Bone: elastic work

Tags: Physiology · Bone

Project: r01_doug_adams

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr8 117463629 118343328 1 1 4.67e-10 1.58e-01 1.00e+00 Mst1
2 chr8 130995414 132376607 1 1 9.74e-08 2.89e-01 1.00e+00 Clec3b
3 chr9 83390749 84777604 1 1 1.20e-104 2.77e-01 1.00e+00 Retreg2
4 chr10 105235606 106623255 1 1 1.78e-07 5.52e-05 6.68e-01 Slc38a10

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 866.87 1 1 25 0 1.00e+00 Retreg2
BMI without tail 57243.66 1 1 25 0 1.00e+00 Retreg2
Body weight 5.07 3 1 25 0 1.00e+00 Mst1 Retreg2 Slc38a10
Epididymis fat weight 18149.94 2 2 50 0 1.00e+00 Mst1 Retreg2
Glucose 336.01 2 2 50 0 1.00e+00 Mst1 Retreg2
Heart weight 3065.65 1 1 25 0 1.00e+00 Retreg2
Left kidney weight 55046.11 1 1 25 0 1.00e+00 Retreg2
Right kidney weight 20208.48 2 2 50 0 1.00e+00 Mst1 Retreg2
Tail length 9641.1 3 1 25 0 1.00e+00 Mst1 Retreg2 Slc38a10
Length with tail 499.18 3 2 50 0 1.00e+00 Mst1 Retreg2 Slc38a10
Length without tail 23623.74 2 2 50 0 1.00e+00 Mst1 Retreg2
Liver weight, left 1755.51 2 2 50 0 1.00e+00 Mst1 Retreg2
Liver weight, right 35.63 3 3 75 0 1.00e+00 Clec3b Mst1 Retreg2
Parametrial fat weight 181.56 1 1 25 0 1.00e+00 Retreg2
Retroperitoneal fat weight 1325.15 3 2 50 0 1.00e+00 Mst1 Retreg2 Slc38a10
Intraocular pressure 10386.52 1 1 25 0 1.00e+00 Retreg2
Extensor digitorum longus weight 541.05 2 1 25 0 1.00e+00 Mst1 Retreg2
Soleus weight 11.61 2 1 25 0 1.00e+00 Mst1 Retreg2
Tibialis anterior weight 580.28 2 1 25 0 1.00e+00 Mst1 Retreg2
Tibia length 203.05 4 3 75 -0.74 2.57e-01 Clec3b Mst1 Retreg2 Slc38a10
Number of licking bursts 67424.86 1 1 25 0 1.00e+00 Retreg2
Food consumed during 24 hour testing period 17761.06 2 1 25 0 1.00e+00 Mst1 Retreg2
Times rat made contact with spout 71.66 1 1 25 0 1.00e+00 Retreg2
Mean time between licks in bursts 111630.35 1 1 25 0 1.00e+00 Retreg2
Mean num. licks in bursts 28377.53 2 1 25 0 1.00e+00 Clec3b Retreg2
Std. dev. time between licks in bursts 9924.24 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Water consumed over 24 hours 17087.8 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging indifference point 0 sec 19591.07 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging indifference point AUC 25114.54 2 2 50 0 1.00e+00 Mst1 Retreg2
Indifference point function ln k 27906.36 2 2 50 0 1.00e+00 Mst1 Retreg2
Indifference point function log k 27906.36 2 2 50 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 0 sec 20977.37 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 12 sec 1182.87 2 2 50 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 18 sec 20236.6 2 2 50 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 24 sec 37424.62 2 2 50 0 1.00e+00 Mst1 Retreg2
Patch foraging total patch changes 6 sec 3895.78 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging time to switch 0 sec 33247.44 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging water rate 0 sec 60426.37 1 1 25 0 1.00e+00 Retreg2
Patch foraging water rate 12 sec 35322.91 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging water rate 18 sec 16867.27 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging water rate 24 sec 523.92 2 1 25 0 1.00e+00 Mst1 Retreg2
Patch foraging water rate 6 sec 837.86 1 1 25 0 1.00e+00 Retreg2
Locomotor activity 26.79 1 1 25 0 1.00e+00 Mst1
Locomotor testing distance 13845.45 2 2 50 0 1.00e+00 Mst1 Retreg2
Locomotor testing rearing 31715.18 2 2 50 0 1.00e+00 Mst1 Retreg2
Light reinforcement 1 33157.44 2 1 25 0 1.00e+00 Mst1 Retreg2
Light reinforcement 2 18398.05 2 2 50 0 1.00e+00 Mst1 Retreg2
Reaction time number correct 63471.78 1 1 25 0 1.00e+00 Retreg2
Reaction time mean minus median 59976.97 2 1 25 0 1.00e+00 Mst1 Retreg2
Reaction time mean minus median AUC 41337.52 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Reaction time num false alarms 7685.9 2 1 25 0 1.00e+00 Mst1 Retreg2
Reaction time num false alarms AUC 17513.8 2 1 25 0 1.00e+00 Mst1 Retreg2
Reaction time trials correct on left 63471.78 1 1 25 0 1.00e+00 Retreg2
Reaction time trials on left 60883.54 1 1 25 0 1.00e+00 Retreg2
Reaction time mean 14867.01 2 1 25 0 1.00e+00 Clec3b Retreg2
Reaction time mean AUC 19387.31 2 1 25 0 1.00e+00 Clec3b Retreg2
Median of all reaction times 3950.93 2 1 25 0 1.00e+00 Clec3b Retreg2
Reaction time omissions 4184.97 2 1 25 0 1.00e+00 Mst1 Retreg2
Reaction time false alarm rate 111.7 2 1 25 0 1.00e+00 Mst1 Retreg2
Reaction time premature initiation rate 9733.76 1 1 25 0 1.00e+00 Retreg2
Reaction time premature initiations 53743.58 1 1 25 0 1.00e+00 Retreg2
Std. dev. reaction times 20295.68 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Reaction time trials completed 60883.54 1 1 25 0 1.00e+00 Retreg2
Reaction time trials AUC 62130.65 1 1 25 0 1.00e+00 Retreg2
Social response proportion 4397.95 2 1 25 0 1.00e+00 Mst1 Retreg2
Social responses 640.25 2 1 25 0 1.00e+00 Mst1 Retreg2
Social time 5828.31 2 1 25 0 1.00e+00 Mst1 Retreg2
Conditioned locomotion 1400.08 1 1 25 0 1.00e+00 Retreg2
Cocaine response after cond. corrected 19128.47 1 1 25 0 1.00e+00 Retreg2
Cocaine response after cond. not corrected 18571.31 1 1 25 0 1.00e+00 Retreg2
Cocaine response before conditioning 655.41 1 1 25 0 1.00e+00 Retreg2
Saline control response 1639.18 2 2 50 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. active minus inactive responses 7271.32 2 2 50 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. active-inactive response ratio 14361.09 2 1 25 0 1.00e+00 Clec3b Retreg2
Condit. Reinf. active responses 1165.18 2 2 50 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. inactive responses 3650.1 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Condit. Reinf. lever presses 1963.38 2 2 50 0 1.00e+00 Mst1 Retreg2
Condit. Reinf. lever reinforcers received 243.91 2 1 25 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. lever latency 1278.33 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. magazine entry latency 6738.25 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. change in total contacts 39811.91 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. index score 6407.33 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. latency score 8109.24 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. lever contacts 2689.72 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. magazine entry number 2097.69 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries 17558.57 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 5938.34 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. response bias 641.31 2 2 50 0 1.00e+00 Mst1 Retreg2
Conditioned reinforcement - actives 100795.1 1 1 25 0 1.00e+00 Retreg2
Conditioned reinforcement - inactives 32505.31 2 2 50 0 1.00e+00 Mst1 Retreg2
Conditioned locomotion 5172.85 2 1 25 0 1.00e+00 Mst1 Retreg2
Intermittent access intake day 1-15 change 63945.95 2 2 50 0 1.00e+00 Mst1 Retreg2
Intermittent access intake escalation 63041.23 2 2 50 0 1.00e+00 Mst1 Retreg2
Intermittent access intake escalation 2 18091.79 2 1 25 0 1.00e+00 Mst1 Retreg2
Intermitt. access day 1 inactive lever presses 90342.67 2 2 50 0 1.00e+00 Mst1 Retreg2
Intermitt. access day 15 inactive lever presses 123608.2 1 1 25 0 1.00e+00 Retreg2
Intermitt. access escalation Index 46701.01 2 2 50 0 1.00e+00 Mst1 Retreg2
Intermittent access day 1 total infusions 33063.01 2 1 25 0 1.00e+00 Mst1 Retreg2
Intermittent access day 15 total infusions 48731.91 1 1 25 0 1.00e+00 Retreg2
Intermittent access terminal intake (last 3 days) 24800.59 1 1 25 0 1.00e+00 Retreg2
Intermittent access total infusions 181.04 1 1 25 0 1.00e+00 Retreg2
Intermittent access day 1 locomotion 34964.22 1 1 25 0 1.00e+00 Retreg2
Intermittent access day 15 total locomotion 85548.8 1 1 25 0 1.00e+00 Retreg2
Intermittent access total locomotion 62.99 2 1 25 0 1.00e+00 Mst1 Retreg2
Intermittent access standard deviation 56995.61 2 2 50 0 1.00e+00 Mst1 Retreg2
Cocaine induced anxiety 69097.7 1 1 25 0 1.00e+00 Retreg2
Post-drug Anxiety 2380.44 2 1 25 0 1.00e+00 Mst1 Retreg2
Baseline Anxiety 33506.24 1 1 25 0 1.00e+00 Retreg2
Lifetime Intake 1655.49 1 1 25 0 1.00e+00 Retreg2
Incentive Sensitization - Responses 71347.91 1 1 25 0 1.00e+00 Retreg2
Incentive Sensitization - Breakpoint 55273.76 1 1 25 0 1.00e+00 Retreg2
Progressive ratio test 1 active lever presses 31979.35 1 1 25 0 1.00e+00 Retreg2
Progressive ratio test 1 breakpoint 30292.17 1 1 25 0 1.00e+00 Retreg2
Progressive ratio test 1 inactive lever presses 31120.43 2 2 50 0 1.00e+00 Mst1 Retreg2
Progressive ratio test 2 active lever presses 15263.76 1 1 25 0 1.00e+00 Retreg2
Progressive ratio test 2 breakpoint 8542.35 1 1 25 0 1.00e+00 Retreg2
Progressive ratio test 2 inactive lever presses 36254.92 2 1 25 0 1.00e+00 Mst1 Retreg2
Total sessions with >9 infusions 1005.82 2 2 50 0 1.00e+00 Mst1 Retreg2
Short access day 1 total inactive lever presses 19749.92 2 2 50 0 1.00e+00 Mst1 Retreg2
Short access day 10 total inactive lever presses 69453.48 2 2 50 0 1.00e+00 Mst1 Retreg2
Short access day 1 total infusions 19198 2 1 25 0 1.00e+00 Mst1 Retreg2
Short access day 10 total infusions 11366.61 2 2 50 0 1.00e+00 Mst1 Retreg2
Short access total infusions 8778.92 1 1 25 0 1.00e+00 Retreg2
Short access day 1 locomotion 12404.88 2 1 25 0 1.00e+00 Mst1 Retreg2
Short access day 10 total locomotion 44094.34 2 1 25 0 1.00e+00 Mst1 Retreg2
Short access total locomotion 9355.68 2 2 50 0 1.00e+00 Mst1 Retreg2
Compulsive drug intake 9345.9 2 1 25 0 1.00e+00 Mst1 Retreg2
One hour access (0.3 mA shock) 2329.1 1 1 25 0 1.00e+00 Retreg2
One hour access (shock baseline) 54988.81 1 1 25 0 1.00e+00 Retreg2
Number of responses in last shaping day 6812.98 2 1 25 0 1.00e+00 Mst1 Retreg2
Context. condit. distance diff. score 212.47 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, session 1 3523.61 1 1 25 0 1.00e+00 Retreg2
Locomotion distance, session 1 519.22 2 1 25 0 1.00e+00 Clec3b Retreg2
Locomotion velocity, session 2 558.6 4 2 50 -0.85 1.45e-01 Clec3b Mst1 Retreg2 Slc38a10
Locomotion distance, session 2 177.51 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Locomotion velocity, session 3 507.49 1 1 25 0 1.00e+00 Retreg2
Locomotion distance, session 3 4009.46 1 1 25 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 3 464.47 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Stereotopy head waving duration, day 3 966.82 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Locomotion velocity, session 7 210.64 2 2 50 0 1.00e+00 Mst1 Retreg2
Locomotion distance, session 7 339.87 3 2 50 0 1.00e+00 Mst1 Retreg2 Slc38a10
Stereotopy head waving bouts, day 7 1265.52 2 1 25 0 1.00e+00 Clec3b Retreg2
Stereotopy head waving duration, day 7 1068.64 2 1 25 0 1.00e+00 Clec3b Retreg2
Locomotion velocity, session 8 409.23 1 1 25 0 1.00e+00 Retreg2
Locomotion distance, session 8 78.04 2 1 25 0 1.00e+00 Clec3b Retreg2
Degree of sensitization distance 1263.17 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Degree of sensitization stereotypy 690.82 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Condit. Reinf. active minus inactive responses 957.65 1 1 25 0 1.00e+00 Retreg2
Condit. Reinf. active-inactive response ratio 242.03 1 1 25 0 1.00e+00 Retreg2
Condit. Reinf. active responses 1386.95 2 1 25 0 1.00e+00 Clec3b Retreg2
Condit. Reinf. inactive responses 1569.03 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Incentive salience index mean 1189.47 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Condit. Reinf. lever presses 1782.4 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Time in familiar zone, hab. session 1 3733.21 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Time in novel zone, hab. session 1 3088.87 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Total zone transitions, hab. session 1 429.72 1 1 25 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 1 394.1 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 1 266.96 1 1 25 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 2 2966.16 2 2 50 0 1.00e+00 Mst1 Retreg2
Time in novel zone, hab. session 2 3208.33 2 2 50 0 1.00e+00 Mst1 Retreg2
Total zone transitions, hab. session 2 27.67 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Total locomotion distance, hab. session 2 12.4 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Locomotion velocity, hab. session 2 24.52 2 1 25 0 1.00e+00 Clec3b Retreg2
Novel to familiar place preference ratio 5121.94 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Novelty place preference 4986.9 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Time in novel zone, NPP test 3571.61 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Total zone transitions, NPP test 973.86 2 1 25 0 1.00e+00 Clec3b Retreg2
Total locomotion distance, NPP test 846.04 2 1 25 0 1.00e+00 Clec3b Retreg2
Locomotion velocity, NPP test 479.1 2 1 25 0 1.00e+00 Clec3b Retreg2
Pavlov. Cond. lever latency 190.65 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Pavlov. Cond. magazine entry latency 7.58 2 0 0 0 1.00e+00 Clec3b Slc38a10
Pavlov. Cond. change in total contacts 357 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Pavlov. Cond. index score 150.43 3 3 75 0 1.00e+00 Clec3b Mst1 Retreg2
Pavlov. Cond. latency score 155.8 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Pavlov. Cond. lever contacts 260.8 3 3 75 0 1.00e+00 Clec3b Mst1 Retreg2
Pavlov. Cond. magazine entry number 129.57 4 1 25 -0.97 2.66e-02 Clec3b Mst1 Retreg2 Slc38a10
Pavlov. Cond. intertrial magazine entries 82.71 2 2 50 0 1.00e+00 Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 158.53 3 3 75 0 1.00e+00 Clec3b Mst1 Retreg2
Pavlov. Cond. response bias 211.09 3 3 75 0 1.00e+00 Clec3b Mst1 Retreg2
Bone: apparent density 5461.77 1 1 25 0 1.00e+00 Retreg2
Bone surface 3109.3 2 2 50 0 1.00e+00 Mst1 Retreg2
Bone volume 4317.38 2 1 25 0 1.00e+00 Mst1 Retreg2
Bone: connectivity density 838.02 2 1 25 0 1.00e+00 Mst1 Retreg2
Bone: cortical apparent density 6019.36 2 1 25 0 1.00e+00 Clec3b Retreg2
Bone: cortical area 1171.78 4 2 50 -0.82 1.82e-01 Clec3b Mst1 Retreg2 Slc38a10
Bone: cortical porosity 152.1 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Bone: cortical porosity 560.03 2 1 25 0 1.00e+00 Clec3b Retreg2
Bone: cortical thickness 124.05 4 3 75 0.98 1.80e-02 Clec3b Mst1 Retreg2 Slc38a10
Bone: cortical thickness 746.97 4 2 50 0.94 6.29e-02 Clec3b Mst1 Retreg2 Slc38a10
Bone: cortical tissue density 4341.06 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Bone: elastic displacement 3819.66 2 2 50 0 1.00e+00 Clec3b Retreg2
Bone: endosteal estimation 2974.6 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Bone: endosteal perimeter 3958.84 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Bone: final force 423.81 4 2 50 -0.77 2.25e-01 Clec3b Mst1 Retreg2 Slc38a10
Bone: final moment 78.9 4 2 50 -0.57 4.27e-01 Clec3b Mst1 Retreg2 Slc38a10
Bone: marrow area 3147.53 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Bone: maximum diameter 3067.59 2 2 50 0 1.00e+00 Mst1 Retreg2
Bone: maximum force 2928.48 3 2 50 0 1.00e+00 Mst1 Retreg2 Slc38a10
Bone: maximum moment 1520.27 4 2 50 -0.83 1.70e-01 Clec3b Mst1 Retreg2 Slc38a10
Bone: minimum diameter 1375.5 3 2 50 0 1.00e+00 Mst1 Retreg2 Slc38a10
Bone: periosteal estimation 4919.52 2 2 50 0 1.00e+00 Mst1 Retreg2
Bone: periosteal perimeter 3816.77 3 2 50 0 1.00e+00 Mst1 Retreg2 Slc38a10
Bone: post-yield work 4567.25 3 1 25 0 1.00e+00 Clec3b Mst1 Retreg2
Bone: stiffness 4554.23 2 2 50 0 1.00e+00 Mst1 Retreg2
Bone: tissue strength 2995.95 1 1 25 0 1.00e+00 Retreg2
Bone: trabecular number 10739.78 1 1 25 0 1.00e+00 Retreg2
Bone: trabecular spacing 3991.76 2 2 50 0 1.00e+00 Mst1 Retreg2
Bone: trabecular thickness 4257.4 2 2 50 0 1.00e+00 Mst1 Retreg2
Bone: trabecular tissue density 7288.79 2 2 50 0 1.00e+00 Mst1 Retreg2
Breakpoint value in progressive ratio session 12547.56 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Distance traveled before self-admin 25269.61 2 1 25 0 1.00e+00 Mst1 Retreg2
Distance traveled after self-admin 32464.08 1 1 25 0 1.00e+00 Retreg2
Delta time in closed arm before/after self-admin 126.71 2 1 25 0 1.00e+00 Mst1 Retreg2
Delta time in open arm before/after self-admin 7570.03 2 1 25 0 1.00e+00 Mst1 Retreg2
Diff in mean of infusions in LGA sessions 18336.8 2 2 50 0 1.00e+00 Mst1 Retreg2
Extinction: sum of active levers before priming 9485.06 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Active lever presses in extinction session 6 384.74 2 2 50 0 1.00e+00 Mst1 Retreg2
Delta distance traveled before/after self-admin 2940.47 1 1 25 0 1.00e+00 Retreg2
Delta ambulatory time before/after self-admin 30849.75 1 1 25 0 1.00e+00 Retreg2
Time in closed arm before self-admin 13457.43 2 2 50 0 1.00e+00 Mst1 Retreg2
Time in closed arm after self-admin 2326.29 2 2 50 0 1.00e+00 Mst1 Retreg2
Time in open arm before self-admin 4379.48 2 1 25 0 1.00e+00 Mst1 Retreg2
Time in open arm after self-admin 277.78 2 2 50 0 1.00e+00 Mst1 Retreg2
Sum of active levers in priming session hrs 5-6 493 2 1 25 0 1.00e+00 Clec3b Retreg2
Time to tail flick, vehicle, before self-admin 4467.96 3 2 50 0 1.00e+00 Clec3b Mst1 Retreg2
Time to tail flick, vehicle, after self-admin 21074.56 2 1 25 0 1.00e+00 Retreg2 Slc38a10
Time to tail flick, test, before self-admin 4073.42 2 1 25 0 1.00e+00 Mst1 Retreg2
Time to tail flick, test, after self-admin 702.8 2 1 25 0 1.00e+00 Mst1 Retreg2
Delta time to tail flick, vehicle, before/after SA 4924 2 2 50 0 1.00e+00 Mst1 Retreg2
Delta time to tail flick, test, before/after SA 7847.8 2 1 25 0 1.00e+00 Mst1 Retreg2
Ambulatory time before self-admin 78874.38 1 1 25 0 1.00e+00 Retreg2
Ambulatory time after self-admin 13311.39 2 1 25 0 1.00e+00 Mst1 Retreg2
Total heroin consumption 125.52 2 1 25 0 1.00e+00 Clec3b Retreg2
Area under the delay curve 24791.27 1 1 25 0 1.00e+00 Retreg2
Delay disc. indifference point, 0s delay 2159.25 1 1 25 0 1.00e+00 Retreg2
Delay disc. indifference point, 16s delay 21959.9 1 1 25 0 1.00e+00 Retreg2
Delay disc. indifference point, 2s delay 155.27 1 1 25 0 1.00e+00 Retreg2
Delay disc. indifference point, 24s delay 16224.57 2 1 25 0 1.00e+00 Clec3b Retreg2
Delay disc. indifference point, 4s delay 311.73 2 1 25 0 1.00e+00 Mst1 Retreg2
Delay disc. indifference point, 8s delay 33362.4 1 1 25 0 1.00e+00 Retreg2
Delay discount exponential model param 16922.54 1 1 25 0 1.00e+00 Retreg2
Delay discount hyperbolic model param 12277.65 1 1 25 0 1.00e+00 Retreg2
Fecal boli incidents, locomotor time 1 61202.36 1 1 25 0 1.00e+00 Retreg2
Change in fecal boli incidents, locomotor task 5669.94 1 1 25 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 1 13009.3 1 1 25 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 1 10785.17 1 1 25 0 1.00e+00 Retreg2
Total resting periods, locomotor time 1 2793.59 1 1 25 0 1.00e+00 Retreg2
Rest time, locomotor task time 1 22349.64 1 1 25 0 1.00e+00 Retreg2
Distance moved, locomotor task time 1 68821.85 1 1 25 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 1 142354.07 1 1 25 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 2 71159.6 1 1 25 0 1.00e+00 Retreg2
Bouts of movement, locomotor time 2 82029.05 1 1 25 0 1.00e+00 Retreg2
Total resting periods, locomotor time 2 99042.67 1 1 25 0 1.00e+00 Retreg2
Rest time, locomotor task time 2 25503.09 1 1 25 0 1.00e+00 Retreg2
Distance moved, locomotor task time 2 8477.87 1 1 25 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 2 53555.35 1 1 25 0 1.00e+00 Retreg2
Weight adjusted by age 70782.25 1 1 25 0 1.00e+00 Retreg2
Seeking ratio, delayed vs. immediate footshock 13445.31 1 1 25 0 1.00e+00 Retreg2
Locomotion in novel chamber 3903.37 1 1 25 0 1.00e+00 Retreg2
Locomotion in novel chamber post-restriction 65422.89 1 1 25 0 1.00e+00 Retreg2
Progressive ratio 67888.93 1 1 25 0 1.00e+00 Retreg2
Food seeking constrained by brief footshock 940.75 2 1 25 0 1.00e+00 Clec3b Retreg2
Seeking ratio, punishment vs. effort 41283.25 1 1 25 0 1.00e+00 Retreg2
Run reversals in cocaine runway, females 9406.04 1 1 25 0 1.00e+00 Retreg2
Run reversals in cocaine runway, males 7664.74 1 1 25 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway 16290.75 1 1 25 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, F 7166.92 1 1 25 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway, M 1716.51 1 1 25 0 1.00e+00 Retreg2
Co content in liver 1133.25 1 1 25 0 1.00e+00 Retreg2
Cu content in liver 25.23 2 1 25 0 1.00e+00 Clec3b Retreg2
Fe content in liver 1344.53 1 1 25 0 1.00e+00 Retreg2
K content in liver 1519.62 1 1 25 0 1.00e+00 Retreg2
Mg content in liver 6026.97 1 1 25 0 1.00e+00 Retreg2
Mn content in liver 1009.39 1 1 25 0 1.00e+00 Retreg2
Na content in liver 4018.36 1 1 25 0 1.00e+00 Retreg2
Rb content in liver 47.89 2 1 25 0 1.00e+00 Clec3b Retreg2
Zn content in liver 3745.55 1 1 25 0 1.00e+00 Retreg2

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 0 0 1.27
Adipose alternative TSS 0 0 1.3
Adipose gene expression 0 0 1.31
Adipose isoform ratio 0 0 1.3
Adipose intron excision ratio 0 0 1.17
Adipose mRNA stability 0 0 1.34
BLA alternative polyA 0 0 1.34
BLA alternative TSS 0 0 1.26
BLA gene expression 0 0 1.31
BLA isoform ratio 0 0 1.42
BLA intron excision ratio 0 0 1.23
BLA mRNA stability 0 0 1.26
Brain alternative polyA 0 0 1.37
Brain alternative TSS 0 0 1.32
Brain gene expression 0 0 1.31
Brain isoform ratio 0 0 1.37
Brain intron excision ratio 0 0 1.31
Brain mRNA stability 0 0 1.31
Eye alternative polyA 0 0 1.55
Eye alternative TSS 0 0 1.3
Eye gene expression 0 0 1.28
Eye isoform ratio 0 0 1.38
Eye intron excision ratio 0 0 1.36
Eye mRNA stability 0 0 1.22
IC alternative polyA 0 0 1.35
IC alternative TSS 0 0 1.31
IC gene expression 1 0 1.32
IC isoform ratio 0 0 1.39
IC intron excision ratio 0 0 1.37
IC mRNA stability 0 0 1.25
IL alternative polyA 0 0 1.37
IL alternative TSS 0 0 1.27
IL gene expression 0 0 1.31
IL isoform ratio 0 0 1.37
IL intron excision ratio 0 0 1.28
IL mRNA stability 0 0 1.29
LHb alternative polyA 0 0 1.36
LHb alternative TSS 0 0 1.12
LHb gene expression 0 0 1.32
LHb isoform ratio 0 0 1.26
LHb intron excision ratio 0 0 1.22
LHb mRNA stability 0 0 1.32
Liver alternative polyA 0 0 1.33
Liver alternative TSS 0 0 1.33
Liver gene expression 0 0 1.34
Liver isoform ratio 1 0 1.42
Liver intron excision ratio 0 0 1.29
Liver mRNA stability 0 0 1.36
NAcc alternative polyA 1 0 1.44
NAcc alternative TSS 0 0 1.27
NAcc gene expression 0 0 1.32
NAcc isoform ratio 0 0 1.35
NAcc intron excision ratio 0 0 1.29
NAcc mRNA stability 0 0 1.31
OFC alternative polyA 0 0 1.3
OFC alternative TSS 0 0 1.17
OFC gene expression 0 0 1.35
OFC isoform ratio 0 0 1.33
OFC intron excision ratio 0 0 1.29
OFC mRNA stability 0 0 1.32
PL alternative polyA 0 0 1.43
PL alternative TSS 0 0 1.3
PL gene expression 0 0 1.32
PL isoform ratio 0 0 1.38
PL intron excision ratio 0 0 1.31
PL mRNA stability 0 0 1.27
pVTA alternative polyA 0 0 1.36
pVTA alternative TSS 0 0 1.27
pVTA gene expression 0 0 1.33
pVTA isoform ratio 0 0 1.38
pVTA intron excision ratio 0 0 1.33
pVTA mRNA stability 0 0 1.27
RMTg alternative polyA 0 0 1.36
RMTg alternative TSS 1 0.2 1.3
RMTg gene expression 0 0 1.32
RMTg isoform ratio 0 0 1.33
RMTg intron excision ratio 0 0 1.43
RMTg mRNA stability 0 0 1.3