-1.6-1.5-1.6
Reaction time mean0.61.01.90.8-0.8-1.01.01.4-1.4-1.4-1.40.30.10.01.3-1.3-1.21.30.20.20.41.21.10.80.8
Reaction time mean AUC0.61.02.01.0-1.0-1.11.01.4-1.4-1.4-1.40.60.40.41.3-1.2-1.11.2-0.1-0.2-0.11.00.90.50.5
Median of all reaction times1.01.42.81.4-1.4-1.41.31.7-1.7-1.7-1.60.80.60.51.5-1.5-1.31.4-0.2-0.20.11.11.00.60.6
Reaction time omissions0.20.40.70.0-0.0-0.30.20.6-0.6-0.7-0.7-0.3-0.4-0.40.7-0.7-0.60.80.60.70.50.90.80.70.8
Reaction time false alarm rate1.42.03.61.2-1.2-1.61.51.8-1.8-1.8-1.80.20.1-0.01.8-1.9-1.61.80.40.71.21.61.51.21.2
Reaction time premature initiation rate2.23.011.2-1.71.80.5-0.6-0.20.20.1-0.1-2.5-2.6-2.50.5-0.4-0.51.02.52.53.41.61.72.02.2
Reaction time premature initiations0.71.23.5-1.41.50.8-0.8-0.80.70.70.6-1.7-1.6-1.6-0.50.40.30.01.51.41.90.50.50.91.0
Std. dev. reaction times0.71.22.5-0.90.8-0.10.00.4-0.4-0.5-0.5-1.3-1.4-1.50.8-0.8-0.81.11.61.51.41.41.41.51.6
Reaction time trials completed0.81.54.40.2-0.20.5-0.4-0.80.90.91.01.01.21.1-1.41.21.0-1.4-1.4-1.5-2.1-1.5-1.6-1.5-1.6
Reaction time trials AUC0.51.03.20.1-0.10.4-0.3-0.70.70.70.90.81.00.9-1.31.00.9-1.2-1.2-1.3-1.8-1.3-1.3-1.2-1.4
Run reversals in cocaine runway, females3.53.56.4-0.50.5-0.90.91.5-1.6-1.6-1.7-1.3-1.6-1.62.2-1.8-2.12.32.02.12.52.52.52.52.5
Run reversals in cocaine runway, males0.10.10.90.9-0.80.3-0.40.1-0.1-0.0-0.10.40.30.40.20.1-0.0-0.1-0.4-0.30.1-0.3-0.2-0.5-0.3
Latency to leave start box in cocaine runway3.13.67.31.4-1.4-2.42.32.5-2.5-2.5-2.50.70.30.42.7-2.6-2.52.30.20.41.21.91.91.51.4
Latency to leave start box in cocaine runway, F4.04.69.11.0-1.1-2.62.52.6-2.6-2.6-2.70.2-0.3-0.23.0-2.9-2.82.70.91.11.72.42.42.12.0
Latency to leave start box in cocaine runway, M0.20.20.60.7-0.7-0.40.30.4-0.4-0.3-0.30.70.60.80.3-0.2-0.20.0-0.6-0.7-0.0-0.2-0.2-0.4-0.4
Std. dev. time between licks in bursts2.02.76.3-1.61.60.2-0.10.0-0.1-0.2-0.3-2.3-2.3-2.40.6-0.7-0.71.22.42.42.51.81.82.22.2
Total sessions with >9 infusions1.92.35.2-2.22.22.3-2.3-1.91.91.91.8-1.6-1.6-1.4-1.11.51.5-1.21.00.8-0.1-0.7-0.6-0.2-0.0
Short access day 1 total inactive lever presses0.10.10.5-0.70.60.4-0.4-0.20.20.30.2-0.2-0.4-0.20.40.30.3-0.20.10.0-0.6-0.1-0.10.0-0.0
Short access day 10 total inactive lever presses0.20.51.21.1-1.1-0.80.70.8-0.8-0.8-0.70.90.90.80.5-0.5-0.50.4-0.7-0.6-0.30.10.0-0.2-0.2
Short access day 1 total infusions2.33.08.4-2.92.82.3-2.2-2.02.02.01.8-2.3-2.2-2.1-1.11.31.5-1.01.61.30.4-0.3-0.20.30.5
Short access day 10 total infusions1.51.95.0-2.22.22.1-2.1-1.61.61.61.5-1.5-1.4-1.3-1.01.11.2-1.01.00.8-0.1-0.5-0.4-0.20.1
Short access total infusions2.02.65.8-2.42.32.4-2.3-2.12.02.12.0-1.5-1.5-1.2-1.31.61.8-1.50.80.6-0.3-0.9-0.8-0.4-0.3
Short access day 1 locomotion2.02.54.8-1.31.32.0-2.1-2.22.22.22.1-0.8-0.7-0.4-1.72.02.0-1.9-0.0-0.2-0.8-1.6-1.5-1.2-1.0
Short access day 10 total locomotion0.61.12.7-1.41.41.6-1.6-1.31.31.31.2-1.1-0.9-1.0-1.21.20.9-0.80.70.6-0.0-0.4-0.4-0.20.0
Short access total locomotion0.80.91.9-0.60.61.4-1.4-1.21.21.21.2-0.2-0.1-0.0-1.11.31.0-1.2-0.2-0.2-0.9-1.1-1.0-1.0-0.8
One hour access (0.3 mA shock)1.11.32.7-1.51.51.6-1.6-1.51.41.51.4-0.9-0.8-0.7-1.31.51.2-1.10.40.2-0.5-0.8-0.7-0.5-0.3
Compulsive drug intake1.61.94.21.9-1.9-0.60.60.2-0.1-0.10.11.92.12.0-0.70.40.6-0.8-2.0-2.0-1.7-1.4-1.4-1.5-1.7
One hour access (shock baseline)1.42.25.5-2.32.32.1-2.1-1.81.81.81.7-1.5-1.4-1.3-1.41.61.3-1.20.90.70.1-0.6-0.5-0.2-0.0
Social response proportion0.70.81.80.5-0.5-1.31.31.0-1.0-1.0-1.0-0.1-0.3-0.31.1-1.0-1.01.10.50.60.71.11.01.10.9
Social responses1.21.63.0-0.0-0.0-1.11.11.2-1.2-1.3-1.3-0.7-0.8-0.91.6-1.4-1.31.71.21.30.81.71.71.71.6
Social time1.52.14.11.7-1.8-1.81.91.5-1.5-1.4-1.32.01.91.81.0-0.9-1.10.6-1.6-1.3-2.00.0-0.1-0.5-0.7
Soleus weight1.64.69.6-0.00.0-1.81.81.7-1.8-1.8-2.0-1.4-1.7-1.72.2-2.2-2.32.62.22.63.12.82.82.92.8
Bone: stiffness0.50.81.40.9-0.8-1.01.11.2-1.2-1.2-1.20.30.20.11.1-1.1-1.11.10.20.30.61.00.90.70.7
Tibialis anterior weight0.20.81.8-0.30.4-0.40.40.4-0.4-0.4-0.5-1.0-1.1-1.10.7-0.7-0.70.91.21.41.31.21.21.31.3
Time to tail flick, vehicle, before self-admin0.20.30.6-0.70.70.7-0.5-0.60.60.60.6-0.1-0.1-0.1-0.70.60.6-0.6-0.0-0.1-0.5-0.4-0.4-0.3-0.3
Time to tail flick, vehicle, after self-admin1.01.32.4-1.51.41.4-1.3-1.51.51.51.5-0.9-0.9-0.7-1.11.41.4-1.20.40.3-0.8-0.8-0.8-0.3-0.4
Time to tail flick, test, before self-admin0.90.92.3-1.51.50.7-0.6-0.30.20.20.1-1.3-1.4-1.30.2-0.2-0.20.41.31.31.40.80.80.91.0
Time to tail flick, test, after self-admin0.90.92.0-1.11.00.3-0.20.1-0.2-0.2-0.3-1.3-1.4-1.40.6-0.5-0.50.81.41.41.01.21.11.31.3
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.50.60.8-0.9-0.90.90.90.8-0.7-0.7-0.5-0.50.80.8-0.60.30.30.2-0.4-0.4-0.1-0.1
Delta time to tail flick, test, before/after SA0.30.30.70.8-0.8-0.80.80.7-0.7-0.7-0.60.60.50.50.5-0.5-0.40.4-0.4-0.4-0.60.20.10.1-0.0
Tibia length1.64.38.9-1.51.53.0-2.9-2.72.72.72.7-0.6-0.3-0.3-2.72.72.4-2.5-0.4-0.8-1.0-2.1-2.1-1.9-1.6
Ambulatory time before self-admin0.40.61.40.8-0.9-0.70.71.0-1.0-1.0-0.91.11.21.00.6-0.7-0.80.5-0.8-0.7-0.30.20.1-0.3-0.3
Ambulatory time after self-admin2.12.56.50.1-0.21.0-0.9-0.80.90.91.11.61.81.7-1.41.51.4-1.7-2.0-2.0-2.6-2.0-2.0-2.3-2.2
Bone: tissue strength1.51.53.61.2-1.2-0.10.2-0.10.20.20.31.61.71.8-0.60.60.7-1.0-1.8-1.9-1.6-1.4-1.4-1.6-1.7
Total heroin consumption0.20.20.5-0.50.50.6-0.6-0.30.30.30.40.30.30.2-0.30.40.4-0.4-0.4-0.4-0.7-0.4-0.5-0.6-0.5
Bone: trabecular number0.61.02.81.3-1.4-1.00.90.8-0.8-0.7-0.71.71.61.60.3-0.4-0.50.0-1.4-1.5-0.9-0.5-0.5-0.8-0.9
Bone: trabecular spacing0.60.81.5-0.80.91.2-1.2-1.21.21.21.2-0.7-0.6-0.6-1.01.01.0-1.00.30.2-0.0-0.7-0.6-0.4-0.3
Bone: trabecular thickness0.30.41.00.5-0.5-0.70.71.0-1.0-1.0-0.90.50.50.30.8-0.8-0.80.8-0.1-0.10.00.70.60.30.3
Bone: trabecular tissue density2.02.95.40.8-0.8-1.92.02.2-2.2-2.2-2.20.1-0.0-0.32.1-2.2-2.32.30.70.90.92.12.01.71.6
Water consumed over 24 hours0.20.30.80.9-0.9-0.50.50.6-0.5-0.5-0.50.70.70.70.4-0.4-0.40.2-0.6-0.5-0.5-0.0-0.0-0.2-0.2
Number of responses in last shaping day0.80.91.60.1-0.1-0.80.71.0-1.0-1.0-1.0-0.3-0.4-0.51.2-1.2-1.21.20.70.91.01.21.21.01.1